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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7310615
log Bayes Factor = 134.377
Chromosome 12   position 111,865,049  (GRCh37) Explore rs7310615 on Ensembl!
Variant rs7310615 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
C77.3 Axillary and upper limb lymph nodes
1.000 0.000 0.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.000 1.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.000 1.000
I25.1 Atherosclerotic heart disease
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
Z95.5 Presence of coronary angioplasty implant and graft
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
I10 Essential (primary) hypertension
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I21 Acute myocardial infarction
0.000 0.000 1.000
Z95 Presence of cardiac and vascular implants and grafts
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
Chapter IX Diseases of the circulatory system
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.000 1.000
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.000 1.000
I25.2 Old myocardial infarction
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
I10-I15 Hypertensive diseases
0.000 0.000 1.000
E20-E35 Disorders of other endocrine glands
0.000 0.000 1.000
Z95.1 Presence of aortocoronary bypass graft
0.000 0.000 1.000
Z95.2 Presence of prosthetic heart valve
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.001 0.999
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.999 0.001 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.999 0.001 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.001 0.999
Z95.4 Presence of other heart-valve replacement
0.000 0.002 0.998
C50 Malignant neoplasm of breast
0.998 0.002 0.000
# Top node
0.000 0.002 0.998
I20.9 Angina pectoris, unspecified
0.000 0.003 0.997
I20 Angina pectoris
0.000 0.003 0.997
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.004 0.996
D55-D59 Haemolytic anaemias
0.000 0.005 0.995
C50-C50 Malignant neoplasm of breast
0.995 0.005 0.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.005 0.995
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.007 0.993
Chapter II Neoplasms
0.993 0.007 0.000
E10.9 Without complications
0.000 0.009 0.991
E27 Other disorders of adrenal gland
0.000 0.009 0.991
I74 Arterial embolism and thrombosis
0.000 0.010 0.990
E10.5 With peripheral circulatory complications
0.000 0.012 0.988
I21.9 Acute myocardial infarction, unspecified
0.000 0.013 0.987
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.013 0.987
D75 Other diseases of blood and blood-forming organs
0.000 0.014 0.986
I25.5 Ischaemic cardiomyopathy
0.000 0.017 0.983
E06 Thyroiditis
0.000 0.017 0.983
C50.9 Breast, unspecified
0.979 0.021 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.022 0.978
I22 Subsequent myocardial infarction
0.000 0.023 0.977
D75.1 Secondary polycythaemia
0.000 0.024 0.976
C50.4 Upper-outer quadrant of breast
0.975 0.025 0.000
D59 Acquired haemolytic anaemia
0.000 0.025 0.975
E10.1 With ketoacidosis
0.000 0.025 0.975
C50.8 Overlapping lesion of breast
0.973 0.027 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.000 0.028 0.972
Chapter VI Diseases of the nervous system
0.000 0.028 0.972
G81 Hemiplegia
0.000 0.030 0.970
G81.9 Hemiplegia, unspecified
0.000 0.030 0.970
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.034 0.966
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.966 0.034 0.000
E10.3 With ophthalmic complications
0.000 0.035 0.965
E10.4 With neurological complications
0.000 0.037 0.963
E06.3 Autoimmune thyroiditis
0.000 0.039 0.961
K90 Intestinal malabsorption
0.000 0.041 0.959
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.957 0.043 0.000
C79 Secondary malignant neoplasm of other sites
0.956 0.044 0.000
D59.1 Other autoimmune haemolytic anaemias
0.000 0.045 0.955
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.045 0.955
C78.7 Secondary malignant neoplasm of liver
0.955 0.045 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.048 0.952
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.049 0.951
Chapter XI Diseases of the digestive system
0.000 0.054 0.946
K90-K93 Other diseases of the digestive system
0.000 0.055 0.945
C77.9 Lymph node, unspecified
0.944 0.056 0.000
K70-K77 Diseases of liver
0.000 0.057 0.943
K74 Fibrosis and cirrhosis of liver
0.000 0.060 0.940
E23 Hypofunction and other disorders of pituitary gland
0.000 0.061 0.939
D75.2 Essential thrombocytosis
0.000 0.062 0.938
C50.2 Upper-inner quadrant of breast
0.933 0.067 0.000
G70-G73 Diseases of myoneural junction and muscle
0.000 0.072 0.928
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.928 0.072 0.000
G20-G26 Extrapyramidal and movement disorders
0.000 0.073 0.927
I74.5 Embolism and thrombosis of iliac artery
0.000 0.074 0.926
K74.3 Primary biliary cirrhosis
0.000 0.074 0.926
M06 Other rheumatoid arthritis
0.000 0.074 0.926
G83 Other paralytic syndromes
0.000 0.083 0.917
G24 Dystonia
0.000 0.084 0.916
Z95.8 Presence of other cardiac and vascular implants and grafts
0.000 0.087 0.913
E10.2 With renal complications
0.000 0.090 0.910
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.091 0.909
C84 Peripheral and cutaneous T-cell lymphomas
0.908 0.092 0.000
M05-M14 Inflammatory polyarthropathies
0.000 0.092 0.908
C50.0 Nipple and areola
0.906 0.094 0.000
E10.0 With coma
0.000 0.095 0.905
K73 Chronic hepatitis, not elsewhere classified
0.000 0.096 0.904
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.096 0.904
D58 Other hereditary haemolytic anaemias
0.000 0.097 0.903
G24.9 Dystonia, unspecified
0.000 0.099 0.900
C50.1 Central portion of breast
0.900 0.100 0.000
C15-C26 Malignant neoplasms of digestive organs
0.897 0.103 0.000
M05 Seropositive rheumatoid arthritis
0.000 0.104 0.896
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.111 0.889
D56 Thalassaemia
0.000 0.111 0.889
C79.7 Secondary malignant neoplasm of adrenal gland
0.888 0.112 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.114 0.886
I25.3 Aneurysm of heart
0.000 0.115 0.885
I73 Other peripheral vascular diseases
0.000 0.115 0.885
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.118 0.882
E50-E64 Other nutritional deficiencies
0.000 0.118 0.882
E34 Other endocrine disorders
0.000 0.120 0.880
G83.4 Cauda equina syndrome
0.000 0.127 0.873
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.872 0.128 0.000
E28 Ovarian dysfunction
0.000 0.132 0.868
D60-D64 Aplastic and other anaemias
0.000 0.134 0.866
I73.9 Peripheral vascular disease, unspecified
0.000 0.136 0.864
K75 Other inflammatory liver diseases
0.000 0.136 0.864
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.137 0.863
E27.2 Addisonian crisis
0.000 0.137 0.863
M07 Psoriatic and enteropathic arthropathies
0.000 0.138 0.862
I77 Other disorders of arteries and arterioles
0.000 0.138 0.862
I05-I09 Chronic rheumatic heart diseases
0.000 0.138 0.862
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.859 0.141 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.141 0.859
E23.6 Other disorders of pituitary gland
0.000 0.146 0.854
C77.8 Lymph nodes of multiple regions
0.851 0.149 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.149 0.851
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.149 0.851
E07 Other disorders of thyroid
0.000 0.150 0.850
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.150 0.850
I23 Certain current complications following acute myocardial infarction
0.000 0.152 0.848
D63.8 Anaemia in other chronic diseases classified elsewhere
0.000 0.153 0.847
D80-D89 Certain disorders involving the immune mechanism
0.000 0.155 0.845
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.155 0.845
C79.8 Secondary malignant neoplasm of other specified sites
0.844 0.156 0.000
E22 Hyperfunction of pituitary gland
0.000 0.156 0.844
E23.2 Diabetes insipidus
0.000 0.157 0.843
C85.7 Other specified types of non-Hodgkin's lymphoma
0.842 0.157 0.000
G72 Other myopathies
0.000 0.162 0.838
E27.8 Other specified disorders of adrenal gland
0.000 0.164 0.836
C20 Malignant neoplasm of rectum
0.836 0.164 0.000
I12 Hypertensive renal disease
0.000 0.166 0.834
M07.3 Other psoriatic arthropathies
0.000 0.167 0.833
C76 Malignant neoplasm of other and ill-defined sites
0.832 0.168 0.000
G71 Primary disorders of muscles
0.000 0.170 0.830
C18 Malignant neoplasm of colon
0.829 0.171 0.000
G80 Infantile cerebral palsy
0.000 0.172 0.827
E20 Hypoparathyroidism
0.000 0.178 0.822
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.820 0.180 0.000
K74.0 Hepatic fibrosis
0.000 0.184 0.816
K74.5 Biliary cirrhosis, unspecified
0.000 0.184 0.816
E06.9 Thyroiditis, unspecified
0.000 0.184 0.816
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.184 0.816
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.185 0.815
C78.2 Secondary malignant neoplasm of pleura
0.814 0.186 0.000
M06.4 Inflammatory polyarthropathy
0.000 0.186 0.814
L40.5 Arthropathic psoriasis
0.000 0.189 0.811
L40 Psoriasis
0.000 0.190 0.810
C51-C58 Malignant neoplasms of female genital organs
0.810 0.190 0.000
D69 Purpura and other haemorrhagic conditions
0.000 0.192 0.808
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.193 0.807
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.193 0.807
D58.9 Hereditary haemolytic anaemia, unspecified
0.000 0.193 0.807
C84.0 Mycosis fungoides
0.806 0.194 0.000
K75.4 Autoimmune hepatitis
0.000 0.195 0.805
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.197 0.803
L40-L45 Papulosquamous disorders
0.000 0.199 0.801
E21.3 Hyperparathyroidism, unspecified
0.000 0.201 0.799
E31 Polyglandular dysfunction
0.000 0.202 0.798
I77.6 Arteritis, unspecified
0.000 0.204 0.796
G24.5 Blepharospasm
0.000 0.205 0.795
D75.8 Other specified diseases of blood and blood-forming organs
0.000 0.205 0.795
C18.2 Ascending colon
0.795 0.205 0.000
D56.3 Thalassaemia trait
0.000 0.206 0.794
C90 Multiple myeloma and malignant plasma cell neoplasms
0.793 0.207 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.792 0.208 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.792 0.208 0.000
D73 Diseases of spleen
0.000 0.208 0.792
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.212 0.788
Z95.3 Presence of xenogenic heart valve
0.000 0.214 0.786
D86 Sarcoidosis
0.000 0.216 0.784
C18.9 Colon, unspecified
0.784 0.216 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.782 0.218 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.218 0.781
K40-K46 Hernia
0.000 0.218 0.782
E07.9 Disorder of thyroid, unspecified
0.000 0.224 0.776
G72.9 Myopathy, unspecified
0.000 0.229 0.771
I25.4 Coronary artery aneurysm
0.000 0.229 0.770
E03.1 Congenital hypothyroidism without goitre
0.000 0.230 0.770
I25.6 Silent myocardial ischaemia
0.000 0.230 0.770
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.770 0.230 0.000
D59.9 Acquired haemolytic anaemia, unspecified
0.000 0.231 0.769
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.233 0.767
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.767 0.233 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.766 0.234 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.236 0.764
G83.9 Paralytic syndrome, unspecified
0.000 0.237 0.763
L40.9 Psoriasis, unspecified
0.000 0.237 0.763
I07 Rheumatic tricuspid valve diseases
0.000 0.238 0.762
I15 Secondary hypertension
0.000 0.239 0.761
C84.4 Peripheral T-cell lymphoma
0.759 0.241 0.000
E58 Dietary calcium deficiency
0.000 0.241 0.759
E06.1 Subacute thyroiditis
0.000 0.244 0.756
E28.3 Primary ovarian failure
0.000 0.244 0.756
E03.8 Other specified hypothyroidism
0.000 0.245 0.755
I77.1 Stricture of artery
0.000 0.247 0.753
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.247 0.753
K41 Femoral hernia
0.000 0.249 0.751
E22.1 Hyperprolactinaemia
0.000 0.249 0.751
I05 Rheumatic mitral valve diseases
0.000 0.251 0.749
D59.0 Drug-induced autoimmune haemolytic anaemia
0.000 0.251 0.748
C23 Malignant neoplasm of gallbladder
0.747 0.253 0.000
C84.5 Other and unspecified T-cell lymphomas
0.747 0.253 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.746 0.254 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.746 0.254 0.000
E34.9 Endocrine disorder, unspecified
0.000 0.256 0.744
C94 Other leukaemias of specified cell type
0.743 0.257 0.000
D75.9 Disease of blood and blood-forming organs, unspecified
0.000 0.260 0.740
I23.8 Other current complications following acute myocardial infarction
0.000 0.261 0.739
G25 Other extrapyramidal and movement disorders
0.000 0.264 0.736
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene
0.000 0.266 0.734
E10.8 With unspecified complications
0.000 0.268 0.732
G80.9 Infantile cerebral palsy, unspecified
0.000 0.268 0.732
C86 Other specified types of T/NK-cell lymphoma
0.731 0.269 0.000
E34.0 Carcinoid syndrome
0.000 0.270 0.730
E40-E46 Malnutrition
0.000 0.272 0.728
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.274 0.726
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.274 0.726
C51 Malignant neoplasm of vulva
0.724 0.276 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.276 0.724
K44 Diaphragmatic hernia
0.000 0.277 0.723
K73.9 Chronic hepatitis, unspecified
0.000 0.277 0.723
E53 Deficiency of other B group vitamins
0.000 0.278 0.722
D69.4 Other primary thrombocytopenia
0.000 0.279 0.721
G71.1 Myotonic disorders
0.000 0.279 0.721
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.281 0.719
C21 Malignant neoplasm of anus and anal canal
0.718 0.282 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.283 0.717
E30 Disorders of puberty, not elsewhere classified
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E25 Adrenogenital disorders
0.000 0.284 0.716
D86.9 Sarcoidosis, unspecified
0.000 0.285 0.715
E05.5 Thyroid crisis or storm
0.000 0.286 0.714
E05.4 Thyrotoxicosis factitia
0.000 0.286 0.714
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.286 0.714
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.286 0.714
C49 Malignant neoplasm of other connective and soft tissue
0.714 0.286 0.000
D55 Anaemia due to enzyme disorders
0.000 0.286 0.713
E23.0 Hypopituitarism
0.000 0.288 0.712
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.289 0.711
D57 Sickle-cell disorders
0.000 0.289 0.711
D58.0 Hereditary spherocytosis
0.000 0.289 0.711
E27.5 Adrenomedullary hyperfunction
0.000 0.289 0.711
E27.0 Other adrenocortical overactivity
0.000 0.289 0.711
I21.4 Acute subendocardial myocardial infarction
0.000 0.291 0.709
D74 Methaemoglobinaemia
0.000 0.293 0.707
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.000 0.293 0.707
D71 Functional disorders of polymorphonuclear neutrophils
0.000 0.293 0.707
M12 Other specific arthropathies
0.000 0.293 0.707
E06.4 Drug-induced thyroiditis
0.000 0.295 0.705
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.295 0.705
E06.0 Acute thyroiditis
0.000 0.295 0.705
G24.1 Idiopathic familial dystonia
0.000 0.295 0.704
C76.0 Head, face and neck
0.704 0.295 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.297 0.703
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.298 0.702
D59.8 Other acquired haemolytic anaemias
0.000 0.301 0.699
D59.6 Haemoglobinuria due to haemolysis from other external causes
0.000 0.301 0.699
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]
0.000 0.301 0.699
D59.3 Haemolytic-uraemic syndrome
0.000 0.301 0.699
D59.2 Drug-induced nonautoimmune haemolytic anaemia
0.000 0.301 0.699
D75.0 Familial erythrocytosis
0.000 0.302 0.698
C97 Malignant neoplasms of independent (primary) multiple sites
0.696 0.304 0.000
G81.0 Flaccid hemiplegia
0.000 0.304 0.695
I13 Hypertensive heart and renal disease
0.000 0.304 0.695
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.305 0.695
E20.9 Hypoparathyroidism, unspecified
0.000 0.305 0.695
E32 Diseases of thymus
0.000 0.306 0.694
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.693 0.307 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.309 0.691
K71 Toxic liver disease
0.000 0.309 0.690
K74.6 Other and unspecified cirrhosis of liver
0.000 0.310 0.690
C18.3 Hepatic flexure
0.690 0.310 0.000
I07.1 Tricuspid insufficiency
0.000 0.310 0.690
C77.2 Intra-abdominal lymph nodes
0.688 0.312 0.000
G70 Myasthenia gravis and other myoneural disorders
0.000 0.312 0.688
K90.3 Pancreatic steatorrhoea
0.000 0.313 0.687
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.313 0.687
K90.1 Tropical sprue
0.000 0.313 0.687
D86.0 Sarcoidosis of lung
0.000 0.313 0.687
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.313 0.687
K44.9 Diaphragmatic hernia without obstruction or gangrene
0.000 0.314 0.686
D56.1 Beta thalassaemia
0.000 0.315 0.685
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.684 0.316 0.000
D73.3 Abscess of spleen
0.000 0.318 0.682
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.319 0.681
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.679 0.321 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.679 0.321 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.321 0.678
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.322 0.678
M05.1 Rheumatoid lung disease
0.000 0.322 0.678
G80.2 Infantile hemiplegia
0.000 0.325 0.675
E21.0 Primary hyperparathyroidism
0.000 0.326 0.674
E06.5 Other chronic thyroiditis
0.000 0.326 0.674
K77 Liver disorders in diseases classified elsewhere
0.000 0.326 0.674
K74.4 Secondary biliary cirrhosis
0.000 0.326 0.674
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.326 0.674
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.327 0.673
E23.1 Drug-induced hypopituitarism
0.000 0.327 0.673
C17 Malignant neoplasm of small intestine
0.673 0.327 0.000
C88 Malignant immunoproliferative diseases
0.672 0.328 0.000
I12.0 Hypertensive renal disease with renal failure
0.000 0.330 0.670
G83.1 Monoplegia of lower limb
0.000 0.330 0.670
C77.4 Inguinal and lower limb lymph nodes
0.669 0.331 0.000
D58.2 Other haemoglobinopathies
0.000 0.331 0.669
I22.8 Subsequent myocardial infarction of other sites
0.000 0.331 0.669
K74.1 Hepatic sclerosis
0.000 0.332 0.668
C90.1 Plasma cell leukaemia
0.668 0.332 0.000
C51.9 Vulva, unspecified
0.668 0.332 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.333 0.667
I05.0 Mitral stenosis
0.000 0.333 0.667
L42 Pityriasis rosea
0.000 0.333 0.667
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.666 0.334 0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.000 0.334 0.666
C85.0 Lymphosarcoma
0.666 0.334 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.335 0.665
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.335 0.665
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.000 0.335 0.665
G22 Parkinsonism in diseases classified elsewhere
0.000 0.335 0.665
M06.2 Rheumatoid bursitis
0.000 0.336 0.664
M06.1 Adult-onset Still's disease
0.000 0.336 0.664
E51 Thiamine deficiency
0.000 0.337 0.663
C93 Monocytic leukaemia
0.662 0.338 0.000
G72.8 Other specified myopathies
0.000 0.338 0.662
I12.9 Hypertensive renal disease without renal failure
0.000 0.338 0.662
E28.2 Polycystic ovarian syndrome
0.000 0.339 0.661
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.340 0.660
E55 Vitamin D deficiency
0.000 0.341 0.659
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.341 0.659
C26.9 Ill-defined sites within the digestive system
0.658 0.341 0.000
G83.5 Locked-in syndrome
0.000 0.342 0.657
G83.3 Monoplegia, unspecified
0.000 0.342 0.657
G83.0 Diplegia of upper limbs
0.000 0.342 0.657
C95 Leukaemia of unspecified cell type
0.657 0.343 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.343 0.657
I77.2 Rupture of artery
0.000 0.343 0.657
E26 Hyperaldosteronism
0.000 0.343 0.657
G24.4 Idiopathic orofacial dystonia
0.000 0.343 0.657
G24.2 Idiopathic nonfamilial dystonia
0.000 0.343 0.657
I00-I02 Acute rheumatic fever
0.000 0.344 0.656
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.344 0.655
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.000 0.345 0.655
E61 Deficiency of other nutrient elements
0.000 0.346 0.654
E31.0 Autoimmune polyglandular failure
0.000 0.346 0.654
I77.0 Arteriovenous fistula, acquired
0.000 0.347 0.653
K90.8 Other intestinal malabsorption
0.000 0.348 0.652
C49.3 Connective and soft tissue of thorax
0.651 0.348 0.000
C84.9 Mature T/NK-cell lymphoma, unspecified
0.651 0.349 0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.651 0.349 0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.651 0.349 0.000
C84.3 Lymphoepithelioid lymphoma
0.651 0.349 0.000
C84.2 T-zone lymphoma
0.651 0.349 0.000
C84.1 Sezary's diease
0.651 0.349 0.000
M08 Juvenile arthritis
0.000 0.349 0.651
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.349 0.651
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.349 0.651
E10.6 With other specified complications
0.000 0.350 0.649
I05.2 Mitral stenosis with insufficiency
0.000 0.351 0.649
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.351 0.648
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.351 0.648
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.352 0.648
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.352 0.647
D58.8 Other specified hereditary haemolytic anaemias
0.000 0.353 0.647
D58.1 Hereditary elliptocytosis
0.000 0.353 0.647
G24.3 Spasmodic torticollis
0.000 0.353 0.647
G71.0 Muscular dystrophy
0.000 0.354 0.646
E14 Unspecified diabetes mellitus
0.000 0.354 0.646
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.355 0.645
G23 Other degenerative diseases of basal ganglia
0.000 0.356 0.644
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.357 0.643
M05.0 Felty's syndrome
0.000 0.357 0.643
M05.8 Other seropositive rheumatoid arthritis
0.000 0.360 0.640
D59.4 Other nonautoimmune haemolytic anaemias
0.000 0.360 0.639
D83 Common variable immunodeficiency
0.000 0.361 0.639
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.362 0.638
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.362 0.638
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.362 0.638
D56.9 Thalassaemia, unspecified
0.000 0.363 0.637
D56.8 Other thalassaemias
0.000 0.363 0.637
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]
0.000 0.363 0.637
D56.2 Delta-beta thalassaemia
0.000 0.363 0.637
D56.0 Alpha thalassaemia
0.000 0.363 0.637
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.364 0.636
E27.9 Disorder of adrenal gland, unspecified
0.000 0.364 0.636
G71.3 Mitochondrial myopathy, not elsewhere classified
0.000 0.365 0.635
C81 Hodgkin's disease
0.634 0.366 0.000
I70 Atherosclerosis
0.000 0.367 0.633
C74 Malignant neoplasm of adrenal gland
0.633 0.367 0.000
C76.1 Thorax
0.633 0.367 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.368 0.632
E63 Other nutritional deficiencies
0.000 0.368 0.632
E50 Vitamin A deficiency
0.000 0.368 0.632
E60 Dietary zinc deficiency
0.000 0.368 0.632
E59 Dietary selenium deficiency
0.000 0.368 0.632
E52 Niacin deficiency [pellagra]
0.000 0.368 0.632
C82.0 Small cleaved cell, follicular
0.632 0.368 0.000
E34.5 Androgen resistance syndrome
0.000 0.369 0.631
E34.4 Constitutional tall stature
0.000 0.369 0.631
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.369 0.631
E34.1 Other hypersecretion of intestinal hormones
0.000 0.369 0.631
E21.2 Other hyperparathyroidism
0.000 0.371 0.629
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.629 0.371 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.371 0.629
E34.3 Short stature, not elsewhere classified
0.000 0.371 0.629
D73.4 Cyst of spleen
0.000 0.372 0.628
G24.0 Drug-induced dystonia
0.000 0.374 0.626
D73.1 Hypersplenism
0.000 0.374 0.626
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.374 0.626
M10 Gout
0.000 0.375 0.625
M06.8 Other specified rheumatoid arthritis
0.000 0.376 0.624
E10.7 With multiple complications
0.000 0.376 0.624
C21.8 Overlapping lesion of rectum, anus and anal canal
0.624 0.376 0.000
C84.8 Cutaneous T-cell lymphoma, unspecified
0.623 0.377 0.000
E28.9 Ovarian dysfunction, unspecified
0.000 0.378 0.622
E28.8 Other ovarian dysfunction
0.000 0.378 0.622
E28.1 Androgen excess
0.000 0.378 0.622
E28.0 Oestrogen excess
0.000 0.378 0.622
E34.8 Other specified endocrine disorders
0.000 0.378 0.621
G25.0 Essential tremor
0.000 0.379 0.621
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.379 0.621
D82 Immunodeficiency associated with other major defects
0.000 0.380 0.620
K75.2 Nonspecific reactive hepatitis
0.000 0.380 0.620
K75.1 Phlebitis of portal vein
0.000 0.380 0.620
C49.1 Connective and soft tissue of upper limb, including shoulder
0.619 0.381 0.000
L40.1 Generalised pustular psoriasis
0.000 0.381 0.619
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.382 0.618
M07.5 Arthropathy in ulcerative colitis
0.000 0.382 0.618
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.382 0.618
M07.2 Psoriatic spondylitis
0.000 0.382 0.618
M07.1 Arthritis mutilans
0.000 0.382 0.618
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.382 0.618
M06.3 Rheumatoid nodule
0.000 0.382 0.618
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.618 0.382 0.000
I77.5 Necrosis of artery
0.000 0.382 0.618
I77.4 Coeliac artery compression syndrome
0.000 0.382 0.618
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.382 0.618
E05.8 Other thyrotoxicosis
0.000 0.384 0.615
K75.8 Other specified inflammatory liver diseases
0.000 0.386 0.614
C79.2 Secondary malignant neoplasm of skin
0.614 0.386 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.614 0.386 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.388 0.612
K75.9 Inflammatory liver disease, unspecified
0.000 0.388 0.612
C76.2 Abdomen
0.611 0.389 0.000
G80.0 Spastic cerebral palsy
0.000 0.389 0.611
D63.1 Anaemia in other chronic diseases classified elsewhere
0.000 0.390 0.610
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.390 0.610
D73.9 Disease of spleen, unspecified
0.000 0.390 0.609
E07.1 Dyshormogenetic goitre
0.000 0.390 0.609
E07.0 Hypersecretion of calcitonin
0.000 0.390 0.609
C54 Malignant neoplasm of corpus uteri
0.609 0.391 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.391 0.609
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.392 0.608
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.392 0.608
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.392 0.608
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.392 0.608
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.392 0.608
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.392 0.608
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.392 0.608
K90.9 Intestinal malabsorption, unspecified
0.000 0.393 0.607
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.394 0.606
D81 Combined immunodeficiencies
0.000 0.394 0.606
E22.8 Other hyperfunction of pituitary gland
0.000 0.395 0.605
L43 Lichen planus
0.000 0.396 0.604
E53.9 Vitamin B deficiency, unspecified
0.000 0.397 0.603
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.397 0.603
C85.1 B-cell lymphoma, unspecified
0.602 0.398 0.000
G81.1 Spastic hemiplegia
0.000 0.398 0.602
G21 Secondary Parkinsonism
0.000 0.399 0.601
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.399 0.601
G72.3 Periodic paralysis
0.000 0.399 0.601
G72.2 Myopathy due to other toxic agents
0.000 0.399 0.601
G24.8 Other dystonia
0.000 0.401 0.599
M07.6 Other enteropathic arthropathies
0.000 0.401 0.598
L40.0 Psoriasis vulgaris
0.000 0.401 0.598
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.597 0.403 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.403 0.597
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.403 0.597
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.403 0.597
C18.8 Overlapping lesion of colon
0.597 0.403 0.000
C76.8 Overlapping lesion of other and ill-defined sites
0.596 0.404 0.000
C76.7 Other ill-defined sites
0.596 0.404 0.000
C76.5 Lower limb
0.596 0.404 0.000
C76.4 Upper limb
0.596 0.404 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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