TreeWAS – Variant ID: rs4766897

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	1.000	0.000	0.000
I25.1 Atherosclerotic heart disease	1.000	0.000	0.000
Z95.5 Presence of coronary angioplasty implant and graft	1.000	0.000	0.000
I10 Essential (primary) hypertension	1.000	0.000	0.000
I25 Chronic ischaemic heart disease	1.000	0.000	0.000
I21 Acute myocardial infarction	1.000	0.000	0.000
Z95 Presence of cardiac and vascular implants and grafts	1.000	0.000	0.000
I20-I25 Ischaemic heart diseases	1.000	0.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	1.000	0.000	0.000
I10-I15 Hypertensive diseases	1.000	0.000	0.000
I25.8 Other forms of chronic ischaemic heart disease	1.000	0.000	0.000
I25.2 Old myocardial infarction	0.998	0.002	0.000
I20 Angina pectoris	0.997	0.003	0.000
Z95.4 Presence of other heart-valve replacement	0.997	0.003	0.000
I20.9 Angina pectoris, unspecified	0.997	0.003	0.000
Z95.2 Presence of prosthetic heart valve	0.997	0.003	0.000
E10 Insulin-dependent diabetes mellitus	0.997	0.003	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.996	0.004	0.000
Z95.1 Presence of aortocoronary bypass graft	0.993	0.007	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.991	0.009	0.000
E10.5 With peripheral circulatory complications	0.983	0.017	0.000
M06.9 Rheumatoid arthritis, unspecified	0.982	0.018	0.000
E03 Other hypothyroidism	0.978	0.022	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.976	0.024	0.000
I73 Other peripheral vascular diseases	0.967	0.033	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.964	0.036	0.000
M06 Other rheumatoid arthritis	0.964	0.036	0.000
I73.9 Peripheral vascular disease, unspecified	0.961	0.039	0.000
E10-E14 Diabetes mellitus	0.960	0.040	0.000
E00-E07 Disorders of thyroid gland	0.959	0.041	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.953	0.047	0.000
E10.4 With neurological complications	0.944	0.056	0.000
E10.9 Without complications	0.939	0.061	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.938	0.062	0.000
E10.1 With ketoacidosis	0.936	0.064	0.000
M05-M14 Inflammatory polyarthropathies	0.935	0.065	0.000
I25.5 Ischaemic cardiomyopathy	0.925	0.075	0.000
M05 Seropositive rheumatoid arthritis	0.923	0.077	0.000
Z95.3 Presence of xenogenic heart valve	0.922	0.078	0.000
I22 Subsequent myocardial infarction	0.921	0.079	0.000
I71 Aortic aneurysm and dissection	0.918	0.082	0.000
M07 Psoriatic and enteropathic arthropathies	0.918	0.082	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.915	0.085	0.000
E10.3 With ophthalmic complications	0.914	0.086	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.912	0.088	0.000
M07.3 Other psoriatic arthropathies	0.907	0.093	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.906	0.094	0.000
M06.4 Inflammatory polyarthropathy	0.886	0.114	0.000
E10.0 With coma	0.885	0.115	0.000
C77.3 Axillary and upper limb lymph nodes	0.000	0.117	0.883
I05-I09 Chronic rheumatic heart diseases	0.881	0.119	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.877	0.123	0.000
I74 Arterial embolism and thrombosis	0.873	0.127	0.000
E10.2 With renal complications	0.870	0.130	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.866	0.134	0.000
I12 Hypertensive renal disease	0.864	0.136	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.857	0.143	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.849	0.151	0.000
I23 Certain current complications following acute myocardial infarction	0.844	0.156	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.833	0.167	0.000
E20-E35 Disorders of other endocrine glands	0.833	0.167	0.000
I77 Other disorders of arteries and arterioles	0.832	0.168	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.825	0.175	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.825	0.175	0.000
E10.8 With unspecified complications	0.822	0.178	0.000
I70 Atherosclerosis	0.817	0.183	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.815	0.185	0.000
I25.4 Coronary artery aneurysm	0.812	0.188	0.000
I05 Rheumatic mitral valve diseases	0.809	0.191	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.785	0.215	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.780	0.220	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.777	0.223	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.771	0.229	0.000
I25.6 Silent myocardial ischaemia	0.767	0.233	0.000
E27 Other disorders of adrenal gland	0.767	0.233	0.000
I15 Secondary hypertension	0.760	0.239	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.760	0.240	0.000
E10.6 With other specified complications	0.758	0.242	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.758	0.242	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.755	0.245	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.754	0.246	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.751	0.249	0.000
I12.9 Hypertensive renal disease without renal failure	0.750	0.250	0.000
E03.1 Congenital hypothyroidism without goitre	0.749	0.251	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.744	0.256	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.744	0.256	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.741	0.259	0.000
E03.8 Other specified hypothyroidism	0.740	0.260	0.000
I77.6 Arteritis, unspecified	0.740	0.260	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.738	0.262	0.000
I08 Multiple valve diseases	0.738	0.262	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.736	0.264	0.000
I21.4 Acute subendocardial myocardial infarction	0.736	0.264	0.000
E16 Other disorders of pancreatic internal secretion	0.734	0.266	0.000
I23.8 Other current complications following acute myocardial infarction	0.732	0.268	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.730	0.270	0.000
M05.1 Rheumatoid lung disease	0.730	0.270	0.000
E06 Thyroiditis	0.724	0.276	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.720	0.280	0.000
E27.1 Primary adrenocortical insufficiency	0.720	0.280	0.000
I73.8 Other specified peripheral vascular diseases	0.720	0.280	0.000
I05.0 Mitral stenosis	0.718	0.282	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.718	0.282	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.717	0.283	0.000
M06.8 Other specified rheumatoid arthritis	0.717	0.283	0.000
I13 Hypertensive heart and renal disease	0.717	0.283	0.000
I25.3 Aneurysm of heart	0.714	0.286	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.713	0.287	0.000
M08 Juvenile arthritis	0.713	0.287	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.712	0.288	0.000
E14 Unspecified diabetes mellitus	0.711	0.289	0.000
I05.2 Mitral stenosis with insufficiency	0.704	0.296	0.000
E03.5 Myxoedema coma	0.701	0.298	0.000
E03.4 Atrophy of thyroid (acquired)	0.701	0.298	0.000
E03.3 Postinfectious hypothyroidism	0.701	0.298	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.701	0.298	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.700	0.300	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.699	0.301	0.000
I20.8 Other forms of angina pectoris	0.696	0.304	0.000
M06.3 Rheumatoid nodule	0.695	0.305	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.693	0.307	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.693	0.307	0.000
M06.2 Rheumatoid bursitis	0.691	0.309	0.000
M06.1 Adult-onset Still's disease	0.691	0.309	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.690	0.310	0.000
E16.2 Hypoglycaemia, unspecified	0.689	0.311	0.000
E12 Malnutrition-related diabetes mellitus	0.688	0.312	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.688	0.312	0.000
E00 Congenital iodine-deficiency syndrome	0.688	0.312	0.000
I20.1 Angina pectoris with documented spasm	0.687	0.313	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.687	0.313	0.000
M12 Other specific arthropathies	0.686	0.314	0.000
M07.38 Other psoriatic arthropathies (Other)	0.683	0.317	0.000
E10.7 With multiple complications	0.681	0.319	0.000
M05.8 Other seropositive rheumatoid arthritis	0.680	0.320	0.000
I05.1 Rheumatic mitral insufficiency	0.677	0.323	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.672	0.328	0.000
I77.2 Rupture of artery	0.671	0.328	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.671	0.329	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.670	0.330	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.668	0.332	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.665	0.335	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.663	0.337	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.662	0.338	0.000
M05.2 Rheumatoid vasculitis	0.662	0.338	0.000
M05.0 Felty's syndrome	0.662	0.338	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.658	0.342	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.658	0.342	0.000
M07.5 Arthropathy in ulcerative colitis	0.658	0.342	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.658	0.342	0.000
M07.2 Psoriatic spondylitis	0.658	0.342	0.000
M07.1 Arthritis mutilans	0.658	0.342	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.658	0.342	0.000
E25 Adrenogenital disorders	0.655	0.344	0.000
E27.2 Addisonian crisis	0.654	0.346	0.000
I12.0 Hypertensive renal disease with renal failure	0.654	0.346	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.654	0.346	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.654	0.346	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.650	0.349	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.650	0.349	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.650	0.349	0.000
I00-I02 Acute rheumatic fever	0.650	0.350	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.649	0.351	0.000
I08.0 Disorders of both mitral and aortic valves	0.649	0.351	0.000
E23 Hypofunction and other disorders of pituitary gland	0.644	0.356	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.639	0.361	0.000
I81 Portal vein thrombosis	0.637	0.363	0.000
M07.6 Other enteropathic arthropathies	0.635	0.364	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.635	0.364	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.635	0.364	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.635	0.364	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.635	0.364	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.635	0.364	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.635	0.364	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.635	0.364	0.000
I77.0 Arteriovenous fistula, acquired	0.630	0.370	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.625	0.375	0.000
E34 Other endocrine disorders	0.620	0.380	0.000
I74.5 Embolism and thrombosis of iliac artery	0.620	0.380	0.000
E20 Hypoparathyroidism	0.618	0.382	0.000
I22.8 Subsequent myocardial infarction of other sites	0.617	0.383	0.000
E13 Other specified diabetes mellitus	0.617	0.383	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.615	0.385	0.000
E05.9 Thyrotoxicosis, unspecified	0.615	0.385	0.000
I85 Oesophageal varices	0.613	0.387	0.000
I99 Other and unspecified disorders of circulatory system	0.612	0.388	0.000
E31 Polyglandular dysfunction	0.611	0.389	0.000
E22 Hyperfunction of pituitary gland	0.611	0.389	0.000
E26 Hyperaldosteronism	0.609	0.391	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.609	0.391	0.000
I06 Rheumatic aortic valve diseases	0.607	0.393	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.605	0.395	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.605	0.395	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.605	0.395	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.605	0.395	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.605	0.395	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.605	0.395	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.605	0.395	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.605	0.395	0.000
E40-E46 Malnutrition	0.604	0.396	0.000
I70.9 Generalised and unspecified atherosclerosis	0.604	0.396	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.604	0.396	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.601	0.399	0.000
I77.1 Stricture of artery	0.601	0.399	0.000
I15.1 Hypertension secondary to other renal disorders	0.601	0.399	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.600	0.400	0.000
E07 Other disorders of thyroid	0.599	0.401	0.000
I35 Nonrheumatic aortic valve disorders	0.599	0.401	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.597	0.403	0.000
E32 Diseases of thymus	0.597	0.403	0.000
E30 Disorders of puberty, not elsewhere classified	0.597	0.403	0.000
I77.5 Necrosis of artery	0.596	0.404	0.000
I77.4 Coeliac artery compression syndrome	0.596	0.404	0.000
I77.3 Arterial fibromuscular dysplasia	0.596	0.404	0.000
I85.0 Oesophageal varices with bleeding	0.594	0.406	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.592	0.407	0.000
E15 Nondiabetic hypoglycaemic coma	0.592	0.408	0.000
M05.19 Rheumatoid lung disease (Site unspecified)	0.591	0.409	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.591	0.409	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.589	0.411	0.000
I71.0 Dissection of aorta [any part]	0.588	0.412	0.000
I30-I52 Other forms of heart disease	0.586	0.414	0.000
E27.9 Disorder of adrenal gland, unspecified	0.583	0.417	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.583	0.417	0.000
I78 Diseases of capillaries	0.581	0.418	0.000
I77.8 Other specified disorders of arteries and arterioles	0.581	0.419	0.000
I05.8 Other mitral valve diseases	0.580	0.420	0.000
I70.1 Atherosclerosis of renal artery	0.579	0.421	0.000
E14.4 With neurological complications	0.575	0.424	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.575	0.425	0.000
I08.9 Multiple valve disease, unspecified	0.575	0.425	0.000
I35.1 Aortic (valve) insufficiency	0.574	0.426	0.000
E06.5 Other chronic thyroiditis	0.572	0.428	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.570	0.430	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.569	0.431	0.000
E14.8 With unspecified complications	0.569	0.431	0.000
I70.8 Atherosclerosis of other arteries	0.568	0.431	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.568	0.432	0.000
I07 Rheumatic tricuspid valve diseases	0.566	0.434	0.000
I72 Other aneurysm	0.566	0.434	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.565	0.435	0.000
I87 Other disorders of veins	0.562	0.438	0.000
E14.3 With ophthalmic complications	0.559	0.441	0.000
I15.0 Renovascular hypertension	0.558	0.442	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.556	0.444	0.000
E06.1 Subacute thyroiditis	0.555	0.445	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.555	0.445	0.000
M08.0 Juvenile rheumatoid arthritis	0.554	0.446	0.000
E14.6 With other specified complications	0.553	0.447	0.000
E23.2 Diabetes insipidus	0.553	0.447	0.000
I86 Varicose veins of other sites	0.550	0.450	0.000
E27.5 Adrenomedullary hyperfunction	0.550	0.450	0.000
E27.0 Other adrenocortical overactivity	0.550	0.450	0.000
Z95.0 Presence of cardiac pacemaker	0.549	0.451	0.000
I15.8 Other secondary hypertension	0.545	0.455	0.000
I15.2 Hypertension secondary to endocrine disorders	0.545	0.455	0.000
E27.8 Other specified disorders of adrenal gland	0.545	0.455	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.544	0.456	0.000
I79.1 Aortitis in diseases classified elsewhere	0.541	0.458	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.541	0.458	0.000
E06.9 Thyroiditis, unspecified	0.541	0.459	0.000
I35.0 Aortic (valve) stenosis	0.541	0.459	0.000
E22.1 Hyperprolactinaemia	0.540	0.460	0.000
M06.33 Rheumatoid nodule (Forearm)	0.536	0.463	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.535	0.465	0.000
M11 Other crystal arthropathies	0.534	0.465	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.533	0.467	0.000
E14.2 Withrenal complications	0.533	0.467	0.000
E29 Testicular dysfunction	0.531	0.468	0.000
I88 Nonspecific lymphadenitis	0.531	0.468	0.000
I78.8 Other diseases of capillaries	0.531	0.469	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.528	0.472	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.526	0.474	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.526	0.474	0.000
E16.4 Abnormal secretion of gastrin	0.526	0.474	0.000
E16.3 Increased secretion of glucagon	0.526	0.474	0.000
I87.8 Other specified disorders of veins	0.525	0.475	0.000
I36 Nonrheumatic tricuspid valve disorders	0.525	0.475	0.000
M10 Gout	0.524	0.476	0.000
E14.5 With peripheral circulatory complications	0.524	0.476	0.000
M05.18 Rheumatoid lung disease (Other)	0.523	0.477	0.000
M05.17 Rheumatoid lung disease (Ankle and foot)	0.523	0.477	0.000
M05.16 Rheumatoid lung disease (Lower leg)	0.523	0.477	0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.523	0.477	0.000
M05.14 Rheumatoid lung disease (Hand)	0.523	0.477	0.000
M05.13 Rheumatoid lung disease (Forearm)	0.523	0.477	0.000
M05.12 Rheumatoid lung disease (Upper arm)	0.523	0.477	0.000
M05.11 Rheumatoid lung disease (Shoulder region)	0.523	0.477	0.000
M05.10 Rheumatoid lung disease (Multiple sites)	0.523	0.477	0.000
E06.4 Drug-induced thyroiditis	0.519	0.481	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.519	0.481	0.000
E06.0 Acute thyroiditis	0.519	0.481	0.000
M12.8 Other specific arthropathies, not elsewhere classified	0.518	0.482	0.000
E16.1 Other hypoglycaemia	0.518	0.482	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.517	0.483	0.000
I09 Other rheumatic heart diseases	0.515	0.484	0.000
I15.9 Seconday hypertension, unspecified	0.515	0.485	0.000
E28 Ovarian dysfunction	0.515	0.485	0.000
M06.88 Other specified rheumatoid arthritis (Other)	0.514	0.486	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.514	0.486	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.514	0.486	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.514	0.486	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.514	0.486	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.514	0.486	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.514	0.486	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.514	0.486	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.514	0.486	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.514	0.486	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.514	0.486	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.514	0.486	0.000
E05.5 Thyroid crisis or storm	0.511	0.489	0.000
E05.4 Thyrotoxicosis factitia	0.511	0.489	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.511	0.489	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.511	0.489	0.000
M08.9 Juvenile arthritis, unspecified	0.511	0.489	0.000
M08.8 Other juvenile arthritis	0.511	0.489	0.000
M08.4 Pauciarticular juvenile arthritis	0.511	0.489	0.000
M08.3 Juvenile polyarthritis (seronegative)	0.511	0.489	0.000
M08.2 Juvenile arthritis with systemic onset	0.511	0.489	0.000
M08.1 Juvenile ankylosing spondylitis	0.511	0.489	0.000
I21.9 Acute myocardial infarction, unspecified	0.511	0.489	0.000
E14.7 With multiple complications	0.510	0.490	0.000
E14.0 With coma	0.510	0.490	0.000
I74.8 Embolism and thrombosis of other arteries	0.508	0.492	0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.506	0.494	0.000
I50 Heart failure	0.505	0.495	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.504	0.496	0.000
M14 Arthropathies in other diseases classified elsewhere	0.500	0.499	0.000
M12.5 Traumatic arthropathy	0.499	0.500	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.498	0.502	0.000
M06.38 Rheumatoid nodule (Other)	0.498	0.502	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.498	0.502	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.498	0.502	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.498	0.502	0.000
I86.4 Gastric varices	0.497	0.503	0.000
I37 Pulmonary valve disorders	0.497	0.503	0.000
E50-E64 Other nutritional deficiencies	0.497	0.503	0.000
M06.19 Adult-onset Still's disease (Site unspecified)	0.495	0.504	0.000
M06.18 Adult-onset Still's disease (Other)	0.495	0.504	0.000
M06.17 Adult-onset Still's disease (Ankle and foot)	0.495	0.504	0.000
M06.16 Adult-onset Still's disease (Lower leg)	0.495	0.504	0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.495	0.504	0.000
M06.14 Adult-onset Still's disease (Hand)	0.495	0.504	0.000
M06.13 Adult-onset Still's disease (Forearm)	0.495	0.504	0.000
M06.12 Adult-onset Still's disease (Upper arm)	0.495	0.504	0.000
M06.11 Adult-onset Still's disease (Shoulder region)	0.495	0.504	0.000
M06.10 Adult-onset Still's disease (Multiple sites)	0.495	0.504	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.495	0.504	0.000
M06.28 Rheumatoid bursitis (Other)	0.495	0.504	0.000
M06.27 Rheumatoid bursitis (Ankle and foot)	0.495	0.504	0.000
M06.26 Rheumatoid bursitis (Lower leg)	0.495	0.504	0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.495	0.504	0.000
M06.24 Rheumatoid bursitis (Hand)	0.495	0.504	0.000
M06.23 Rheumatoid bursitis (Forearm)	0.495	0.504	0.000
M06.22 Rheumatoid bursitis (Upper arm)	0.495	0.504	0.000
M06.21 Rheumatoid bursitis (Shoulder region)	0.495	0.504	0.000
M06.20 Rheumatoid bursitis (Multiple sites)	0.495	0.504	0.000
I45 Other conduction disorders	0.495	0.505	0.000
M12.2 Villonodular synovitis (pigmented)	0.494	0.506	0.000
E12.9 Without complications	0.493	0.506	0.000
E12.8 With unspecified complications	0.493	0.506	0.000
E12.7 With multiple complications	0.493	0.506	0.000
E12.6 With other specified complications	0.493	0.506	0.000
E12.5 With peripheral circulatory complications	0.493	0.506	0.000
E12.4 With neurological complications	0.493	0.506	0.000
E12.3 With ophthalmic complications	0.493	0.506	0.000
E12.2 With renal complications	0.493	0.506	0.000
E12.1 With ketoacidosis	0.493	0.506	0.000
E12.0 With coma	0.493	0.506	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.493	0.507	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.493	0.507	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.493	0.507	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.493	0.507	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.493	0.507	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.493	0.507	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.493	0.507	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.493	0.507	0.000
M12.4 Intermittent hydrarthrosis	0.492	0.508	0.000
M12.1 Kaschin-Beck disease	0.492	0.508	0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.492	0.508	0.000
M06.0 Seronegative rheumatoid arthritis	0.491	0.509	0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.488	0.512	0.000
M05.88 Other seropositive rheumatoid arthritis (Other)	0.488	0.512	0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.488	0.512	0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.488	0.512	0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.488	0.512	0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.488	0.512	0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.488	0.512	0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.488	0.512	0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.488	0.512	0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.481	0.519	0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.480	0.519	0.000
M09.2 Juvenile arthritis in ulcerative colitis	0.480	0.519	0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.480	0.519	0.000
M09.0 Juvenile arthritis in psoriasis	0.480	0.519	0.000
M05.09 Felty's syndrome (Site unspecified)	0.475	0.525	0.000
M05.08 Felty's syndrome (Other)	0.475	0.525	0.000
M05.07 Felty's syndrome (Ankle and foot)	0.475	0.525	0.000
M05.06 Felty's syndrome (Lower leg)	0.475	0.525	0.000
M05.05 Felty's syndrome (Pelvic region and thigh)	0.475	0.525	0.000
M05.04 Felty's syndrome (Hand)	0.475	0.525	0.000
M05.03 Felty's syndrome (Forearm)	0.475	0.525	0.000
M05.02 Felty's syndrome (Upper arm)	0.475	0.525	0.000
M05.01 Felty's syndrome (Shoulder region)	0.475	0.525	0.000
M05.00 Felty's syndrome (Multiple sites)	0.475	0.525	0.000
M05.29 Rheumatoid vasculitis (Site unspecified)	0.475	0.525	0.000
M05.28 Rheumatoid vasculitis (Other)	0.475	0.525	0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.475	0.525	0.000
M05.26 Rheumatoid vasculitis (Lower leg)	0.475	0.525	0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.475	0.525	0.000
M05.24 Rheumatoid vasculitis (Hand)	0.475	0.525	0.000
M05.23 Rheumatoid vasculitis (Forearm)	0.475	0.525	0.000
M05.22 Rheumatoid vasculitis (Upper arm)	0.475	0.525	0.000
M05.21 Rheumatoid vasculitis (Shoulder region)	0.475	0.525	0.000
M05.20 Rheumatoid vasculitis (Multiple sites)	0.475	0.525	0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.475	0.525	0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.475	0.525	0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.475	0.525	0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.475	0.525	0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.475	0.525	0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.475	0.525	0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.475	0.525	0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.475	0.525	0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.475	0.525	0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.475	0.525	0.000
E23.0 Hypopituitarism	0.475	0.525	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.474	0.526	0.000
I50.0 Congestive heart failure	0.472	0.528	0.000
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)	0.472	0.528	0.000
M07.08 Distal interphalangeal proriatic arthropathy-Other	0.472	0.528	0.000
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)	0.472	0.528	0.000
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg	0.472	0.528	0.000
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh	0.472	0.528	0.000
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)	0.472	0.528	0.000
M07.03 Distal interphalangeal proriatic arthropathy-Forearm	0.472	0.528	0.000
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm	0.472	0.528	0.000
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region	0.472	0.528	0.000
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)	0.472	0.528	0.000
M07.19 Arthritis mutilans (Site unspecified)	0.472	0.528	0.000
M07.18 Arthritis mutilans (Other)	0.472	0.528	0.000
M07.17 Arthritis mutilans (Ankle and foot)	0.472	0.528	0.000
M07.16 Arthritis mutilans (Lower leg)	0.472	0.528	0.000
M07.15 Arthritis mutilans (Pelvic region and thigh)	0.472	0.528	0.000
M07.14 Arthritis mutilans (Hand)	0.472	0.528	0.000
M07.13 Arthritis mutilans (Forearm)	0.472	0.528	0.000
M07.12 Arthritis mutilans (Upper arm)	0.472	0.528	0.000
M07.11 Arthritis mutilans (Shoulder region)	0.472	0.528	0.000
M07.10 Arthritis mutilans (Multiple sites)	0.472	0.528	0.000
M07.29 Psoriatic spondylitis (Site unspecified)	0.472	0.528	0.000
M07.28 Psoriatic spondylitis (Other)	0.472	0.528	0.000
M07.27 Psoriatic spondylitis (Ankle and foot)	0.472	0.528	0.000
M07.26 Psoriatic spondylitis (Lower leg)	0.472	0.528	0.000
M07.25 Psoriatic spondylitis (Pelvic region and thigh)	0.472	0.528	0.000
M07.24 Psoriatic spondylitis (Hand)	0.472	0.528	0.000
M07.23 Psoriatic spondylitis (Forearm)	0.472	0.528	0.000
M07.22 Psoriatic spondylitis (Upper arm)	0.472	0.528	0.000
M07.21 Psoriatic spondylitis (Shoulder region)	0.472	0.528	0.000
M07.20 Psoriatic spondylitis (Multiple sites)	0.472	0.528	0.000
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)	0.472	0.528	0.000
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)	0.472	0.528	0.000
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)	0.472	0.528	0.000
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)	0.472	0.528	0.000
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)	0.472	0.528	0.000
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)	0.472	0.528	0.000
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)	0.472	0.528	0.000
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)	0.472	0.528	0.000
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)	0.472	0.528	0.000
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)	0.472	0.528	0.000
M07.59 Arthropathy in ulcerative colitis (Site unspecified)	0.472	0.528	0.000
M07.58 Arthropathy in ulcerative colitis (Other)	0.472	0.528	0.000
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)	0.472	0.528	0.000
M07.56 Arthropathy in ulcerative colitis (Lower leg)	0.472	0.528	0.000
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)	0.472	0.528	0.000
M07.54 Arthropathy in ulcerative colitis (Hand)	0.472	0.528	0.000
M07.53 Arthropathy in ulcerative colitis (Forearm)	0.472	0.528	0.000
M07.52 Arthropathy in ulcerative colitis (Upper arm)	0.472	0.528	0.000
M07.51 Arthropathy in ulcerative colitis (Shoulder region)	0.472	0.528	0.000
M07.50 Arthropathy in ulcerative colitis (Multiple sites)	0.472	0.528	0.000
E25.9 Adrenogenital disorder, unspecified	0.470	0.530	0.000
E25.8 Other adrenogenital disorders	0.470	0.530	0.000
M12.3 Palindromic rheumatism	0.469	0.530	0.000
E13.3 With ophthalmic complications	0.467	0.533	0.000
I02 Rheumatic chorea	0.466	0.534	0.000
I01 Rheumatic fever with heart involvement	0.466	0.534	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.464	0.536	0.000
E20.9 Hypoparathyroidism, unspecified	0.464	0.536	0.000
M06.34 Rheumatoid nodule (Hand)	0.463	0.537	0.000
E14.1 With ketoacidosis	0.463	0.537	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.462	0.538	0.000
E23.1 Drug-induced hypopituitarism	0.462	0.538	0.000
E24 Cushing's syndrome	0.462	0.538	0.000
I72.2 Aneurysm of renal artery	0.461	0.539	0.000
E26.9 Hyperaldosteronism, unspecified	0.459	0.541	0.000
E07.9 Disorder of thyroid, unspecified	0.458	0.542	0.000
E34.8 Other specified endocrine disorders	0.457	0.543	0.000
I33 Acute and subacute endocarditis	0.456	0.544	0.000
M07.68 Other enteropathic arthropathies (Other)	0.456	0.544	0.000
M07.67 Other enteropathic arthropathies (Ankle and foot)	0.456	0.544	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations