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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant cluster associations

Hospitalization Episode Statistics (HES)

Cluster X0060
log Bayes Factor = 242.413
contains 5 variants:
rs61772626
lBF = 10.160
Chr 1 : 57,015,668
rs11678166
lBF = 11.292
Chr 2 : 61,157,720
rs79299247
lBF = 13.726
Chr 9 : 82,970,155
rs80213544
lBF = 10.505
Chr16 : 75,116,252
rs4420638
lBF =199.322
Chr19 : 45,422,946
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E78.0 Pure hypercholesterolaemia
1.000 0.000 0.000
E78.5 Hyperlipidaemia, unspecified
1.000 0.000 0.000
F00.9 Dementia in Alzheimer's disease, unspecified
1.000 0.000 0.000
F01.9 Vascular dementia, unspecified
1.000 0.000 0.000
F03 Unspecified dementia
1.000 0.000 0.000
G30.9 Alzheimer's disease, unspecified
1.000 0.000 0.000
I20.0 Unstable angina
1.000 0.000 0.000
I20.9 Angina pectoris, unspecified
1.000 0.000 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
1.000 0.000 0.000
I25.1 Atherosclerotic heart disease
1.000 0.000 0.000
I25.2 Old myocardial infarction
1.000 0.000 0.000
I25.8 Other forms of chronic ischaemic heart disease
1.000 0.000 0.000
I25.9 Chronic ischaemic heart disease, unspecified
1.000 0.000 0.000
R41.0 Disorientation, unspecified
1.000 0.000 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
1.000 0.000 0.000
Z95.1 Presence of aortocoronary bypass graft
1.000 0.000 0.000
Z95.5 Presence of coronary angioplasty implant and graft
1.000 0.000 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
1.000 0.000 0.000
F00 Dementia in Alzheimer's disease
1.000 0.000 0.000
G30 Alzheimer's disease
1.000 0.000 0.000
I20 Angina pectoris
1.000 0.000 0.000
I21 Acute myocardial infarction
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
Z95 Presence of cardiac and vascular implants and grafts
1.000 0.000 0.000
F00-F09 Organic, including symptomatic, mental disorders
1.000 0.000 0.000
G30-G32 Other degenerative diseases of the nervous system
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
I60-I69 Cerebrovascular diseases
1.000 0.000 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
1.000 0.000 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
F01 Vascular dementia
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
Z95.0 Presence of cardiac pacemaker
1.000 0.000 0.000
I05-I09 Chronic rheumatic heart diseases
1.000 0.000 0.000
I67 Other cerebrovascular diseases
1.000 0.000 0.000
I08 Multiple valve diseases
0.999 0.001 0.000
F05.9 Delirium, unspecified
0.998 0.002 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.997 0.003 0.000
V40-V49 Car occupant injured in transport accident
0.996 0.004 0.000
Y52 Agents primarily affecting the cardiovascular system
0.996 0.004 0.000
I61 Intracerebral haemorrhage
0.995 0.005 0.000
I20.8 Other forms of angina pectoris
0.994 0.006 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.993 0.007 0.000
F02 Dementia in other diseases classified elsewhere
0.993 0.007 0.000
V49 Car occupant injured in other and unspecified transport accidents
0.991 0.009 0.000
I21.9 Acute myocardial infarction, unspecified
0.991 0.009 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.991 0.009 0.000
G30.0 Alzheimer's disease with early onset
0.990 0.010 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.989 0.011 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.989 0.011 0.000
I71 Aortic aneurysm and dissection
0.988 0.012 0.000
I22 Subsequent myocardial infarction
0.987 0.013 0.000
Y43 Primarily systemic agents
0.986 0.014 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.985 0.015 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.984 0.016 0.000
M86-M90 Other osteopathies
0.984 0.016 0.000
V49.9 Car occupant [any] injured in unspecified traffic accident
0.983 0.017 0.000
I67.9 Cerebrovascular disease, unspecified
0.981 0.019 0.000
Chapter XXII Codes for special purposes
0.979 0.021 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.978 0.022 0.000
E78.4 Other hyperlipidaemia
0.977 0.023 0.000
M80-M85 Disorders of bone density and structure
0.976 0.024 0.000
I72 Other aneurysm
0.975 0.025 0.000
F00.2 Dementia in Alzheimer's disease, atypical or mixed type
0.975 0.025 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.975 0.025 0.000
F05.0 Delirium not superimposed on dementia, so described
0.974 0.026 0.000
F00.0 Dementia in Alzheimer's disease with early onset
0.973 0.027 0.000
Y84.0 Cardiac catheterisation
0.973 0.027 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.972 0.028 0.000
I65.2 Occlusion and stenosis of carotid artery
0.972 0.028 0.000
E70-E90 Metabolic disorders
0.971 0.029 0.000
I69 Sequelae of cerebrovascular disease
0.970 0.030 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.970 0.030 0.000
I08.0 Disorders of both mitral and aortic valves
0.968 0.032 0.000
M85 Other disorders of bone density and structure
0.967 0.033 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.967 0.033 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.965 0.035 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.965 0.035 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.965 0.035 0.000
G30.8 Other Alzheimer's disease
0.964 0.036 0.000
M60-M63 Disorders of muscles
0.957 0.043 0.000
Y43.3 Other antineoplastic drugs
0.957 0.043 0.000
I08.8 Other multiple valve diseases
0.956 0.044 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.956 0.044 0.000
F02.3 Dementia in Parkinson's disease
0.956 0.044 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.954 0.046 0.000
I21.4 Acute subendocardial myocardial infarction
0.952 0.048 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.949 0.051 0.000
I62 Other nontraumatic intracranial haemorrhage
0.949 0.051 0.000
I67.1 Cerebral aneurysm, nonruptured
0.948 0.052 0.000
G31.8 Other specified degenerative diseases of nervous system
0.946 0.054 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.946 0.054 0.000
R45 Symptoms and signs involving emotional state
0.943 0.057 0.000
M87 Osteonecrosis
0.941 0.059 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.940 0.060 0.000
R45.1 Restlessness and agitation
0.939 0.061 0.000
I67.2 Cerebral atherosclerosis
0.939 0.061 0.000
E78.2 Mixed hyperlipidaemia
0.938 0.062 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.938 0.062 0.000
I70 Atherosclerosis
0.937 0.063 0.000
M85.0 Fibrous dysplasia (monostotic)
0.937 0.063 0.000
F02.8 Dementia in other specified diseases classified elsewhere
0.931 0.069 0.000
U51 Admission status on psychiatric patients
0.929 0.071 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.929 0.071 0.000
I72.4 Aneurysm of artery of lower extremity
0.928 0.072 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.927 0.073 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.927 0.073 0.000
G20-G26 Extrapyramidal and movement disorders
0.926 0.074 0.000
F23 Acute and transient psychotic disorders
0.925 0.075 0.000
I61.4 Intracerebral haemorrhage in cerebellum
0.925 0.075 0.000
I25.5 Ischaemic cardiomyopathy
0.924 0.076 0.000
F05.8 Other delirium
0.919 0.081 0.000
I71.0 Dissection of aorta [any part]
0.918 0.082 0.000
E85 Amyloidosis
0.917 0.083 0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)
0.916 0.084 0.000
M85.6 Other cyst of bone
0.915 0.085 0.000
M62 Other disorders of muscle
0.914 0.086 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.913 0.087 0.000
I06 Rheumatic aortic valve diseases
0.913 0.087 0.000
E78.8 Other disorders of lipoprotein metabolism
0.911 0.089 0.000
Q50-Q56 Congenital malformations of genital organs
0.910 0.090 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.905 0.095 0.000
I60 Subarachnoid haemorrhage
0.902 0.098 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.902 0.098 0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.902 0.098 0.000
Q66 Congenital deformities of feet
0.901 0.099 0.000
Y43.0 Antiallergic and antiemetic drugs
0.901 0.099 0.000
G30.1 Alzheimer's disease with late onset
0.899 0.101 0.000
F05.1 Delirium superimposed on dementia
0.898 0.102 0.000
V20-V29 Motorcycle rider injured in transport accident
0.898 0.102 0.000
F23.9 Acute and transient psychotic disorder, unspecified
0.893 0.107 0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.893 0.107 0.000
M88 Paget's disease of bone [osteitis deformans]
0.892 0.108 0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.891 0.109 0.000
Q79.6 Ehlers-Danlos syndrome
0.891 0.109 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.886 0.114 0.000
Y48 Anaesthetics and therapeutic gases
0.886 0.114 0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.885 0.115 0.000
I05 Rheumatic mitral valve diseases
0.885 0.115 0.000
I72.0 Aneurysm of carotid artery
0.883 0.117 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.883 0.117 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.878 0.122 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.875 0.125 0.000
F25 Schizoaffective disorders
0.874 0.126 0.000
U51.0 Not Previously admitted to a psyciatric hospital
0.874 0.126 0.000
I23 Certain current complications following acute myocardial infarction
0.874 0.126 0.000
W75-W84 Other accidental threats to breathing
0.872 0.128 0.000
E87.0 Hyperosmolality and hypernatraemia
0.870 0.130 0.000
Y00-Y09 Assault
0.869 0.131 0.000
I67.8 Other specified cerebrovascular diseases
0.868 0.132 0.000
V01-V09 Pedestrian injured in transport accident
0.865 0.135 0.000
F00.1 Dementia in Alzheimer's disease with late onset
0.865 0.135 0.000
M87.2 Osteonecrosis due to previous trauma
0.864 0.136 0.000
Y43.1 Antineoplastic antimetabolites
0.864 0.136 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.862 0.138 0.000
M85.65 Other cyst of bone (Pelvic region and thigh)
0.858 0.142 0.000
G52 Disorders of other cranial nerves
0.857 0.143 0.000
U80 Agent resistant to penicillin and related antibiotics
0.856 0.144 0.000
F60-F69 Disorders of adult personality and behaviour
0.851 0.149 0.000
Q53 Undescended testicle
0.851 0.149 0.000
M84 Disorders of continuity of bone
0.848 0.152 0.000
G54 Nerve root and plexus disorders
0.848 0.152 0.000
I61.3 Intracerebral haemorrhage in brain stem
0.846 0.154 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.844 0.156 0.000
M00-M03 Infectious arthropathies
0.838 0.162 0.000
F01.1 Multi-infarct dementia
0.838 0.162 0.000
X20-X29 Contact with venomous animals and plants
0.838 0.162 0.000
I05.1 Rheumatic mitral insufficiency
0.836 0.164 0.000
I60.4 Subarachnoid haemorrhage from basilar artery
0.836 0.164 0.000
M40-M43 Deforming dorsopathies
0.836 0.164 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.835 0.165 0.000
Y42.7 Androgens and anabolic congeners
0.834 0.166 0.000
G51 Facial nerve disorders
0.834 0.166 0.000
M87.9 Osteonecrosis, unspecified
0.833 0.167 0.000
M62.8 Other specified disorders of muscle
0.833 0.167 0.000
Q74 Other congenital malformations of limb(s)
0.832 0.168 0.000
V48 Car occupant injured in noncollision transport accident
0.832 0.168 0.000
G57 Mononeuropathies of lower limb
0.829 0.171 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.828 0.172 0.000
M86 Osteomyelitis
0.827 0.173 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.827 0.173 0.000
M88.9 Paget's disease of bone, unspecified
0.826 0.174 0.000
V49.4 Driver injured in collision with other and unspecified motor vehicles in traffic accident
0.826 0.174 0.000
Y59 Other and unspecified vaccines and biological substances
0.824 0.176 0.000
G31.2 Degeneration of nervous system due to alcohol
0.823 0.177 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.823 0.177 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.822 0.178 0.000
Z95.3 Presence of xenogenic heart valve
0.818 0.182 0.000
I20.1 Angina pectoris with documented spasm
0.814 0.186 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.813 0.187 0.000
Y44 Agents primarily affecting blood constituents
0.811 0.189 0.000
E87.3 Alkalosis
0.809 0.191 0.000
F02.0 Dementia in Pick's disease
0.809 0.191 0.000
Q53.1 Undescended testicle, unilateral
0.808 0.192 0.000
U51.1 Previously admitted to a psychiatric hospital of the provider
0.808 0.192 0.000
E85.4 Organ-limited amyloidosis
0.806 0.194 0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.805 0.195 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.804 0.196 0.000
I69.3 Sequelae of cerebral infarction
0.803 0.197 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.802 0.198 0.000
G20 Parkinson's disease
0.802 0.198 0.000
Y04 Assault by bodily force
0.798 0.202 0.000
E85.9 Amyloidosis, unspecified
0.796 0.204 0.000
R45.6 Physical violence
0.795 0.205 0.000
F30-F39 Mood [affective] disorders
0.793 0.207 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.793 0.207 0.000
M90 Osteopathies in diseases classified elsewhere
0.793 0.207 0.000
M60 Myositis
0.792 0.208 0.000
I06.1 Rheumatic aortic insufficiency
0.791 0.209 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.789 0.211 0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics
0.788 0.212 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.788 0.212 0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.785 0.215 0.000
F06.7 Mild cognitive disorder
0.785 0.215 0.000
Y41.0 Sulphonamides
0.784 0.216 0.000
Q66.2 Metatarsus varus
0.783 0.217 0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action
0.783 0.217 0.000
I23.8 Other current complications following acute myocardial infarction
0.783 0.217 0.000
I60.8 Other subarachnoid haemorrhage
0.782 0.218 0.000
I06.0 Rheumatic aortic stenosis
0.781 0.219 0.000
V49.5 Passenger injured in collision with other and unspecified motor vehicles in traffic accident
0.780 0.220 0.000
F29 Unspecified nonorganic psychosis
0.779 0.221 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.779 0.221 0.000
G57.5 Tarsal tunnel syndrome
0.779 0.221 0.000
Q00-Q07 Congenital malformations of the nervous system
0.778 0.222 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.778 0.222 0.000
I72.3 Aneurysm of iliac artery
0.778 0.222 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.777 0.223 0.000
V43 Car occupant injured in collision with car, pick-up truck or van
0.777 0.223 0.000
Y40 Systemic antibiotics
0.776 0.224 0.000
U81 Agent resistant to vancomycin and related antibiotics
0.774 0.226 0.000
G51.0 Bell's palsy
0.774 0.226 0.000
R41.2 Retrograde amnesia
0.773 0.227 0.000
I61.5 Intracerebral haemorrhage, intraventricular
0.773 0.227 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.773 0.227 0.000
V98-V99 Other and unspecified transport accidents
0.770 0.230 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.770 0.230 0.000
V80-V89 Other land transport accidents
0.769 0.231 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.769 0.231 0.000
Q65 Congenital deformities of hip
0.768 0.232 0.000
F80-F89 Disorders of psychological development
0.765 0.235 0.000
Q76 Congenital malformations of spine and bony thorax
0.763 0.237 0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.762 0.238 0.000
V90-V94 Water transport accidents
0.761 0.239 0.000
M85.2 Hyperostosis of skull
0.761 0.239 0.000
G40-G47 Episodic and paroxysmal disorders
0.758 0.242 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.757 0.243 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.757 0.243 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.756 0.243 0.000
X00-X09 Exposure to smoke, fire and flames
0.756 0.244 0.000
M84.8 Other disorders of continuity of bone
0.756 0.244 0.000
U80.1 Methicillin resistant agent
0.756 0.244 0.000
E50-E64 Other nutritional deficiencies
0.756 0.244 0.000
Y42.1 Thyroid hormones and substitutes
0.755 0.245 0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest
0.754 0.246 0.000
Q66.9 Congenital deformity of feet, unspecified
0.753 0.247 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.752 0.248 0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system
0.750 0.250 0.000
M62.6 Muscle strain
0.750 0.250 0.000
M62.82 Other specified disorders of muscle (Upper arm)
0.749 0.251 0.000
M43 Other deforming dorsopathies
0.748 0.252 0.000
Y84.1 Kidney dialysis
0.748 0.252 0.000
F22 Persistent delusional disorders
0.746 0.254 0.000
W78 Inhalation of gastric contents
0.746 0.254 0.000
Y10-Y34 Event of undetermined intent
0.744 0.256 0.000
Y48.2 Other and unspecified general anaesthetics
0.744 0.256 0.000
Y48.4 Anaesthetic, unspecified
0.742 0.258 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.741 0.259 0.000
I72.2 Aneurysm of renal artery
0.741 0.259 0.000
G52.9 Cranial nerve disorder, unspecified
0.740 0.260 0.000
F39 Unspecified mood [affective] disorder
0.739 0.261 0.000
I65.0 Occlusion and stenosis of vertebral artery
0.738 0.262 0.000
G31.0 Circumscribed brain atrophy
0.736 0.264 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.736 0.264 0.000
I05.0 Mitral stenosis
0.735 0.265 0.000
G25 Other extrapyramidal and movement disorders
0.735 0.265 0.000
R45.7 State of emotional shock and stress, unspecified
0.735 0.265 0.000
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)
0.735 0.265 0.000
V95-V97 Air and space transport accidents
0.734 0.265 0.000
X60-X84 Intentional self-harm
0.733 0.267 0.000
I68.0 Cerebral amyloid angiopathy
0.733 0.267 0.000
G23 Other degenerative diseases of basal ganglia
0.732 0.267 0.000
M62.9 Disorder of muscle, unspecified
0.732 0.268 0.000
M91-M94 Chondropathies
0.732 0.268 0.000
M87.96 Osteonecrosis, unspecified (Lower leg)
0.731 0.269 0.000
Q55 Other congenital malformations of male genital organs
0.730 0.270 0.000
M88.99 Paget's disease of bone, unspecified (Site unspecified)
0.729 0.271 0.000
G04.8 Other encephalitis, myelitis and encephalomyelitis
0.728 0.272 0.000
V22 Motorcycle rider injured in collision with two- or three-wheeled motor vehicle
0.728 0.272 0.000
V70-V79 Bus occupant injured in transport accident
0.727 0.273 0.000
G57.0 Lesion of sciatic nerve
0.726 0.274 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.726 0.274 0.000
I08.9 Multiple valve disease, unspecified
0.725 0.275 0.000
R43 Disturbances of smell and taste
0.725 0.275 0.000
M00 Pyogenic arthritis
0.725 0.275 0.000
X50-X57 Overexertion, travel and privation
0.724 0.276 0.000
G54.1 Lumbosacral plexus disorders
0.723 0.277 0.000
M84.4 Pathological fracture, not elsewhere classified
0.723 0.277 0.000
M80 Osteoporosis with pathological fracture
0.723 0.277 0.000
R45.4 Irritability and anger
0.722 0.278 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.722 0.278 0.000
M43.0 Spondylolysis
0.722 0.278 0.000
E74 Other disorders of carbohydrate metabolism
0.722 0.278 0.000
X23 Contact with hornets, wasps and bees
0.722 0.278 0.000
G52.2 Disorders of vagus nerve
0.721 0.279 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.721 0.279 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.720 0.280 0.000
E85.3 Secondary systemic amyloidosis
0.720 0.280 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.720 0.280 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.719 0.280 0.000
R45.5 Hostility
0.719 0.281 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.719 0.281 0.000
G41 Status epilepticus
0.718 0.282 0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.718 0.282 0.000
R46 Symptoms and signs involving appearance and behaviour
0.717 0.283 0.000
E78.3 Hyperchylomicronaemia
0.717 0.283 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.717 0.283 0.000
F09 Unspecified organic or symptomatic mental disorder
0.717 0.283 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.717 0.283 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
F01.0 Vascular dementia of acute onset
0.717 0.283 0.000
F01.2 Subcortical vascular dementia
0.717 0.283 0.000
F01.3 Mixed cortical and subcortical vascular dementia
0.717 0.283 0.000
F01.8 Other vascular dementia
0.717 0.283 0.000
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)
0.717 0.283 0.000
I67.3 Progressive vascular leukoencephalopathy
0.717 0.283 0.000
I67.4 Hypertensive encephalopathy
0.717 0.283 0.000
I67.5 Moyamoya disease
0.717 0.283 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.717 0.283 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.717 0.283 0.000
F60 Specific personality disorders
0.716 0.284 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.716 0.284 0.000
V40 Car occupant injured in collision with pedestrian or animal
0.714 0.286 0.000
V41 Car occupant injured in collision with pedal cycle
0.714 0.286 0.000
V42 Car occupant injured in collision with two- or three-wheeled motor vehicle
0.714 0.286 0.000
V45 Car occupant injured in collision with railway train or railway vehicle
0.714 0.286 0.000
V46 Car occupant injured in collision with other nonmotor vehicle
0.714 0.286 0.000
V47 Car occupant injured in collision with fixed or stationary object
0.714 0.286 0.000
M85.66 Other cyst of bone (Lower leg)
0.714 0.286 0.000
V48.4 Person injured while boarding or alighting
0.714 0.286 0.000
Y52.7 Peripheral vasodilators
0.714 0.286 0.000
Y52.8 Antivaricose drugs, including sclerosing agents
0.714 0.286 0.000
F70-F79 Mental retardation
0.714 0.286 0.000
G54.0 Brachial plexus disorders
0.713 0.287 0.000
F02.1 Dementia in Creutzfeldt-Jakob disease
0.712 0.288 0.000
F02.2 Dementia in Huntington's disease
0.712 0.288 0.000
F02.4 Dementia in human immunodeficiency virus [HIV] disease
0.712 0.288 0.000
G21 Secondary Parkinsonism
0.711 0.289 0.000
V49.0 Driver injured in collision with other and unspecified motor vehicles in nontraffic accident
0.711 0.289 0.000
V49.1 Passenger injured in collision with other and unspecified motor vehicles in nontraffic accident
0.711 0.289 0.000
V49.2 Unspecified car occupant injured in collision with other and unspecified motor vehicles in nontraffic accident
0.711 0.289 0.000
V49.3 Car occupant [any] injured in unspecified nontraffic accident
0.711 0.289 0.000
V49.6 Unspecified car occupant injured in collision with other and unspecified motor vehicles in traffic accident
0.711 0.289 0.000
V49.8 Car occupant [any] injured in other specified transport accidents
0.711 0.289 0.000
Y40.3 Macrolides
0.711 0.289 0.000
Y54.8 Agents affecting uric acid metabolism
0.711 0.289 0.000
G31.1 Senile degeneration of brain, not elsewhere classified
0.710 0.290 0.000
F25.2 Schizoaffective disorder, mixed type
0.709 0.291 0.000
Y04.8 Other specified place
0.709 0.291 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.709 0.291 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.709 0.291 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.709 0.291 0.000
Q74.1 Congenital malformation of knee
0.708 0.292 0.000
I61.6 Intracerebral haemorrhage, multiple localised
0.707 0.293 0.000
Y43.2 Antineoplastic natural products
0.707 0.293 0.000
Y43.5 Acidifying and alkalising agents
0.707 0.293 0.000
Y43.6 Enzymes, not elsewhere classified
0.707 0.293 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.707 0.293 0.000
Y43.9 Primarily systemic agent, unspecified
0.707 0.293 0.000
E78.6 Lipoprotein deficiency
0.706 0.294 0.000
Y58 Bacterial vaccines
0.706 0.294 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.706 0.294 0.000
Q35-Q37 Cleft lip and cleft palate
0.706 0.294 0.000
I65.8 Occlusion and stenosis of other precerebral artery
0.706 0.294 0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.706 0.294 0.000
M87.97 Osteonecrosis, unspecified (Ankle and foot)
0.706 0.294 0.000
W20-W49 Exposure to inanimate mechanical forces
0.705 0.295 0.000
I00-I02 Acute rheumatic fever
0.704 0.296 0.000
I25.4 Coronary artery aneurysm
0.704 0.296 0.000
I09 Other rheumatic heart diseases
0.703 0.297 0.000
Q68 Other congenital musculoskeletal deformities
0.701 0.298 0.000
Q69 Polydactyly
0.701 0.298 0.000
Q70 Syndactyly
0.701 0.298 0.000
Q71 Reduction defects of upper limb
0.701 0.298 0.000
Q72 Reduction defects of lower limb
0.701 0.298 0.000
Q73 Reduction defects of unspecified limb
0.701 0.298 0.000
Q75 Other congenital malformations of skull and face bones
0.701 0.298 0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine
0.701 0.298 0.000
Q66.8 Other congenital deformities of feet
0.700 0.300 0.000
M83 Adult osteomalacia
0.700 0.300 0.000
M62.1 Other rupture of muscle (nontraumatic)
0.699 0.301 0.000
I72.1 Aneurysm of artery of upper extremity
0.699 0.301 0.000
I72.5 Aneurysm and dissection of other precerebral arteries
0.699 0.301 0.000
I72.6 Aneurysm and dissection of vertebral artery
0.699 0.301 0.000
Y59.3 Immunoglobulin
0.699 0.301 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.698 0.302 0.000
Q66.0 Talipes equinovarus
0.698 0.302 0.000
V09 Pedestrian injured in other and unspecified transport accidents
0.698 0.302 0.000
M62.80 Other specified disorders of muscle (Multiple sites)
0.697 0.303 0.000
F25.9 Schizoaffective disorder, unspecified
0.696 0.304 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.696 0.304 0.000
E70 Disorders of aromatic amino-acid metabolism
0.696 0.304 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.696 0.304 0.000
E72 Other disorders of amino-acid metabolism
0.696 0.304 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.696 0.304 0.000
E76 Disorders of glycosaminoglycan metabolism
0.696 0.304 0.000
E77 Disorders of glycoprotein metabolism
0.696 0.304 0.000
E84 Cystic fibrosis
0.696 0.304 0.000
Y52.1 Calcium-channel blockers
0.696 0.304 0.000
F21 Schizotypal disorder
0.696 0.304 0.000
F24 Induced delusional disorder
0.696 0.304 0.000
F28 Other nonorganic psychotic disorders
0.696 0.304 0.000
M85.67 Other cyst of bone (Ankle and foot)
0.694 0.306 0.000
M85.1 Skeletal fluorosis
0.693 0.306 0.000
M85.3 Osteitis condensans
0.693 0.306 0.000
M85.4 Solitary bone cyst
0.693 0.306 0.000
M85.5 Aneurysmal bone cyst
0.693 0.306 0.000
M85.9 Disorder of bone density and structure, unspecified
0.693 0.306 0.000
Y84.3 Shock therapy
0.693 0.307 0.000
Y84.5 Insertion of gastric or duodenal sound
0.693 0.307 0.000
Y84.7 Blood-sampling
0.693 0.307 0.000
I77 Other disorders of arteries and arterioles
0.693 0.307 0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.692 0.308 0.000
U52 First in a series of a regular day/night admissions
0.692 0.308 0.000
U04 Severe acute respiratory syndrome [SARS]
0.692 0.308 0.000
U06 Emergency use of U06
0.692 0.308 0.000
U07 Emergency use of U07
0.692 0.308 0.000
U50 Level of care administered to neonates
0.692 0.308 0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)
0.691 0.309 0.000
I65.1 Occlusion and stenosis of basilar artery
0.691 0.309 0.000
V24 Motorcycle rider injured in collision with heavy transport vehicle or bus
0.691 0.309 0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.690 0.310 0.000
V02 Pedestrian injured in collision with two- or three-wheeled motor vehicle
0.688 0.312 0.000
V28 Motorcycle rider injured in noncollision transport accident
0.687 0.313 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.687 0.313 0.000
F25.0 Schizoaffective disorder, manic type
0.687 0.313 0.000
M45-M49 Spondylopathies
0.686 0.314 0.000
M61 Calcification and ossification of muscle
0.686 0.314 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.686 0.314 0.000
G43 Migraine
0.685 0.315 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.685 0.315 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.685 0.315 0.000
G41.9 Status epilepticus, unspecified
0.685 0.315 0.000
R41.3 Other amnesia
0.684 0.316 0.000
V44 Car occupant injured in collision with heavy transport vehicle or bus
0.684 0.316 0.000
R45.2 Unhappiness
0.684 0.316 0.000
F25.1 Schizoaffective disorder, depressive type
0.684 0.316 0.000
W84 Unspecified threat to breathing
0.682 0.318 0.000
Y84.9 Medical procedure, unspecified
0.682 0.318 0.000
E79 Disorders of purine and pyrimidine metabolism
0.681 0.319 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.681 0.319 0.000
M87.8 Other osteonecrosis
0.680 0.319 0.000
I62.1 Nontraumatic extradural haemorrhage
0.680 0.320 0.000
F62 Enduring personality changes, not attributable to brain damage and disease
0.679 0.321 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.679 0.321 0.000
G24 Dystonia
0.677 0.323 0.000
R45.3 Demoralisation and apathy
0.676 0.324 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.676 0.324 0.000
M86.6 Other chronic osteomyelitis
0.676 0.324 0.000
Y46.2 Hydantoin derivatives
0.675 0.325 0.000
M87.0 Idiopathic aseptic necrosis of bone
0.675 0.325 0.000
M87.1 Osteonecrosis due to drugs
0.675 0.325 0.000
M87.3 Other secondary osteonecrosis
0.675 0.325 0.000
M43.06 Spondylolysis (Lumbar region)
0.675 0.325 0.000
U81.8 Agent resistant to other vancomycin-related antibiotic
0.674 0.326 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.674 0.326 0.000
I70.8 Atherosclerosis of other arteries
0.672 0.328 0.000
I70.9 Generalised and unspecified atherosclerosis
0.672 0.328 0.000
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)
0.672 0.328 0.000
M85.02 Fibrous dysplasia (monostotic) (Upper arm)
0.672 0.328 0.000
M85.03 Fibrous dysplasia (monostotic) (Forearm)
0.672 0.328 0.000
M85.04 Fibrous dysplasia (monostotic) (Hand)
0.672 0.328 0.000
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)
0.672 0.328 0.000
M85.06 Fibrous dysplasia (monostotic) (Lower leg)
0.672 0.328 0.000
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)
0.672 0.328 0.000
M85.08 Fibrous dysplasia (monostotic) (Other)
0.672 0.328 0.000
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)
0.672 0.328 0.000
M88.95 Paget's disease of bone, unspecified (Pelvic region and thigh)
0.671 0.329 0.000
Y44.5 Thrombolytic drugs
0.671 0.329 0.000
M84.3 Stress fracture, not elsewhere classified
0.670 0.330 0.000
G43.1 Migraine with aura [classical migraine]
0.670 0.330 0.000
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease
0.670 0.330 0.000
F69 Unspecified disorder of adult personality and behaviour
0.668 0.331 0.000
Y46.4 Iminostilbenes
0.668 0.332 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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