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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs11678166
log Bayes Factor = 11.2921
Chromosome 2   position 61,157,720  (GRCh37) Explore rs11678166 on Ensembl!
Variant rs11678166 is part of Cluster X0060

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
J30-J39 Other diseases of upper respiratory tract
1.000 0.000 0.000
J34 Other disorders of nose and nasal sinuses
1.000 0.000 0.000
M20-M25 Other joint disorders
0.999 0.001 0.000
Chapter X Diseases of the respiratory system
0.999 0.001 0.000
I20 Angina pectoris
0.999 0.001 0.000
I25.1 Atherosclerotic heart disease
0.995 0.005 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.993 0.007 0.000
I21 Acute myocardial infarction
0.990 0.010 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.989 0.011 0.000
M25 Other joint disorders, not elsewhere classified
0.986 0.014 0.000
J34.2 Deviated nasal septum
0.986 0.014 0.000
J34.3 Hypertrophy of nasal turbinates
0.983 0.017 0.000
I30-I52 Other forms of heart disease
0.982 0.018 0.000
H25-H28 Disorders of lens
0.979 0.021 0.000
I20.0 Unstable angina
0.976 0.024 0.000
M25.5 Pain in joint
0.972 0.028 0.000
H25 Senile cataract
0.972 0.028 0.000
M50-M54 Other dorsopathies
0.968 0.032 0.000
I20.9 Angina pectoris, unspecified
0.964 0.036 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.953 0.047 0.000
M25.56 Pain in joint (Lower leg)
0.950 0.050 0.000
I44 Atrioventricular and left bundle-branch block
0.949 0.051 0.000
H25.8 Other senile cataract
0.936 0.064 0.000
I35 Nonrheumatic aortic valve disorders
0.936 0.064 0.000
M50 Cervical disk disorders
0.928 0.072 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.926 0.074 0.000
J32 Chronic sinusitis
0.926 0.074 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.924 0.076 0.000
H30-H36 Disorders of choroid and retina
0.923 0.077 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.921 0.079 0.000
M20 Acquired deformities of fingers and toes
0.916 0.084 0.000
M20.4 Other hammer toe(s) (acquired)
0.906 0.094 0.000
J36 Peritonsillar abscess
0.904 0.096 0.000
I20.8 Other forms of angina pectoris
0.903 0.097 0.000
S50-S59 Injuries to the elbow and forearm
0.895 0.105 0.000
H04 Disorders of lachrymal system
0.890 0.110 0.000
M35 Other systemic involvement of connective tissue
0.884 0.116 0.000
H33 Retinal detachments and breaks
0.875 0.125 0.000
I44.1 Atrioventricular block, second degree
0.870 0.130 0.000
H04.2 Epiphora
0.870 0.130 0.000
Chapter I Certain infectious and parasitic diseases
0.867 0.133 0.000
M50.1 Cervical disk disorder with radiculopathy
0.864 0.136 0.000
I05-I09 Chronic rheumatic heart diseases
0.859 0.141 0.000
I25.2 Old myocardial infarction
0.858 0.142 0.000
H55-H59 Other disorders of eye and adnexa
0.852 0.148 0.000
M25.51 Pain in joint (Shoulder region)
0.852 0.148 0.000
H25.0 Senile incipient cataract
0.849 0.151 0.000
J34.1 Cyst and mucocele of nose and nasal sinus
0.846 0.154 0.000
I25.5 Ischaemic cardiomyopathy
0.844 0.156 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.843 0.157 0.000
I31 Other diseases of pericardium
0.843 0.157 0.000
I45 Other conduction disorders
0.838 0.162 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.837 0.163 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.837 0.163 0.000
H25.9 Senile cataract, unspecified
0.834 0.166 0.000
H53-H54 Visual disturbances and blindness
0.829 0.171 0.000
J33 Nasal polyp
0.828 0.172 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.828 0.172 0.000
M31 Other necrotising vasculopathies
0.827 0.173 0.000
I35.0 Aortic (valve) stenosis
0.827 0.173 0.000
I60-I69 Cerebrovascular diseases
0.824 0.176 0.000
I44.0 Atrioventricular block, first degree
0.822 0.178 0.000
M25.9 Joint disorder, unspecified
0.820 0.180 0.000
I49 Other cardiac arrhythmias
0.820 0.180 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.816 0.184 0.000
J09-J18 Influenza and pneumonia
0.816 0.184 0.000
S50 Superficial injury of forearm
0.808 0.192 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.807 0.193 0.000
M25.54 Pain in joint (Hand)
0.802 0.198 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.802 0.198 0.000
M40-M43 Deforming dorsopathies
0.801 0.199 0.000
M80-M85 Disorders of bone density and structure
0.797 0.203 0.000
M25.59 Pain in joint (Site unspecified)
0.791 0.209 0.000
H05 Disorders of orbit
0.787 0.213 0.000
M54 Dorsalgia
0.787 0.213 0.000
M50.0 Cervical disk disorder with myelopathy
0.787 0.213 0.000
I35.8 Other aortic valve disorders
0.786 0.214 0.000
M20.1 Hallux valgus (acquired)
0.785 0.215 0.000
M25.4 Effusion of joint
0.785 0.215 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.785 0.215 0.000
M22 Disorders of patella
0.783 0.217 0.000
J32.2 Chronic ethmoidal sinusitis
0.782 0.218 0.000
H43-H45 Disorders of vitreous body and globe
0.782 0.218 0.000
H25.1 Senile nuclear cataract
0.780 0.220 0.000
I38 Endocarditis, valve unspecified
0.779 0.221 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.779 0.221 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.776 0.224 0.000
J33.0 Polyp of nasal cavity
0.776 0.224 0.000
S10-S19 Injuries to the neck
0.775 0.225 0.000
J32.9 Chronic sinusitis, unspecified
0.772 0.228 0.000
I31.3 Pericardial effusion (noninflammatory)
0.771 0.229 0.000
Chapter VIII Diseases of the ear and mastoid process
0.771 0.229 0.000
M65-M68 Disorders of synovium and tendon
0.770 0.230 0.000
H10-H13 Disorders of conjunctiva
0.768 0.232 0.000
M34 Systemic sclerosis
0.767 0.233 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.767 0.233 0.000
M05-M14 Inflammatory polyarthropathies
0.766 0.234 0.000
A30-A49 Other bacterial diseases
0.765 0.235 0.000
I08 Multiple valve diseases
0.763 0.237 0.000
I44.7 Left bundle-branch block, unspecified
0.762 0.238 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.751 0.249 0.000
J32.8 Other chronic sinusitis
0.751 0.249 0.000
H27 Other disorders of lens
0.749 0.251 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.745 0.255 0.000
M50.2 Other cervical disk displacement
0.745 0.255 0.000
M00-M03 Infectious arthropathies
0.744 0.256 0.000
M35.0 Sicca syndrome [Sjogren]
0.742 0.257 0.000
I35.1 Aortic (valve) insufficiency
0.742 0.258 0.000
I42 Cardiomyopathy
0.741 0.258 0.000
H57 Other disorders of eye and adnexa
0.741 0.259 0.000
M23 Internal derangement of knee
0.739 0.261 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.736 0.264 0.000
S52 Fracture of forearm
0.736 0.264 0.000
J30 Vasomotor and allergic rhinitis
0.735 0.265 0.000
I20.1 Angina pectoris with documented spasm
0.734 0.266 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.733 0.266 0.000
M60-M63 Disorders of muscles
0.733 0.267 0.000
H33.4 Traction detachment of retina
0.733 0.267 0.000
M25.0 Haemarthrosis
0.731 0.269 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.730 0.270 0.000
I24 Other acute ischaemic heart diseases
0.730 0.270 0.000
M21 Other acquired deformities of limbs
0.730 0.270 0.000
M51 Other intervertebral disk disorders
0.728 0.272 0.000
S90-S99 Injuries to the ankle and foot
0.728 0.272 0.000
J86 Pyothorax
0.721 0.279 0.000
H33.0 Retinal detachment with retinal break
0.721 0.279 0.000
H35 Other retinal disorders
0.721 0.279 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.720 0.280 0.000
H33.1 Retinoschisis and retinal cysts
0.720 0.280 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.3 Aneurysm of heart
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
J37 Chronic laryngitis and laryngotracheitis
0.717 0.283 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.717 0.283 0.000
M25.53 Pain in joint (Forearm)
0.716 0.284 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.716 0.284 0.000
M33 Dermatopolymyositis
0.716 0.284 0.000
M32 Systemic lupus erythematosus
0.716 0.284 0.000
M30 Polyarteritis nodosa and related conditions
0.716 0.284 0.000
I45.8 Other specified conduction disorders
0.715 0.285 0.000
H20 Iridocyclitis
0.712 0.288 0.000
H01 Other inflammation of eyelid
0.711 0.289 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.710 0.290 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.710 0.290 0.000
H54 Blindness and low vision
0.710 0.290 0.000
S70-S79 Injuries to the hip and thigh
0.710 0.290 0.000
H33.3 Retinal breaks without detachment
0.709 0.291 0.000
H04.4 Chronic inflammation of lachrymal passages
0.709 0.291 0.000
M91-M94 Chondropathies
0.708 0.292 0.000
I44.2 Atrioventricular block, complete
0.707 0.292 0.000
M25.3 Other instability of joint
0.707 0.293 0.000
M25.2 Flail joint
0.707 0.293 0.000
M25.1 Fistula of joint
0.707 0.293 0.000
S50.9 Superficial injury of forearm, unspecified
0.707 0.293 0.000
M35.7 Hypermobility syndrome
0.706 0.293 0.000
I30 Acute pericarditis
0.704 0.296 0.000
S40-S49 Injuries to the shoulder and upper arm
0.704 0.296 0.000
I52 Other heart disorders in diseases classified elsewhere
0.704 0.296 0.000
I48 Atrial fibrillation and flutter
0.704 0.296 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.704 0.296 0.000
I41 Myocarditis in diseases classified elsewhere
0.704 0.296 0.000
I40 Acute myocarditis
0.704 0.296 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.704 0.296 0.000
I37 Pulmonary valve disorders
0.704 0.296 0.000
I36 Nonrheumatic tricuspid valve disorders
0.704 0.296 0.000
I32 Pericarditis in diseases classified elsewhere
0.704 0.296 0.000
M31.6 Other giant cell arteritis
0.704 0.296 0.000
M25.52 Pain in joint (Upper arm)
0.703 0.297 0.000
Chapter XXII Codes for special purposes
0.703 0.297 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.702 0.298 0.000
J31.0 Chronic rhinitis
0.702 0.298 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.701 0.299 0.000
M25.96 Joint disorder, unspecified (Lower leg)
0.700 0.299 0.000
L40-L45 Papulosquamous disorders
0.700 0.300 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.698 0.302 0.000
M25.58 Pain in joint (Other)
0.697 0.303 0.000
I35.9 Aortic valve disorder, unspecified
0.697 0.303 0.000
S56 Injury of muscle and tendon at forearm level
0.697 0.303 0.000
H25.2 Senile cataract, morgagnian type
0.697 0.303 0.000
M20.3 Other deformity of hallux (acquired)
0.694 0.306 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.693 0.307 0.000
M53 Other dorsopathies, not elsewhere classified
0.693 0.307 0.000
J60-J70 Lung diseases due to external agents
0.692 0.308 0.000
M84 Disorders of continuity of bone
0.692 0.308 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.692 0.308 0.000
I63 Cerebral infarction
0.688 0.312 0.000
M86-M90 Other osteopathies
0.686 0.314 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.684 0.316 0.000
I33 Acute and subacute endocarditis
0.684 0.316 0.000
T33-T35 Frostbite
0.683 0.317 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.683 0.317 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.683 0.317 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.683 0.317 0.000
T00-T07 Injuries involving multiple body regions
0.683 0.317 0.000
I44.6 Other and unspecified fascicular block
0.681 0.319 0.000
I44.5 Left posterior fascicular block
0.681 0.319 0.000
I44.4 Left anterior fascicular block
0.681 0.319 0.000
I44.3 Other and unspecified atrioventricular block
0.681 0.319 0.000
M35.3 Polymyalgia rheumatica
0.680 0.320 0.000
J32.0 Chronic maxillary sinusitis
0.678 0.321 0.000
T39.0 Salicylates
0.678 0.322 0.000
I45.9 Conduction disorder, unspecified
0.675 0.325 0.000
I49.4 Other and unspecified premature depolarisation
0.675 0.325 0.000
M43 Other deforming dorsopathies
0.672 0.328 0.000
A41 Other septicaemia
0.671 0.329 0.000
M24 Other specific joint derangements
0.671 0.329 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.671 0.329 0.000
L40 Psoriasis
0.670 0.330 0.000
T18 Foreign body in alimentary tract
0.670 0.330 0.000
I05 Rheumatic mitral valve diseases
0.669 0.331 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.668 0.332 0.000
S50.8 Other superficial injuries of forearm
0.667 0.333 0.000
M50.9 Cervical disk disorder, unspecified
0.665 0.334 0.000
M50.8 Other cervical disk disorders
0.665 0.334 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.664 0.336 0.000
T79-T79 Certain early complications of trauma
0.664 0.336 0.000
J32.4 Chronic pansinusitis
0.664 0.336 0.000
J32.3 Chronic sphenoidal sinusitis
0.664 0.336 0.000
J32.1 Chronic frontal sinusitis
0.664 0.336 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.662 0.338 0.000
H31 Other disorders of choroid
0.662 0.338 0.000
H30 Chorioretinal inflammation
0.662 0.338 0.000
S20-S29 Injuries to the thorax
0.661 0.339 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.660 0.340 0.000
J81 Pulmonary oedema
0.659 0.341 0.000
I21.9 Acute myocardial infarction, unspecified
0.657 0.343 0.000
J80 Adult respiratory distress syndrome
0.656 0.344 0.000
H90-H95 Other disorders of ear
0.656 0.344 0.000
M23.8 Other internal derangements of knee
0.655 0.345 0.000
B35-B49 Mycoses
0.653 0.347 0.000
I08.0 Disorders of both mitral and aortic valves
0.653 0.347 0.000
H05.8 Other disorders of orbit
0.652 0.347 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.650 0.350 0.000
I46 Cardiac arrest
0.649 0.351 0.000
M25.50 Pain in joint (Multiple sites)
0.648 0.352 0.000
H04.1 Other disorders of lachrymal gland
0.648 0.352 0.000
T39.1 4-Aminophenol derivatives
0.646 0.354 0.000
S51 Open wound of forearm
0.645 0.355 0.000
L40.9 Psoriasis, unspecified
0.645 0.355 0.000
I45.3 Trifascicular block
0.645 0.355 0.000
I49.5 Sick sinus syndrome
0.645 0.355 0.000
B25-B34 Other viral diseases
0.644 0.356 0.000
H33.2 Serous retinal detachment
0.643 0.357 0.000
S59 Other and unspecified injuries of forearm
0.641 0.358 0.000
S58 Traumatic amputation of forearm
0.641 0.358 0.000
S57 Crushing injury of forearm
0.641 0.358 0.000
S55 Injury of blood vessels at forearm level
0.641 0.358 0.000
S54 Injury of nerves at forearm level
0.641 0.358 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.641 0.358 0.000
B65-B83 Helminthiases
0.641 0.359 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.639 0.360 0.000
M25.46 Effusion of joint (Lower leg)
0.639 0.361 0.000
I62 Other nontraumatic intracranial haemorrhage
0.638 0.361 0.000
J86.9 Pyothorax without fistula
0.638 0.362 0.000
H04.9 Disorder of lachrymal system, unspecified
0.638 0.362 0.000
H04.8 Other disorders of lachrymal system
0.638 0.362 0.000
H04.6 Other changes in lachrymal passages
0.638 0.362 0.000
H04.3 Acute and unspecified inflammation of lachrymal passages
0.638 0.362 0.000
H04.0 Dacryoadenitis
0.638 0.362 0.000
I49.1 Atrial premature depolarisation
0.638 0.362 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.637 0.363 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.636 0.364 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.636 0.364 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.634 0.366 0.000
M35.8 Other specified systemic involvement of connective tissue
0.634 0.366 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.634 0.366 0.000
M35.5 Multifocal fibrosclerosis
0.634 0.366 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.634 0.366 0.000
M35.2 Behcet's disease
0.634 0.366 0.000
M35.1 Other overlap syndromes
0.634 0.366 0.000
S19 Other and unspecified injuries of neck
0.633 0.367 0.000
B15-B19 Viral hepatitis
0.633 0.367 0.000
I27 Other pulmonary heart diseases
0.633 0.367 0.000
J31.2 Chronic pharyngitis
0.632 0.368 0.000
M22.8 Other disorders of patella
0.632 0.368 0.000
M25.8 Other specified joint disorders
0.629 0.370 0.000
H33.5 Other retinal detachments
0.628 0.371 0.000
I24.8 Other forms of acute ischaemic heart disease
0.628 0.372 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.627 0.373 0.000
M54.9 Dorsalgia, unspecified
0.625 0.375 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.625 0.375 0.000
H05.2 Exophthalmic conditions
0.624 0.376 0.000
I49.3 Ventricular premature depolarisation
0.624 0.376 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.623 0.377 0.000
I49.0 Ventricular fibrillation and flutter
0.623 0.377 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.623 0.377 0.000
M65 Synovitis and tenosynovitis
0.622 0.377 0.000
B99-B99 Other infectious diseases
0.622 0.378 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.622 0.378 0.000
B50-B64 Protozoal diseases
0.622 0.378 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.622 0.378 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.622 0.378 0.000
A75-A79 Rickettsioses
0.622 0.378 0.000
A70-A74 Other diseases caused by chlamydiae
0.622 0.378 0.000
A65-A69 Other spirochaetal diseases
0.622 0.378 0.000
A20-A28 Certain zoonotic bacterial diseases
0.622 0.378 0.000
A15-A19 Tuberculosis
0.622 0.378 0.000
H46 Optic neuritis
0.621 0.378 0.000
M45-M49 Spondylopathies
0.621 0.379 0.000
M54.3 Sciatica
0.621 0.379 0.000
M50.3 Other cervical disk degeneration
0.619 0.380 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.619 0.381 0.000
H91 Other hearing loss
0.618 0.382 0.000
I61 Intracerebral haemorrhage
0.617 0.382 0.000
H34 Retinal vascular occlusions
0.617 0.383 0.000
I09 Other rheumatic heart diseases
0.616 0.384 0.000
I06 Rheumatic aortic valve diseases
0.616 0.384 0.000
I60 Subarachnoid haemorrhage
0.615 0.385 0.000
I42.2 Other hypertrophic cardiomyopathy
0.615 0.385 0.000
S00-S09 Injuries to the head
0.615 0.385 0.000
H35.6 Retinal haemorrhage
0.613 0.387 0.000
J18 Pneumonia, organism unspecified
0.613 0.387 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.613 0.387 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.611 0.388 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.611 0.389 0.000
T66-T78 Other and unspecified effects of external causes
0.610 0.389 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.609 0.391 0.000
H57.0 Anomalies of pupillary function
0.608 0.392 0.000
I65.2 Occlusion and stenosis of carotid artery
0.608 0.392 0.000
J10 Influenza due to identified influenza virus
0.606 0.394 0.000
H43 Disorders of vitreous body
0.605 0.395 0.000
S52.0 Fracture of upper end of ulna
0.605 0.395 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.604 0.395 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.604 0.395 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.604 0.395 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.604 0.395 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.604 0.395 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.604 0.395 0.000
T36 Poisoning by systemic antibiotics
0.604 0.395 0.000
I31.8 Other specified diseases of pericardium
0.604 0.396 0.000
I31.2 Haemopericardium, not elsewhere classified
0.604 0.396 0.000
I31.1 Chronic constrictive pericarditis
0.604 0.396 0.000
I31.0 Chronic adhesive pericarditis
0.604 0.396 0.000
J39 Other diseases of upper respiratory tract
0.603 0.397 0.000
M25.57 Pain in joint (Ankle and foot)
0.602 0.398 0.000
I45.4 Nonspecific intraventricular block
0.601 0.399 0.000
I45.2 Bifascicular block
0.601 0.399 0.000
I45.0 Right fascicular block
0.601 0.399 0.000
M34.1 CR(E)ST syndrome
0.601 0.399 0.000
A80-A89 Viral infections of the central nervous system
0.600 0.399 0.000
J85 Abscess of lung and mediastinum
0.600 0.400 0.000
H40-H42 Glaucoma
0.600 0.400 0.000
J31.1 Chronic nasopharyngitis
0.600 0.400 0.000
M23.9 Internal derangement of knee, unspecified
0.600 0.400 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.600 0.400 0.000
S80-S89 Injuries to the knee and lower leg
0.600 0.400 0.000
M54.5 Low back pain
0.600 0.400 0.000
I49.8 Other specified cardiac arrhythmias
0.599 0.401 0.000
T40.2 Other opioids
0.599 0.401 0.000
H20.0 Acute and subacute iridocyclitis
0.599 0.401 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.598 0.402 0.000
A41.9 Septicaemia, unspecified
0.596 0.404 0.000
Q60-Q64 Congenital malformations of the urinary system
0.595 0.405 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.595 0.405 0.000
A49 Bacterial infection of unspecified site
0.594 0.406 0.000
H16 Keratitis
0.594 0.406 0.000
T18.1 Foreign body in oesophagus
0.594 0.406 0.000
S90 Superficial injury of ankle and foot
0.594 0.406 0.000
J33.1 Polypoid sinus degeneration
0.594 0.406 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.593 0.406 0.000
H21 Other disorders of iris and ciliary body
0.593 0.406 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.593 0.406 0.000
H17 Corneal scars and opacities
0.593 0.406 0.000
H15 Disorders of sclera
0.593 0.406 0.000
S52.6 Fracture of lower end of both ulna and radius
0.593 0.407 0.000
M31.9 Necrotising vasculopathy, unspecified
0.593 0.407 0.000
M31.8 Other specified necrotising vasculopathies
0.593 0.407 0.000
M31.7 Microscopic polyangiitis
0.593 0.407 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.593 0.407 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.593 0.407 0.000
M31.3 Wegener's granulomatosis
0.593 0.407 0.000
M31.2 Lethal midline granuloma
0.593 0.407 0.000
M31.1 Thrombotic microangiopathy
0.593 0.407 0.000
M31.0 Hypersensitivity angiitis
0.593 0.407 0.000
H55 Nystagmus and other irregular eye movements
0.593 0.407 0.000
B07 Viral warts
0.593 0.407 0.000
H36 Retinal disorders in diseases classified elsewhere
0.593 0.407 0.000
H27.8 Other specified disorders of lens
0.591 0.409 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.591 0.409 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.591 0.409 0.000
M25.7 Osteophyte
0.591 0.409 0.000
H91.9 Hearing loss, unspecified
0.590 0.410 0.000
Q50-Q56 Congenital malformations of genital organs
0.589 0.410 0.000
H10 Conjunctivitis
0.589 0.411 0.000
H53 Visual disturbances
0.589 0.411 0.000
J30.1 Allergic rhinitis due to pollen
0.589 0.411 0.000
M25.99 Joint disorder, unspecified (Site unspecified)
0.588 0.412 0.000
M25.98 Joint disorder, unspecified (Other)
0.588 0.412 0.000
M25.97 Joint disorder, unspecified (Ankle and foot)
0.588 0.412 0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)
0.588 0.412 0.000
M25.94 Joint disorder, unspecified (Hand)
0.588 0.412 0.000
M25.93 Joint disorder, unspecified (Forearm)
0.588 0.412 0.000
M25.92 Joint disorder, unspecified (Upper arm)
0.588 0.412 0.000
M25.91 Joint disorder, unspecified (Shoulder region)
0.588 0.412 0.000
M25.90 Joint disorder, unspecified (Multiple sites)
0.588 0.412 0.000
I49.2 Junctional premature depolarisation
0.588 0.412 0.000
M85 Other disorders of bone density and structure
0.587 0.413 0.000
I67 Other cerebrovascular diseases
0.587 0.413 0.000
H54.4 Blindness, one eye
0.586 0.414 0.000
H44 Disorders of globe
0.585 0.414 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.585 0.415 0.000
Q80-Q89 Other congenital malformations
0.585 0.415 0.000
Q35-Q37 Cleft lip and cleft palate
0.585 0.415 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.585 0.415 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.585 0.415 0.000
Q00-Q07 Congenital malformations of the nervous system
0.585 0.415 0.000
J17 Pneumonia in diseases classified elsewhere
0.585 0.415 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.585 0.415 0.000
J12 Viral pneumonia, not elsewhere classified
0.585 0.415 0.000
J14 Pneumonia due to Haemophilus influenzae
0.585 0.415 0.000
J09 Influenza due to certain identified influenza virus
0.585 0.415 0.000
I45.5 Other specified heart block
0.584 0.416 0.000
M05 Seropositive rheumatoid arthritis
0.584 0.416 0.000
S52.7 Multiple fractures of forearm
0.584 0.416 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.583 0.417 0.000
H57.9 Disorder of eye and adnexa, unspecified
0.583 0.417 0.000
I22 Subsequent myocardial infarction
0.582 0.418 0.000
M43.1 Spondylolisthesis
0.580 0.420 0.000
M22.2 Patellofemoral disorders
0.580 0.420 0.000
M13 Other arthritis
0.580 0.420 0.000
S50.7 Multiple superficial injuries of forearm
0.579 0.421 0.000
S50.1 Contusion of other and unspecified parts of forearm
0.579 0.421 0.000
S50.0 Contusion of elbow
0.579 0.421 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.579 0.421 0.000
S37 Injury of urinary and pelvic organs
0.579 0.421 0.000
S36 Injury of intra-abdominal organs
0.579 0.421 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.579 0.421 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.579 0.421 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.579 0.421 0.000
S31 Open wound of abdomen, lower back and pelvis
0.579 0.421 0.000
M80 Osteoporosis with pathological fracture
0.579 0.421 0.000
T92 Sequelae of injuries of upper limb
0.578 0.422 0.000
H18 Other disorders of cornea
0.578 0.422 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.578 0.422 0.000
J20-J22 Other acute lower respiratory infections
0.578 0.422 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.577 0.423 0.000
M21.4 Flat foot [pes planus] (acquired)
0.576 0.424 0.000
M07 Psoriatic and enteropathic arthropathies
0.576 0.424 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.576 0.424 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.575 0.425 0.000
M42 Spinal osteochondrosis
0.574 0.426 0.000
M40 Kyphosis and lordosis
0.574 0.426 0.000
H35.9 Retinal disorder, unspecified
0.574 0.426 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.574 0.426 0.000
I45.1 Other and unspecified right bundle-branch block
0.574 0.426 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.574 0.426 0.000
A41.8 Other specified septicaemia
0.573 0.427 0.000
S32 Fracture of lumbar spine and pelvis
0.573 0.427 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.572 0.428 0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)
0.572 0.428 0.000
M83 Adult osteomalacia
0.571 0.428 0.000
M82 Osteoporosis in diseases classified elsewhere
0.571 0.428 0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.569 0.431 0.000
H65-H75 Diseases of middle ear and mastoid
0.567 0.433 0.000
M23.4 Loose body in knee
0.567 0.433 0.000
M84.8 Other disorders of continuity of bone
0.567 0.433 0.000
H11 Other disorders of conjunctiva
0.566 0.434 0.000
T90 Sequelae of injuries of head
0.565 0.435 0.000
H05.9 Disorder of orbit, unspecified
0.565 0.435 0.000
H05.5 Retained (old) foreign body following penetrating wound of orbit
0.565 0.435 0.000
H05.4 Enophthalmos
0.565 0.435 0.000
H05.3 Deformity of orbit
0.565 0.435 0.000
H05.1 Chronic inflammatory disorders of orbit
0.565 0.435 0.000
H05.0 Acute inflammation of orbit
0.565 0.435 0.000
M25.47 Effusion of joint (Ankle and foot)
0.564 0.435 0.000
H35.2 Other proliferative retinopathy
0.564 0.436 0.000
M54.8 Other dorsalgia
0.564 0.436 0.000
M54.6 Pain in thoracic spine
0.564 0.436 0.000
M54.0 Panniculitis affecting regions of neck and back
0.564 0.436 0.000
L50-L54 Urticaria and erythema
0.564 0.436 0.000
M25.49 Effusion of joint (Site unspecified)
0.563 0.437 0.000
M25.48 Effusion of joint (Other)
0.563 0.437 0.000
M25.45 Effusion of joint (Pelvic region and thigh)
0.563 0.437 0.000
M25.44 Effusion of joint (Hand)
0.563 0.437 0.000
M25.43 Effusion of joint (Forearm)
0.563 0.437 0.000
M25.42 Effusion of joint (Upper arm)
0.563 0.437 0.000
M25.41 Effusion of joint (Shoulder region)
0.563 0.437 0.000
M25.40 Effusion of joint (Multiple sites)
0.563 0.437 0.000
S41 Open wound of shoulder and upper arm
0.562 0.438 0.000
M22.1 Recurrent subluxation of patella
0.561 0.439 0.000
M22.9 Disorder of patella, unspecified
0.561 0.439 0.000
M22.3 Other derangements of patella
0.561 0.439 0.000
M22.0 Recurrent dislocation of patella
0.561 0.439 0.000
M00 Pyogenic arthritis
0.561 0.439 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.560 0.439 0.000
J11 Influenza, virus not identified
0.560 0.440 0.000
H35.5 Hereditary retinal dystrophy
0.560 0.440 0.000
M11 Other crystal arthropathies
0.559 0.440 0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.559 0.441 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.559 0.441 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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