TreeWAS – Variant ID: rs1065853

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E78.0 Pure hypercholesterolaemia	0.000	0.000	1.000
I20.9 Angina pectoris, unspecified	0.000	0.000	1.000
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.000	1.000
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.000	1.000
I25.1 Atherosclerotic heart disease	0.000	0.000	1.000
Z95.1 Presence of aortocoronary bypass graft	0.000	0.000	1.000
I25 Chronic ischaemic heart disease	0.000	0.000	1.000
I21 Acute myocardial infarction	0.000	0.000	1.000
I20 Angina pectoris	0.000	0.000	1.000
I20-I25 Ischaemic heart diseases	0.000	0.000	1.000
E78.5 Hyperlipidaemia, unspecified	0.000	0.000	1.000
I25.2 Old myocardial infarction	0.000	0.000	1.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.000	1.000
I21.4 Acute subendocardial myocardial infarction	0.000	0.002	0.998
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.005	0.995
I20.0 Unstable angina	0.000	0.005	0.995
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.006	0.994
Z95 Presence of cardiac and vascular implants and grafts	0.000	0.010	0.990
I21.9 Acute myocardial infarction, unspecified	0.000	0.010	0.990
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.028	0.972
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.034	0.966
I20.8 Other forms of angina pectoris	0.000	0.080	0.920
I25.5 Ischaemic cardiomyopathy	0.000	0.103	0.897
I24 Other acute ischaemic heart diseases	0.000	0.113	0.887
M81.99 Osteoporosis, unspecified (Site unspecified)	0.878	0.122	0.000
M81.9 Osteoporosis, unspecified	0.870	0.130	0.000
M81 Osteoporosis without pathological fracture	0.860	0.140	0.000
M80-M85 Disorders of bone density and structure	0.854	0.146	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.852	0.148	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.149	0.851
M20-M25 Other joint disorders	0.849	0.151	0.000
I22 Subsequent myocardial infarction	0.000	0.160	0.840
I25.3 Aneurysm of heart	0.000	0.179	0.821
M70-M79 Other soft tissue disorders	0.818	0.182	0.000
M21 Other acquired deformities of limbs	0.818	0.182	0.000
M40-M43 Deforming dorsopathies	0.809	0.191	0.000
M24 Other specific joint derangements	0.802	0.198	0.000
M45-M49 Spondylopathies	0.779	0.221	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.000	0.226	0.774
M20 Acquired deformities of fingers and toes	0.770	0.230	0.000
M43 Other deforming dorsopathies	0.770	0.230	0.000
M34 Systemic sclerosis	0.765	0.235	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.239	0.761
M70 Soft tissue disorders related to use, overuse and pressure	0.755	0.245	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.249	0.751
M86-M90 Other osteopathies	0.744	0.256	0.000
M24.0 Loose body in joint	0.743	0.257	0.000
M81.98 Osteoporosis, unspecified (Other)	0.735	0.265	0.000
M79 Other soft tissue disorders, not elsewhere classified	0.727	0.273	0.000
E78.2 Mixed hyperlipidaemia	0.000	0.273	0.727
M43.1 Spondylolisthesis	0.725	0.275	0.000
M47 Spondylosis	0.720	0.280	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.283	0.717
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.283	0.717
I25.6 Silent myocardial ischaemia	0.000	0.283	0.717
I23 Certain current complications following acute myocardial infarction	0.000	0.283	0.717
M77 Other enthesopathies	0.717	0.283	0.000
E78.6 Lipoprotein deficiency	0.000	0.283	0.717
E78.3 Hyperchylomicronaemia	0.000	0.283	0.717
I25.4 Coronary artery aneurysm	0.000	0.284	0.716
M70.6 Trochanteric bursitis	0.711	0.289	0.000
M25 Other joint disorders, not elsewhere classified	0.700	0.300	0.000
M24.07 Loose body in joint (Ankle and foot)	0.697	0.303	0.000
M43.17 Spondylolisthesis (Lumbosacral region)	0.697	0.303	0.000
M72 Fibroblastic disorders	0.695	0.305	0.000
M21.3 Wrist or foot drop (acquired)	0.694	0.306	0.000
I20.1 Angina pectoris with documented spasm	0.000	0.307	0.693
M21.0 Valgus deformity, not elsewhere classified	0.689	0.311	0.000
M47.2 Other spondylosis with radiculopathy	0.684	0.316	0.000
M89 Other disorders of bone	0.683	0.317	0.000
M70.65 Trochanteric bursitis-Pelvic/Thigh	0.680	0.320	0.000
M48 Other spondylopathies	0.680	0.320	0.000
M40 Kyphosis and lordosis	0.677	0.323	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.673	0.327	0.000
M21.9 Acquired deformity of limb, unspecified	0.671	0.329	0.000
E78.1 Pure hyperglyceridaemia	0.000	0.330	0.670
M20.3 Other deformity of hallux (acquired)	0.669	0.331	0.000
M85 Other disorders of bone density and structure	0.668	0.332	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.667	0.333	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.664	0.336	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.660	0.340	0.000
M21.2 Flexion deformity	0.659	0.341	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.657	0.343	0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.653	0.347	0.000
M82 Osteoporosis in diseases classified elsewhere	0.643	0.357	0.000
M24.2 Disorder of ligament	0.642	0.358	0.000
E78.8 Other disorders of lipoprotein metabolism	0.000	0.360	0.639
M00-M03 Infectious arthropathies	0.637	0.363	0.000
I24.1 Dressler's syndrome	0.000	0.364	0.636
E78.4 Other hyperlipidaemia	0.000	0.365	0.635
M34.9 Systemic sclerosis, unspecified	0.633	0.367	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.631	0.369	0.000
M72.2 Plantar fascial fibromatosis	0.630	0.370	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.629	0.371	0.000
M47.8 Other spondylosis	0.629	0.371	0.000
M34.1 CR(E)ST syndrome	0.628	0.372	0.000
M81.4 Drug-induced osteoporosis	0.624	0.376	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.624	0.376	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.624	0.376	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.624	0.376	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.624	0.376	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.624	0.376	0.000
M77.0 Medial epicondylitis	0.621	0.379	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.618	0.382	0.000
M81.8 Other osteoporosis	0.617	0.383	0.000
M81.6 Localised osteoporosis [Lequesne]	0.617	0.383	0.000
M81.5 Idiopathic osteoporosis	0.617	0.383	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.617	0.383	0.000
M81.1 Postoophorectomy osteoporosis	0.617	0.383	0.000
M81.0 Postmenopausal osteoporosis	0.617	0.383	0.000
Z95.3 Presence of xenogenic heart valve	0.000	0.384	0.616
K81 Cholecystitis	0.616	0.384	0.000
I22.8 Subsequent myocardial infarction of other sites	0.000	0.385	0.615
K81.0 Acute cholecystitis	0.615	0.385	0.000
M79.8 Other specified soft tissue disorders	0.615	0.385	0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.614	0.386	0.000
Z95.0 Presence of cardiac pacemaker	0.000	0.386	0.614
M43.2 Other fusion of spine	0.613	0.387	0.000
M83 Adult osteomalacia	0.612	0.388	0.000
M79.0 Rheumatism, unspecified	0.611	0.389	0.000
M34.8 Other forms of systemic sclerosis	0.611	0.389	0.000
M89.8 Other specified disorders of bone	0.610	0.390	0.000
M21.4 Flat foot [pes planus] (acquired)	0.609	0.391	0.000
M32 Systemic lupus erythematosus	0.609	0.391	0.000
M20.5 Other deformities of toe(s) (acquired)	0.609	0.391	0.000
M33 Dermatopolymyositis	0.609	0.391	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.608	0.392	0.000
M91-M94 Chondropathies	0.607	0.393	0.000
M30 Polyarteritis nodosa and related conditions	0.607	0.393	0.000
K83 Other diseases of biliary tract	0.607	0.393	0.000
M20.1 Hallux valgus (acquired)	0.606	0.394	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.605	0.395	0.000
M79.5 Residual foreign body in soft tissue	0.603	0.397	0.000
M81.2 Osteoporosis of disuse	0.601	0.399	0.000
M60-M63 Disorders of muscles	0.600	0.400	0.000
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.598	0.402	0.000
M21.6 Other acquired deformities of ankle and foot	0.593	0.407	0.000
M73 Soft tissue disorders in diseases classified elsewhere	0.587	0.413	0.000
M21.8 Other specified acquired deformities of limbs	0.587	0.413	0.000
M21.7 Unequal limb length (acquired)	0.587	0.413	0.000
M77.4 Metatarsalgia	0.586	0.414	0.000
K83.1 Obstruction of bile duct	0.586	0.414	0.000
M86 Osteomyelitis	0.586	0.414	0.000
M43.0 Spondylolysis	0.584	0.416	0.000
M72.27 Plantar fascial fibromatosis-Ankle/Foot	0.584	0.416	0.000
M89.0 Algoneurodystrophy	0.583	0.417	0.000
M40.2 Other and unspecified kyphosis	0.583	0.417	0.000
K80 Cholelithiasis	0.583	0.417	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.582	0.418	0.000
M22 Disorders of patella	0.582	0.418	0.000
M20.0 Deformity of finger(s)	0.582	0.418	0.000
M42 Spinal osteochondrosis	0.580	0.420	0.000
M84 Disorders of continuity of bone	0.579	0.420	0.000
M85.8 Other specified disorders of bone density and structure	0.577	0.423	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.425	0.575
M48.5 Collapsed vertebra, not elsewhere classified	0.575	0.425	0.000
M24.9 Joint derangement, unspecified	0.575	0.425	0.000
M24.7 Protrusio acetabuli	0.575	0.425	0.000
M24.6 Ankylosis of joint	0.575	0.425	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.427	0.573
M24.5 Contracture of joint	0.569	0.431	0.000
M20.2 Hallux rigidus	0.569	0.431	0.000
M48.8 Other specified spondylopathies	0.568	0.431	0.000
K81.9 Cholecystitis, unspecified	0.567	0.433	0.000
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)	0.566	0.434	0.000
M25.3 Other instability of joint	0.564	0.436	0.000
M25.8 Other specified joint disorders	0.562	0.438	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.439	0.561
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.555	0.445	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.445	0.555
M47.87 Other spondylosis (Lumbosacral region)	0.554	0.446	0.000
M25.0 Haemarthrosis	0.554	0.446	0.000
M24.02 Loose body in joint (Upper arm)	0.553	0.447	0.000
M77.9 Enthesopathy, unspecified	0.553	0.447	0.000
M77.02 Medial epicondylitis (Upper arm)	0.553	0.447	0.000
M47.89 Other spondylosis (Site unspecified)	0.552	0.448	0.000
M71 Other bursopathies	0.552	0.448	0.000
M43.9 Deforming dorsopathy, unspecified	0.552	0.448	0.000
M43.8 Other specified deforming dorsopathies	0.552	0.448	0.000
M43.6 Torticollis	0.552	0.448	0.000
M43.5 Other recurrent vertebral subluxation	0.552	0.448	0.000
M43.4 Other recurrent atlantoaxial subluxation	0.552	0.448	0.000
M43.3 Recurrent atlantoaxial subluxation with myelopathy	0.552	0.448	0.000
M79.1 Myalgia	0.550	0.450	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.549	0.451	0.000
M34.0 Progressive systemic sclerosis	0.549	0.451	0.000
M79.09 Rheumatism, unspecified (Site unspecified)	0.549	0.451	0.000
K86 Other diseases of pancreas	0.547	0.453	0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.547	0.453	0.000
M70.2 Olecranon bursitis	0.545	0.454	0.000
M79.4 Hypertrophy of (infrapatellar) fat pad	0.545	0.454	0.000
M24.1 Other articular cartilage disorders	0.543	0.457	0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.542	0.458	0.000
M79.7 Fibromyalgia	0.541	0.459	0.000
M70.9 Unspecified soft tissue disorder related to use, overuse and pressure	0.541	0.459	0.000
M70.8 Other soft tissue disorders related to use, overuse and pressure	0.541	0.459	0.000
M70.7 Other bursitis of hip	0.541	0.459	0.000
M70.5 Other bursitis of knee	0.541	0.459	0.000
M70.3 Other bursitis of elbow	0.541	0.459	0.000
M70.1 Bursitis of hand	0.541	0.459	0.000
M70.0 Chronic crepitant synovitis of hand and wrist	0.541	0.459	0.000
M21.1 Varus deformity, not elsewhere classified	0.540	0.460	0.000
K80.0 Calculus of gallbladder with acute cholecystitis	0.538	0.462	0.000
M89.3 Hypertrophy of bone	0.538	0.462	0.000
M21.26 Flexion deformity (Lower leg)	0.537	0.463	0.000
M87 Osteonecrosis	0.537	0.463	0.000
M45 Ankylosing spondylitis	0.536	0.464	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.535	0.465	0.000
K83.8 Other specified diseases of biliary tract	0.534	0.466	0.000
M49 Spondylopathies in diseases classified elsewhere	0.533	0.467	0.000
M24.09 Loose body in joint (Site unspecified)	0.533	0.467	0.000
M24.08 Loose body in joint (Other)	0.533	0.467	0.000
M24.06 Loose body in joint-Lower leg	0.533	0.467	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.533	0.467	0.000
M24.04 Loose body in joint (Hand)	0.533	0.467	0.000
M24.03 Loose body in joint (Forearm)	0.533	0.467	0.000
M24.01 Loose body in joint (Shoulder region)	0.533	0.467	0.000
M24.00 Loose body in joint (Multiple sites)	0.533	0.467	0.000
M43.16 Spondylolisthesis (Lumbar region)	0.533	0.467	0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.532	0.468	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.531	0.469	0.000
M79.9 Soft tissue disorder, unspecified	0.530	0.470	0.000
M76 Enthesopathies of lower limb, excluding foot	0.529	0.470	0.000
M70.4 Prepatellar bursitis	0.529	0.471	0.000
M89.87 Other specified disorders of bone (Ankle and foot)	0.528	0.472	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.000	0.472	0.527
M47.84 Other spondylosis (Thoracic region)	0.524	0.475	0.000
M79.3 Panniculitis, unspecified	0.521	0.479	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.521	0.479	0.000
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)	0.520	0.480	0.000
M43.15 Spondylolisthesis (Thoracolumbar region)	0.520	0.480	0.000
M43.14 Spondylolisthesis (Thoracic region)	0.520	0.480	0.000
M43.13 Spondylolisthesis (Cervicothoracic region)	0.520	0.480	0.000
M43.12 Spondylolisthesis (Cervical region)	0.520	0.480	0.000
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)	0.520	0.480	0.000
M43.10 Spondylolisthesis (Multiple sites in spine)	0.520	0.480	0.000
K80.2 Calculus of gallbladder without cholecystitis	0.518	0.482	0.000
M47.0 Anterior spinal and vertebral artery compression syndromes	0.516	0.484	0.000
M89.81 Other specified disorders of bone (Shoulder region)	0.514	0.485	0.000
M79.54 Residual foreign body in soft tissue (Hand)	0.514	0.486	0.000
I23.8 Other current complications following acute myocardial infarction	0.000	0.486	0.514
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.486	0.514
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.486	0.514
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.486	0.514
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.486	0.514
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.486	0.514
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.486	0.514
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.486	0.514
M77.8 Other enthesopathies, not elsewhere classified	0.514	0.486	0.000
M77.3 Calcaneal spur	0.514	0.486	0.000
M77.2 Periarthritis of wrist	0.514	0.486	0.000
M70.69 Trochanteric bursitis-Site unspec	0.510	0.490	0.000
M70.68 Trochanteric bursitis-Other	0.510	0.490	0.000
M70.67 Trochanteric bursitis-Ankle/Foot	0.510	0.490	0.000
M70.66 Trochanteric bursitis-Lower Leg	0.510	0.490	0.000
M70.64 Trochanteric bursitis-Hand	0.510	0.490	0.000
M70.63 Trochanteric bursitis-Forearm	0.510	0.490	0.000
M70.62 Trochanteric bursitis-Upper arm	0.510	0.490	0.000
M70.61 Trochanteric bursitis-Shldr region	0.510	0.490	0.000
M70.60 Trochanteric bursitis-Mult sites	0.510	0.490	0.000
K83.0 Cholangitis	0.510	0.490	0.000
M40.29 Other and unspecified kyphosis (Site unspecified)	0.509	0.491	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.509	0.491	0.000
M24.26 Disorder of ligament (Lower leg)	0.506	0.493	0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.506	0.494	0.000
M79.2 Neuralgia and neuritis, unspecified	0.502	0.498	0.000
M25.2 Flail joint	0.502	0.498	0.000
M25.1 Fistula of joint	0.502	0.498	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.501	0.499	0.000
M43.29 Other fusion of spine (Site unspecified)	0.500	0.500	0.000
M72.9 Fibroblastic disorder, unspecified	0.498	0.501	0.000
M72.8 Other fibroblastic disorders	0.498	0.501	0.000
M72.6 Necrotizing fasciitis	0.498	0.501	0.000
M72.5 Fasciitis, not elsewhere classified	0.498	0.501	0.000
M72.4 Pseudosarcomatous fibromatosis	0.498	0.501	0.000
M72.3 Nodular fasciitis	0.498	0.501	0.000
M72.1 Knuckle pads	0.498	0.501	0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)	0.498	0.502	0.000
M21.39 Wrist or foot drop (acquired)-Site unspec	0.497	0.502	0.000
M21.38 Wrist or foot drop (acquired)-Other	0.497	0.502	0.000
M21.36 Wrist or foot drop (acquired)-Lower leg	0.497	0.502	0.000
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.497	0.502	0.000
M21.34 Wrist or foot drop (acquired) (Hand)	0.497	0.502	0.000
M21.33 Wrist or foot drop (acquired) (Forearm)	0.497	0.502	0.000
M21.32 Wrist or foot drop (acquired)-Upper arm	0.497	0.502	0.000
M21.31 Wrist or foot drop (acquired)-Shldr region	0.497	0.502	0.000
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.497	0.502	0.000
K86.2 Cyst of pancreas	0.497	0.503	0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)	0.496	0.504	0.000
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.494	0.506	0.000
M21.08 Valgus deformity, not elsewhere classified (Other)	0.494	0.506	0.000
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.494	0.506	0.000
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.494	0.506	0.000
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.494	0.506	0.000
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.494	0.506	0.000
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.494	0.506	0.000
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.494	0.506	0.000
M77.47 Metatarsalgia-Ankle/Foot	0.492	0.508	0.000
M82.1 Osteoporosis in endocrine disorders	0.491	0.508	0.000
M41 Scoliosis	0.490	0.509	0.000
M47.29 Other spondylosis with radiculopathy (Site unspecified)	0.490	0.510	0.000
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)	0.490	0.510	0.000
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)	0.490	0.510	0.000
M47.24 Other spondylosis with radiculopathy (Thoracic region)	0.490	0.510	0.000
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)	0.490	0.510	0.000
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)	0.490	0.510	0.000
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)	0.490	0.510	0.000
M89.6 Osteopathy after poliomyelitis	0.490	0.510	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.490	0.510	0.000
M89.2 Other disorders of bone development and growth	0.490	0.510	0.000
M89.1 Epiphyseal arrest	0.490	0.510	0.000
M90 Osteopathies in diseases classified elsewhere	0.489	0.511	0.000
M48.87 Other specified spondylopathies (Lumbosacral region)	0.489	0.511	0.000
K80.4 Calculus of bile duct with cholecystitis	0.488	0.512	0.000
M48.9 Spondylopathy, unspecified	0.487	0.513	0.000
M48.4 Fatigue fracture of vertebra	0.487	0.513	0.000
M48.3 Traumatic spondylopathy	0.487	0.513	0.000
M48.2 Kissing spine	0.487	0.513	0.000
M48.1 Ankylosing hyperostosis [Forestier]	0.487	0.513	0.000
M21.24 Flexion deformity (Hand)	0.486	0.513	0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.486	0.514	0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.486	0.514	0.000
M40.5 Lordosis, unspecified	0.486	0.514	0.000
M40.4 Other lordosis	0.486	0.514	0.000
M40.3 Flatback syndrome	0.486	0.514	0.000
M40.1 Other secondary kyphosis	0.486	0.514	0.000
M40.0 Postural kyphosis	0.486	0.514	0.000
M79.82 Other specified soft tissue disorders (Upper arm)	0.484	0.516	0.000
M00 Pyogenic arthritis	0.483	0.517	0.000
K86.8 Other specified diseases of pancreas	0.483	0.517	0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.482	0.517	0.000
M36.3 Arthropathy in other blood disorders	0.482	0.517	0.000
M36.2 Haemophilic arthropathy	0.482	0.517	0.000
M36.1 Arthropathy in neoplastic disease	0.482	0.517	0.000
M36.0 Dermato(poly)myositis in neoplastic disease	0.482	0.517	0.000
M77.5 Other enthesopathy of foot	0.482	0.518	0.000
M21.99 Acquired deformity of limb, unspecified (Site unspecified)	0.481	0.519	0.000
M21.98 Acquired deformity of limb, unspecified-Other	0.481	0.519	0.000
M21.96 Acquired deformity of limb, unspecified (Lower leg)	0.481	0.519	0.000
M21.95 Acquired deformity of limb, unspecified (Pelvic region and thigh)	0.481	0.519	0.000
M21.94 Acquired deformity of limb, unspecified (Hand)	0.481	0.519	0.000
M21.93 Acquired deformity of limb, unspecified (Forearm)	0.481	0.519	0.000
M21.92 Acquired deformity of limb, unspecified (Upper arm)	0.481	0.519	0.000
M21.91 Acquired deformity of limb, unspecified (Shoulder region)	0.481	0.519	0.000
M21.90 Acquired deformity of limb, unspecified (Multiple sites)	0.481	0.519	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.480	0.520	0.000
M85.9 Disorder of bone density and structure, unspecified	0.479	0.521	0.000
M85.5 Aneurysmal bone cyst	0.479	0.521	0.000
M85.4 Solitary bone cyst	0.479	0.521	0.000
M85.3 Osteitis condensans	0.479	0.521	0.000
M85.2 Hyperostosis of skull	0.479	0.521	0.000
M85.1 Skeletal fluorosis	0.479	0.521	0.000
M79.83 Other specified soft tissue disorders (Forearm)	0.479	0.521	0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.478	0.521	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.478	0.521	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.478	0.521	0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.478	0.521	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.478	0.521	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.478	0.521	0.000
M25.81 Other specified joint disorders (Shoulder region)	0.478	0.522	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.476	0.524	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.476	0.524	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.476	0.524	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.476	0.524	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.476	0.524	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.476	0.524	0.000
M89.03 Algoneurodystrophy (Forearm)	0.476	0.524	0.000
M47.1 Other spondylosis with myelopathy	0.476	0.524	0.000
M86.9 Osteomyelitis, unspecified	0.473	0.527	0.000
M79.86 Other specified soft tissue disorders (Lower leg)	0.473	0.527	0.000
M21.29 Flexion deformity (Site unspecified)	0.472	0.528	0.000
M21.28 Flexion deformity (Other)	0.472	0.528	0.000
M21.25 Flexion deformity (Pelvic region and thigh)	0.472	0.528	0.000
M21.23 Flexion deformity (Forearm)	0.472	0.528	0.000
M21.22 Flexion deformity (Upper arm)	0.472	0.528	0.000
M21.21 Flexion deformity (Shoulder region)	0.472	0.528	0.000
M21.20 Flexion deformity (Multiple sites)	0.472	0.528	0.000
M89.5 Osteolysis	0.471	0.529	0.000
M77.97 Enthesopathy, unspecified (Ankle and foot)	0.471	0.529	0.000
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns	0.471	0.529	0.000
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other	0.471	0.529	0.000
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le	0.471	0.529	0.000
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t	0.471	0.529	0.000
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.471	0.529	0.000
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm	0.471	0.529	0.000
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar	0.471	0.529	0.000
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re	0.471	0.529	0.000
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)	0.471	0.529	0.000
M25.83 Other specified joint disorders (Forearm)	0.471	0.529	0.000
M21.27 Flexion deformity (Ankle and foot)	0.469	0.530	0.000
M43.19 Spondylolisthesis (Site unspecified)	0.467	0.533	0.000
M24.24 Disorder of ligament (Hand)	0.465	0.535	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.465	0.535	0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.464	0.536	0.000
M79.84 Other specified soft tissue disorders (Hand)	0.464	0.536	0.000
M77.1 Lateral epicondylitis	0.462	0.537	0.000
M43.02 Spondylolysis (Cervical region)	0.462	0.538	0.000
M89.06 Algoneurodystrophy (Lower leg)	0.461	0.538	0.000
M82.8 Osteoporosis in other diseases classified elsewhere	0.461	0.539	0.000
M82.0 Osteoporosis in multiple myelomatosis	0.461	0.539	0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.461	0.539	0.000
M24.29 Disorder of ligament (Site unspecified)	0.460	0.539	0.000
M24.28 Disorder of ligament (Other)	0.460	0.539	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.460	0.539	0.000
M24.22 Disorder of ligament (Upper arm)	0.460	0.539	0.000
M24.21 Disorder of ligament (Shoulder region)	0.460	0.539	0.000
M24.20 Disorder of ligament (Multiple sites)	0.460	0.539	0.000
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.459	0.541	0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.457	0.543	0.000
M02 Reactive arthropathies	0.457	0.543	0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.457	0.543	0.000
M60 Myositis	0.456	0.544	0.000
K86.1 Other chronic pancreatitis	0.456	0.544	0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.455	0.545	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.455	0.545	0.000
M25.9 Joint disorder, unspecified	0.455	0.545	0.000
M48.0 Spinal stenosis	0.454	0.546	0.000
M25.33 Other instability of joint (Forearm)	0.452	0.548	0.000
M72.29 Plantar fascial fibromatosis-Site unspec	0.452	0.548	0.000
M72.28 Plantar fascial fibromatosis-Other	0.452	0.548	0.000
M72.26 Plantar fascial fibromatosis-Lower Leg	0.452	0.548	0.000
M72.25 Plantar fascial fibromatosis-Pelvic/Thigh	0.452	0.548	0.000
M72.24 Plantar fascial fibromatosis-Hand	0.452	0.548	0.000
M72.23 Plantar fascial fibromatosis-Forearm	0.452	0.548	0.000
M72.22 Plantar fascial fibromatosis-Upper arm	0.452	0.548	0.000
M72.21 Plantar fascial fibromatosis-Shldr region	0.452	0.548	0.000
M72.20 Plantar fascial fibromatosis-Mult sites	0.452	0.548	0.000
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)	0.452	0.548	0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.451	0.549	0.000
M47.85 Other spondylosis (Thoracolumbar region)	0.451	0.549	0.000
M47.83 Other spondylosis (Cervicothoracic region)	0.451	0.549	0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.451	0.549	0.000
M79.19 Myalgia (Site unspecified)	0.451	0.549	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.450	0.550	0.000
M25.06 Haemarthrosis (Lower leg)	0.449	0.551	0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.449	0.551	0.000
M81.49 Drug-induced osteoporosis (Site unspecified)	0.448	0.552	0.000
M81.48 Drug-induced osteoporosis (Other)	0.448	0.552	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.448	0.552	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.448	0.552	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.448	0.552	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.448	0.552	0.000
M81.43 Drug-induced osteoporosis (Forearm)	0.448	0.552	0.000
M81.42 Drug-induced osteoporosis (Upper arm)	0.448	0.552	0.000
M81.41 Drug-induced osteoporosis (Shoulder region)	0.448	0.552	0.000
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)	0.447	0.553	0.000
M84.0 Malunion of fracture	0.446	0.554	0.000
M77.09 Medial epicondylitis (Site unspecified)	0.445	0.554	0.000
M77.08 Medial epicondylitis-Other	0.445	0.554	0.000
M77.07 Medial epicondylitis-Ankle/Foot	0.445	0.554	0.000
M77.06 Medial epicondylitis (Lower leg)	0.445	0.554	0.000
M77.05 Medial epicondylitis (Pelvic region and thigh)	0.445	0.554	0.000
M77.04 Medial epicondylitis-Hand	0.445	0.554	0.000
M77.03 Medial epicondylitis-Forearm	0.445	0.554	0.000
M77.01 Medial epicondylitis-Shldr region	0.445	0.554	0.000
M77.00 Medial epicondylitis (Multiple sites)	0.445	0.554	0.000
M24.56 Contracture of joint (Lower leg)	0.445	0.555	0.000
M94 Other disorders of cartilage	0.445	0.555	0.000
M47.80 Other spondylosis (Multiple sites in spine)	0.445	0.555	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.444	0.556	0.000
M88 Paget's disease of bone [osteitis deformans]	0.443	0.556	0.001
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.443	0.557	0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.443	0.557	0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.443	0.557	0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.443	0.557	0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.443	0.557	0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.443	0.557	0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.443	0.557	0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.443	0.557	0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.443	0.557	0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.443	0.557	0.000
M47.86 Other spondylosis (Lumbar region)	0.443	0.557	0.000
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.442	0.558	0.000
M81.08 Postmenopausal osteoporosis (Other)	0.442	0.558	0.000
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.442	0.558	0.000
M81.06 Postmenopausal osteoporosis (Lower leg)	0.442	0.558	0.000
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.442	0.558	0.000
M81.04 Postmenopausal osteoporosis (Hand)	0.442	0.558	0.000
M81.03 Postmenopausal osteoporosis (Forearm)	0.442	0.558	0.000
M81.02 Postmenopausal osteoporosis (Upper arm)	0.442	0.558	0.000
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.442	0.558	0.000
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.442	0.558	0.000
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.442	0.558	0.000
M81.18 Postoophorectomy osteoporosis (Other)	0.442	0.558	0.000
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.442	0.558	0.000
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.442	0.558	0.000
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.442	0.558	0.000
M81.14 Postoophorectomy osteoporosis (Hand)	0.442	0.558	0.000
M81.13 Postoophorectomy osteoporosis (Forearm)	0.442	0.558	0.000
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.442	0.558	0.000
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.442	0.558	0.000
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.442	0.558	0.000
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.442	0.558	0.000
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.442	0.558	0.000
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.442	0.558	0.000
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.442	0.558	0.000
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.442	0.558	0.000
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.442	0.558	0.000
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.442	0.558	0.000
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.442	0.558	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations