TreeWAS – Variant ID: rs79570361

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
I25.1 Atherosclerotic heart disease	1.000	0.000
Z95.1 Presence of aortocoronary bypass graft	1.000	0.000
I25 Chronic ischaemic heart disease	1.000	0.000
I20 Angina pectoris	1.000	0.000
Z95 Presence of cardiac and vascular implants and grafts	1.000	0.000
I20-I25 Ischaemic heart diseases	1.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000
# Top node	1.000	0.000
I25.8 Other forms of chronic ischaemic heart disease	1.000	0.000
I20.9 Angina pectoris, unspecified	1.000	0.000
I25.2 Old myocardial infarction	1.000	0.000
I25.9 Chronic ischaemic heart disease, unspecified	1.000	0.000
I20.0 Unstable angina	1.000	0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	1.000	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	1.000	0.000
Chapter II Neoplasms	0.999	0.001
Chapter XX External causes of morbidity and mortality	0.998	0.002
Z95.5 Presence of coronary angioplasty implant and graft	0.997	0.003
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.997	0.003
I30-I52 Other forms of heart disease	0.997	0.003
C15-C26 Malignant neoplasms of digestive organs	0.997	0.003
Chapter XXI Factors influencing health status and contact with health services	0.996	0.004
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.995	0.005
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.995	0.005
C18 Malignant neoplasm of colon	0.995	0.005
E78.0 Pure hypercholesterolaemia	0.993	0.007
Chapter IV Endocrine, nutritional and metabolic diseases	0.992	0.008
E70-E90 Metabolic disorders	0.991	0.009
Chapter I Certain infectious and parasitic diseases	0.990	0.010
I22 Subsequent myocardial infarction	0.990	0.010
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.989	0.011
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.988	0.012
Z70-Z76 Persons encountering health services in other circumstances	0.988	0.012
I35 Nonrheumatic aortic valve disorders	0.987	0.013
B95-B98 Bacterial, viral and other infectious agents	0.986	0.014
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.985	0.015
Z95.4 Presence of other heart-valve replacement	0.985	0.015
I74 Arterial embolism and thrombosis	0.983	0.017
I10-I15 Hypertensive diseases	0.982	0.018
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.979	0.021
I20.8 Other forms of angina pectoris	0.978	0.022
Z95.2 Presence of prosthetic heart valve	0.976	0.024
E78.5 Hyperlipidaemia, unspecified	0.976	0.024
I10 Essential (primary) hypertension	0.975	0.025
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.975	0.025
S60-S69 Injuries to the wrist and hand	0.974	0.026
I22.9 Subsequent myocardial infarction of unspecified site	0.974	0.026
S62 Fracture at wrist and hand level	0.974	0.026
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.973	0.027
Y83.2 Surgical operation with anastomosis, bypass or graft	0.972	0.028
I72 Other aneurysm	0.969	0.031
C18.0 Caecum	0.968	0.032
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.964	0.036
Z71.8 Other specified counselling	0.959	0.041
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.959	0.041
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.958	0.042
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.955	0.045
I31 Other diseases of pericardium	0.948	0.052
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.939	0.061
I71 Aortic aneurysm and dissection	0.939	0.061
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.938	0.062
E20-E35 Disorders of other endocrine glands	0.937	0.063
I34 Nonrheumatic mitral valve disorders	0.933	0.067
S62.6 Fracture of other finger	0.931	0.069
I72.4 Aneurysm of artery of lower extremity	0.929	0.071
C18.9 Colon, unspecified	0.929	0.071
T93 Sequelae of injuries of lower limb	0.928	0.072
B99-B99 Other infectious diseases	0.928	0.072
Z95.0 Presence of cardiac pacemaker	0.928	0.072
Z93 Artificial opening status	0.923	0.077
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.921	0.079
I35.0 Aortic (valve) stenosis	0.921	0.079
S62.5 Fracture of thumb	0.920	0.080
I25.5 Ischaemic cardiomyopathy	0.918	0.082
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.914	0.086
Z71.3 Dietary counselling and surveillance	0.913	0.087
I21 Acute myocardial infarction	0.912	0.088
I45 Other conduction disorders	0.910	0.090
S62.61 Fracture of other finger (open)	0.910	0.090
I73 Other peripheral vascular diseases	0.905	0.095
C16 Malignant neoplasm of stomach	0.904	0.096
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.899	0.101
E78.2 Mixed hyperlipidaemia	0.896	0.104
C73 Malignant neoplasm of thyroid gland	0.894	0.106
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.894	0.106
C18.5 Splenic flexure	0.891	0.109
C18.7 Sigmoid colon	0.890	0.110
I35.2 Aortic (valve) stenosis with insufficiency	0.886	0.114
S62.3 Fracture of other metacarpal bone	0.884	0.116
B99 Other and unspecified infectious diseases	0.883	0.117
Z99.2 Dependence on renal dialysis	0.879	0.121
I22.1 Subsequent myocardial infarction of inferior wall	0.875	0.125
C51-C58 Malignant neoplasms of female genital organs	0.874	0.126
I31.3 Pericardial effusion (noninflammatory)	0.874	0.126
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.874	0.126
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.873	0.127
Y83.4 Other reconstructive surgery	0.870	0.130
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.868	0.132
T82.0 Mechanical complication of heart valve prosthesis	0.866	0.134
T93.8 Sequelae of other specified injuries of lower limb	0.861	0.139
I35.8 Other aortic valve disorders	0.861	0.139
E80 Disorders of porphyrin and bilirubin metabolism	0.861	0.139
V40-V49 Car occupant injured in transport accident	0.858	0.142
Chapter XXII Codes for special purposes	0.858	0.142
S62.7 Multiple fractures of fingers	0.856	0.144
Z75 Problems related to medical facilities and other health care	0.855	0.145
T20-T25 Burns and corrosions of external body surface, specified by site	0.854	0.145
Chapter VIII Diseases of the ear and mastoid process	0.853	0.147
E22 Hyperfunction of pituitary gland	0.851	0.149
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.850	0.150
D00-D09 In situ neoplasms	0.845	0.155
C34 Malignant neoplasm of bronchus and lung	0.844	0.156
Z73 Problems related to life-management difficulty	0.844	0.156
I35.9 Aortic valve disorder, unspecified	0.844	0.156
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.839	0.161
I34.1 Mitral (valve) prolapse	0.839	0.161
X58-X59 Accidental exposure to other and unspecified factors	0.839	0.161
I73.0 Raynaud's syndrome	0.839	0.161
C18.1 Appendix	0.838	0.162
E73 Lactose intolerance	0.837	0.163
I24 Other acute ischaemic heart diseases	0.836	0.164
I74.5 Embolism and thrombosis of iliac artery	0.835	0.165
Z93.6 Other artificial openings of urinary tract status	0.831	0.169
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.831	0.169
I33 Acute and subacute endocarditis	0.829	0.171
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.827	0.173
I31.9 Disease of pericardium, unspecified	0.823	0.177
B97 Viral agents as the cause of diseases classified to other chapters	0.821	0.179
Z95.3 Presence of xenogenic heart valve	0.821	0.179
S62.50 Fracture of thumb (closed)	0.820	0.180
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.819	0.181
S62.51 Fracture of thumb (open)	0.818	0.182
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.818	0.182
I72.0 Aneurysm of carotid artery	0.817	0.183
X60-X84 Intentional self-harm	0.813	0.187
C71 Malignant neoplasm of brain	0.809	0.191
I45.8 Other specified conduction disorders	0.808	0.192
I45.5 Other specified heart block	0.807	0.193
S62.30 Fracture of other metacarpal bone (closed)	0.807	0.193
I34.0 Mitral (valve) insufficiency	0.806	0.194
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.806	0.194
C19 Malignant neoplasm of rectosigmoid junction	0.806	0.194
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.806	0.194
E27 Other disorders of adrenal gland	0.804	0.196
T82.1 Mechanical complication of cardiac electronic device	0.804	0.196
C40-C41 Malignant neoplasms of bone and articular cartilage	0.801	0.199
H80-H83 Diseases of inner ear	0.798	0.202
C17 Malignant neoplasm of small intestine	0.798	0.202
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.798	0.202
C34.1 Upper lobe, bronchus or lung	0.798	0.202
Y84.1 Kidney dialysis	0.796	0.204
Y00-Y09 Assault	0.794	0.206
Z82.1 Family history of blindness and visual loss	0.793	0.207
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.793	0.207
I21.4 Acute subendocardial myocardial infarction	0.793	0.207
X50-X57 Overexertion, travel and privation	0.793	0.207
C21 Malignant neoplasm of anus and anal canal	0.791	0.209
Y60-Y69 Misadventures to patients during surgical and medical care	0.791	0.209
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.790	0.210
E23 Hypofunction and other disorders of pituitary gland	0.789	0.211
Z93.0 Tracheostomy status	0.788	0.212
Z76 Persons encountering health services in other circumstances	0.787	0.213
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue	0.787	0.213
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.787	0.213
Z73.3 Stress, not elsewhere classified	0.783	0.217
I72.2 Aneurysm of renal artery	0.783	0.217
V10-V19 Pedal cyclist injured in transport accident	0.781	0.219
I25.0 Atherosclerotic cardiovascular disease, so described	0.779	0.221
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.779	0.221
T81 Complications of procedures, not elsewhere classified	0.778	0.222
C16.9 Stomach, unspecified	0.777	0.223
C54 Malignant neoplasm of corpus uteri	0.777	0.223
W50-W64 Exposure to animate mechanical forces	0.776	0.224
T92 Sequelae of injuries of upper limb	0.775	0.225
I70 Atherosclerosis	0.775	0.225
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.774	0.225
E78.9 Disorder of lipoprotein metabolism, unspecified	0.774	0.226
H83 Other diseases of inner ear	0.773	0.227
I21.9 Acute myocardial infarction, unspecified	0.772	0.228
S62.70 Multiple fractures of fingers (closed)	0.772	0.228
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.769	0.231
V01-V09 Pedestrian injured in transport accident	0.768	0.232
E80.4 Gilbert's syndrome	0.768	0.232
V20-V29 Motorcycle rider injured in transport accident	0.765	0.235
S62.1 Fracture of other carpal bone(s)	0.765	0.235
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.762	0.238
E78.4 Other hyperlipidaemia	0.759	0.241
C18.3 Hepatic flexure	0.759	0.241
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.755	0.245
H83.0 Labyrinthitis	0.755	0.245
I24.8 Other forms of acute ischaemic heart disease	0.754	0.246
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.754	0.246
I05-I09 Chronic rheumatic heart diseases	0.753	0.247
S62.2 Fracture of first metacarpal bone	0.752	0.248
T85 Complications of other internal prosthetic devices, implants and grafts	0.752	0.248
I25.4 Coronary artery aneurysm	0.751	0.249
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.749	0.251
W75-W84 Other accidental threats to breathing	0.749	0.251
T93.1 Sequelae of fracture of femur	0.747	0.253
B90-B94 Sequelae of infectious and parasitic diseases	0.747	0.253
I46 Cardiac arrest	0.746	0.254
C71.9 Brain, unspecified	0.746	0.254
V98-V99 Other and unspecified transport accidents	0.745	0.255
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters	0.744	0.256
T82.3 Mechanical complication of other vascular grafts	0.744	0.256
E22.0 Acromegaly and pituitary gigantism	0.742	0.258
S70-S79 Injuries to the hip and thigh	0.741	0.259
Y83.1 Surgical operation with implant of artificial internal device	0.741	0.259
Y83.5 Amputation of limb(s)	0.740	0.260
Z84 Family history of other conditions	0.739	0.261
I38 Endocarditis, valve unspecified	0.739	0.261
I11 Hypertensive heart disease	0.737	0.263
Z99.8 Dependence on other enabling machines and devices	0.737	0.263
X20-X29 Contact with venomous animals and plants	0.736	0.264
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.734	0.266
B50-B64 Protozoal diseases	0.733	0.267
C34.3 Lower lobe, bronchus or lung	0.731	0.269
C16.3 Pyloric antrum	0.731	0.269
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.730	0.269
A65-A69 Other spirochaetal diseases	0.729	0.271
T90 Sequelae of injuries of head	0.728	0.272
E85 Amyloidosis	0.728	0.272
E73.9 Lactose intolerance, unspecified	0.727	0.273
C53 Malignant neoplasm of cervix uteri	0.727	0.273
D05 Carcinoma in situ of breast	0.727	0.273
D37-D48 Neoplasms of uncertain or unknown behaviour	0.726	0.274
A80-A89 Viral infections of the central nervous system	0.725	0.275
T87 Complications peculiar to reattachment and amputation	0.723	0.277
Z81 Family history of mental and behavioural disorders	0.722	0.278
Z29 Need for other prophylactic measures	0.722	0.278
T79-T79 Certain early complications of trauma	0.721	0.279
Z93.5 Cystostomy status	0.721	0.279
X10-X19 Contact with heat and hot substances	0.720	0.280
I22.8 Subsequent myocardial infarction of other sites	0.720	0.280
Z75.8 Other problems related to medical facilities and other health care	0.720	0.280
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.719	0.281
Z93.4 Other artificial openings of gastro-intestinal tract status	0.718	0.282
T80 Complications following infusion, transfusion and therapeutic injection	0.717	0.283
I25.6 Silent myocardial ischaemia	0.717	0.283
I23 Certain current complications following acute myocardial infarction	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.716	0.284
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.716	0.284
Z82.5 Family history of asthma and other chronic lower respiratory diseases	0.716	0.284
I45.6 Preexcitation syndrome	0.716	0.284
Y35-Y36 Legal intervention and operations of war	0.716	0.284
Y10-Y34 Event of undetermined intent	0.716	0.284
X85-X99 Assault	0.716	0.284
X30-X39 Exposure to forces of nature	0.716	0.284
X00-X09 Exposure to smoke, fire and flames	0.716	0.284
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.716	0.284
W65-W74 Accidental drowning and submersion	0.716	0.284
V95-V97 Air and space transport accidents	0.716	0.284
V90-V94 Water transport accidents	0.716	0.284
V70-V79 Bus occupant injured in transport accident	0.716	0.284
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.716	0.284
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.716	0.284
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.716	0.284
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.715	0.285
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified	0.715	0.285
Z82.2 Family history of deafness and hearing loss	0.715	0.285
C26 Malignant neoplasm of other and ill-defined digestive organs	0.715	0.285
I52 Other heart disorders in diseases classified elsewhere	0.715	0.285
I48 Atrial fibrillation and flutter	0.715	0.285
I43 Cardiomyopathy in diseases classified elsewhere	0.715	0.285
I41 Myocarditis in diseases classified elsewhere	0.715	0.285
I40 Acute myocarditis	0.715	0.285
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.715	0.285
I32 Pericarditis in diseases classified elsewhere	0.715	0.285
A30-A49 Other bacterial diseases	0.714	0.286
I74.8 Embolism and thrombosis of other arteries	0.714	0.286
E78.8 Other disorders of lipoprotein metabolism	0.713	0.286
E78.6 Lipoprotein deficiency	0.713	0.287
E78.3 Hyperchylomicronaemia	0.713	0.287
C18.8 Overlapping lesion of colon	0.713	0.287
Z75.5 Holiday relief care	0.712	0.288
E27.8 Other specified disorders of adrenal gland	0.711	0.289
Y84.8 Other medical procedures	0.711	0.289
E84 Cystic fibrosis	0.710	0.290
E79 Disorders of purine and pyrimidine metabolism	0.710	0.290
E77 Disorders of glycoprotein metabolism	0.710	0.290
E76 Disorders of glycosaminoglycan metabolism	0.710	0.290
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.710	0.290
E72 Other disorders of amino-acid metabolism	0.710	0.290
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.710	0.290
E70 Disorders of aromatic amino-acid metabolism	0.710	0.290
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.710	0.290
B85-B89 Pediculosis, acariasis and other infestations	0.710	0.290
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.710	0.290
A75-A79 Rickettsioses	0.710	0.290
A70-A74 Other diseases caused by chlamydiae	0.710	0.290
A20-A28 Certain zoonotic bacterial diseases	0.710	0.290
A15-A19 Tuberculosis	0.710	0.290
I33.0 Acute and subacute infective endocarditis	0.709	0.291
T33-T35 Frostbite	0.709	0.291
T26-T28 Burns and corrosions confined to eye and internal organs	0.709	0.291
T00-T07 Injuries involving multiple body regions	0.709	0.291
Z70 Counselling related to sexual attitude, behaviour and orientation	0.708	0.292
C54.1 Endometrium	0.707	0.293
Z89 Acquired absence of limb	0.707	0.293
C16.0 Cardia	0.707	0.293
I71.3 Abdominal aortic aneurysm, ruptured	0.706	0.294
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified	0.706	0.294
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.705	0.295
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.705	0.295
I74.0 Embolism and thrombosis of abdominal aorta	0.705	0.295
S90-S99 Injuries to the ankle and foot	0.705	0.295
S62.8 Fracture of other and unspecified parts of wrist and hand	0.705	0.295
C32 Malignant neoplasm of larynx	0.704	0.295
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.704	0.296
I13 Hypertensive heart and renal disease	0.704	0.296
Z71.1 Person with feared complaint in whom no diagnosis is made	0.704	0.296
H60-H62 Diseases of external ear	0.701	0.299
I15 Secondary hypertension	0.701	0.299
I45.2 Bifascicular block	0.701	0.299
C83 Diffuse non-Hodgkin's lymphoma	0.701	0.299
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.700	0.300
S65 Injury of blood vessels at wrist and hand level	0.700	0.300
I72.3 Aneurysm of iliac artery	0.700	0.300
V49 Car occupant injured in other and unspecified transport accidents	0.700	0.300
T81.9 Unspecified complication of procedure	0.699	0.301
Z71.7 Human immunodeficiency virus [HIV] counselling	0.699	0.301
Z71.5 Drug abuse counselling and surveillance	0.699	0.301
Z71.4 Alcohol abuse counselling and surveillance	0.699	0.301
Z71.0 Person consulting on behalf of another person	0.699	0.301
C69 Malignant neoplasm of eye and adnexa	0.698	0.301
T88 Other complications of surgical and medical care, not elsewhere classified	0.698	0.302
S62.4 Multiple fractures of metacarpal bones	0.697	0.303
S69 Other and unspecified injuries of wrist and hand	0.697	0.303
I72.9 Aneurysm of unspecified site	0.695	0.305
I72.6 Aneurysm and dissection of vertebral artery	0.695	0.305
I72.5 Aneurysm and dissection of other precerebral arteries	0.695	0.305
I72.1 Aneurysm of artery of upper extremity	0.695	0.305
Z93.8 Other artificial opening status	0.695	0.305
Z93.3 Colostomy status	0.694	0.306
C20 Malignant neoplasm of rectum	0.694	0.306
C30 Malignant neoplasm of nasal cavity and middle ear	0.693	0.307
E26 Hyperaldosteronism	0.693	0.307
Y44 Agents primarily affecting blood constituents	0.693	0.307
I73.8 Other specified peripheral vascular diseases	0.693	0.307
S40-S49 Injuries to the shoulder and upper arm	0.692	0.308
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.692	0.308
T94 Sequelae of injuries involving multiple and unspecified body regions	0.691	0.308
Y41 Other systemic anti-infectives and antiparasitics	0.690	0.310
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.690	0.310
T23 Burn and corrosion of wrist and hand	0.689	0.311
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.689	0.311
V44 Car occupant injured in collision with heavy transport vehicle or bus	0.688	0.312
T82.4 Mechanical complication of vascular dialysis catheter	0.687	0.313
T95 Sequelae of burns, corrosions and frostbite	0.685	0.315
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.685	0.315
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.685	0.315
C23 Malignant neoplasm of gallbladder	0.685	0.315
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.684	0.316
D03 Melanoma in situ	0.684	0.316
X59 Exposure to unspecified factor	0.683	0.317
I21.2 Acute transmural myocardial infarction of other sites	0.683	0.317
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.682	0.318
E23.0 Hypopituitarism	0.682	0.318
I21.0 Acute transmural myocardial infarction of anterior wall	0.682	0.318
C71.3 Parietal lobe	0.682	0.318
E40-E46 Malnutrition	0.681	0.319
I51 Complications and ill-defined descriptions of heart disease	0.680	0.320
I31.8 Other specified diseases of pericardium	0.680	0.320
I31.2 Haemopericardium, not elsewhere classified	0.680	0.320
I31.1 Chronic constrictive pericarditis	0.680	0.320
I31.0 Chronic adhesive pericarditis	0.680	0.320
S20-S29 Injuries to the thorax	0.680	0.320
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.678	0.322
B65-B83 Helminthiases	0.676	0.324
Y84.0 Cardiac catheterisation	0.676	0.324
Y46 Antiepileptics and anti-Parkinsonism drugs	0.674	0.326
S62.31 Fracture of other metacarpal bone (open)	0.673	0.326
I71.8 Aortic aneurysm of unspecified site, ruptured	0.673	0.327
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.673	0.327
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.673	0.327
I71.1 Thoracic aortic aneurysm, ruptured	0.673	0.327
I30 Acute pericarditis	0.673	0.327
B20-B24 Human immunodeficiency virus [HIV] disease	0.672	0.327
C75 Malignant neoplasm of other endocrine glands and related structures	0.672	0.327
C74 Malignant neoplasm of adrenal gland	0.672	0.327
E35 Disorders of endocrine glands in diseases classified elsewhere	0.672	0.328
E32 Diseases of thymus	0.672	0.328
E31 Polyglandular dysfunction	0.672	0.328
E30 Disorders of puberty, not elsewhere classified	0.672	0.328
E25 Adrenogenital disorders	0.672	0.328
Z75.3 Unavailability and inaccessibility of health-care facilities	0.672	0.328
A50-A64 Infections with a predominantly sexual mode of transmission	0.671	0.329
I37 Pulmonary valve disorders	0.670	0.330
Chapter XII Diseases of the skin and subcutaneous tissue	0.670	0.330
T98 Sequelae of other and unspecified effects of external causes	0.669	0.330
I71.0 Dissection of aorta [any part]	0.669	0.331
I34.8 Other nonrheumatic mitral valve disorders	0.669	0.331
I74.9 Embolism and thrombosis of unspecified artery	0.668	0.332
Y53 Agents primarily affecting the gastro-intestinal system	0.666	0.333
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.666	0.334
T93.4 Sequelae of injury of nerve of lower limb	0.666	0.334
X58 Exposure to other specified factors	0.665	0.335
T92.9 Sequelae of unspecified injury of upper limb	0.664	0.336
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.664	0.336
B01 Varicella [chickenpox]	0.663	0.337
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.662	0.338
Z93.9 Artificial opening status, unspecified	0.662	0.338
T15-T19 Effects of foreign body entering through natural orifice	0.660	0.339
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.660	0.340
C38 Malignant neoplasm of heart, mediastinum and pleura	0.660	0.340
C31 Malignant neoplasm of accessory sinuses	0.660	0.340
C37 Malignant neoplasm of thymus	0.660	0.340
C33 Malignant neoplasm of trachea	0.660	0.340
E74 Other disorders of carbohydrate metabolism	0.660	0.340
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites	0.659	0.341
Z76.3 Healthy person accompanying sick person	0.657	0.343
D04 Carcinoma in situ of skin	0.657	0.343
Z99.9 Dependence on unspecified enabling machine and device	0.655	0.345
Z99.4 Dependence on artificial heart	0.655	0.345
Z99.0 Dependence on aspirator	0.655	0.345
L00-L08 Infections of the skin and subcutaneous tissue	0.654	0.346
I21.X Presumed acute myicardial infaction (unconfirmed)	0.654	0.346
C55 Malignant neoplasm of uterus, part unspecified	0.653	0.346
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.653	0.347
L03 Cellulitis	0.653	0.347
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.653	0.347
C57 Malignant neoplasm of other and unspecified female genital organs	0.653	0.347
I45.4 Nonspecific intraventricular block	0.653	0.347
I45.0 Right fascicular block	0.653	0.347
C16.5 Lesser curvature of stomach, unspecified	0.652	0.348
T21 Burn and corrosion of trunk	0.651	0.349
C17.0 Duodenum	0.651	0.349
I22.0 Subsequent myocardial infarction of anterior wall	0.650	0.350
E24 Cushing's syndrome	0.650	0.350
D07 Carcinoma in situ of other and unspecified genital organs	0.649	0.351
E28 Ovarian dysfunction	0.649	0.351
I73.1 Thromboangiitis obliterans [Buerger]	0.649	0.351
T90.5 Sequelae of intracranial injury	0.649	0.351
C16.8 Overlapping lesion of stomach	0.648	0.351
C16.6 Greater curvature of stomach, unspecified	0.648	0.351
C16.4 Pylorus	0.648	0.351
C16.2 Body of stomach	0.648	0.351
C16.1 Fundus of stomach	0.648	0.351
X78 Intentional self-harm by sharp object	0.648	0.352
C18.2 Ascending colon	0.648	0.352
Y04 Assault by bodily force	0.647	0.353
I49 Other cardiac arrhythmias	0.645	0.355
T92.2 Sequelae of fracture at wrist and hand level	0.645	0.355
E78.1 Pure hyperglyceridaemia	0.645	0.355
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.645	0.355
C70 Malignant neoplasm of meninges	0.645	0.355
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.645	0.355
Q80-Q89 Other congenital malformations	0.644	0.356
I21.3 Acute transmural myocardial infarction of unspecified site	0.644	0.356
I34.2 Nonrheumatic mitral (valve) stenosis	0.643	0.356
I45.3 Trifascicular block	0.643	0.357
I36 Nonrheumatic tricuspid valve disorders	0.642	0.358
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.642	0.358
T66-T78 Other and unspecified effects of external causes	0.642	0.358
D05.0 Lobular carcinoma in situ	0.642	0.358
Y49 Psychotropic drugs, not elsewhere classified	0.641	0.359
E27.4 Other and unspecified adrenocortical insufficiency	0.640	0.360
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.640	0.360
I70.1 Atherosclerosis of renal artery	0.640	0.360
V80-V89 Other land transport accidents	0.640	0.360
I78 Diseases of capillaries	0.639	0.361
Q20-Q28 Congenital malformations of the circulatory system	0.637	0.363
Y43 Primarily systemic agents	0.636	0.364
I46.0 Cardiac arrest with successful resuscitation	0.635	0.365
S64 Injury of nerves at wrist and hand level	0.635	0.365
C04 Malignant neoplasm of floor of mouth	0.635	0.365
S67 Crushing injury of wrist and hand	0.633	0.367
I35.1 Aortic (valve) insufficiency	0.632	0.368
V43 Car occupant injured in collision with car, pick-up truck or van	0.631	0.369
S60 Superficial injury of wrist and hand	0.631	0.369
E20 Hypoparathyroidism	0.630	0.369
L03.1 Cellulitis of other parts of limb	0.630	0.370
E34 Other endocrine disorders	0.629	0.371
C34.0 Main bronchus	0.629	0.371
T92.1 Sequelae of fracture of arm	0.629	0.371
B35-B49 Mycoses	0.628	0.372
T11 Other injuries of upper limb, level unspecified	0.628	0.372
S62.0 Fracture of navicular [scaphoid] bone of hand	0.627	0.372
S68 Traumatic amputation of wrist and hand	0.627	0.373
C58 Malignant neoplasm of placenta	0.627	0.373
C52 Malignant neoplasm of vagina	0.627	0.373
Y48 Anaesthetics and therapeutic gases	0.627	0.373
L03.0 Cellulitis of finger and toe	0.626	0.374
C01 Malignant neoplasm of base of tongue	0.626	0.374
T13 Other injuries of lower limb, level unspecified	0.625	0.375
Y47 Sedatives, hypnotics and antianxiety drugs	0.625	0.375
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.624	0.376
T93.0 Sequelae of open wound of lower limb	0.623	0.377
Y65 Other misadventures during surgical and medical care	0.623	0.377
T81.7 Vascular complications following a procedure, not elsewhere classified	0.623	0.377
D02 Carcinoma in situ of middle ear and respiratory system	0.622	0.377
I08 Multiple valve diseases	0.623	0.377
Y84.9 Medical procedure, unspecified	0.622	0.378
Y84.7 Blood-sampling	0.622	0.378
Y84.5 Insertion of gastric or duodenal sound	0.622	0.378
Y84.4 Aspiration of fluid	0.622	0.378
Y84.3 Shock therapy	0.622	0.378
X50 Overexertion and strenuous or repetitive movements	0.622	0.378

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations