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Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77620456
log Bayes Factor = 16.281
Chromosome 1   position 214,788,839  (GRCh37) Explore rs77620456 on Ensembl!
Variant rs77620456 is part of Cluster X0122

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
G40-G47 Episodic and paroxysmal disorders
0.998 0.002 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.998 0.002 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.997 0.003 0.000
Chapter VII Diseases of the eye and adnexa
0.996 0.004 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.996 0.004 0.000
M70-M79 Other soft tissue disorders
0.995 0.005 0.000
Chapter IX Diseases of the circulatory system
0.994 0.006 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.993 0.007 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.993 0.007 0.000
Chapter XX External causes of morbidity and mortality
0.992 0.008 0.000
M20 Acquired deformities of fingers and toes
0.988 0.012 0.000
M23 Internal derangement of knee
0.988 0.012 0.000
R00 Abnormalities of heart beat
0.987 0.013 0.000
H40-H42 Glaucoma
0.980 0.020 0.000
G43 Migraine
0.979 0.021 0.000
G47 Sleep disorders
0.978 0.022 0.000
I10-I15 Hypertensive diseases
0.970 0.030 0.000
H40 Glaucoma
0.969 0.031 0.000
M79.6 Pain in limb
0.966 0.034 0.000
G43.9 Migraine, unspecified
0.965 0.035 0.000
R00.1 Bradycardia, unspecified
0.965 0.035 0.000
H40.9 Glaucoma, unspecified
0.963 0.037 0.000
M79.8 Other specified soft tissue disorders
0.957 0.043 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.956 0.044 0.000
I10 Essential (primary) hypertension
0.954 0.046 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.942 0.058 0.000
R06 Abnormalities of breathing
0.933 0.067 0.000
M20.2 Hallux rigidus
0.931 0.069 0.000
G47.9 Sleep disorder, unspecified
0.924 0.076 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.922 0.078 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.922 0.078 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.916 0.084 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.914 0.086 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.914 0.086 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.911 0.089 0.000
O60-O75 Complications of labour and delivery
0.911 0.089 0.000
S00-S09 Injuries to the head
0.906 0.094 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.905 0.095 0.000
Chapter I Certain infectious and parasitic diseases
0.901 0.099 0.000
G47.3 Sleep apnoea
0.901 0.099 0.000
R47-R49 Symptoms and signs involving speech and voice
0.899 0.101 0.000
M79.66 Pain in limb (Lower leg)
0.899 0.101 0.000
H25-H28 Disorders of lens
0.897 0.103 0.000
M25 Other joint disorders, not elsewhere classified
0.896 0.104 0.000
M20.5 Other deformities of toe(s) (acquired)
0.895 0.105 0.000
G90-G99 Other disorders of the nervous system
0.889 0.111 0.000
I30-I52 Other forms of heart disease
0.889 0.111 0.000
M23.3 Other meniscus derangements
0.886 0.114 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.886 0.114 0.000
T81 Complications of procedures, not elsewhere classified
0.883 0.117 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.880 0.120 0.000
M23.8 Other internal derangements of knee
0.878 0.122 0.000
W00-W19 Falls
0.875 0.125 0.000
I77 Other disorders of arteries and arterioles
0.869 0.131 0.000
R06.5 Mouth breathing
0.868 0.132 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.861 0.139 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.857 0.143 0.000
T66-T78 Other and unspecified effects of external causes
0.856 0.144 0.000
M21 Other acquired deformities of limbs
0.855 0.145 0.000
Chapter X Diseases of the respiratory system
0.854 0.146 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.851 0.149 0.000
O47 False labour
0.849 0.151 0.000
I05-I09 Chronic rheumatic heart diseases
0.848 0.152 0.000
G20-G26 Extrapyramidal and movement disorders
0.846 0.154 0.000
I51 Complications and ill-defined descriptions of heart disease
0.846 0.154 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.845 0.155 0.000
R79 Other abnormal findings of blood chemistry
0.845 0.155 0.000
Chapter VIII Diseases of the ear and mastoid process
0.843 0.157 0.000
H25 Senile cataract
0.842 0.158 0.000
B95-B98 Bacterial, viral and other infectious agents
0.840 0.160 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.840 0.160 0.000
G44 Other headache syndromes
0.838 0.162 0.000
S09 Other and unspecified injuries of head
0.832 0.168 0.000
R02 Gangrene, not elsewhere classified
0.829 0.171 0.000
O80-O84 Delivery
0.826 0.174 0.000
R00.0 Tachycardia, unspecified
0.825 0.175 0.000
R06.0 Dyspnoea
0.823 0.177 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.821 0.179 0.000
M20.0 Deformity of finger(s)
0.816 0.184 0.000
R49 Voice disturbances
0.816 0.184 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.814 0.186 0.000
H53-H54 Visual disturbances and blindness
0.812 0.188 0.000
O42 Premature rupture of membranes
0.811 0.189 0.000
O48 Prolonged pregnancy
0.810 0.190 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.810 0.190 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.808 0.192 0.000
M79.62 Pain in limb (Upper arm)
0.805 0.195 0.000
M79.0 Rheumatism, unspecified
0.805 0.195 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.804 0.196 0.000
G62 Other polyneuropathies
0.803 0.197 0.000
I77.1 Stricture of artery
0.803 0.197 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.802 0.198 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.802 0.198 0.000
E65-E68 Obesity and other hyperalimentation
0.801 0.199 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.800 0.200 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.800 0.200 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.799 0.201 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.797 0.202 0.000
Y86 Sequelae of other accidents
0.797 0.203 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.796 0.204 0.000
R01 Cardiac murmurs and other cardiac sounds
0.795 0.205 0.000
I51.8 Other ill-defined heart diseases
0.795 0.205 0.000
S80-S89 Injuries to the knee and lower leg
0.795 0.205 0.000
S40-S49 Injuries to the shoulder and upper arm
0.795 0.205 0.000
M25.5 Pain in joint
0.791 0.209 0.000
J00-J06 Acute upper respiratory infections
0.790 0.210 0.000
H10-H13 Disorders of conjunctiva
0.790 0.210 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.789 0.211 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.788 0.212 0.000
T87 Complications peculiar to reattachment and amputation
0.787 0.213 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.782 0.218 0.000
M79.7 Fibromyalgia
0.781 0.219 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.781 0.219 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.780 0.220 0.000
S09.9 Unspecified injury of head
0.779 0.221 0.000
M20.4 Other hammer toe(s) (acquired)
0.778 0.222 0.000
H55-H59 Other disorders of eye and adnexa
0.775 0.225 0.000
I60-I69 Cerebrovascular diseases
0.775 0.225 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.774 0.225 0.000
S70-S79 Injuries to the hip and thigh
0.774 0.226 0.000
R30-R39 Symptoms and signs involving the urinary system
0.773 0.227 0.000
R00.2 Palpitations
0.772 0.228 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.771 0.229 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.770 0.230 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.770 0.230 0.000
E10-E14 Diabetes mellitus
0.767 0.233 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.765 0.234 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.765 0.235 0.000
S20-S29 Injuries to the thorax
0.763 0.236 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.762 0.238 0.000
I31 Other diseases of pericardium
0.762 0.238 0.000
M91-M94 Chondropathies
0.762 0.238 0.000
M45-M49 Spondylopathies
0.761 0.239 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.758 0.242 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.758 0.242 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.758 0.242 0.000
R49.0 Dysphonia
0.757 0.243 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.756 0.244 0.000
I49 Other cardiac arrhythmias
0.756 0.244 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.756 0.244 0.000
H40.0 Glaucoma suspect
0.755 0.245 0.000
H25.1 Senile nuclear cataract
0.755 0.245 0.000
R05 Cough
0.754 0.246 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.754 0.246 0.000
T78 Adverse effects, not elsewhere classified
0.753 0.247 0.000
H65-H75 Diseases of middle ear and mastoid
0.752 0.248 0.000
W19 Unspecified fall
0.751 0.249 0.000
M80-M85 Disorders of bone density and structure
0.751 0.249 0.000
R31 Unspecified haematuria
0.751 0.249 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.750 0.249 0.000
Chapter XXII Codes for special purposes
0.750 0.250 0.000
T86 Failure and rejection of transplanted organs and tissues
0.750 0.250 0.000
S10-S19 Injuries to the neck
0.749 0.251 0.000
M23.4 Loose body in knee
0.747 0.253 0.000
R04 Haemorrhage from respiratory passages
0.745 0.255 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.745 0.255 0.000
E66 Obesity
0.744 0.256 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.742 0.258 0.000
Chapter II Neoplasms
0.741 0.259 0.000
M65-M68 Disorders of synovium and tendon
0.741 0.259 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.741 0.259 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.740 0.260 0.000
Y88 Sequelae of surgical and medical care as external cause
0.740 0.260 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.740 0.260 0.000
I95 Hypotension
0.739 0.261 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.739 0.261 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.736 0.264 0.000
H25.9 Senile cataract, unspecified
0.736 0.264 0.000
S90-S99 Injuries to the ankle and foot
0.736 0.264 0.000
I51.7 Cardiomegaly
0.735 0.265 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.734 0.266 0.000
G95 Other diseases of spinal cord
0.734 0.266 0.000
M79.63 Pain in limb (Forearm)
0.734 0.266 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.733 0.267 0.000
G61 Inflammatory polyneuropathy
0.733 0.267 0.000
M22 Disorders of patella
0.732 0.267 0.000
G93 Other disorders of brain
0.731 0.269 0.000
T79-T79 Certain early complications of trauma
0.730 0.270 0.000
G25 Other extrapyramidal and movement disorders
0.730 0.270 0.000
M20.1 Hallux valgus (acquired)
0.729 0.271 0.000
Y85 Sequelae of transport accidents
0.729 0.271 0.000
M86-M90 Other osteopathies
0.729 0.271 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.729 0.271 0.000
Y84.8 Other medical procedures
0.728 0.272 0.000
M79.64 Pain in limb (Hand)
0.727 0.273 0.000
H54 Blindness and low vision
0.727 0.273 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.726 0.274 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.724 0.276 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.724 0.276 0.000
G62.9 Polyneuropathy, unspecified
0.724 0.276 0.000
G44.2 Tension-type headache
0.723 0.277 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.722 0.277 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.722 0.278 0.000
M79.69 Pain in limb (Site unspecified)
0.719 0.281 0.000
O00-O08 Pregnancy with abortive outcome
0.718 0.282 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.718 0.282 0.000
R73 Elevated blood glucose level
0.717 0.282 0.000
M21.3 Wrist or foot drop (acquired)
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
M34 Systemic sclerosis
0.717 0.283 0.000
M33 Dermatopolymyositis
0.717 0.283 0.000
M32 Systemic lupus erythematosus
0.717 0.283 0.000
M30 Polyarteritis nodosa and related conditions
0.717 0.283 0.000
G70-G73 Diseases of myoneural junction and muscle
0.717 0.283 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
H27 Other disorders of lens
0.716 0.283 0.000
I47 Paroxysmal tachycardia
0.716 0.284 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.716 0.284 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.716 0.284 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.716 0.284 0.000
G41 Status epilepticus
0.716 0.284 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.715 0.284 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.714 0.285 0.000
T85.2 Mechanical complication of intraocular lens
0.714 0.286 0.000
E66.9 Obesity, unspecified
0.714 0.286 0.000
M76 Enthesopathies of lower limb, excluding foot
0.713 0.286 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.713 0.286 0.000
M71 Other bursopathies
0.713 0.286 0.000
Y83.4 Other reconstructive surgery
0.714 0.286 0.000
I00-I02 Acute rheumatic fever
0.713 0.287 0.000
M79.9 Soft tissue disorder, unspecified
0.712 0.288 0.000
M79.5 Residual foreign body in soft tissue
0.712 0.288 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.712 0.288 0.000
M79.3 Panniculitis, unspecified
0.712 0.288 0.000
M79.2 Neuralgia and neuritis, unspecified
0.712 0.288 0.000
M79.1 Myalgia
0.712 0.288 0.000
O85-O92 Complications predominantly related to the puerperium
0.712 0.288 0.000
G43.1 Migraine with aura [classical migraine]
0.712 0.288 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.712 0.288 0.000
M79.60 Pain in limb (Multiple sites)
0.712 0.288 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.711 0.289 0.000
Y35-Y36 Legal intervention and operations of war
0.711 0.289 0.000
Y10-Y34 Event of undetermined intent
0.711 0.289 0.000
Y00-Y09 Assault
0.711 0.289 0.000
X85-X99 Assault
0.711 0.289 0.000
X60-X84 Intentional self-harm
0.711 0.289 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.711 0.289 0.000
X50-X57 Overexertion, travel and privation
0.711 0.289 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.711 0.289 0.000
X30-X39 Exposure to forces of nature
0.711 0.289 0.000
X20-X29 Contact with venomous animals and plants
0.711 0.289 0.000
X10-X19 Contact with heat and hot substances
0.711 0.289 0.000
X00-X09 Exposure to smoke, fire and flames
0.711 0.289 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.711 0.289 0.000
W75-W84 Other accidental threats to breathing
0.711 0.289 0.000
W65-W74 Accidental drowning and submersion
0.711 0.289 0.000
W50-W64 Exposure to animate mechanical forces
0.711 0.289 0.000
W20-W49 Exposure to inanimate mechanical forces
0.711 0.289 0.000
V98-V99 Other and unspecified transport accidents
0.711 0.289 0.000
V95-V97 Air and space transport accidents
0.711 0.289 0.000
V90-V94 Water transport accidents
0.711 0.289 0.000
V80-V89 Other land transport accidents
0.711 0.289 0.000
V70-V79 Bus occupant injured in transport accident
0.711 0.289 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.711 0.289 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.711 0.289 0.000
V40-V49 Car occupant injured in transport accident
0.711 0.289 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.711 0.289 0.000
V20-V29 Motorcycle rider injured in transport accident
0.711 0.289 0.000
V01-V09 Pedestrian injured in transport accident
0.711 0.289 0.000
O30 Multiple gestation
0.711 0.289 0.000
J03 Acute tonsillitis
0.710 0.290 0.000
S00 Superficial injury of head
0.709 0.291 0.000
I08 Multiple valve diseases
0.709 0.291 0.000
M20.3 Other deformity of hallux (acquired)
0.708 0.291 0.000
M23.9 Internal derangement of knee, unspecified
0.708 0.292 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.708 0.292 0.000
M23.5 Chronic instability of knee
0.708 0.292 0.000
M23.1 Discoid meniscus (congenital)
0.708 0.292 0.000
M23.0 Cystic meniscus
0.708 0.292 0.000
V10-V19 Pedal cyclist injured in transport accident
0.707 0.293 0.000
M79.67 Pain in limb (Ankle and foot)
0.706 0.294 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.705 0.295 0.000
R79.0 Abnormal level of blood mineral
0.704 0.296 0.000
Chapter XXI Factors influencing health status and contact with health services
0.703 0.297 0.000
H42 Glaucoma in diseases classified elsewhere
0.703 0.297 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.703 0.297 0.000
G43.8 Other migraine
0.702 0.298 0.000
G43.3 Complicated migraine
0.702 0.298 0.000
G43.2 Status migrainosus
0.702 0.298 0.000
G43.0 Migraine without aura [common migraine]
0.702 0.298 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.702 0.298 0.000
O72 Postpartum haemorrhage
0.702 0.298 0.000
M31 Other necrotising vasculopathies
0.701 0.299 0.000
G47.8 Other sleep disorders
0.701 0.299 0.000
G47.4 Narcolepsy and cataplexy
0.701 0.299 0.000
G47.2 Disorders of the sleep-wake schedule
0.701 0.299 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.701 0.299 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.701 0.299 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.700 0.300 0.000
M25.51 Pain in joint (Shoulder region)
0.700 0.300 0.000
B15-B19 Viral hepatitis
0.700 0.300 0.000
R76 Other abnormal immunological findings in serum
0.699 0.301 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.698 0.302 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.697 0.302 0.000
M75 Shoulder lesions
0.697 0.303 0.000
I15 Secondary hypertension
0.696 0.304 0.000
I13 Hypertensive heart and renal disease
0.696 0.304 0.000
I11 Hypertensive heart disease
0.696 0.304 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.696 0.304 0.000
M77 Other enthesopathies
0.696 0.304 0.000
M40-M43 Deforming dorsopathies
0.695 0.305 0.000
O63 Long labour
0.695 0.305 0.000
H40.8 Other glaucoma
0.694 0.305 0.000
H40.6 Glaucoma secondary to drugs
0.694 0.305 0.000
H40.5 Glaucoma secondary to other eye disorders
0.694 0.305 0.000
H40.4 Glaucoma secondary to eye inflammation
0.694 0.305 0.000
H40.3 Glaucoma secondary to eye trauma
0.694 0.305 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.694 0.306 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.693 0.307 0.000
S82 Fracture of lower leg, including ankle
0.693 0.307 0.000
G40 Epilepsy
0.693 0.307 0.000
M79.68 Pain in limb (Other)
0.692 0.307 0.000
M79.61 Pain in limb (Shoulder region)
0.692 0.307 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.692 0.308 0.000
A30-A49 Other bacterial diseases
0.691 0.309 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.691 0.309 0.000
W06 Fall involving bed
0.691 0.309 0.000
I12 Hypertensive renal disease
0.690 0.310 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.690 0.310 0.000
O47.9 False labour, unspecified
0.690 0.310 0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)
0.690 0.310 0.000
I74 Arterial embolism and thrombosis
0.689 0.311 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.687 0.313 0.000
M79.88 Other specified soft tissue disorders (Other)
0.686 0.313 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.686 0.313 0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.686 0.313 0.000
M79.83 Other specified soft tissue disorders (Forearm)
0.686 0.313 0.000
M79.82 Other specified soft tissue disorders (Upper arm)
0.686 0.313 0.000
M79.81 Other specified soft tissue disorders (Shoulder region)
0.686 0.313 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.686 0.313 0.000
O45 Premature separation of placenta [abruptio placentae]
0.685 0.315 0.000
O44 Placenta praevia
0.685 0.315 0.000
O43 Placental disorders
0.685 0.315 0.000
O41 Other disorders of amniotic fluid and membranes
0.685 0.315 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.685 0.315 0.000
O33 Maternal care for known or suspected disproportion
0.685 0.315 0.000
O31 Complications specific to multiple gestation
0.685 0.315 0.000
O40 Polyhydramnios
0.685 0.315 0.000
B25-B34 Other viral diseases
0.685 0.315 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.685 0.315 0.000
B35-B49 Mycoses
0.684 0.315 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.684 0.316 0.000
R47 Speech disturbances, not elsewhere classified
0.683 0.317 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.683 0.317 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.682 0.318 0.000
M24 Other specific joint derangements
0.681 0.318 0.000
E40-E46 Malnutrition
0.681 0.319 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.676 0.324 0.000
T80.2 Infections following infusion, transfusion and therapeutic injection
0.676 0.324 0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.675 0.324 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.675 0.324 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.675 0.324 0.000
T83.2 Mechanical complication of graft of urinary organ
0.675 0.324 0.000
M21.1 Varus deformity, not elsewhere classified
0.674 0.326 0.000
M25.7 Osteophyte
0.674 0.326 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.674 0.326 0.000
M35 Other systemic involvement of connective tissue
0.673 0.326 0.000
R06.4 Hyperventilation
0.673 0.327 0.000
G24 Dystonia
0.673 0.327 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.671 0.329 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.671 0.329 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.670 0.330 0.000
G51 Facial nerve disorders
0.670 0.330 0.000
H40.2 Primary angle-closure glaucoma
0.669 0.331 0.000
R06.7 Sneezing
0.669 0.331 0.000
R06.6 Hiccough
0.669 0.331 0.000
R06.3 Periodic breathing
0.669 0.331 0.000
R06.2 Wheezing
0.669 0.331 0.000
R06.1 Stridor
0.669 0.331 0.000
C43 Malignant melanoma of skin
0.668 0.332 0.000
I30 Acute pericarditis
0.667 0.333 0.000
H18 Other disorders of cornea
0.666 0.334 0.000
H71 Cholesteatoma of middle ear
0.666 0.334 0.000
G30-G32 Other degenerative diseases of the nervous system
0.664 0.335 0.000
T92 Sequelae of injuries of upper limb
0.664 0.336 0.000
I31.9 Disease of pericardium, unspecified
0.663 0.337 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.663 0.337 0.000
Chapter V Mental and behavioural disorders
0.663 0.337 0.000
O75.7 Vaginal delivery following previous Caesarean section
0.662 0.338 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.661 0.339 0.000
R77 Other abnormalities of plasma proteins
0.661 0.339 0.000
R74 Abnormal serum enzyme levels
0.661 0.339 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.661 0.339 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.661 0.339 0.000
R71 Abnormality of red blood cells
0.661 0.339 0.000
I62 Other nontraumatic intracranial haemorrhage
0.660 0.340 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.659 0.341 0.000
R04.0 Epistaxis
0.659 0.341 0.000
W19.9 Unspecified place
0.658 0.342 0.000
Y83.9 Surgical procedure, unspecified
0.657 0.343 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.657 0.343 0.000
O36 Maternal care for other known or suspected foetal problems
0.657 0.343 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.656 0.344 0.000
S06 Intracranial injury
0.656 0.344 0.000
G60 Hereditary and idiopathic neuropathy
0.656 0.344 0.000
G64 Other disorders of peripheral nervous system
0.656 0.344 0.000
Y89 Sequelae of other external causes
0.655 0.345 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.655 0.345 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.655 0.345 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.653 0.346 0.000
I72 Other aneurysm
0.653 0.346 0.000
O81 Single delivery by forceps and vacuum extractor
0.653 0.346 0.000
O74 Complications of anaesthesia during labour and delivery
0.653 0.347 0.000
O73 Retained placenta and membranes, without haemorrhage
0.653 0.347 0.000
O71 Other obstetric trauma
0.653 0.347 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.653 0.347 0.000
O66 Other obstructed labour
0.653 0.347 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.653 0.347 0.000
O62 Abnormalities of forces of labour
0.653 0.347 0.000
O61 Failed induction of labour
0.653 0.347 0.000
O60 Preterm delivery
0.653 0.347 0.000
J03.9 Acute tonsillitis, unspecified
0.653 0.347 0.000
O42.9 Premature rupture of membranes, unspecified
0.653 0.347 0.000
H54.4 Blindness, one eye
0.652 0.348 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.652 0.348 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.652 0.348 0.000
W13 Fall from, out of or through building or structure
0.651 0.349 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.651 0.349 0.000
M25.57 Pain in joint (Ankle and foot)
0.651 0.349 0.000
O70 Perineal laceration during delivery
0.650 0.350 0.000
S08 Traumatic amputation of part of head
0.649 0.350 0.000
S07 Crushing injury of head
0.649 0.350 0.000
S05 Injury of eye and orbit
0.649 0.350 0.000
S04 Injury of cranial nerves
0.649 0.350 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.649 0.350 0.000
E10 Insulin-dependent diabetes mellitus
0.649 0.351 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.649 0.351 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.649 0.351 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.649 0.351 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.648 0.352 0.000
H60-H62 Diseases of external ear
0.648 0.352 0.000
B99-B99 Other infectious diseases
0.646 0.354 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.646 0.354 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.646 0.354 0.000
B65-B83 Helminthiases
0.646 0.354 0.000
B50-B64 Protozoal diseases
0.646 0.354 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.646 0.354 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.646 0.354 0.000
A80-A89 Viral infections of the central nervous system
0.646 0.354 0.000
A75-A79 Rickettsioses
0.646 0.354 0.000
A70-A74 Other diseases caused by chlamydiae
0.646 0.354 0.000
A65-A69 Other spirochaetal diseases
0.646 0.354 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.646 0.354 0.000
A20-A28 Certain zoonotic bacterial diseases
0.646 0.354 0.000
A15-A19 Tuberculosis
0.646 0.354 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.646 0.354 0.000
R33 Retention of urine
0.646 0.354 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.645 0.355 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.645 0.355 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.645 0.355 0.000
I07 Rheumatic tricuspid valve diseases
0.644 0.356 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.643 0.356 0.000
M25.9 Joint disorder, unspecified
0.642 0.358 0.000
M25.8 Other specified joint disorders
0.642 0.358 0.000
M25.3 Other instability of joint
0.642 0.358 0.000
M25.2 Flail joint
0.642 0.358 0.000
M25.1 Fistula of joint
0.642 0.358 0.000
M25.0 Haemarthrosis
0.642 0.358 0.000
H11 Other disorders of conjunctiva
0.642 0.358 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.641 0.359 0.000
H25.0 Senile incipient cataract
0.641 0.359 0.000
I34 Nonrheumatic mitral valve disorders
0.641 0.359 0.000
R80 Isolated proteinuria
0.640 0.360 0.000
D10-D36 Benign neoplasms
0.640 0.360 0.000
S00.9 Superficial injury of head, part unspecified
0.639 0.361 0.000
I70 Atherosclerosis
0.639 0.361 0.000
M72 Fibroblastic disorders
0.638 0.361 0.000
C44 Other malignant neoplasms of skin
0.638 0.362 0.000
J30-J39 Other diseases of upper respiratory tract
0.638 0.362 0.000
O16 Unspecified maternal hypertension
0.638 0.362 0.000
I49.8 Other specified cardiac arrhythmias
0.638 0.362 0.000
T87.6 Other and unspecified complications of amputation stump
0.637 0.362 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.637 0.363 0.000
G96 Other disorders of central nervous system
0.637 0.363 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.637 0.363 0.000
G90 Disorders of autonomic nervous system
0.637 0.363 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.637 0.363 0.000
G92 Toxic encephalopathy
0.637 0.363 0.000
I52 Other heart disorders in diseases classified elsewhere
0.637 0.363 0.000
I48 Atrial fibrillation and flutter
0.637 0.363 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.637 0.363 0.000
I41 Myocarditis in diseases classified elsewhere
0.637 0.363 0.000
I40 Acute myocarditis
0.637 0.363 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.637 0.363 0.000
I37 Pulmonary valve disorders
0.637 0.363 0.000
I36 Nonrheumatic tricuspid valve disorders
0.637 0.363 0.000
I33 Acute and subacute endocarditis
0.637 0.363 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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