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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3129904
log Bayes Factor = 212.446
Chromosome 6   position 32,310,396  (GRCh37) Explore rs3129904 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
J33 Nasal polyp
0.000 0.000 1.000
E14.9 Without complications
0.000 0.000 1.000
J33.0 Polyp of nasal cavity
0.000 0.000 1.000
E10.4 With neurological complications
0.000 0.000 1.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
J33.9 Nasal polyp, unspecified
0.000 0.001 0.999
M35.3 Polymyalgia rheumatica
0.000 0.001 0.999
E70-E90 Metabolic disorders
0.000 0.001 0.999
E11.3 With ophthalmic complications
0.000 0.002 0.998
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.002 0.998
E05.9 Thyrotoxicosis, unspecified
0.000 0.002 0.998
M07 Psoriatic and enteropathic arthropathies
0.000 0.002 0.998
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.002 0.998
L40-L45 Papulosquamous disorders
0.000 0.002 0.998
M07.3 Other psoriatic arthropathies
0.000 0.003 0.997
H36 Retinal disorders in diseases classified elsewhere
0.000 0.004 0.996
E14.3 With ophthalmic complications
0.000 0.004 0.996
L40.9 Psoriasis, unspecified
0.000 0.005 0.995
H30-H36 Disorders of choroid and retina
0.000 0.006 0.994
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.007 0.993
E10.5 With peripheral circulatory complications
0.000 0.008 0.992
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.008 0.992
J33.8 Other polyp of sinus
0.000 0.009 0.991
M35 Other systemic involvement of connective tissue
0.000 0.009 0.991
E11.1 With ketoacidosis
0.000 0.009 0.991
G35-G37 Demyelinating diseases of the central nervous system
0.986 0.013 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.015 0.985
G37 Other demyelinating diseases of central nervous system
0.983 0.016 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.017 0.983
M20-M25 Other joint disorders
0.000 0.018 0.982
L43 Lichen planus
0.000 0.019 0.981
G37.9 Demyelinating disease of central nervous system, unspecified
0.979 0.021 0.000
# Top node
0.000 0.023 0.977
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.023 0.977
E10.2 With renal complications
0.000 0.026 0.974
Chapter VII Diseases of the eye and adnexa
0.000 0.027 0.973
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.031 0.969
E06 Thyroiditis
0.000 0.033 0.967
I10 Essential (primary) hypertension
0.000 0.035 0.965
I10-I15 Hypertensive diseases
0.000 0.037 0.963
H34 Retinal vascular occlusions
0.000 0.042 0.958
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.043 0.957
L43.9 Lichen planus, unspecified
0.000 0.045 0.955
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.046 0.954
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.047 0.953
E10.8 With unspecified complications
0.000 0.047 0.953
E06.3 Autoimmune thyroiditis
0.000 0.053 0.947
Chapter IX Diseases of the circulatory system
0.000 0.055 0.945
M45-M49 Spondylopathies
0.000 0.056 0.944
M45 Ankylosing spondylitis
0.000 0.057 0.943
M65-M68 Disorders of synovium and tendon
0.000 0.058 0.942
E10.0 With coma
0.000 0.059 0.941
M06.0 Seronegative rheumatoid arthritis
0.000 0.060 0.940
M34 Systemic sclerosis
0.000 0.062 0.938
M06.3 Rheumatoid nodule
0.000 0.063 0.937
H35 Other retinal disorders
0.000 0.072 0.928
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.073 0.927
I12 Hypertensive renal disease
0.000 0.074 0.926
H40-H42 Glaucoma
0.000 0.075 0.925
M65 Synovitis and tenosynovitis
0.000 0.076 0.924
M06.4 Inflammatory polyarthropathy
0.000 0.081 0.919
I22 Subsequent myocardial infarction
0.000 0.091 0.909
I12.9 Hypertensive renal disease without renal failure
0.000 0.092 0.908
I20-I25 Ischaemic heart diseases
0.000 0.093 0.907
E07 Other disorders of thyroid
0.000 0.094 0.906
E11.5 With peripheral circulatory complications
0.000 0.094 0.906
E78.2 Mixed hyperlipidaemia
0.000 0.102 0.898
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.104 0.896
M65.9 Synovitis and tenosynovitis, unspecified
0.000 0.105 0.895
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.105 0.895
H35.8 Other specified retinal disorders
0.000 0.106 0.894
H40 Glaucoma
0.000 0.108 0.892
E78.1 Pure hyperglyceridaemia
0.000 0.109 0.891
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.110 0.890
H40.9 Glaucoma, unspecified
0.000 0.110 0.890
E11.2 With renal complications
0.000 0.112 0.888
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.116 0.884
H35.4 Peripheral retinal degeneration
0.000 0.120 0.880
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.122 0.878
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.125 0.875
E88 Other metabolic disorders
0.000 0.125 0.875
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.127 0.873
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.129 0.871
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.138 0.862
H34.2 Other retinal artery occlusions
0.000 0.138 0.862
H34.8 Other retinal vascular occlusions
0.000 0.139 0.861
M34.1 CR(E)ST syndrome
0.000 0.147 0.853
L40.8 Other psoriasis
0.000 0.147 0.853
G37.8 Other specified demyelinating diseases of central nervous system
0.851 0.149 0.000
L43.8 Other lichen planus
0.000 0.150 0.850
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.150 0.850
M35.1 Other overlap syndromes
0.000 0.151 0.849
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.154 0.846
M35.7 Hypermobility syndrome
0.000 0.160 0.840
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.164 0.836
M34.9 Systemic sclerosis, unspecified
0.000 0.166 0.834
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.167 0.833
M06.34 Rheumatoid nodule (Hand)
0.000 0.172 0.828
L57.0 Actinic keratosis
0.000 0.179 0.821
E07.9 Disorder of thyroid, unspecified
0.000 0.180 0.820
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.181 0.819
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.183 0.817
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.184 0.816
E10.6 With other specified complications
0.000 0.185 0.815
E74 Other disorders of carbohydrate metabolism
0.000 0.186 0.814
E78.6 Lipoprotein deficiency
0.000 0.187 0.813
E89.0 Postprocedural hypothyroidism
0.000 0.190 0.810
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.192 0.808
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.000 0.195 0.805
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.199 0.801
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.201 0.799
E11.8 With unspecified complications
0.000 0.205 0.795
H35.6 Retinal haemorrhage
0.000 0.206 0.794
E14.4 With neurological complications
0.000 0.211 0.789
L40.1 Generalised pustular psoriasis
0.000 0.215 0.785
E03.8 Other specified hypothyroidism
0.000 0.215 0.785
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)
0.000 0.218 0.782
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.221 0.779
H43-H45 Disorders of vitreous body and globe
0.000 0.222 0.778
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.000 0.223 0.777
M31 Other necrotising vasculopathies
0.000 0.223 0.777
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.000 0.225 0.775
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.227 0.773
M30 Polyarteritis nodosa and related conditions
0.000 0.230 0.770
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.242 0.758
M35.2 Behcet's disease
0.000 0.242 0.758
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.248 0.752
E14.5 With peripheral circulatory complications
0.000 0.248 0.752
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.251 0.749
M65.1 Other infective (teno)synovitis
0.000 0.252 0.748
H35.7 Separation of retinal layers
0.000 0.254 0.746
E83 Disorders of mineral metabolism
0.333 0.263 0.404
L40.3 Pustulosis palmaris et plantaris
0.000 0.269 0.731
E14.2 Withrenal complications
0.000 0.270 0.730
I22.8 Subsequent myocardial infarction of other sites
0.000 0.270 0.730
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.273 0.727
H34.1 Central retinal artery occlusion
0.000 0.273 0.727
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.274 0.726
G36 Other acute disseminated demyelination
0.723 0.277 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.278 0.722
M14 Arthropathies in other diseases classified elsewhere
0.000 0.281 0.719
H34.9 Retinal vascular occlusion, unspecified
0.000 0.282 0.718
H43 Disorders of vitreous body
0.000 0.283 0.717
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E14.8 With unspecified complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.6 With other specified complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.2 Rheumatoid vasculitis
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
J33.1 Polypoid sinus degeneration
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
E78.3 Hyperchylomicronaemia
0.000 0.283 0.717
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E77 Disorders of glycoprotein metabolism
0.000 0.283 0.716
E76 Disorders of glycosaminoglycan metabolism
0.000 0.283 0.716
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.283 0.716
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.283 0.716
H40.4 Glaucoma secondary to eye inflammation
0.000 0.284 0.716
H30 Chorioretinal inflammation
0.000 0.284 0.716
M07.5 Arthropathy in ulcerative colitis
0.000 0.284 0.715
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.284 0.715
M07.2 Psoriatic spondylitis
0.000 0.284 0.715
M07.1 Arthritis mutilans
0.000 0.284 0.715
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.284 0.715
L44 Other papulosquamous disorders
0.000 0.285 0.715
L41 Parapsoriasis
0.000 0.285 0.715
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.285 0.715
M07.38 Other psoriatic arthropathies (Other)
0.000 0.285 0.715
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.285 0.715
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.285 0.715
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.285 0.715
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.285 0.715
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.285 0.715
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.285 0.714
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.286 0.714
I11 Hypertensive heart disease
0.000 0.286 0.714
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.000 0.287 0.713
L40.0 Psoriasis vulgaris
0.000 0.287 0.713
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.287 0.713
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.289 0.711
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.289 0.711
M35.5 Multifocal fibrosclerosis
0.000 0.289 0.711
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.289 0.711
E07.8 Other specified disorders of thyroid
0.000 0.292 0.708
E40-E46 Malnutrition
0.000 0.293 0.706
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.294 0.706
G37.5 Concentric sclerosis [Balo]
0.705 0.295 0.000
G37.4 Subacute necrotising myelitis
0.705 0.295 0.000
G37.2 Central pontine myelinolysis
0.705 0.295 0.000
G37.1 Central demyelination of corpus callosum
0.705 0.295 0.000
G37.0 Diffuse sclerosis
0.705 0.295 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.296 0.704
L43.3 Subacute (active) lichen planus
0.000 0.297 0.703
L43.2 Lichenoid drug reaction
0.000 0.297 0.703
L43.1 Bullous lichen planus
0.000 0.297 0.703
L43.0 Hypertrophic lichen planus
0.000 0.297 0.703
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)
0.000 0.297 0.703
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.297 0.703
I15 Secondary hypertension
0.000 0.299 0.701
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.299 0.700
E70 Disorders of aromatic amino-acid metabolism
0.000 0.300 0.700
E88.8 Other specified metabolic disorders
0.000 0.304 0.696
E88.2 Lipomatosis, not elsewhere classified
0.000 0.304 0.696
E06.5 Other chronic thyroiditis
0.000 0.307 0.693
E06.4 Drug-induced thyroiditis
0.000 0.307 0.693
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.307 0.693
E06.1 Subacute thyroiditis
0.000 0.307 0.693
E06.0 Acute thyroiditis
0.000 0.307 0.693
E79 Disorders of purine and pyrimidine metabolism
0.000 0.308 0.691
I13 Hypertensive heart and renal disease
0.000 0.309 0.690
E11.6 With other specified complications
0.000 0.310 0.690
E13 Other specified diabetes mellitus
0.000 0.310 0.690
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.312 0.688
H34.0 Transient retinal artery occlusion
0.000 0.313 0.687
I00-I02 Acute rheumatic fever
0.000 0.314 0.686
M34.8 Other forms of systemic sclerosis
0.000 0.314 0.685
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.316 0.684
M49 Spondylopathies in diseases classified elsewhere
0.000 0.318 0.682
M66 Spontaneous rupture of synovium and tendon
0.000 0.318 0.682
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.319 0.681
M12 Other specific arthropathies
0.000 0.321 0.679
H35.2 Other proliferative retinopathy
0.000 0.323 0.677
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.324 0.676
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.324 0.676
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.324 0.676
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.324 0.676
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.324 0.676
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.324 0.676
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.324 0.676
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.326 0.674
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.326 0.674
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.326 0.674
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.326 0.674
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.326 0.674
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.326 0.674
M34.2 Systemic sclerosis induced by drugs and chemicals
0.000 0.327 0.673
M34.0 Progressive systemic sclerosis
0.000 0.327 0.673
E78.4 Other hyperlipidaemia
0.000 0.328 0.672
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.328 0.672
M06.38 Rheumatoid nodule (Other)
0.000 0.328 0.672
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.328 0.672
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.328 0.672
M06.33 Rheumatoid nodule (Forearm)
0.000 0.328 0.672
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.328 0.672
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.328 0.672
M07.6 Other enteropathic arthropathies
0.000 0.332 0.668
E84 Cystic fibrosis
0.000 0.334 0.666
E16.1 Other hypoglycaemia
0.000 0.334 0.665
H35.1 Retinopathy of prematurity
0.000 0.335 0.665
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.335 0.665
H42 Glaucoma in diseases classified elsewhere
0.000 0.336 0.663
M65.2 Calcific tendinitis
0.000 0.337 0.663
M65.0 Abscess of tendon sheath
0.000 0.337 0.663
M86-M90 Other osteopathies
0.000 0.339 0.660
E72 Other disorders of amino-acid metabolism
0.000 0.341 0.659
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.341 0.659
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.341 0.659
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.341 0.659
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.341 0.659
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.341 0.659
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.341 0.659
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.341 0.659
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.341 0.659
M91-M94 Chondropathies
0.000 0.341 0.659
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.343 0.657
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.344 0.655
M80-M85 Disorders of bone density and structure
0.000 0.349 0.651
H40.5 Glaucoma secondary to other eye disorders
0.000 0.349 0.651
E07.1 Dyshormogenetic goitre
0.000 0.350 0.650
E07.0 Hypersecretion of calcitonin
0.000 0.350 0.650
M31.6 Other giant cell arteritis
0.000 0.351 0.649
E89.4 Postprocedural ovarian failure
0.000 0.354 0.646
M65.98 Synovitis and tenosynovitis, unspecified (Other)
0.000 0.358 0.642
E06.9 Thyroiditis, unspecified
0.000 0.358 0.642
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.359 0.641
L10-L14 Bullous disorders
0.000 0.360 0.640
H40.6 Glaucoma secondary to drugs
0.000 0.361 0.639
H40.3 Glaucoma secondary to eye trauma
0.000 0.361 0.639
L55 Sunburn
0.000 0.361 0.638
M32 Systemic lupus erythematosus
0.000 0.361 0.638
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)
0.000 0.362 0.638
M11 Other crystal arthropathies
0.000 0.367 0.633
H40.1 Primary open-angle glaucoma
0.000 0.367 0.633
H43.3 Other vitreous opacities
0.000 0.370 0.630
E88.3 Tumour lysis syndrome
0.000 0.370 0.630
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.371 0.629
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec
0.000 0.372 0.627
M65.48 Radial styloid tenosynovitis [de Quervain]-Other
0.000 0.372 0.627
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot
0.000 0.372 0.627
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg
0.000 0.372 0.627
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh
0.000 0.372 0.627
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm
0.000 0.372 0.627
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region
0.000 0.372 0.627
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)
0.000 0.372 0.627
E88.9 Metabolic disorder, unspecified
0.000 0.373 0.627
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.373 0.627
E11.4 With neurological complications
0.000 0.373 0.627
L80 Vitiligo
0.000 0.377 0.623
E65-E68 Obesity and other hyperalimentation
0.000 0.377 0.623
M65.14 Other infective (teno)synovitis (Hand)
0.000 0.378 0.622
Chapter VIII Diseases of the ear and mastoid process
0.000 0.379 0.621
L20-L30 Dermatitis and eczema
0.000 0.379 0.621
H33 Retinal detachments and breaks
0.000 0.380 0.620
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.382 0.618
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.382 0.618
E89.5 Postprocedural testicular hypofunction
0.000 0.382 0.618
E89.1 Postprocedural hypoinsulinaemia
0.000 0.382 0.618
D64.9 Anaemia, unspecified
0.000 0.383 0.617
L42 Pityriasis rosea
0.000 0.386 0.613
M86 Osteomyelitis
0.000 0.388 0.612
H43.9 Disorder of vitreous body, unspecified
0.000 0.390 0.610
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.391 0.609
E89.3 Postprocedural hypopituitarism
0.000 0.392 0.608
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.392 0.607
E05.8 Other thyrotoxicosis
0.000 0.393 0.607
L57.5 Actinic granuloma
0.000 0.393 0.607
L57.3 Poikiloderma of Civatte
0.000 0.393 0.607
L57.2 Cutis rhomboidalis nuchae
0.000 0.393 0.607
L57.1 Actinic reticuloid
0.000 0.393 0.607
E80.4 Gilbert's syndrome
0.000 0.395 0.605
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.395 0.605
D64 Other anaemias
0.000 0.396 0.604
D60-D64 Aplastic and other anaemias
0.000 0.399 0.601
M31.9 Necrotising vasculopathy, unspecified
0.000 0.401 0.599
L28 Lichen simplex chronicus and prurigo
0.000 0.402 0.598
E73 Lactose intolerance
0.000 0.403 0.597
M31.3 Wegener's granulomatosis
0.000 0.403 0.597
M60-M63 Disorders of muscles
0.000 0.405 0.595
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.000 0.408 0.591
M82 Osteoporosis in diseases classified elsewhere
0.000 0.409 0.591
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.410 0.590
M86.9 Osteomyelitis, unspecified
0.000 0.413 0.586
M80 Osteoporosis with pathological fracture
0.000 0.413 0.587
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.413 0.586
H60-H62 Diseases of external ear
0.000 0.414 0.586
M33 Dermatopolymyositis
0.000 0.415 0.585
M30.0 Polyarteritis nodosa
0.000 0.416 0.584
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.416 0.584
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.416 0.584
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.416 0.584
E74.2 Disorders of galactose metabolism
0.000 0.416 0.584
E74.1 Disorders of fructose metabolism
0.000 0.416 0.584
E74.0 Glycogen storage disease
0.000 0.416 0.584
L58 Radiodermatitis
0.000 0.417 0.582
E11.0 With coma
0.000 0.420 0.579
M14.6 Neuropathic arthropathy
0.000 0.423 0.577
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.000 0.425 0.575
L28.0 Lichen simplex chronicus
0.000 0.427 0.573
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.432 0.568
I21 Acute myocardial infarction
0.000 0.433 0.567
M31.1 Thrombotic microangiopathy
0.000 0.436 0.564
L85 Other epidermal thickening
0.000 0.437 0.563
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.438 0.562
M80.9 Unspecified osteoporosis with pathological fracture
0.000 0.439 0.561
E03.1 Congenital hypothyroidism without goitre
0.000 0.439 0.560
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.000 0.440 0.560
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.442 0.558
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.442 0.558
M31.8 Other specified necrotising vasculopathies
0.000 0.443 0.557
M31.7 Microscopic polyangiitis
0.000 0.443 0.557
M31.4 Aortic arch syndrome [Takayasu]
0.000 0.443 0.557
M31.2 Lethal midline granuloma
0.000 0.443 0.557
I23 Certain current complications following acute myocardial infarction
0.000 0.445 0.555
M00-M03 Infectious arthropathies
0.000 0.445 0.554
E78.8 Other disorders of lipoprotein metabolism
0.000 0.445 0.555
M30.8 Other conditions related to polyarteritis nodosa
0.000 0.448 0.552
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]
0.000 0.448 0.552
M30.2 Juvenile polyarteritis
0.000 0.448 0.552
M10 Gout
0.000 0.450 0.549
H35.5 Hereditary retinal dystrophy
0.000 0.452 0.548
M82.1 Osteoporosis in endocrine disorders
0.000 0.453 0.547
I70 Atherosclerosis
0.000 0.454 0.546
H61 Other disorders of external ear
0.000 0.458 0.542
E80.6 Other disorders of bilirubin metabolism
0.000 0.458 0.542
H43.2 Crystalline deposits in vitreous body
0.000 0.460 0.540
I12.0 Hypertensive renal disease with renal failure
0.000 0.460 0.540
M35.0 Sicca syndrome [Sjogren]
0.000 0.462 0.538
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.463 0.537
E80.5 Crigler-Najjar syndrome
0.000 0.463 0.537
E80.3 Defects of catalase and peroxydase
0.000 0.463 0.537
E80.1 Porphyria cutanea tarda
0.000 0.463 0.537
E80.0 Hereditary erythropoietic porphyria
0.000 0.463 0.537
M65.19 Other infective (teno)synovitis (Site unspecified)
0.000 0.463 0.536
M65.18 Other infective (teno)synovitis (Other)
0.000 0.463 0.536
M65.17 Other infective (teno)synovitis (Ankle and foot)
0.000 0.463 0.536
M65.16 Other infective (teno)synovitis (Lower leg)
0.000 0.463 0.536
M65.15 Other infective (teno)synovitis (Pelvic region and thigh)
0.000 0.463 0.536
M65.13 Other infective (teno)synovitis (Forearm)
0.000 0.463 0.536
M65.12 Other infective (teno)synovitis (Upper arm)
0.000 0.463 0.536
M65.11 Other infective (teno)synovitis (Shoulder region)
0.000 0.463 0.536
M65.10 Other infective (teno)synovitis (Multiple sites)
0.000 0.463 0.536
G36.0 Neuromyelitis optica [Devic]
0.534 0.466 0.000
M66.0 Rupture of popliteal cyst
0.000 0.467 0.533
L85.8 Other specified epidermal thickening
0.000 0.468 0.532
I15.9 Seconday hypertension, unspecified
0.000 0.470 0.530
E83.8 Other disorders of mineral metabolism
0.239 0.472 0.289
E83.2 Disorders of zinc metabolism
0.239 0.472 0.289
E83.0 Disorders of copper metabolism
0.239 0.472 0.289
H40.0 Glaucoma suspect
0.000 0.473 0.527
M46 Other inflammatory spondylopathies
0.000 0.474 0.526
E89.2 Postprocedural hypoparathyroidism
0.000 0.475 0.525
H33.3 Retinal breaks without detachment
0.000 0.477 0.523
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.477 0.523
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.479 0.521
M66.2 Spontaneous rupture of extensor tendons
0.000 0.481 0.519
G36.9 Acute disseminated demyelination, unspecified
0.518 0.482 0.000
G36.8 Other specified acute disseminated demyelination
0.518 0.482 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.518 0.482 0.000
H30.9 Chorioretinal inflammation, unspecified
0.000 0.484 0.516
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.484 0.515
M14.4 Arthropathy in amyloidosis
0.000 0.484 0.515
M14.3 Lipoid dermatoarthritis
0.000 0.484 0.515
M14.2 Diabetic arthropathy
0.000 0.484 0.515
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.484 0.515
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.484 0.515
E83.9 Disorder of mineral metabolism, unspecified
0.259 0.485 0.256
I21.9 Acute myocardial infarction, unspecified
0.000 0.485 0.515
L56.9 Acute skin change due to ultraviolet radiation, unspecified
0.000 0.485 0.514
H43.0 Vitreous prolapse
0.000 0.486 0.514
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.486 0.514
M06.18 Adult-onset Still's disease (Other)
0.000 0.486 0.514
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.486 0.514
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.486 0.514
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.486 0.514
M06.14 Adult-onset Still's disease (Hand)
0.000 0.486 0.514
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.486 0.514
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.486 0.514
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.486 0.514
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.486 0.514
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.486 0.514
M06.28 Rheumatoid bursitis (Other)
0.000 0.486 0.514
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.486 0.514
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.486 0.514
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.486 0.514
M06.24 Rheumatoid bursitis (Hand)
0.000 0.486 0.514
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.486 0.514

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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