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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1053924
log Bayes Factor = 133.698
Chromosome 6   position 32,120,715  (GRCh37) Explore rs1053924 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
I10 Essential (primary) hypertension
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.001 0.999
K51.9 Ulcerative colitis, unspecified
0.999 0.001 0.000
E14 Unspecified diabetes mellitus
0.000 0.001 0.999
E16.2 Hypoglycaemia, unspecified
0.000 0.002 0.998
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.004 0.996
E11.9 Without complications
0.000 0.006 0.994
E10.4 With neurological complications
0.000 0.009 0.991
E05.9 Thyrotoxicosis, unspecified
0.000 0.012 0.988
E11.1 With ketoacidosis
0.000 0.016 0.984
E14.3 With ophthalmic complications
0.000 0.018 0.982
K51 Ulcerative colitis
0.969 0.031 0.000
E14.9 Without complications
0.000 0.036 0.964
G35-G37 Demyelinating diseases of the central nervous system
0.959 0.041 0.000
J45.9 Asthma, unspecified
0.000 0.043 0.957
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.046 0.954
K51.3 Ulcerative (chronic) rectosigmoiditis
0.950 0.050 0.000
G37 Other demyelinating diseases of central nervous system
0.949 0.051 0.000
I10-I15 Hypertensive diseases
0.000 0.067 0.933
G37.9 Demyelinating disease of central nervous system, unspecified
0.922 0.078 0.000
E03.8 Other specified hypothyroidism
0.000 0.080 0.920
E11.3 With ophthalmic complications
0.000 0.081 0.919
E10.5 With peripheral circulatory complications
0.000 0.085 0.915
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.091 0.909
E10.0 With coma
0.000 0.103 0.897
E11.2 With renal complications
0.000 0.104 0.896
I12 Hypertensive renal disease
0.000 0.109 0.891
E13 Other specified diabetes mellitus
0.000 0.117 0.883
I15 Secondary hypertension
0.000 0.126 0.874
E10.2 With renal complications
0.000 0.135 0.865
E14.8 With unspecified complications
0.000 0.136 0.864
K51.4 Pseudopolyposis of colon
0.862 0.138 0.000
E10.8 With unspecified complications
0.000 0.141 0.859
E16.1 Other hypoglycaemia
0.000 0.152 0.848
K51.5 Mucosal proctocolitis
0.844 0.156 0.000
E07 Other disorders of thyroid
0.000 0.164 0.836
E14.4 With neurological complications
0.000 0.167 0.833
I12.9 Hypertensive renal disease without renal failure
0.000 0.179 0.821
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.817 0.183 0.000
E13.9 Without complications
0.000 0.186 0.814
K51.8 Other ulcerative colitis
0.807 0.193 0.000
E10.6 With other specified complications
0.000 0.196 0.803
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.197 0.803
G37.8 Other specified demyelinating diseases of central nervous system
0.800 0.199 0.000
I12.0 Hypertensive renal disease with renal failure
0.000 0.218 0.782
I15.9 Seconday hypertension, unspecified
0.000 0.223 0.777
E14.2 Withrenal complications
0.000 0.242 0.758
E11.6 With other specified complications
0.000 0.254 0.746
G36 Other acute disseminated demyelination
0.741 0.259 0.000
I15.1 Hypertension secondary to other renal disorders
0.000 0.265 0.735
E11.0 With coma
0.000 0.274 0.725
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E07.9 Disorder of thyroid, unspecified
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.716
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.716
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.716
E16.3 Increased secretion of glucagon
0.000 0.283 0.716
E14.7 With multiple complications
0.000 0.284 0.716
E14.1 With ketoacidosis
0.000 0.284 0.716
E14.0 With coma
0.000 0.284 0.716
E05.5 Thyroid crisis or storm
0.000 0.286 0.714
E05.4 Thyrotoxicosis factitia
0.000 0.286 0.714
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.286 0.714
E14.5 With peripheral circulatory complications
0.000 0.292 0.708
E03.1 Congenital hypothyroidism without goitre
0.000 0.293 0.707
E83.1 Disorders of iron metabolism
0.707 0.293 0.000
E10.7 With multiple complications
0.000 0.296 0.704
I15.0 Renovascular hypertension
0.000 0.319 0.681
G37.5 Concentric sclerosis [Balo]
0.681 0.319 0.000
G37.4 Subacute necrotising myelitis
0.681 0.319 0.000
G37.2 Central pontine myelinolysis
0.681 0.319 0.000
G37.1 Central demyelination of corpus callosum
0.681 0.319 0.000
G37.0 Diffuse sclerosis
0.681 0.319 0.000
E40-E46 Malnutrition
0.000 0.321 0.679
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.326 0.674
I13 Hypertensive heart and renal disease
0.000 0.331 0.669
E05.8 Other thyrotoxicosis
0.000 0.337 0.663
E11.5 With peripheral circulatory complications
0.000 0.349 0.651
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.352 0.647
E13.8 With unspecified complications
0.000 0.366 0.633
E13.7 With multiple complications
0.000 0.366 0.633
E13.6 With other specified complications
0.000 0.366 0.633
E13.5 With peripheral circulatory complications
0.000 0.366 0.633
E13.4 With neurological complications
0.000 0.366 0.633
E13.2 With renal complications
0.000 0.366 0.633
E13.1 With ketoacidosis
0.000 0.366 0.633
E13.0 With coma
0.000 0.366 0.633
I15.8 Other secondary hypertension
0.000 0.373 0.626
I15.2 Hypertension secondary to endocrine disorders
0.000 0.373 0.626
K51.1 Ulcerative (chronic) ileocolitis
0.611 0.389 0.000
E11.8 With unspecified complications
0.000 0.389 0.610
E07.8 Other specified disorders of thyroid
0.000 0.399 0.601
E07.1 Dyshormogenetic goitre
0.000 0.401 0.599
E07.0 Hypersecretion of calcitonin
0.000 0.401 0.599
E06 Thyroiditis
0.000 0.408 0.592
G36.0 Neuromyelitis optica [Devic]
0.585 0.415 0.000
E13.3 With ophthalmic complications
0.000 0.416 0.584
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.419 0.581
K51.2 Ulcerative (chronic) proctitis
0.579 0.421 0.000
E14.6 With other specified complications
0.000 0.423 0.577
E20-E35 Disorders of other endocrine glands
0.000 0.432 0.568
I11 Hypertensive heart disease
0.000 0.450 0.550
G36.9 Acute disseminated demyelination, unspecified
0.531 0.468 0.000
G36.8 Other specified acute disseminated demyelination
0.531 0.468 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.531 0.468 0.000
K90 Intestinal malabsorption
0.000 0.475 0.525
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.484 0.516
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E83 Disorders of mineral metabolism
0.512 0.488 0.000
E83.3 Disorders of phosphorus metabolism
0.500 0.500 0.000
E21.3 Hyperparathyroidism, unspecified
0.000 0.500 0.500
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.513 0.487
E45 Retarded development following protein-energy malnutrition
0.000 0.513 0.487
E43 Unspecified severe protein-energy malnutrition
0.000 0.513 0.487
E42 Marasmic kwashiorkor
0.000 0.513 0.487
E41 Nutritional marasmus
0.000 0.513 0.487
E40 Kwashiorkor
0.000 0.513 0.487
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.520 0.480
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.520 0.480
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.520 0.480
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.520 0.480
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.525 0.474
E23 Hypofunction and other disorders of pituitary gland
0.000 0.534 0.466
K90.9 Intestinal malabsorption, unspecified
0.000 0.538 0.462
E24 Cushing's syndrome
0.000 0.545 0.455
E46 Unspecified protein-energy malnutrition
0.000 0.551 0.449
K51.0 Ulcerative (chronic) enterocolitis
0.445 0.555 0.000
E28 Ovarian dysfunction
0.000 0.566 0.434
E06.5 Other chronic thyroiditis
0.000 0.575 0.424
E06.4 Drug-induced thyroiditis
0.000 0.575 0.424
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.575 0.424
E06.1 Subacute thyroiditis
0.000 0.575 0.424
E06.0 Acute thyroiditis
0.000 0.575 0.424
E23.2 Diabetes insipidus
0.000 0.583 0.417
E11.4 With neurological complications
0.000 0.587 0.413
E83.9 Disorder of mineral metabolism, unspecified
0.408 0.592 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.593 0.407
E32 Diseases of thymus
0.000 0.593 0.407
E30 Disorders of puberty, not elsewhere classified
0.000 0.593 0.407
E06.9 Thyroiditis, unspecified
0.000 0.602 0.398
E31 Polyglandular dysfunction
0.000 0.604 0.395
E29 Testicular dysfunction
0.000 0.605 0.395
Z93.2 Ileostomy status
0.395 0.605 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.606 0.394
E24.0 Pituitary-dependent Cushing's disease
0.000 0.612 0.388
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.615 0.385
E23.6 Other disorders of pituitary gland
0.000 0.619 0.380
K90.3 Pancreatic steatorrhoea
0.000 0.624 0.376
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.624 0.376
K90.1 Tropical sprue
0.000 0.624 0.376
E65-E68 Obesity and other hyperalimentation
0.000 0.628 0.372
E21.4 Other specified disorders of parathyroid gland
0.000 0.630 0.370
E83.8 Other disorders of mineral metabolism
0.367 0.633 0.000
E83.2 Disorders of zinc metabolism
0.367 0.633 0.000
E83.0 Disorders of copper metabolism
0.367 0.633 0.000
K90.8 Other intestinal malabsorption
0.000 0.637 0.363
L40.9 Psoriasis, unspecified
0.000 0.637 0.363
E23.7 Disorder of pituitary gland, unspecified
0.000 0.638 0.362
E21.2 Other hyperparathyroidism
0.000 0.643 0.357
E27 Other disorders of adrenal gland
0.000 0.643 0.357
L40 Psoriasis
0.000 0.645 0.355
E44.1 Mild protein-energy malnutrition
0.000 0.651 0.349
E44.0 Moderate protein-energy malnutrition
0.000 0.651 0.349
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.653 0.347
L40.5 Arthropathic psoriasis
0.000 0.655 0.345
E25 Adrenogenital disorders
0.000 0.657 0.343
E26 Hyperaldosteronism
0.000 0.657 0.343
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.660 0.340
E06.3 Autoimmune thyroiditis
0.000 0.660 0.340
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.666 0.334
E23.1 Drug-induced hypopituitarism
0.000 0.666 0.334
E28.2 Polycystic ovarian syndrome
0.000 0.671 0.328
L40.0 Psoriasis vulgaris
0.000 0.672 0.328
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.674 0.326
E24.3 Ectopic ACTH syndrome
0.000 0.674 0.326
E24.2 Drug-induced Cushing's syndrome
0.000 0.674 0.326
E24.1 Nelson's syndrome
0.000 0.674 0.326
E24.9 Cushing's syndrome, unspecified
0.000 0.678 0.321
E28.3 Primary ovarian failure
0.000 0.679 0.321
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.684 0.316
E28.9 Ovarian dysfunction, unspecified
0.000 0.689 0.311
E28.8 Other ovarian dysfunction
0.000 0.689 0.311
E28.1 Androgen excess
0.000 0.689 0.311
E28.0 Oestrogen excess
0.000 0.689 0.311
E22 Hyperfunction of pituitary gland
0.000 0.694 0.306
E24.8 Other Cushing's syndrome
0.000 0.697 0.303
E27.9 Disorder of adrenal gland, unspecified
0.000 0.697 0.303
E20 Hypoparathyroidism
0.000 0.704 0.296
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.704 0.296
E30.9 Disorder of puberty, unspecified
0.000 0.708 0.292
E30.8 Other disorders of puberty
0.000 0.708 0.292
E30.1 Precocious puberty
0.000 0.708 0.292
E30.0 Delayed puberty
0.000 0.708 0.292
E32.9 Disease of thymus, unspecified
0.000 0.708 0.292
E32.8 Other diseases of thymus
0.000 0.708 0.292
E32.1 Abscess of thymus
0.000 0.708 0.292
E32.0 Persistent hyperplasia of thymus
0.000 0.708 0.292
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.708 0.292
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.708 0.292
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.708 0.292
L40.1 Generalised pustular psoriasis
0.000 0.710 0.290
E31.9 Polyglandular dysfunction, unspecified
0.000 0.716 0.284
E31.8 Other polyglandular dysfunction
0.000 0.716 0.284
E31.1 Polyglandular hyperfunction
0.000 0.716 0.284
E29.9 Testicular dysfunction, unspecified
0.000 0.717 0.283
E29.8 Other testicular dysfunction
0.000 0.717 0.283
E29.0 Testicular hyperfunction
0.000 0.717 0.283
E50-E64 Other nutritional deficiencies
0.000 0.723 0.277
E31.0 Autoimmune polyglandular failure
0.000 0.728 0.272
E29.1 Testicular hypofunction
0.000 0.729 0.271
E67 Other hyperalimentation
0.000 0.733 0.267
E68 Sequelae of hyperalimentation
0.000 0.733 0.267
E27.8 Other specified disorders of adrenal gland
0.000 0.735 0.265
E34 Other endocrine disorders
0.000 0.740 0.259
L40.3 Pustulosis palmaris et plantaris
0.000 0.742 0.258
E27.5 Adrenomedullary hyperfunction
0.000 0.744 0.256
E27.0 Other adrenocortical overactivity
0.000 0.744 0.256
L40.4 Guttate psoriasis
0.000 0.745 0.255
L40.2 Acrodermatitis continua
0.000 0.745 0.255
H36.0 Diabetic retinopathy
0.000 0.753 0.247
E25.9 Adrenogenital disorder, unspecified
0.000 0.754 0.246
E25.8 Other adrenogenital disorders
0.000 0.754 0.246
E26.8 Other hyperaldosteronism
0.000 0.754 0.246
E26.1 Secondary hyperaldosteronism
0.000 0.754 0.246
E22.1 Hyperprolactinaemia
0.000 0.757 0.243
L40.8 Other psoriasis
0.000 0.764 0.236
E65 Localised adiposity
0.000 0.772 0.228
E83.4 Disorders of magnesium metabolism
0.227 0.773 0.000
E26.9 Hyperaldosteronism, unspecified
0.000 0.774 0.226
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.780 0.220
E22.8 Other hyperfunction of pituitary gland
0.000 0.780 0.220
E20.1 Pseudohypoparathyroidism
0.000 0.787 0.212
E20.0 Idiopathic hypoparathyroidism
0.000 0.787 0.212
E26.0 Primary hyperaldosteronism
0.000 0.792 0.208
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.801 0.199
E63 Other nutritional deficiencies
0.000 0.801 0.199
E50 Vitamin A deficiency
0.000 0.801 0.199
E60 Dietary zinc deficiency
0.000 0.801 0.199
E59 Dietary selenium deficiency
0.000 0.801 0.199
E54 Ascorbic acid deficiency
0.000 0.801 0.199
E52 Niacin deficiency [pellagra]
0.000 0.801 0.199
E27.2 Addisonian crisis
0.000 0.802 0.198
E51 Thiamine deficiency
0.000 0.804 0.196
E67.8 Other specified hyperalimentation
0.000 0.808 0.191
E67.3 Hypervitaminosis D
0.000 0.808 0.191
E67.2 Megavitamin-B6 syndrome
0.000 0.808 0.191
E67.1 Hypercarotenaemia
0.000 0.808 0.191
E67.0 Hypervitaminosis A
0.000 0.808 0.191
E34.8 Other specified endocrine disorders
0.000 0.809 0.191
E56 Other vitamin deficiencies
0.001 0.813 0.186
E34.5 Androgen resistance syndrome
0.000 0.814 0.186
E34.4 Constitutional tall stature
0.000 0.814 0.186
E34.3 Short stature, not elsewhere classified
0.000 0.814 0.186
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.814 0.186
E34.1 Other hypersecretion of intestinal hormones
0.000 0.814 0.186
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.001 0.818 0.182
E20.8 Other hypoparathyroidism
0.001 0.818 0.182
E58 Dietary calcium deficiency
0.001 0.818 0.181
E61 Deficiency of other nutrient elements
0.000 0.820 0.180
E83.5 Disorders of calcium metabolism
0.175 0.825 0.000
J45 Asthma
0.000 0.828 0.171
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.832 0.168
M45.X9 Ankylosing spondylitis (Site unspecified)
0.162 0.838 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.842 0.158
E22.0 Acromegaly and pituitary gigantism
0.000 0.844 0.156
E20.9 Hypoparathyroidism, unspecified
0.001 0.846 0.153
E34.0 Carcinoid syndrome
0.001 0.852 0.148
E50.9 Vitamin A deficiency, unspecified
0.000 0.857 0.143
E50.8 Other manifestations of vitamin A deficiency
0.000 0.857 0.143
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.857 0.143
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.857 0.143
E50.5 Vitamin A deficiency with night blindness
0.000 0.857 0.143
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.857 0.143
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.857 0.143
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.857 0.143
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.857 0.143
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.857 0.143
E63.9 Nutritional deficiency, unspecified
0.000 0.857 0.143
E63.8 Other specified nutritional deficiencies
0.000 0.857 0.143
E63.1 Imbalance of constituents of food intake
0.000 0.857 0.143
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.857 0.143
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.857 0.143
E64.8 Sequelae of other nutritional deficiencies
0.000 0.857 0.143
E64.3 Sequelae of rickets
0.000 0.857 0.143
E64.2 Sequelae of vitamin C deficiency
0.000 0.857 0.143
E64.1 Sequelae of vitamin A deficiency
0.000 0.857 0.143
E64.0 Sequelae of protein-energy malnutrition
0.000 0.857 0.143
E51.9 Thiamine deficiency, unspecified
0.000 0.859 0.141
E51.8 Other manifestations of thiamine deficiency
0.000 0.859 0.141
E51.1 Beriberi
0.000 0.859 0.141
E51.2 Wernicke's encephalopathy
0.000 0.862 0.138
E56.9 Vitamin deficiency, unspecified
0.001 0.866 0.134
E56.8 Deficiency of other vitamins
0.001 0.866 0.134
E56.0 Deficiency of vitamin E
0.001 0.866 0.134
E53 Deficiency of other B group vitamins
0.000 0.869 0.131
E61.9 Deficiency of nutrient element, unspecified
0.000 0.871 0.129
E61.8 Deficiency of other specified nutrient elements
0.000 0.871 0.129
E61.7 Deficiency of multiple nutrient elements
0.000 0.871 0.129
E61.6 Vanadium deficiency
0.000 0.871 0.129
E61.5 Molybdenum deficiency
0.000 0.871 0.129
E61.4 Chromium deficiency
0.000 0.871 0.129
E61.3 Manganese deficiency
0.000 0.871 0.129
E61.0 Copper deficiency
0.000 0.871 0.129
D64.9 Anaemia, unspecified
0.000 0.871 0.129
E55 Vitamin D deficiency
0.001 0.875 0.124
H36 Retinal disorders in diseases classified elsewhere
0.000 0.875 0.125
E56.1 Deficiency of vitamin K
0.001 0.878 0.121
E61.1 Iron deficiency
0.000 0.879 0.121
E61.2 Magnesium deficiency
0.000 0.879 0.120
E21.0 Primary hyperparathyroidism
0.000 0.880 0.120
E04 Other non-toxic goitre
0.000 0.882 0.118
J45.1 Nonallergic asthma
0.000 0.882 0.117
M45 Ankylosing spondylitis
0.112 0.888 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.893 0.107
J45.8 Mixed asthma
0.000 0.894 0.106
E34.9 Endocrine disorder, unspecified
0.001 0.895 0.104
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.101 0.899 0.000
E53.1 Pyridoxine deficiency
0.000 0.906 0.094
E53.0 Riboflavin deficiency
0.000 0.906 0.094
L40-L45 Papulosquamous disorders
0.000 0.909 0.091
E55.0 Rickets, active
0.001 0.910 0.089
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.910 0.089
K50-K52 Noninfective enteritis and colitis
0.087 0.912 0.000
E04.8 Other specified non-toxic goitre
0.000 0.915 0.085
E23.0 Hypopituitarism
0.001 0.915 0.084
M95.0 Acquired deformity of nose
0.083 0.917 0.000
E04.0 Non-toxic diffuse goitre
0.000 0.918 0.082
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.081 0.919 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.081 0.919 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.081 0.919 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.081 0.919 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.081 0.919 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.081 0.919 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.081 0.919 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.080 0.920 0.000
E53.8 Deficiency of other specified B group vitamins
0.000 0.921 0.078
L44 Other papulosquamous disorders
0.000 0.934 0.065
L41 Parapsoriasis
0.000 0.934 0.065
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.934 0.065
E53.9 Vitamin B deficiency, unspecified
0.001 0.942 0.057
L42 Pityriasis rosea
0.000 0.944 0.056
E04.1 Non-toxic single thyroid nodule
0.000 0.944 0.056
L43 Lichen planus
0.000 0.948 0.052
D64 Other anaemias
0.000 0.949 0.051
E70-E90 Metabolic disorders
0.009 0.949 0.043
J45.0 Predominantly allergic asthma
0.000 0.950 0.050
L41.9 Parapsoriasis, unspecified
0.000 0.953 0.047
L41.8 Other parapsoriasis
0.000 0.953 0.047
L41.5 Retiform parapsoriasis
0.000 0.953 0.047
L41.4 Large plaque parapsoriasis
0.000 0.953 0.047
L41.3 Small plaque parapsoriasis
0.000 0.953 0.047
L41.2 Lymphomatoid papulosis
0.000 0.953 0.047
L41.1 Pityriasis lichenoides chronica
0.000 0.953 0.047
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.953 0.047
L44.9 Papulosquamous disorder, unspecified
0.000 0.953 0.047
L44.8 Other specified papulosquamous disorders
0.000 0.953 0.047
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.953 0.047
L44.3 Lichen ruber moniliformis
0.000 0.953 0.047
L44.2 Lichen striatus
0.000 0.953 0.047
L44.1 Lichen nitidus
0.000 0.953 0.047
L44.0 Pityriasis rubra pilaris
0.000 0.953 0.047
K72 Hepatic failure, not elsewhere classified
0.000 0.956 0.044
K70-K77 Diseases of liver
0.000 0.956 0.044
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.001 0.956 0.043
E66 Obesity
0.000 0.956 0.043
K70 Alcoholic liver disease
0.000 0.957 0.043
K90-K93 Other diseases of the digestive system
0.000 0.957 0.043
K72.0 Acute and subacute hepatic failure
0.000 0.958 0.042
K73 Chronic hepatitis, not elsewhere classified
0.000 0.958 0.042
K70.1 Alcoholic hepatitis
0.000 0.959 0.041
E89.0 Postprocedural hypothyroidism
0.000 0.960 0.040
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.961 0.039
K75 Other inflammatory liver diseases
0.000 0.961 0.039
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.001 0.962 0.038
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.038 0.962 0.000
K72.9 Hepatic failure, unspecified
0.000 0.962 0.038
L43.3 Subacute (active) lichen planus
0.000 0.962 0.037
L43.2 Lichenoid drug reaction
0.000 0.962 0.037
L43.1 Bullous lichen planus
0.000 0.962 0.037
L43.0 Hypertrophic lichen planus
0.000 0.962 0.037
H30-H36 Disorders of choroid and retina
0.000 0.963 0.037
D64.4 Congenital dyserythropoietic anaemia
0.000 0.963 0.037
D64.3 Other sideroblastic anaemias
0.000 0.963 0.037
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.963 0.037
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.963 0.037
D64.0 Hereditary sideroblastic anaemia
0.000 0.963 0.037
E77 Disorders of glycoprotein metabolism
0.006 0.963 0.031
E76 Disorders of glycosaminoglycan metabolism
0.006 0.963 0.031
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.006 0.963 0.031
E70 Disorders of aromatic amino-acid metabolism
0.006 0.963 0.031
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.006 0.963 0.031
M20.1 Hallux valgus (acquired)
0.037 0.963 0.000
E89.2 Postprocedural hypoparathyroidism
0.000 0.963 0.036
H34.8 Other retinal vascular occlusions
0.000 0.963 0.037
K70.3 Alcoholic cirrhosis of liver
0.000 0.964 0.036
H34 Retinal vascular occlusions
0.000 0.964 0.036
E72 Other disorders of amino-acid metabolism
0.006 0.964 0.029
E74 Other disorders of carbohydrate metabolism
0.006 0.964 0.030
K72.1 Chronic hepatic failure
0.000 0.965 0.035
K73.9 Chronic hepatitis, unspecified
0.000 0.965 0.035
K70.0 Alcoholic fatty liver
0.000 0.965 0.035
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.006 0.965 0.028
E79 Disorders of purine and pyrimidine metabolism
0.007 0.966 0.028
K75.8 Other specified inflammatory liver diseases
0.000 0.966 0.034
K70.4 Alcoholic hepatic failure
0.000 0.967 0.033
E73 Lactose intolerance
0.006 0.967 0.027
L43.9 Lichen planus, unspecified
0.000 0.967 0.033
K75.4 Autoimmune hepatitis
0.000 0.967 0.032
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.968 0.032
E89.3 Postprocedural hypopituitarism
0.001 0.968 0.031
K77 Liver disorders in diseases classified elsewhere
0.000 0.968 0.032
E88 Other metabolic disorders
0.004 0.968 0.028
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.001 0.968 0.031
E89.8 Other postprocedural endocrine and metabolic disorders
0.001 0.968 0.031
E89.5 Postprocedural testicular hypofunction
0.001 0.968 0.031
E66.1 Drug-induced obesity
0.000 0.968 0.031
K74 Fibrosis and cirrhosis of liver
0.000 0.969 0.031
E85 Amyloidosis
0.006 0.969 0.026
E84 Cystic fibrosis
0.007 0.969 0.024
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.969 0.031
L43.8 Other lichen planus
0.000 0.969 0.031
J47 Bronchiectasis
0.031 0.969 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.006 0.970 0.024
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.970 0.030
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.970 0.030
E89.1 Postprocedural hypoinsulinaemia
0.001 0.970 0.029
K70.2 Alcoholic fibrosis and sclerosis of liver
0.000 0.970 0.030
K71 Toxic liver disease
0.000 0.970 0.030
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.970 0.030
K70.9 Alcoholic liver disease, unspecified
0.000 0.970 0.030
K75.0 Abscess of liver
0.000 0.970 0.030
M95.3 Acquired deformity of neck
0.029 0.971 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.971 0.029
K50 Crohn's disease [regional enteritis]
0.029 0.971 0.000
H34.9 Retinal vascular occlusion, unspecified
0.000 0.971 0.029
D64.8 Other specified anaemias
0.000 0.972 0.028
K75.2 Nonspecific reactive hepatitis
0.000 0.972 0.028
K75.1 Phlebitis of portal vein
0.000 0.972 0.028
M95.9 Acquired deformity of musculoskeletal system, unspecified
0.027 0.972 0.000
M95.8 Other specified acquired deformities of musculoskeletal system
0.027 0.972 0.000
M95.5 Acquired deformity of pelvis
0.027 0.972 0.000
M95.1 Cauliflower ear
0.027 0.972 0.000
K74.0 Hepatic fibrosis
0.000 0.973 0.027
K50.1 Crohn's disease of large intestine
0.027 0.973 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.973 0.027
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.005 0.973 0.022
E70.8 Other disorders of aromatic amino-acid metabolism
0.005 0.973 0.022
E70.3 Albinism
0.005 0.973 0.022
E70.2 Disorders of tyrosine metabolism
0.005 0.973 0.022
E70.1 Other hyperphenylalaninaemias
0.005 0.973 0.022
E70.0 Classical phenylketonuria
0.005 0.973 0.022
E71.3 Disorders of fatty-acid metabolism
0.005 0.973 0.022
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.005 0.973 0.022
E71.1 Other disorders of branched-chain amino-acid metabolism
0.005 0.973 0.022
E71.0 Maple-syrup-urine disease
0.005 0.973 0.022
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.005 0.973 0.022
E76.8 Other disorders of glucosaminoglycan metabolism
0.005 0.973 0.022
E76.3 Mucopolysaccharidosis, unspecified
0.005 0.973 0.022
E76.2 Other mucopolysaccharidoses
0.005 0.973 0.022
E76.1 Mucopolysaccharidosis, type II
0.005 0.973 0.022
E76.0 Mucopolysaccharidosis, type I
0.005 0.973 0.022
E77.9 Disorder of glycoprotein metabolism, unspecified
0.005 0.973 0.022
E77.8 Other disorders of glycoprotein metabolism
0.005 0.973 0.022

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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