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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant cluster associations

Hospitalization Episode Statistics (HES)

Cluster X0109
log Bayes Factor = 257.685
contains 11 variants:
rs115725122
lBF = 17.488
Chr 1 : 115,955,917
rs76328823
lBF = 13.032
Chr 5 : 68,061,720
rs34463898
lBF = 19.829
Chr 6 : 73,430,067
rs75033941
lBF = 14.410
Chr 7 : 15,616,587
rs2804609
lBF = 22.681
Chr10 : 113,847,037
rs78321382
lBF = 14.032
Chr12 : 17,070,922
rs117704155
lBF = 14.049
Chr14 : 37,850,007
rs77457385
lBF = 15.440
Chr15 : 69,979,587
rs117891146
lBF = 16.740
Chr17 : 77,212,307
rs79204427
lBF = 15.015
Chr18 : 47,693,130
rs73156729
lBF = 24.002
Chr22 : 31,319,187
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
G47.3 Sleep apnoea
1.000 0.000 0.000
G47 Sleep disorders
1.000 0.000 0.000
C15-C26 Malignant neoplasms of digestive organs
1.000 0.000 0.000
E70-E90 Metabolic disorders
1.000 0.000 0.000
G40-G47 Episodic and paroxysmal disorders
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
M70-M79 Other soft tissue disorders
1.000 0.000 0.000
O60-O75 Complications of labour and delivery
1.000 0.000 0.000
S00-S09 Injuries to the head
1.000 0.000 0.000
W00-W19 Falls
1.000 0.000 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
K59.0 Constipation
1.000 0.000 0.000
M13.99 Arthritis, unspecified (Site unspecified)
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
1.000 0.000 0.000
F31 Bipolar affective disorder
1.000 0.000 0.000
M25 Other joint disorders, not elsewhere classified
1.000 0.000 0.000
G90-G99 Other disorders of the nervous system
1.000 0.000 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
1.000 0.000 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
1.000 0.000 0.000
M06 Other rheumatoid arthritis
1.000 0.000 0.000
M79 Other soft tissue disorders, not elsewhere classified
1.000 0.000 0.000
S01 Open wound of head
1.000 0.000 0.000
T81 Complications of procedures, not elsewhere classified
1.000 0.000 0.000
F30-F39 Mood [affective] disorders
1.000 0.000 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
1.000 0.000 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
1.000 0.000 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
1.000 0.000 0.000
S20-S29 Injuries to the thorax
1.000 0.000 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
1.000 0.000 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
1.000 0.000 0.000
N93.9 Abnormal uterine and vaginal bleeding, unspecified
1.000 0.000 0.000
H30-H36 Disorders of choroid and retina
1.000 0.000 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
1.000 0.000 0.000
S00 Superficial injury of head
1.000 0.000 0.000
S80-S89 Injuries to the knee and lower leg
1.000 0.000 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
1.000 0.000 0.000
K70-K77 Diseases of liver
1.000 0.000 0.000
M13 Other arthritis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
Chapter XXII Codes for special purposes
1.000 0.000 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
1.000 0.000 0.000
M10 Gout
1.000 0.000 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
1.000 0.000 0.000
C15 Malignant neoplasm of oesophagus
1.000 0.000 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
1.000 0.000 0.000
I71 Aortic aneurysm and dissection
1.000 0.000 0.000
M10.9 Gout, unspecified
1.000 0.000 0.000
Z29 Need for other prophylactic measures
1.000 0.000 0.000
S02 Fracture of skull and facial bones
1.000 0.000 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.999 0.001 0.000
G93 Other disorders of brain
0.999 0.001 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.999 0.001 0.000
M13.9 Arthritis, unspecified
0.999 0.001 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.999 0.001 0.000
J44 Other chronic obstructive pulmonary disease
0.999 0.001 0.000
E83 Disorders of mineral metabolism
0.999 0.001 0.000
S60-S69 Injuries to the wrist and hand
0.999 0.001 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.999 0.001 0.000
L60-L75 Disorders of skin appendages
0.999 0.001 0.000
K59 Other functional intestinal disorders
0.999 0.001 0.000
J40-J47 Chronic lower respiratory diseases
0.999 0.001 0.000
I05-I09 Chronic rheumatic heart diseases
0.999 0.001 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.999 0.001 0.000
E10 Insulin-dependent diabetes mellitus
0.999 0.001 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.999 0.001 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.998 0.002 0.000
U80 Agent resistant to penicillin and related antibiotics
0.998 0.002 0.000
Z46 Fitting and adjustment of other devices
0.998 0.002 0.000
W19 Unspecified fall
0.998 0.002 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.998 0.002 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.998 0.002 0.000
R00.0 Tachycardia, unspecified
0.998 0.002 0.000
I87 Other disorders of veins
0.998 0.002 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.998 0.002 0.000
N93 Other abnormal uterine and vaginal bleeding
0.998 0.002 0.000
G20-G26 Extrapyramidal and movement disorders
0.998 0.002 0.000
B95-B98 Bacterial, viral and other infectious agents
0.998 0.002 0.000
G40 Epilepsy
0.998 0.002 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.998 0.002 0.000
K55-K64 Other diseases of intestines
0.997 0.003 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.997 0.003 0.000
N10-N16 Renal tubulo-interstitial diseases
0.997 0.003 0.000
S06 Intracranial injury
0.997 0.003 0.000
D00-D09 In situ neoplasms
0.997 0.003 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.997 0.003 0.000
S90-S99 Injuries to the ankle and foot
0.997 0.003 0.000
N13 Obstructive and reflux uropathy
0.997 0.003 0.000
H35 Other retinal disorders
0.997 0.003 0.000
I05 Rheumatic mitral valve diseases
0.997 0.003 0.000
T90 Sequelae of injuries of head
0.997 0.003 0.000
R00 Abnormalities of heart beat
0.996 0.004 0.000
D03 Melanoma in situ
0.996 0.004 0.000
H55-H59 Other disorders of eye and adnexa
0.996 0.004 0.000
S40-S49 Injuries to the shoulder and upper arm
0.996 0.004 0.000
K86 Other diseases of pancreas
0.996 0.004 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.996 0.004 0.000
H43-H45 Disorders of vitreous body and globe
0.996 0.004 0.000
N00-N08 Glomerular diseases
0.996 0.004 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.996 0.004 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.996 0.004 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.996 0.004 0.000
C51-C58 Malignant neoplasms of female genital organs
0.995 0.005 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.995 0.005 0.000
S01.5 Open wound of lip and oral cavity
0.995 0.005 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.994 0.006 0.000
M10.99 Gout, unspecified (Site unspecified)
0.994 0.006 0.000
I74 Arterial embolism and thrombosis
0.994 0.006 0.000
K11 Diseases of salivary glands
0.994 0.006 0.000
N20-N23 Urolithiasis
0.994 0.006 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.994 0.006 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.994 0.006 0.000
Z35 Supervision of high-risk pregnancy
0.994 0.006 0.000
M80-M85 Disorders of bone density and structure
0.993 0.007 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.993 0.007 0.000
K70 Alcoholic liver disease
0.993 0.007 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.993 0.007 0.000
F20 Schizophrenia
0.993 0.007 0.000
K50-K52 Noninfective enteritis and colitis
0.993 0.007 0.000
M79.0 Rheumatism, unspecified
0.993 0.007 0.000
C15.5 Lower third of oesophagus
0.993 0.007 0.000
N20 Calculus of kidney and ureter
0.993 0.007 0.000
R26 Abnormalities of gait and mobility
0.992 0.008 0.000
H57 Other disorders of eye and adnexa
0.992 0.008 0.000
F31.9 Bipolar affective disorder, unspecified
0.992 0.008 0.000
E20-E35 Disorders of other endocrine glands
0.992 0.008 0.000
I34 Nonrheumatic mitral valve disorders
0.992 0.008 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.991 0.009 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.991 0.009 0.000
Q60-Q64 Congenital malformations of the urinary system
0.991 0.009 0.000
Z46.8 Fitting and adjustment of other specified devices
0.991 0.009 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.991 0.009 0.000
M79.1 Myalgia
0.991 0.009 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.991 0.009 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.990 0.010 0.000
J90-J94 Other diseases of pleura
0.990 0.010 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.990 0.010 0.000
J95-J99 Other diseases of the respiratory system
0.990 0.010 0.000
I34.1 Mitral (valve) prolapse
0.989 0.011 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.989 0.011 0.000
E86 Volume depletion
0.989 0.011 0.000
W19.4 Street and highway
0.988 0.012 0.000
E50-E64 Other nutritional deficiencies
0.988 0.012 0.000
E83.3 Disorders of phosphorus metabolism
0.988 0.012 0.000
G62 Other polyneuropathies
0.988 0.012 0.000
R01 Cardiac murmurs and other cardiac sounds
0.988 0.012 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.988 0.012 0.000
C71 Malignant neoplasm of brain
0.987 0.013 0.000
N20.0 Calculus of kidney
0.987 0.013 0.000
K50 Crohn's disease [regional enteritis]
0.987 0.013 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.987 0.013 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.987 0.013 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.986 0.014 0.000
M45-M49 Spondylopathies
0.986 0.014 0.000
C91 Lymphoid leukaemia
0.986 0.014 0.000
N03 Chronic nephritic syndrome
0.986 0.014 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.985 0.015 0.000
M50-M54 Other dorsopathies
0.985 0.015 0.000
M25.8 Other specified joint disorders
0.985 0.015 0.000
I50 Heart failure
0.985 0.015 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.985 0.015 0.000
K70.9 Alcoholic liver disease, unspecified
0.985 0.015 0.000
I50.1 Left ventricular failure
0.985 0.015 0.000
U80.1 Methicillin resistant agent
0.985 0.015 0.000
Z50 Care involving use of rehabilitation procedures
0.985 0.015 0.000
N71 Inflammatory disease of uterus, except cervix
0.984 0.016 0.000
S69 Other and unspecified injuries of wrist and hand
0.984 0.016 0.000
S22.3 Fracture of rib
0.984 0.016 0.000
M65-M68 Disorders of synovium and tendon
0.984 0.016 0.000
I42 Cardiomyopathy
0.984 0.016 0.000
K82 Other diseases of gallbladder
0.984 0.016 0.000
F05.9 Delirium, unspecified
0.984 0.016 0.000
F20.9 Schizophrenia, unspecified
0.983 0.017 0.000
M86-M90 Other osteopathies
0.983 0.017 0.000
D03.5 Melanoma in situ of trunk
0.983 0.017 0.000
K74 Fibrosis and cirrhosis of liver
0.983 0.017 0.000
L73 Other follicular disorders
0.983 0.017 0.000
M21 Other acquired deformities of limbs
0.983 0.017 0.000
C56 Malignant neoplasm of ovary
0.982 0.018 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.982 0.018 0.000
E10.3 With ophthalmic complications
0.981 0.019 0.000
S80 Superficial injury of lower leg
0.981 0.019 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.980 0.020 0.000
H43 Disorders of vitreous body
0.980 0.020 0.000
L20-L30 Dermatitis and eczema
0.980 0.020 0.000
S20 Superficial injury of thorax
0.980 0.020 0.000
J09-J18 Influenza and pneumonia
0.980 0.020 0.000
S50-S59 Injuries to the elbow and forearm
0.980 0.020 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.979 0.021 0.000
G62.9 Polyneuropathy, unspecified
0.979 0.021 0.000
A00-A09 Intestinal infectious diseases
0.979 0.021 0.000
Z33 Pregnant state, incidental
0.979 0.021 0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract
0.979 0.021 0.000
S10-S19 Injuries to the neck
0.979 0.021 0.000
Y44 Agents primarily affecting blood constituents
0.979 0.021 0.000
N03.9 Unspecified
0.978 0.022 0.000
I35 Nonrheumatic aortic valve disorders
0.978 0.022 0.000
Z50.8 Care involving use of rehabilitation procedures
0.978 0.022 0.000
M77 Other enthesopathies
0.978 0.022 0.000
R25 Abnormal involuntary movements
0.978 0.022 0.000
S22.30 Fracture of rib (closed)
0.978 0.022 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.977 0.023 0.000
Z22 Carrier of infectious disease
0.977 0.023 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.977 0.023 0.000
H34 Retinal vascular occlusions
0.977 0.023 0.000
Q80-Q89 Other congenital malformations
0.976 0.024 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.976 0.024 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.975 0.025 0.000
Z29.0 Isolation
0.975 0.025 0.000
M54 Dorsalgia
0.975 0.025 0.000
M54.2 Cervicalgia
0.975 0.025 0.000
G20 Parkinson's disease
0.975 0.025 0.000
N17-N19 Renal failure
0.974 0.026 0.000
C25 Malignant neoplasm of pancreas
0.974 0.026 0.000
G93.8 Other specified disorders of brain
0.974 0.026 0.000
G30-G32 Other degenerative diseases of the nervous system
0.974 0.026 0.000
R01.0 Benign and innocent cardiac murmurs
0.974 0.026 0.000
M24 Other specific joint derangements
0.974 0.026 0.000
S00.9 Superficial injury of head, part unspecified
0.973 0.027 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.973 0.027 0.000
J95.8 Other postprocedural respiratory disorders
0.973 0.027 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.973 0.027 0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters
0.973 0.027 0.000
A30-A49 Other bacterial diseases
0.972 0.028 0.000
C15.9 Oesophagus, unspecified
0.972 0.028 0.000
I72 Other aneurysm
0.972 0.028 0.000
M65 Synovitis and tenosynovitis
0.972 0.028 0.000
M79.00 Rheumatism, unspecified (Multiple sites)
0.972 0.028 0.000
N71.9 Inflammatory disease of uterus, unspecified
0.971 0.029 0.000
Y52 Agents primarily affecting the cardiovascular system
0.971 0.029 0.000
Z29.2 Other prophylactic chemotherapy
0.971 0.029 0.000
M84 Disorders of continuity of bone
0.971 0.029 0.000
J00-J06 Acute upper respiratory infections
0.971 0.029 0.000
E83.1 Disorders of iron metabolism
0.970 0.030 0.000
L60 Nail disorders
0.970 0.030 0.000
K86.2 Cyst of pancreas
0.970 0.030 0.000
M54.22 Cervicalgia (Cervical region)
0.970 0.030 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.969 0.031 0.000
S69.9 Unspecified injury of wrist and hand
0.969 0.031 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.969 0.031 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.969 0.031 0.000
I05.0 Mitral stenosis
0.968 0.032 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.968 0.032 0.000
V10-V19 Pedal cyclist injured in transport accident
0.968 0.032 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.968 0.032 0.000
I87.2 Venous insufficiency (chronic) (peripheral)
0.967 0.033 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.967 0.033 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.967 0.033 0.000
S02.0 Fracture of vault of skull
0.966 0.034 0.000
I81 Portal vein thrombosis
0.966 0.034 0.000
J90 Pleural effusion, not elsewhere classified
0.966 0.034 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.966 0.034 0.000
O75.8 Other specified complications of labour and delivery
0.965 0.035 0.000
Q61 Cystic kidney disease
0.965 0.035 0.000
I05.9 Mitral valve disease, unspecified
0.965 0.035 0.000
C91.1 Chronic lymphocytic leukaemia
0.965 0.035 0.000
O66 Other obstructed labour
0.964 0.036 0.000
Z22.3 Carrier of other specified bacterial diseases
0.964 0.036 0.000
K12 Stomatitis and related lesions
0.963 0.037 0.000
Y44.2 Anticoagulants
0.963 0.037 0.000
R80 Isolated proteinuria
0.962 0.038 0.000
H57.9 Disorder of eye and adnexa, unspecified
0.962 0.038 0.000
E83.4 Disorders of magnesium metabolism
0.962 0.038 0.000
O16 Unspecified maternal hypertension
0.961 0.039 0.000
S42 Fracture of shoulder and upper arm
0.961 0.039 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.961 0.039 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.961 0.039 0.000
D47.2 Monoclonal gammopathy
0.961 0.039 0.000
S06.0 Concussion
0.961 0.039 0.000
O44 Placenta praevia
0.960 0.040 0.000
Z39 Postpartum care and examination
0.960 0.040 0.000
R82 Other abnormal findings in urine
0.960 0.040 0.000
A08 Viral and other specified intestinal infections
0.960 0.040 0.000
U80.0 Penicillin resistant agent
0.960 0.040 0.000
W07 Fall involving chair
0.959 0.041 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.959 0.041 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.959 0.041 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.959 0.041 0.000
G93.6 Cerebral oedema
0.959 0.041 0.000
Z34 Supervision of normal pregnancy
0.959 0.041 0.000
I33 Acute and subacute endocarditis
0.958 0.042 0.000
I35.1 Aortic (valve) insufficiency
0.958 0.042 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.958 0.042 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.957 0.043 0.000
M79.19 Myalgia (Site unspecified)
0.957 0.043 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.956 0.044 0.000
W06 Fall involving bed
0.956 0.044 0.000
W19.2 School, other institution and public administrative area
0.956 0.044 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.956 0.044 0.000
E87.2 Acidosis
0.955 0.045 0.000
O32.1 Maternal care for breech presentation
0.955 0.045 0.000
I71.0 Dissection of aorta [any part]
0.955 0.045 0.000
I51 Complications and ill-defined descriptions of heart disease
0.955 0.045 0.000
I86 Varicose veins of other sites
0.955 0.045 0.000
K86.9 Disease of pancreas, unspecified
0.954 0.046 0.000
N94.9 Unspecified condition associated with female genital organs and menstrual cycle
0.954 0.046 0.000
G41 Status epilepticus
0.954 0.046 0.000
S82 Fracture of lower leg, including ankle
0.954 0.046 0.000
C64-C68 Malignant neoplasms of urinary tract
0.954 0.046 0.000
F33 Recurrent depressive disorder
0.954 0.046 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.953 0.047 0.000
O85-O92 Complications predominantly related to the puerperium
0.953 0.047 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.953 0.047 0.000
K50.8 Other Crohn's disease
0.953 0.047 0.000
S02.8 Fractures of other skull and facial bones
0.953 0.047 0.000
R50-R69 General symptoms and signs
0.952 0.048 0.000
Z35.1 Supervision of pregnancy with history of abortive outcome
0.952 0.048 0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.952 0.048 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.952 0.048 0.000
K11.8 Other diseases of salivary glands
0.952 0.048 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.952 0.048 0.000
S20.2 Contusion of thorax
0.952 0.048 0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.951 0.049 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.951 0.049 0.000
Z63 Other problems related to primary support group, including family circumstances
0.951 0.049 0.000
R90.0 Intracranial space-occupying lesion
0.951 0.049 0.000
E53 Deficiency of other B group vitamins
0.951 0.049 0.000
O75.7 Vaginal delivery following previous Caesarean section
0.950 0.050 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.949 0.051 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.948 0.052 0.000
E10.4 With neurological complications
0.948 0.052 0.000
Z32 Pregnancy examination and test
0.948 0.052 0.000
G44 Other headache syndromes
0.948 0.052 0.000
N94.8 Other specified conditions associated with female genital organs and menstrual cycle
0.947 0.053 0.000
C18 Malignant neoplasm of colon
0.947 0.053 0.000
S00.1 Contusion of eyelid and periocular area
0.947 0.053 0.000
L27 Dermatitis due to substances taken internally
0.947 0.053 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.946 0.054 0.000
J00 Acute nasopharyngitis [common cold]
0.946 0.054 0.000
Y42.7 Androgens and anabolic congeners
0.946 0.054 0.000
H44 Disorders of globe
0.946 0.054 0.000
F29 Unspecified nonorganic psychosis
0.946 0.054 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.945 0.055 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.945 0.055 0.000
S27 Injury of other and unspecified intrathoracic organs
0.945 0.055 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.944 0.056 0.000
A08.4 Viral intestinal infection, unspecified
0.943 0.057 0.000
M70.4 Prepatellar bursitis
0.943 0.057 0.000
E22 Hyperfunction of pituitary gland
0.943 0.057 0.000
R52 Pain, not elsewhere classified
0.942 0.058 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.942 0.058 0.000
S02.00 Fracture of vault of skull (closed)
0.942 0.058 0.000
H35.7 Separation of retinal layers
0.942 0.058 0.000
Z34.9 Supervision of normal pregnancy, unspecified
0.942 0.058 0.000
I51.7 Cardiomegaly
0.942 0.058 0.000
K82.1 Hydrops of gallbladder
0.941 0.059 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.941 0.059 0.000
S51 Open wound of forearm
0.941 0.059 0.000
S22.2 Fracture of sternum
0.940 0.060 0.000
O20 Haemorrhage in early pregnancy
0.940 0.060 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.940 0.060 0.000
S01.2 Open wound of nose
0.940 0.060 0.000
I87.1 Compression of vein
0.940 0.060 0.000
M25.9 Joint disorder, unspecified
0.939 0.061 0.000
S70-S79 Injuries to the hip and thigh
0.939 0.061 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.938 0.062 0.000
N76 Other inflammation of vagina and vulva
0.938 0.062 0.000
H35.6 Retinal haemorrhage
0.938 0.062 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.937 0.063 0.000
S62 Fracture at wrist and hand level
0.937 0.063 0.000
C21 Malignant neoplasm of anus and anal canal
0.936 0.064 0.000
M34 Systemic sclerosis
0.936 0.064 0.000
N18 Chronic renal failure
0.936 0.064 0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.936 0.064 0.000
E27 Other disorders of adrenal gland
0.936 0.064 0.000
Q85 Phakomatoses, not elsewhere classified
0.936 0.064 0.000
V80-V89 Other land transport accidents
0.936 0.064 0.000
E10.2 With renal complications
0.936 0.064 0.000
N20.9 Urinary calculus, unspecified
0.936 0.064 0.000
L73.2 Hidradenitis suppurativa
0.936 0.064 0.000
Z45 Adjustment and management of implanted device
0.935 0.065 0.000
S06.00 Concussion (without open intracranial wound)
0.935 0.065 0.000
G58 Other mononeuropathies
0.935 0.065 0.000
I99 Other and unspecified disorders of circulatory system
0.935 0.065 0.000
G24 Dystonia
0.935 0.065 0.000
Y40 Systemic antibiotics
0.934 0.066 0.000
H52 Disorders of refraction and accommodation
0.934 0.066 0.000
Y43 Primarily systemic agents
0.934 0.066 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.934 0.066 0.000
F60-F69 Disorders of adult personality and behaviour
0.934 0.066 0.000
N17 Acute renal failure
0.934 0.066 0.000
S02.1 Fracture of base of skull
0.934 0.066 0.000
M21.1 Varus deformity, not elsewhere classified
0.934 0.066 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.933 0.067 0.000
S01.0 Open wound of scalp
0.933 0.067 0.000
T90.9 Sequelae of unspecified injury of head
0.933 0.067 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.933 0.067 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.933 0.067 0.000
D03.3 Melanoma in situ of other and unspecified parts of face
0.933 0.067 0.000
H21 Other disorders of iris and ciliary body
0.932 0.068 0.000
O44.1 Placenta praevia with haemorrhage
0.932 0.068 0.000
I87.8 Other specified disorders of veins
0.931 0.069 0.000
S93.1 Dislocation of toe(s)
0.930 0.070 0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)
0.930 0.070 0.000
N13.4 Hydroureter
0.930 0.070 0.000
Z45.1 Adjustment and management of infusion pump
0.930 0.070 0.000
O66.0 Obstructed labour due to shoulder dystocia
0.929 0.071 0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system
0.929 0.071 0.000
M25.7 Osteophyte
0.929 0.071 0.000
H36 Retinal disorders in diseases classified elsewhere
0.929 0.071 0.000
D04 Carcinoma in situ of skin
0.929 0.071 0.000
I33.0 Acute and subacute infective endocarditis
0.929 0.071 0.000
L71 Rosacea
0.929 0.071 0.000
I08 Multiple valve diseases
0.929 0.071 0.000
B65-B83 Helminthiases
0.928 0.072 0.000
K59.1 Functional diarrhoea
0.928 0.072 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.928 0.072 0.000
S01.7 Multiple open wounds of head
0.928 0.072 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.928 0.072 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.928 0.072 0.000
R27 Other lack of coordination
0.927 0.073 0.000
I77 Other disorders of arteries and arterioles
0.927 0.073 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.927 0.073 0.000
K11.5 Sialolithiasis
0.926 0.074 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.926 0.074 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.926 0.074 0.000
M88 Paget's disease of bone [osteitis deformans]
0.926 0.074 0.000
C92 Myeloid leukaemia
0.926 0.074 0.000
M79.7 Fibromyalgia
0.926 0.074 0.000
G95 Other diseases of spinal cord
0.925 0.075 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.925 0.075 0.000
W06.0 Home
0.925 0.075 0.000
S89 Other and unspecified injuries of lower leg
0.924 0.076 0.000
M91-M94 Chondropathies
0.924 0.076 0.000
D10-D36 Benign neoplasms
0.924 0.076 0.000
E53.8 Deficiency of other specified B group vitamins
0.924 0.076 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.923 0.077 0.000
C71.9 Brain, unspecified
0.923 0.077 0.000
T98 Sequelae of other and unspecified effects of external causes
0.923 0.077 0.000
G40.8 Other epilepsy
0.923 0.077 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.923 0.077 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.923 0.077 0.000
K11.2 Sialoadenitis
0.922 0.078 0.000
H52.2 Astigmatism
0.922 0.078 0.000
Z01.5 Diagnostic skin and sensitisation tests
0.922 0.078 0.000
Z46.5 Fitting and adjustment of ileostomy and other intestinal appliances
0.922 0.078 0.000
Z46.2 Fitting and adjustment of other devices related to nervous system and special senses
0.922 0.078 0.000
K58 Irritable bowel syndrome
0.922 0.078 0.000
K86.0 Alcohol-induced chronic pancreatitis
0.922 0.078 0.000
R52.0 Acute pain
0.922 0.078 0.000
S02.3 Fracture of orbital floor
0.922 0.078 0.000
H35.0 Background retinopathy and retinal vascular changes
0.922 0.078 0.000
G41.9 Status epilepticus, unspecified
0.922 0.078 0.000
S80.1 Contusion of other and unspecified parts of lower leg
0.922 0.078 0.000
M54.29 Cervicalgia-Site unspe
0.921 0.079 0.000
N82 Fistulae involving female genital tract
0.921 0.079 0.000
C16 Malignant neoplasm of stomach
0.921 0.079 0.000
M47 Spondylosis
0.921 0.079 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.920 0.080 0.000
N18.3 Chronic kidney disease, stage 3
0.920 0.080 0.000
I74.5 Embolism and thrombosis of iliac artery
0.920 0.080 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.920 0.080 0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes
0.919 0.081 0.000
S02.80 Fractures of other skull and facial bones (closed)
0.919 0.081 0.000
M25.84 Other specified joint disorders (Hand)
0.919 0.081 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.918 0.082 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.918 0.082 0.000
Z71.9 Counselling, unspecified
0.918 0.082 0.000
H57.1 Ocular pain
0.918 0.082 0.000
G93.0 Cerebral cysts
0.918 0.082 0.000
O43 Placental disorders
0.917 0.083 0.000
V18.2 Unspecified pedal cyclist injured in nontraffic accident
0.917 0.083 0.000
K74.0 Hepatic fibrosis
0.917 0.083 0.000
D26 Other benign neoplasms of uterus
0.917 0.083 0.000
M70.46 Prepatellar bursitis-Lower Leg
0.917 0.083 0.000
N91 Absent, scanty and rare menstruation
0.917 0.083 0.000
Z01.9 Special examination, unspecified
0.916 0.084 0.000
R52.2 Other chronic pain
0.916 0.084 0.000
M25.74 Osteophyte (Hand)
0.916 0.084 0.000
C71.1 Frontal lobe
0.916 0.084 0.000
S81 Open wound of lower leg
0.915 0.085 0.000
L73.9 Follicular disorder, unspecified
0.915 0.085 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.915 0.085 0.000
R56 Convulsions, not elsewhere classified
0.915 0.085 0.000
C25.0 Head of pancreas
0.914 0.086 0.000
I27 Other pulmonary heart diseases
0.914 0.086 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.913 0.087 0.000
F80-F89 Disorders of psychological development
0.912 0.088 0.000
S82.2 Fracture of shaft of tibia
0.912 0.088 0.000
C67 Malignant neoplasm of bladder
0.912 0.088 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.911 0.089 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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