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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78321382
log Bayes Factor = 14.0322
Chromosome 12   position 17,070,922  (GRCh37) Explore rs78321382 on Ensembl!
Variant rs78321382 is part of Cluster X0109

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
0.999 0.001 0.000
Chapter XIV Diseases of the genitourinary system
0.998 0.002 0.000
J40-J47 Chronic lower respiratory diseases
0.998 0.002 0.000
Chapter IX Diseases of the circulatory system
0.996 0.004 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.994 0.006 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.994 0.006 0.000
J44 Other chronic obstructive pulmonary disease
0.992 0.008 0.000
Chapter VI Diseases of the nervous system
0.991 0.009 0.000
M05-M14 Inflammatory polyarthropathies
0.989 0.011 0.000
N17-N19 Renal failure
0.988 0.012 0.000
I30-I52 Other forms of heart disease
0.987 0.013 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.980 0.020 0.000
W00-W19 Falls
0.980 0.020 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.970 0.030 0.000
Chapter I Certain infectious and parasitic diseases
0.955 0.045 0.000
M06 Other rheumatoid arthritis
0.955 0.045 0.000
N17 Acute renal failure
0.951 0.049 0.000
J30-J39 Other diseases of upper respiratory tract
0.946 0.054 0.000
N60-N64 Disorders of breast
0.945 0.055 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.938 0.062 0.000
I50 Heart failure
0.936 0.064 0.000
Chapter VII Diseases of the eye and adnexa
0.934 0.066 0.000
W07 Fall involving chair
0.930 0.070 0.000
G20-G26 Extrapyramidal and movement disorders
0.930 0.070 0.000
G40-G47 Episodic and paroxysmal disorders
0.930 0.070 0.000
M06.9 Rheumatoid arthritis, unspecified
0.927 0.073 0.000
E70-E90 Metabolic disorders
0.927 0.073 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.926 0.074 0.000
N17.9 Acute renal failure, unspecified
0.925 0.075 0.000
Y43 Primarily systemic agents
0.924 0.076 0.000
N20-N23 Urolithiasis
0.920 0.080 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.918 0.082 0.000
N10-N16 Renal tubulo-interstitial diseases
0.915 0.085 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.915 0.085 0.000
H30-H36 Disorders of choroid and retina
0.912 0.088 0.000
Chapter VIII Diseases of the ear and mastoid process
0.912 0.088 0.000
J34 Other disorders of nose and nasal sinuses
0.911 0.089 0.000
J09-J18 Influenza and pneumonia
0.911 0.089 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.910 0.090 0.000
N00-N08 Glomerular diseases
0.908 0.092 0.000
J45 Asthma
0.907 0.093 0.000
E50-E64 Other nutritional deficiencies
0.907 0.093 0.000
I05-I09 Chronic rheumatic heart diseases
0.906 0.094 0.000
Chapter V Mental and behavioural disorders
0.905 0.095 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.904 0.096 0.000
I47 Paroxysmal tachycardia
0.902 0.098 0.000
M10 Gout
0.895 0.105 0.000
S80-S89 Injuries to the knee and lower leg
0.895 0.105 0.000
M13 Other arthritis
0.894 0.106 0.000
G47 Sleep disorders
0.890 0.110 0.000
W19 Unspecified fall
0.890 0.110 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.887 0.113 0.000
I10-I15 Hypertensive diseases
0.884 0.116 0.000
H35 Other retinal disorders
0.884 0.116 0.000
N18 Chronic renal failure
0.883 0.117 0.000
N13 Obstructive and reflux uropathy
0.874 0.126 0.000
F30-F39 Mood [affective] disorders
0.870 0.130 0.000
R50-R69 General symptoms and signs
0.870 0.130 0.000
Y40 Systemic antibiotics
0.869 0.130 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.868 0.132 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.868 0.132 0.000
G20 Parkinson's disease
0.868 0.132 0.000
R26 Abnormalities of gait and mobility
0.867 0.133 0.000
I47.1 Supraventricular tachycardia
0.863 0.137 0.000
W07.0 Home
0.861 0.139 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.860 0.140 0.000
V10-V19 Pedal cyclist injured in transport accident
0.859 0.141 0.000
I27 Other pulmonary heart diseases
0.859 0.141 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.859 0.141 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.858 0.142 0.000
R25 Abnormal involuntary movements
0.856 0.144 0.000
N23 Unspecified renal colic
0.856 0.144 0.000
F31 Bipolar affective disorder
0.854 0.146 0.000
H90-H95 Other disorders of ear
0.853 0.147 0.000
E86 Volume depletion
0.852 0.148 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.848 0.152 0.000
N19 Unspecified renal failure
0.846 0.154 0.000
G90-G99 Other disorders of the nervous system
0.846 0.154 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.842 0.158 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.840 0.160 0.000
J40 Bronchitis, not specified as acute or chronic
0.840 0.160 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.839 0.161 0.000
G81 Hemiplegia
0.838 0.161 0.000
I34 Nonrheumatic mitral valve disorders
0.837 0.163 0.000
J34.2 Deviated nasal septum
0.835 0.165 0.000
S82 Fracture of lower leg, including ankle
0.833 0.167 0.000
M10.9 Gout, unspecified
0.828 0.172 0.000
S00-S09 Injuries to the head
0.828 0.172 0.000
N63 Unspecified lump in breast
0.828 0.172 0.000
I50.9 Heart failure, unspecified
0.827 0.173 0.000
N60 Benign mammary dysplasia
0.826 0.174 0.000
M13.9 Arthritis, unspecified
0.826 0.174 0.000
B07 Viral warts
0.817 0.183 0.000
G47.9 Sleep disorder, unspecified
0.816 0.184 0.000
M45-M49 Spondylopathies
0.815 0.185 0.000
Y43.3 Other antineoplastic drugs
0.815 0.185 0.000
F31.9 Bipolar affective disorder, unspecified
0.814 0.186 0.000
I27.2 Other secondary pulmonary hypertension
0.813 0.187 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.812 0.188 0.000
J18 Pneumonia, organism unspecified
0.810 0.190 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.808 0.192 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.807 0.193 0.000
I45 Other conduction disorders
0.807 0.193 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.807 0.193 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.804 0.196 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.804 0.196 0.000
S50-S59 Injuries to the elbow and forearm
0.802 0.198 0.000
E55 Vitamin D deficiency
0.802 0.198 0.000
R51 Headache
0.800 0.200 0.000
Y52 Agents primarily affecting the cardiovascular system
0.797 0.203 0.000
L40-L45 Papulosquamous disorders
0.797 0.203 0.000
W07.9 Unspecified place
0.796 0.204 0.000
I50.1 Left ventricular failure
0.796 0.204 0.000
I05 Rheumatic mitral valve diseases
0.795 0.205 0.000
H35.0 Background retinopathy and retinal vascular changes
0.795 0.205 0.000
I46 Cardiac arrest
0.794 0.206 0.000
R60 Oedema, not elsewhere classified
0.793 0.207 0.000
G81.9 Hemiplegia, unspecified
0.792 0.208 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.792 0.208 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.791 0.209 0.000
J45.9 Asthma, unspecified
0.790 0.210 0.000
N64 Other disorders of breast
0.788 0.212 0.000
R25.1 Tremor, unspecified
0.788 0.212 0.000
B35-B49 Mycoses
0.787 0.213 0.000
G47.3 Sleep apnoea
0.787 0.213 0.000
H35.9 Retinal disorder, unspecified
0.786 0.214 0.000
J43 Emphysema
0.785 0.215 0.000
J42 Unspecified chronic bronchitis
0.785 0.215 0.000
N18.3 Chronic kidney disease, stage 3
0.785 0.215 0.000
M50-M54 Other dorsopathies
0.784 0.216 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.784 0.216 0.000
S40-S49 Injuries to the shoulder and upper arm
0.783 0.217 0.000
J90-J94 Other diseases of pleura
0.780 0.220 0.000
I51 Complications and ill-defined descriptions of heart disease
0.777 0.223 0.000
H91 Other hearing loss
0.777 0.223 0.000
A00-A09 Intestinal infectious diseases
0.777 0.223 0.000
E53 Deficiency of other B group vitamins
0.776 0.224 0.000
R80 Isolated proteinuria
0.773 0.227 0.000
I50.0 Congestive heart failure
0.773 0.227 0.000
I10 Essential (primary) hypertension
0.770 0.230 0.000
W19.9 Unspecified place
0.770 0.230 0.000
J45.0 Predominantly allergic asthma
0.765 0.235 0.000
I44 Atrioventricular and left bundle-branch block
0.764 0.236 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.764 0.236 0.000
H10-H13 Disorders of conjunctiva
0.762 0.238 0.000
Y43.1 Antineoplastic antimetabolites
0.761 0.239 0.000
H43-H45 Disorders of vitreous body and globe
0.760 0.240 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.760 0.240 0.000
R69 Unknown and unspecified causes of morbidity
0.760 0.240 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.759 0.241 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.757 0.243 0.000
Chapter XXII Codes for special purposes
0.756 0.244 0.000
S20-S29 Injuries to the thorax
0.753 0.247 0.000
W19.4 Street and highway
0.753 0.247 0.000
M15-M19 Arthrosis
0.752 0.248 0.000
S01 Open wound of head
0.751 0.249 0.000
N04 Nephrotic syndrome
0.751 0.249 0.000
S70-S79 Injuries to the hip and thigh
0.751 0.249 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.749 0.251 0.000
I34.0 Mitral (valve) insufficiency
0.747 0.253 0.000
M91-M94 Chondropathies
0.747 0.253 0.000
R26.3 Immobility
0.746 0.254 0.000
B25-B34 Other viral diseases
0.745 0.255 0.000
H34 Retinal vascular occlusions
0.745 0.255 0.000
H33 Retinal detachments and breaks
0.745 0.255 0.000
Y40.0 Penicillins
0.745 0.255 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.744 0.256 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.744 0.256 0.000
M10.99 Gout, unspecified (Site unspecified)
0.744 0.256 0.000
S90-S99 Injuries to the ankle and foot
0.744 0.256 0.000
E88 Other metabolic disorders
0.743 0.257 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.742 0.258 0.000
G25 Other extrapyramidal and movement disorders
0.742 0.258 0.000
N21 Calculus of lower urinary tract
0.740 0.260 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.740 0.260 0.000
R82 Other abnormal findings in urine
0.740 0.260 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.738 0.262 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.738 0.262 0.000
J33 Nasal polyp
0.737 0.263 0.000
R27 Other lack of coordination
0.737 0.263 0.000
J18.0 Bronchopneumonia, unspecified
0.737 0.263 0.000
V80-V89 Other land transport accidents
0.736 0.264 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.734 0.266 0.000
N02 Recurrent and persistent haematuria
0.734 0.266 0.000
Y43.4 Immunosuppressive agents
0.732 0.267 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.732 0.268 0.000
G93 Other disorders of brain
0.731 0.269 0.000
Y45.2 Propionic acid derivatives
0.730 0.270 0.000
M05 Seropositive rheumatoid arthritis
0.729 0.271 0.000
I31 Other diseases of pericardium
0.729 0.271 0.000
I07 Rheumatic tricuspid valve diseases
0.728 0.272 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.728 0.272 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.728 0.272 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.728 0.272 0.000
M07 Psoriatic and enteropathic arthropathies
0.728 0.272 0.000
N03 Chronic nephritic syndrome
0.727 0.273 0.000
N13.6 Pyonephrosis
0.727 0.273 0.000
E55.9 Vitamin D deficiency, unspecified
0.726 0.274 0.000
R60.0 Localised oedema
0.726 0.274 0.000
S82.8 Fractures of other parts of lower leg
0.725 0.275 0.000
I60-I69 Cerebrovascular diseases
0.725 0.275 0.000
E87.0 Hyperosmolality and hypernatraemia
0.725 0.275 0.000
J60-J70 Lung diseases due to external agents
0.724 0.276 0.000
H55-H59 Other disorders of eye and adnexa
0.724 0.276 0.000
L43 Lichen planus
0.723 0.277 0.000
W06 Fall involving bed
0.722 0.277 0.000
R61 Hyperhidrosis
0.722 0.277 0.000
L20-L30 Dermatitis and eczema
0.722 0.278 0.000
H91.9 Hearing loss, unspecified
0.722 0.278 0.000
H35.8 Other specified retinal disorders
0.722 0.278 0.000
M18 Arthrosis of first carpometacarpal joint
0.721 0.279 0.000
S86 Injury of muscle and tendon at lower leg level
0.720 0.280 0.000
R47-R49 Symptoms and signs involving speech and voice
0.719 0.281 0.000
Y42.5 Other oestrogens and progestogens
0.719 0.281 0.000
X60-X84 Intentional self-harm
0.718 0.282 0.000
R04 Haemorrhage from respiratory passages
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.717 0.283 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
Y00-Y09 Assault
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.717 0.283 0.000
X50-X57 Overexertion, travel and privation
0.717 0.283 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X20-X29 Contact with venomous animals and plants
0.717 0.283 0.000
X10-X19 Contact with heat and hot substances
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.717 0.283 0.000
W75-W84 Other accidental threats to breathing
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
W50-W64 Exposure to animate mechanical forces
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V40-V49 Car occupant injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.717 0.283 0.000
M06.0 Seronegative rheumatoid arthritis
0.716 0.284 0.000
J41 Simple and mucopurulent chronic bronchitis
0.716 0.284 0.000
H35.6 Retinal haemorrhage
0.715 0.285 0.000
W13 Fall from, out of or through building or structure
0.715 0.285 0.000
A08 Viral and other specified intestinal infections
0.715 0.285 0.000
I00-I02 Acute rheumatic fever
0.714 0.285 0.000
B02 Zoster [herpes zoster]
0.714 0.286 0.000
Y59 Other and unspecified vaccines and biological substances
0.713 0.287 0.000
Y58 Bacterial vaccines
0.713 0.287 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.713 0.287 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.713 0.287 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.713 0.287 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.713 0.287 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.713 0.287 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.713 0.287 0.000
Y48 Anaesthetics and therapeutic gases
0.713 0.287 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.713 0.287 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.713 0.287 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.713 0.287 0.000
M60-M63 Disorders of muscles
0.712 0.287 0.000
M00-M03 Infectious arthropathies
0.712 0.287 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.712 0.288 0.000
Y57 Other and unspecified drugs and medicaments
0.712 0.288 0.000
N99-N99 Other disorders of the genitourinary system
0.712 0.288 0.000
W20-W49 Exposure to inanimate mechanical forces
0.711 0.289 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.711 0.289 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.711 0.289 0.000
M13.94 Arthritis, unspecified (Hand)
0.711 0.289 0.000
M14 Arthropathies in other diseases classified elsewhere
0.709 0.291 0.000
M12 Other specific arthropathies
0.709 0.291 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.709 0.291 0.000
M08 Juvenile arthritis
0.709 0.291 0.000
Y44 Agents primarily affecting blood constituents
0.708 0.292 0.000
I12 Hypertensive renal disease
0.708 0.292 0.000
I30 Acute pericarditis
0.708 0.292 0.000
R53 Malaise and fatigue
0.708 0.292 0.000
G70-G73 Diseases of myoneural junction and muscle
0.707 0.293 0.000
I52 Other heart disorders in diseases classified elsewhere
0.707 0.293 0.000
I48 Atrial fibrillation and flutter
0.707 0.293 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.707 0.293 0.000
I41 Myocarditis in diseases classified elsewhere
0.707 0.293 0.000
I40 Acute myocarditis
0.707 0.293 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.707 0.293 0.000
I37 Pulmonary valve disorders
0.707 0.293 0.000
I36 Nonrheumatic tricuspid valve disorders
0.707 0.293 0.000
I33 Acute and subacute endocarditis
0.707 0.293 0.000
I32 Pericarditis in diseases classified elsewhere
0.707 0.293 0.000
V20-V29 Motorcycle rider injured in transport accident
0.707 0.293 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.707 0.293 0.000
F60-F69 Disorders of adult personality and behaviour
0.705 0.295 0.000
M80-M85 Disorders of bone density and structure
0.705 0.295 0.000
M70-M79 Other soft tissue disorders
0.704 0.296 0.000
E40-E46 Malnutrition
0.704 0.296 0.000
R04.2 Haemoptysis
0.703 0.297 0.000
T79-T79 Certain early complications of trauma
0.703 0.297 0.000
T33-T35 Frostbite
0.703 0.297 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.703 0.297 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.703 0.297 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.703 0.297 0.000
T00-T07 Injuries involving multiple body regions
0.703 0.297 0.000
S10-S19 Injuries to the neck
0.703 0.297 0.000
W18 Other fall on same level
0.702 0.298 0.000
W17 Other fall from one level to another
0.702 0.298 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.702 0.298 0.000
W15 Fall from cliff
0.702 0.298 0.000
W14 Fall from tree
0.702 0.298 0.000
W12 Fall on and from scaffolding
0.702 0.298 0.000
W11 Fall on and from ladder
0.702 0.298 0.000
W10 Fall on and from stairs and steps
0.702 0.298 0.000
W09 Fall involving playground equipment
0.702 0.298 0.000
W08 Fall involving other furniture
0.702 0.298 0.000
W05 Fall involving wheelchair
0.702 0.298 0.000
W04 Fall while being carried or supported by other persons
0.702 0.298 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.702 0.298 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.702 0.298 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.702 0.298 0.000
W00 Fall on same level involving ice and snow
0.702 0.298 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.701 0.299 0.000
R25.2 Cramp and spasm
0.699 0.301 0.000
J18.9 Pneumonia, unspecified
0.699 0.301 0.000
S82.0 Fracture of patella
0.698 0.302 0.000
L40 Psoriasis
0.698 0.302 0.000
G30-G32 Other degenerative diseases of the nervous system
0.695 0.305 0.000
J20-J22 Other acute lower respiratory infections
0.695 0.305 0.000
N60.0 Solitary cyst of breast
0.694 0.306 0.000
E61 Deficiency of other nutrient elements
0.691 0.308 0.000
Y45.0 Opioids and related analgesics
0.691 0.309 0.000
M11 Other crystal arthropathies
0.690 0.309 0.000
I08 Multiple valve diseases
0.690 0.310 0.000
J32 Chronic sinusitis
0.689 0.310 0.000
N18.5 Chronic kidney disease, stage 5
0.689 0.311 0.000
G44 Other headache syndromes
0.688 0.312 0.000
N13.4 Hydroureter
0.686 0.313 0.000
H93 Other disorders of ear, not elsewhere classified
0.686 0.314 0.000
R54 Senility
0.686 0.314 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.685 0.314 0.000
Y40.8 Other systemic antibiotics
0.685 0.315 0.000
M47 Spondylosis
0.685 0.315 0.000
B99-B99 Other infectious diseases
0.685 0.315 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.685 0.315 0.000
B65-B83 Helminthiases
0.685 0.315 0.000
B50-B64 Protozoal diseases
0.685 0.315 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.685 0.315 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.685 0.315 0.000
A80-A89 Viral infections of the central nervous system
0.685 0.315 0.000
A75-A79 Rickettsioses
0.685 0.315 0.000
A70-A74 Other diseases caused by chlamydiae
0.685 0.315 0.000
A65-A69 Other spirochaetal diseases
0.685 0.315 0.000
A20-A28 Certain zoonotic bacterial diseases
0.685 0.315 0.000
A15-A19 Tuberculosis
0.685 0.315 0.000
E16 Other disorders of pancreatic internal secretion
0.685 0.315 0.000
M06.8 Other specified rheumatoid arthritis
0.684 0.315 0.000
M06.4 Inflammatory polyarthropathy
0.684 0.315 0.000
M06.3 Rheumatoid nodule
0.684 0.315 0.000
M06.2 Rheumatoid bursitis
0.684 0.315 0.000
M06.1 Adult-onset Still's disease
0.684 0.315 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.683 0.317 0.000
M10.94 Gout, unspecified (Hand)
0.683 0.317 0.000
H35.4 Peripheral retinal degeneration
0.683 0.317 0.000
S51 Open wound of forearm
0.683 0.317 0.000
E53.8 Deficiency of other specified B group vitamins
0.682 0.317 0.000
N17.8 Other acute renal failure
0.682 0.318 0.000
N17.2 Acute renal failure with medullary necrosis
0.682 0.318 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.682 0.318 0.000
N17.0 Acute renal failure with tubular necrosis
0.682 0.318 0.000
N05 Unspecified nephritic syndrome
0.682 0.318 0.000
F33 Recurrent depressive disorder
0.681 0.319 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.680 0.320 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.679 0.321 0.000
A30-A49 Other bacterial diseases
0.679 0.321 0.000
B15-B19 Viral hepatitis
0.679 0.321 0.000
M46 Other inflammatory spondylopathies
0.679 0.321 0.000
J34.3 Hypertrophy of nasal turbinates
0.678 0.322 0.000
J37 Chronic laryngitis and laryngotracheitis
0.678 0.322 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.678 0.322 0.000
I45.1 Other and unspecified right bundle-branch block
0.678 0.322 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.677 0.323 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.676 0.324 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.675 0.325 0.000
H90 Conductive and sensorineural hearing loss
0.674 0.326 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.674 0.326 0.000
S60-S69 Injuries to the wrist and hand
0.673 0.327 0.000
H65-H75 Diseases of middle ear and mastoid
0.673 0.327 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.673 0.327 0.000
H33.3 Retinal breaks without detachment
0.672 0.328 0.000
N25-N29 Other disorders of kidney and ureter
0.671 0.329 0.000
I27.9 Pulmonary heart disease, unspecified
0.671 0.329 0.000
A08.4 Viral intestinal infection, unspecified
0.670 0.330 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.670 0.330 0.000
H60-H62 Diseases of external ear
0.670 0.330 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.670 0.330 0.000
M86-M90 Other osteopathies
0.670 0.330 0.000
L43.9 Lichen planus, unspecified
0.670 0.330 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.670 0.330 0.000
J35 Chronic diseases of tonsils and adenoids
0.669 0.330 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.668 0.332 0.000
I05.2 Mitral stenosis with insufficiency
0.667 0.333 0.000
B37 Candidiasis
0.667 0.333 0.000
W07.2 School, other institution and public administrative area
0.667 0.333 0.000
W07.8 Other specified place
0.667 0.333 0.000
W07.7 Farm
0.667 0.333 0.000
W07.6 Industrial and construction area
0.667 0.333 0.000
W07.5 Trade and service area
0.667 0.333 0.000
W07.4 Street and highway
0.667 0.333 0.000
W07.3 Sports and athletics area
0.667 0.333 0.000
W07.1 Residential institution
0.667 0.333 0.000
G24 Dystonia
0.667 0.333 0.000
G23 Other degenerative diseases of basal ganglia
0.667 0.333 0.000
G21 Secondary Parkinsonism
0.667 0.333 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.667 0.333 0.000
G22 Parkinsonism in diseases classified elsewhere
0.667 0.333 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.667 0.333 0.000
G41 Status epilepticus
0.667 0.333 0.000
I38 Endocarditis, valve unspecified
0.665 0.335 0.000
N61 Inflammatory disorders of breast
0.665 0.335 0.000
S01.0 Open wound of scalp
0.665 0.335 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.665 0.335 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.665 0.335 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.665 0.335 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.665 0.335 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.665 0.335 0.000
J30 Vasomotor and allergic rhinitis
0.665 0.335 0.000
E85 Amyloidosis
0.664 0.336 0.000
E84 Cystic fibrosis
0.664 0.336 0.000
E79 Disorders of purine and pyrimidine metabolism
0.664 0.336 0.000
E77 Disorders of glycoprotein metabolism
0.664 0.336 0.000
E76 Disorders of glycosaminoglycan metabolism
0.664 0.336 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.664 0.336 0.000
E74 Other disorders of carbohydrate metabolism
0.664 0.336 0.000
E73 Lactose intolerance
0.664 0.336 0.000
E72 Other disorders of amino-acid metabolism
0.664 0.336 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.664 0.336 0.000
E70 Disorders of aromatic amino-acid metabolism
0.664 0.336 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.664 0.336 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.664 0.336 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.663 0.337 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.663 0.337 0.000
V18.2 Unspecified pedal cyclist injured in nontraffic accident
0.663 0.337 0.000
Y43.9 Primarily systemic agent, unspecified
0.663 0.337 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.663 0.337 0.000
Y43.6 Enzymes, not elsewhere classified
0.663 0.337 0.000
Y43.5 Acidifying and alkalising agents
0.663 0.337 0.000
Y43.2 Antineoplastic natural products
0.663 0.337 0.000
Y43.0 Antiallergic and antiemetic drugs
0.663 0.337 0.000
S82.6 Fracture of lateral malleolus
0.662 0.338 0.000
E87.7 Fluid overload
0.661 0.339 0.000
I67 Other cerebrovascular diseases
0.661 0.339 0.000
S01.5 Open wound of lip and oral cavity
0.660 0.340 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.659 0.341 0.000
M51 Other intervertebral disk disorders
0.659 0.341 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.659 0.341 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.656 0.344 0.000
N15 Other renal tubulo-interstitial diseases
0.656 0.344 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.656 0.344 0.000
N11 Chronic tubulo-interstitial nephritis
0.656 0.344 0.000
N10 Acute tubulo-interstitial nephritis
0.656 0.344 0.000
G82 Paraplegia and tetraplegia
0.656 0.344 0.000
I28 Other diseases of pulmonary vessels
0.656 0.344 0.000
T86 Failure and rejection of transplanted organs and tissues
0.656 0.344 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.656 0.344 0.000
I05.9 Mitral valve disease, unspecified
0.656 0.344 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.655 0.345 0.000
R52 Pain, not elsewhere classified
0.655 0.345 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.654 0.346 0.000
H31 Other disorders of choroid
0.654 0.346 0.000
H30 Chorioretinal inflammation
0.654 0.346 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.654 0.346 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.654 0.346 0.000
J34.1 Cyst and mucocele of nose and nasal sinus
0.653 0.347 0.000
J17 Pneumonia in diseases classified elsewhere
0.653 0.347 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.653 0.347 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.653 0.347 0.000
J12 Viral pneumonia, not elsewhere classified
0.653 0.347 0.000
J11 Influenza, virus not identified
0.653 0.347 0.000
J10 Influenza due to identified influenza virus
0.653 0.347 0.000
J14 Pneumonia due to Haemophilus influenzae
0.653 0.347 0.000
J09 Influenza due to certain identified influenza virus
0.653 0.347 0.000
N60.3 Fibrosclerosis of breast
0.651 0.349 0.000
I46.9 Cardiac arrest, unspecified
0.651 0.349 0.000
M13.93 Arthritis, unspecified (Forearm)
0.651 0.349 0.000
E20-E35 Disorders of other endocrine glands
0.651 0.349 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.651 0.349 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.651 0.349 0.000
N06 Isolated proteinuria with specified morphological lesion
0.651 0.349 0.000
N01 Rapidly progressive nephritic syndrome
0.651 0.349 0.000
N00 Acute nephritic syndrome
0.651 0.349 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.651 0.349 0.000
J45.8 Mixed asthma
0.650 0.349 0.000
J45.1 Nonallergic asthma
0.650 0.349 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.650 0.349 0.000
E63 Other nutritional deficiencies
0.650 0.349 0.000
E56 Other vitamin deficiencies
0.650 0.349 0.000
E51 Thiamine deficiency
0.650 0.349 0.000
E50 Vitamin A deficiency
0.650 0.349 0.000
E60 Dietary zinc deficiency
0.650 0.349 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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