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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77457385
log Bayes Factor = 15.4395
Chromosome 15   position 69,979,587  (GRCh37) Explore rs77457385 on Ensembl!
Variant rs77457385 is part of Cluster X0109

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.997 0.003 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.997 0.003 0.000
Chapter XX External causes of morbidity and mortality
0.996 0.004 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.996 0.004 0.000
Chapter IX Diseases of the circulatory system
0.995 0.005 0.000
Chapter XIV Diseases of the genitourinary system
0.994 0.006 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.993 0.007 0.000
M70-M79 Other soft tissue disorders
0.991 0.009 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.984 0.016 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.983 0.017 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.983 0.017 0.000
Chapter XI Diseases of the digestive system
0.982 0.018 0.000
Z92 Personal history of medical treatment
0.978 0.022 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.973 0.027 0.000
K90-K93 Other diseases of the digestive system
0.968 0.032 0.000
N95 Menopausal and other perimenopausal disorders
0.968 0.032 0.000
Z87 Personal history of other diseases and conditions
0.968 0.032 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.964 0.036 0.000
I30-I52 Other forms of heart disease
0.964 0.036 0.000
N84 Polyp of female genital tract
0.961 0.039 0.000
Z13 Special screening examination for other diseases and disorders
0.960 0.040 0.000
K92 Other diseases of digestive system
0.960 0.040 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.959 0.041 0.000
K70-K77 Diseases of liver
0.957 0.043 0.000
Z92.3 Personal history of irradiation
0.956 0.044 0.000
D60-D64 Aplastic and other anaemias
0.950 0.050 0.000
I51 Complications and ill-defined descriptions of heart disease
0.949 0.051 0.000
Z87.0 Personal history of diseases of the respiratory system
0.949 0.051 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.945 0.055 0.000
Z80 Family history of malignant neoplasm
0.942 0.058 0.000
Z13.6 Special screening examination for cardiovascular disorders
0.940 0.060 0.000
E65-E68 Obesity and other hyperalimentation
0.940 0.060 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.939 0.061 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.935 0.065 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.934 0.066 0.000
Chapter II Neoplasms
0.933 0.067 0.000
I51.7 Cardiomegaly
0.933 0.067 0.000
Z01.8 Other specified special examinations
0.933 0.067 0.000
N83.2 Other and unspecified ovarian cysts
0.932 0.068 0.000
N84.0 Polyp of corpus uteri
0.931 0.069 0.000
Chapter VI Diseases of the nervous system
0.931 0.069 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.930 0.070 0.000
E00-E07 Disorders of thyroid gland
0.924 0.076 0.000
O60-O75 Complications of labour and delivery
0.923 0.077 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.921 0.079 0.000
I20-I25 Ischaemic heart diseases
0.917 0.083 0.000
Z97 Presence of other devices
0.915 0.085 0.000
M05-M14 Inflammatory polyarthropathies
0.912 0.088 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.912 0.088 0.000
M75 Shoulder lesions
0.911 0.089 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.911 0.089 0.000
M77 Other enthesopathies
0.911 0.089 0.000
N95.2 Postmenopausal atrophic vaginitis
0.910 0.090 0.000
Z87.1 Personal history of diseases of the digestive system
0.909 0.091 0.000
I20 Angina pectoris
0.907 0.093 0.000
M50-M54 Other dorsopathies
0.907 0.093 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.904 0.096 0.000
E66 Obesity
0.902 0.098 0.000
Y83.8 Other surgical procedures
0.896 0.104 0.000
Z43 Attention to artificial openings
0.893 0.107 0.000
I20.9 Angina pectoris, unspecified
0.890 0.110 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.886 0.114 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.886 0.114 0.000
C15-C26 Malignant neoplasms of digestive organs
0.880 0.120 0.000
S80-S89 Injuries to the knee and lower leg
0.879 0.121 0.000
E66.9 Obesity, unspecified
0.878 0.122 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.878 0.122 0.000
N80 Endometriosis
0.873 0.127 0.000
I05-I09 Chronic rheumatic heart diseases
0.871 0.129 0.000
D61 Other aplastic anaemias
0.869 0.131 0.000
K76 Other diseases of liver
0.869 0.131 0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions
0.864 0.136 0.000
M72 Fibroblastic disorders
0.864 0.136 0.000
E10-E14 Diabetes mellitus
0.857 0.143 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.855 0.145 0.000
E05.9 Thyrotoxicosis, unspecified
0.853 0.147 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.851 0.149 0.000
K92.1 Melaena
0.851 0.149 0.000
Z51 Other medical care
0.848 0.152 0.000
M75.1 Rotator cuff syndrome
0.847 0.153 0.000
Y42.5 Other oestrogens and progestogens
0.845 0.155 0.000
Z80.4 Family history of malignant neoplasm of genital organs
0.843 0.157 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.843 0.157 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.840 0.160 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.840 0.160 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.839 0.161 0.000
N93 Other abnormal uterine and vaginal bleeding
0.837 0.163 0.000
M77.1 Lateral epicondylitis
0.837 0.163 0.000
I34 Nonrheumatic mitral valve disorders
0.836 0.164 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.836 0.164 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.834 0.166 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.833 0.167 0.000
K76.6 Portal hypertension
0.832 0.168 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.831 0.169 0.000
K70 Alcoholic liver disease
0.830 0.170 0.000
D50-D53 Nutritional anaemias
0.828 0.172 0.000
N92 Excessive, frequent and irregular menstruation
0.828 0.172 0.000
Chapter I Certain infectious and parasitic diseases
0.826 0.174 0.000
K74 Fibrosis and cirrhosis of liver
0.823 0.176 0.000
N95.3 States associated with artificial menopause
0.823 0.177 0.000
E50-E64 Other nutritional deficiencies
0.822 0.178 0.000
Z43.2 Attention to ileostomy
0.820 0.180 0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium
0.818 0.182 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.815 0.185 0.000
I20.0 Unstable angina
0.813 0.187 0.000
G40-G47 Episodic and paroxysmal disorders
0.812 0.188 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.812 0.188 0.000
W20-W49 Exposure to inanimate mechanical forces
0.812 0.188 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.811 0.189 0.000
D61.9 Aplastic anaemia, unspecified
0.811 0.189 0.000
Z04 Examination and observation for other reasons
0.810 0.189 0.000
Z51.2 Other chemotherapy
0.808 0.192 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.808 0.192 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.806 0.194 0.000
Z80.9 Family history of malignant neoplasm, unspecified
0.805 0.195 0.000
I35 Nonrheumatic aortic valve disorders
0.804 0.196 0.000
Z01.4 Gynaecological examination (general)(routine)
0.804 0.196 0.000
V10-V19 Pedal cyclist injured in transport accident
0.802 0.198 0.000
W00-W19 Falls
0.801 0.199 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.800 0.199 0.000
N95.8 Other specified menopausal and perimenopausal disorders
0.798 0.202 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.798 0.202 0.000
K30 Dyspepsia
0.794 0.206 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.794 0.206 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.793 0.207 0.000
K92.0 Haematemesis
0.793 0.207 0.000
Z01.5 Diagnostic skin and sensitisation tests
0.793 0.207 0.000
M50 Cervical disk disorders
0.792 0.208 0.000
M71 Other bursopathies
0.792 0.208 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.792 0.208 0.000
Z80.8 Family history of malignant neoplasm of other organs or systems
0.790 0.210 0.000
M54 Dorsalgia
0.790 0.210 0.000
Chapter V Mental and behavioural disorders
0.789 0.211 0.000
G47 Sleep disorders
0.787 0.213 0.000
Chapter X Diseases of the respiratory system
0.786 0.214 0.000
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified
0.786 0.214 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.784 0.216 0.000
M77.12 Lateral epicondylitis (Upper arm)
0.784 0.216 0.000
N85.2 Hypertrophy of uterus
0.784 0.216 0.000
Z97.0 Presence of artificial eye
0.781 0.219 0.000
D00-D09 In situ neoplasms
0.780 0.220 0.000
Y42.7 Androgens and anabolic congeners
0.780 0.220 0.000
M86-M90 Other osteopathies
0.779 0.221 0.000
N80.1 Endometriosis of ovary
0.778 0.222 0.000
M06 Other rheumatoid arthritis
0.777 0.222 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.777 0.223 0.000
G47.3 Sleep apnoea
0.777 0.223 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.776 0.224 0.000
M10 Gout
0.776 0.224 0.000
D62 Acute posthaemorrhagic anaemia
0.774 0.226 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.774 0.226 0.000
Z97.5 Presence of (intra-uterine) contraceptive device
0.773 0.227 0.000
Chapter XXII Codes for special purposes
0.773 0.227 0.000
Z13.9 Special screening examination, unspecified
0.772 0.228 0.000
C60-C63 Malignant neoplasms of male genital organs
0.770 0.230 0.000
I33 Acute and subacute endocarditis
0.769 0.231 0.000
N87 Dysplasia of cervix uteri
0.767 0.233 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.766 0.234 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.765 0.235 0.000
Z93 Artificial opening status
0.765 0.235 0.000
N00-N08 Glomerular diseases
0.764 0.235 0.000
Z43.6 Attention to other artificial openings of urinary tract
0.764 0.236 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.762 0.238 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.761 0.239 0.000
D64 Other anaemias
0.760 0.239 0.000
M75.3 Calcific tendinitis of shoulder
0.760 0.240 0.000
I05 Rheumatic mitral valve diseases
0.760 0.240 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.760 0.240 0.000
T66-T78 Other and unspecified effects of external causes
0.757 0.243 0.000
K75 Other inflammatory liver diseases
0.757 0.243 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.757 0.243 0.000
S81 Open wound of lower leg
0.756 0.244 0.000
V20-V29 Motorcycle rider injured in transport accident
0.755 0.245 0.000
K65-K67 Diseases of peritoneum
0.755 0.245 0.000
N83.1 Corpus luteum cyst
0.755 0.245 0.000
I38 Endocarditis, valve unspecified
0.754 0.246 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.754 0.246 0.000
I51.8 Other ill-defined heart diseases
0.752 0.248 0.000
I85 Oesophageal varices
0.751 0.248 0.000
N94.1 Dyspareunia
0.750 0.250 0.000
Z51.5 Palliative care
0.750 0.250 0.000
D80-D89 Certain disorders involving the immune mechanism
0.750 0.250 0.000
C15 Malignant neoplasm of oesophagus
0.748 0.251 0.000
Z53.9 Procedure not carried out, unspecified reason
0.748 0.252 0.000
C51-C58 Malignant neoplasms of female genital organs
0.746 0.254 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.745 0.255 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.744 0.256 0.000
N80.3 Endometriosis of pelvic peritoneum
0.742 0.258 0.000
O42 Premature rupture of membranes
0.742 0.258 0.000
N93.9 Abnormal uterine and vaginal bleeding, unspecified
0.742 0.258 0.000
V80-V89 Other land transport accidents
0.741 0.259 0.000
O80-O84 Delivery
0.741 0.259 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.740 0.260 0.000
M45-M49 Spondylopathies
0.740 0.260 0.000
I74 Arterial embolism and thrombosis
0.738 0.262 0.000
M05 Seropositive rheumatoid arthritis
0.737 0.263 0.000
Z97.8 Presence of other specified devices
0.735 0.265 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.735 0.265 0.000
N84.1 Polyp of cervix uteri
0.735 0.265 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.732 0.268 0.000
S89 Other and unspecified injuries of lower leg
0.732 0.268 0.000
O43 Placental disorders
0.731 0.269 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.728 0.272 0.000
S80 Superficial injury of lower leg
0.727 0.273 0.000
E07 Other disorders of thyroid
0.727 0.273 0.000
D69 Purpura and other haemorrhagic conditions
0.727 0.273 0.000
O16 Unspecified maternal hypertension
0.726 0.274 0.000
M40-M43 Deforming dorsopathies
0.726 0.274 0.000
E11 Non-insulin-dependent diabetes mellitus
0.726 0.274 0.000
O72 Postpartum haemorrhage
0.726 0.274 0.000
Z29 Need for other prophylactic measures
0.726 0.274 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.724 0.275 0.000
G62 Other polyneuropathies
0.724 0.276 0.000
Z80.3 Family history of malignant neoplasm of breast
0.724 0.276 0.000
N95.1 Menopausal and female climacteric states
0.723 0.277 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.722 0.278 0.000
Z71.8 Other specified counselling
0.721 0.279 0.000
N99-N99 Other disorders of the genitourinary system
0.720 0.280 0.000
Y52 Agents primarily affecting the cardiovascular system
0.719 0.281 0.000
E16 Other disorders of pancreatic internal secretion
0.718 0.281 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.716 0.283 0.000
Z10 Routine general health check-up of defined subpopulation
0.715 0.285 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.715 0.285 0.000
M91-M94 Chondropathies
0.715 0.285 0.000
M60-M63 Disorders of muscles
0.715 0.285 0.000
M00-M03 Infectious arthropathies
0.715 0.285 0.000
I34.1 Mitral (valve) prolapse
0.715 0.285 0.000
S82 Fracture of lower leg, including ankle
0.714 0.286 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.714 0.286 0.000
Y35-Y36 Legal intervention and operations of war
0.714 0.286 0.000
Y10-Y34 Event of undetermined intent
0.714 0.286 0.000
Y00-Y09 Assault
0.714 0.286 0.000
X85-X99 Assault
0.714 0.286 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.714 0.286 0.000
X50-X57 Overexertion, travel and privation
0.714 0.286 0.000
X30-X39 Exposure to forces of nature
0.714 0.286 0.000
X20-X29 Contact with venomous animals and plants
0.714 0.286 0.000
X10-X19 Contact with heat and hot substances
0.714 0.286 0.000
X00-X09 Exposure to smoke, fire and flames
0.714 0.286 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.714 0.286 0.000
W75-W84 Other accidental threats to breathing
0.714 0.286 0.000
W65-W74 Accidental drowning and submersion
0.714 0.286 0.000
W50-W64 Exposure to animate mechanical forces
0.714 0.286 0.000
V98-V99 Other and unspecified transport accidents
0.714 0.286 0.000
V95-V97 Air and space transport accidents
0.714 0.286 0.000
V90-V94 Water transport accidents
0.714 0.286 0.000
V70-V79 Bus occupant injured in transport accident
0.714 0.286 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.714 0.286 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.714 0.286 0.000
V40-V49 Car occupant injured in transport accident
0.714 0.286 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.714 0.286 0.000
V01-V09 Pedestrian injured in transport accident
0.714 0.286 0.000
N98 Complications associated with artificial fertilisation
0.714 0.286 0.000
N91 Absent, scanty and rare menstruation
0.714 0.286 0.000
N82 Fistulae involving female genital tract
0.714 0.286 0.000
N96 Habitual aborter
0.714 0.286 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.714 0.286 0.000
M75.9 Shoulder lesion, unspecified
0.713 0.286 0.000
I00-I02 Acute rheumatic fever
0.713 0.286 0.000
O66 Other obstructed labour
0.713 0.287 0.000
E40-E46 Malnutrition
0.712 0.288 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.712 0.288 0.000
N80.9 Endometriosis, unspecified
0.711 0.289 0.000
Z71.9 Counselling, unspecified
0.711 0.289 0.000
M77.4 Metatarsalgia
0.711 0.289 0.000
M76 Enthesopathies of lower limb, excluding foot
0.710 0.290 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.710 0.290 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.710 0.290 0.000
I51.9 Heart disease, unspecified
0.709 0.291 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.708 0.292 0.000
N92.6 Irregular menstruation, unspecified
0.708 0.292 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.707 0.293 0.000
M50.0 Cervical disk disorder with myelopathy
0.707 0.293 0.000
I30 Acute pericarditis
0.707 0.293 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.706 0.294 0.000
O48 Prolonged pregnancy
0.706 0.294 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.706 0.294 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.706 0.294 0.000
O85-O92 Complications predominantly related to the puerperium
0.705 0.295 0.000
Z87.4 Personal history of diseases of the genito-urinary system
0.705 0.295 0.000
Z50 Care involving use of rehabilitation procedures
0.705 0.295 0.000
D55-D59 Haemolytic anaemias
0.705 0.295 0.000
Z89 Acquired absence of limb
0.705 0.295 0.000
Z84 Family history of other conditions
0.705 0.295 0.000
Z81 Family history of mental and behavioural disorders
0.705 0.295 0.000
K25 Gastric ulcer
0.704 0.296 0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm
0.704 0.296 0.000
M54.5 Low back pain
0.704 0.296 0.000
Z48 Other surgical follow-up care
0.704 0.296 0.000
B25-B34 Other viral diseases
0.701 0.299 0.000
Z92.9 Personal history of medical treatment, unspecified
0.701 0.299 0.000
Z92.8 Personal history of other medical treatment
0.701 0.299 0.000
Z92.5 Personal history of rehabilitation measures
0.701 0.299 0.000
X60-X84 Intentional self-harm
0.701 0.299 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.700 0.300 0.000
N88 Other noninflammatory disorders of cervix uteri
0.700 0.300 0.000
D51 Vitamin B12 deficiency anaemia
0.699 0.301 0.000
I49 Other cardiac arrhythmias
0.699 0.301 0.000
C21 Malignant neoplasm of anus and anal canal
0.698 0.302 0.000
O69.1 Labour and delivery complicated by cord around neck, with compression
0.698 0.302 0.000
Z01.9 Special examination, unspecified
0.698 0.302 0.000
Z01.7 Laboratory examination
0.698 0.302 0.000
Z01.3 Examination of blood pressure
0.698 0.302 0.000
Z01.2 Dental examination
0.698 0.302 0.000
Z01.1 Examination of ears and hearing
0.698 0.302 0.000
Z01.0 Examination of eyes and vision
0.698 0.302 0.000
K74.6 Other and unspecified cirrhosis of liver
0.696 0.304 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.696 0.304 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.695 0.305 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.695 0.305 0.000
K90 Intestinal malabsorption
0.695 0.305 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.694 0.306 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.694 0.306 0.000
S90-S99 Injuries to the ankle and foot
0.694 0.306 0.000
N95.9 Menopausal and perimenopausal disorder, unspecified
0.694 0.306 0.000
Z87.6 Personal history of certain conditions arising in the perinatal period
0.694 0.306 0.000
Z09.8 Follow-up examination after other treatment for other conditions
0.693 0.307 0.000
I85.9 Oesophageal varices without bleeding
0.692 0.308 0.000
Y59 Other and unspecified vaccines and biological substances
0.691 0.309 0.000
Y58 Bacterial vaccines
0.691 0.309 0.000
Y57 Other and unspecified drugs and medicaments
0.691 0.309 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.691 0.309 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.691 0.309 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.691 0.309 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.691 0.309 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.691 0.309 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.691 0.309 0.000
Y48 Anaesthetics and therapeutic gases
0.691 0.309 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.691 0.309 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.691 0.309 0.000
Y44 Agents primarily affecting blood constituents
0.691 0.309 0.000
I52 Other heart disorders in diseases classified elsewhere
0.691 0.309 0.000
I48 Atrial fibrillation and flutter
0.691 0.309 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.691 0.309 0.000
I41 Myocarditis in diseases classified elsewhere
0.691 0.309 0.000
I40 Acute myocarditis
0.691 0.309 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.691 0.309 0.000
I37 Pulmonary valve disorders
0.691 0.309 0.000
I36 Nonrheumatic tricuspid valve disorders
0.691 0.309 0.000
I32 Pericarditis in diseases classified elsewhere
0.691 0.309 0.000
E61 Deficiency of other nutrient elements
0.690 0.310 0.000
O63 Long labour
0.690 0.310 0.000
M53 Other dorsopathies, not elsewhere classified
0.690 0.310 0.000
Z92.0 Personal history of contraception
0.690 0.310 0.000
N84.9 Polyp of female genital tract, unspecified
0.689 0.311 0.000
N84.8 Polyp of other parts of female genital tract
0.689 0.311 0.000
N84.3 Polyp of vulva
0.689 0.311 0.000
N84.2 Polyp of vagina
0.689 0.311 0.000
G70-G73 Diseases of myoneural junction and muscle
0.688 0.311 0.000
Z13.8 Special screening examination for other specified diseases and disorders
0.688 0.311 0.000
Z13.7 Special screening examination for congenital malformations, deformations and chromosomal abnormalities
0.688 0.311 0.000
Z13.5 Special screening examination for eye and ear disorders
0.688 0.311 0.000
Z13.4 Special screening examination for certain developmental disorders in childhood
0.688 0.311 0.000
Z13.3 Special screening examination for mental and behavioural disorders
0.688 0.311 0.000
Z13.2 Special screening examination for nutritional disorders
0.688 0.311 0.000
K92.9 Disease of digestive system, unspecified
0.688 0.312 0.000
K92.8 Other specified diseases of digestive system
0.688 0.312 0.000
N83.7 Haematoma of broad ligament
0.688 0.312 0.000
N83.6 Haematosalpinx
0.688 0.312 0.000
N83.5 Torsion of ovary, ovarian pedicle and Fallopian tube
0.688 0.312 0.000
N83.4 Prolapse and hernia of ovary and Fallopian tube
0.688 0.312 0.000
N83.3 Acquired atrophy of ovary and Fallopian tube
0.688 0.312 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.687 0.313 0.000
K77 Liver disorders in diseases classified elsewhere
0.686 0.313 0.000
K73 Chronic hepatitis, not elsewhere classified
0.686 0.313 0.000
K71 Toxic liver disease
0.686 0.313 0.000
M75.2 Bicipital tendinitis
0.686 0.314 0.000
I35.1 Aortic (valve) insufficiency
0.686 0.314 0.000
Z98 Other postsurgical states
0.685 0.314 0.000
E14 Unspecified diabetes mellitus
0.685 0.315 0.000
Z36 Antenatal screening
0.685 0.315 0.000
Z01.6 Radiological examination, not elsewhere classified
0.685 0.315 0.000
Chapter VII Diseases of the eye and adnexa
0.684 0.316 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.684 0.316 0.000
I08 Multiple valve diseases
0.684 0.316 0.000
J40-J47 Chronic lower respiratory diseases
0.683 0.317 0.000
M75.4 Impingement syndrome of shoulder
0.682 0.318 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.681 0.319 0.000
I51.6 Cardiovascular disease, unspecified
0.680 0.320 0.000
I51.5 Myocardial degeneration
0.680 0.320 0.000
I51.4 Myocarditis, unspecified
0.680 0.320 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.680 0.320 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.680 0.320 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.680 0.320 0.000
I51.0 Cardiac septal defect, acquired
0.680 0.320 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.680 0.320 0.000
Z13.1 Special screening examination for diabetes mellitus
0.680 0.320 0.000
M10.9 Gout, unspecified
0.679 0.321 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.678 0.322 0.000
Z54 Convalescence
0.677 0.323 0.000
Z52 Donors of organs and tissues
0.677 0.323 0.000
Z49 Care involving dialysis
0.677 0.323 0.000
Z44 Fitting and adjustment of external prosthetic device
0.677 0.323 0.000
K70.3 Alcoholic cirrhosis of liver
0.677 0.323 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.676 0.323 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.676 0.324 0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues
0.676 0.324 0.000
Z80.6 Family history of leukaemia
0.676 0.324 0.000
Z80.5 Family history of malignant neoplasm of urinary tract
0.676 0.324 0.000
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs
0.676 0.324 0.000
K74.5 Biliary cirrhosis, unspecified
0.675 0.325 0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.675 0.325 0.000
E67 Other hyperalimentation
0.674 0.326 0.000
E68 Sequelae of hyperalimentation
0.674 0.326 0.000
E65 Localised adiposity
0.674 0.326 0.000
N60-N64 Disorders of breast
0.674 0.326 0.000
Y83.0 Surgical operation with transplant of whole organ
0.674 0.326 0.000
C15.5 Lower third of oesophagus
0.673 0.327 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.672 0.328 0.000
G60 Hereditary and idiopathic neuropathy
0.671 0.329 0.000
N92.5 Other specified irregular menstruation
0.670 0.330 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.670 0.330 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.670 0.330 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.670 0.330 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.669 0.331 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.669 0.331 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.669 0.331 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.669 0.331 0.000
Z97.4 Presence of external hearing-aid
0.669 0.331 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.669 0.331 0.000
Z45 Adjustment and management of implanted device
0.668 0.332 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.667 0.333 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.667 0.333 0.000
F30-F39 Mood [affective] disorders
0.667 0.333 0.000
Y42.9 Other and unspecified hormone antagonists
0.667 0.333 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.667 0.333 0.000
Y42.4 Oral contraceptives
0.667 0.333 0.000
Y42.2 Antithyroid drugs
0.667 0.333 0.000
Y42.1 Thyroid hormones and substitutes
0.667 0.333 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.667 0.333 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.667 0.333 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.667 0.333 0.000
D69.6 Thrombocytopenia, unspecified
0.667 0.333 0.000
K70.9 Alcoholic liver disease, unspecified
0.666 0.334 0.000
D10-D36 Benign neoplasms
0.666 0.334 0.000
C61 Malignant neoplasm of prostate
0.665 0.335 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.665 0.335 0.000
Y83.9 Surgical procedure, unspecified
0.665 0.335 0.000
Z04.9 Examination and observation for unspecified reason
0.665 0.335 0.000
I31 Other diseases of pericardium
0.663 0.337 0.000
I42 Cardiomyopathy
0.663 0.337 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.663 0.337 0.000
M06.9 Rheumatoid arthritis, unspecified
0.663 0.337 0.000
Z50.8 Care involving use of rehabilitation procedures
0.663 0.337 0.000
E06 Thyroiditis
0.663 0.337 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.663 0.337 0.000
E00 Congenital iodine-deficiency syndrome
0.663 0.337 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.663 0.337 0.000
M72.2 Plantar fascial fibromatosis
0.662 0.338 0.000
O74 Complications of anaesthesia during labour and delivery
0.661 0.338 0.000
O73 Retained placenta and membranes, without haemorrhage
0.661 0.338 0.000
O71 Other obstetric trauma
0.661 0.338 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.661 0.338 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.661 0.338 0.000
O62 Abnormalities of forces of labour
0.661 0.338 0.000
O61 Failed induction of labour
0.661 0.338 0.000
O60 Preterm delivery
0.661 0.338 0.000
N87.9 Dysplasia of cervix uteri, unspecified
0.661 0.339 0.000
N25-N29 Other disorders of kidney and ureter
0.661 0.339 0.000
K35-K38 Diseases of appendix
0.661 0.339 0.000
T33-T35 Frostbite
0.660 0.340 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.660 0.340 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.660 0.340 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.660 0.340 0.000
T00-T07 Injuries involving multiple body regions
0.660 0.340 0.000
S10-S19 Injuries to the neck
0.660 0.340 0.000
Z75 Problems related to medical facilities and other health care
0.660 0.340 0.000
Z22 Carrier of infectious disease
0.660 0.340 0.000
I47 Paroxysmal tachycardia
0.659 0.341 0.000
W10 Fall on and from stairs and steps
0.659 0.341 0.000
I34.0 Mitral (valve) insufficiency
0.658 0.342 0.000
I23 Certain current complications following acute myocardial infarction
0.657 0.343 0.000
Z97.3 Presence of spectacles and contact lenses
0.656 0.344 0.000
Z97.2 Presence of dental prosthetic device (complete)(partial)
0.656 0.344 0.000
Z97.1 Presence of artificial limb (complete)(partial)
0.656 0.344 0.000
N90.7 Vulvar cyst
0.656 0.344 0.000
Y45.0 Opioids and related analgesics
0.655 0.345 0.000
T79-T79 Certain early complications of trauma
0.655 0.345 0.000
N92.0 Excessive and frequent menstruation with regular cycle
0.655 0.345 0.000
M79.6 Pain in limb
0.655 0.345 0.000
M65-M68 Disorders of synovium and tendon
0.655 0.345 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.655 0.345 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.654 0.346 0.000
M14 Arthropathies in other diseases classified elsewhere
0.654 0.346 0.000
M12 Other specific arthropathies
0.654 0.346 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.654 0.346 0.000
M08 Juvenile arthritis
0.654 0.346 0.000
Z09.7 Follow-up examination after combined treatment for other conditions
0.654 0.346 0.000
Z09.4 Follow-up examination after treatment of fracture
0.654 0.346 0.000
Z09.3 Follow-up examination after psychotherapy
0.654 0.346 0.000
Z09.1 Follow-up examination after radiotherapy for other conditions
0.654 0.346 0.000
M75.8 Other shoulder lesions
0.653 0.346 0.000
O45 Premature separation of placenta [abruptio placentae]
0.653 0.347 0.000
O44 Placenta praevia
0.653 0.347 0.000
O41 Other disorders of amniotic fluid and membranes
0.653 0.347 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.653 0.347 0.000
O33 Maternal care for known or suspected disproportion
0.653 0.347 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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