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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs35647108
log Bayes Factor = 53.922
Chromosome 6   position 31,274,449  (GRCh37) Explore rs35647108 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
1.000 0.000 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
1.000 0.000 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
1.000 0.000 0.000
M06 Other rheumatoid arthritis
1.000 0.000 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.999 0.001 0.000
M05 Seropositive rheumatoid arthritis
0.999 0.001 0.000
M05-M14 Inflammatory polyarthropathies
0.999 0.001 0.000
E10.3 With ophthalmic complications
0.998 0.002 0.000
E14 Unspecified diabetes mellitus
0.990 0.010 0.000
E10.1 With ketoacidosis
0.984 0.016 0.000
E11 Non-insulin-dependent diabetes mellitus
0.980 0.020 0.000
E14.9 Without complications
0.978 0.022 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.972 0.028 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.969 0.031 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.962 0.038 0.000
M06.3 Rheumatoid nodule
0.961 0.039 0.000
E10.4 With neurological complications
0.949 0.051 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.922 0.078 0.000
E10.5 With peripheral circulatory complications
0.921 0.079 0.000
E11.5 With peripheral circulatory complications
0.908 0.092 0.000
M06.34 Rheumatoid nodule (Hand)
0.904 0.096 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.904 0.096 0.000
E10.0 With coma
0.900 0.100 0.000
E11.4 With neurological complications
0.888 0.112 0.000
E11.9 Without complications
0.876 0.124 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.869 0.131 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.852 0.148 0.000
E11.0 With coma
0.835 0.165 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.827 0.173 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.823 0.177 0.000
M12 Other specific arthropathies
0.819 0.181 0.000
M10 Gout
0.816 0.183 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.806 0.194 0.000
M14 Arthropathies in other diseases classified elsewhere
0.804 0.196 0.000
E14.6 With other specified complications
0.801 0.199 0.000
E14.8 With unspecified complications
0.800 0.200 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.795 0.205 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.787 0.213 0.000
E14.1 With ketoacidosis
0.784 0.216 0.000
E10.2 With renal complications
0.777 0.223 0.000
E10.8 With unspecified complications
0.776 0.223 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.776 0.224 0.000
C61 Malignant neoplasm of prostate
0.776 0.224 0.000
E13 Other specified diabetes mellitus
0.772 0.227 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.768 0.232 0.000
E10.6 With other specified complications
0.765 0.235 0.000
E14.4 With neurological complications
0.738 0.261 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.738 0.262 0.000
E11.8 With unspecified complications
0.736 0.264 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.729 0.271 0.000
E10.7 With multiple complications
0.717 0.283 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.717 0.283 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.717 0.283 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.717 0.283 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.717 0.283 0.000
M06.8 Other specified rheumatoid arthritis
0.717 0.283 0.000
M06.2 Rheumatoid bursitis
0.717 0.283 0.000
M06.1 Adult-onset Still's disease
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
M05.8 Other seropositive rheumatoid arthritis
0.717 0.283 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.717 0.283 0.000
M05.2 Rheumatoid vasculitis
0.717 0.283 0.000
M05.1 Rheumatoid lung disease
0.717 0.283 0.000
M05.0 Felty's syndrome
0.717 0.283 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.716 0.283 0.000
M08 Juvenile arthritis
0.716 0.283 0.000
E14.7 With multiple complications
0.710 0.290 0.000
E14.5 With peripheral circulatory complications
0.710 0.290 0.000
E14.2 Withrenal complications
0.710 0.290 0.000
E14.0 With coma
0.710 0.290 0.000
M06.4 Inflammatory polyarthropathy
0.705 0.295 0.000
E11.7 With multiple complications
0.703 0.297 0.000
E11.6 With other specified complications
0.702 0.298 0.000
M11 Other crystal arthropathies
0.693 0.306 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.691 0.309 0.000
E16 Other disorders of pancreatic internal secretion
0.690 0.310 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.689 0.311 0.000
M06.38 Rheumatoid nodule (Other)
0.689 0.311 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.689 0.311 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.689 0.311 0.000
M06.33 Rheumatoid nodule (Forearm)
0.689 0.311 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.689 0.311 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.689 0.311 0.000
M10.9 Gout, unspecified
0.684 0.316 0.000
E11.1 With ketoacidosis
0.681 0.319 0.000
E70-E90 Metabolic disorders
0.668 0.332 0.000
E40-E46 Malnutrition
0.667 0.333 0.000
M14.6 Neuropathic arthropathy
0.663 0.337 0.000
E20-E35 Disorders of other endocrine glands
0.657 0.343 0.000
E16.2 Hypoglycaemia, unspecified
0.656 0.344 0.000
M12.3 Palindromic rheumatism
0.654 0.346 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.646 0.354 0.000
M12.2 Villonodular synovitis (pigmented)
0.638 0.362 0.000
M06.0 Seronegative rheumatoid arthritis
0.638 0.362 0.000
E89.3 Postprocedural hypopituitarism
0.617 0.383 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.614 0.385 0.000
E13.9 Without complications
0.610 0.390 0.000
E85 Amyloidosis
0.607 0.393 0.000
E03 Other hypothyroidism
0.058 0.401 0.541
E22 Hyperfunction of pituitary gland
0.593 0.407 0.000
M10.0 Idiopathic gout
0.588 0.412 0.000
M12.8 Other specific arthropathies, not elsewhere classified
0.587 0.412 0.000
M12.5 Traumatic arthropathy
0.587 0.412 0.000
M12.4 Intermittent hydrarthrosis
0.587 0.412 0.000
M12.1 Kaschin-Beck disease
0.587 0.412 0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.587 0.412 0.000
M10.4 Other secondary gout
0.585 0.414 0.000
M10.3 Gout due to impairment of renal function
0.585 0.414 0.000
M10.2 Drug-induced gout
0.585 0.414 0.000
M10.1 Lead-induced gout
0.585 0.414 0.000
M10.99 Gout, unspecified (Site unspecified)
0.583 0.417 0.000
E29 Testicular dysfunction
0.582 0.418 0.000
E50-E64 Other nutritional deficiencies
0.581 0.419 0.000
M14.8 Arthropathies in other specified diseases classified elsewhere
0.576 0.424 0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.576 0.424 0.000
M14.4 Arthropathy in amyloidosis
0.576 0.424 0.000
M14.3 Lipoid dermatoarthritis
0.576 0.424 0.000
M14.2 Diabetic arthropathy
0.576 0.424 0.000
M14.1 Crystal arthropathy in other metabolic disorders
0.576 0.424 0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.576 0.424 0.000
E65-E68 Obesity and other hyperalimentation
0.570 0.430 0.000
E46 Unspecified protein-energy malnutrition
0.568 0.432 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.563 0.436 0.000
E88 Other metabolic disorders
0.563 0.437 0.000
E89.1 Postprocedural hypoinsulinaemia
0.559 0.441 0.000
E13.8 With unspecified complications
0.554 0.446 0.000
E13.7 With multiple complications
0.554 0.446 0.000
E13.6 With other specified complications
0.554 0.446 0.000
E13.5 With peripheral circulatory complications
0.554 0.446 0.000
E13.4 With neurological complications
0.554 0.446 0.000
E13.3 With ophthalmic complications
0.554 0.446 0.000
E13.2 With renal complications
0.554 0.446 0.000
E13.1 With ketoacidosis
0.554 0.446 0.000
E13.0 With coma
0.554 0.446 0.000
E89.2 Postprocedural hypoparathyroidism
0.554 0.446 0.000
M07 Psoriatic and enteropathic arthropathies
0.551 0.449 0.000
E22.0 Acromegaly and pituitary gigantism
0.550 0.450 0.000
E11.3 With ophthalmic complications
0.549 0.451 0.000
E85.4 Organ-limited amyloidosis
0.541 0.459 0.000
E79 Disorders of purine and pyrimidine metabolism
0.539 0.461 0.000
M12.39 Palindromic rheumatism (Site unspecified)
0.536 0.464 0.000
E74 Other disorders of carbohydrate metabolism
0.535 0.465 0.000
E15 Nondiabetic hypoglycaemic coma
0.529 0.471 0.000
E29.1 Testicular hypofunction
0.529 0.471 0.000
E34 Other endocrine disorders
0.528 0.472 0.000
M13 Other arthritis
0.525 0.475 0.000
M06.19 Adult-onset Still's disease (Site unspecified)
0.514 0.486 0.000
M06.18 Adult-onset Still's disease (Other)
0.514 0.486 0.000
M06.17 Adult-onset Still's disease (Ankle and foot)
0.514 0.486 0.000
M06.16 Adult-onset Still's disease (Lower leg)
0.514 0.486 0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.514 0.486 0.000
M06.14 Adult-onset Still's disease (Hand)
0.514 0.486 0.000
M06.13 Adult-onset Still's disease (Forearm)
0.514 0.486 0.000
M06.12 Adult-onset Still's disease (Upper arm)
0.514 0.486 0.000
M06.11 Adult-onset Still's disease (Shoulder region)
0.514 0.486 0.000
M06.10 Adult-onset Still's disease (Multiple sites)
0.514 0.486 0.000
M06.29 Rheumatoid bursitis (Site unspecified)
0.514 0.486 0.000
M06.28 Rheumatoid bursitis (Other)
0.514 0.486 0.000
M06.27 Rheumatoid bursitis (Ankle and foot)
0.514 0.486 0.000
M06.26 Rheumatoid bursitis (Lower leg)
0.514 0.486 0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.514 0.486 0.000
M06.24 Rheumatoid bursitis (Hand)
0.514 0.486 0.000
M06.23 Rheumatoid bursitis (Forearm)
0.514 0.486 0.000
M06.22 Rheumatoid bursitis (Upper arm)
0.514 0.486 0.000
M06.21 Rheumatoid bursitis (Shoulder region)
0.514 0.486 0.000
M06.20 Rheumatoid bursitis (Multiple sites)
0.514 0.486 0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.514 0.486 0.000
M06.88 Other specified rheumatoid arthritis (Other)
0.514 0.486 0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.514 0.486 0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.514 0.486 0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.514 0.486 0.000
M06.84 Other specified rheumatoid arthritis (Hand)
0.514 0.486 0.000
M06.83 Other specified rheumatoid arthritis (Forearm)
0.514 0.486 0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.514 0.486 0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.514 0.486 0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.514 0.486 0.000
M05.09 Felty's syndrome (Site unspecified)
0.514 0.486 0.000
M05.08 Felty's syndrome (Other)
0.514 0.486 0.000
M05.07 Felty's syndrome (Ankle and foot)
0.514 0.486 0.000
M05.06 Felty's syndrome (Lower leg)
0.514 0.486 0.000
M05.05 Felty's syndrome (Pelvic region and thigh)
0.514 0.486 0.000
M05.04 Felty's syndrome (Hand)
0.514 0.486 0.000
M05.03 Felty's syndrome (Forearm)
0.514 0.486 0.000
M05.02 Felty's syndrome (Upper arm)
0.514 0.486 0.000
M05.01 Felty's syndrome (Shoulder region)
0.514 0.486 0.000
M05.00 Felty's syndrome (Multiple sites)
0.514 0.486 0.000
M05.19 Rheumatoid lung disease (Site unspecified)
0.514 0.486 0.000
M05.18 Rheumatoid lung disease (Other)
0.514 0.486 0.000
M05.17 Rheumatoid lung disease (Ankle and foot)
0.514 0.486 0.000
M05.16 Rheumatoid lung disease (Lower leg)
0.514 0.486 0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.514 0.486 0.000
M05.14 Rheumatoid lung disease (Hand)
0.514 0.486 0.000
M05.13 Rheumatoid lung disease (Forearm)
0.514 0.486 0.000
M05.12 Rheumatoid lung disease (Upper arm)
0.514 0.486 0.000
M05.11 Rheumatoid lung disease (Shoulder region)
0.514 0.486 0.000
M05.10 Rheumatoid lung disease (Multiple sites)
0.514 0.486 0.000
M05.29 Rheumatoid vasculitis (Site unspecified)
0.514 0.486 0.000
M05.28 Rheumatoid vasculitis (Other)
0.514 0.486 0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.514 0.486 0.000
M05.26 Rheumatoid vasculitis (Lower leg)
0.514 0.486 0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)
0.514 0.486 0.000
M05.24 Rheumatoid vasculitis (Hand)
0.514 0.486 0.000
M05.23 Rheumatoid vasculitis (Forearm)
0.514 0.486 0.000
M05.22 Rheumatoid vasculitis (Upper arm)
0.514 0.486 0.000
M05.21 Rheumatoid vasculitis (Shoulder region)
0.514 0.486 0.000
M05.20 Rheumatoid vasculitis (Multiple sites)
0.514 0.486 0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.514 0.486 0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.514 0.486 0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.514 0.486 0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.514 0.486 0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.514 0.486 0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.514 0.486 0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.514 0.486 0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.514 0.486 0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)
0.514 0.486 0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)
0.514 0.486 0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.514 0.486 0.000
M05.88 Other seropositive rheumatoid arthritis (Other)
0.514 0.486 0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.514 0.486 0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.514 0.486 0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.514 0.486 0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.514 0.486 0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.514 0.486 0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.514 0.486 0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.514 0.486 0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.514 0.486 0.000
E12.9 Without complications
0.514 0.486 0.000
E12.8 With unspecified complications
0.514 0.486 0.000
E12.7 With multiple complications
0.514 0.486 0.000
E12.6 With other specified complications
0.514 0.486 0.000
E12.5 With peripheral circulatory complications
0.514 0.486 0.000
E12.4 With neurological complications
0.514 0.486 0.000
E12.3 With ophthalmic complications
0.514 0.486 0.000
E12.2 With renal complications
0.514 0.486 0.000
E12.1 With ketoacidosis
0.514 0.486 0.000
E12.0 With coma
0.514 0.486 0.000
M08.9 Juvenile arthritis, unspecified
0.514 0.486 0.000
M08.8 Other juvenile arthritis
0.514 0.486 0.000
M08.4 Pauciarticular juvenile arthritis
0.514 0.486 0.000
M08.3 Juvenile polyarthritis (seronegative)
0.514 0.486 0.000
M08.2 Juvenile arthritis with systemic onset
0.514 0.486 0.000
M08.1 Juvenile ankylosing spondylitis
0.514 0.486 0.000
M08.0 Juvenile rheumatoid arthritis
0.514 0.486 0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.514 0.486 0.000
M09.2 Juvenile arthritis in ulcerative colitis
0.514 0.486 0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.514 0.486 0.000
M09.0 Juvenile arthritis in psoriasis
0.514 0.486 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.509 0.491 0.000
E16.1 Other hypoglycaemia
0.508 0.491 0.000
M12.24 Villonodular synovitis (pigmented) (Hand)
0.508 0.492 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.505 0.494 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.505 0.494 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.505 0.494 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.505 0.494 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.505 0.494 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.505 0.494 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.505 0.494 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.505 0.494 0.000
E85.9 Amyloidosis, unspecified
0.503 0.497 0.000
M11.9 Crystal arthropathy, unspecified
0.497 0.503 0.000
M11.8 Other specified crystal arthropathies
0.497 0.503 0.000
M11.1 Familial chondrocalcinosis
0.497 0.503 0.000
M11.0 Hydroxyapatite deposition disease
0.497 0.503 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.497 0.503 0.000
E22.1 Hyperprolactinaemia
0.497 0.503 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.494 0.505 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.494 0.505 0.000
E16.4 Abnormal secretion of gastrin
0.494 0.505 0.000
E16.3 Increased secretion of glucagon
0.494 0.505 0.000
M10.98 Gout, unspecified (Other)
0.490 0.509 0.000
M10.95 Gout, unspecified (Pelvic region and thigh)
0.490 0.509 0.000
M10.92 Gout, unspecified (Upper arm)
0.490 0.509 0.000
M10.91 Gout, unspecified (Shoulder region)
0.490 0.509 0.000
M10.96 Gout, unspecified (Lower leg)
0.484 0.516 0.000
E84 Cystic fibrosis
0.479 0.521 0.000
E77 Disorders of glycoprotein metabolism
0.479 0.521 0.000
E76 Disorders of glycosaminoglycan metabolism
0.479 0.521 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.479 0.521 0.000
E72 Other disorders of amino-acid metabolism
0.479 0.521 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.479 0.521 0.000
E70 Disorders of aromatic amino-acid metabolism
0.479 0.521 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.479 0.521 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.478 0.521 0.000
E45 Retarded development following protein-energy malnutrition
0.478 0.521 0.000
E43 Unspecified severe protein-energy malnutrition
0.478 0.521 0.000
E42 Marasmic kwashiorkor
0.478 0.521 0.000
E41 Nutritional marasmus
0.478 0.521 0.000
E40 Kwashiorkor
0.478 0.521 0.000
E14.3 With ophthalmic complications
0.477 0.523 0.000
M11.2 Other chondrocalcinosis
0.474 0.526 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.473 0.527 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.471 0.529 0.000
E32 Diseases of thymus
0.471 0.529 0.000
E31 Polyglandular dysfunction
0.471 0.529 0.000
E30 Disorders of puberty, not elsewhere classified
0.471 0.529 0.000
E25 Adrenogenital disorders
0.471 0.529 0.000
M12.38 Palindromic rheumatism (Other)
0.469 0.531 0.000
M12.37 Palindromic rheumatism (Ankle and foot)
0.469 0.531 0.000
M12.36 Palindromic rheumatism (Lower leg)
0.469 0.531 0.000
M12.35 Palindromic rheumatism (Pelvic region and thigh)
0.469 0.531 0.000
M12.34 Palindromic rheumatism (Hand)
0.469 0.531 0.000
M12.33 Palindromic rheumatism (Forearm)
0.469 0.531 0.000
M12.32 Palindromic rheumatism (Upper arm)
0.469 0.531 0.000
M12.31 Palindromic rheumatism (Shoulder region)
0.469 0.531 0.000
M12.30 Palindromic rheumatism (Multiple sites)
0.469 0.531 0.000
E61 Deficiency of other nutrient elements
0.468 0.532 0.000
E20 Hypoparathyroidism
0.467 0.533 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.463 0.537 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.463 0.537 0.000
E89.5 Postprocedural testicular hypofunction
0.463 0.537 0.000
E89.4 Postprocedural ovarian failure
0.463 0.537 0.000
E26 Hyperaldosteronism
0.459 0.541 0.000
E03.8 Other specified hypothyroidism
0.032 0.541 0.427
M12.29 Villonodular synovitis (pigmented) (Site unspecified)
0.458 0.542 0.000
M12.28 Villonodular synovitis (pigmented) (Other)
0.458 0.542 0.000
M12.27 Villonodular synovitis (pigmented) (Ankle and foot)
0.458 0.542 0.000
M12.26 Villonodular synovitis (pigmented) (Lower leg)
0.458 0.542 0.000
M12.25 Villonodular synovitis (pigmented) (Pelvic region and thigh)
0.458 0.542 0.000
M12.23 Villonodular synovitis (pigmented) (Forearm)
0.458 0.542 0.000
M12.22 Villonodular synovitis (pigmented) (Upper arm)
0.458 0.542 0.000
M12.21 Villonodular synovitis (pigmented) (Shoulder region)
0.458 0.542 0.000
M12.20 Villonodular synovitis (pigmented) (Multiple sites)
0.458 0.542 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.457 0.543 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.457 0.543 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.457 0.543 0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.457 0.543 0.000
M06.04 Seronegative rheumatoid arthritis (Hand)
0.457 0.543 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.457 0.543 0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.457 0.543 0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.457 0.543 0.000
M10.93 Gout, unspecified (Forearm)
0.455 0.545 0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.447 0.553 0.000
M10.94 Gout, unspecified (Hand)
0.447 0.553 0.000
E24 Cushing's syndrome
0.443 0.557 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.440 0.560 0.000
E11.2 With renal complications
0.440 0.560 0.000
M10.09 Idiopathic gout (Site unspecified)
0.438 0.562 0.000
E85.8 Other amyloidosis
0.435 0.565 0.000
E85.2 Heredofamilial amyloidosis, unspecified
0.435 0.565 0.000
E85.1 Neuropathic heredofamilial amyloidosis
0.435 0.565 0.000
E85.0 Nonneuropathic heredofamilial amyloidosis
0.435 0.565 0.000
E86 Volume depletion
0.433 0.567 0.000
E55 Vitamin D deficiency
0.430 0.570 0.000
E03.5 Myxoedema coma
0.042 0.570 0.388
E03.4 Atrophy of thyroid (acquired)
0.042 0.570 0.388
E03.3 Postinfectious hypothyroidism
0.042 0.570 0.388
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.042 0.570 0.388
E03.1 Congenital hypothyroidism without goitre
0.042 0.570 0.388
E03.0 Congenital hypothyroidism with diffuse goitre
0.042 0.570 0.388
E65 Localised adiposity
0.428 0.572 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.425 0.575 0.000
E22.8 Other hyperfunction of pituitary gland
0.425 0.575 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.424 0.576 0.000
E73 Lactose intolerance
0.422 0.578 0.000
M10.08 Idiopathic gout (Other)
0.422 0.578 0.000
M10.06 Idiopathic gout (Lower leg)
0.422 0.578 0.000
M10.05 Idiopathic gout (Pelvic region and thigh)
0.422 0.578 0.000
M10.04 Idiopathic gout (Hand)
0.422 0.578 0.000
M10.03 Idiopathic gout (Forearm)
0.422 0.578 0.000
M10.02 Idiopathic gout (Upper arm)
0.422 0.578 0.000
M10.01 Idiopathic gout (Shoulder region)
0.422 0.578 0.000
M10.00 Idiopathic gout (Multiple sites)
0.422 0.578 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.421 0.578 0.000
M12.09 Chronic postrheumatic arthropathy [Jaccoud] (Site unspecified)
0.421 0.579 0.000
M12.08 Chronic postrheumatic arthropathy [Jaccoud] (Other)
0.421 0.579 0.000
M12.07 Chronic postrheumatic arthropathy [Jaccoud] (Ankle and foot)
0.421 0.579 0.000
M12.06 Chronic postrheumatic arthropathy [Jaccoud] (Lower leg)
0.421 0.579 0.000
M12.05 Chronic postrheumatic arthropathy [Jaccoud] (Pelvic region and thigh)
0.421 0.579 0.000
M12.04 Chronic postrheumatic arthropathy [Jaccoud] (Hand)
0.421 0.579 0.000
M12.03 Chronic postrheumatic arthropathy [Jaccoud] (Forearm)
0.421 0.579 0.000
M12.02 Chronic postrheumatic arthropathy [Jaccoud] (Upper arm)
0.421 0.579 0.000
M12.01 Chronic postrheumatic arthropathy [Jaccoud] (Shoulder region)
0.421 0.579 0.000
M12.00 Chronic postrheumatic arthropathy [Jaccoud] (Multiple sites)
0.421 0.579 0.000
M12.19 Kaschin-Beck disease (Site unspecified)
0.421 0.579 0.000
M12.18 Kaschin-Beck disease (Other)
0.421 0.579 0.000
M12.17 Kaschin-Beck disease (Ankle and foot)
0.421 0.579 0.000
M12.16 Kaschin-Beck disease (Lower leg)
0.421 0.579 0.000
M12.15 Kaschin-Beck disease (Pelvic region and thigh)
0.421 0.579 0.000
M12.14 Kaschin-Beck disease (Hand)
0.421 0.579 0.000
M12.13 Kaschin-Beck disease (Forearm)
0.421 0.579 0.000
M12.12 Kaschin-Beck disease (Upper arm)
0.421 0.579 0.000
M12.11 Kaschin-Beck disease (Shoulder region)
0.421 0.579 0.000
M12.10 Kaschin-Beck disease (Multiple sites)
0.421 0.579 0.000
M12.49 Intermittent hydrarthrosis (Site unspecified)
0.421 0.579 0.000
M12.48 Intermittent hydrarthrosis (Other)
0.421 0.579 0.000
M12.47 Intermittent hydrarthrosis (Ankle and foot)
0.421 0.579 0.000
M12.46 Intermittent hydrarthrosis (Lower leg)
0.421 0.579 0.000
M12.45 Intermittent hydrarthrosis (Pelvic region and thigh)
0.421 0.579 0.000
M12.44 Intermittent hydrarthrosis (Hand)
0.421 0.579 0.000
M12.43 Intermittent hydrarthrosis (Forearm)
0.421 0.579 0.000
M12.42 Intermittent hydrarthrosis (Upper arm)
0.421 0.579 0.000
M12.41 Intermittent hydrarthrosis (Shoulder region)
0.421 0.579 0.000
M12.40 Intermittent hydrarthrosis (Multiple sites)
0.421 0.579 0.000
M12.59 Traumatic arthropathy (Site unspecified)
0.421 0.579 0.000
M12.58 Traumatic arthropathy (Other)
0.421 0.579 0.000
M12.57 Traumatic arthropathy (Ankle and foot)
0.421 0.579 0.000
M12.56 Traumatic arthropathy (Lower leg)
0.421 0.579 0.000
M12.55 Traumatic arthropathy (Pelvic region and thigh)
0.421 0.579 0.000
M12.54 Traumatic arthropathy (Hand)
0.421 0.579 0.000
M12.53 Traumatic arthropathy (Forearm)
0.421 0.579 0.000
M12.52 Traumatic arthropathy (Upper arm)
0.421 0.579 0.000
M12.51 Traumatic arthropathy (Shoulder region)
0.421 0.579 0.000
M12.50 Traumatic arthropathy (Multiple sites)
0.421 0.579 0.000
M12.89 Other specific arthropathies, not elsewhere classified (Site unspecified)
0.421 0.579 0.000
M12.88 Other specific arthropathies, not elsewhere classified (Other)
0.421 0.579 0.000
M12.87 Other specific arthropathies, not elsewhere classified (Ankle and foot)
0.421 0.579 0.000
M12.86 Other specific arthropathies, not elsewhere classified (Lower leg)
0.421 0.579 0.000
M12.85 Other specific arthropathies, not elsewhere classified (Pelvic region and thigh)
0.421 0.579 0.000
M12.84 Other specific arthropathies, not elsewhere classified (Hand)
0.421 0.579 0.000
M12.83 Other specific arthropathies, not elsewhere classified (Forearm)
0.421 0.579 0.000
M12.82 Other specific arthropathies, not elsewhere classified (Upper arm)
0.421 0.579 0.000
M12.81 Other specific arthropathies, not elsewhere classified (Shoulder region)
0.421 0.579 0.000
M12.80 Other specific arthropathies, not elsewhere classified (Multiple sites)
0.421 0.579 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.421 0.579 0.000
E34.9 Endocrine disorder, unspecified
0.421 0.579 0.000
M10.19 Lead-induced gout (Site unspecified)
0.420 0.580 0.000
M10.18 Lead-induced gout (Other)
0.420 0.580 0.000
M10.17 Lead-induced gout (Ankle and foot)
0.420 0.580 0.000
M10.16 Lead-induced gout (Lower leg)
0.420 0.580 0.000
M10.15 Lead-induced gout (Pelvic region and thigh)
0.420 0.580 0.000
M10.14 Lead-induced gout (Hand)
0.420 0.580 0.000
M10.13 Lead-induced gout (Forearm)
0.420 0.580 0.000
M10.12 Lead-induced gout (Upper arm)
0.420 0.580 0.000
M10.11 Lead-induced gout (Shoulder region)
0.420 0.580 0.000
M10.10 Lead-induced gout (Multiple sites)
0.420 0.580 0.000
M10.29 Drug-induced gout (Site unspecified)
0.420 0.580 0.000
M10.28 Drug-induced gout (Other)
0.420 0.580 0.000
M10.27 Drug-induced gout (Ankle and foot)
0.420 0.580 0.000
M10.26 Drug-induced gout (Lower leg)
0.420 0.580 0.000
M10.25 Drug-induced gout (Pelvic region and thigh)
0.420 0.580 0.000
M10.24 Drug-induced gout (Hand)
0.420 0.580 0.000
M10.23 Drug-induced gout (Forearm)
0.420 0.580 0.000
M10.22 Drug-induced gout (Upper arm)
0.420 0.580 0.000
M10.21 Drug-induced gout (Shoulder region)
0.420 0.580 0.000
M10.20 Drug-induced gout (Multiple sites)
0.420 0.580 0.000
M10.39 Gout due to impairment of renal function (Site unspecified)
0.420 0.580 0.000
M10.38 Gout due to impairment of renal function (Other)
0.420 0.580 0.000
M10.37 Gout due to impairment of renal function (Ankle and foot)
0.420 0.580 0.000
M10.36 Gout due to impairment of renal function (Lower leg)
0.420 0.580 0.000
M10.35 Gout due to impairment of renal function (Pelvic region and thigh)
0.420 0.580 0.000
M10.34 Gout due to impairment of renal function (Hand)
0.420 0.580 0.000
M10.33 Gout due to impairment of renal function (Forearm)
0.420 0.580 0.000
M10.32 Gout due to impairment of renal function (Upper arm)
0.420 0.580 0.000
M10.31 Gout due to impairment of renal function (Shoulder region)
0.420 0.580 0.000
M10.30 Gout due to impairment of renal function (Multiple sites)
0.420 0.580 0.000
M10.49 Other secondary gout (Site unspecified)
0.420 0.580 0.000
M10.48 Other secondary gout (Other)
0.420 0.580 0.000
M10.47 Other secondary gout (Ankle and foot)
0.420 0.580 0.000
M10.46 Other secondary gout (Lower leg)
0.420 0.580 0.000
M10.45 Other secondary gout (Pelvic region and thigh)
0.420 0.580 0.000
M10.44 Other secondary gout (Hand)
0.420 0.580 0.000
M10.43 Other secondary gout (Forearm)
0.420 0.580 0.000
M10.42 Other secondary gout (Upper arm)
0.420 0.580 0.000
M10.41 Other secondary gout (Shoulder region)
0.420 0.580 0.000
M10.40 Other secondary gout (Multiple sites)
0.420 0.580 0.000
E85.3 Secondary systemic amyloidosis
0.419 0.581 0.000
E88.1 Lipodystrophy, not elsewhere classified
0.419 0.581 0.000
E29.9 Testicular dysfunction, unspecified
0.417 0.583 0.000
E29.8 Other testicular dysfunction
0.417 0.583 0.000
E29.0 Testicular hyperfunction
0.417 0.583 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.417 0.583 0.000
E63 Other nutritional deficiencies
0.417 0.583 0.000
E56 Other vitamin deficiencies
0.417 0.583 0.000
E51 Thiamine deficiency
0.417 0.583 0.000
E50 Vitamin A deficiency
0.417 0.583 0.000
E60 Dietary zinc deficiency
0.417 0.583 0.000
E59 Dietary selenium deficiency
0.417 0.583 0.000
E58 Dietary calcium deficiency
0.417 0.583 0.000
E54 Ascorbic acid deficiency
0.417 0.583 0.000
E52 Niacin deficiency [pellagra]
0.417 0.583 0.000
M13.1 Monoarthritis, not elsewhere classified
0.415 0.584 0.000
E34.0 Carcinoid syndrome
0.415 0.585 0.000
M13.8 Other specified arthritis
0.409 0.591 0.000
E67 Other hyperalimentation
0.408 0.591 0.000
E68 Sequelae of hyperalimentation
0.408 0.591 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.407 0.592 0.000
M10.07 Idiopathic gout (Ankle and foot)
0.407 0.593 0.000
E88.9 Metabolic disorder, unspecified
0.404 0.596 0.000
E88.8 Other specified metabolic disorders
0.404 0.596 0.000
E88.3 Tumour lysis syndrome
0.404 0.596 0.000
E61.1 Iron deficiency
0.395 0.604 0.000
M07.6 Other enteropathic arthropathies
0.395 0.605 0.000
M07.5 Arthropathy in ulcerative colitis
0.395 0.605 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.395 0.605 0.000
M07.2 Psoriatic spondylitis
0.395 0.605 0.000
M07.1 Arthritis mutilans
0.395 0.605 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.395 0.605 0.000
E27 Other disorders of adrenal gland
0.393 0.607 0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.387 0.613 0.000
E79.8 Other disorders of purine and pyrimidine metabolism
0.387 0.613 0.000
E79.1 Lesch-Nyhan syndrome
0.387 0.613 0.000
E74.9 Disorder of carbohydrate metabolism, unspecified
0.384 0.616 0.000
E74.8 Other specified disorders of carbohydrate metabolism
0.384 0.616 0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.384 0.616 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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