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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant cluster associations

Hospitalization Episode Statistics (HES)

Cluster X0209
log Bayes Factor = 214.798
contains 8 variants:
rs77774752
lBF = 14.216
Chr 2 : 56,960,157
rs114028985
lBF = 29.334
Chr 2 : 104,957,878
rs111724274
lBF = 36.413
Chr 2 : 200,713,124
rs295130
lBF = 24.026
Chr 2 : 201,229,984
rs115302848
lBF = 9.638
Chr 2 : 210,941,688
rs115023769
lBF = 14.106
Chr 3 : 153,241,084
rs11134797
lBF = 12.674
Chr 5 : 172,860,596
rs74457967
lBF = 15.835
Chr20 : 826,127
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Z03.4 Observation for suspected myocardial infarction
1.000 0.000 0.000
Z51.2 Other chemotherapy
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
1.000 0.000 0.000
A41 Other septicaemia
1.000 0.000 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
1.000 0.000 0.000
M06 Other rheumatoid arthritis
1.000 0.000 0.000
N18 Chronic renal failure
1.000 0.000 0.000
Z51 Other medical care
1.000 0.000 0.000
A30-A49 Other bacterial diseases
1.000 0.000 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
H30-H36 Disorders of choroid and retina
1.000 0.000 0.000
H53-H54 Visual disturbances and blindness
1.000 0.000 0.000
I95-I99 Other and unspecified disorders of the circulatory system
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
1.000 0.000 0.000
M80-M85 Disorders of bone density and structure
1.000 0.000 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
1.000 0.000 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
1.000 0.000 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E11 Non-insulin-dependent diabetes mellitus
1.000 0.000 0.000
F30-F39 Mood [affective] disorders
1.000 0.000 0.000
M70-M79 Other soft tissue disorders
1.000 0.000 0.000
Chapter VIII Diseases of the ear and mastoid process
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
I95 Hypotension
1.000 0.000 0.000
M54 Dorsalgia
1.000 0.000 0.000
Z49 Care involving dialysis
1.000 0.000 0.000
F31 Bipolar affective disorder
1.000 0.000 0.000
E70-E90 Metabolic disorders
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Z51.3 Blood transfusion without reported diagnosis
1.000 0.000 0.000
M10.9 Gout, unspecified
1.000 0.000 0.000
E87.2 Acidosis
1.000 0.000 0.000
I95.9 Hypotension, unspecified
1.000 0.000 0.000
N17-N19 Renal failure
1.000 0.000 0.000
S40-S49 Injuries to the shoulder and upper arm
1.000 0.000 0.000
D69 Purpura and other haemorrhagic conditions
1.000 0.000 0.000
M10 Gout
1.000 0.000 0.000
M79 Other soft tissue disorders, not elsewhere classified
1.000 0.000 0.000
M81 Osteoporosis without pathological fracture
1.000 0.000 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
M81.9 Osteoporosis, unspecified
1.000 0.000 0.000
D60-D64 Aplastic and other anaemias
1.000 0.000 0.000
D70 Agranulocytosis
1.000 0.000 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
1.000 0.000 0.000
Q60-Q64 Congenital malformations of the urinary system
1.000 0.000 0.000
D70-D77 Other diseases of blood and blood-forming organs
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Z99.2 Dependence on renal dialysis
1.000 0.000 0.000
Q61 Cystic kidney disease
1.000 0.000 0.000
M50-M54 Other dorsopathies
1.000 0.000 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
1.000 0.000 0.000
H35 Other retinal disorders
1.000 0.000 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
1.000 0.000 0.000
N18.9 Chronic renal failure, unspecified
1.000 0.000 0.000
H53 Visual disturbances
1.000 0.000 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
1.000 0.000 0.000
Z94 Transplanted organ and tissue status
1.000 0.000 0.000
B35-B49 Mycoses
1.000 0.000 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
1.000 0.000 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
1.000 0.000 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
K50-K52 Noninfective enteritis and colitis
0.999 0.001 0.000
S90-S99 Injuries to the ankle and foot
0.999 0.001 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.999 0.001 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.999 0.001 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.999 0.001 0.000
K52 Other non-infective gastro-enteritis and colitis
0.999 0.001 0.000
K55-K64 Other diseases of intestines
0.999 0.001 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.999 0.001 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.999 0.001 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.999 0.001 0.000
H36 Retinal disorders in diseases classified elsewhere
0.999 0.001 0.000
S10-S19 Injuries to the neck
0.998 0.002 0.000
M84 Disorders of continuity of bone
0.998 0.002 0.000
W00-W19 Falls
0.998 0.002 0.000
H65-H75 Diseases of middle ear and mastoid
0.998 0.002 0.000
H54 Blindness and low vision
0.998 0.002 0.000
N00-N08 Glomerular diseases
0.998 0.002 0.000
I12.0 Hypertensive renal disease with renal failure
0.998 0.002 0.000
K70-K77 Diseases of liver
0.998 0.002 0.000
A41.9 Septicaemia, unspecified
0.998 0.002 0.000
G90-G99 Other disorders of the nervous system
0.998 0.002 0.000
C34 Malignant neoplasm of bronchus and lung
0.998 0.002 0.000
N18.5 Chronic kidney disease, stage 5
0.998 0.002 0.000
M86-M90 Other osteopathies
0.998 0.002 0.000
D68 Other coagulation defects
0.998 0.002 0.000
K55 Vascular disorders of intestine
0.998 0.002 0.000
S00-S09 Injuries to the head
0.998 0.002 0.000
S50-S59 Injuries to the elbow and forearm
0.998 0.002 0.000
H36.0 Diabetic retinopathy
0.998 0.002 0.000
I10-I15 Hypertensive diseases
0.998 0.002 0.000
Z49.1 Extracorporeal dialysis
0.998 0.002 0.000
H60-H62 Diseases of external ear
0.998 0.002 0.000
N18.0 End-stage renal disease
0.997 0.003 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.997 0.003 0.000
I12 Hypertensive renal disease
0.997 0.003 0.000
Y40 Systemic antibiotics
0.997 0.003 0.000
F31.9 Bipolar affective disorder, unspecified
0.997 0.003 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.997 0.003 0.000
Z83 Family history of other specific disorders
0.997 0.003 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.997 0.003 0.000
E87.6 Hypokalaemia
0.997 0.003 0.000
H35.8 Other specified retinal disorders
0.997 0.003 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.997 0.003 0.000
I05-I09 Chronic rheumatic heart diseases
0.997 0.003 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.997 0.003 0.000
K58 Irritable bowel syndrome
0.997 0.003 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.997 0.003 0.000
Q61.2 Polycystic kidney, adult type
0.996 0.004 0.000
R29.6 Tendency to fall, not elsewhere classified
0.996 0.004 0.000
M24 Other specific joint derangements
0.996 0.004 0.000
W20-W49 Exposure to inanimate mechanical forces
0.996 0.004 0.000
D69.6 Thrombocytopenia, unspecified
0.996 0.004 0.000
Q50-Q56 Congenital malformations of genital organs
0.996 0.004 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.996 0.004 0.000
M45-M49 Spondylopathies
0.995 0.005 0.000
H74 Other disorders of middle ear and mastoid
0.995 0.005 0.000
C34.1 Upper lobe, bronchus or lung
0.995 0.005 0.000
I08 Multiple valve diseases
0.995 0.005 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.995 0.005 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.995 0.005 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.995 0.005 0.000
Z94.0 Kidney transplant status
0.995 0.005 0.000
D64 Other anaemias
0.994 0.006 0.000
Z83.5 Family history of eye and ear disorders
0.994 0.006 0.000
K55.9 Vascular disorder of intestine, unspecified
0.994 0.006 0.000
R25 Abnormal involuntary movements
0.994 0.006 0.000
E11.3 With ophthalmic complications
0.993 0.007 0.000
Q61.3 Polycystic kidney, unspecified
0.993 0.007 0.000
M21 Other acquired deformities of limbs
0.993 0.007 0.000
E11.9 Without complications
0.993 0.007 0.000
H53.2 Diplopia
0.993 0.007 0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.992 0.008 0.000
S42 Fracture of shoulder and upper arm
0.992 0.008 0.000
M10.99 Gout, unspecified (Site unspecified)
0.992 0.008 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.992 0.008 0.000
K58.9 Irritable bowel syndrome without diarrhoea
0.992 0.008 0.000
Z52 Donors of organs and tissues
0.991 0.009 0.000
K70 Alcoholic liver disease
0.991 0.009 0.000
Chapter X Diseases of the respiratory system
0.989 0.011 0.000
B37 Candidiasis
0.989 0.011 0.000
E11.4 With neurological complications
0.989 0.011 0.000
H54.4 Blindness, one eye
0.988 0.012 0.000
D68.9 Coagulation defect, unspecified
0.988 0.012 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.988 0.012 0.000
Y84.8 Other medical procedures
0.988 0.012 0.000
D61 Other aplastic anaemias
0.988 0.012 0.000
E10 Insulin-dependent diabetes mellitus
0.988 0.012 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.988 0.012 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.988 0.012 0.000
Z89 Acquired absence of limb
0.987 0.013 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.987 0.013 0.000
H53.9 Visual disturbance, unspecified
0.987 0.013 0.000
S90 Superficial injury of ankle and foot
0.986 0.014 0.000
D64.9 Anaemia, unspecified
0.986 0.014 0.000
E87.7 Fluid overload
0.986 0.014 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.986 0.014 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.985 0.015 0.000
M24.2 Disorder of ligament
0.985 0.015 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.985 0.015 0.000
L20-L30 Dermatitis and eczema
0.984 0.016 0.000
T93 Sequelae of injuries of lower limb
0.984 0.016 0.000
S80-S89 Injuries to the knee and lower leg
0.984 0.016 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.984 0.016 0.000
N76 Other inflammation of vagina and vulva
0.984 0.016 0.000
Y42.7 Androgens and anabolic congeners
0.983 0.017 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.983 0.017 0.000
S12 Fracture of neck
0.983 0.017 0.000
Y84.1 Kidney dialysis
0.983 0.017 0.000
S50 Superficial injury of forearm
0.982 0.018 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.981 0.019 0.000
M54.5 Low back pain
0.980 0.020 0.000
C92 Myeloid leukaemia
0.980 0.020 0.000
B44 Aspergillosis
0.980 0.020 0.000
I85 Oesophageal varices
0.980 0.020 0.000
D61.9 Aplastic anaemia, unspecified
0.979 0.021 0.000
K52.0 Gastro-enteritis and colitis due to radiation
0.979 0.021 0.000
Z52.4 Kidney donor
0.979 0.021 0.000
N25-N29 Other disorders of kidney and ureter
0.979 0.021 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.978 0.022 0.000
H61 Other disorders of external ear
0.977 0.023 0.000
W22 Striking against or struck by other objects
0.977 0.023 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.977 0.023 0.000
M54.2 Cervicalgia
0.977 0.023 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.977 0.023 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.976 0.024 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.976 0.024 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.976 0.024 0.000
J00-J06 Acute upper respiratory infections
0.976 0.024 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.976 0.024 0.000
Z49.0 Preparatory care for dialysis
0.975 0.025 0.000
M89 Other disorders of bone
0.975 0.025 0.000
H55-H59 Other disorders of eye and adnexa
0.975 0.025 0.000
G62 Other polyneuropathies
0.975 0.025 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.975 0.025 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.975 0.025 0.000
M54.9 Dorsalgia, unspecified
0.975 0.025 0.000
S89 Other and unspecified injuries of lower leg
0.974 0.026 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.974 0.026 0.000
K55.0 Acute vascular disorders of intestine
0.973 0.027 0.000
H60 Otitis externa
0.973 0.027 0.000
S41 Open wound of shoulder and upper arm
0.973 0.027 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.972 0.028 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.972 0.028 0.000
Y43 Primarily systemic agents
0.972 0.028 0.000
A49 Bacterial infection of unspecified site
0.971 0.029 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.971 0.029 0.000
S02 Fracture of skull and facial bones
0.971 0.029 0.000
K76 Other diseases of liver
0.970 0.030 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.970 0.030 0.000
Z48 Other surgical follow-up care
0.970 0.030 0.000
Z94.8 Other transplanted organ and tissue status
0.970 0.030 0.000
A49.8 Other bacterial infections of unspecified site
0.969 0.031 0.000
R82 Other abnormal findings in urine
0.969 0.031 0.000
Z49.2 Other dialysis
0.969 0.031 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.969 0.031 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.969 0.031 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.968 0.032 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.968 0.032 0.000
S89.9 Unspecified injury of lower leg
0.968 0.032 0.000
S90.9 Superficial injury of ankle and foot, unspecified
0.968 0.032 0.000
M65-M68 Disorders of synovium and tendon
0.967 0.033 0.000
M47 Spondylosis
0.967 0.033 0.000
J06.9 Acute upper respiratory infection, unspecified
0.967 0.033 0.000
F30 Manic episode
0.966 0.034 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.966 0.034 0.000
M10.96 Gout, unspecified (Lower leg)
0.965 0.035 0.000
M06.3 Rheumatoid nodule
0.965 0.035 0.000
H35.7 Separation of retinal layers
0.964 0.036 0.000
H74.8 Other specified disorders of middle ear and mastoid
0.964 0.036 0.000
B44.1 Other pulmonary aspergillosis
0.963 0.037 0.000
M71 Other bursopathies
0.963 0.037 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.963 0.037 0.000
S50.9 Superficial injury of forearm, unspecified
0.962 0.038 0.000
J09-J18 Influenza and pneumonia
0.962 0.038 0.000
Q50.4 Embryonic cyst of Fallopian tube
0.962 0.038 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.962 0.038 0.000
N04 Nephrotic syndrome
0.962 0.038 0.000
R25.3 Fasciculation
0.962 0.038 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.961 0.039 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.961 0.039 0.000
C92.0 Acute myeloid leukaemia
0.959 0.041 0.000
Z51.9 Medical care, unspecified
0.959 0.041 0.000
G63.2 Diabetic polyneuropathy
0.959 0.041 0.000
G62.9 Polyneuropathy, unspecified
0.959 0.041 0.000
I85.9 Oesophageal varices without bleeding
0.959 0.041 0.000
M82 Osteoporosis in diseases classified elsewhere
0.959 0.041 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.959 0.041 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.958 0.042 0.000
Y40.0 Penicillins
0.958 0.042 0.000
B99-B99 Other infectious diseases
0.958 0.042 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.958 0.042 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.958 0.042 0.000
Z03.2 Observation for suspected mental and behavioural disorders
0.957 0.043 0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)
0.957 0.043 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.957 0.043 0.000
B37.9 Candidiasis, unspecified
0.957 0.043 0.000
H90-H95 Other disorders of ear
0.957 0.043 0.000
G90 Disorders of autonomic nervous system
0.956 0.044 0.000
Z73 Problems related to life-management difficulty
0.956 0.044 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.955 0.045 0.000
Z03.3 Observation for suspected nervous system disorder
0.954 0.046 0.000
W08 Fall involving other furniture
0.954 0.046 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.954 0.046 0.000
M21.2 Flexion deformity
0.953 0.047 0.000
S81 Open wound of lower leg
0.953 0.047 0.000
S52 Fracture of forearm
0.953 0.047 0.000
K76.6 Portal hypertension
0.953 0.047 0.000
C81 Hodgkin's disease
0.952 0.048 0.000
Z83.4 Family history of other endocrine, nutritional and metabolic diseases
0.952 0.048 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.952 0.048 0.000
H53.1 Subjective visual disturbances
0.952 0.048 0.000
S42.0 Fracture of clavicle
0.952 0.048 0.000
H90 Conductive and sensorineural hearing loss
0.951 0.049 0.000
R82.7 Abnormal findings on microbiological examination of urine
0.950 0.050 0.000
N76.8 Other specified inflammation of vagina and vulva
0.950 0.050 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.949 0.051 0.000
M54.3 Sciatica
0.949 0.051 0.000
B00 Herpesviral [herpes simplex] infections
0.948 0.052 0.000
N18.4 Chronic kidney disease, stage 4
0.947 0.053 0.000
H34 Retinal vascular occlusions
0.947 0.053 0.000
W22.9 Unspecified place
0.947 0.053 0.000
Z48.0 Attention to surgical dressings and sutures
0.947 0.053 0.000
W10 Fall on and from stairs and steps
0.946 0.054 0.000
N99-N99 Other disorders of the genitourinary system
0.946 0.054 0.000
Z63 Other problems related to primary support group, including family circumstances
0.946 0.054 0.000
B37.3 Candidiasis of vulva and vagina
0.946 0.054 0.000
M79.2 Neuralgia and neuritis, unspecified
0.945 0.055 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.945 0.055 0.000
M54.22 Cervicalgia (Cervical region)
0.945 0.055 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.944 0.056 0.000
Y43.1 Antineoplastic antimetabolites
0.944 0.056 0.000
N05 Unspecified nephritic syndrome
0.944 0.056 0.000
J95-J99 Other diseases of the respiratory system
0.944 0.056 0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
0.943 0.057 0.000
Z71.3 Dietary counselling and surveillance
0.941 0.059 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.940 0.060 0.000
H57 Other disorders of eye and adnexa
0.940 0.060 0.000
M24.27 Disorder of ligament (Ankle and foot)
0.940 0.060 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.939 0.061 0.000
Y85 Sequelae of transport accidents
0.938 0.062 0.000
S12.2 Fracture of other specified cervical vertebra
0.938 0.062 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.937 0.063 0.000
Z99.8 Dependence on other enabling machines and devices
0.937 0.063 0.000
K52.1 Toxic gastro-enteritis and colitis
0.936 0.064 0.000
N04.9 Unspecified
0.935 0.065 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.935 0.065 0.000
K52.3 Indeterminate colitis
0.935 0.065 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.934 0.066 0.000
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere
0.933 0.067 0.000
M79.1 Myalgia
0.932 0.068 0.000
H61.1 Non-infective disorders of pinna
0.932 0.068 0.000
Y52 Agents primarily affecting the cardiovascular system
0.932 0.068 0.000
I87 Other disorders of veins
0.931 0.069 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.931 0.069 0.000
D55-D59 Haemolytic anaemias
0.931 0.069 0.000
S42.3 Fracture of shaft of humerus
0.931 0.069 0.000
S40 Superficial injury of shoulder and upper arm
0.931 0.069 0.000
S06 Intracranial injury
0.931 0.069 0.000
R25.1 Tremor, unspecified
0.931 0.069 0.000
H47.3 Other disorders of optic disk
0.930 0.070 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.930 0.070 0.000
M82.1 Osteoporosis in endocrine disorders
0.930 0.070 0.000
M79.0 Rheumatism, unspecified
0.929 0.071 0.000
S70-S79 Injuries to the hip and thigh
0.929 0.071 0.000
H21 Other disorders of iris and ciliary body
0.929 0.071 0.000
T86 Failure and rejection of transplanted organs and tissues
0.929 0.071 0.000
Q51 Congenital malformations of uterus and cervix
0.929 0.071 0.000
B99 Other and unspecified infectious diseases
0.928 0.072 0.000
S52.6 Fracture of lower end of both ulna and radius
0.928 0.072 0.000
Z89.0 Acquired absence of finger(s) [including thumb], unilateral
0.928 0.072 0.000
S92 Fracture of foot, except ankle
0.928 0.072 0.000
M54.50 Low back pain (Multiple sites in spine)
0.928 0.072 0.000
M46 Other inflammatory spondylopathies
0.927 0.073 0.000
V20-V29 Motorcycle rider injured in transport accident
0.927 0.073 0.000
W50-W64 Exposure to animate mechanical forces
0.927 0.073 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.927 0.073 0.000
E00-E07 Disorders of thyroid gland
0.926 0.074 0.000
T63 Toxic effect of contact with venomous animals
0.926 0.074 0.000
S41.1 Open wound of upper arm
0.926 0.074 0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)
0.925 0.075 0.000
H54.0 Blindness, both eyes
0.925 0.075 0.000
Y40.3 Macrolides
0.925 0.075 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.925 0.075 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.925 0.075 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.924 0.076 0.000
E20-E35 Disorders of other endocrine glands
0.923 0.077 0.000
I95.1 Orthostatic hypotension
0.923 0.077 0.000
S42.00 Fracture of clavicle (closed)
0.922 0.078 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.922 0.078 0.000
M90 Osteopathies in diseases classified elsewhere
0.921 0.079 0.000
M71.3 Other bursal cyst
0.921 0.079 0.000
K50 Crohn's disease [regional enteritis]
0.920 0.080 0.000
G61 Inflammatory polyneuropathy
0.920 0.080 0.000
M40-M43 Deforming dorsopathies
0.920 0.080 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.920 0.080 0.000
K70.1 Alcoholic hepatitis
0.920 0.080 0.000
M65 Synovitis and tenosynovitis
0.919 0.081 0.000
G70-G73 Diseases of myoneural junction and muscle
0.919 0.081 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.919 0.081 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.918 0.082 0.000
Y84.6 Urinary catheterisation
0.917 0.083 0.000
S14 Injury of nerves and spinal cord at neck level
0.915 0.085 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.915 0.085 0.000
N03 Chronic nephritic syndrome
0.913 0.087 0.000
M87 Osteonecrosis
0.911 0.089 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.911 0.089 0.000
D69.5 Secondary thrombocytopenia
0.911 0.089 0.000
F30.0 Hypomania
0.910 0.090 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.909 0.091 0.000
Q28 Other congenital malformations of circulatory system
0.909 0.091 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.907 0.093 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.907 0.093 0.000
M24.5 Contracture of joint
0.907 0.093 0.000
B37.1 Pulmonary candidiasis
0.906 0.094 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.906 0.094 0.000
K58.0 Irritable bowel syndrome with diarrhoea
0.906 0.094 0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)
0.905 0.095 0.000
S12.20 Fracture of other specified cervical vertebra (closed)
0.905 0.095 0.000
M21.0 Valgus deformity, not elsewhere classified
0.905 0.095 0.000
R25.8 Other and unspecified abnormal involuntary movements
0.904 0.096 0.000
S91 Open wound of ankle and foot
0.904 0.096 0.000
Z71.2 Person consulting for explanation of investigation findings
0.904 0.096 0.000
T66-T78 Other and unspecified effects of external causes
0.903 0.097 0.000
L50-L54 Urticaria and erythema
0.903 0.097 0.000
H35.2 Other proliferative retinopathy
0.902 0.098 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.902 0.098 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.902 0.098 0.000
M79.8 Other specified soft tissue disorders
0.902 0.098 0.000
S42.4 Fracture of lower end of humerus
0.902 0.098 0.000
W07 Fall involving chair
0.902 0.098 0.000
H57.0 Anomalies of pupillary function
0.901 0.099 0.000
M79.7 Fibromyalgia
0.900 0.100 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.900 0.100 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.900 0.100 0.000
F34 Persistent mood [affective] disorders
0.900 0.100 0.000
H70 Mastoiditis and related conditions
0.899 0.101 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.899 0.101 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.899 0.101 0.000
D68.0 Von Willebrand's disease
0.899 0.101 0.000
Z48.9 Surgical follow-up care, unspecified
0.898 0.102 0.000
E10.3 With ophthalmic complications
0.897 0.103 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.896 0.104 0.000
S02.5 Fracture of tooth
0.896 0.104 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.896 0.104 0.000
G97.1 Other reaction to spinal and lumbar puncture
0.895 0.105 0.000
M24.23 Disorder of ligament (Forearm)
0.895 0.105 0.000
Y85.0 Sequelae of motor-vehicle accident
0.895 0.105 0.000
R84 Abnormal findings in specimens from respiratory organs and thorax
0.895 0.105 0.000
H60.9 Otitis externa, unspecified
0.895 0.105 0.000
Y40.8 Other systemic antibiotics
0.895 0.105 0.000
T93.0 Sequelae of open wound of lower limb
0.895 0.105 0.000
W08.0 Home
0.895 0.105 0.000
K61 Abscess of anal and rectal regions
0.895 0.105 0.000
M75 Shoulder lesions
0.894 0.106 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.894 0.106 0.000
S52.60 Fracture of lower end of both ulna and radius (closed)
0.894 0.106 0.000
D68.6 Other Thrombophilia
0.893 0.107 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.893 0.107 0.000
M54.6 Pain in thoracic spine
0.893 0.107 0.000
G90.0 Idiopathic peripheral autonomic neuropathy
0.893 0.107 0.000
S20-S29 Injuries to the thorax
0.892 0.108 0.000
M10.90 Gout, unspecified (Multiple sites)
0.892 0.108 0.000
C34.3 Lower lobe, bronchus or lung
0.892 0.108 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.892 0.108 0.000
M06.0 Seronegative rheumatoid arthritis
0.892 0.108 0.000
D80-D89 Certain disorders involving the immune mechanism
0.892 0.108 0.000
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.892 0.108 0.000
K70.0 Alcoholic fatty liver
0.891 0.109 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.891 0.109 0.000
Z73.3 Stress, not elsewhere classified
0.891 0.109 0.000
G03 Meningitis due to other and unspecified causes
0.891 0.109 0.000
H69 Other disorders of Eustachian tube
0.891 0.109 0.000
K50.8 Other Crohn's disease
0.890 0.110 0.000
C32 Malignant neoplasm of larynx
0.890 0.110 0.000
C34.2 Middle lobe, bronchus or lung
0.888 0.112 0.000
M25 Other joint disorders, not elsewhere classified
0.888 0.112 0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.888 0.112 0.000
S42.30 Fracture of shaft of humerus (closed)
0.887 0.113 0.000
W10.8 Other specified place
0.887 0.113 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.887 0.113 0.000
M47.9 Spondylosis, unspecified
0.886 0.114 0.000
T91 Sequelae of injuries of neck and trunk
0.886 0.114 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.886 0.114 0.000
M89.8 Other specified disorders of bone
0.886 0.114 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.886 0.114 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.885 0.115 0.000
K70.9 Alcoholic liver disease, unspecified
0.884 0.116 0.000
T58 Toxic effect of carbon monoxide
0.884 0.116 0.000
I86 Varicose veins of other sites
0.884 0.116 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.883 0.117 0.000
A46 Erysipelas
0.883 0.117 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.883 0.117 0.000
S81.8 Open wound of other parts of lower leg
0.883 0.117 0.000
E04 Other non-toxic goitre
0.882 0.118 0.000
D59 Acquired haemolytic anaemia
0.882 0.118 0.000
A40 Streptococcal septicaemia
0.882 0.118 0.000
C81.9 Hodgkin's disease, unspecified
0.882 0.118 0.000
T63.4 Venom of other arthropods
0.882 0.118 0.000
L29 Pruritus
0.881 0.119 0.000
H47.1 Papilloedema, unspecified
0.881 0.119 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.880 0.120 0.000
W19 Unspecified fall
0.880 0.120 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.880 0.120 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.879 0.121 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.878 0.122 0.000
M79.6 Pain in limb
0.878 0.122 0.000
M85 Other disorders of bone density and structure
0.877 0.123 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.876 0.124 0.000
H61.0 Perichondritis of external ear
0.875 0.125 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.875 0.125 0.000
L23 Allergic contact dermatitis
0.875 0.125 0.000
V10-V19 Pedal cyclist injured in transport accident
0.874 0.126 0.000
S00 Superficial injury of head
0.873 0.127 0.000
F52.2 Failure of genital response
0.873 0.127 0.000
M21.27 Flexion deformity (Ankle and foot)
0.872 0.128 0.000
H18 Other disorders of cornea
0.872 0.128 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.872 0.128 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.871 0.129 0.000
Z89.4 Acquired absence of foot and ankle
0.870 0.130 0.000
I82 Other venous embolism and thrombosis
0.869 0.131 0.000
N71 Inflammatory disease of uterus, except cervix
0.869 0.131 0.000
N99.0 Postprocedural renal failure
0.869 0.131 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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