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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs295130
log Bayes Factor = 24.0264
Chromosome 2   position 201,229,984  (GRCh37) Explore rs295130 on Ensembl!
Variant rs295130 is part of Cluster X0209

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
Chapter XX External causes of morbidity and mortality
0.999 0.001 0.000
D60-D64 Aplastic and other anaemias
0.999 0.001 0.000
Chapter XXI Factors influencing health status and contact with health services
0.999 0.001 0.000
Chapter VII Diseases of the eye and adnexa
0.999 0.001 0.000
H53-H54 Visual disturbances and blindness
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
H53 Visual disturbances
0.996 0.004 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.995 0.005 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.994 0.006 0.000
Z51 Other medical care
0.994 0.006 0.000
M05-M14 Inflammatory polyarthropathies
0.994 0.006 0.000
Chapter I Certain infectious and parasitic diseases
0.993 0.007 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.992 0.008 0.000
M06 Other rheumatoid arthritis
0.984 0.016 0.000
Z51.3 Blood transfusion without reported diagnosis
0.983 0.017 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.982 0.018 0.000
Chapter XIV Diseases of the genitourinary system
0.981 0.019 0.000
H54 Blindness and low vision
0.980 0.020 0.000
D61 Other aplastic anaemias
0.980 0.020 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.979 0.021 0.000
D64 Other anaemias
0.979 0.021 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.979 0.021 0.000
E10-E14 Diabetes mellitus
0.979 0.021 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.975 0.025 0.000
M20-M25 Other joint disorders
0.975 0.025 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.972 0.028 0.000
M06.9 Rheumatoid arthritis, unspecified
0.967 0.033 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.967 0.033 0.000
D61.9 Aplastic anaemia, unspecified
0.967 0.033 0.000
M25 Other joint disorders, not elsewhere classified
0.961 0.039 0.000
D64.9 Anaemia, unspecified
0.960 0.040 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.958 0.042 0.000
Z51.2 Other chemotherapy
0.958 0.042 0.000
M10 Gout
0.955 0.045 0.000
Q50-Q56 Congenital malformations of genital organs
0.950 0.050 0.000
I77 Other disorders of arteries and arterioles
0.947 0.053 0.000
Chapter V Mental and behavioural disorders
0.946 0.054 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.945 0.055 0.000
F31 Bipolar affective disorder
0.944 0.056 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.944 0.056 0.000
F30-F39 Mood [affective] disorders
0.944 0.056 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.939 0.061 0.000
E11 Non-insulin-dependent diabetes mellitus
0.938 0.062 0.000
I85 Oesophageal varices
0.937 0.063 0.000
F31.9 Bipolar affective disorder, unspecified
0.935 0.065 0.000
S40-S49 Injuries to the shoulder and upper arm
0.935 0.065 0.000
H53.1 Subjective visual disturbances
0.934 0.066 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.933 0.067 0.000
S00-S09 Injuries to the head
0.933 0.067 0.000
I80 Phlebitis and thrombophlebitis
0.931 0.069 0.000
Z48 Other surgical follow-up care
0.931 0.069 0.000
Z60 Problems related to social environment
0.928 0.072 0.000
M10.9 Gout, unspecified
0.928 0.072 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.928 0.072 0.000
H53.9 Visual disturbance, unspecified
0.925 0.075 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.923 0.077 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.922 0.078 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.921 0.079 0.000
S90-S99 Injuries to the ankle and foot
0.920 0.080 0.000
N99-N99 Other disorders of the genitourinary system
0.917 0.083 0.000
B95-B98 Bacterial, viral and other infectious agents
0.917 0.083 0.000
I77.1 Stricture of artery
0.916 0.084 0.000
S10-S19 Injuries to the neck
0.916 0.084 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.914 0.086 0.000
H53.2 Diplopia
0.913 0.087 0.000
H55-H59 Other disorders of eye and adnexa
0.913 0.087 0.000
R04 Haemorrhage from respiratory passages
0.911 0.089 0.000
Y40 Systemic antibiotics
0.911 0.089 0.000
Y43 Primarily systemic agents
0.909 0.091 0.000
D62 Acute posthaemorrhagic anaemia
0.906 0.093 0.000
M40-M43 Deforming dorsopathies
0.905 0.095 0.000
H54.0 Blindness, both eyes
0.904 0.096 0.000
Z51.8 Other specified medical care
0.904 0.096 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.904 0.096 0.000
Z60.2 Living alone
0.900 0.100 0.000
M25.7 Osteophyte
0.899 0.101 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.899 0.101 0.000
B25-B34 Other viral diseases
0.897 0.103 0.000
R01 Cardiac murmurs and other cardiac sounds
0.897 0.103 0.000
I85.9 Oesophageal varices without bleeding
0.896 0.104 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.895 0.105 0.000
N72 Inflammatory disease of cervix uteri
0.894 0.106 0.000
R29.6 Tendency to fall, not elsewhere classified
0.894 0.106 0.000
S01 Open wound of head
0.893 0.107 0.000
X60-X84 Intentional self-harm
0.889 0.111 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.889 0.111 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.887 0.113 0.000
N25-N29 Other disorders of kidney and ureter
0.886 0.114 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.884 0.116 0.000
E00-E07 Disorders of thyroid gland
0.883 0.117 0.000
Y42.7 Androgens and anabolic congeners
0.882 0.118 0.000
H53.4 Visual field defects
0.882 0.118 0.000
N76 Other inflammation of vagina and vulva
0.881 0.119 0.000
I73 Other peripheral vascular diseases
0.880 0.120 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.880 0.120 0.000
N73 Other female pelvic inflammatory diseases
0.877 0.123 0.000
V80-V89 Other land transport accidents
0.877 0.123 0.000
S01.0 Open wound of scalp
0.877 0.123 0.000
R04.0 Epistaxis
0.876 0.124 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.875 0.125 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.875 0.125 0.000
Z48.9 Surgical follow-up care, unspecified
0.874 0.126 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.874 0.126 0.000
I78 Diseases of capillaries
0.873 0.127 0.000
M06.0 Seronegative rheumatoid arthritis
0.873 0.127 0.000
Q50.4 Embryonic cyst of Fallopian tube
0.871 0.129 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.871 0.129 0.000
E10 Insulin-dependent diabetes mellitus
0.869 0.131 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.869 0.131 0.000
Y43.3 Other antineoplastic drugs
0.868 0.132 0.000
R01.1 Cardiac murmur, unspecified
0.868 0.132 0.000
E11.3 With ophthalmic complications
0.868 0.132 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.866 0.134 0.000
Chapter VIII Diseases of the ear and mastoid process
0.865 0.135 0.000
H30-H36 Disorders of choroid and retina
0.863 0.137 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.861 0.139 0.000
H54.4 Blindness, one eye
0.861 0.139 0.000
E04 Other non-toxic goitre
0.857 0.143 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.857 0.143 0.000
N00-N08 Glomerular diseases
0.855 0.145 0.000
M25.8 Other specified joint disorders
0.855 0.145 0.000
M10.99 Gout, unspecified (Site unspecified)
0.854 0.146 0.000
Y40.0 Penicillins
0.853 0.147 0.000
B35-B49 Mycoses
0.849 0.151 0.000
I73.9 Peripheral vascular disease, unspecified
0.848 0.152 0.000
D55-D59 Haemolytic anaemias
0.847 0.153 0.000
E50-E64 Other nutritional deficiencies
0.843 0.157 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.843 0.157 0.000
S02 Fracture of skull and facial bones
0.842 0.158 0.000
B34 Viral infection of unspecified site
0.842 0.158 0.000
E20-E35 Disorders of other endocrine glands
0.840 0.160 0.000
T81 Complications of procedures, not elsewhere classified
0.840 0.160 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.838 0.162 0.000
H53.8 Other visual disturbances
0.838 0.162 0.000
E65-E68 Obesity and other hyperalimentation
0.837 0.163 0.000
T39.1 4-Aminophenol derivatives
0.834 0.166 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.832 0.168 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.832 0.168 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.831 0.169 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.830 0.170 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.829 0.171 0.000
R82 Other abnormal findings in urine
0.829 0.171 0.000
Q51 Congenital malformations of uterus and cervix
0.828 0.172 0.000
Z41 Procedures for purposes other than remedying health state
0.827 0.173 0.000
D80-D89 Certain disorders involving the immune mechanism
0.826 0.174 0.000
E04.1 Non-toxic single thyroid nodule
0.826 0.174 0.000
N73.6 Female pelvic peritoneal adhesions
0.825 0.175 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.825 0.175 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.824 0.176 0.000
S41 Open wound of shoulder and upper arm
0.824 0.176 0.000
W00-W19 Falls
0.823 0.177 0.000
I87 Other disorders of veins
0.822 0.178 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.822 0.178 0.000
S42 Fracture of shoulder and upper arm
0.821 0.179 0.000
S80-S89 Injuries to the knee and lower leg
0.820 0.180 0.000
Z51.9 Medical care, unspecified
0.818 0.182 0.000
M21 Other acquired deformities of limbs
0.818 0.182 0.000
H57 Other disorders of eye and adnexa
0.817 0.183 0.000
M25.74 Osteophyte (Hand)
0.817 0.183 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.816 0.184 0.000
A80-A89 Viral infections of the central nervous system
0.815 0.185 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.813 0.187 0.000
M43 Other deforming dorsopathies
0.808 0.192 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.808 0.192 0.000
H54.2 Low vision, both eyes
0.807 0.193 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.807 0.193 0.000
O60-O75 Complications of labour and delivery
0.807 0.193 0.000
T39.0 Salicylates
0.806 0.194 0.000
I81 Portal vein thrombosis
0.804 0.196 0.000
I20-I25 Ischaemic heart diseases
0.804 0.196 0.000
I60-I69 Cerebrovascular diseases
0.803 0.197 0.000
N60-N64 Disorders of breast
0.803 0.197 0.000
I78.1 Naevus, nonneoplastic
0.802 0.198 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.801 0.199 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.801 0.199 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.800 0.199 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.800 0.200 0.000
R02 Gangrene, not elsewhere classified
0.800 0.200 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.799 0.200 0.000
A30-A49 Other bacterial diseases
0.799 0.201 0.000
N30-N39 Other diseases of urinary system
0.798 0.202 0.000
N99.8 Other postprocedural disorders of genito-urinary system
0.798 0.202 0.000
E13 Other specified diabetes mellitus
0.798 0.202 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.797 0.203 0.000
I99 Other and unspecified disorders of circulatory system
0.797 0.203 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.797 0.203 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.795 0.205 0.000
H65-H75 Diseases of middle ear and mastoid
0.795 0.205 0.000
N35 Urethral stricture
0.795 0.205 0.000
N71 Inflammatory disease of uterus, except cervix
0.794 0.206 0.000
E11.4 With neurological complications
0.794 0.206 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.793 0.206 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.793 0.207 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.792 0.208 0.000
W20-W49 Exposure to inanimate mechanical forces
0.791 0.209 0.000
F34 Persistent mood [affective] disorders
0.791 0.209 0.000
B34.9 Viral infection, unspecified
0.790 0.210 0.000
Z13 Special screening examination for other diseases and disorders
0.790 0.210 0.000
I60 Subarachnoid haemorrhage
0.787 0.213 0.000
N35.9 Urethral stricture, unspecified
0.784 0.216 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.784 0.216 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.783 0.217 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.783 0.217 0.000
X10-X19 Contact with heat and hot substances
0.783 0.217 0.000
M45-M49 Spondylopathies
0.782 0.218 0.000
S12 Fracture of neck
0.781 0.219 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.780 0.220 0.000
O85-O92 Complications predominantly related to the puerperium
0.779 0.221 0.000
Z40 Prophylactic surgery
0.777 0.223 0.000
M70-M79 Other soft tissue disorders
0.777 0.223 0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.776 0.224 0.000
V20-V29 Motorcycle rider injured in transport accident
0.775 0.224 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.774 0.226 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.774 0.226 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.773 0.227 0.000
M25.3 Other instability of joint
0.773 0.227 0.000
M86-M90 Other osteopathies
0.773 0.227 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.772 0.228 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.772 0.228 0.000
A00-A09 Intestinal infectious diseases
0.771 0.229 0.000
Z59 Problems related to housing and economic circumstances
0.769 0.231 0.000
H34 Retinal vascular occlusions
0.768 0.232 0.000
M25.76 Osteophyte (Lower leg)
0.767 0.233 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.767 0.233 0.000
D68 Other coagulation defects
0.767 0.233 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.766 0.234 0.000
D64.8 Other specified anaemias
0.765 0.235 0.000
Chapter VI Diseases of the nervous system
0.765 0.235 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.764 0.236 0.000
M31 Other necrotising vasculopathies
0.763 0.237 0.000
M50-M54 Other dorsopathies
0.763 0.237 0.000
N76.4 Abscess of vulva
0.763 0.237 0.000
R06 Abnormalities of breathing
0.762 0.238 0.000
M10.96 Gout, unspecified (Lower leg)
0.761 0.239 0.000
R82.9 Other and unspecified abnormal finding in urine
0.761 0.239 0.000
M24 Other specific joint derangements
0.761 0.239 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.761 0.239 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.760 0.240 0.000
T40.4 Other synthetic narcotics
0.760 0.240 0.000
S14 Injury of nerves and spinal cord at neck level
0.760 0.240 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.760 0.240 0.000
H54.9 Unspecified visual impairment (binocular)
0.760 0.240 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.759 0.241 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.759 0.241 0.000
S01.4 Open wound of cheek and temporomandibular area
0.759 0.241 0.000
S81 Open wound of lower leg
0.758 0.242 0.000
S40 Superficial injury of shoulder and upper arm
0.758 0.242 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.757 0.243 0.000
D50-D53 Nutritional anaemias
0.756 0.244 0.000
N03 Chronic nephritic syndrome
0.756 0.244 0.000
H54.7 Unspecified visual loss
0.756 0.244 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.755 0.245 0.000
H74 Other disorders of middle ear and mastoid
0.754 0.246 0.000
F39 Unspecified mood [affective] disorder
0.754 0.246 0.000
B99-B99 Other infectious diseases
0.754 0.246 0.000
Z49 Care involving dialysis
0.752 0.248 0.000
R25 Abnormal involuntary movements
0.752 0.248 0.000
H40-H42 Glaucoma
0.752 0.248 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.751 0.249 0.000
S92 Fracture of foot, except ankle
0.750 0.250 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.749 0.251 0.000
E11.9 Without complications
0.749 0.251 0.000
M25.81 Other specified joint disorders (Shoulder region)
0.749 0.251 0.000
M25.4 Effusion of joint
0.749 0.251 0.000
H36 Retinal disorders in diseases classified elsewhere
0.748 0.252 0.000
X62.9 Unspecified place
0.748 0.252 0.000
H57.9 Disorder of eye and adnexa, unspecified
0.747 0.253 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.747 0.253 0.000
M33 Dermatopolymyositis
0.746 0.254 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.745 0.255 0.000
S50-S59 Injuries to the elbow and forearm
0.745 0.255 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.745 0.255 0.000
Y00-Y09 Assault
0.744 0.255 0.000
S41.1 Open wound of upper arm
0.744 0.256 0.000
E10.4 With neurological complications
0.744 0.256 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.744 0.256 0.000
H55 Nystagmus and other irregular eye movements
0.743 0.257 0.000
I85.0 Oesophageal varices with bleeding
0.743 0.257 0.000
S02.2 Fracture of nasal bones
0.742 0.258 0.000
E11.2 With renal complications
0.742 0.258 0.000
Z52 Donors of organs and tissues
0.742 0.258 0.000
V80 Animal-rider or occupant of animal-drawn vehicle injured in transport accident
0.742 0.258 0.000
S70-S79 Injuries to the hip and thigh
0.741 0.259 0.000
Q51.3 Bicornate uterus
0.741 0.259 0.000
R04.2 Haemoptysis
0.740 0.260 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.740 0.260 0.000
S89 Other and unspecified injuries of lower leg
0.739 0.260 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.738 0.262 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.738 0.262 0.000
D59 Acquired haemolytic anaemia
0.737 0.263 0.000
S02.3 Fracture of orbital floor
0.737 0.263 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.737 0.263 0.000
S90 Superficial injury of ankle and foot
0.736 0.263 0.000
R20 Disturbances of skin sensation
0.736 0.264 0.000
M00-M03 Infectious arthropathies
0.736 0.264 0.000
B35 Dermatophytosis
0.736 0.264 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.736 0.264 0.000
N28.8 Other specified disorders of kidney and ureter
0.736 0.264 0.000
M91-M94 Chondropathies
0.736 0.264 0.000
I95 Hypotension
0.735 0.265 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.734 0.266 0.000
T79-T79 Certain early complications of trauma
0.733 0.266 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.733 0.267 0.000
N99.4 Postprocedural pelvic peritoneal adhesions
0.732 0.267 0.000
M10.94 Gout, unspecified (Hand)
0.732 0.268 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.732 0.268 0.000
Y95 Nosocomial condition
0.731 0.269 0.000
T82.1 Mechanical complication of cardiac electronic device
0.731 0.269 0.000
I77.6 Arteritis, unspecified
0.731 0.269 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.730 0.269 0.000
S99 Other and unspecified injuries of ankle and foot
0.730 0.270 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.730 0.270 0.000
M43.1 Spondylolisthesis
0.729 0.271 0.000
I87.1 Compression of vein
0.729 0.271 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.729 0.271 0.000
D69 Purpura and other haemorrhagic conditions
0.729 0.271 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.728 0.272 0.000
Y40.8 Other systemic antibiotics
0.728 0.272 0.000
Z57 Occupational exposure to risk-factors
0.728 0.272 0.000
E55 Vitamin D deficiency
0.726 0.274 0.000
Z58 Problems related to physical environment
0.726 0.274 0.000
W50-W64 Exposure to animate mechanical forces
0.725 0.275 0.000
O73 Retained placenta and membranes, without haemorrhage
0.725 0.275 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.725 0.275 0.000
N35.8 Other urethral stricture
0.725 0.275 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.724 0.276 0.000
D86 Sarcoidosis
0.724 0.276 0.000
E66 Obesity
0.724 0.276 0.000
S42.3 Fracture of shaft of humerus
0.723 0.277 0.000
S06 Intracranial injury
0.723 0.277 0.000
E06 Thyroiditis
0.723 0.277 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.723 0.277 0.000
R82.7 Abnormal findings on microbiological examination of urine
0.722 0.278 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.721 0.279 0.000
S91 Open wound of ankle and foot
0.720 0.280 0.000
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere
0.719 0.281 0.000
Z03.4 Observation for suspected myocardial infarction
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X20-X29 Contact with venomous animals and plants
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.717 0.283 0.000
W75-W84 Other accidental threats to breathing
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.717 0.283 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.716 0.283 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.716 0.284 0.000
N76.1 Subacute and chronic vaginitis
0.716 0.284 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.715 0.285 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.715 0.285 0.000
N04 Nephrotic syndrome
0.715 0.285 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.714 0.286 0.000
I70 Atherosclerosis
0.714 0.286 0.000
H53.6 Night blindness
0.714 0.286 0.000
H53.5 Colour vision deficiencies
0.714 0.286 0.000
H53.3 Other disorders of binocular vision
0.714 0.286 0.000
T40.2 Other opioids
0.714 0.286 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.714 0.286 0.000
Z44 Fitting and adjustment of external prosthetic device
0.714 0.286 0.000
S19 Other and unspecified injuries of neck
0.714 0.286 0.000
I22 Subsequent myocardial infarction
0.713 0.287 0.000
Z51.6 Desensitisation to allergens
0.713 0.287 0.000
M40 Kyphosis and lordosis
0.713 0.287 0.000
M12 Other specific arthropathies
0.713 0.287 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.713 0.287 0.000
M08 Juvenile arthritis
0.713 0.287 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.712 0.288 0.000
I24 Other acute ischaemic heart diseases
0.712 0.288 0.000
M22 Disorders of patella
0.712 0.288 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.712 0.288 0.000
B65-B83 Helminthiases
0.712 0.288 0.000
B50-B64 Protozoal diseases
0.712 0.288 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.712 0.288 0.000
A75-A79 Rickettsioses
0.712 0.288 0.000
A70-A74 Other diseases caused by chlamydiae
0.712 0.288 0.000
A65-A69 Other spirochaetal diseases
0.712 0.288 0.000
A20-A28 Certain zoonotic bacterial diseases
0.712 0.288 0.000
A15-A19 Tuberculosis
0.712 0.288 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.711 0.288 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.711 0.288 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.711 0.288 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.711 0.288 0.000
T36 Poisoning by systemic antibiotics
0.711 0.288 0.000
Z03.2 Observation for suspected mental and behavioural disorders
0.711 0.289 0.000
R80 Isolated proteinuria
0.709 0.291 0.000
M10.90 Gout, unspecified (Multiple sites)
0.708 0.292 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.708 0.292 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.707 0.293 0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance
0.707 0.293 0.000
Z03.1 Observation for suspected malignant neoplasm
0.707 0.293 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.707 0.293 0.000
H10-H13 Disorders of conjunctiva
0.707 0.293 0.000
E04.2 Non-toxic multinodular goitre
0.706 0.294 0.000
M06.8 Other specified rheumatoid arthritis
0.706 0.294 0.000
M06.4 Inflammatory polyarthropathy
0.706 0.294 0.000
M06.3 Rheumatoid nodule
0.706 0.294 0.000
M06.2 Rheumatoid bursitis
0.706 0.294 0.000
M06.1 Adult-onset Still's disease
0.706 0.294 0.000
Z51.5 Palliative care
0.704 0.296 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.704 0.296 0.000
T82.3 Mechanical complication of other vascular grafts
0.704 0.296 0.000
N61 Inflammatory disorders of breast
0.703 0.297 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.703 0.297 0.000
H54.6 Unqualified visual loss, one eye
0.703 0.297 0.000
H54.5 Low vision, one eye
0.703 0.297 0.000
H54.3 Unqualified visual loss, both eyes
0.703 0.297 0.000
H54.1 Blindness, one eye, low vision, other eye
0.703 0.297 0.000
D61.8 Other specified aplastic anaemias
0.703 0.297 0.000
D61.3 Idiopathic aplastic anaemia
0.703 0.297 0.000
D61.2 Aplastic anaemia due to other external agents
0.703 0.297 0.000
D61.1 Drug-induced aplastic anaemia
0.703 0.297 0.000
D61.0 Constitutional aplastic anaemia
0.703 0.297 0.000
M34 Systemic sclerosis
0.703 0.297 0.000
M54 Dorsalgia
0.702 0.298 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.702 0.298 0.000
Q35-Q37 Cleft lip and cleft palate
0.702 0.298 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.702 0.298 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.702 0.298 0.000
W10 Fall on and from stairs and steps
0.702 0.298 0.000
D64.4 Congenital dyserythropoietic anaemia
0.702 0.298 0.000
D64.3 Other sideroblastic anaemias
0.702 0.298 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.702 0.298 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.702 0.298 0.000
D64.0 Hereditary sideroblastic anaemia
0.702 0.298 0.000
I88 Nonspecific lymphadenitis
0.702 0.298 0.000
E12 Malnutrition-related diabetes mellitus
0.702 0.298 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.701 0.299 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.701 0.299 0.000
N76.5 Ulceration of vagina
0.701 0.299 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.701 0.299 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.700 0.300 0.000
M07 Psoriatic and enteropathic arthropathies
0.700 0.300 0.000
Z48.0 Attention to surgical dressings and sutures
0.699 0.301 0.000
Y59 Other and unspecified vaccines and biological substances
0.699 0.301 0.000
Y58 Bacterial vaccines
0.699 0.301 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.699 0.301 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.699 0.301 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.699 0.301 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.699 0.301 0.000
Y48 Anaesthetics and therapeutic gases
0.699 0.301 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.699 0.301 0.000
V40-V49 Car occupant injured in transport accident
0.699 0.301 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.699 0.301 0.000
M32 Systemic lupus erythematosus
0.699 0.301 0.000
M30 Polyarteritis nodosa and related conditions
0.699 0.301 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.698 0.302 0.000
H34.8 Other retinal vascular occlusions
0.698 0.302 0.000
E11.1 With ketoacidosis
0.697 0.303 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.697 0.303 0.000
Y43.1 Antineoplastic antimetabolites
0.696 0.304 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.696 0.304 0.000
S42.0 Fracture of clavicle
0.695 0.304 0.000
H74.8 Other specified disorders of middle ear and mastoid
0.695 0.304 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.695 0.305 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.694 0.306 0.000
M25.5 Pain in joint
0.694 0.306 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.694 0.306 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.694 0.306 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.694 0.306 0.000
Z65 Problems related to other psychosocial circumstances
0.694 0.306 0.000
Z64 Problems related to certain psychosocial circumstances
0.694 0.306 0.000
Z62 Other problems related to upbringing
0.694 0.306 0.000
Z61 Problems related to negative life events in childhood
0.694 0.306 0.000
Z56 Problems related to employment and unemployment
0.694 0.306 0.000
Z55 Problems related to education and literacy
0.694 0.306 0.000
O62 Abnormalities of forces of labour
0.693 0.307 0.000
X50-X57 Overexertion, travel and privation
0.692 0.308 0.000
Q60-Q64 Congenital malformations of the urinary system
0.692 0.308 0.000
M11 Other crystal arthropathies
0.692 0.308 0.000
S20-S29 Injuries to the thorax
0.692 0.308 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.692 0.308 0.000
Q23 Congenital malformations of aortic and mitral valves
0.689 0.311 0.000
Z75 Problems related to medical facilities and other health care
0.689 0.311 0.000
M25.2 Flail joint
0.689 0.311 0.000
M25.1 Fistula of joint
0.689 0.311 0.000
M25.0 Haemarthrosis
0.689 0.311 0.000
E10.2 With renal complications
0.689 0.311 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.688 0.311 0.000
Z48.8 Other specified surgical follow-up care
0.688 0.312 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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