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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1063355
log Bayes Factor = 441.898
Chromosome 6   position 32,627,714  (GRCh37) Explore rs1063355 on Ensembl!
Variant rs1063355 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
D64.9 Anaemia, unspecified
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
J33.9 Nasal polyp, unspecified
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K51.9 Ulcerative colitis, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
K51 Ulcerative colitis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
J33 Nasal polyp
0.000 0.000 1.000
N48 Other disorders of penis
0.000 0.000 1.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.000 1.000
E10.4 With neurological complications
0.000 0.000 1.000
E14.9 Without complications
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
E11.3 With ophthalmic complications
0.000 0.000 1.000
E14.3 With ophthalmic complications
0.000 0.000 1.000
D50-D53 Nutritional anaemias
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
Chapter XI Diseases of the digestive system
0.000 0.000 1.000
N40-N51 Diseases of male genital organs
0.000 0.000 1.000
K70-K77 Diseases of liver
0.000 0.000 1.000
Chapter II Neoplasms
0.000 0.000 1.000
D00-D09 In situ neoplasms
0.000 0.000 1.000
C21 Malignant neoplasm of anus and anal canal
0.000 0.000 1.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.000 1.000
N47 Redundant prepuce, phimosis and paraphimosis
0.000 0.000 1.000
J33.0 Polyp of nasal cavity
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
K90 Intestinal malabsorption
0.000 0.000 1.000
K75 Other inflammatory liver diseases
0.000 0.001 0.999
C15-C26 Malignant neoplasms of digestive organs
0.000 0.001 0.999
K75.4 Autoimmune hepatitis
0.000 0.001 0.999
M05 Seropositive rheumatoid arthritis
0.000 0.001 0.999
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.001 0.999
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.001 0.999
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.001 0.999
D64 Other anaemias
0.000 0.001 0.999
H36 Retinal disorders in diseases classified elsewhere
0.000 0.001 0.999
D50 Iron deficiency anaemia
0.000 0.001 0.999
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.001 0.999
D60-D64 Aplastic and other anaemias
0.000 0.001 0.999
K90-K93 Other diseases of the digestive system
0.000 0.001 0.999
E83.1 Disorders of iron metabolism
0.999 0.001 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.000 0.001 0.999
C21.0 Anus, unspecified
0.000 0.001 0.999
Chapter XIV Diseases of the genitourinary system
0.000 0.002 0.998
D07.1 Vulva
0.000 0.002 0.998
H30-H36 Disorders of choroid and retina
0.000 0.002 0.998
L90 Atrophic disorders of skin
0.000 0.002 0.998
D50.9 Iron deficiency anaemia, unspecified
0.000 0.002 0.998
N00-N08 Glomerular diseases
0.000 0.002 0.998
L90.0 Lichen sclerosus et atrophicus
0.000 0.002 0.998
Chapter VII Diseases of the eye and adnexa
0.000 0.003 0.997
J45 Asthma
0.000 0.003 0.997
N48.6 Balanitis xerotica obliterans
0.000 0.003 0.997
E20-E35 Disorders of other endocrine glands
0.000 0.004 0.996
D06 Carcinoma in situ of cervix uteri
0.000 0.004 0.996
K51.4 Pseudopolyposis of colon
0.996 0.004 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.000 0.004 0.996
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.004 0.996
E10.5 With peripheral circulatory complications
0.000 0.005 0.995
N48.1 Balanoposthitis
0.000 0.006 0.994
J40-J47 Chronic lower respiratory diseases
0.000 0.006 0.994
C21.1 Anal canal
0.000 0.007 0.993
H43-H45 Disorders of vitreous body and globe
0.000 0.007 0.993
D06.9 Cervix, unspecified
0.000 0.007 0.993
Chapter X Diseases of the respiratory system
0.000 0.007 0.993
E27 Other disorders of adrenal gland
0.000 0.008 0.992
H43 Disorders of vitreous body
0.000 0.008 0.992
D51 Vitamin B12 deficiency anaemia
0.000 0.009 0.991
E11.1 With ketoacidosis
0.000 0.009 0.991
N08 Glomerular disorders in diseases classified elsewhere
0.000 0.010 0.990
E27.1 Primary adrenocortical insufficiency
0.000 0.011 0.989
N05 Unspecified nephritic syndrome
0.000 0.012 0.988
K51.3 Ulcerative (chronic) rectosigmoiditis
0.987 0.013 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.000 0.014 0.986
L92.0 Granuloma annulare
0.000 0.015 0.985
H43.1 Vitreous haemorrhage
0.000 0.016 0.984
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.017 0.983
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.000 0.019 0.981
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.019 0.981
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.021 0.979
K51.2 Ulcerative (chronic) proctitis
0.976 0.024 0.000
J33.8 Other polyp of sinus
0.000 0.026 0.974
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.026 0.974
C20 Malignant neoplasm of rectum
0.000 0.027 0.973
E10.2 With renal complications
0.000 0.027 0.973
N48.0 Leukoplakia of penis
0.000 0.030 0.970
J46 Status asthmaticus
0.000 0.033 0.967
E10.0 With coma
0.000 0.035 0.965
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.037 0.963
Chapter IX Diseases of the circulatory system
0.000 0.040 0.960
I20-I25 Ischaemic heart diseases
0.000 0.041 0.959
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.041 0.959
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.000 0.041 0.959
E10.6 With other specified complications
0.000 0.044 0.956
E11.5 With peripheral circulatory complications
0.000 0.044 0.956
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.045 0.955
H34 Retinal vascular occlusions
0.000 0.049 0.951
E10.8 With unspecified complications
0.000 0.049 0.951
Chapter VI Diseases of the nervous system
0.000 0.049 0.951
C09 Malignant neoplasm of tonsil
0.000 0.049 0.951
E07 Other disorders of thyroid
0.000 0.050 0.950
L80 Vitiligo
0.000 0.053 0.947
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.000 0.055 0.945
L40-L45 Papulosquamous disorders
0.000 0.057 0.943
K51.5 Mucosal proctocolitis
0.940 0.060 0.000
K51.8 Other ulcerative colitis
0.940 0.060 0.000
N04 Nephrotic syndrome
0.000 0.060 0.940
I25 Chronic ischaemic heart disease
0.000 0.061 0.939
K72 Hepatic failure, not elsewhere classified
0.000 0.062 0.938
M06.3 Rheumatoid nodule
0.000 0.065 0.935
G63 Polyneuropathy in diseases classified elsewhere
0.000 0.065 0.935
N49.2 Inflammatory disorders of scrotum
0.000 0.067 0.933
K73 Chronic hepatitis, not elsewhere classified
0.000 0.071 0.929
C09.9 Tonsil, unspecified
0.000 0.071 0.929
K90.9 Intestinal malabsorption, unspecified
0.000 0.071 0.929
G63.2 Diabetic polyneuropathy
0.000 0.072 0.928
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.073 0.927
I20 Angina pectoris
0.000 0.074 0.926
E07.9 Disorder of thyroid, unspecified
0.000 0.074 0.926
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.075 0.925
L40 Psoriasis
0.000 0.075 0.925
H43.8 Other disorders of vitreous body
0.000 0.076 0.924
H34.8 Other retinal vascular occlusions
0.000 0.076 0.924
I24 Other acute ischaemic heart diseases
0.000 0.077 0.923
J30-J39 Other diseases of upper respiratory tract
0.000 0.077 0.923
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.000 0.078 0.922
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.078 0.922
J95-J99 Other diseases of the respiratory system
0.000 0.080 0.920
E11.2 With renal complications
0.000 0.081 0.919
L40.9 Psoriasis, unspecified
0.000 0.082 0.918
G35-G37 Demyelinating diseases of the central nervous system
0.848 0.083 0.069
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.083 0.917
I25.5 Ischaemic cardiomyopathy
0.000 0.084 0.916
E24 Cushing's syndrome
0.000 0.088 0.912
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.088 0.912
C91.1 Chronic lymphocytic leukaemia
0.000 0.091 0.909
K75.8 Other specified inflammatory liver diseases
0.000 0.093 0.907
D50.8 Other iron deficiency anaemias
0.000 0.093 0.907
I20.9 Angina pectoris, unspecified
0.000 0.095 0.905
E13 Other specified diabetes mellitus
0.000 0.096 0.904
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.098 0.902
N05.2 Diffuse membranous glomerulonephritis
0.000 0.099 0.901
E06 Thyroiditis
0.000 0.100 0.900
E16.1 Other hypoglycaemia
0.000 0.101 0.899
E21.0 Primary hyperparathyroidism
0.000 0.103 0.897
C91 Lymphoid leukaemia
0.000 0.103 0.897
K55-K64 Other diseases of intestines
0.000 0.104 0.896
I74 Arterial embolism and thrombosis
0.000 0.105 0.895
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.000 0.106 0.894
K60 Fissure and fistula of anal and rectal regions
0.000 0.109 0.891
M06.4 Inflammatory polyarthropathy
0.000 0.110 0.890
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.110 0.889
H43.3 Other vitreous opacities
0.000 0.112 0.888
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.112 0.888
K60.2 Anal fissure, unspecified
0.000 0.115 0.885
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.116 0.884
N05.1 Focal and segmental glomerular lesions
0.000 0.121 0.879
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.124 0.876
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.000 0.124 0.876
L10-L14 Bullous disorders
0.000 0.125 0.875
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.126 0.874
E50-E64 Other nutritional deficiencies
0.000 0.127 0.873
M45-M49 Spondylopathies
0.000 0.127 0.873
N04.9 Unspecified
0.000 0.127 0.873
E11.6 With other specified complications
0.000 0.127 0.873
E14.8 With unspecified complications
0.000 0.132 0.868
J45.0 Predominantly allergic asthma
0.000 0.134 0.866
D07.4 Penis
0.000 0.136 0.864
G50-G59 Nerve, nerve root and plexus disorders
0.000 0.136 0.864
K55 Vascular disorders of intestine
0.000 0.137 0.863
N48.4 Impotence of organic origin
0.000 0.141 0.859
G00-G09 Inflammatory diseases of the central nervous system
0.000 0.142 0.858
J86 Pyothorax
0.000 0.142 0.858
K72.0 Acute and subacute hepatic failure
0.000 0.143 0.857
E21.3 Hyperparathyroidism, unspecified
0.000 0.143 0.857
I20.0 Unstable angina
0.000 0.143 0.857
N48.2 Other inflammatory disorders of penis
0.000 0.144 0.856
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.000 0.144 0.856
D01 Carcinoma in situ of other and unspecified digestive organs
0.000 0.144 0.856
E14.1 With ketoacidosis
0.000 0.146 0.854
E06.3 Autoimmune thyroiditis
0.000 0.146 0.854
G70-G73 Diseases of myoneural junction and muscle
0.000 0.147 0.853
K55.2 Angiodysplasia of colon
0.000 0.147 0.853
E03.8 Other specified hypothyroidism
0.000 0.148 0.852
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.151 0.849
E53 Deficiency of other B group vitamins
0.000 0.152 0.848
G56.0 Carpal tunnel syndrome
0.000 0.157 0.843
G56 Mononeuropathies of upper limb
0.000 0.159 0.841
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.159 0.841
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.160 0.840
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.161 0.839
I77 Other disorders of arteries and arterioles
0.000 0.161 0.839
N05.8 Other
0.000 0.165 0.835
D04 Carcinoma in situ of skin
0.000 0.166 0.834
E53.8 Deficiency of other specified B group vitamins
0.000 0.167 0.833
I74.8 Embolism and thrombosis of other arteries
0.000 0.168 0.832
I74.5 Embolism and thrombosis of iliac artery
0.000 0.169 0.831
K51.0 Ulcerative (chronic) enterocolitis
0.830 0.170 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.171 0.829
E14.5 With peripheral circulatory complications
0.000 0.171 0.829
E13.9 Without complications
0.000 0.173 0.827
I25.2 Old myocardial infarction
0.000 0.173 0.827
J98 Other respiratory disorders
0.000 0.176 0.824
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.177 0.823
E14.6 With other specified complications
0.000 0.177 0.823
M14 Arthropathies in other diseases classified elsewhere
0.000 0.178 0.822
C22.9 Liver, unspecified
0.000 0.179 0.821
C23 Malignant neoplasm of gallbladder
0.000 0.179 0.821
J44 Other chronic obstructive pulmonary disease
0.000 0.181 0.819
G37 Other demyelinating diseases of central nervous system
0.796 0.183 0.020
N05.9 Unspecified
0.000 0.183 0.817
E20 Hypoparathyroidism
0.000 0.184 0.816
J86.0 Pyothorax with fistula
0.000 0.184 0.816
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.185 0.815
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.186 0.814
C04 Malignant neoplasm of floor of mouth
0.000 0.187 0.813
E27.2 Addisonian crisis
0.000 0.187 0.813
K60.0 Acute anal fissure
0.000 0.188 0.812
E11.0 With coma
0.000 0.192 0.808
J98.0 Diseases of bronchus, not elsewhere classified
0.000 0.194 0.806
G00 Bacterial meningitis, not elsewhere classified
0.000 0.197 0.803
C21.8 Overlapping lesion of rectum, anus and anal canal
0.000 0.198 0.802
G61 Inflammatory polyneuropathy
0.000 0.201 0.799
G60 Hereditary and idiopathic neuropathy
0.000 0.202 0.798
K74 Fibrosis and cirrhosis of liver
0.000 0.203 0.797
E14.4 With neurological complications
0.000 0.203 0.797
M48 Other spondylopathies
0.000 0.203 0.797
I10-I15 Hypertensive diseases
0.000 0.203 0.797
C07 Malignant neoplasm of parotid gland
0.000 0.204 0.796
E14.2 Withrenal complications
0.000 0.205 0.795
I25.1 Atherosclerotic heart disease
0.000 0.207 0.793
K60.1 Chronic anal fissure
0.000 0.207 0.793
K72.9 Hepatic failure, unspecified
0.000 0.209 0.791
G59 Mononeuropathy in diseases classified elsewhere
0.000 0.210 0.790
C22.1 Intrahepatic bile duct carcinoma
0.000 0.212 0.788
C10 Malignant neoplasm of oropharynx
0.000 0.215 0.785
M12 Other specific arthropathies
0.000 0.219 0.781
C12 Malignant neoplasm of pyriform sinus
0.000 0.220 0.780
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.221 0.779
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.221 0.779
E24.0 Pituitary-dependent Cushing's disease
0.000 0.222 0.778
K86 Other diseases of pancreas
0.000 0.222 0.778
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.223 0.777
D06.0 Endocervix
0.000 0.224 0.776
G72 Other myopathies
0.000 0.225 0.775
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.231 0.769
E24.9 Cushing's syndrome, unspecified
0.000 0.233 0.767
L13 Other bullous disorders
0.000 0.233 0.766
K57 Diverticular disease of intestine
0.000 0.236 0.764
G37.9 Demyelinating disease of central nervous system, unspecified
0.759 0.238 0.003
C02 Malignant neoplasm of other and unspecified parts of tongue
0.000 0.239 0.761
C11 Malignant neoplasm of nasopharynx
0.000 0.240 0.760
E05.8 Other thyrotoxicosis
0.000 0.241 0.758
I77.6 Arteritis, unspecified
0.000 0.243 0.757
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.243 0.757
K57.3 Diverticular disease of large intestine without perforation or abscess
0.000 0.243 0.757
L94 Other localised connective tissue disorders
0.000 0.244 0.756
N48.5 Ulcer of penis
0.000 0.245 0.755
M45 Ankylosing spondylitis
0.000 0.246 0.754
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.246 0.754
N48.9 Disorder of penis, unspecified
0.000 0.247 0.753
N04.1 Focal and segmental glomerular lesions
0.000 0.248 0.752
K86.3 Pseudocyst of pancreas
0.000 0.248 0.752
L95 Vasculitis limited to skin, not elsewhere classified
0.000 0.249 0.751
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.250 0.750
M06.8 Other specified rheumatoid arthritis
0.000 0.250 0.750
N51 Disorders of male genital organs in diseases classified elsewhere
0.000 0.250 0.749
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.251 0.749
J45.1 Nonallergic asthma
0.000 0.252 0.748
M48.0 Spinal stenosis
0.000 0.253 0.747
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.253 0.747
M20-M25 Other joint disorders
0.000 0.255 0.745
G00.1 Pneumococcal meningitis
0.000 0.255 0.745
C13 Malignant neoplasm of hypopharynx
0.000 0.255 0.745
G70 Myasthenia gravis and other myoneural disorders
0.000 0.256 0.743
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.259 0.741
M35 Other systemic involvement of connective tissue
0.000 0.261 0.739
M14.6 Neuropathic arthropathy
0.000 0.262 0.738
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.262 0.738
G59.0 Diabetic mononeuropathy
0.000 0.262 0.738
I10 Essential (primary) hypertension
0.000 0.264 0.736
M35.3 Polymyalgia rheumatica
0.000 0.264 0.736
M31 Other necrotising vasculopathies
0.000 0.264 0.736
D04.9 Skin, unspecified
0.000 0.268 0.732
D04.7 Skin of lower limb, including hip
0.000 0.269 0.731
M31.6 Other giant cell arteritis
0.000 0.269 0.731
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.270 0.730
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.271 0.729
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.271 0.729
M06.34 Rheumatoid nodule (Hand)
0.000 0.273 0.726
M10 Gout
0.000 0.274 0.726
K86.0 Alcohol-induced chronic pancreatitis
0.000 0.275 0.725
L12 Pemphigoid
0.000 0.275 0.725
M05.2 Rheumatoid vasculitis
0.000 0.276 0.724
L40.0 Psoriasis vulgaris
0.000 0.277 0.723
K73.9 Chronic hepatitis, unspecified
0.000 0.278 0.722
L40.1 Generalised pustular psoriasis
0.000 0.278 0.722
E21.2 Other hyperparathyroidism
0.000 0.279 0.721
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.279 0.721
K86.1 Other chronic pancreatitis
0.000 0.279 0.721
C60-C63 Malignant neoplasms of male genital organs
0.000 0.280 0.720
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.000 0.280 0.720
K55.8 Other vascular disorders of intestine
0.000 0.281 0.719
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.281 0.719
M49 Spondylopathies in diseases classified elsewhere
0.000 0.281 0.718
H30 Chorioretinal inflammation
0.000 0.282 0.718
G72.0 Drug-induced myopathy
0.000 0.282 0.718
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
K77 Liver disorders in diseases classified elsewhere
0.000 0.283 0.717
C21.2 Cloacogenic zone
0.000 0.283 0.717
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.000 0.283 0.717
L87 Transepidermal elimination disorders
0.000 0.283 0.717
L86 Keratoderma in diseases classified elsewhere
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
K90.3 Pancreatic steatorrhoea
0.000 0.283 0.717
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.283 0.717
K90.1 Tropical sprue
0.000 0.283 0.717
N05.7 Diffuse crescentic glomerulonephritis
0.000 0.283 0.717
K75.2 Nonspecific reactive hepatitis
0.000 0.283 0.717
K75.1 Phlebitis of portal vein
0.000 0.283 0.717
G51 Facial nerve disorders
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.284 0.716
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.284 0.716
M05.1 Rheumatoid lung disease
0.000 0.284 0.716
M05.0 Felty's syndrome
0.000 0.284 0.716
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.284 0.716
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.284 0.716
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.284 0.716
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.284 0.716
D64.4 Congenital dyserythropoietic anaemia
0.000 0.284 0.716
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.284 0.716
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.284 0.716
D64.0 Hereditary sideroblastic anaemia
0.000 0.284 0.716
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.284 0.716
D50.1 Sideropenic dysphagia
0.000 0.284 0.716
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.284 0.716
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.284 0.716
D07.6 Other and unspecified male genital organs
0.000 0.284 0.716
D07.3 Other and unspecified female genital organs
0.000 0.284 0.716
D07.0 Endometrium
0.000 0.284 0.716
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.284 0.716
L90.9 Atrophic disorder of skin, unspecified
0.000 0.284 0.716
L90.6 Striae atrophicae
0.000 0.284 0.716
L90.4 Acrodermatitis chronica atrophicans
0.000 0.284 0.716
L90.3 Atrophoderma of Pasini and Pierini
0.000 0.284 0.716
L90.2 Anetoderma of Jadassohn-Pellizzari
0.000 0.284 0.716
L90.1 Anetoderma of Schweninger-Buzzi
0.000 0.284 0.716
N07 Hereditary nephropathy, not elsewhere classified
0.000 0.284 0.716
N06 Isolated proteinuria with specified morphological lesion
0.000 0.284 0.716
N01 Rapidly progressive nephritic syndrome
0.000 0.284 0.716
N00 Acute nephritic syndrome
0.000 0.284 0.716
H31 Other disorders of choroid
0.000 0.285 0.715
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.285 0.715
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.286 0.714
E32 Diseases of thymus
0.000 0.286 0.714
E31 Polyglandular dysfunction
0.000 0.286 0.714
E30 Disorders of puberty, not elsewhere classified
0.000 0.286 0.714
D06.7 Other parts of cervix
0.000 0.286 0.714
D06.1 Exocervix
0.000 0.286 0.714
L92.2 Granuloma faciale [eosinophilic granuloma of skin]
0.000 0.286 0.714
L92.1 Necrobiosis lipoidica, not elsewhere classified
0.000 0.286 0.714
C91.9 Lymphoid leukaemia, unspecified
0.000 0.286 0.714
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.288 0.712
C01 Malignant neoplasm of base of tongue
0.000 0.288 0.712
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.288 0.712
D01.3 Anus and anal canal
0.000 0.289 0.711
E27.5 Adrenomedullary hyperfunction
0.000 0.289 0.711
E27.0 Other adrenocortical overactivity
0.000 0.289 0.711
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.289 0.711
D51.2 Transcobalamin II deficiency
0.000 0.289 0.711
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.289 0.711
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.000 0.290 0.710
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.290 0.710
N08.8 Glomerular disorders in other diseases classified elsewhere
0.000 0.290 0.709
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.000 0.290 0.709
N08.1 Glomerular disorders in neoplastic diseases
0.000 0.290 0.709
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.000 0.290 0.709
E21.4 Other specified disorders of parathyroid gland
0.000 0.291 0.708
N05.6 Dense deposit disease
0.000 0.292 0.708
N05.4 Diffuse endocapillary proliferative glomerulonephritis
0.000 0.292 0.708
N05.0 Minor glomerular abnormality
0.000 0.292 0.708
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.294 0.706
N44 Torsion of testis
0.000 0.294 0.706
E24.2 Drug-induced Cushing's syndrome
0.000 0.294 0.706
C91.0 Acute lymphoblastic leukaemia
0.000 0.296 0.704
N04.2 Diffuse membranous glomerulonephritis
0.000 0.296 0.704
G61.0 Guillain-Barre syndrome
0.000 0.298 0.702
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens
0.000 0.299 0.701
E11.8 With unspecified complications
0.000 0.300 0.700
H34.2 Other retinal artery occlusions
0.000 0.301 0.699
H35 Other retinal disorders
0.000 0.302 0.698
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.303 0.697
K71 Toxic liver disease
0.000 0.304 0.696
H43.0 Vitreous prolapse
0.000 0.304 0.696
H25-H28 Disorders of lens
0.000 0.304 0.696
E83 Disorders of mineral metabolism
0.695 0.305 0.000
M48.09 Spinal stenosis (Site unspecified)
0.000 0.306 0.694
D01.0 Colon
0.000 0.307 0.693
C04.9 Floor of mouth, unspecified
0.000 0.307 0.693
D53 Other nutritional anaemias
0.000 0.308 0.692
L13.0 Dermatitis herpetiformis
0.000 0.311 0.689
N49.9 Inflammatory disorder of unspecified male genital organ
0.000 0.312 0.688
N49.0 Inflammatory disorders of seminal vesicle
0.000 0.312 0.688
J44.9 Chronic obstructive pulmonary disease, unspecified
0.000 0.313 0.687
E20.9 Hypoparathyroidism, unspecified
0.000 0.313 0.687
L40.4 Guttate psoriasis
0.000 0.314 0.686
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.000 0.314 0.686
I25.6 Silent myocardial ischaemia
0.000 0.315 0.685
D07.2 Vagina
0.000 0.315 0.684
H43.2 Crystalline deposits in vitreous body
0.000 0.315 0.684
M06.1 Adult-onset Still's disease
0.000 0.316 0.684
H34.9 Retinal vascular occlusion, unspecified
0.000 0.317 0.683
H34.0 Transient retinal artery occlusion
0.000 0.318 0.682
C09.8 Overlapping lesion of tonsil
0.000 0.318 0.682
C09.1 Tonsillar pillar (anterior) (posterior)
0.000 0.318 0.682
C95 Leukaemia of unspecified cell type
0.000 0.318 0.682
I24.8 Other forms of acute ischaemic heart disease
0.000 0.319 0.681
J98.4 Other disorders of lung
0.000 0.319 0.681
E07.1 Dyshormogenetic goitre
0.000 0.319 0.681
E07.0 Hypersecretion of calcitonin
0.000 0.319 0.681
C08 Malignant neoplasm of other and unspecified major salivary glands
0.000 0.319 0.680
J98.6 Disorders of diaphragm
0.000 0.320 0.680
C09.0 Tonsillar fossa
0.000 0.320 0.680
E03.1 Congenital hypothyroidism without goitre
0.000 0.321 0.678
G64 Other disorders of peripheral nervous system
0.000 0.322 0.678
I22 Subsequent myocardial infarction
0.000 0.323 0.677
L44 Other papulosquamous disorders
0.000 0.324 0.676
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.324 0.676
E25 Adrenogenital disorders
0.000 0.325 0.675
K72.1 Chronic hepatic failure
0.000 0.325 0.675
J45.8 Mixed asthma
0.000 0.326 0.674
N04.8 Other
0.000 0.326 0.674
N04.7 Diffuse crescentic glomerulonephritis
0.000 0.326 0.674
N04.6 Dense deposit disease
0.000 0.326 0.674
N04.5 Diffuse mesangiocapillary glomerulonephritis
0.000 0.326 0.674
N04.4 Diffuse endocapillary proliferative glomerulonephritis
0.000 0.326 0.674
N04.3 Diffuse mesangial proliferative glomerulonephritis
0.000 0.326 0.674
N04.0 Minor glomerular abnormality
0.000 0.326 0.674
G60.0 Hereditary motor and sensory neuropathy
0.000 0.326 0.674
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.327 0.673
M11 Other crystal arthropathies
0.000 0.327 0.673
E13.3 With ophthalmic complications
0.000 0.328 0.672
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.330 0.670
M06.38 Rheumatoid nodule (Other)
0.000 0.330 0.670
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.330 0.670
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.330 0.670
M06.33 Rheumatoid nodule (Forearm)
0.000 0.330 0.670
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.330 0.670
G63.8 Polyneuropathy in other diseases classified elsewhere
0.000 0.330 0.670
G63.6 Polyneuropathy in other musculoskeletal disorders
0.000 0.330 0.670
G63.5 Polyneuropathy in systemic connective tissue disorders
0.000 0.330 0.670
G63.4 Polyneuropathy in nutritional deficiency
0.000 0.330 0.670
G63.3 Polyneuropathy in other endocrine and metabolic diseases
0.000 0.330 0.670
G63.1 Polyneuropathy in neoplastic disease
0.000 0.330 0.670
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere
0.000 0.330 0.670
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.331 0.669

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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