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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant cluster associations

Hospitalization Episode Statistics (HES)

Cluster X0003
log Bayes Factor = 195.6
contains 8 variants:
rs10797386
lBF = 13.245
Chr 1 : 3,168,280
rs114080907
lBF = 15.186
Chr 1 : 21,077,245
rs113984483
lBF = 13.969
Chr 2 : 35,302,577
rs78685710
lBF = 14.727
Chr 3 : 189,149,244
rs73214037
lBF = 13.659
Chr 3 : 197,395,630
rs114187425
lBF = 13.472
Chr 4 : 127,057,914
rs362885
lBF = 8.920
Chr 6 : 146,676,552
rs74759033
lBF = 10.867
Chr 9 : 127,676,918
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E86 Volume depletion
1.000 0.000 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
1.000 0.000 0.000
K70 Alcoholic liver disease
1.000 0.000 0.000
N18 Chronic renal failure
1.000 0.000 0.000
A30-A49 Other bacterial diseases
1.000 0.000 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
1.000 0.000 0.000
E20-E35 Disorders of other endocrine glands
1.000 0.000 0.000
E70-E90 Metabolic disorders
1.000 0.000 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
1.000 0.000 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
1.000 0.000 0.000
K70-K77 Diseases of liver
1.000 0.000 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
1.000 0.000 0.000
N17-N19 Renal failure
1.000 0.000 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
1.000 0.000 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
1.000 0.000 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
1.000 0.000 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Z93 Artificial opening status
1.000 0.000 0.000
I60-I69 Cerebrovascular diseases
1.000 0.000 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
1.000 0.000 0.000
Chapter XXII Codes for special purposes
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
I85 Oesophageal varices
1.000 0.000 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
K83 Other diseases of biliary tract
1.000 0.000 0.000
I95-I99 Other and unspecified disorders of the circulatory system
1.000 0.000 0.000
N18.9 Chronic renal failure, unspecified
1.000 0.000 0.000
N18.3 Chronic kidney disease, stage 3
1.000 0.000 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
1.000 0.000 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
A41 Other septicaemia
1.000 0.000 0.000
I67 Other cerebrovascular diseases
1.000 0.000 0.000
K83.1 Obstruction of bile duct
1.000 0.000 0.000
U80 Agent resistant to penicillin and related antibiotics
1.000 0.000 0.000
B95-B98 Bacterial, viral and other infectious agents
0.999 0.001 0.000
N10-N16 Renal tubulo-interstitial diseases
0.999 0.001 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.999 0.001 0.000
J09-J18 Influenza and pneumonia
0.999 0.001 0.000
N25-N29 Other disorders of kidney and ureter
0.999 0.001 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.999 0.001 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.999 0.001 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.999 0.001 0.000
I95 Hypotension
0.999 0.001 0.000
K82 Other diseases of gallbladder
0.999 0.001 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.999 0.001 0.000
Z94 Transplanted organ and tissue status
0.999 0.001 0.000
I85.9 Oesophageal varices without bleeding
0.999 0.001 0.000
S60-S69 Injuries to the wrist and hand
0.999 0.001 0.000
A49 Bacterial infection of unspecified site
0.999 0.001 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.998 0.002 0.000
K70.9 Alcoholic liver disease, unspecified
0.998 0.002 0.000
I30-I52 Other forms of heart disease
0.998 0.002 0.000
I82 Other venous embolism and thrombosis
0.998 0.002 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.998 0.002 0.000
I67.1 Cerebral aneurysm, nonruptured
0.998 0.002 0.000
O30 Multiple gestation
0.998 0.002 0.000
N13 Obstructive and reflux uropathy
0.998 0.002 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.997 0.003 0.000
A49.8 Other bacterial infections of unspecified site
0.997 0.003 0.000
E87.5 Hyperkalaemia
0.997 0.003 0.000
Chapter V Mental and behavioural disorders
0.997 0.003 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.997 0.003 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.997 0.003 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.997 0.003 0.000
I05-I09 Chronic rheumatic heart diseases
0.997 0.003 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.997 0.003 0.000
T86 Failure and rejection of transplanted organs and tissues
0.997 0.003 0.000
Z49 Care involving dialysis
0.997 0.003 0.000
N28.8 Other specified disorders of kidney and ureter
0.996 0.004 0.000
I44 Atrioventricular and left bundle-branch block
0.996 0.004 0.000
Z99.2 Dependence on renal dialysis
0.996 0.004 0.000
O30.0 Twin pregnancy
0.996 0.004 0.000
N17 Acute renal failure
0.996 0.004 0.000
K90-K93 Other diseases of the digestive system
0.996 0.004 0.000
O60-O75 Complications of labour and delivery
0.996 0.004 0.000
K65-K67 Diseases of peritoneum
0.996 0.004 0.000
G62 Other polyneuropathies
0.996 0.004 0.000
S64 Injury of nerves at wrist and hand level
0.996 0.004 0.000
I71 Aortic aneurysm and dissection
0.996 0.004 0.000
M80-M85 Disorders of bone density and structure
0.996 0.004 0.000
Z94.0 Kidney transplant status
0.996 0.004 0.000
D80-D89 Certain disorders involving the immune mechanism
0.996 0.004 0.000
U80.1 Methicillin resistant agent
0.995 0.005 0.000
I44.0 Atrioventricular block, first degree
0.995 0.005 0.000
B25-B34 Other viral diseases
0.995 0.005 0.000
Z93.1 Gastrostomy status
0.995 0.005 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.995 0.005 0.000
Z96.0 Presence of urogenital implants
0.994 0.006 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.994 0.006 0.000
I70 Atherosclerosis
0.994 0.006 0.000
G90-G99 Other disorders of the nervous system
0.994 0.006 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.994 0.006 0.000
B15-B19 Viral hepatitis
0.994 0.006 0.000
K70.3 Alcoholic cirrhosis of liver
0.994 0.006 0.000
N00-N08 Glomerular diseases
0.994 0.006 0.000
E87.7 Fluid overload
0.993 0.007 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.993 0.007 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.993 0.007 0.000
M24 Other specific joint derangements
0.993 0.007 0.000
K65 Peritonitis
0.992 0.008 0.000
K86 Other diseases of pancreas
0.992 0.008 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.992 0.008 0.000
K72 Hepatic failure, not elsewhere classified
0.992 0.008 0.000
Z46 Fitting and adjustment of other devices
0.992 0.008 0.000
Z96 Presence of other functional implants
0.992 0.008 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.991 0.009 0.000
K82.8 Other specified diseases of gallbladder
0.991 0.009 0.000
D86 Sarcoidosis
0.991 0.009 0.000
Chapter VIII Diseases of the ear and mastoid process
0.991 0.009 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.991 0.009 0.000
S20-S29 Injuries to the thorax
0.990 0.010 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.990 0.010 0.000
Z39 Postpartum care and examination
0.990 0.010 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.990 0.010 0.000
I67.2 Cerebral atherosclerosis
0.989 0.011 0.000
C09 Malignant neoplasm of tonsil
0.989 0.011 0.000
Z35 Supervision of high-risk pregnancy
0.989 0.011 0.000
M60-M63 Disorders of muscles
0.989 0.011 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.988 0.012 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.988 0.012 0.000
D68 Other coagulation defects
0.987 0.013 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.987 0.013 0.000
B34 Viral infection of unspecified site
0.987 0.013 0.000
O16 Unspecified maternal hypertension
0.987 0.013 0.000
M15-M19 Arthrosis
0.986 0.014 0.000
I81 Portal vein thrombosis
0.986 0.014 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.986 0.014 0.000
Z39.0 Care and examination immediately after delivery
0.986 0.014 0.000
I85.0 Oesophageal varices with bleeding
0.984 0.016 0.000
K65.0 Acute peritonitis
0.984 0.016 0.000
N17.9 Acute renal failure, unspecified
0.984 0.016 0.000
S90-S99 Injuries to the ankle and foot
0.984 0.016 0.000
Q60-Q64 Congenital malformations of the urinary system
0.984 0.016 0.000
K92 Other diseases of digestive system
0.983 0.017 0.000
G62.9 Polyneuropathy, unspecified
0.983 0.017 0.000
T86.1 Kidney transplant failure and rejection
0.983 0.017 0.000
I70.0 Atherosclerosis of aorta
0.983 0.017 0.000
K92.1 Melaena
0.983 0.017 0.000
J90-J94 Other diseases of pleura
0.983 0.017 0.000
C09.9 Tonsil, unspecified
0.983 0.017 0.000
Z99.1 Dependence on respirator
0.982 0.018 0.000
I82.8 Embolism and thrombosis of other specified veins
0.982 0.018 0.000
T51 Toxic effect of alcohol
0.982 0.018 0.000
J93 Pneumothorax
0.982 0.018 0.000
Z37 Outcome of delivery
0.982 0.018 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.981 0.019 0.000
M62 Other disorders of muscle
0.981 0.019 0.000
Z49.0 Preparatory care for dialysis
0.981 0.019 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.981 0.019 0.000
M91-M94 Chondropathies
0.980 0.020 0.000
E27 Other disorders of adrenal gland
0.980 0.020 0.000
I74 Arterial embolism and thrombosis
0.980 0.020 0.000
S64.4 Injury of digital nerve of other finger
0.979 0.021 0.000
K86.9 Disease of pancreas, unspecified
0.979 0.021 0.000
K72.9 Hepatic failure, unspecified
0.979 0.021 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.978 0.022 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.978 0.022 0.000
B34.9 Viral infection, unspecified
0.978 0.022 0.000
J81 Pulmonary oedema
0.977 0.023 0.000
I95.1 Orthostatic hypotension
0.977 0.023 0.000
M62.8 Other specified disorders of muscle
0.976 0.024 0.000
I70.00 Atherosclerosis of aorta (without gangrene)
0.976 0.024 0.000
M84 Disorders of continuity of bone
0.976 0.024 0.000
Z37.2 Twins, both liveborn
0.975 0.025 0.000
N18.0 End-stage renal disease
0.975 0.025 0.000
O85-O92 Complications predominantly related to the puerperium
0.975 0.025 0.000
F30-F39 Mood [affective] disorders
0.974 0.026 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.974 0.026 0.000
Z93.0 Tracheostomy status
0.973 0.027 0.000
J93.9 Pneumothorax, unspecified
0.973 0.027 0.000
K70.1 Alcoholic hepatitis
0.973 0.027 0.000
O23 Infections of genito-urinary tract in pregnancy
0.973 0.027 0.000
N19 Unspecified renal failure
0.973 0.027 0.000
E28 Ovarian dysfunction
0.973 0.027 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.972 0.028 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.972 0.028 0.000
C71 Malignant neoplasm of brain
0.972 0.028 0.000
M70-M79 Other soft tissue disorders
0.971 0.029 0.000
I05 Rheumatic mitral valve diseases
0.971 0.029 0.000
Z56 Problems related to employment and unemployment
0.970 0.030 0.000
J84 Other interstitial pulmonary diseases
0.970 0.030 0.000
E21.0 Primary hyperparathyroidism
0.969 0.031 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.968 0.032 0.000
G62.8 Other specified polyneuropathies
0.968 0.032 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.967 0.033 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.967 0.033 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.965 0.035 0.000
Z31 Procreative management
0.965 0.035 0.000
Z33 Pregnant state, incidental
0.965 0.035 0.000
Z93.6 Other artificial openings of urinary tract status
0.965 0.035 0.000
H80-H83 Diseases of inner ear
0.964 0.036 0.000
Z49.2 Other dialysis
0.964 0.036 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.964 0.036 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.964 0.036 0.000
N18.5 Chronic kidney disease, stage 5
0.963 0.037 0.000
D38.1 Trachea, bronchus and lung
0.963 0.037 0.000
I95.8 Other hypotension
0.962 0.038 0.000
T51.0 Ethanol
0.962 0.038 0.000
I60 Subarachnoid haemorrhage
0.962 0.038 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.961 0.039 0.000
F33 Recurrent depressive disorder
0.960 0.040 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.960 0.040 0.000
Z29 Need for other prophylactic measures
0.959 0.041 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.959 0.041 0.000
I08 Multiple valve diseases
0.959 0.041 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.959 0.041 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.958 0.042 0.000
S10-S19 Injuries to the neck
0.958 0.042 0.000
I74.5 Embolism and thrombosis of iliac artery
0.958 0.042 0.000
Z93.3 Colostomy status
0.957 0.043 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.957 0.043 0.000
E89.0 Postprocedural hypothyroidism
0.957 0.043 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.956 0.044 0.000
E83 Disorders of mineral metabolism
0.956 0.044 0.000
Y43 Primarily systemic agents
0.956 0.044 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.954 0.046 0.000
K65.8 Other peritonitis
0.953 0.047 0.000
T66-T78 Other and unspecified effects of external causes
0.953 0.047 0.000
M25 Other joint disorders, not elsewhere classified
0.953 0.047 0.000
K50-K52 Noninfective enteritis and colitis
0.953 0.047 0.000
M85 Other disorders of bone density and structure
0.953 0.047 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.953 0.047 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.952 0.048 0.000
J10 Influenza due to identified influenza virus
0.952 0.048 0.000
U80.0 Penicillin resistant agent
0.951 0.049 0.000
K74 Fibrosis and cirrhosis of liver
0.951 0.049 0.000
B18 Chronic viral hepatitis
0.950 0.050 0.000
O32.8 Maternal care for other malpresentation of foetus
0.950 0.050 0.000
K70.4 Alcoholic hepatic failure
0.949 0.051 0.000
O21 Excessive vomiting in pregnancy
0.949 0.051 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.948 0.052 0.000
I95.9 Hypotension, unspecified
0.948 0.052 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.948 0.052 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.948 0.052 0.000
I46 Cardiac arrest
0.947 0.053 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.947 0.053 0.000
D48.6 Breast
0.946 0.054 0.000
K52 Other non-infective gastro-enteritis and colitis
0.945 0.055 0.000
E28.2 Polycystic ovarian syndrome
0.945 0.055 0.000
E29 Testicular dysfunction
0.945 0.055 0.000
E21.3 Hyperparathyroidism, unspecified
0.944 0.056 0.000
I63 Cerebral infarction
0.944 0.056 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.944 0.056 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.944 0.056 0.000
Z46.2 Fitting and adjustment of other devices related to nervous system and special senses
0.943 0.057 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.942 0.058 0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)
0.941 0.059 0.000
E89.3 Postprocedural hypopituitarism
0.941 0.059 0.000
M18 Arthrosis of first carpometacarpal joint
0.940 0.060 0.000
M31 Other necrotising vasculopathies
0.940 0.060 0.000
D86.9 Sarcoidosis, unspecified
0.940 0.060 0.000
Z89 Acquired absence of limb
0.940 0.060 0.000
B35-B49 Mycoses
0.940 0.060 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.939 0.061 0.000
E87.0 Hyperosmolality and hypernatraemia
0.939 0.061 0.000
D37.1 Stomach
0.939 0.061 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.938 0.062 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.938 0.062 0.000
Y42.7 Androgens and anabolic congeners
0.937 0.063 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.937 0.063 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.937 0.063 0.000
K86.0 Alcohol-induced chronic pancreatitis
0.937 0.063 0.000
D46 Myelodysplastic syndromes
0.937 0.063 0.000
Q80-Q89 Other congenital malformations
0.937 0.063 0.000
I86 Varicose veins of other sites
0.936 0.064 0.000
D37.7 Other digestive organs
0.936 0.064 0.000
J18 Pneumonia, organism unspecified
0.936 0.064 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.936 0.064 0.000
G96 Other disorders of central nervous system
0.936 0.064 0.000
A40 Streptococcal septicaemia
0.935 0.065 0.000
E34 Other endocrine disorders
0.935 0.065 0.000
S27 Injury of other and unspecified intrathoracic organs
0.935 0.065 0.000
Z35.5 Supervision of elderly primigravida
0.935 0.065 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.934 0.066 0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.934 0.066 0.000
Q61 Cystic kidney disease
0.934 0.066 0.000
N17.0 Acute renal failure with tubular necrosis
0.934 0.066 0.000
H60-H62 Diseases of external ear
0.933 0.067 0.000
I72 Other aneurysm
0.933 0.067 0.000
N99-N99 Other disorders of the genitourinary system
0.933 0.067 0.000
J18.0 Bronchopneumonia, unspecified
0.933 0.067 0.000
E83.4 Disorders of magnesium metabolism
0.931 0.069 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.931 0.069 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.931 0.069 0.000
M22 Disorders of patella
0.931 0.069 0.000
O23.4 Unspecified infection of urinary tract in pregnancy
0.931 0.069 0.000
V20-V29 Motorcycle rider injured in transport accident
0.930 0.069 0.000
Y44 Agents primarily affecting blood constituents
0.930 0.070 0.000
G90 Disorders of autonomic nervous system
0.930 0.070 0.000
H81 Disorders of vestibular function
0.930 0.070 0.000
M19 Other arthrosis
0.929 0.071 0.000
U80.8 Agent resistant to other penicillin-related antibiotic
0.929 0.071 0.000
T78 Adverse effects, not elsewhere classified
0.929 0.071 0.000
O64.1 Obstructed labour due to breech presentation
0.929 0.071 0.000
O90 Complications of the puerperium, not elsewhere classified
0.929 0.071 0.000
E26 Hyperaldosteronism
0.928 0.072 0.000
S69 Other and unspecified injuries of wrist and hand
0.928 0.072 0.000
K73 Chronic hepatitis, not elsewhere classified
0.928 0.072 0.000
Y52 Agents primarily affecting the cardiovascular system
0.928 0.072 0.000
K40-K46 Hernia
0.927 0.073 0.000
D86.0 Sarcoidosis of lung
0.927 0.073 0.000
E89.2 Postprocedural hypoparathyroidism
0.924 0.076 0.000
K82.1 Hydrops of gallbladder
0.924 0.076 0.000
A41.8 Other specified septicaemia
0.924 0.076 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.923 0.077 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.922 0.078 0.000
M19.0 Primary arthrosis of other joints
0.922 0.078 0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head
0.922 0.078 0.000
Z58 Problems related to physical environment
0.922 0.078 0.000
N03 Chronic nephritic syndrome
0.922 0.078 0.000
Z46.5 Fitting and adjustment of ileostomy and other intestinal appliances
0.921 0.079 0.000
N18.2 Chronic kidney disease, stage 2
0.921 0.079 0.000
C71.2 Temporal lobe
0.920 0.080 0.000
U88 Agent resistant to multiple antibiotics
0.920 0.080 0.000
J14 Pneumonia due to Haemophilus influenzae
0.920 0.080 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.920 0.080 0.000
S70-S79 Injuries to the hip and thigh
0.919 0.081 0.000
O12.1 Gestational proteinuria
0.919 0.081 0.000
J10.1 Influenza with other respiratory manifestations, influenza virus identified
0.918 0.082 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.918 0.082 0.000
M62.80 Other specified disorders of muscle (Multiple sites)
0.918 0.082 0.000
N76 Other inflammation of vagina and vulva
0.918 0.082 0.000
Z43 Attention to artificial openings
0.918 0.082 0.000
I46.9 Cardiac arrest, unspecified
0.918 0.082 0.000
T23 Burn and corrosion of wrist and hand
0.918 0.082 0.000
O32.1 Maternal care for breech presentation
0.917 0.083 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.917 0.083 0.000
C81 Hodgkin's disease
0.916 0.084 0.000
M84.0 Malunion of fracture
0.916 0.084 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.916 0.084 0.000
A63.0 Anogenital (venereal) warts
0.914 0.086 0.000
I08.0 Disorders of both mitral and aortic valves
0.914 0.086 0.000
N25 Disorders resulting from impaired renal tubular function
0.914 0.086 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.913 0.087 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.913 0.087 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.912 0.088 0.000
I36 Nonrheumatic tricuspid valve disorders
0.911 0.088 0.000
I61 Intracerebral haemorrhage
0.911 0.089 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.911 0.089 0.000
J93.1 Other spontaneous pneumothorax
0.911 0.089 0.000
K52.0 Gastro-enteritis and colitis due to radiation
0.911 0.089 0.000
Y43.1 Antineoplastic antimetabolites
0.910 0.090 0.000
Q61.3 Polycystic kidney, unspecified
0.910 0.090 0.000
Q50-Q56 Congenital malformations of genital organs
0.910 0.090 0.000
I82.9 Embolism and thrombosis of unspecified vein
0.910 0.090 0.000
O32.0 Maternal care for unstable lie
0.910 0.090 0.000
T20 Burn and corrosion of head and neck
0.910 0.090 0.000
D86.8 Sarcoidosis of other and combined sites
0.909 0.091 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.909 0.091 0.000
I82.2 Embolism and thrombosis of vena cava
0.909 0.091 0.000
M31.6 Other giant cell arteritis
0.909 0.091 0.000
T91 Sequelae of injuries of neck and trunk
0.909 0.091 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.909 0.091 0.000
S22.4 Multiple fractures of ribs
0.908 0.092 0.000
C32 Malignant neoplasm of larynx
0.908 0.092 0.000
H61 Other disorders of external ear
0.907 0.093 0.000
K82.9 Disease of gallbladder, unspecified
0.907 0.093 0.000
K74.0 Hepatic fibrosis
0.906 0.094 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.906 0.094 0.000
N13.8 Other obstructive and reflux uropathy
0.906 0.094 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.905 0.095 0.000
E29.1 Testicular hypofunction
0.905 0.095 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.904 0.096 0.000
M94 Other disorders of cartilage
0.904 0.096 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.903 0.097 0.000
Y40 Systemic antibiotics
0.902 0.098 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.901 0.099 0.000
O62 Abnormalities of forces of labour
0.901 0.099 0.000
F10.4 Withdrawal state with delirium
0.900 0.100 0.000
E10-E14 Diabetes mellitus
0.900 0.100 0.000
Z81 Family history of mental and behavioural disorders
0.900 0.100 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.899 0.101 0.000
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history
0.899 0.101 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.899 0.101 0.000
S32 Fracture of lumbar spine and pelvis
0.899 0.101 0.000
S22.40 Multiple fractures of ribs (closed)
0.898 0.102 0.000
O21.0 Mild hyperemesis gravidarum
0.897 0.103 0.000
X60-X84 Intentional self-harm
0.897 0.103 0.000
Z56.6 Other physical and mental strain related to work
0.897 0.103 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.897 0.103 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.897 0.103 0.000
Z31.2 In vitro fertilisation
0.897 0.103 0.000
Z54 Convalescence
0.896 0.104 0.000
K46 Unspecified abdominal hernia
0.896 0.104 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.896 0.104 0.000
Y57 Other and unspecified drugs and medicaments
0.895 0.105 0.000
Z46.6 Fitting and adjustment of urinary device
0.895 0.105 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.894 0.106 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.894 0.106 0.000
T86.8 Failure and rejection of other transplanted organs and tissues
0.894 0.106 0.000
T90 Sequelae of injuries of head
0.894 0.106 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.894 0.106 0.000
D48.0 Bone and articular cartilage
0.893 0.107 0.000
S99 Other and unspecified injuries of ankle and foot
0.893 0.107 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.893 0.107 0.000
D48.7 Other specified sites
0.893 0.107 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.893 0.107 0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)
0.893 0.107 0.000
B02 Zoster [herpes zoster]
0.892 0.108 0.000
G96.0 Cerebrospinal fluid leak
0.892 0.108 0.000
D80 Immunodeficiency with predominantly antibody defects
0.892 0.108 0.000
M21 Other acquired deformities of limbs
0.892 0.108 0.000
Chapter VII Diseases of the eye and adnexa
0.892 0.108 0.000
S29 Other and unspecified injuries of thorax
0.891 0.109 0.000
Z89.4 Acquired absence of foot and ankle
0.891 0.109 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.889 0.111 0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
0.889 0.111 0.000
I05.0 Mitral stenosis
0.889 0.111 0.000
J84.9 Interstitial pulmonary disease, unspecified
0.889 0.111 0.000
K90 Intestinal malabsorption
0.888 0.112 0.000
M77 Other enthesopathies
0.887 0.113 0.000
I35 Nonrheumatic aortic valve disorders
0.887 0.113 0.000
B16 Acute hepatitis B
0.887 0.113 0.000
Z52 Donors of organs and tissues
0.887 0.113 0.000
G70-G73 Diseases of myoneural junction and muscle
0.886 0.114 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.885 0.115 0.000
Q43 Other congenital malformations of intestine
0.885 0.115 0.000
K82.2 Perforation of gallbladder
0.885 0.115 0.000
Z29.1 Prophylactic immunotherapy
0.885 0.115 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.885 0.115 0.000
Z84 Family history of other conditions
0.885 0.115 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.884 0.116 0.000
B00 Herpesviral [herpes simplex] infections
0.884 0.116 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.884 0.116 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.884 0.116 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.884 0.116 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.883 0.117 0.000
J95-J99 Other diseases of the respiratory system
0.883 0.117 0.000
O43 Placental disorders
0.883 0.117 0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more
0.883 0.117 0.000
H18 Other disorders of cornea
0.882 0.118 0.000
T82.3 Mechanical complication of other vascular grafts
0.882 0.118 0.000
W00-W19 Falls
0.882 0.118 0.000
D68.5 Primary Thrombophilia
0.882 0.118 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.882 0.118 0.000
W50-W64 Exposure to animate mechanical forces
0.881 0.119 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.881 0.119 0.000
I77 Other disorders of arteries and arterioles
0.881 0.119 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.881 0.119 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.881 0.119 0.000
H80 Otosclerosis
0.881 0.119 0.000
Y44.2 Anticoagulants
0.880 0.120 0.000
Z56.0 Unemployment, unspecified
0.880 0.120 0.000
O90.8 Other complications of the puerperium, not elsewhere classified
0.880 0.120 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.879 0.121 0.000
S64.2 Injury of radial nerve at wrist and hand level
0.879 0.121 0.000
K52.1 Toxic gastro-enteritis and colitis
0.879 0.121 0.000
C71.9 Brain, unspecified
0.879 0.121 0.000
K41 Femoral hernia
0.878 0.121 0.000
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status
0.878 0.122 0.000
Z94.7 Corneal transplant status
0.878 0.122 0.000
I87 Other disorders of veins
0.877 0.123 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.877 0.123 0.000
M62.89 Other specified disorders of muscle (Site unspecified)
0.877 0.123 0.000
M22.2 Patellofemoral disorders
0.877 0.123 0.000
C32.9 Larynx, unspecified
0.877 0.123 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.876 0.124 0.000
E26.0 Primary hyperaldosteronism
0.876 0.124 0.000
I62 Other nontraumatic intracranial haemorrhage
0.876 0.124 0.000
O14.9 Preeclampsia, unspecified
0.876 0.124 0.000
D75 Other diseases of blood and blood-forming organs
0.875 0.125 0.000
O75.8 Other specified complications of labour and delivery
0.875 0.125 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.873 0.127 0.000
K70.0 Alcoholic fatty liver
0.873 0.127 0.000
E88 Other metabolic disorders
0.873 0.127 0.000
M19.03 Primary arthrosis of other joints (Forearm)
0.872 0.128 0.000
O12.0 Gestational oedema
0.872 0.128 0.000
J94 Other pleural conditions
0.872 0.128 0.000
I35.0 Aortic (valve) stenosis
0.871 0.129 0.000
M93 Other osteochondropathies
0.871 0.129 0.000
Z58.1 Exposure to air pollution
0.871 0.129 0.000
M76 Enthesopathies of lower limb, excluding foot
0.871 0.129 0.000
K72.0 Acute and subacute hepatic failure
0.871 0.129 0.000
Z49.1 Extracorporeal dialysis
0.871 0.129 0.000
N03.9 Unspecified
0.871 0.129 0.000
I86.8 Varicose veins of other specified sites
0.870 0.130 0.000
S64.0 Injury of ulnar nerve at wrist and hand level
0.870 0.130 0.000
B18.2 Chronic viral hepatitis C
0.870 0.130 0.000
D37.6 Liver, gallbladder and bile ducts
0.869 0.131 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.868 0.132 0.000
M19.04 Primary arthrosis of other joints (Hand)
0.868 0.132 0.000
I44.2 Atrioventricular block, complete
0.868 0.132 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.867 0.133 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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