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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78685710
log Bayes Factor = 14.7268
Chromosome 3   position 189,149,244  (GRCh37) Explore rs78685710 on Ensembl!
Variant rs78685710 is part of Cluster X0003

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
N17-N19 Renal failure
0.999 0.001 0.000
I20 Angina pectoris
0.999 0.001 0.000
Chapter I Certain infectious and parasitic diseases
0.998 0.002 0.000
N18 Chronic renal failure
0.998 0.002 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.997 0.003 0.000
B95-B98 Bacterial, viral and other infectious agents
0.995 0.005 0.000
I50 Heart failure
0.993 0.007 0.000
N18.9 Chronic renal failure, unspecified
0.990 0.010 0.000
Chapter XI Diseases of the digestive system
0.989 0.011 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.989 0.011 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.988 0.012 0.000
I50.0 Congestive heart failure
0.987 0.013 0.000
I20.0 Unstable angina
0.977 0.023 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.977 0.023 0.000
E20-E35 Disorders of other endocrine glands
0.977 0.023 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.968 0.032 0.000
K50-K52 Noninfective enteritis and colitis
0.964 0.036 0.000
K70-K77 Diseases of liver
0.962 0.038 0.000
O60-O75 Complications of labour and delivery
0.959 0.041 0.000
N18.3 Chronic kidney disease, stage 3
0.957 0.043 0.000
Chapter V Mental and behavioural disorders
0.957 0.043 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.956 0.044 0.000
I20.9 Angina pectoris, unspecified
0.955 0.045 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.953 0.047 0.000
I25 Chronic ischaemic heart disease
0.951 0.049 0.000
D50-D53 Nutritional anaemias
0.951 0.049 0.000
K70 Alcoholic liver disease
0.945 0.055 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.938 0.062 0.000
D80-D89 Certain disorders involving the immune mechanism
0.936 0.064 0.000
Chapter II Neoplasms
0.936 0.064 0.000
D10-D36 Benign neoplasms
0.934 0.066 0.000
I20.8 Other forms of angina pectoris
0.932 0.068 0.000
E27 Other disorders of adrenal gland
0.931 0.069 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.931 0.069 0.000
K86 Other diseases of pancreas
0.928 0.072 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.928 0.072 0.000
K51 Ulcerative colitis
0.925 0.075 0.000
Chapter XX External causes of morbidity and mortality
0.920 0.080 0.000
I35 Nonrheumatic aortic valve disorders
0.919 0.081 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.913 0.087 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.911 0.089 0.000
O63 Long labour
0.910 0.090 0.000
N10-N16 Renal tubulo-interstitial diseases
0.909 0.091 0.000
N00-N08 Glomerular diseases
0.909 0.091 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.907 0.093 0.000
D50 Iron deficiency anaemia
0.906 0.094 0.000
K70.9 Alcoholic liver disease, unspecified
0.906 0.094 0.000
E70-E90 Metabolic disorders
0.905 0.095 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.902 0.098 0.000
D24 Benign neoplasm of breast
0.900 0.100 0.000
I45 Other conduction disorders
0.898 0.102 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.896 0.104 0.000
K90-K93 Other diseases of the digestive system
0.896 0.104 0.000
N17 Acute renal failure
0.894 0.106 0.000
I44 Atrioventricular and left bundle-branch block
0.894 0.106 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.888 0.112 0.000
D86 Sarcoidosis
0.887 0.113 0.000
D23 Other benign neoplasms of skin
0.884 0.116 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.883 0.117 0.000
B15-B19 Viral hepatitis
0.879 0.121 0.000
N25-N29 Other disorders of kidney and ureter
0.877 0.123 0.000
I46 Cardiac arrest
0.876 0.124 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.864 0.136 0.000
I71 Aortic aneurysm and dissection
0.863 0.137 0.000
D50.9 Iron deficiency anaemia, unspecified
0.861 0.139 0.000
F41 Other anxiety disorders
0.858 0.142 0.000
I35.0 Aortic (valve) stenosis
0.856 0.144 0.000
O42 Premature rupture of membranes
0.856 0.144 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.856 0.144 0.000
E27.1 Primary adrenocortical insufficiency
0.856 0.144 0.000
E28 Ovarian dysfunction
0.855 0.145 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.855 0.145 0.000
I20.1 Angina pectoris with documented spasm
0.855 0.145 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.854 0.146 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.853 0.147 0.000
N19 Unspecified renal failure
0.849 0.151 0.000
O63.1 Prolonged second stage (of labour)
0.847 0.153 0.000
D13.1 Stomach
0.847 0.153 0.000
Y40 Systemic antibiotics
0.847 0.153 0.000
T66-T78 Other and unspecified effects of external causes
0.845 0.155 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.844 0.156 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.842 0.158 0.000
I72 Other aneurysm
0.841 0.158 0.000
I22 Subsequent myocardial infarction
0.840 0.160 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.839 0.161 0.000
I50.9 Heart failure, unspecified
0.836 0.164 0.000
I34 Nonrheumatic mitral valve disorders
0.836 0.164 0.000
D86.9 Sarcoidosis, unspecified
0.836 0.164 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.835 0.165 0.000
K86.9 Disease of pancreas, unspecified
0.834 0.166 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.834 0.166 0.000
E86 Volume depletion
0.832 0.168 0.000
Chapter XXII Codes for special purposes
0.831 0.169 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.829 0.171 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.829 0.171 0.000
N76 Other inflammation of vagina and vulva
0.824 0.176 0.000
K83 Other diseases of biliary tract
0.824 0.176 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.823 0.177 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.820 0.180 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.820 0.180 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.819 0.180 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.819 0.181 0.000
K72 Hepatic failure, not elsewhere classified
0.819 0.181 0.000
E23 Hypofunction and other disorders of pituitary gland
0.818 0.182 0.000
N17.9 Acute renal failure, unspecified
0.818 0.182 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.817 0.183 0.000
K52 Other non-infective gastro-enteritis and colitis
0.816 0.184 0.000
K51.9 Ulcerative colitis, unspecified
0.816 0.184 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.809 0.191 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.808 0.192 0.000
D11 Benign neoplasm of major salivary glands
0.806 0.194 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.804 0.196 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.804 0.196 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.803 0.197 0.000
I38 Endocarditis, valve unspecified
0.802 0.198 0.000
I70 Atherosclerosis
0.802 0.198 0.000
K86.0 Alcohol-induced chronic pancreatitis
0.801 0.199 0.000
Y40.0 Penicillins
0.800 0.200 0.000
O80-O84 Delivery
0.799 0.201 0.000
E50-E64 Other nutritional deficiencies
0.799 0.201 0.000
V20-V29 Motorcycle rider injured in transport accident
0.798 0.202 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.796 0.204 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.796 0.204 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.795 0.205 0.000
I78 Diseases of capillaries
0.792 0.208 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.791 0.209 0.000
I46.9 Cardiac arrest, unspecified
0.786 0.214 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.785 0.215 0.000
K82 Other diseases of gallbladder
0.784 0.216 0.000
B18 Chronic viral hepatitis
0.782 0.218 0.000
A30-A49 Other bacterial diseases
0.782 0.218 0.000
N20-N23 Urolithiasis
0.781 0.219 0.000
K92 Other diseases of digestive system
0.780 0.220 0.000
D23.3 Skin of other and unspecified parts of face
0.780 0.220 0.000
T81 Complications of procedures, not elsewhere classified
0.779 0.221 0.000
N18.0 End-stage renal disease
0.778 0.222 0.000
Y52 Agents primarily affecting the cardiovascular system
0.777 0.223 0.000
K86.8 Other specified diseases of pancreas
0.777 0.223 0.000
E34 Other endocrine disorders
0.777 0.223 0.000
O85-O92 Complications predominantly related to the puerperium
0.777 0.223 0.000
I73 Other peripheral vascular diseases
0.776 0.224 0.000
O63.0 Prolonged first stage (of labour)
0.775 0.225 0.000
I44.0 Atrioventricular block, first degree
0.774 0.226 0.000
K70.1 Alcoholic hepatitis
0.774 0.226 0.000
F41.2 Mixed anxiety and depressive disorder
0.773 0.227 0.000
N02 Recurrent and persistent haematuria
0.772 0.228 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.772 0.228 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.769 0.230 0.000
E26 Hyperaldosteronism
0.769 0.231 0.000
E28.2 Polycystic ovarian syndrome
0.769 0.231 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.768 0.232 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.768 0.232 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.768 0.232 0.000
B99-B99 Other infectious diseases
0.767 0.233 0.000
T78 Adverse effects, not elsewhere classified
0.767 0.233 0.000
I45.6 Preexcitation syndrome
0.765 0.235 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.765 0.235 0.000
F10.1 Harmful use
0.764 0.236 0.000
B35-B49 Mycoses
0.762 0.238 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.761 0.239 0.000
N18.4 Chronic kidney disease, stage 4
0.760 0.240 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.759 0.241 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.759 0.241 0.000
D51 Vitamin B12 deficiency anaemia
0.759 0.241 0.000
K70.4 Alcoholic hepatic failure
0.758 0.242 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.757 0.243 0.000
K92.0 Haematemesis
0.755 0.245 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.755 0.245 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.754 0.246 0.000
I51 Complications and ill-defined descriptions of heart disease
0.753 0.247 0.000
D23.5 Skin of trunk
0.752 0.248 0.000
N13 Obstructive and reflux uropathy
0.752 0.248 0.000
E29 Testicular dysfunction
0.751 0.249 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.749 0.251 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.749 0.251 0.000
N28.8 Other specified disorders of kidney and ureter
0.747 0.253 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.747 0.253 0.000
S80-S89 Injuries to the knee and lower leg
0.747 0.253 0.000
B65-B83 Helminthiases
0.747 0.253 0.000
I25.3 Aneurysm of heart
0.745 0.255 0.000
K51.8 Other ulcerative colitis
0.744 0.256 0.000
C81 Hodgkin's disease
0.744 0.256 0.000
A80-A89 Viral infections of the central nervous system
0.743 0.256 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.743 0.257 0.000
S60-S69 Injuries to the wrist and hand
0.743 0.257 0.000
I77 Other disorders of arteries and arterioles
0.741 0.259 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.738 0.262 0.000
F10.3 Withdrawal state
0.737 0.263 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.737 0.263 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.736 0.264 0.000
C97 Malignant neoplasms of independent (primary) multiple sites
0.736 0.264 0.000
K50 Crohn's disease [regional enteritis]
0.735 0.265 0.000
F43 Reaction to severe stress, and adjustment disorders
0.735 0.265 0.000
Chapter VIII Diseases of the ear and mastoid process
0.734 0.265 0.000
S90-S99 Injuries to the ankle and foot
0.734 0.266 0.000
I25.2 Old myocardial infarction
0.734 0.266 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.733 0.266 0.000
O21 Excessive vomiting in pregnancy
0.733 0.267 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.733 0.267 0.000
X60-X84 Intentional self-harm
0.732 0.268 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.732 0.268 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.731 0.269 0.000
N18.2 Chronic kidney disease, stage 2
0.731 0.269 0.000
O00-O08 Pregnancy with abortive outcome
0.730 0.270 0.000
D13.0 Oesophagus
0.730 0.270 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.729 0.270 0.000
K70.3 Alcoholic cirrhosis of liver
0.729 0.271 0.000
N76.0 Acute vaginitis
0.728 0.272 0.000
D22 Melanocytic naevi
0.726 0.274 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.725 0.275 0.000
D52 Folate deficiency anaemia
0.724 0.275 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.724 0.276 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.723 0.277 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.723 0.277 0.000
I45.3 Trifascicular block
0.723 0.277 0.000
D23.1 Skin of eyelid, including canthus
0.722 0.278 0.000
N99-N99 Other disorders of the genitourinary system
0.722 0.278 0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head
0.721 0.279 0.000
D55-D59 Haemolytic anaemias
0.720 0.279 0.000
F10.2 Dependence syndrome
0.720 0.280 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.719 0.281 0.000
Y57 Other and unspecified drugs and medicaments
0.718 0.282 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.718 0.282 0.000
D86.0 Sarcoidosis of lung
0.717 0.283 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I30 Acute pericarditis
0.717 0.283 0.000
K86.1 Other chronic pancreatitis
0.716 0.283 0.000
K52.1 Toxic gastro-enteritis and colitis
0.716 0.284 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.716 0.284 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.716 0.284 0.000
B50-B64 Protozoal diseases
0.716 0.284 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.716 0.284 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.716 0.284 0.000
A75-A79 Rickettsioses
0.716 0.284 0.000
A70-A74 Other diseases caused by chlamydiae
0.716 0.284 0.000
A65-A69 Other spirochaetal diseases
0.716 0.284 0.000
A20-A28 Certain zoonotic bacterial diseases
0.716 0.284 0.000
A15-A19 Tuberculosis
0.716 0.284 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.716 0.284 0.000
N18.8 Other chronic renal failure
0.716 0.284 0.000
N18.1 Chronic kidney disease, stage 1
0.716 0.284 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.716 0.284 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.715 0.284 0.000
D23.7 Skin of lower limb, including hip
0.715 0.285 0.000
D11.0 Parotid gland
0.714 0.286 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.713 0.287 0.000
K72.9 Hepatic failure, unspecified
0.713 0.287 0.000
O43 Placental disorders
0.713 0.287 0.000
I34.1 Mitral (valve) prolapse
0.713 0.287 0.000
B18.2 Chronic viral hepatitis C
0.712 0.287 0.000
Q80-Q89 Other congenital malformations
0.711 0.288 0.000
D26 Other benign neoplasms of uterus
0.711 0.289 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.710 0.290 0.000
I33 Acute and subacute endocarditis
0.710 0.290 0.000
I44.3 Other and unspecified atrioventricular block
0.709 0.291 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.709 0.291 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.709 0.291 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.709 0.291 0.000
N21 Calculus of lower urinary tract
0.708 0.292 0.000
K70.0 Alcoholic fatty liver
0.708 0.292 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.708 0.292 0.000
D50.8 Other iron deficiency anaemias
0.707 0.293 0.000
D32 Benign neoplasm of meninges
0.707 0.293 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.707 0.293 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.706 0.293 0.000
K82.1 Hydrops of gallbladder
0.706 0.294 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.706 0.294 0.000
K83.1 Obstruction of bile duct
0.706 0.294 0.000
K91.4 Colostomy and enterostomy malfunction
0.706 0.294 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.704 0.296 0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
0.704 0.296 0.000
K51.4 Pseudopolyposis of colon
0.703 0.297 0.000
V40-V49 Car occupant injured in transport accident
0.702 0.297 0.000
N76.8 Other specified inflammation of vagina and vulva
0.702 0.298 0.000
D29 Benign neoplasm of male genital organs
0.701 0.299 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.701 0.299 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.700 0.299 0.000
K74 Fibrosis and cirrhosis of liver
0.700 0.300 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.700 0.300 0.000
E32 Diseases of thymus
0.700 0.300 0.000
E31 Polyglandular dysfunction
0.700 0.300 0.000
E30 Disorders of puberty, not elsewhere classified
0.700 0.300 0.000
E25 Adrenogenital disorders
0.700 0.300 0.000
E24 Cushing's syndrome
0.700 0.300 0.000
E20 Hypoparathyroidism
0.700 0.300 0.000
F40 Phobic anxiety disorders
0.700 0.300 0.000
E83 Disorders of mineral metabolism
0.700 0.300 0.000
K51.5 Mucosal proctocolitis
0.697 0.303 0.000
S70-S79 Injuries to the hip and thigh
0.697 0.303 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.695 0.305 0.000
O30 Multiple gestation
0.695 0.305 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.694 0.306 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.694 0.306 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.694 0.306 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.694 0.306 0.000
K86.2 Cyst of pancreas
0.693 0.307 0.000
E23.2 Diabetes insipidus
0.693 0.307 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.693 0.307 0.000
K65-K67 Diseases of peritoneum
0.692 0.308 0.000
E87.5 Hyperkalaemia
0.691 0.309 0.000
I72.8 Aneurysm of other specified arteries
0.691 0.309 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.691 0.309 0.000
I05-I09 Chronic rheumatic heart diseases
0.690 0.310 0.000
O44 Placenta praevia
0.690 0.310 0.000
I35.8 Other aortic valve disorders
0.690 0.310 0.000
K77 Liver disorders in diseases classified elsewhere
0.690 0.310 0.000
K73 Chronic hepatitis, not elsewhere classified
0.690 0.310 0.000
K71 Toxic liver disease
0.690 0.310 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.689 0.311 0.000
E40-E46 Malnutrition
0.689 0.311 0.000
N03 Chronic nephritic syndrome
0.688 0.312 0.000
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere
0.688 0.312 0.000
I72.4 Aneurysm of artery of lower extremity
0.688 0.312 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.687 0.313 0.000
O74 Complications of anaesthesia during labour and delivery
0.687 0.313 0.000
O71 Other obstetric trauma
0.687 0.313 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.687 0.313 0.000
O61 Failed induction of labour
0.687 0.313 0.000
O60 Preterm delivery
0.687 0.313 0.000
I45.1 Other and unspecified right bundle-branch block
0.687 0.313 0.000
D13.2 Duodenum
0.686 0.314 0.000
N76.5 Ulceration of vagina
0.686 0.314 0.000
T86 Failure and rejection of transplanted organs and tissues
0.686 0.314 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.686 0.314 0.000
F70-F79 Mental retardation
0.686 0.314 0.000
F60-F69 Disorders of adult personality and behaviour
0.686 0.314 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.686 0.314 0.000
D68 Other coagulation defects
0.686 0.314 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.685 0.315 0.000
N72 Inflammatory disease of cervix uteri
0.684 0.316 0.000
I73.9 Peripheral vascular disease, unspecified
0.684 0.316 0.000
T33-T35 Frostbite
0.684 0.316 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.684 0.316 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.684 0.316 0.000
T00-T07 Injuries involving multiple body regions
0.684 0.316 0.000
S10-S19 Injuries to the neck
0.684 0.316 0.000
K75 Other inflammatory liver diseases
0.683 0.317 0.000
I25.6 Silent myocardial ischaemia
0.682 0.318 0.000
I25.4 Coronary artery aneurysm
0.682 0.318 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.682 0.318 0.000
D53 Other nutritional anaemias
0.682 0.318 0.000
K51.2 Ulcerative (chronic) proctitis
0.680 0.320 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.679 0.321 0.000
T90 Sequelae of injuries of head
0.678 0.321 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.678 0.322 0.000
I42 Cardiomyopathy
0.678 0.322 0.000
K70.2 Alcoholic fibrosis and sclerosis of liver
0.677 0.322 0.000
O62 Abnormalities of forces of labour
0.677 0.323 0.000
F41.1 Generalised anxiety disorder
0.677 0.323 0.000
T93 Sequelae of injuries of lower limb
0.677 0.323 0.000
F80-F89 Disorders of psychological development
0.676 0.324 0.000
I44.2 Atrioventricular block, complete
0.676 0.324 0.000
I44.1 Atrioventricular block, second degree
0.675 0.325 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.675 0.325 0.000
T92 Sequelae of injuries of upper limb
0.675 0.325 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.675 0.325 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.674 0.326 0.000
I51.8 Other ill-defined heart diseases
0.674 0.326 0.000
C85.1 B-cell lymphoma, unspecified
0.674 0.326 0.000
I24 Other acute ischaemic heart diseases
0.674 0.326 0.000
Q50-Q56 Congenital malformations of genital organs
0.674 0.326 0.000
N02.9 Unspecified
0.674 0.326 0.000
K35-K38 Diseases of appendix
0.673 0.327 0.000
Y44 Agents primarily affecting blood constituents
0.673 0.327 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.672 0.328 0.000
T87 Complications peculiar to reattachment and amputation
0.672 0.328 0.000
M20-M25 Other joint disorders
0.672 0.328 0.000
D84 Other immunodeficiencies
0.671 0.329 0.000
D83 Common variable immunodeficiency
0.671 0.329 0.000
D82 Immunodeficiency associated with other major defects
0.671 0.329 0.000
D81 Combined immunodeficiencies
0.671 0.329 0.000
D80 Immunodeficiency with predominantly antibody defects
0.671 0.329 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.671 0.329 0.000
E22 Hyperfunction of pituitary gland
0.671 0.329 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.671 0.329 0.000
T78.2 Anaphylactic shock, unspecified
0.670 0.330 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.670 0.330 0.000
D31 Benign neoplasm of eye and adnexa
0.670 0.330 0.000
D30 Benign neoplasm of urinary organs
0.670 0.330 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.670 0.330 0.000
D19 Benign neoplasm of mesothelial tissue
0.670 0.330 0.000
D16 Benign neoplasm of bone and articular cartilage
0.670 0.330 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.670 0.330 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.669 0.331 0.000
I74 Arterial embolism and thrombosis
0.668 0.332 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.668 0.332 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.668 0.332 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.668 0.332 0.000
E27.9 Disorder of adrenal gland, unspecified
0.667 0.332 0.000
E27.8 Other specified disorders of adrenal gland
0.667 0.332 0.000
E27.5 Adrenomedullary hyperfunction
0.667 0.332 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.667 0.332 0.000
E27.2 Addisonian crisis
0.667 0.332 0.000
E27.0 Other adrenocortical overactivity
0.667 0.332 0.000
I44.6 Other and unspecified fascicular block
0.667 0.332 0.000
D22.3 Melanocytic naevi of other and unspecified parts of face
0.667 0.332 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.667 0.333 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.667 0.333 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.667 0.333 0.000
V10-V19 Pedal cyclist injured in transport accident
0.667 0.333 0.000
O66 Other obstructed labour
0.666 0.334 0.000
O73 Retained placenta and membranes, without haemorrhage
0.666 0.334 0.000
D18 Haemangioma and lymphangioma, any site
0.666 0.334 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.665 0.335 0.000
E87.7 Fluid overload
0.665 0.335 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.665 0.335 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.664 0.336 0.000
T88.5 Other complications of anaesthesia
0.664 0.336 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.663 0.337 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.663 0.337 0.000
K81 Cholecystitis
0.663 0.337 0.000
C71 Malignant neoplasm of brain
0.661 0.338 0.000
S80 Superficial injury of lower leg
0.662 0.338 0.000
B17 Other acute viral hepatitis
0.661 0.338 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.661 0.339 0.000
T79-T79 Certain early complications of trauma
0.660 0.340 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.660 0.340 0.000
Y35-Y36 Legal intervention and operations of war
0.660 0.340 0.000
Y10-Y34 Event of undetermined intent
0.660 0.340 0.000
Y00-Y09 Assault
0.660 0.340 0.000
X85-X99 Assault
0.660 0.340 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.660 0.340 0.000
X50-X57 Overexertion, travel and privation
0.660 0.340 0.000
X30-X39 Exposure to forces of nature
0.660 0.340 0.000
X20-X29 Contact with venomous animals and plants
0.660 0.340 0.000
X10-X19 Contact with heat and hot substances
0.660 0.340 0.000
X00-X09 Exposure to smoke, fire and flames
0.660 0.340 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.660 0.340 0.000
W75-W84 Other accidental threats to breathing
0.660 0.340 0.000
W65-W74 Accidental drowning and submersion
0.660 0.340 0.000
W50-W64 Exposure to animate mechanical forces
0.660 0.340 0.000
V98-V99 Other and unspecified transport accidents
0.660 0.340 0.000
V95-V97 Air and space transport accidents
0.660 0.340 0.000
V90-V94 Water transport accidents
0.660 0.340 0.000
V80-V89 Other land transport accidents
0.660 0.340 0.000
V70-V79 Bus occupant injured in transport accident
0.660 0.340 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.660 0.340 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.660 0.340 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.660 0.340 0.000
V01-V09 Pedestrian injured in transport accident
0.660 0.340 0.000
I78.1 Naevus, nonneoplastic
0.659 0.341 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.659 0.341 0.000
I35.9 Aortic valve disorder, unspecified
0.659 0.341 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.658 0.342 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.658 0.342 0.000
N21.0 Calculus in bladder
0.656 0.344 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.656 0.344 0.000
O45 Premature separation of placenta [abruptio placentae]
0.654 0.345 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.654 0.345 0.000
O33 Maternal care for known or suspected disproportion
0.654 0.345 0.000
O31 Complications specific to multiple gestation
0.654 0.345 0.000
O40 Polyhydramnios
0.654 0.345 0.000
K85 Acute pancreatitis
0.654 0.346 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.653 0.347 0.000
C95 Leukaemia of unspecified cell type
0.653 0.347 0.000
C94 Other leukaemias of specified cell type
0.653 0.347 0.000
C93 Monocytic leukaemia
0.653 0.347 0.000
C88 Malignant immunoproliferative diseases
0.653 0.347 0.000
C86 Other specified types of T/NK-cell lymphoma
0.653 0.347 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.653 0.347 0.000
O63.2 Delayed delivery of second twin, triplet, etc.
0.652 0.348 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.652 0.348 0.000
N15 Other renal tubulo-interstitial diseases
0.652 0.348 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.652 0.348 0.000
N11 Chronic tubulo-interstitial nephritis
0.652 0.348 0.000
N10 Acute tubulo-interstitial nephritis
0.652 0.348 0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours
0.652 0.348 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.652 0.348 0.000
N06 Isolated proteinuria with specified morphological lesion
0.652 0.348 0.000
N05 Unspecified nephritic syndrome
0.652 0.348 0.000
N01 Rapidly progressive nephritic syndrome
0.652 0.348 0.000
N00 Acute nephritic syndrome
0.652 0.348 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.652 0.348 0.000
N18.5 Chronic kidney disease, stage 5
0.651 0.348 0.000
I45.9 Conduction disorder, unspecified
0.651 0.349 0.000
I70.0 Atherosclerosis of aorta
0.651 0.349 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.651 0.349 0.000
F48 Other neurotic disorders
0.650 0.350 0.000
F44 Dissociative [conversion] disorders
0.650 0.350 0.000
F42 Obsessive-compulsive disorder
0.650 0.350 0.000
D50.1 Sideropenic dysphagia
0.650 0.350 0.000
N04 Nephrotic syndrome
0.650 0.350 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.649 0.350 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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