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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17843619
log Bayes Factor = 439.369
Chromosome 6   position 32,620,775  (GRCh37) Explore rs17843619 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
D64.9 Anaemia, unspecified
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
J33.9 Nasal polyp, unspecified
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K51.9 Ulcerative colitis, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
K51 Ulcerative colitis
1.000 0.000 0.000
N48 Other disorders of penis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
J33 Nasal polyp
0.000 0.000 1.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.000 1.000
E14.9 Without complications
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
E10.4 With neurological complications
0.000 0.000 1.000
E11.3 With ophthalmic complications
0.000 0.000 1.000
D50-D53 Nutritional anaemias
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
E14.3 With ophthalmic complications
0.000 0.000 1.000
N40-N51 Diseases of male genital organs
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
C21 Malignant neoplasm of anus and anal canal
0.000 0.000 1.000
K70-K77 Diseases of liver
0.000 0.000 1.000
Chapter XI Diseases of the digestive system
0.000 0.000 1.000
Chapter II Neoplasms
0.000 0.000 1.000
D00-D09 In situ neoplasms
0.000 0.000 1.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.000 1.000
N47 Redundant prepuce, phimosis and paraphimosis
0.000 0.000 1.000
K90 Intestinal malabsorption
0.000 0.000 1.000
J33.0 Polyp of nasal cavity
0.000 0.001 0.999
K75 Other inflammatory liver diseases
0.000 0.001 0.999
C15-C26 Malignant neoplasms of digestive organs
0.000 0.001 0.999
M05-M14 Inflammatory polyarthropathies
0.000 0.001 0.999
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.001 0.999
K75.4 Autoimmune hepatitis
0.000 0.001 0.999
D64 Other anaemias
0.000 0.001 0.999
D50 Iron deficiency anaemia
0.000 0.001 0.999
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.001 0.999
M05 Seropositive rheumatoid arthritis
0.000 0.001 0.999
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.001 0.999
C21.0 Anus, unspecified
0.000 0.001 0.999
D60-D64 Aplastic and other anaemias
0.000 0.001 0.999
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.001 0.999
E83.1 Disorders of iron metabolism
0.999 0.001 0.000
K90-K93 Other diseases of the digestive system
0.000 0.001 0.999
Chapter XIV Diseases of the genitourinary system
0.000 0.001 0.999
D50.9 Iron deficiency anaemia, unspecified
0.000 0.001 0.999
D07 Carcinoma in situ of other and unspecified genital organs
0.000 0.001 0.999
N00-N08 Glomerular diseases
0.000 0.002 0.998
H36 Retinal disorders in diseases classified elsewhere
0.000 0.002 0.998
D07.1 Vulva
0.000 0.002 0.998
L90 Atrophic disorders of skin
0.000 0.002 0.998
N48.6 Balanitis xerotica obliterans
0.000 0.002 0.998
L90.0 Lichen sclerosus et atrophicus
0.000 0.002 0.998
H30-H36 Disorders of choroid and retina
0.000 0.003 0.997
D06 Carcinoma in situ of cervix uteri
0.000 0.003 0.997
E20-E35 Disorders of other endocrine glands
0.000 0.004 0.996
K51.4 Pseudopolyposis of colon
0.996 0.004 0.000
Chapter VII Diseases of the eye and adnexa
0.000 0.004 0.996
E10.5 With peripheral circulatory complications
0.000 0.004 0.996
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.004 0.996
L92 Granulomatous disorders of skin and subcutaneous tissue
0.000 0.005 0.995
N48.1 Balanoposthitis
0.000 0.005 0.995
J45 Asthma
0.000 0.005 0.995
D06.9 Cervix, unspecified
0.000 0.006 0.994
C21.1 Anal canal
0.000 0.006 0.994
H43-H45 Disorders of vitreous body and globe
0.000 0.008 0.992
E27 Other disorders of adrenal gland
0.000 0.008 0.992
E11.1 With ketoacidosis
0.000 0.009 0.991
N08 Glomerular disorders in diseases classified elsewhere
0.000 0.009 0.991
H43 Disorders of vitreous body
0.000 0.009 0.991
D51 Vitamin B12 deficiency anaemia
0.000 0.010 0.990
E27.1 Primary adrenocortical insufficiency
0.000 0.011 0.989
J40-J47 Chronic lower respiratory diseases
0.000 0.011 0.989
N05 Unspecified nephritic syndrome
0.000 0.011 0.989
N08.3 Glomerular disorders in diabetes mellitus
0.000 0.012 0.988
Chapter X Diseases of the respiratory system
0.000 0.012 0.988
K51.3 Ulcerative (chronic) rectosigmoiditis
0.986 0.014 0.000
H43.1 Vitreous haemorrhage
0.000 0.015 0.985
L92.0 Granuloma annulare
0.000 0.016 0.984
J33.8 Other polyp of sinus
0.000 0.016 0.984
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.016 0.984
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.018 0.982
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.000 0.018 0.982
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.021 0.979
E10.2 With renal complications
0.000 0.024 0.976
K51.2 Ulcerative (chronic) proctitis
0.974 0.026 0.000
N48.0 Leukoplakia of penis
0.000 0.027 0.973
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.028 0.972
C20 Malignant neoplasm of rectum
0.000 0.032 0.968
E10.0 With coma
0.000 0.035 0.965
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.037 0.963
E10.8 With unspecified complications
0.000 0.038 0.962
E11.5 With peripheral circulatory complications
0.000 0.040 0.960
J46 Status asthmaticus
0.000 0.040 0.960
E07 Other disorders of thyroid
0.000 0.040 0.960
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.000 0.040 0.960
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.044 0.956
Chapter IX Diseases of the circulatory system
0.000 0.045 0.955
I20-I25 Ischaemic heart diseases
0.000 0.046 0.954
C09 Malignant neoplasm of tonsil
0.000 0.047 0.953
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.048 0.952
E10.6 With other specified complications
0.000 0.048 0.952
H34 Retinal vascular occlusions
0.000 0.048 0.952
L80 Vitiligo
0.000 0.053 0.947
K51.8 Other ulcerative colitis
0.947 0.053 0.000
N04 Nephrotic syndrome
0.000 0.057 0.943
K90.9 Intestinal malabsorption, unspecified
0.000 0.058 0.942
E07.9 Disorder of thyroid, unspecified
0.000 0.059 0.941
K51.5 Mucosal proctocolitis
0.939 0.061 0.000
K72 Hepatic failure, not elsewhere classified
0.000 0.061 0.939
M06.3 Rheumatoid nodule
0.000 0.065 0.935
N49.2 Inflammatory disorders of scrotum
0.000 0.067 0.933
C09.9 Tonsil, unspecified
0.000 0.067 0.933
L40-L45 Papulosquamous disorders
0.000 0.069 0.931
K73 Chronic hepatitis, not elsewhere classified
0.000 0.070 0.930
Chapter VI Diseases of the nervous system
0.000 0.073 0.927
I24 Other acute ischaemic heart diseases
0.000 0.073 0.927
I20 Angina pectoris
0.000 0.074 0.926
H34.8 Other retinal vascular occlusions
0.000 0.075 0.925
J30-J39 Other diseases of upper respiratory tract
0.000 0.076 0.924
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.000 0.078 0.922
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.079 0.921
E11.2 With renal complications
0.000 0.080 0.920
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.000 0.080 0.920
I25 Chronic ischaemic heart disease
0.000 0.080 0.920
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.081 0.919
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.083 0.917
G35-G37 Demyelinating diseases of the central nervous system
0.849 0.086 0.066
J95-J99 Other diseases of the respiratory system
0.000 0.086 0.913
E24 Cushing's syndrome
0.000 0.087 0.913
H43.8 Other disorders of vitreous body
0.000 0.087 0.913
I20.9 Angina pectoris, unspecified
0.000 0.088 0.912
L40 Psoriasis
0.000 0.090 0.910
G63 Polyneuropathy in diseases classified elsewhere
0.000 0.091 0.909
K75.8 Other specified inflammatory liver diseases
0.000 0.092 0.908
C91.1 Chronic lymphocytic leukaemia
0.000 0.094 0.906
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.095 0.905
E13 Other specified diabetes mellitus
0.000 0.095 0.905
L40.9 Psoriasis, unspecified
0.000 0.097 0.903
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.098 0.902
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.000 0.098 0.902
N05.2 Diffuse membranous glomerulonephritis
0.000 0.098 0.902
G63.2 Diabetic polyneuropathy
0.000 0.099 0.901
E21.0 Primary hyperparathyroidism
0.000 0.100 0.900
E16.1 Other hypoglycaemia
0.000 0.101 0.899
M06.4 Inflammatory polyarthropathy
0.000 0.103 0.897
I25.5 Ischaemic cardiomyopathy
0.000 0.104 0.896
C91 Lymphoid leukaemia
0.000 0.105 0.895
I74 Arterial embolism and thrombosis
0.000 0.106 0.894
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.107 0.893
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.110 0.890
H43.3 Other vitreous opacities
0.000 0.111 0.889
E06 Thyroiditis
0.000 0.114 0.886
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.115 0.885
N05.1 Focal and segmental glomerular lesions
0.000 0.120 0.880
N04.9 Unspecified
0.000 0.121 0.879
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.121 0.879
D50.8 Other iron deficiency anaemias
0.000 0.122 0.878
L10-L14 Bullous disorders
0.000 0.125 0.875
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.126 0.874
K55-K64 Other diseases of intestines
0.000 0.126 0.874
E11.6 With other specified complications
0.000 0.127 0.873
N48.4 Impotence of organic origin
0.000 0.127 0.873
K60 Fissure and fistula of anal and rectal regions
0.000 0.132 0.868
E14.8 With unspecified complications
0.000 0.132 0.868
K60.2 Anal fissure, unspecified
0.000 0.139 0.861
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.141 0.859
K72.0 Acute and subacute hepatic failure
0.000 0.141 0.859
I77 Other disorders of arteries and arterioles
0.000 0.141 0.859
N48.2 Other inflammatory disorders of penis
0.000 0.143 0.857
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.000 0.143 0.857
D01 Carcinoma in situ of other and unspecified digestive organs
0.000 0.144 0.856
E14.1 With ketoacidosis
0.000 0.145 0.855
E03.8 Other specified hypothyroidism
0.000 0.147 0.853
J86 Pyothorax
0.000 0.149 0.851
D07.4 Penis
0.000 0.150 0.850
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.150 0.850
E50-E64 Other nutritional deficiencies
0.000 0.153 0.847
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.000 0.158 0.842
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.159 0.841
G50-G59 Nerve, nerve root and plexus disorders
0.000 0.159 0.841
E21.3 Hyperparathyroidism, unspecified
0.000 0.160 0.840
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.161 0.839
J45.0 Predominantly allergic asthma
0.000 0.161 0.839
I20.0 Unstable angina
0.000 0.162 0.838
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.162 0.838
N05.8 Other
0.000 0.164 0.835
E06.3 Autoimmune thyroiditis
0.000 0.166 0.834
K55 Vascular disorders of intestine
0.000 0.167 0.833
G00-G09 Inflammatory diseases of the central nervous system
0.000 0.169 0.831
I74.8 Embolism and thrombosis of other arteries
0.000 0.169 0.831
I74.5 Embolism and thrombosis of iliac artery
0.000 0.169 0.831
E13.9 Without complications
0.000 0.171 0.829
E14.5 With peripheral circulatory complications
0.000 0.171 0.829
M45-M49 Spondylopathies
0.000 0.172 0.828
K51.0 Ulcerative (chronic) enterocolitis
0.828 0.172 0.000
G56.0 Carpal tunnel syndrome
0.000 0.175 0.825
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.176 0.824
E14.6 With other specified complications
0.000 0.177 0.823
C22.9 Liver, unspecified
0.000 0.177 0.823
K55.2 Angiodysplasia of colon
0.000 0.177 0.823
G56 Mononeuropathies of upper limb
0.000 0.178 0.822
C23 Malignant neoplasm of gallbladder
0.000 0.179 0.821
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.181 0.819
K74 Fibrosis and cirrhosis of liver
0.000 0.181 0.819
N05.9 Unspecified
0.000 0.182 0.818
E20 Hypoparathyroidism
0.000 0.183 0.817
G37 Other demyelinating diseases of central nervous system
0.798 0.184 0.018
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.184 0.816
C04 Malignant neoplasm of floor of mouth
0.000 0.185 0.814
E27.2 Addisonian crisis
0.000 0.187 0.813
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.187 0.813
M14 Arthropathies in other diseases classified elsewhere
0.000 0.188 0.812
E53 Deficiency of other B group vitamins
0.000 0.188 0.812
I10-I15 Hypertensive diseases
0.000 0.190 0.810
J86.0 Pyothorax with fistula
0.000 0.191 0.809
J98 Other respiratory disorders
0.000 0.193 0.807
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.194 0.806
C21.8 Overlapping lesion of rectum, anus and anal canal
0.000 0.198 0.802
E14.4 With neurological complications
0.000 0.202 0.797
C07 Malignant neoplasm of parotid gland
0.000 0.203 0.797
G61 Inflammatory polyneuropathy
0.000 0.204 0.796
E14.2 Withrenal complications
0.000 0.205 0.795
K60.0 Acute anal fissure
0.000 0.205 0.795
K72.9 Hepatic failure, unspecified
0.000 0.206 0.794
G70-G73 Diseases of myoneural junction and muscle
0.000 0.208 0.792
E11.0 With coma
0.000 0.209 0.791
E53.8 Deficiency of other specified B group vitamins
0.000 0.209 0.791
J98.0 Diseases of bronchus, not elsewhere classified
0.000 0.210 0.790
D04 Carcinoma in situ of skin
0.000 0.211 0.789
I25.2 Old myocardial infarction
0.000 0.211 0.789
C22.1 Intrahepatic bile duct carcinoma
0.000 0.213 0.787
C10 Malignant neoplasm of oropharynx
0.000 0.214 0.786
N48.9 Disorder of penis, unspecified
0.000 0.214 0.786
C12 Malignant neoplasm of pyriform sinus
0.000 0.219 0.781
M12 Other specific arthropathies
0.000 0.219 0.781
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.221 0.779
I77.6 Arteritis, unspecified
0.000 0.221 0.779
E24.0 Pituitary-dependent Cushing's disease
0.000 0.221 0.779
G00 Bacterial meningitis, not elsewhere classified
0.000 0.222 0.778
D06.0 Endocervix
0.000 0.223 0.777
K60.1 Chronic anal fissure
0.000 0.225 0.775
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.225 0.775
G59 Mononeuropathy in diseases classified elsewhere
0.000 0.227 0.773
C02 Malignant neoplasm of other and unspecified parts of tongue
0.000 0.227 0.773
E24.9 Cushing's syndrome, unspecified
0.000 0.232 0.768
M48 Other spondylopathies
0.000 0.232 0.768
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.232 0.768
L13 Other bullous disorders
0.000 0.233 0.767
G60 Hereditary and idiopathic neuropathy
0.000 0.236 0.764
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.239 0.761
K57 Diverticular disease of intestine
0.000 0.239 0.761
C11 Malignant neoplasm of nasopharynx
0.000 0.239 0.761
L94 Other localised connective tissue disorders
0.000 0.239 0.761
G37.9 Demyelinating disease of central nervous system, unspecified
0.757 0.241 0.003
E05.8 Other thyrotoxicosis
0.000 0.241 0.759
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.242 0.758
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.243 0.757
N48.5 Ulcer of penis
0.000 0.244 0.755
N04.1 Focal and segmental glomerular lesions
0.000 0.245 0.754
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.246 0.754
K57.3 Diverticular disease of large intestine without perforation or abscess
0.000 0.246 0.754
I10 Essential (primary) hypertension
0.000 0.246 0.754
L95 Vasculitis limited to skin, not elsewhere classified
0.000 0.248 0.752
M06.8 Other specified rheumatoid arthritis
0.000 0.250 0.750
N51 Disorders of male genital organs in diseases classified elsewhere
0.000 0.250 0.750
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.251 0.749
J45.1 Nonallergic asthma
0.000 0.254 0.746
C13 Malignant neoplasm of hypopharynx
0.000 0.254 0.746
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.259 0.741
H31 Other disorders of choroid
0.000 0.259 0.741
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.266 0.734
E83 Disorders of mineral metabolism
0.731 0.268 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.270 0.730
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.270 0.730
M48.0 Spinal stenosis
0.000 0.271 0.729
M06.34 Rheumatoid nodule (Hand)
0.000 0.273 0.727
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.274 0.726
C60-C63 Malignant neoplasms of male genital organs
0.000 0.274 0.726
L12 Pemphigoid
0.000 0.275 0.725
G59.0 Diabetic mononeuropathy
0.000 0.276 0.724
M14.6 Neuropathic arthropathy
0.000 0.276 0.724
M05.2 Rheumatoid vasculitis
0.000 0.276 0.724
K73.9 Chronic hepatitis, unspecified
0.000 0.277 0.723
G00.1 Pneumococcal meningitis
0.000 0.278 0.722
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.279 0.721
E21.2 Other hyperparathyroidism
0.000 0.280 0.720
J44 Other chronic obstructive pulmonary disease
0.000 0.280 0.720
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.280 0.720
H30 Chorioretinal inflammation
0.000 0.282 0.718
N05.7 Diffuse crescentic glomerulonephritis
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
C21.2 Cloacogenic zone
0.000 0.283 0.717
K77 Liver disorders in diseases classified elsewhere
0.000 0.283 0.717
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.000 0.283 0.717
L87 Transepidermal elimination disorders
0.000 0.283 0.717
L86 Keratoderma in diseases classified elsewhere
0.000 0.283 0.717
K90.3 Pancreatic steatorrhoea
0.000 0.283 0.717
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.283 0.717
K90.1 Tropical sprue
0.000 0.283 0.717
K75.2 Nonspecific reactive hepatitis
0.000 0.283 0.716
K75.1 Phlebitis of portal vein
0.000 0.283 0.716
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.716
M08 Juvenile arthritis
0.000 0.283 0.716
D64.4 Congenital dyserythropoietic anaemia
0.000 0.284 0.716
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.284 0.716
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.284 0.716
D64.0 Hereditary sideroblastic anaemia
0.000 0.284 0.716
D50.1 Sideropenic dysphagia
0.000 0.284 0.716
M05.8 Other seropositive rheumatoid arthritis
0.000 0.284 0.716
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.284 0.716
M05.1 Rheumatoid lung disease
0.000 0.284 0.716
M05.0 Felty's syndrome
0.000 0.284 0.716
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.284 0.716
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.284 0.716
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.284 0.716
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.284 0.716
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.284 0.716
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.284 0.716
D07.6 Other and unspecified male genital organs
0.000 0.284 0.716
D07.3 Other and unspecified female genital organs
0.000 0.284 0.716
D07.0 Endometrium
0.000 0.284 0.716
N07 Hereditary nephropathy, not elsewhere classified
0.000 0.284 0.716
N06 Isolated proteinuria with specified morphological lesion
0.000 0.284 0.716
N01 Rapidly progressive nephritic syndrome
0.000 0.284 0.716
N00 Acute nephritic syndrome
0.000 0.284 0.716
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.284 0.716
L90.9 Atrophic disorder of skin, unspecified
0.000 0.284 0.716
L90.6 Striae atrophicae
0.000 0.284 0.716
L90.4 Acrodermatitis chronica atrophicans
0.000 0.284 0.716
L90.3 Atrophoderma of Pasini and Pierini
0.000 0.284 0.716
L90.2 Anetoderma of Jadassohn-Pellizzari
0.000 0.284 0.716
L90.1 Anetoderma of Schweninger-Buzzi
0.000 0.284 0.716
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.285 0.715
D06.7 Other parts of cervix
0.000 0.285 0.714
D06.1 Exocervix
0.000 0.285 0.714
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.286 0.714
E32 Diseases of thymus
0.000 0.286 0.714
E31 Polyglandular dysfunction
0.000 0.286 0.714
E30 Disorders of puberty, not elsewhere classified
0.000 0.286 0.714
C01 Malignant neoplasm of base of tongue
0.000 0.286 0.714
N44 Torsion of testis
0.000 0.286 0.714
C91.0 Acute lymphoblastic leukaemia
0.000 0.286 0.714
L92.2 Granuloma faciale [eosinophilic granuloma of skin]
0.000 0.286 0.713
L92.1 Necrobiosis lipoidica, not elsewhere classified
0.000 0.286 0.713
L40.0 Psoriasis vulgaris
0.000 0.287 0.713
M45 Ankylosing spondylitis
0.000 0.287 0.713
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.287 0.713
C91.9 Lymphoid leukaemia, unspecified
0.000 0.287 0.713
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.288 0.712
D01.3 Anus and anal canal
0.000 0.288 0.712
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.289 0.711
E27.5 Adrenomedullary hyperfunction
0.000 0.289 0.711
E27.0 Other adrenocortical overactivity
0.000 0.289 0.711
K86 Other diseases of pancreas
0.000 0.289 0.711
L40.1 Generalised pustular psoriasis
0.000 0.289 0.711
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.000 0.289 0.710
N08.8 Glomerular disorders in other diseases classified elsewhere
0.000 0.289 0.710
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.000 0.289 0.710
N08.1 Glomerular disorders in neoplastic diseases
0.000 0.289 0.710
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.000 0.289 0.710
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.290 0.710
D51.2 Transcobalamin II deficiency
0.000 0.290 0.710
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.290 0.710
N05.6 Dense deposit disease
0.000 0.291 0.709
N05.4 Diffuse endocapillary proliferative glomerulonephritis
0.000 0.291 0.709
N05.0 Minor glomerular abnormality
0.000 0.291 0.709
E21.4 Other specified disorders of parathyroid gland
0.000 0.292 0.707
I25.1 Atherosclerotic heart disease
0.000 0.292 0.708
E24.2 Drug-induced Cushing's syndrome
0.000 0.293 0.706
N04.2 Diffuse membranous glomerulonephritis
0.000 0.294 0.706
G72 Other myopathies
0.000 0.294 0.706
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.295 0.705
G61.0 Guillain-Barre syndrome
0.000 0.297 0.703
I77.8 Other specified disorders of arteries and arterioles
0.000 0.298 0.702
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens
0.000 0.298 0.702
H34.2 Other retinal artery occlusions
0.000 0.299 0.701
E11.8 With unspecified complications
0.000 0.299 0.701
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.000 0.302 0.698
D53 Other nutritional anaemias
0.000 0.302 0.698
K71 Toxic liver disease
0.000 0.304 0.696
H43.0 Vitreous prolapse
0.000 0.304 0.695
C04.9 Floor of mouth, unspecified
0.000 0.306 0.694
D04.9 Skin, unspecified
0.000 0.306 0.694
D01.0 Colon
0.000 0.306 0.694
G51 Facial nerve disorders
0.000 0.307 0.693
M10 Gout
0.000 0.310 0.690
L13.0 Dermatitis herpetiformis
0.000 0.310 0.690
E07.1 Dyshormogenetic goitre
0.000 0.312 0.688
E07.0 Hypersecretion of calcitonin
0.000 0.312 0.688
N49.9 Inflammatory disorder of unspecified male genital organ
0.000 0.312 0.688
N49.0 Inflammatory disorders of seminal vesicle
0.000 0.312 0.688
E20.9 Hypoparathyroidism, unspecified
0.000 0.312 0.688
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.000 0.313 0.687
D07.2 Vagina
0.000 0.315 0.685
H43.2 Crystalline deposits in vitreous body
0.000 0.316 0.684
M06.1 Adult-onset Still's disease
0.000 0.316 0.684
H34.9 Retinal vascular occlusion, unspecified
0.000 0.316 0.684
C09.8 Overlapping lesion of tonsil
0.000 0.316 0.683
C09.1 Tonsillar pillar (anterior) (posterior)
0.000 0.316 0.683
K86.3 Pseudocyst of pancreas
0.000 0.317 0.683
H34.0 Transient retinal artery occlusion
0.000 0.317 0.682
M49 Spondylopathies in diseases classified elsewhere
0.000 0.318 0.682
C09.0 Tonsillar fossa
0.000 0.318 0.682
K55.8 Other vascular disorders of intestine
0.000 0.318 0.682
C08 Malignant neoplasm of other and unspecified major salivary glands
0.000 0.319 0.681
C95 Leukaemia of unspecified cell type
0.000 0.320 0.680
M48.09 Spinal stenosis (Site unspecified)
0.000 0.320 0.680
E83.3 Disorders of phosphorus metabolism
0.679 0.321 0.000
E03.1 Congenital hypothyroidism without goitre
0.000 0.321 0.679
M11 Other crystal arthropathies
0.000 0.321 0.679
I24.8 Other forms of acute ischaemic heart disease
0.000 0.323 0.677
D04.7 Skin of lower limb, including hip
0.000 0.323 0.677
K72.1 Chronic hepatic failure
0.000 0.324 0.676
N04.8 Other
0.000 0.324 0.676
N04.7 Diffuse crescentic glomerulonephritis
0.000 0.324 0.676
N04.6 Dense deposit disease
0.000 0.324 0.676
N04.5 Diffuse mesangiocapillary glomerulonephritis
0.000 0.324 0.676
N04.4 Diffuse endocapillary proliferative glomerulonephritis
0.000 0.324 0.676
N04.3 Diffuse mesangial proliferative glomerulonephritis
0.000 0.324 0.676
N04.0 Minor glomerular abnormality
0.000 0.324 0.676
L40.4 Guttate psoriasis
0.000 0.324 0.676
E25 Adrenogenital disorders
0.000 0.325 0.675
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.326 0.674
H35 Other retinal disorders
0.000 0.326 0.674
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.327 0.673
E13.3 With ophthalmic complications
0.000 0.327 0.673
J45.8 Mixed asthma
0.000 0.327 0.673
I25.6 Silent myocardial ischaemia
0.000 0.329 0.671
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.329 0.670
M06.38 Rheumatoid nodule (Other)
0.000 0.329 0.670
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.329 0.670
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.329 0.670
M06.33 Rheumatoid nodule (Forearm)
0.000 0.329 0.670
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.329 0.670
M20-M25 Other joint disorders
0.000 0.330 0.670
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.332 0.668
E40-E46 Malnutrition
0.000 0.332 0.668
L44 Other papulosquamous disorders
0.000 0.333 0.667
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.333 0.667
K74.3 Primary biliary cirrhosis
0.000 0.333 0.667
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.333 0.667
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.333 0.667
J98.6 Disorders of diaphragm
0.000 0.334 0.666
C17 Malignant neoplasm of small intestine
0.000 0.335 0.665
M35 Other systemic involvement of connective tissue
0.000 0.337 0.663
C62 Malignant neoplasm of testis
0.000 0.337 0.663
G70 Myasthenia gravis and other myoneural disorders
0.000 0.338 0.662
K86.1 Other chronic pancreatitis
0.000 0.338 0.662
M31 Other necrotising vasculopathies
0.000 0.338 0.662
G64 Other disorders of peripheral nervous system
0.000 0.339 0.661
H31.0 Chorioretinal scars
0.000 0.340 0.660
M35.3 Polymyalgia rheumatica
0.000 0.340 0.660
C22.7 Other specified carcinomas of liver
0.000 0.340 0.659
C22.4 Other sarcomas of liver
0.000 0.340 0.659
C22.3 Angiosarcoma of liver
0.000 0.340 0.659
C22.2 Hepatoblastoma
0.000 0.340 0.659
M31.6 Other giant cell arteritis
0.000 0.343 0.657
I22 Subsequent myocardial infarction
0.000 0.343 0.657
K90.8 Other intestinal malabsorption
0.000 0.343 0.657

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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