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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs11756897
log Bayes Factor = 57.786
Chromosome 6   position 32,899,139  (GRCh37) Explore rs11756897 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10.1 With ketoacidosis
1.000 0.000 0.000
E10.4 With neurological complications
0.999 0.001 0.000
E10-E14 Diabetes mellitus
0.999 0.001 0.000
M06.9 Rheumatoid arthritis, unspecified
0.999 0.001 0.000
E14 Unspecified diabetes mellitus
0.987 0.013 0.000
H36.0 Diabetic retinopathy
0.984 0.016 0.000
M06 Other rheumatoid arthritis
0.981 0.019 0.000
E10.5 With peripheral circulatory complications
0.980 0.020 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.980 0.020 0.000
M05-M14 Inflammatory polyarthropathies
0.971 0.029 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.968 0.032 0.000
M05 Seropositive rheumatoid arthritis
0.967 0.033 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.966 0.034 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.964 0.036 0.000
E11 Non-insulin-dependent diabetes mellitus
0.962 0.038 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.957 0.043 0.000
E14.9 Without complications
0.949 0.051 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.936 0.064 0.000
E10.0 With coma
0.934 0.066 0.000
E10.2 With renal complications
0.919 0.081 0.000
E14.3 With ophthalmic complications
0.913 0.087 0.000
E10.8 With unspecified complications
0.909 0.091 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.900 0.100 0.000
E11.3 With ophthalmic complications
0.889 0.111 0.000
M14 Arthropathies in other diseases classified elsewhere
0.887 0.113 0.000
E11.5 With peripheral circulatory complications
0.882 0.118 0.000
E10.6 With other specified complications
0.871 0.129 0.000
E16.2 Hypoglycaemia, unspecified
0.869 0.131 0.000
E16 Other disorders of pancreatic internal secretion
0.860 0.139 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.855 0.145 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.852 0.148 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.849 0.151 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.848 0.152 0.000
E14.6 With other specified complications
0.845 0.155 0.000
E10.7 With multiple complications
0.842 0.158 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.834 0.166 0.000
M14.6 Neuropathic arthropathy
0.826 0.174 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.819 0.181 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.810 0.190 0.000
M86-M90 Other osteopathies
0.809 0.191 0.000
E11.6 With other specified complications
0.804 0.196 0.000
M86 Osteomyelitis
0.802 0.198 0.000
M06.4 Inflammatory polyarthropathy
0.794 0.206 0.000
M86.9 Osteomyelitis, unspecified
0.785 0.215 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.782 0.218 0.000
M35.3 Polymyalgia rheumatica
0.780 0.220 0.000
E14.8 With unspecified complications
0.778 0.222 0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.776 0.224 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.757 0.243 0.000
M35 Other systemic involvement of connective tissue
0.751 0.249 0.000
M20-M25 Other joint disorders
0.748 0.252 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.741 0.259 0.000
E50-E64 Other nutritional deficiencies
0.732 0.268 0.000
M86.6 Other chronic osteomyelitis
0.718 0.282 0.000
E12 Malnutrition-related diabetes mellitus
0.716 0.284 0.000
M08 Juvenile arthritis
0.715 0.285 0.000
E14.7 With multiple complications
0.708 0.292 0.000
E14.2 Withrenal complications
0.708 0.292 0.000
E14.0 With coma
0.708 0.292 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.707 0.293 0.000
M06.8 Other specified rheumatoid arthritis
0.703 0.297 0.000
M06.2 Rheumatoid bursitis
0.703 0.297 0.000
M06.1 Adult-onset Still's disease
0.703 0.297 0.000
E11.0 With coma
0.701 0.299 0.000
E11.2 With renal complications
0.698 0.302 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.696 0.304 0.000
E61 Deficiency of other nutrient elements
0.694 0.306 0.000
M05.8 Other seropositive rheumatoid arthritis
0.693 0.307 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.693 0.307 0.000
M05.2 Rheumatoid vasculitis
0.693 0.307 0.000
M05.1 Rheumatoid lung disease
0.693 0.307 0.000
M05.0 Felty's syndrome
0.693 0.307 0.000
E14.5 With peripheral circulatory complications
0.691 0.309 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.691 0.309 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.691 0.309 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.691 0.309 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.691 0.309 0.000
E11.7 With multiple complications
0.689 0.310 0.000
E11.1 With ketoacidosis
0.686 0.314 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.685 0.315 0.000
E40-E46 Malnutrition
0.683 0.317 0.000
E13 Other specified diabetes mellitus
0.682 0.318 0.000
M12 Other specific arthropathies
0.681 0.319 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.674 0.326 0.000
E61.1 Iron deficiency
0.672 0.328 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.670 0.330 0.000
M00-M03 Infectious arthropathies
0.664 0.336 0.000
M11 Other crystal arthropathies
0.662 0.338 0.000
M21 Other acquired deformities of limbs
0.652 0.348 0.000
M90 Osteopathies in diseases classified elsewhere
0.652 0.348 0.000
M91-M94 Chondropathies
0.648 0.351 0.000
M70-M79 Other soft tissue disorders
0.645 0.355 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.639 0.361 0.000
M14.8 Arthropathies in other specified diseases classified elsewhere
0.636 0.364 0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.636 0.364 0.000
M14.4 Arthropathy in amyloidosis
0.636 0.364 0.000
M14.3 Lipoid dermatoarthritis
0.636 0.364 0.000
M14.2 Diabetic arthropathy
0.636 0.364 0.000
M14.1 Crystal arthropathy in other metabolic disorders
0.636 0.364 0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.636 0.364 0.000
M60-M63 Disorders of muscles
0.633 0.367 0.000
M75 Shoulder lesions
0.630 0.370 0.000
M31 Other necrotising vasculopathies
0.630 0.370 0.000
M86.96 Osteomyelitis, unspecified (Lower leg)
0.624 0.376 0.000
E11.9 Without complications
0.621 0.379 0.000
M75.4 Impingement syndrome of shoulder
0.621 0.379 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.617 0.383 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.617 0.383 0.000
E16.4 Abnormal secretion of gastrin
0.617 0.383 0.000
E16.3 Increased secretion of glucagon
0.617 0.383 0.000
M65-M68 Disorders of synovium and tendon
0.614 0.386 0.000
E15 Nondiabetic hypoglycaemic coma
0.613 0.387 0.000
M06.3 Rheumatoid nodule
0.609 0.391 0.000
M86.67 Other chronic osteomyelitis (Ankle and foot)
0.609 0.391 0.000
M86.4 Chronic osteomyelitis with draining sinus
0.604 0.395 0.000
M86.94 Osteomyelitis, unspecified (Hand)
0.602 0.398 0.000
E54 Ascorbic acid deficiency
0.599 0.401 0.000
E14.1 With ketoacidosis
0.593 0.407 0.000
E11.8 With unspecified complications
0.593 0.407 0.000
M75.2 Bicipital tendinitis
0.588 0.412 0.000
E11.4 With neurological complications
0.587 0.413 0.000
E14.4 With neurological complications
0.584 0.415 0.000
M86.8 Other osteomyelitis
0.581 0.419 0.000
M32 Systemic lupus erythematosus
0.579 0.421 0.000
M80-M85 Disorders of bone density and structure
0.578 0.422 0.000
M86.69 Other chronic osteomyelitis (Site unspecified)
0.577 0.423 0.000
M86.5 Other chronic haematogenous osteomyelitis
0.575 0.425 0.000
M86.3 Chronic multifocal osteomyelitis
0.575 0.425 0.000
M86.2 Subacute osteomyelitis
0.575 0.425 0.000
M86.1 Other acute osteomyelitis
0.575 0.425 0.000
M86.0 Acute haematogenous osteomyelitis
0.575 0.425 0.000
M21.4 Flat foot [pes planus] (acquired)
0.572 0.428 0.000
M66 Spontaneous rupture of synovium and tendon
0.571 0.429 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.570 0.430 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.570 0.430 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.570 0.430 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.570 0.430 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.570 0.430 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.570 0.430 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.570 0.430 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.570 0.430 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.565 0.435 0.000
M90.7 Fracture of bone in neoplastic disease
0.563 0.437 0.000
M86.93 Osteomyelitis, unspecified (Forearm)
0.563 0.437 0.000
M86.92 Osteomyelitis, unspecified (Upper arm)
0.563 0.437 0.000
M86.91 Osteomyelitis, unspecified (Shoulder region)
0.563 0.437 0.000
M86.90 Osteomyelitis, unspecified (Multiple sites)
0.563 0.437 0.000
E46 Unspecified protein-energy malnutrition
0.561 0.439 0.000
M06.0 Seronegative rheumatoid arthritis
0.560 0.440 0.000
M89 Other disorders of bone
0.560 0.440 0.000
M35.7 Hypermobility syndrome
0.558 0.442 0.000
M86.66 Other chronic osteomyelitis (Lower leg)
0.554 0.446 0.000
M87 Osteonecrosis
0.554 0.446 0.000
M07 Psoriatic and enteropathic arthropathies
0.552 0.448 0.000
M94 Other disorders of cartilage
0.547 0.453 0.000
M88 Paget's disease of bone [osteitis deformans]
0.546 0.454 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.545 0.455 0.000
M00 Pyogenic arthritis
0.543 0.456 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.539 0.461 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.538 0.462 0.000
M35.8 Other specified systemic involvement of connective tissue
0.538 0.462 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.538 0.462 0.000
M35.5 Multifocal fibrosclerosis
0.538 0.462 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.538 0.462 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.537 0.463 0.000
M86.99 Osteomyelitis, unspecified (Site unspecified)
0.534 0.466 0.000
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)
0.532 0.468 0.000
M08.0 Juvenile rheumatoid arthritis
0.532 0.468 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.525 0.475 0.000
E63 Other nutritional deficiencies
0.525 0.475 0.000
E56 Other vitamin deficiencies
0.525 0.475 0.000
E51 Thiamine deficiency
0.525 0.475 0.000
E50 Vitamin A deficiency
0.525 0.475 0.000
E60 Dietary zinc deficiency
0.525 0.475 0.000
E59 Dietary selenium deficiency
0.525 0.475 0.000
E58 Dietary calcium deficiency
0.525 0.475 0.000
E52 Niacin deficiency [pellagra]
0.525 0.475 0.000
M21.2 Flexion deformity
0.523 0.477 0.000
M75.9 Shoulder lesion, unspecified
0.522 0.478 0.000
M21.1 Varus deformity, not elsewhere classified
0.516 0.484 0.000
M86.68 Other chronic osteomyelitis (Other)
0.515 0.485 0.000
M86.65 Other chronic osteomyelitis (Pelvic region and thigh)
0.515 0.485 0.000
M86.64 Other chronic osteomyelitis (Hand)
0.515 0.485 0.000
M86.63 Other chronic osteomyelitis (Forearm)
0.515 0.485 0.000
M86.62 Other chronic osteomyelitis (Upper arm)
0.515 0.485 0.000
M86.61 Other chronic osteomyelitis (Shoulder region)
0.515 0.485 0.000
M86.60 Other chronic osteomyelitis (Multiple sites)
0.515 0.485 0.000
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot
0.514 0.486 0.000
M31.7 Microscopic polyangiitis
0.514 0.486 0.000
E12.9 Without complications
0.513 0.486 0.000
E12.8 With unspecified complications
0.513 0.486 0.000
E12.7 With multiple complications
0.513 0.486 0.000
E12.6 With other specified complications
0.513 0.486 0.000
E12.5 With peripheral circulatory complications
0.513 0.486 0.000
E12.4 With neurological complications
0.513 0.486 0.000
E12.3 With ophthalmic complications
0.513 0.486 0.000
E12.2 With renal complications
0.513 0.486 0.000
E12.1 With ketoacidosis
0.513 0.486 0.000
E12.0 With coma
0.513 0.486 0.000
M08.9 Juvenile arthritis, unspecified
0.513 0.487 0.000
M08.8 Other juvenile arthritis
0.513 0.487 0.000
M08.4 Pauciarticular juvenile arthritis
0.513 0.487 0.000
M08.3 Juvenile polyarthritis (seronegative)
0.513 0.487 0.000
M08.2 Juvenile arthritis with systemic onset
0.513 0.487 0.000
M08.1 Juvenile ankylosing spondylitis
0.513 0.487 0.000
M70.2 Olecranon bursitis
0.511 0.489 0.000
M30 Polyarteritis nodosa and related conditions
0.509 0.491 0.000
M66.2 Spontaneous rupture of extensor tendons
0.509 0.491 0.000
M84 Disorders of continuity of bone
0.509 0.491 0.000
M06.19 Adult-onset Still's disease (Site unspecified)
0.504 0.496 0.000
M06.18 Adult-onset Still's disease (Other)
0.504 0.496 0.000
M06.17 Adult-onset Still's disease (Ankle and foot)
0.504 0.496 0.000
M06.16 Adult-onset Still's disease (Lower leg)
0.504 0.496 0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.504 0.496 0.000
M06.14 Adult-onset Still's disease (Hand)
0.504 0.496 0.000
M06.13 Adult-onset Still's disease (Forearm)
0.504 0.496 0.000
M06.12 Adult-onset Still's disease (Upper arm)
0.504 0.496 0.000
M06.11 Adult-onset Still's disease (Shoulder region)
0.504 0.496 0.000
M06.10 Adult-onset Still's disease (Multiple sites)
0.504 0.496 0.000
M06.29 Rheumatoid bursitis (Site unspecified)
0.504 0.496 0.000
M06.28 Rheumatoid bursitis (Other)
0.504 0.496 0.000
M06.27 Rheumatoid bursitis (Ankle and foot)
0.504 0.496 0.000
M06.26 Rheumatoid bursitis (Lower leg)
0.504 0.496 0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.504 0.496 0.000
M06.24 Rheumatoid bursitis (Hand)
0.504 0.496 0.000
M06.23 Rheumatoid bursitis (Forearm)
0.504 0.496 0.000
M06.22 Rheumatoid bursitis (Upper arm)
0.504 0.496 0.000
M06.21 Rheumatoid bursitis (Shoulder region)
0.504 0.496 0.000
M06.20 Rheumatoid bursitis (Multiple sites)
0.504 0.496 0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.504 0.496 0.000
M06.88 Other specified rheumatoid arthritis (Other)
0.504 0.496 0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.504 0.496 0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.504 0.496 0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.504 0.496 0.000
M06.84 Other specified rheumatoid arthritis (Hand)
0.504 0.496 0.000
M06.83 Other specified rheumatoid arthritis (Forearm)
0.504 0.496 0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.504 0.496 0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.504 0.496 0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.504 0.496 0.000
H36 Retinal disorders in diseases classified elsewhere
0.504 0.496 0.000
M62 Other disorders of muscle
0.502 0.498 0.000
M40-M43 Deforming dorsopathies
0.501 0.499 0.000
M25 Other joint disorders, not elsewhere classified
0.501 0.499 0.000
M35.2 Behcet's disease
0.501 0.499 0.000
M94.8 Other specified disorders of cartilage
0.501 0.499 0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.499 0.500 0.000
M09.2 Juvenile arthritis in ulcerative colitis
0.499 0.500 0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.499 0.500 0.000
M09.0 Juvenile arthritis in psoriasis
0.499 0.500 0.000
E61.9 Deficiency of nutrient element, unspecified
0.497 0.503 0.000
E61.8 Deficiency of other specified nutrient elements
0.497 0.503 0.000
E61.7 Deficiency of multiple nutrient elements
0.497 0.503 0.000
E61.6 Vanadium deficiency
0.497 0.503 0.000
E61.5 Molybdenum deficiency
0.497 0.503 0.000
E61.4 Chromium deficiency
0.497 0.503 0.000
E61.3 Manganese deficiency
0.497 0.503 0.000
E61.0 Copper deficiency
0.497 0.503 0.000
M05.09 Felty's syndrome (Site unspecified)
0.497 0.503 0.000
M05.08 Felty's syndrome (Other)
0.497 0.503 0.000
M05.07 Felty's syndrome (Ankle and foot)
0.497 0.503 0.000
M05.06 Felty's syndrome (Lower leg)
0.497 0.503 0.000
M05.05 Felty's syndrome (Pelvic region and thigh)
0.497 0.503 0.000
M05.04 Felty's syndrome (Hand)
0.497 0.503 0.000
M05.03 Felty's syndrome (Forearm)
0.497 0.503 0.000
M05.02 Felty's syndrome (Upper arm)
0.497 0.503 0.000
M05.01 Felty's syndrome (Shoulder region)
0.497 0.503 0.000
M05.00 Felty's syndrome (Multiple sites)
0.497 0.503 0.000
M05.19 Rheumatoid lung disease (Site unspecified)
0.497 0.503 0.000
M05.18 Rheumatoid lung disease (Other)
0.497 0.503 0.000
M05.17 Rheumatoid lung disease (Ankle and foot)
0.497 0.503 0.000
M05.16 Rheumatoid lung disease (Lower leg)
0.497 0.503 0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.497 0.503 0.000
M05.14 Rheumatoid lung disease (Hand)
0.497 0.503 0.000
M05.13 Rheumatoid lung disease (Forearm)
0.497 0.503 0.000
M05.12 Rheumatoid lung disease (Upper arm)
0.497 0.503 0.000
M05.11 Rheumatoid lung disease (Shoulder region)
0.497 0.503 0.000
M05.10 Rheumatoid lung disease (Multiple sites)
0.497 0.503 0.000
M05.29 Rheumatoid vasculitis (Site unspecified)
0.497 0.503 0.000
M05.28 Rheumatoid vasculitis (Other)
0.497 0.503 0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.497 0.503 0.000
M05.26 Rheumatoid vasculitis (Lower leg)
0.497 0.503 0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)
0.497 0.503 0.000
M05.24 Rheumatoid vasculitis (Hand)
0.497 0.503 0.000
M05.23 Rheumatoid vasculitis (Forearm)
0.497 0.503 0.000
M05.22 Rheumatoid vasculitis (Upper arm)
0.497 0.503 0.000
M05.21 Rheumatoid vasculitis (Shoulder region)
0.497 0.503 0.000
M05.20 Rheumatoid vasculitis (Multiple sites)
0.497 0.503 0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.497 0.503 0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.497 0.503 0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.497 0.503 0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.497 0.503 0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.497 0.503 0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.497 0.503 0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.497 0.503 0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.497 0.503 0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)
0.497 0.503 0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)
0.497 0.503 0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.497 0.503 0.000
M05.88 Other seropositive rheumatoid arthritis (Other)
0.497 0.503 0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.497 0.503 0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.497 0.503 0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.497 0.503 0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.497 0.503 0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.497 0.503 0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.497 0.503 0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.497 0.503 0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.497 0.503 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.495 0.505 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.491 0.508 0.000
M02 Reactive arthropathies
0.491 0.509 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.490 0.510 0.000
E45 Retarded development following protein-energy malnutrition
0.490 0.510 0.000
E43 Unspecified severe protein-energy malnutrition
0.490 0.510 0.000
E42 Marasmic kwashiorkor
0.490 0.510 0.000
E41 Nutritional marasmus
0.490 0.510 0.000
E40 Kwashiorkor
0.490 0.510 0.000
E13.8 With unspecified complications
0.489 0.511 0.000
E13.7 With multiple complications
0.489 0.511 0.000
E13.6 With other specified complications
0.489 0.511 0.000
E13.5 With peripheral circulatory complications
0.489 0.511 0.000
E13.4 With neurological complications
0.489 0.511 0.000
E13.3 With ophthalmic complications
0.489 0.511 0.000
E13.2 With renal complications
0.489 0.511 0.000
E13.1 With ketoacidosis
0.489 0.511 0.000
E13.0 With coma
0.489 0.511 0.000
M12.8 Other specific arthropathies, not elsewhere classified
0.488 0.511 0.000
M12.5 Traumatic arthropathy
0.488 0.511 0.000
M12.4 Intermittent hydrarthrosis
0.488 0.511 0.000
M12.1 Kaschin-Beck disease
0.488 0.511 0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.488 0.511 0.000
M21.7 Unequal limb length (acquired)
0.487 0.513 0.000
M21.9 Acquired deformity of limb, unspecified
0.487 0.513 0.000
M90.78 Fracture of bone in neoplastic disease (Other)
0.486 0.514 0.000
M31.8 Other specified necrotising vasculopathies
0.483 0.517 0.000
M12.2 Villonodular synovitis (pigmented)
0.481 0.519 0.000
M12.3 Palindromic rheumatism
0.480 0.519 0.000
M89.0 Algoneurodystrophy
0.481 0.519 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.479 0.521 0.000
M11.9 Crystal arthropathy, unspecified
0.479 0.521 0.000
M70.4 Prepatellar bursitis
0.478 0.522 0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere
0.476 0.524 0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere
0.476 0.524 0.000
M11.8 Other specified crystal arthropathies
0.474 0.525 0.000
M11.1 Familial chondrocalcinosis
0.474 0.525 0.000
M11.0 Hydroxyapatite deposition disease
0.474 0.525 0.000
M75.5 Bursitis of shoulder
0.475 0.525 0.000
M33 Dermatopolymyositis
0.473 0.527 0.000
M66.5 Spontaneous rupture of unspecified tendon
0.472 0.527 0.000
M90.8 Osteopathy in other diseases classified elsewhere
0.467 0.532 0.000
M90.6 Osteitis deformans in neoplastic disease
0.467 0.532 0.000
M90.5 Osteonecrosis in other diseases classified elsewhere
0.467 0.532 0.000
M90.4 Osteonecrosis due to heamoglobinopathy
0.467 0.532 0.000
M90.3 Osteonecrosis in caisson disease
0.467 0.532 0.000
M90.2 Osteopathy in other infectious diseases classified elsewhere
0.467 0.532 0.000
M90.0 Tuberculosis of bone
0.467 0.532 0.000
M66.24 Spontaneous rupture of extensor tendons (Hand)
0.465 0.535 0.000
M86.47 Chronic osteomyelitis with draining sinus (Ankle and foot)
0.463 0.537 0.000
M93 Other osteochondropathies
0.462 0.537 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.462 0.538 0.000
M21.6 Other acquired deformities of ankle and foot
0.462 0.538 0.000
M00.9 Pyogenic arthritis, unspecified
0.457 0.543 0.000
M92 Other juvenile osteochondrosis
0.457 0.543 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.457 0.543 0.000
M75.3 Calcific tendinitis of shoulder
0.456 0.544 0.000
M86.86 Other osteomyelitis (Lower leg)
0.455 0.545 0.000
E13.9 Without complications
0.455 0.545 0.000
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)
0.454 0.546 0.000
M21.8 Other specified acquired deformities of limbs
0.454 0.546 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.454 0.546 0.000
M61 Calcification and ossification of muscle
0.454 0.546 0.000
M94.86 Other specified disorders of cartilage (Lower leg)
0.453 0.547 0.000
M66.3 Spontaneous rupture of flexor tendons
0.452 0.548 0.000
M75.8 Other shoulder lesions
0.452 0.548 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.452 0.548 0.000
M31.2 Lethal midline granuloma
0.452 0.548 0.000
M31.1 Thrombotic microangiopathy
0.452 0.548 0.000
M31.0 Hypersensitivity angiitis
0.452 0.548 0.000
M71 Other bursopathies
0.451 0.549 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.451 0.549 0.000
E61.2 Magnesium deficiency
0.450 0.550 0.000
M60 Myositis
0.450 0.550 0.000
M70.22 Olecranon bursitis-Upper arm
0.449 0.551 0.000
M31.9 Necrotising vasculopathy, unspecified
0.444 0.556 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.440 0.560 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.440 0.560 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.439 0.561 0.000
M89.04 Algoneurodystrophy (Hand)
0.438 0.562 0.000
M25.4 Effusion of joint
0.438 0.562 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.437 0.563 0.000
M06.38 Rheumatoid nodule (Other)
0.437 0.563 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.437 0.563 0.000
M06.33 Rheumatoid nodule (Forearm)
0.437 0.563 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.437 0.563 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.437 0.563 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.436 0.564 0.000
M35.1 Other overlap syndromes
0.435 0.565 0.000
M21.24 Flexion deformity (Hand)
0.435 0.565 0.000
E16.1 Other hypoglycaemia
0.435 0.565 0.001
M11.2 Other chondrocalcinosis
0.434 0.566 0.000
M86.49 Chronic osteomyelitis with draining sinus (Site unspecified)
0.433 0.566 0.000
M86.48 Chronic osteomyelitis with draining sinus (Other)
0.433 0.566 0.000
M86.46 Chronic osteomyelitis with draining sinus (Lower leg)
0.433 0.566 0.000
M86.45 Chronic osteomyelitis with draining sinus (Pelvic region and thigh)
0.433 0.566 0.000
M86.44 Chronic osteomyelitis with draining sinus (Hand)
0.433 0.566 0.000
M86.43 Chronic osteomyelitis with draining sinus (Forearm)
0.433 0.566 0.000
M86.42 Chronic osteomyelitis with draining sinus (Upper arm)
0.433 0.566 0.000
M86.41 Chronic osteomyelitis with draining sinus (Shoulder region)
0.433 0.566 0.000
M86.40 Chronic osteomyelitis with draining sinus (Multiple sites)
0.433 0.566 0.000
M89.3 Hypertrophy of bone
0.433 0.567 0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)
0.433 0.567 0.000
M90.70 Fracture of bone in neoplastic disease (Multiple sites)
0.432 0.568 0.000
M87.2 Osteonecrosis due to previous trauma
0.431 0.569 0.000
M86.98 Osteomyelitis, unspecified (Other)
0.427 0.572 0.000
M34 Systemic sclerosis
0.425 0.574 0.000
M83 Adult osteomalacia
0.422 0.578 0.000
M70.23 Olecranon bursitis-Forearm
0.422 0.578 0.000
M21.22 Flexion deformity (Upper arm)
0.421 0.579 0.000
M90.71 Fracture of bone in neoplastic disease (Shoulder region)
0.419 0.581 0.000
M90.1 Periostitis in other infectious diseases classified elsewhere
0.417 0.582 0.000
M70.46 Prepatellar bursitis-Lower Leg
0.416 0.583 0.000
M86.89 Other osteomyelitis (Site unspecified)
0.416 0.584 0.000
M86.88 Other osteomyelitis (Other)
0.416 0.584 0.000
M86.85 Other osteomyelitis (Pelvic region and thigh)
0.416 0.584 0.000
M86.84 Other osteomyelitis (Hand)
0.416 0.584 0.000
M86.83 Other osteomyelitis (Forearm)
0.416 0.584 0.000
M86.82 Other osteomyelitis (Upper arm)
0.416 0.584 0.000
M86.81 Other osteomyelitis (Shoulder region)
0.416 0.584 0.000
M86.80 Other osteomyelitis (Multiple sites)
0.416 0.584 0.000
M94.89 Other specified disorders of cartilage (Site unspecified)
0.416 0.584 0.000
M32.9 Systemic lupus erythematosus, unspecified
0.415 0.585 0.000
M32.8 Other forms of systemic lupus erythematosus
0.415 0.585 0.000
M32.0 Drug-induced systemic lupus erythematosus
0.415 0.585 0.000
M66.4 Spontaneous rupture of other tendons
0.414 0.586 0.000
M86.09 Acute haematogenous osteomyelitis (Site unspecified)
0.412 0.587 0.000
M86.08 Acute haematogenous osteomyelitis (Other)
0.412 0.587 0.000
M86.07 Acute haematogenous osteomyelitis (Ankle and foot)
0.412 0.587 0.000
M86.06 Acute haematogenous osteomyelitis (Lower leg)
0.412 0.587 0.000
M86.05 Acute haematogenous osteomyelitis (Pelvic region and thigh)
0.412 0.587 0.000
M86.04 Acute haematogenous osteomyelitis (Hand)
0.412 0.587 0.000
M86.03 Acute haematogenous osteomyelitis (Forearm)
0.412 0.587 0.000
M86.02 Acute haematogenous osteomyelitis (Upper arm)
0.412 0.587 0.000
M86.01 Acute haematogenous osteomyelitis (Shoulder region)
0.412 0.587 0.000
M86.00 Acute haematogenous osteomyelitis (Multiple sites)
0.412 0.587 0.000
M86.19 Other acute osteomyelitis (Site unspecified)
0.412 0.587 0.000
M86.18 Other acute osteomyelitis (Other)
0.412 0.587 0.000
M86.17 Other acute osteomyelitis (Ankle and foot)
0.412 0.587 0.000
M86.16 Other acute osteomyelitis (Lower leg)
0.412 0.587 0.000
M86.15 Other acute osteomyelitis (Pelvic region and thigh)
0.412 0.587 0.000
M86.14 Other acute osteomyelitis (Hand)
0.412 0.587 0.000
M86.13 Other acute osteomyelitis (Forearm)
0.412 0.587 0.000
M86.12 Other acute osteomyelitis (Upper arm)
0.412 0.587 0.000
M86.11 Other acute osteomyelitis (Shoulder region)
0.412 0.587 0.000
M86.10 Other acute osteomyelitis (Multiple sites)
0.412 0.587 0.000
M86.29 Subacute osteomyelitis (Site unspecified)
0.412 0.587 0.000
M86.28 Subacute osteomyelitis (Other)
0.412 0.587 0.000
M86.27 Subacute osteomyelitis (Ankle and foot)
0.412 0.587 0.000
M86.26 Subacute osteomyelitis (Lower leg)
0.412 0.587 0.000
M86.25 Subacute osteomyelitis (Pelvic region and thigh)
0.412 0.587 0.000
M86.24 Subacute osteomyelitis (Hand)
0.412 0.587 0.000
M86.23 Subacute osteomyelitis (Forearm)
0.412 0.587 0.000
M86.22 Subacute osteomyelitis (Upper arm)
0.412 0.587 0.000
M86.21 Subacute osteomyelitis (Shoulder region)
0.412 0.587 0.000
M86.20 Subacute osteomyelitis (Multiple sites)
0.412 0.587 0.000
M86.39 Chronic multifocal osteomyelitis (Site unspecified)
0.412 0.587 0.000
M86.38 Chronic multifocal osteomyelitis (Other)
0.412 0.587 0.000
M86.37 Chronic multifocal osteomyelitis (Ankle and foot)
0.412 0.587 0.000
M86.36 Chronic multifocal osteomyelitis (Lower leg)
0.412 0.587 0.000
M86.35 Chronic multifocal osteomyelitis (Pelvic region and thigh)
0.412 0.587 0.000
M86.34 Chronic multifocal osteomyelitis (Hand)
0.412 0.587 0.000
M86.33 Chronic multifocal osteomyelitis (Forearm)
0.412 0.587 0.000
M86.32 Chronic multifocal osteomyelitis (Upper arm)
0.412 0.587 0.000
M86.31 Chronic multifocal osteomyelitis (Shoulder region)
0.412 0.587 0.000
M86.30 Chronic multifocal osteomyelitis (Multiple sites)
0.412 0.587 0.000
M86.59 Other chronic haematogenous osteomyelitis (Site unspecified)
0.412 0.587 0.000
M86.58 Other chronic haematogenous osteomyelitis (Other)
0.412 0.587 0.000
M86.57 Other chronic haematogenous osteomyelitis (Ankle and foot)
0.412 0.587 0.000
M86.56 Other chronic haematogenous osteomyelitis (Lower leg)
0.412 0.587 0.000
M86.55 Other chronic haematogenous osteomyelitis (Pelvic region and thigh)
0.412 0.587 0.000
M86.54 Other chronic haematogenous osteomyelitis (Hand)
0.412 0.587 0.000
M86.53 Other chronic haematogenous osteomyelitis (Forearm)
0.412 0.587 0.000
M86.52 Other chronic haematogenous osteomyelitis (Upper arm)
0.412 0.587 0.000
M86.51 Other chronic haematogenous osteomyelitis (Shoulder region)
0.412 0.587 0.000
M86.50 Other chronic haematogenous osteomyelitis (Multiple sites)
0.412 0.587 0.000
M21.49 Flat foot [pes planus] (acquired)-Site unspec
0.410 0.590 0.000
M21.48 Flat foot [pes planus] (acquired)-Other
0.410 0.590 0.000
M21.46 Flat foot [pes planus] (acquired)-Lower leg
0.410 0.590 0.000
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh
0.410 0.590 0.000
M21.44 Flat foot [pes planus] (acquired)-Hand
0.410 0.590 0.000
M21.43 Flat foot [pes planus] (acquired)-Forearm
0.410 0.590 0.000
M21.42 Flat foot [pes planus] (acquired)-Upper arm
0.410 0.590 0.000
M21.41 Flat foot [pes planus] (acquired)-Shldr region
0.410 0.590 0.000
M21.40 Flat foot [pes planus] (acquired)-Mult sites
0.410 0.590 0.000
M21.0 Valgus deformity, not elsewhere classified
0.410 0.590 0.000
M66.1 Rupture of synovium
0.409 0.591 0.000
M25.3 Other instability of joint
0.408 0.592 0.000
M25.0 Haemarthrosis
0.405 0.595 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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