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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3129961
log Bayes Factor = 181.164
Chromosome 6   position 32,378,940  (GRCh37) Explore rs3129961 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
J33 Nasal polyp
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
J30-J39 Other diseases of upper respiratory tract
0.000 0.000 1.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.001 0.999
E14.3 With ophthalmic complications
0.000 0.001 0.999
L40 Psoriasis
0.000 0.001 0.999
# Top node
0.000 0.001 0.999
E10.4 With neurological complications
0.000 0.001 0.999
Chapter X Diseases of the respiratory system
0.000 0.001 0.999
L40-L45 Papulosquamous disorders
0.000 0.001 0.999
J33.9 Nasal polyp, unspecified
0.000 0.002 0.998
L40.9 Psoriasis, unspecified
0.000 0.002 0.998
J40-J47 Chronic lower respiratory diseases
0.000 0.003 0.997
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.003 0.997
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.004 0.996
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.006 0.994
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.000 0.009 0.991
L40.5 Arthropathic psoriasis
0.000 0.009 0.991
J33.8 Other polyp of sinus
0.000 0.009 0.991
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.009 0.991
J43 Emphysema
0.000 0.014 0.986
H36 Retinal disorders in diseases classified elsewhere
0.000 0.014 0.986
E10.5 With peripheral circulatory complications
0.000 0.016 0.984
E14.9 Without complications
0.000 0.016 0.984
J32 Chronic sinusitis
0.000 0.018 0.982
G35-G37 Demyelinating diseases of the central nervous system
0.982 0.018 0.000
G37 Other demyelinating diseases of central nervous system
0.979 0.021 0.000
Chapter VII Diseases of the eye and adnexa
0.000 0.022 0.978
M20-M25 Other joint disorders
0.000 0.024 0.976
H30-H36 Disorders of choroid and retina
0.000 0.025 0.975
L43 Lichen planus
0.000 0.025 0.975
G37.9 Demyelinating disease of central nervous system, unspecified
0.974 0.026 0.000
J43.9 Emphysema, unspecified
0.000 0.026 0.974
M35.3 Polymyalgia rheumatica
0.000 0.027 0.973
M35 Other systemic involvement of connective tissue
0.000 0.027 0.973
Chapter VIII Diseases of the ear and mastoid process
0.000 0.029 0.971
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.030 0.970
J46 Status asthmaticus
0.000 0.030 0.970
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.032 0.968
E10.2 With renal complications
0.000 0.034 0.966
J38.3 Other diseases of vocal cords
0.000 0.034 0.966
J32.9 Chronic sinusitis, unspecified
0.000 0.035 0.965
M06.3 Rheumatoid nodule
0.000 0.035 0.965
M25.46 Effusion of joint (Lower leg)
0.000 0.040 0.960
J44 Other chronic obstructive pulmonary disease
0.000 0.043 0.957
L43.9 Lichen planus, unspecified
0.000 0.043 0.957
M25.4 Effusion of joint
0.000 0.043 0.957
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.045 0.955
M25 Other joint disorders, not elsewhere classified
0.000 0.045 0.955
H43-H45 Disorders of vitreous body and globe
0.000 0.046 0.954
M06.0 Seronegative rheumatoid arthritis
0.000 0.047 0.953
J38.0 Paralysis of vocal cords and larynx
0.000 0.053 0.947
H25-H28 Disorders of lens
0.000 0.054 0.946
H60-H62 Diseases of external ear
0.000 0.057 0.943
H43 Disorders of vitreous body
0.000 0.065 0.935
H90-H95 Other disorders of ear
0.000 0.065 0.935
H91 Other hearing loss
0.000 0.073 0.927
M31 Other necrotising vasculopathies
0.000 0.073 0.927
H91.9 Hearing loss, unspecified
0.000 0.079 0.921
K90 Intestinal malabsorption
0.000 0.079 0.921
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.081 0.919
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.081 0.919
M65-M68 Disorders of synovium and tendon
0.000 0.081 0.919
M31.6 Other giant cell arteritis
0.000 0.082 0.918
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.084 0.916
E10.0 With coma
0.000 0.084 0.916
E11.1 With ketoacidosis
0.000 0.088 0.912
M07 Psoriatic and enteropathic arthropathies
0.000 0.089 0.911
E10.8 With unspecified complications
0.000 0.089 0.911
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.093 0.907
H27 Other disorders of lens
0.000 0.093 0.907
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.094 0.906
K90-K93 Other diseases of the digestive system
0.000 0.097 0.903
C83.3 Large cell (diffuse)
0.000 0.097 0.903
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.099 0.901
H25.1 Senile nuclear cataract
0.000 0.099 0.901
E06 Thyroiditis
0.000 0.099 0.901
Chapter XI Diseases of the digestive system
0.000 0.100 0.900
H25 Senile cataract
0.000 0.100 0.900
M06.34 Rheumatoid nodule (Hand)
0.000 0.101 0.899
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.102 0.898
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.102 0.898
E10.6 With other specified complications
0.000 0.106 0.894
E11.3 With ophthalmic complications
0.000 0.107 0.893
H60 Otitis externa
0.000 0.108 0.892
E40-E46 Malnutrition
0.000 0.110 0.890
M65 Synovitis and tenosynovitis
0.000 0.110 0.890
K70-K77 Diseases of liver
0.000 0.111 0.889
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.127 0.873
K74 Fibrosis and cirrhosis of liver
0.000 0.133 0.867
K74.3 Primary biliary cirrhosis
0.000 0.138 0.862
H43.3 Other vitreous opacities
0.000 0.138 0.862
L40.0 Psoriasis vulgaris
0.000 0.146 0.854
H27.0 Aphakia
0.000 0.147 0.853
E06.3 Autoimmune thyroiditis
0.000 0.150 0.850
E11.5 With peripheral circulatory complications
0.000 0.151 0.849
E13 Other specified diabetes mellitus
0.000 0.152 0.848
M07.3 Other psoriatic arthropathies
0.000 0.153 0.847
E07 Other disorders of thyroid
0.000 0.157 0.843
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.157 0.843
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.157 0.843
G37.8 Other specified demyelinating diseases of central nervous system
0.843 0.157 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.158 0.842
H61 Other disorders of external ear
0.000 0.162 0.838
J32.4 Chronic pansinusitis
0.000 0.162 0.838
K73 Chronic hepatitis, not elsewhere classified
0.000 0.163 0.837
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.000 0.172 0.828
M06.4 Inflammatory polyarthropathy
0.000 0.175 0.825
H43.8 Other disorders of vitreous body
0.000 0.176 0.824
J37 Chronic laryngitis and laryngotracheitis
0.000 0.177 0.823
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.179 0.821
E14.8 With unspecified complications
0.000 0.189 0.811
E46 Unspecified protein-energy malnutrition
0.000 0.189 0.811
M25.6 Stiffness of joint, not elsewhere classified
0.000 0.190 0.810
D86.0 Sarcoidosis of lung
0.810 0.190 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.000 0.191 0.809
M35.1 Other overlap syndromes
0.000 0.191 0.809
J38.1 Polyp of vocal cord and larynx
0.000 0.192 0.808
C85.1 B-cell lymphoma, unspecified
0.000 0.193 0.807
E11.8 With unspecified complications
0.000 0.194 0.806
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.195 0.805
H43.1 Vitreous haemorrhage
0.000 0.195 0.805
H27.8 Other specified disorders of lens
0.000 0.195 0.805
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.202 0.798
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.203 0.797
J38.6 Stenosis of larynx
0.000 0.205 0.795
E03.8 Other specified hypothyroidism
0.000 0.206 0.794
E14.5 With peripheral circulatory complications
0.000 0.214 0.785
L00-L08 Infections of the skin and subcutaneous tissue
0.000 0.216 0.784
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.217 0.783
E11.0 With coma
0.000 0.219 0.781
M25.40 Effusion of joint (Multiple sites)
0.000 0.221 0.779
K50-K52 Noninfective enteritis and colitis
0.014 0.221 0.764
H40-H42 Glaucoma
0.000 0.223 0.777
D86 Sarcoidosis
0.774 0.225 0.000
E14.1 With ketoacidosis
0.000 0.228 0.772
J43.2 Centrilobular emphysema
0.000 0.228 0.772
M34 Systemic sclerosis
0.000 0.229 0.771
J33.1 Polypoid sinus degeneration
0.000 0.229 0.771
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.231 0.769
E16.1 Other hypoglycaemia
0.000 0.232 0.768
Chapter II Neoplasms
0.000 0.233 0.767
E11.2 With renal complications
0.000 0.234 0.766
J38.4 Oedema of larynx
0.000 0.235 0.765
C82.0 Small cleaved cell, follicular
0.000 0.238 0.762
J32.2 Chronic ethmoidal sinusitis
0.000 0.238 0.762
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.239 0.761
C91 Lymphoid leukaemia
0.000 0.240 0.760
H60.3 Other infective otitis externa
0.000 0.240 0.760
M14 Arthropathies in other diseases classified elsewhere
0.000 0.242 0.758
J86 Pyothorax
0.000 0.243 0.757
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.000 0.245 0.755
M60-M63 Disorders of muscles
0.000 0.246 0.754
H30 Chorioretinal inflammation
0.000 0.247 0.753
K76 Other diseases of liver
0.000 0.248 0.752
J33.0 Polyp of nasal cavity
0.000 0.252 0.748
E07.9 Disorder of thyroid, unspecified
0.000 0.252 0.748
K73.9 Chronic hepatitis, unspecified
0.000 0.253 0.747
J41 Simple and mucopurulent chronic bronchitis
0.000 0.253 0.747
H60.5 Acute otitis externa, non-infective
0.000 0.253 0.747
J32.8 Other chronic sinusitis
0.000 0.253 0.747
J43.8 Other emphysema
0.000 0.253 0.747
K76.8 Other specified diseases of liver
0.000 0.255 0.745
H60.4 Cholesteatoma of external ear
0.000 0.255 0.745
M25.43 Effusion of joint (Forearm)
0.000 0.256 0.744
D86.9 Sarcoidosis, unspecified
0.744 0.256 0.000
H61.8 Other specified disorders of external ear
0.000 0.256 0.744
H60.1 Cellulitis of external ear
0.000 0.257 0.743
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.257 0.743
C02 Malignant neoplasm of other and unspecified parts of tongue
0.000 0.258 0.742
K50 Crohn's disease [regional enteritis]
0.000 0.259 0.741
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.259 0.741
E11.6 With other specified complications
0.000 0.260 0.739
M25.0 Haemarthrosis
0.000 0.261 0.739
E13.9 Without complications
0.000 0.261 0.739
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.000 0.262 0.738
H91.1 Presbycusis
0.000 0.265 0.735
L50-L54 Urticaria and erythema
0.000 0.267 0.733
H43.2 Crystalline deposits in vitreous body
0.000 0.269 0.731
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.273 0.727
M31.9 Necrotising vasculopathy, unspecified
0.000 0.274 0.726
M25.64 Stiffness of joint, not elsewhere classified (Hand)
0.000 0.275 0.725
C82.2 Large cell, follicular
0.000 0.275 0.724
C95 Leukaemia of unspecified cell type
0.000 0.276 0.724
M65.8 Other synovitis and tenosynovitis
0.000 0.277 0.723
E14.4 With neurological complications
0.000 0.278 0.722
L10-L14 Bullous disorders
0.000 0.280 0.720
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.282 0.718
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.6 With other specified complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.716
L40.2 Acrodermatitis continua
0.000 0.283 0.716
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.284 0.716
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.284 0.716
L44 Other papulosquamous disorders
0.000 0.284 0.716
L41 Parapsoriasis
0.000 0.284 0.716
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.284 0.716
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)
0.000 0.284 0.716
C82.3 Follicular lymphoma grade IIIa
0.000 0.290 0.710
M25.42 Effusion of joint (Upper arm)
0.000 0.291 0.709
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.000 0.292 0.708
J45 Asthma
0.000 0.293 0.707
J43.1 Panlobular emphysema
0.000 0.293 0.707
J43.0 MacLeod's syndrome
0.000 0.293 0.707
K50.8 Other Crohn's disease
0.000 0.293 0.707
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.293 0.707
L43.8 Other lichen planus
0.000 0.298 0.702
G37.5 Concentric sclerosis [Balo]
0.702 0.298 0.000
G37.4 Subacute necrotising myelitis
0.702 0.298 0.000
G37.2 Central pontine myelinolysis
0.702 0.298 0.000
G37.1 Central demyelination of corpus callosum
0.702 0.298 0.000
G37.0 Diffuse sclerosis
0.702 0.298 0.000
C02.9 Tongue, unspecified
0.000 0.300 0.700
H61.3 Acquired stenosis of external ear canal
0.000 0.300 0.700
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.301 0.699
L43.3 Subacute (active) lichen planus
0.000 0.301 0.699
L43.2 Lichenoid drug reaction
0.000 0.301 0.699
L43.1 Bullous lichen planus
0.000 0.301 0.699
L43.0 Hypertrophic lichen planus
0.000 0.301 0.699
H44 Disorders of globe
0.000 0.301 0.698
L40.1 Generalised pustular psoriasis
0.000 0.302 0.698
M12 Other specific arthropathies
0.000 0.302 0.698
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.302 0.697
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.302 0.697
M35.5 Multifocal fibrosclerosis
0.000 0.302 0.697
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.302 0.697
C45 Mesothelioma
0.000 0.303 0.697
J37.0 Chronic laryngitis
0.000 0.304 0.696
L03 Cellulitis
0.000 0.305 0.695
L40.3 Pustulosis palmaris et plantaris
0.000 0.305 0.695
C91.1 Chronic lymphocytic leukaemia
0.000 0.305 0.695
L03.0 Cellulitis of finger and toe
0.000 0.307 0.693
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.000 0.307 0.693
M10 Gout
0.000 0.308 0.692
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.308 0.692
M06.38 Rheumatoid nodule (Other)
0.000 0.308 0.692
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.308 0.692
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.308 0.692
M06.33 Rheumatoid nodule (Forearm)
0.000 0.308 0.692
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.308 0.692
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.308 0.692
M06.8 Other specified rheumatoid arthritis
0.000 0.308 0.692
C02.1 Border of tongue
0.000 0.308 0.692
M25.45 Effusion of joint (Pelvic region and thigh)
0.000 0.308 0.691
H91.2 Sudden idiopathic hearing loss
0.000 0.309 0.691
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.687 0.313 0.000
J32.1 Chronic frontal sinusitis
0.000 0.313 0.687
M25.49 Effusion of joint (Site unspecified)
0.000 0.314 0.686
M25.48 Effusion of joint (Other)
0.000 0.314 0.686
M25.2 Flail joint
0.000 0.315 0.685
M25.1 Fistula of joint
0.000 0.315 0.685
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.316 0.684
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.316 0.684
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.316 0.684
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.316 0.684
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.316 0.684
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.316 0.684
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.316 0.684
H34 Retinal vascular occlusions
0.000 0.316 0.683
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.317 0.683
E03.1 Congenital hypothyroidism without goitre
0.000 0.318 0.682
C82.4 Follicular lymphoma grade IIIb
0.000 0.318 0.682
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.320 0.679
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.000 0.322 0.678
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.323 0.677
G36 Other acute disseminated demyelination
0.677 0.323 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.000 0.324 0.676
C83.1 Small cleaved cell (diffuse)
0.000 0.325 0.675
M60 Myositis
0.000 0.328 0.672
H43.0 Vitreous prolapse
0.000 0.329 0.671
H94 Other disorders of ear in diseases classified elsewhere
0.000 0.330 0.670
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)
0.000 0.330 0.670
L02 Cutaneous abscess, furuncle and carbuncle
0.000 0.335 0.665
H91.0 Ototoxic hearing loss
0.000 0.335 0.664
M31.8 Other specified necrotising vasculopathies
0.000 0.336 0.664
M31.7 Microscopic polyangiitis
0.000 0.336 0.664
M31.4 Aortic arch syndrome [Takayasu]
0.000 0.336 0.664
M31.2 Lethal midline granuloma
0.000 0.336 0.664
M65.86 Other synovitis and tenosynovitis (Lower leg)
0.000 0.336 0.664
K75 Other inflammatory liver diseases
0.000 0.338 0.662
J86.0 Pyothorax with fistula
0.000 0.338 0.662
C82.1 Mixed small cleaved and large cell, follicular
0.000 0.338 0.662
H61.1 Non-infective disorders of pinna
0.000 0.339 0.661
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.339 0.661
K90.3 Pancreatic steatorrhoea
0.000 0.339 0.660
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.339 0.660
K90.1 Tropical sprue
0.000 0.339 0.660
C82.6 Cutaneous follicle centre lymphoma
0.000 0.341 0.659
C82.5 Diffuse follicle centre lymphoma
0.000 0.341 0.659
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.341 0.659
K50.1 Crohn's disease of large intestine
0.000 0.342 0.658
M25.41 Effusion of joint (Shoulder region)
0.000 0.343 0.657
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.343 0.657
D86.1 Sarcoidosis of lymph nodes
0.656 0.343 0.000
M30 Polyarteritis nodosa and related conditions
0.000 0.344 0.656
E11.4 With neurological complications
0.000 0.345 0.655
M66 Spontaneous rupture of synovium and tendon
0.000 0.345 0.655
K51.9 Ulcerative colitis, unspecified
0.653 0.347 0.000
M07.6 Other enteropathic arthropathies
0.000 0.347 0.653
M07.5 Arthropathy in ulcerative colitis
0.000 0.347 0.653
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.347 0.653
M07.2 Psoriatic spondylitis
0.000 0.347 0.653
M07.1 Arthritis mutilans
0.000 0.347 0.653
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.347 0.653
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.000 0.347 0.653
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.349 0.650
H27.9 Disorder of lens, unspecified
0.000 0.350 0.650
K72 Hepatic failure, not elsewhere classified
0.000 0.350 0.649
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.000 0.352 0.648
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.352 0.648
E06.5 Other chronic thyroiditis
0.000 0.354 0.646
E06.4 Drug-induced thyroiditis
0.000 0.354 0.646
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.354 0.646
E06.0 Acute thyroiditis
0.000 0.354 0.646
H25.2 Senile cataract, morgagnian type
0.000 0.355 0.645
C45.9 Mesothelioma, unspecified
0.000 0.356 0.644
C83.6 Undifferentiated (diffuse)
0.000 0.356 0.644
C83.5 Lymphoblastic (diffuse)
0.000 0.356 0.644
C83.4 Immunoblastic (diffuse)
0.000 0.356 0.644
C83.2 Mixed small and large cell (diffuse)
0.000 0.356 0.644
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.357 0.643
K90.9 Intestinal malabsorption, unspecified
0.000 0.360 0.640
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.360 0.640
H60.2 Malignant otitis externa
0.000 0.360 0.640
H43.9 Disorder of vitreous body, unspecified
0.000 0.361 0.639
H60.0 Abscess of external ear
0.000 0.362 0.638
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.362 0.638
E45 Retarded development following protein-energy malnutrition
0.000 0.362 0.638
E43 Unspecified severe protein-energy malnutrition
0.000 0.362 0.638
E42 Marasmic kwashiorkor
0.000 0.362 0.638
E41 Nutritional marasmus
0.000 0.362 0.638
E40 Kwashiorkor
0.000 0.362 0.638
M65.2 Calcific tendinitis
0.000 0.362 0.638
M65.0 Abscess of tendon sheath
0.000 0.362 0.638
K77 Liver disorders in diseases classified elsewhere
0.000 0.362 0.638
K51 Ulcerative colitis
0.635 0.363 0.002
J45.9 Asthma, unspecified
0.000 0.363 0.637
H40 Glaucoma
0.000 0.367 0.633
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.368 0.632
H91.3 Deaf mutism, not elsewhere classified
0.000 0.369 0.631
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.369 0.631
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.000 0.370 0.630
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.000 0.370 0.630
C09 Malignant neoplasm of tonsil
0.000 0.373 0.627
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.373 0.627
M05.2 Rheumatoid vasculitis
0.000 0.373 0.626
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.374 0.626
C85.0 Lymphosarcoma
0.000 0.374 0.626
E06.9 Thyroiditis, unspecified
0.000 0.374 0.626
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)
0.000 0.375 0.625
M35.8 Other specified systemic involvement of connective tissue
0.000 0.375 0.624
K50.0 Crohn's disease of small intestine
0.000 0.376 0.624
L51 Erythema multiforme
0.000 0.376 0.624
C45.0 Mesothelioma of pleura
0.000 0.376 0.624
C12 Malignant neoplasm of pyriform sinus
0.000 0.376 0.624
M25.68 Stiffness of joint, not elsewhere classified (Other)
0.000 0.377 0.623
H40.9 Glaucoma, unspecified
0.000 0.378 0.622
K74.4 Secondary biliary cirrhosis
0.000 0.378 0.622
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.378 0.622
K74.1 Hepatic sclerosis
0.000 0.378 0.622
K51.3 Ulcerative (chronic) rectosigmoiditis
0.621 0.379 0.000
M14.6 Neuropathic arthropathy
0.000 0.382 0.618
J86.9 Pyothorax without fistula
0.000 0.383 0.617
H92 Otalgia and effusion of ear
0.000 0.383 0.617
M34.1 CR(E)ST syndrome
0.000 0.386 0.614
C84.0 Mycosis fungoides
0.000 0.387 0.612
M35.7 Hypermobility syndrome
0.000 0.388 0.612
M35.2 Behcet's disease
0.000 0.388 0.612
M60.0 Infective myositis
0.000 0.389 0.611
M00-M03 Infectious arthropathies
0.000 0.389 0.610
K75.4 Autoimmune hepatitis
0.000 0.390 0.610
L52 Erythema nodosum
0.000 0.390 0.610
J38.5 Laryngeal spasm
0.000 0.391 0.609
E13.8 With unspecified complications
0.000 0.392 0.608
E13.7 With multiple complications
0.000 0.392 0.608
E13.6 With other specified complications
0.000 0.392 0.608
E13.5 With peripheral circulatory complications
0.000 0.392 0.608
E13.4 With neurological complications
0.000 0.392 0.608
E13.3 With ophthalmic complications
0.000 0.392 0.608
E13.2 With renal complications
0.000 0.392 0.608
E13.1 With ketoacidosis
0.000 0.392 0.608
E13.0 With coma
0.000 0.392 0.608
M07.38 Other psoriatic arthropathies (Other)
0.000 0.392 0.608
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.392 0.608
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.392 0.608
M25.47 Effusion of joint (Ankle and foot)
0.000 0.393 0.607
H44.0 Purulent endophthalmitis
0.000 0.393 0.607
M65.1 Other infective (teno)synovitis
0.000 0.394 0.606
C45.7 Mesothelioma of other sites
0.000 0.395 0.605
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.000 0.395 0.605
E07.1 Dyshormogenetic goitre
0.000 0.395 0.605
E07.0 Hypersecretion of calcitonin
0.000 0.395 0.605
H61.2 Impacted cerumen
0.000 0.395 0.605
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec
0.000 0.396 0.603
M65.48 Radial styloid tenosynovitis [de Quervain]-Other
0.000 0.396 0.603
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot
0.000 0.396 0.603
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg
0.000 0.396 0.603
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh
0.000 0.396 0.603
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm
0.000 0.396 0.603
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region
0.000 0.396 0.603
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)
0.000 0.396 0.603
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)
0.000 0.397 0.603
H61.0 Perichondritis of external ear
0.000 0.399 0.601
C95.9 Leukaemia, unspecified
0.000 0.399 0.601
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.400 0.600
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.400 0.600
H60.9 Otitis externa, unspecified
0.000 0.401 0.599
C84.5 Other and unspecified T-cell lymphomas
0.000 0.403 0.597
J32.3 Chronic sphenoidal sinusitis
0.000 0.403 0.597
C83.7 Burkitt's tumour
0.000 0.403 0.597
K74.5 Biliary cirrhosis, unspecified
0.000 0.403 0.597
H95.1 Other disorders following mastoidectomy
0.000 0.404 0.596
J32.0 Chronic maxillary sinusitis
0.000 0.405 0.595
H30.9 Chorioretinal inflammation, unspecified
0.000 0.407 0.593
J39 Other diseases of upper respiratory tract
0.000 0.408 0.592
M33 Dermatopolymyositis
0.000 0.408 0.592
M31.1 Thrombotic microangiopathy
0.000 0.408 0.592
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.408 0.591
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.408 0.591
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.408 0.591
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.408 0.591
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.408 0.591
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.408 0.591
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.408 0.591
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.408 0.591
M25.63 Stiffness of joint, not elsewhere classified (Forearm)
0.000 0.409 0.591
J37.1 Chronic laryngotracheitis
0.000 0.410 0.590
K71 Toxic liver disease
0.000 0.411 0.589
J35 Chronic diseases of tonsils and adenoids
0.000 0.411 0.589
H60.8 Other otitis externa
0.000 0.413 0.587
J42 Unspecified chronic bronchitis
0.000 0.413 0.587
H91.8 Other specified hearing loss
0.000 0.413 0.587
C91.5 Adult T-cell leukaemia
0.000 0.413 0.587
M25.9 Joint disorder, unspecified
0.000 0.415 0.585
M25.06 Haemarthrosis (Lower leg)
0.000 0.416 0.584
C94 Other leukaemias of specified cell type
0.000 0.416 0.584
M34.8 Other forms of systemic sclerosis
0.000 0.416 0.584
H34.1 Central retinal artery occlusion
0.000 0.417 0.583
H40.5 Glaucoma secondary to other eye disorders
0.000 0.417 0.583
C11 Malignant neoplasm of nasopharynx
0.000 0.417 0.583
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)
0.000 0.419 0.581
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.000 0.420 0.580
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)
0.000 0.420 0.580

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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