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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3129932
log Bayes Factor = 217.142
Chromosome 6   position 32,336,127  (GRCh37) Explore rs3129932 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E14.9 Without complications
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E10.4 With neurological complications
0.000 0.000 1.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.000 1.000
J33 Nasal polyp
0.000 0.000 1.000
M35.3 Polymyalgia rheumatica
0.000 0.001 0.999
J33.0 Polyp of nasal cavity
0.000 0.001 0.999
E70-E90 Metabolic disorders
0.000 0.001 0.999
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.001 0.999
E05.9 Thyrotoxicosis, unspecified
0.000 0.001 0.999
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.001 0.999
J33.9 Nasal polyp, unspecified
0.000 0.001 0.999
L40-L45 Papulosquamous disorders
0.000 0.002 0.998
E11.3 With ophthalmic complications
0.000 0.002 0.998
M07 Psoriatic and enteropathic arthropathies
0.000 0.002 0.998
H36 Retinal disorders in diseases classified elsewhere
0.000 0.003 0.997
M07.3 Other psoriatic arthropathies
0.000 0.003 0.997
G35-G37 Demyelinating diseases of the central nervous system
0.997 0.003 0.000
E14.3 With ophthalmic complications
0.000 0.003 0.997
G37 Other demyelinating diseases of central nervous system
0.996 0.004 0.000
L40.9 Psoriasis, unspecified
0.000 0.004 0.996
G37.9 Demyelinating disease of central nervous system, unspecified
0.995 0.005 0.000
H30-H36 Disorders of choroid and retina
0.000 0.005 0.995
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.006 0.994
M35 Other systemic involvement of connective tissue
0.000 0.007 0.993
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.007 0.993
J33.8 Other polyp of sinus
0.000 0.008 0.992
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.008 0.992
E10.5 With peripheral circulatory complications
0.000 0.008 0.992
E11.1 With ketoacidosis
0.000 0.009 0.991
I10 Essential (primary) hypertension
0.000 0.012 0.988
I10-I15 Hypertensive diseases
0.000 0.013 0.987
# Top node
0.000 0.014 0.986
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.016 0.984
M20-M25 Other joint disorders
0.000 0.016 0.984
Chapter VII Diseases of the eye and adnexa
0.000 0.017 0.983
L43 Lichen planus
0.000 0.018 0.982
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.019 0.981
Chapter IX Diseases of the circulatory system
0.000 0.025 0.975
E10.2 With renal complications
0.000 0.027 0.973
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.030 0.970
E06 Thyroiditis
0.000 0.030 0.970
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.041 0.959
I22 Subsequent myocardial infarction
0.000 0.041 0.959
I12 Hypertensive renal disease
0.000 0.042 0.958
L43.9 Lichen planus, unspecified
0.000 0.042 0.958
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.043 0.957
I20-I25 Ischaemic heart diseases
0.000 0.043 0.957
E10.8 With unspecified complications
0.000 0.046 0.954
E06.3 Autoimmune thyroiditis
0.000 0.048 0.952
M06.0 Seronegative rheumatoid arthritis
0.000 0.049 0.951
I12.9 Hypertensive renal disease without renal failure
0.000 0.054 0.946
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.055 0.945
M65-M68 Disorders of synovium and tendon
0.000 0.057 0.943
H34 Retinal vascular occlusions
0.000 0.057 0.943
M34 Systemic sclerosis
0.000 0.058 0.942
E10.0 With coma
0.000 0.058 0.942
M06.3 Rheumatoid nodule
0.000 0.060 0.940
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.062 0.938
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.069 0.931
E78.2 Mixed hyperlipidaemia
0.000 0.071 0.929
H40-H42 Glaucoma
0.000 0.072 0.928
M65 Synovitis and tenosynovitis
0.000 0.072 0.928
M45-M49 Spondylopathies
0.000 0.083 0.917
M45 Ankylosing spondylitis
0.000 0.085 0.915
H35 Other retinal disorders
0.000 0.092 0.908
M06.4 Inflammatory polyarthropathy
0.000 0.092 0.908
M65.9 Synovitis and tenosynovitis, unspecified
0.000 0.093 0.907
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.097 0.903
E07 Other disorders of thyroid
0.000 0.100 0.900
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.102 0.898
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.102 0.898
E78.1 Pure hyperglyceridaemia
0.000 0.107 0.893
H40 Glaucoma
0.000 0.111 0.889
H40.9 Glaucoma, unspecified
0.000 0.115 0.885
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.118 0.882
E11.2 With renal complications
0.000 0.119 0.880
E88 Other metabolic disorders
0.000 0.122 0.878
E11.5 With peripheral circulatory complications
0.000 0.126 0.874
H35.4 Peripheral retinal degeneration
0.000 0.133 0.867
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.136 0.863
G37.8 Other specified demyelinating diseases of central nervous system
0.861 0.139 0.000
M34.1 CR(E)ST syndrome
0.000 0.141 0.859
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.142 0.858
H35.8 Other specified retinal disorders
0.000 0.144 0.856
L40.8 Other psoriasis
0.000 0.145 0.855
M35.7 Hypermobility syndrome
0.000 0.146 0.854
L43.8 Other lichen planus
0.000 0.146 0.854
M35.1 Other overlap syndromes
0.000 0.147 0.853
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.148 0.852
M34.9 Systemic sclerosis, unspecified
0.000 0.157 0.843
H34.8 Other retinal vascular occlusions
0.000 0.161 0.839
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.164 0.836
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.165 0.835
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.166 0.834
M06.34 Rheumatoid nodule (Hand)
0.000 0.167 0.833
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.000 0.168 0.832
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.172 0.828
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.174 0.826
E10.6 With other specified complications
0.000 0.183 0.817
D64.9 Anaemia, unspecified
0.000 0.185 0.815
E07.9 Disorder of thyroid, unspecified
0.000 0.188 0.812
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.190 0.810
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.190 0.810
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.192 0.808
H34.2 Other retinal artery occlusions
0.000 0.193 0.807
D64 Other anaemias
0.000 0.196 0.804
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.197 0.803
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.197 0.803
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.198 0.802
D60-D64 Aplastic and other anaemias
0.000 0.198 0.802
E11.8 With unspecified complications
0.000 0.202 0.798
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.000 0.202 0.798
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)
0.000 0.207 0.793
E14.4 With neurological complications
0.000 0.209 0.791
E03.8 Other specified hypothyroidism
0.000 0.211 0.789
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.000 0.211 0.789
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.217 0.783
I15 Secondary hypertension
0.000 0.217 0.783
H35.6 Retinal haemorrhage
0.000 0.218 0.782
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.222 0.778
M30 Polyarteritis nodosa and related conditions
0.000 0.225 0.775
E74 Other disorders of carbohydrate metabolism
0.000 0.226 0.774
H43-H45 Disorders of vitreous body and globe
0.000 0.227 0.773
E83 Disorders of mineral metabolism
0.354 0.233 0.413
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.234 0.766
E89.0 Postprocedural hypothyroidism
0.000 0.236 0.764
I22.8 Subsequent myocardial infarction of other sites
0.000 0.238 0.762
M35.2 Behcet's disease
0.000 0.239 0.761
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.244 0.756
E14.5 With peripheral circulatory complications
0.000 0.247 0.753
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.254 0.746
M31 Other necrotising vasculopathies
0.000 0.261 0.739
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.263 0.737
H35.7 Separation of retinal layers
0.000 0.264 0.736
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.000 0.265 0.734
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.733 0.267 0.000
L40.3 Pustulosis palmaris et plantaris
0.000 0.268 0.732
E14.2 Withrenal complications
0.000 0.268 0.731
G36 Other acute disseminated demyelination
0.729 0.270 0.000
H33 Retinal detachments and breaks
0.000 0.272 0.728
M65.1 Other infective (teno)synovitis
0.000 0.276 0.724
M14 Arthropathies in other diseases classified elsewhere
0.000 0.276 0.723
H34.9 Retinal vascular occlusion, unspecified
0.000 0.280 0.720
H34.1 Central retinal artery occlusion
0.000 0.282 0.718
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E14.8 With unspecified complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.6 With other specified complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.2 Rheumatoid vasculitis
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E78.6 Lipoprotein deficiency
0.000 0.283 0.717
E78.3 Hyperchylomicronaemia
0.000 0.283 0.717
J33.1 Polypoid sinus degeneration
0.000 0.283 0.717
E77 Disorders of glycoprotein metabolism
0.000 0.284 0.716
E76 Disorders of glycosaminoglycan metabolism
0.000 0.284 0.716
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.284 0.716
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.284 0.716
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.284 0.716
L44 Other papulosquamous disorders
0.000 0.284 0.716
L41 Parapsoriasis
0.000 0.284 0.716
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.284 0.716
M07.5 Arthropathy in ulcerative colitis
0.000 0.284 0.715
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.284 0.715
M07.2 Psoriatic spondylitis
0.000 0.284 0.715
M07.1 Arthritis mutilans
0.000 0.284 0.715
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.284 0.715
H40.4 Glaucoma secondary to eye inflammation
0.000 0.285 0.715
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.285 0.715
M07.38 Other psoriatic arthropathies (Other)
0.000 0.285 0.715
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.285 0.715
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.285 0.715
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.285 0.715
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.285 0.715
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.285 0.715
G37.5 Concentric sclerosis [Balo]
0.714 0.286 0.000
G37.4 Subacute necrotising myelitis
0.714 0.286 0.000
G37.2 Central pontine myelinolysis
0.714 0.286 0.000
G37.1 Central demyelination of corpus callosum
0.714 0.286 0.000
G37.0 Diffuse sclerosis
0.714 0.286 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.286 0.713
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.288 0.712
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.288 0.712
M35.5 Multifocal fibrosclerosis
0.000 0.288 0.712
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.288 0.712
L40.0 Psoriasis vulgaris
0.000 0.291 0.709
I00-I02 Acute rheumatic fever
0.000 0.292 0.708
H30 Chorioretinal inflammation
0.000 0.292 0.708
I13 Hypertensive heart and renal disease
0.000 0.292 0.708
H43 Disorders of vitreous body
0.000 0.292 0.708
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.293 0.707
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.293 0.707
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.294 0.706
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.294 0.706
L43.3 Subacute (active) lichen planus
0.000 0.296 0.704
L43.2 Lichenoid drug reaction
0.000 0.296 0.704
L43.1 Bullous lichen planus
0.000 0.296 0.704
L43.0 Hypertrophic lichen planus
0.000 0.296 0.704
E70 Disorders of aromatic amino-acid metabolism
0.000 0.299 0.701
E88.2 Lipomatosis, not elsewhere classified
0.000 0.300 0.700
E88.8 Other specified metabolic disorders
0.000 0.301 0.699
E13 Other specified diabetes mellitus
0.000 0.301 0.699
I11 Hypertensive heart disease
0.000 0.302 0.698
E11.6 With other specified complications
0.000 0.303 0.697
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.304 0.696
E06.5 Other chronic thyroiditis
0.000 0.304 0.696
E06.4 Drug-induced thyroiditis
0.000 0.304 0.696
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.304 0.696
E06.1 Subacute thyroiditis
0.000 0.304 0.696
E06.0 Acute thyroiditis
0.000 0.304 0.696
E40-E46 Malnutrition
0.000 0.305 0.695
E07.8 Other specified disorders of thyroid
0.000 0.306 0.693
E79 Disorders of purine and pyrimidine metabolism
0.000 0.308 0.692
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)
0.000 0.308 0.692
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.311 0.689
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.313 0.687
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.318 0.682
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.318 0.682
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.318 0.682
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.318 0.682
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.318 0.682
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.318 0.682
E16.1 Other hypoglycaemia
0.000 0.318 0.682
H40.5 Glaucoma secondary to other eye disorders
0.000 0.320 0.680
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.321 0.679
M34.8 Other forms of systemic sclerosis
0.000 0.321 0.679
E78.4 Other hyperlipidaemia
0.000 0.322 0.678
M12 Other specific arthropathies
0.000 0.323 0.676
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.324 0.676
H34.0 Transient retinal artery occlusion
0.000 0.324 0.676
M34.2 Systemic sclerosis induced by drugs and chemicals
0.000 0.325 0.675
M34.0 Progressive systemic sclerosis
0.000 0.325 0.675
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.326 0.674
M06.38 Rheumatoid nodule (Other)
0.000 0.326 0.674
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.326 0.674
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.326 0.674
M06.33 Rheumatoid nodule (Forearm)
0.000 0.326 0.674
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.326 0.674
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.326 0.674
M91-M94 Chondropathies
0.000 0.328 0.672
M86-M90 Other osteopathies
0.000 0.331 0.669
M07.6 Other enteropathic arthropathies
0.000 0.331 0.668
E84 Cystic fibrosis
0.000 0.333 0.666
H35.2 Other proliferative retinopathy
0.000 0.334 0.666
H42 Glaucoma in diseases classified elsewhere
0.000 0.334 0.666
M65.2 Calcific tendinitis
0.000 0.335 0.665
M65.0 Abscess of tendon sheath
0.000 0.335 0.665
M49 Spondylopathies in diseases classified elsewhere
0.000 0.335 0.665
E72 Other disorders of amino-acid metabolism
0.000 0.340 0.659
H33.3 Retinal breaks without detachment
0.000 0.340 0.660
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.344 0.656
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.344 0.656
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.344 0.656
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.344 0.656
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.344 0.656
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.344 0.656
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.344 0.656
H35.1 Retinopathy of prematurity
0.000 0.349 0.651
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.349 0.651
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.349 0.651
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.349 0.651
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.349 0.651
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.349 0.651
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.349 0.651
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.349 0.651
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.349 0.651
M65.98 Synovitis and tenosynovitis, unspecified (Other)
0.000 0.350 0.650
E06.9 Thyroiditis, unspecified
0.000 0.351 0.649
L10-L14 Bullous disorders
0.000 0.353 0.647
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)
0.000 0.353 0.647
E07.1 Dyshormogenetic goitre
0.000 0.355 0.645
E07.0 Hypersecretion of calcitonin
0.000 0.355 0.645
L57.0 Actinic keratosis
0.000 0.357 0.643
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.358 0.642
M32 Systemic lupus erythematosus
0.000 0.358 0.642
H40.6 Glaucoma secondary to drugs
0.000 0.362 0.638
H40.3 Glaucoma secondary to eye trauma
0.000 0.362 0.638
M66 Spontaneous rupture of synovium and tendon
0.000 0.364 0.636
E88.3 Tumour lysis syndrome
0.000 0.367 0.633
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec
0.000 0.368 0.632
M65.48 Radial styloid tenosynovitis [de Quervain]-Other
0.000 0.368 0.632
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot
0.000 0.368 0.632
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg
0.000 0.368 0.632
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh
0.000 0.368 0.632
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm
0.000 0.368 0.632
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region
0.000 0.368 0.632
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)
0.000 0.368 0.632
E11.4 With neurological complications
0.000 0.369 0.631
H43.3 Other vitreous opacities
0.000 0.371 0.629
E88.9 Metabolic disorder, unspecified
0.000 0.371 0.629
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.371 0.629
M11 Other crystal arthropathies
0.000 0.375 0.624
D62 Acute posthaemorrhagic anaemia
0.000 0.378 0.622
E89.4 Postprocedural ovarian failure
0.000 0.380 0.620
L42 Pityriasis rosea
0.000 0.383 0.616
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.384 0.616
M31.6 Other giant cell arteritis
0.000 0.384 0.616
Chapter VIII Diseases of the ear and mastoid process
0.000 0.386 0.614
I15.9 Seconday hypertension, unspecified
0.000 0.386 0.614
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.387 0.613
M86 Osteomyelitis
0.000 0.389 0.611
E05.8 Other thyrotoxicosis
0.000 0.390 0.610
M15-M19 Arthrosis
0.000 0.391 0.609
E73 Lactose intolerance
0.000 0.393 0.607
H40.1 Primary open-angle glaucoma
0.000 0.396 0.604
H43.9 Disorder of vitreous body, unspecified
0.000 0.396 0.604
I15.1 Hypertension secondary to other renal disorders
0.000 0.399 0.601
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.000 0.401 0.598
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.406 0.594
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.408 0.592
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.408 0.592
E89.5 Postprocedural testicular hypofunction
0.000 0.408 0.592
E89.1 Postprocedural hypoinsulinaemia
0.000 0.408 0.592
E65-E68 Obesity and other hyperalimentation
0.000 0.409 0.591
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.409 0.591
I21 Acute myocardial infarction
0.000 0.409 0.591
M33 Dermatopolymyositis
0.000 0.409 0.591
M30.0 Polyarteritis nodosa
0.000 0.410 0.590
M60-M63 Disorders of muscles
0.000 0.410 0.589
M80-M85 Disorders of bone density and structure
0.000 0.410 0.590
I23 Certain current complications following acute myocardial infarction
0.000 0.413 0.587
M35.0 Sicca syndrome [Sjogren]
0.000 0.416 0.584
M14.6 Neuropathic arthropathy
0.000 0.416 0.584
H33.4 Traction detachment of retina
0.000 0.417 0.583
H60-H62 Diseases of external ear
0.000 0.418 0.582
M65.14 Other infective (teno)synovitis (Hand)
0.000 0.422 0.578
M86.9 Osteomyelitis, unspecified
0.000 0.422 0.578
D64.4 Congenital dyserythropoietic anaemia
0.000 0.423 0.577
D64.3 Other sideroblastic anaemias
0.000 0.423 0.577
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.423 0.577
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.423 0.577
D64.0 Hereditary sideroblastic anaemia
0.000 0.423 0.577
M10 Gout
0.000 0.424 0.576
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.425 0.575
H40.0 Glaucoma suspect
0.000 0.426 0.573
E11.0 With coma
0.000 0.431 0.569
E89.3 Postprocedural hypopituitarism
0.000 0.436 0.563
E78.8 Other disorders of lipoprotein metabolism
0.000 0.437 0.563
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.000 0.437 0.563
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.437 0.563
E20-E35 Disorders of other endocrine glands
0.000 0.438 0.562
E03.1 Congenital hypothyroidism without goitre
0.000 0.438 0.562
I15.8 Other secondary hypertension
0.000 0.439 0.561
I15.2 Hypertension secondary to endocrine disorders
0.000 0.439 0.561
M00-M03 Infectious arthropathies
0.000 0.440 0.560
L55 Sunburn
0.000 0.442 0.558
M18 Arthrosis of first carpometacarpal joint
0.000 0.443 0.557
M30.8 Other conditions related to polyarteritis nodosa
0.000 0.444 0.556
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]
0.000 0.444 0.556
M30.2 Juvenile polyarteritis
0.000 0.444 0.556
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.445 0.555
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.445 0.555
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.445 0.555
E74.2 Disorders of galactose metabolism
0.000 0.445 0.555
E74.1 Disorders of fructose metabolism
0.000 0.445 0.555
E74.0 Glycogen storage disease
0.000 0.445 0.555
M31.3 Wegener's granulomatosis
0.000 0.446 0.554
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.446 0.554
E83.8 Other disorders of mineral metabolism
0.254 0.450 0.296
E83.2 Disorders of zinc metabolism
0.254 0.450 0.296
E83.0 Disorders of copper metabolism
0.254 0.450 0.296
I15.0 Renovascular hypertension
0.000 0.452 0.548
D55-D59 Haemolytic anaemias
0.000 0.460 0.540
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.460 0.540
M31.9 Necrotising vasculopathy, unspecified
0.000 0.460 0.540
G36.0 Neuromyelitis optica [Devic]
0.538 0.462 0.000
D50-D53 Nutritional anaemias
0.000 0.463 0.537
M31.1 Thrombotic microangiopathy
0.000 0.463 0.537
E83.9 Disorder of mineral metabolism, unspecified
0.275 0.463 0.262
H61 Other disorders of external ear
0.000 0.463 0.537
M18.1 Other primary arthrosis of first carpometacarpal joint
0.000 0.465 0.535
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.000 0.465 0.535
H43.2 Crystalline deposits in vitreous body
0.000 0.466 0.534
E89.2 Postprocedural hypoparathyroidism
0.000 0.467 0.533
L20-L30 Dermatitis and eczema
0.000 0.469 0.531
I21.9 Acute myocardial infarction, unspecified
0.000 0.469 0.531
M31.8 Other specified necrotising vasculopathies
0.000 0.470 0.530
M31.7 Microscopic polyangiitis
0.000 0.470 0.530
M31.4 Aortic arch syndrome [Takayasu]
0.000 0.470 0.530
M31.2 Lethal midline granuloma
0.000 0.470 0.530
H33.1 Retinoschisis and retinal cysts
0.000 0.470 0.530
M82 Osteoporosis in diseases classified elsewhere
0.000 0.472 0.528
H35.5 Hereditary retinal dystrophy
0.000 0.473 0.527
G36.9 Acute disseminated demyelination, unspecified
0.523 0.477 0.000
G36.8 Other specified acute disseminated demyelination
0.523 0.477 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.523 0.477 0.000
M65.19 Other infective (teno)synovitis (Site unspecified)
0.000 0.481 0.519
M65.18 Other infective (teno)synovitis (Other)
0.000 0.481 0.519
M65.17 Other infective (teno)synovitis (Ankle and foot)
0.000 0.481 0.519
M65.16 Other infective (teno)synovitis (Lower leg)
0.000 0.481 0.519
M65.15 Other infective (teno)synovitis (Pelvic region and thigh)
0.000 0.481 0.519
M65.13 Other infective (teno)synovitis (Forearm)
0.000 0.481 0.519
M65.12 Other infective (teno)synovitis (Upper arm)
0.000 0.481 0.519
M65.11 Other infective (teno)synovitis (Shoulder region)
0.000 0.481 0.519
M65.10 Other infective (teno)synovitis (Multiple sites)
0.000 0.481 0.519
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.481 0.519
M14.4 Arthropathy in amyloidosis
0.000 0.481 0.519
M14.3 Lipoid dermatoarthritis
0.000 0.481 0.519
M14.2 Diabetic arthropathy
0.000 0.481 0.519
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.481 0.519
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.481 0.519
I00 Rheumatic fever without mention of heart involvement
0.000 0.482 0.517
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.484 0.516
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.484 0.515
I24 Other acute ischaemic heart diseases
0.000 0.485 0.515
M80 Osteoporosis with pathological fracture
0.000 0.486 0.514
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.486 0.514
M06.18 Adult-onset Still's disease (Other)
0.000 0.486 0.514
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.486 0.514
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.486 0.514
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.486 0.514
M06.14 Adult-onset Still's disease (Hand)
0.000 0.486 0.514
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.486 0.514
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.486 0.514
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.486 0.514
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.486 0.514
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.486 0.514
M06.28 Rheumatoid bursitis (Other)
0.000 0.486 0.514
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.486 0.514
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.486 0.514
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.486 0.514
M06.24 Rheumatoid bursitis (Hand)
0.000 0.486 0.514
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.486 0.514
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.486 0.514
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.486 0.514
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.486 0.514
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.486 0.514
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.486 0.514
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.486 0.514
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.486 0.514
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.486 0.514
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.486 0.514
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.486 0.514
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.486 0.514
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.486 0.514

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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