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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9501589
log Bayes Factor = 107.041
Chromosome 6   position 31,364,383  (GRCh37) Explore rs9501589 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
M07.3 Other psoriatic arthropathies
1.000 0.000 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
L40 Psoriasis
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
M07.39 Other psoriatic arthropathies (Site unspecified)
1.000 0.000 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
1.000 0.000 0.000
E03 Other hypothyroidism
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
L40.0 Psoriasis vulgaris
0.999 0.001 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.002 0.998
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.003 0.997
M45 Ankylosing spondylitis
0.997 0.003 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.004 0.996
E10.3 With ophthalmic complications
0.000 0.004 0.996
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.996 0.004 0.000
E27 Other disorders of adrenal gland
0.000 0.004 0.996
E20-E35 Disorders of other endocrine glands
0.000 0.005 0.995
E16 Other disorders of pancreatic internal secretion
0.000 0.005 0.995
E16.2 Hypoglycaemia, unspecified
0.000 0.008 0.992
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.011 0.989
E10.1 With ketoacidosis
0.000 0.023 0.977
E05.9 Thyrotoxicosis, unspecified
0.000 0.037 0.963
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.948 0.052 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.078 0.922
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.918 0.082 0.000
E10.0 With coma
0.000 0.084 0.916
E10.4 With neurological complications
0.000 0.085 0.915
G35 Multiple sclerosis
0.000 0.085 0.915
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.096 0.904
M07.34 Other psoriatic arthropathies (Hand)
0.876 0.124 0.000
L40.4 Guttate psoriasis
0.872 0.128 0.000
E20 Hypoparathyroidism
0.000 0.128 0.872
E10.2 With renal complications
0.000 0.133 0.867
L40.1 Generalised pustular psoriasis
0.867 0.133 0.000
E27.2 Addisonian crisis
0.000 0.142 0.858
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.855 0.145 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.852 0.148 0.000
M07.38 Other psoriatic arthropathies (Other)
0.829 0.171 0.000
E14 Unspecified diabetes mellitus
0.000 0.181 0.819
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.182 0.818
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.808 0.192 0.000
L40.8 Other psoriasis
0.786 0.214 0.000
E20.9 Hypoparathyroidism, unspecified
0.000 0.216 0.784
C82.0 Small cleaved cell, follicular
0.773 0.227 0.000
E10.6 With other specified complications
0.000 0.230 0.770
M45.X6 Ankylosing spondylitis (Lumbar region)
0.770 0.230 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.762 0.238 0.000
D69.6 Thrombocytopenia, unspecified
0.000 0.263 0.737
D69 Purpura and other haemorrhagic conditions
0.000 0.274 0.726
M45.X2 Ankylosing spondylitis (Cervical region)
0.721 0.279 0.000
K90 Intestinal malabsorption
0.000 0.279 0.721
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.282 0.718
M07.33 Other psoriatic arthropathies (Forearm)
0.717 0.283 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.717 0.283 0.000
E10.7 With multiple complications
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.716 0.283 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.284 0.716
E05.5 Thyroid crisis or storm
0.000 0.285 0.715
E05.4 Thyrotoxicosis factitia
0.000 0.285 0.715
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.285 0.715
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.285 0.715
E26 Hyperaldosteronism
0.000 0.285 0.715
E15 Nondiabetic hypoglycaemic coma
0.000 0.285 0.715
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.715 0.285 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.715 0.285 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.715 0.285 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.715 0.285 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.715 0.285 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.715 0.285 0.000
E27.5 Adrenomedullary hyperfunction
0.000 0.286 0.714
E27.0 Other adrenocortical overactivity
0.000 0.286 0.714
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.287 0.713
E32 Diseases of thymus
0.000 0.287 0.713
E31 Polyglandular dysfunction
0.000 0.287 0.713
E30 Disorders of puberty, not elsewhere classified
0.000 0.287 0.713
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.287 0.713
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.287 0.713
E16.4 Abnormal secretion of gastrin
0.000 0.287 0.713
E16.3 Increased secretion of glucagon
0.000 0.287 0.713
E07 Other disorders of thyroid
0.000 0.298 0.702
E10.5 With peripheral circulatory complications
0.000 0.299 0.701
C82.4 Follicular lymphoma grade IIIb
0.696 0.304 0.000
E14.9 Without complications
0.000 0.304 0.696
E10.8 With unspecified complications
0.000 0.305 0.695
E06 Thyroiditis
0.000 0.311 0.689
E23 Hypofunction and other disorders of pituitary gland
0.000 0.315 0.685
C82.1 Mixed small cleaved and large cell, follicular
0.685 0.315 0.000
C82.3 Follicular lymphoma grade IIIa
0.682 0.318 0.000
E22 Hyperfunction of pituitary gland
0.000 0.323 0.677
E25 Adrenogenital disorders
0.000 0.327 0.672
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.330 0.670
E03.8 Other specified hypothyroidism
0.000 0.334 0.666
E40-E46 Malnutrition
0.000 0.335 0.665
L40.3 Pustulosis palmaris et plantaris
0.660 0.340 0.000
E27.8 Other specified disorders of adrenal gland
0.000 0.344 0.656
C82.2 Large cell, follicular
0.655 0.345 0.000
E14.6 With other specified complications
0.000 0.346 0.654
L40-L45 Papulosquamous disorders
0.653 0.347 0.000
E05.8 Other thyrotoxicosis
0.000 0.348 0.652
K90.9 Intestinal malabsorption, unspecified
0.000 0.351 0.649
D69.5 Secondary thrombocytopenia
0.000 0.351 0.649
E14.1 With ketoacidosis
0.000 0.361 0.639
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.368 0.632
E20.8 Other hypoparathyroidism
0.000 0.375 0.625
E20.1 Pseudohypoparathyroidism
0.000 0.375 0.625
E20.0 Idiopathic hypoparathyroidism
0.000 0.375 0.625
E28 Ovarian dysfunction
0.000 0.377 0.623
E07.8 Other specified disorders of thyroid
0.000 0.382 0.618
C82.6 Cutaneous follicle centre lymphoma
0.613 0.387 0.000
C82.5 Diffuse follicle centre lymphoma
0.613 0.387 0.000
E06.3 Autoimmune thyroiditis
0.000 0.402 0.598
E14.2 Withrenal complications
0.000 0.402 0.598
E34 Other endocrine disorders
0.000 0.408 0.592
K90.8 Other intestinal malabsorption
0.000 0.410 0.590
E23.2 Diabetes insipidus
0.000 0.411 0.589
E14.7 With multiple complications
0.000 0.413 0.587
E14.0 With coma
0.000 0.413 0.587
D69.4 Other primary thrombocytopenia
0.000 0.420 0.580
D69.2 Other nonthrombocytopenic purpura
0.000 0.423 0.577
L42 Pityriasis rosea
0.577 0.423 0.000
E14.5 With peripheral circulatory complications
0.000 0.426 0.574
D69.0 Allergic purpura
0.000 0.437 0.563
E16.1 Other hypoglycaemia
0.000 0.445 0.555
E13 Other specified diabetes mellitus
0.000 0.448 0.551
E14.8 With unspecified complications
0.000 0.449 0.551
E23.7 Disorder of pituitary gland, unspecified
0.000 0.451 0.549
M35.0 Sicca syndrome [Sjogren]
0.000 0.456 0.544
M35.3 Polymyalgia rheumatica
0.000 0.463 0.537
M35 Other systemic involvement of connective tissue
0.000 0.463 0.537
E22.0 Acromegaly and pituitary gigantism
0.000 0.468 0.532
E14.3 With ophthalmic complications
0.000 0.475 0.525
E29 Testicular dysfunction
0.000 0.477 0.523
D69.8 Other specified haemorrhagic conditions
0.000 0.479 0.520
E26.0 Primary hyperaldosteronism
0.000 0.480 0.520
E14.4 With neurological complications
0.000 0.482 0.518
K90.3 Pancreatic steatorrhoea
0.000 0.483 0.517
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.483 0.517
K90.1 Tropical sprue
0.000 0.483 0.517
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E26.8 Other hyperaldosteronism
0.000 0.487 0.512
E26.1 Secondary hyperaldosteronism
0.000 0.487 0.512
E30.9 Disorder of puberty, unspecified
0.000 0.488 0.511
E30.8 Other disorders of puberty
0.000 0.488 0.511
E30.1 Precocious puberty
0.000 0.488 0.511
E30.0 Delayed puberty
0.000 0.488 0.511
E31.9 Polyglandular dysfunction, unspecified
0.000 0.488 0.511
E31.8 Other polyglandular dysfunction
0.000 0.488 0.511
E31.1 Polyglandular hyperfunction
0.000 0.488 0.511
E31.0 Autoimmune polyglandular failure
0.000 0.488 0.511
E32.9 Disease of thymus, unspecified
0.000 0.488 0.511
E32.8 Other diseases of thymus
0.000 0.488 0.511
E32.1 Abscess of thymus
0.000 0.488 0.511
E32.0 Persistent hyperplasia of thymus
0.000 0.488 0.511
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.488 0.511
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.488 0.511
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.488 0.511
L41 Parapsoriasis
0.510 0.490 0.000
D69.1 Qualitative platelet defects
0.000 0.492 0.508
E26.9 Hyperaldosteronism, unspecified
0.000 0.493 0.506
E27.3 Drug-induced adrenocortical insufficiency
0.001 0.495 0.505
E28.3 Primary ovarian failure
0.000 0.496 0.504
E07.1 Dyshormogenetic goitre
0.000 0.497 0.503
E07.0 Hypersecretion of calcitonin
0.000 0.497 0.503
E06.4 Drug-induced thyroiditis
0.000 0.506 0.494
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.506 0.494
E06.0 Acute thyroiditis
0.000 0.506 0.494
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.509 0.491
E23.1 Drug-induced hypopituitarism
0.000 0.509 0.491
L44 Other papulosquamous disorders
0.486 0.514 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.514 0.486
E22.8 Other hyperfunction of pituitary gland
0.000 0.514 0.486
E25.9 Adrenogenital disorder, unspecified
0.000 0.518 0.482
E25.8 Other adrenogenital disorders
0.000 0.518 0.482
E06.5 Other chronic thyroiditis
0.000 0.521 0.478
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.523 0.477
E45 Retarded development following protein-energy malnutrition
0.000 0.523 0.477
E43 Unspecified severe protein-energy malnutrition
0.000 0.523 0.477
E42 Marasmic kwashiorkor
0.000 0.523 0.477
E41 Nutritional marasmus
0.000 0.523 0.477
E40 Kwashiorkor
0.000 0.523 0.477
M35.1 Other overlap syndromes
0.000 0.528 0.472
L45 Papulosquamous disorders in diseases classified elsewhere
0.468 0.532 0.000
E22.1 Hyperprolactinaemia
0.000 0.534 0.465
E65-E68 Obesity and other hyperalimentation
0.000 0.535 0.465
E34.9 Endocrine disorder, unspecified
0.000 0.548 0.452
M07 Psoriatic and enteropathic arthropathies
0.451 0.549 0.000
E27.9 Disorder of adrenal gland, unspecified
0.001 0.550 0.450
E28.9 Ovarian dysfunction, unspecified
0.000 0.553 0.447
E28.8 Other ovarian dysfunction
0.000 0.553 0.447
E28.1 Androgen excess
0.000 0.553 0.447
E28.0 Oestrogen excess
0.000 0.553 0.447
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.554 0.446
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.556 0.444
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.558 0.441
E50-E64 Other nutritional deficiencies
0.000 0.570 0.430
E23.6 Other disorders of pituitary gland
0.000 0.571 0.429
E06.1 Subacute thyroiditis
0.000 0.573 0.426
E34.8 Other specified endocrine disorders
0.000 0.574 0.426
E34.5 Androgen resistance syndrome
0.000 0.576 0.424
E34.4 Constitutional tall stature
0.000 0.576 0.424
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.576 0.424
E34.1 Other hypersecretion of intestinal hormones
0.000 0.576 0.424
E46 Unspecified protein-energy malnutrition
0.000 0.576 0.424
L43 Lichen planus
0.411 0.588 0.000
M35.8 Other specified systemic involvement of connective tissue
0.000 0.589 0.411
L41.1 Pityriasis lichenoides chronica
0.407 0.593 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.595 0.404
D69.9 Haemorrhagic condition, unspecified
0.000 0.601 0.399
E13.8 With unspecified complications
0.000 0.604 0.395
E13.7 With multiple complications
0.000 0.604 0.395
E13.6 With other specified complications
0.000 0.604 0.395
E13.5 With peripheral circulatory complications
0.000 0.604 0.395
E13.4 With neurological complications
0.000 0.604 0.395
E13.3 With ophthalmic complications
0.000 0.604 0.395
E13.2 With renal complications
0.000 0.604 0.395
E13.1 With ketoacidosis
0.000 0.604 0.395
E13.0 With coma
0.000 0.604 0.395
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.615 0.385
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.615 0.385
M35.5 Multifocal fibrosclerosis
0.000 0.615 0.385
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.615 0.385
E29.9 Testicular dysfunction, unspecified
0.000 0.625 0.375
E29.8 Other testicular dysfunction
0.000 0.625 0.375
E29.0 Testicular hyperfunction
0.000 0.625 0.375
M35.2 Behcet's disease
0.000 0.626 0.374
L44.0 Pityriasis rubra pilaris
0.366 0.634 0.000
E34.3 Short stature, not elsewhere classified
0.000 0.634 0.365
L41.9 Parapsoriasis, unspecified
0.365 0.634 0.000
L41.8 Other parapsoriasis
0.365 0.634 0.000
L41.5 Retiform parapsoriasis
0.365 0.634 0.000
L41.4 Large plaque parapsoriasis
0.365 0.634 0.000
L41.3 Small plaque parapsoriasis
0.365 0.634 0.000
L41.2 Lymphomatoid papulosis
0.365 0.634 0.000
L41.0 Pityriasis lichenoides et varioliformis acuta
0.365 0.634 0.000
G37 Other demyelinating diseases of central nervous system
0.000 0.640 0.360
E06.9 Thyroiditis, unspecified
0.000 0.641 0.359
L44.9 Papulosquamous disorder, unspecified
0.348 0.651 0.000
L44.8 Other specified papulosquamous disorders
0.348 0.651 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.348 0.651 0.000
L44.3 Lichen ruber moniliformis
0.348 0.651 0.000
L44.2 Lichen striatus
0.348 0.651 0.000
L44.1 Lichen nitidus
0.348 0.651 0.000
M35.7 Hypermobility syndrome
0.000 0.653 0.347
E44.1 Mild protein-energy malnutrition
0.000 0.658 0.342
E44.0 Moderate protein-energy malnutrition
0.000 0.658 0.342
E65 Localised adiposity
0.000 0.661 0.339
E67 Other hyperalimentation
0.000 0.667 0.333
E68 Sequelae of hyperalimentation
0.000 0.667 0.333
E34.0 Carcinoid syndrome
0.000 0.667 0.333
E51 Thiamine deficiency
0.000 0.668 0.331
E53 Deficiency of other B group vitamins
0.000 0.670 0.330
E24 Cushing's syndrome
0.002 0.671 0.326
M07.6 Other enteropathic arthropathies
0.323 0.677 0.000
M07.5 Arthropathy in ulcerative colitis
0.323 0.677 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.323 0.677 0.000
M07.2 Psoriatic spondylitis
0.323 0.677 0.000
M07.1 Arthritis mutilans
0.323 0.677 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.323 0.677 0.000
E56 Other vitamin deficiencies
0.000 0.689 0.311
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.691 0.308
E63 Other nutritional deficiencies
0.000 0.691 0.308
E50 Vitamin A deficiency
0.000 0.691 0.308
E60 Dietary zinc deficiency
0.000 0.691 0.308
E59 Dietary selenium deficiency
0.000 0.691 0.308
E54 Ascorbic acid deficiency
0.000 0.691 0.308
E52 Niacin deficiency [pellagra]
0.000 0.691 0.308
G36 Other acute disseminated demyelination
0.000 0.695 0.305
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.702 0.297
L43.3 Subacute (active) lichen planus
0.295 0.705 0.000
L43.2 Lichenoid drug reaction
0.295 0.705 0.000
L43.1 Bullous lichen planus
0.295 0.705 0.000
L43.0 Hypertrophic lichen planus
0.295 0.705 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.716 0.284
E58 Dietary calcium deficiency
0.001 0.723 0.277
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.724 0.276
L43.8 Other lichen planus
0.271 0.729 0.000
L43.9 Lichen planus, unspecified
0.268 0.732 0.000
E51.2 Wernicke's encephalopathy
0.000 0.739 0.261
E04 Other non-toxic goitre
0.000 0.741 0.259
G37.5 Concentric sclerosis [Balo]
0.000 0.742 0.258
G37.4 Subacute necrotising myelitis
0.000 0.742 0.258
G37.2 Central pontine myelinolysis
0.000 0.742 0.258
G37.1 Central demyelination of corpus callosum
0.000 0.742 0.258
G37.0 Diffuse sclerosis
0.000 0.742 0.258
E53.9 Vitamin B deficiency, unspecified
0.000 0.751 0.249
E53.8 Deficiency of other specified B group vitamins
0.000 0.754 0.246
E67.8 Other specified hyperalimentation
0.000 0.761 0.239
E67.3 Hypervitaminosis D
0.000 0.761 0.239
E67.2 Megavitamin-B6 syndrome
0.000 0.761 0.239
E67.1 Hypercarotenaemia
0.000 0.761 0.239
E67.0 Hypervitaminosis A
0.000 0.761 0.239
E51.9 Thiamine deficiency, unspecified
0.000 0.762 0.238
E51.8 Other manifestations of thiamine deficiency
0.000 0.762 0.238
E51.1 Beriberi
0.000 0.762 0.238
E53.1 Pyridoxine deficiency
0.000 0.763 0.236
E53.0 Riboflavin deficiency
0.000 0.763 0.236
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.002 0.764 0.234
E24.3 Ectopic ACTH syndrome
0.002 0.764 0.234
E24.1 Nelson's syndrome
0.002 0.764 0.234
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.232 0.768 0.000
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.232 0.768 0.000
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.232 0.768 0.000
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.232 0.768 0.000
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.232 0.768 0.000
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.232 0.768 0.000
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.232 0.768 0.000
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.232 0.768 0.000
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.232 0.768 0.000
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.232 0.768 0.000
M07.19 Arthritis mutilans (Site unspecified)
0.232 0.768 0.000
M07.18 Arthritis mutilans (Other)
0.232 0.768 0.000
M07.17 Arthritis mutilans (Ankle and foot)
0.232 0.768 0.000
M07.16 Arthritis mutilans (Lower leg)
0.232 0.768 0.000
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.232 0.768 0.000
M07.14 Arthritis mutilans (Hand)
0.232 0.768 0.000
M07.13 Arthritis mutilans (Forearm)
0.232 0.768 0.000
M07.12 Arthritis mutilans (Upper arm)
0.232 0.768 0.000
M07.11 Arthritis mutilans (Shoulder region)
0.232 0.768 0.000
M07.10 Arthritis mutilans (Multiple sites)
0.232 0.768 0.000
M07.29 Psoriatic spondylitis (Site unspecified)
0.232 0.768 0.000
M07.28 Psoriatic spondylitis (Other)
0.232 0.768 0.000
M07.27 Psoriatic spondylitis (Ankle and foot)
0.232 0.768 0.000
M07.26 Psoriatic spondylitis (Lower leg)
0.232 0.768 0.000
M07.25 Psoriatic spondylitis (Pelvic region and thigh)
0.232 0.768 0.000
M07.24 Psoriatic spondylitis (Hand)
0.232 0.768 0.000
M07.23 Psoriatic spondylitis (Forearm)
0.232 0.768 0.000
M07.22 Psoriatic spondylitis (Upper arm)
0.232 0.768 0.000
M07.21 Psoriatic spondylitis (Shoulder region)
0.232 0.768 0.000
M07.20 Psoriatic spondylitis (Multiple sites)
0.232 0.768 0.000
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)
0.232 0.768 0.000
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)
0.232 0.768 0.000
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)
0.232 0.768 0.000
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)
0.232 0.768 0.000
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)
0.232 0.768 0.000
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)
0.232 0.768 0.000
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)
0.232 0.768 0.000
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)
0.232 0.768 0.000
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)
0.232 0.768 0.000
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)
0.232 0.768 0.000
M07.59 Arthropathy in ulcerative colitis (Site unspecified)
0.232 0.768 0.000
M07.58 Arthropathy in ulcerative colitis (Other)
0.232 0.768 0.000
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)
0.232 0.768 0.000
M07.56 Arthropathy in ulcerative colitis (Lower leg)
0.232 0.768 0.000
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)
0.232 0.768 0.000
M07.54 Arthropathy in ulcerative colitis (Hand)
0.232 0.768 0.000
M07.53 Arthropathy in ulcerative colitis (Forearm)
0.232 0.768 0.000
M07.52 Arthropathy in ulcerative colitis (Upper arm)
0.232 0.768 0.000
M07.51 Arthropathy in ulcerative colitis (Shoulder region)
0.232 0.768 0.000
M07.50 Arthropathy in ulcerative colitis (Multiple sites)
0.232 0.768 0.000
M07.69 Other enteropathic arthropathies (Site unspecified)
0.232 0.768 0.000
M07.68 Other enteropathic arthropathies (Other)
0.232 0.768 0.000
M07.67 Other enteropathic arthropathies (Ankle and foot)
0.232 0.768 0.000
M07.66 Other enteropathic arthropathies (Lower leg)
0.232 0.768 0.000
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)
0.232 0.768 0.000
M07.64 Other enteropathic arthropathies (Hand)
0.232 0.768 0.000
M07.63 Other enteropathic arthropathies (Forearm)
0.232 0.768 0.000
M07.62 Other enteropathic arthropathies (Upper arm)
0.232 0.768 0.000
M07.61 Other enteropathic arthropathies (Shoulder region)
0.232 0.768 0.000
M07.60 Other enteropathic arthropathies (Multiple sites)
0.232 0.768 0.000
E28.2 Polycystic ovarian syndrome
0.000 0.769 0.230
E13.9 Without complications
0.000 0.769 0.230
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.774 0.226
E56.1 Deficiency of vitamin K
0.000 0.774 0.226
E24.8 Other Cushing's syndrome
0.002 0.775 0.223
E24.2 Drug-induced Cushing's syndrome
0.002 0.777 0.222
E56.9 Vitamin deficiency, unspecified
0.000 0.777 0.223
E56.8 Deficiency of other vitamins
0.000 0.777 0.223
E56.0 Deficiency of vitamin E
0.000 0.777 0.223
E50.9 Vitamin A deficiency, unspecified
0.000 0.779 0.221
E50.8 Other manifestations of vitamin A deficiency
0.000 0.779 0.221
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.779 0.221
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.779 0.221
E50.5 Vitamin A deficiency with night blindness
0.000 0.779 0.221
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.779 0.221
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.779 0.221
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.779 0.221
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.779 0.221
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.779 0.221
E63.9 Nutritional deficiency, unspecified
0.000 0.779 0.221
E63.8 Other specified nutritional deficiencies
0.000 0.779 0.221
E63.1 Imbalance of constituents of food intake
0.000 0.779 0.221
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.779 0.221
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.779 0.221
E64.8 Sequelae of other nutritional deficiencies
0.000 0.779 0.221
E64.3 Sequelae of rickets
0.000 0.779 0.221
E64.2 Sequelae of vitamin C deficiency
0.000 0.779 0.221
E64.1 Sequelae of vitamin A deficiency
0.000 0.779 0.221
E64.0 Sequelae of protein-energy malnutrition
0.000 0.779 0.221
G36.9 Acute disseminated demyelination, unspecified
0.000 0.781 0.218
G36.8 Other specified acute disseminated demyelination
0.000 0.781 0.218
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.781 0.218
E55 Vitamin D deficiency
0.000 0.790 0.209
G36.0 Neuromyelitis optica [Devic]
0.000 0.797 0.203
E23.0 Hypopituitarism
0.000 0.797 0.203
E07.9 Disorder of thyroid, unspecified
0.000 0.801 0.198
E04.0 Non-toxic diffuse goitre
0.000 0.810 0.190
E04.1 Non-toxic single thyroid nodule
0.000 0.811 0.189
E04.8 Other specified non-toxic goitre
0.000 0.814 0.186
E29.1 Testicular hypofunction
0.001 0.815 0.185
E24.0 Pituitary-dependent Cushing's disease
0.002 0.815 0.183
E61 Deficiency of other nutrient elements
0.002 0.844 0.155
E55.0 Rickets, active
0.000 0.850 0.150
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.852 0.148
E11 Non-insulin-dependent diabetes mellitus
0.000 0.859 0.141
M45-M49 Spondylopathies
0.140 0.860 0.000
E11.3 With ophthalmic complications
0.000 0.883 0.117
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.884 0.116
E61.9 Deficiency of nutrient element, unspecified
0.001 0.888 0.111
E61.8 Deficiency of other specified nutrient elements
0.001 0.888 0.111
E61.7 Deficiency of multiple nutrient elements
0.001 0.888 0.111
E61.6 Vanadium deficiency
0.001 0.888 0.111
E61.5 Molybdenum deficiency
0.001 0.888 0.111
E61.4 Chromium deficiency
0.001 0.888 0.111
E61.3 Manganese deficiency
0.001 0.888 0.111
E61.0 Copper deficiency
0.001 0.888 0.111
N20.0 Calculus of kidney
0.106 0.894 0.000
E11.7 With multiple complications
0.000 0.899 0.101
E11.8 With unspecified complications
0.000 0.899 0.101
E11.5 With peripheral circulatory complications
0.000 0.902 0.098
E11.6 With other specified complications
0.000 0.904 0.096
E21.4 Other specified disorders of parathyroid gland
0.000 0.905 0.095
E11.1 With ketoacidosis
0.000 0.905 0.095
M47 Spondylosis
0.095 0.905 0.000
E21.3 Hyperparathyroidism, unspecified
0.000 0.905 0.094
E11.0 With coma
0.000 0.906 0.094
M47.8 Other spondylosis
0.093 0.907 0.000
E21.2 Other hyperparathyroidism
0.000 0.908 0.091
E61.2 Magnesium deficiency
0.002 0.909 0.089
E24.9 Cushing's syndrome, unspecified
0.004 0.911 0.086
M47.82 Other spondylosis (Cervical region)
0.089 0.911 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.088 0.912 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.001 0.916 0.083
M49 Spondylopathies in diseases classified elsewhere
0.082 0.917 0.000
K59.8 Other specified functional intestinal disorders
0.082 0.918 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.918 0.081
E11.2 With renal complications
0.000 0.920 0.080
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.921 0.078
M47.83 Other spondylosis (Cervicothoracic region)
0.077 0.923 0.000
M47.84 Other spondylosis (Thoracic region)
0.074 0.926 0.000
M47.89 Other spondylosis (Site unspecified)
0.073 0.927 0.000
D67 Hereditary factor IX deficiency
0.000 0.927 0.073
M48 Other spondylopathies
0.069 0.931 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.068 0.932 0.000
K90-K93 Other diseases of the digestive system
0.000 0.932 0.068
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.067 0.933 0.000
E66 Obesity
0.000 0.936 0.064
M47.1 Other spondylosis with myelopathy
0.062 0.938 0.000
M46 Other inflammatory spondylopathies
0.061 0.939 0.000
D66 Hereditary factor VIII deficiency
0.000 0.939 0.061
M49.8 Spondylopathy in other diseases classified elsewhere
0.059 0.941 0.000
M49.4 Neuropathic spondylopathy
0.059 0.941 0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere
0.059 0.941 0.000
M49.2 Enterobacterial spondylitis
0.059 0.941 0.000
M49.1 Brucella spondylitis
0.059 0.941 0.000
M49.0 Tuberculosis of spine
0.059 0.941 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.059 0.941 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.059 0.941 0.000
M48.9 Spondylopathy, unspecified
0.057 0.943 0.000
M05-M14 Inflammatory polyarthropathies
0.057 0.943 0.000
D68 Other coagulation defects
0.000 0.944 0.056
M47.85 Other spondylosis (Thoracolumbar region)
0.055 0.945 0.000
E04.9 Non-toxic goitre, unspecified
0.000 0.946 0.054
E55.9 Vitamin D deficiency, unspecified
0.000 0.949 0.051
M48.4 Fatigue fracture of vertebra
0.049 0.951 0.000
M48.3 Traumatic spondylopathy
0.049 0.951 0.000
M48.2 Kissing spine
0.049 0.951 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.049 0.951 0.000
M46.4 Discitis, unspecified
0.049 0.951 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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