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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3129908
log Bayes Factor = 198.273
Chromosome 6   position 32,325,707  (GRCh37) Explore rs3129908 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
L40 Psoriasis
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E14.9 Without complications
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
E14.3 With ophthalmic complications
0.000 0.000 1.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
H36 Retinal disorders in diseases classified elsewhere
0.000 0.000 1.000
H30-H36 Disorders of choroid and retina
0.000 0.001 0.999
J33 Nasal polyp
0.000 0.001 0.999
J33.0 Polyp of nasal cavity
0.000 0.001 0.999
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.001 0.999
L40.5 Arthropathic psoriasis
0.000 0.001 0.999
M07 Psoriatic and enteropathic arthropathies
0.000 0.001 0.999
M35.3 Polymyalgia rheumatica
0.000 0.001 0.999
J40-J47 Chronic lower respiratory diseases
0.000 0.001 0.999
J45 Asthma
0.000 0.001 0.999
Chapter X Diseases of the respiratory system
0.000 0.002 0.998
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.002 0.998
M07.3 Other psoriatic arthropathies
0.000 0.002 0.998
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.002 0.998
Chapter VII Diseases of the eye and adnexa
0.000 0.002 0.998
G35-G37 Demyelinating diseases of the central nervous system
0.996 0.004 0.000
E10.4 With neurological complications
0.000 0.004 0.996
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.004 0.996
G37 Other demyelinating diseases of central nervous system
0.995 0.005 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.994 0.006 0.000
M35 Other systemic involvement of connective tissue
0.000 0.007 0.993
E11.1 With ketoacidosis
0.000 0.007 0.993
J33.9 Nasal polyp, unspecified
0.000 0.007 0.993
L40-L45 Papulosquamous disorders
0.000 0.007 0.993
M20-M25 Other joint disorders
0.000 0.009 0.991
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.009 0.991
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.013 0.987
E10.2 With renal complications
0.000 0.014 0.986
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.017 0.983
J43 Emphysema
0.000 0.019 0.981
K90 Intestinal malabsorption
0.000 0.021 0.979
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.023 0.977
Chapter XI Diseases of the digestive system
0.000 0.026 0.974
M06.3 Rheumatoid nodule
0.000 0.027 0.973
K90-K93 Other diseases of the digestive system
0.000 0.029 0.971
J30-J39 Other diseases of upper respiratory tract
0.000 0.029 0.971
E10.5 With peripheral circulatory complications
0.000 0.030 0.970
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.033 0.967
L40.0 Psoriasis vulgaris
0.000 0.041 0.959
E10.0 With coma
0.000 0.042 0.958
E11.3 With ophthalmic complications
0.000 0.047 0.953
K70-K77 Diseases of liver
0.000 0.048 0.952
J33.8 Other polyp of sinus
0.000 0.050 0.950
K75 Other inflammatory liver diseases
0.000 0.051 0.949
J43.9 Emphysema, unspecified
0.000 0.056 0.944
K75.4 Autoimmune hepatitis
0.000 0.059 0.941
M06.4 Inflammatory polyarthropathy
0.000 0.066 0.934
H53-H54 Visual disturbances and blindness
0.000 0.073 0.927
K75.8 Other specified inflammatory liver diseases
0.000 0.078 0.922
H33 Retinal detachments and breaks
0.000 0.082 0.918
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.082 0.918
M31 Other necrotising vasculopathies
0.000 0.083 0.917
E70-E90 Metabolic disorders
0.000 0.083 0.916
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.084 0.916
J95-J99 Other diseases of the respiratory system
0.000 0.087 0.913
E10.8 With unspecified complications
0.000 0.091 0.909
H54 Blindness and low vision
0.000 0.092 0.908
E50-E64 Other nutritional deficiencies
0.000 0.097 0.903
K73 Chronic hepatitis, not elsewhere classified
0.000 0.099 0.901
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.102 0.898
M35.1 Other overlap syndromes
0.000 0.104 0.896
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.105 0.895
H33.3 Retinal breaks without detachment
0.000 0.106 0.894
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.116 0.884
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.116 0.884
H35 Other retinal disorders
0.000 0.116 0.884
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.117 0.883
E10.6 With other specified complications
0.000 0.117 0.883
K50-K52 Noninfective enteritis and colitis
0.002 0.119 0.879
J95.0 Tracheostomy malfunction
0.000 0.121 0.879
E06 Thyroiditis
0.000 0.125 0.875
E86 Volume depletion
0.000 0.126 0.874
H34 Retinal vascular occlusions
0.000 0.129 0.871
K50 Crohn's disease [regional enteritis]
0.000 0.130 0.870
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.131 0.869
E53 Deficiency of other B group vitamins
0.000 0.131 0.869
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.132 0.868
H33.4 Traction detachment of retina
0.000 0.136 0.864
E03.8 Other specified hypothyroidism
0.000 0.137 0.863
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.138 0.862
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.139 0.861
M31.6 Other giant cell arteritis
0.000 0.140 0.860
D64.9 Anaemia, unspecified
0.000 0.141 0.859
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.142 0.858
H35.4 Peripheral retinal degeneration
0.000 0.142 0.858
E11.2 With renal complications
0.000 0.143 0.857
D60-D64 Aplastic and other anaemias
0.000 0.144 0.856
H54.7 Unspecified visual loss
0.000 0.144 0.856
D64 Other anaemias
0.000 0.145 0.855
E11.8 With unspecified complications
0.000 0.146 0.854
E53.8 Deficiency of other specified B group vitamins
0.000 0.146 0.854
M24 Other specific joint derangements
0.000 0.148 0.852
E14.6 With other specified complications
0.000 0.153 0.847
L80 Vitiligo
0.000 0.153 0.847
J46 Status asthmaticus
0.000 0.154 0.846
E88 Other metabolic disorders
0.000 0.157 0.843
G37.8 Other specified demyelinating diseases of central nervous system
0.843 0.157 0.000
K82 Other diseases of gallbladder
0.000 0.157 0.843
J86 Pyothorax
0.000 0.157 0.843
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.159 0.840
J43.2 Centrilobular emphysema
0.000 0.161 0.839
E14.1 With ketoacidosis
0.000 0.163 0.837
K81 Cholecystitis
0.000 0.164 0.836
M65-M68 Disorders of synovium and tendon
0.000 0.167 0.833
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.167 0.833
E14.8 With unspecified complications
0.000 0.167 0.833
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.169 0.831
L40.8 Other psoriasis
0.000 0.169 0.831
H35.8 Other specified retinal disorders
0.000 0.170 0.830
M12 Other specific arthropathies
0.000 0.170 0.830
L40.1 Generalised pustular psoriasis
0.000 0.171 0.829
K50.8 Other Crohn's disease
0.000 0.172 0.828
K50.1 Crohn's disease of large intestine
0.000 0.173 0.827
K82.8 Other specified diseases of gallbladder
0.000 0.174 0.826
E16.1 Other hypoglycaemia
0.000 0.176 0.824
H54.0 Blindness, both eyes
0.000 0.176 0.824
L10-L14 Bullous disorders
0.000 0.177 0.823
M06.34 Rheumatoid nodule (Hand)
0.000 0.178 0.822
E14.2 Withrenal complications
0.000 0.179 0.821
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.186 0.814
E78.2 Mixed hyperlipidaemia
0.000 0.188 0.812
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.188 0.812
M34 Systemic sclerosis
0.000 0.192 0.808
M24.1 Other articular cartilage disorders
0.000 0.194 0.806
L92 Granulomatous disorders of skin and subcutaneous tissue
0.000 0.195 0.805
K81.1 Chronic cholecystitis
0.000 0.196 0.804
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.196 0.804
E27 Other disorders of adrenal gland
0.000 0.198 0.802
E20-E35 Disorders of other endocrine glands
0.000 0.198 0.802
J39 Other diseases of upper respiratory tract
0.000 0.202 0.798
D50-D53 Nutritional anaemias
0.000 0.203 0.797
E27.1 Primary adrenocortical insufficiency
0.000 0.206 0.794
E78.4 Other hyperlipidaemia
0.000 0.207 0.793
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.209 0.791
J43.8 Other emphysema
0.000 0.210 0.790
M45-M49 Spondylopathies
0.000 0.213 0.787
K81.9 Cholecystitis, unspecified
0.000 0.216 0.784
L90 Atrophic disorders of skin
0.000 0.217 0.783
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.000 0.220 0.780
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.221 0.779
M24.16 Other articular cartilage disorders (Lower leg)
0.000 0.222 0.778
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.223 0.777
L40.3 Pustulosis palmaris et plantaris
0.000 0.225 0.775
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.228 0.772
E83.1 Disorders of iron metabolism
0.767 0.233 0.000
J33.1 Polypoid sinus degeneration
0.000 0.239 0.760
J86.0 Pyothorax with fistula
0.000 0.240 0.759
E06.3 Autoimmune thyroiditis
0.000 0.243 0.757
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.244 0.756
K90.9 Intestinal malabsorption, unspecified
0.000 0.244 0.756
M30 Polyarteritis nodosa and related conditions
0.000 0.245 0.755
E89.0 Postprocedural hypothyroidism
0.000 0.246 0.754
L90.0 Lichen sclerosus et atrophicus
0.000 0.246 0.754
H54.2 Low vision, both eyes
0.000 0.248 0.752
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.000 0.248 0.752
H35.2 Other proliferative retinopathy
0.000 0.249 0.751
D50 Iron deficiency anaemia
0.000 0.250 0.750
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.253 0.747
M45 Ankylosing spondylitis
0.000 0.253 0.747
G36 Other acute disseminated demyelination
0.746 0.254 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.257 0.743
H20 Iridocyclitis
0.000 0.258 0.742
K71 Toxic liver disease
0.000 0.260 0.740
D50.9 Iron deficiency anaemia, unspecified
0.000 0.260 0.740
M80-M85 Disorders of bone density and structure
0.000 0.261 0.739
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.261 0.739
M35.2 Behcet's disease
0.000 0.263 0.737
J86.9 Pyothorax without fistula
0.000 0.265 0.735
K73.9 Chronic hepatitis, unspecified
0.000 0.266 0.734
E78.6 Lipoprotein deficiency
0.000 0.267 0.732
M24.11 Other articular cartilage disorders (Shoulder region)
0.000 0.268 0.732
K50.0 Crohn's disease of small intestine
0.000 0.268 0.732
K82.3 Fistula of gallbladder
0.000 0.269 0.731
M24.7 Protrusio acetabuli
0.000 0.273 0.727
M35.7 Hypermobility syndrome
0.000 0.275 0.725
H20.0 Acute and subacute iridocyclitis
0.000 0.276 0.724
H34.9 Retinal vascular occlusion, unspecified
0.000 0.278 0.722
H54.1 Blindness, one eye, low vision, other eye
0.000 0.279 0.721
L94 Other localised connective tissue disorders
0.000 0.280 0.720
J39.8 Other specified diseases of upper respiratory tract
0.000 0.280 0.720
L84 Corns and callosities
0.000 0.280 0.720
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.281 0.719
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.283 0.717
M86-M90 Other osteopathies
0.000 0.283 0.717
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.283 0.717
M07.5 Arthropathy in ulcerative colitis
0.000 0.284 0.716
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.284 0.716
M07.2 Psoriatic spondylitis
0.000 0.284 0.716
M07.1 Arthritis mutilans
0.000 0.284 0.716
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.284 0.716
M07.38 Other psoriatic arthropathies (Other)
0.000 0.284 0.716
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.284 0.716
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.284 0.716
M65 Synovitis and tenosynovitis
0.000 0.286 0.714
G37.5 Concentric sclerosis [Balo]
0.714 0.286 0.000
G37.4 Subacute necrotising myelitis
0.714 0.286 0.000
G37.2 Central pontine myelinolysis
0.714 0.286 0.000
G37.1 Central demyelination of corpus callosum
0.714 0.286 0.000
G37.0 Diffuse sclerosis
0.714 0.286 0.000
M80 Osteoporosis with pathological fracture
0.000 0.286 0.714
M91-M94 Chondropathies
0.000 0.287 0.713
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.288 0.712
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.288 0.712
M35.5 Multifocal fibrosclerosis
0.000 0.288 0.712
H43-H45 Disorders of vitreous body and globe
0.000 0.288 0.712
L44 Other papulosquamous disorders
0.000 0.288 0.712
L41 Parapsoriasis
0.000 0.288 0.712
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.288 0.712
E11.0 With coma
0.000 0.289 0.711
E83 Disorders of mineral metabolism
0.677 0.289 0.034
H30 Chorioretinal inflammation
0.000 0.290 0.710
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.708 0.292 0.000
L40.4 Guttate psoriasis
0.000 0.295 0.705
M80.9 Unspecified osteoporosis with pathological fracture
0.000 0.296 0.704
M31.7 Microscopic polyangiitis
0.000 0.296 0.704
J43.1 Panlobular emphysema
0.000 0.297 0.703
J43.0 MacLeod's syndrome
0.000 0.297 0.703
H34.1 Central retinal artery occlusion
0.000 0.297 0.703
E88.2 Lipomatosis, not elsewhere classified
0.000 0.298 0.702
K90.3 Pancreatic steatorrhoea
0.000 0.298 0.702
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.298 0.702
K90.1 Tropical sprue
0.000 0.298 0.702
J44 Other chronic obstructive pulmonary disease
0.000 0.298 0.702
H33.1 Retinoschisis and retinal cysts
0.000 0.300 0.700
E07 Other disorders of thyroid
0.000 0.300 0.700
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.301 0.699
E40-E46 Malnutrition
0.000 0.301 0.699
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.302 0.698
M06.38 Rheumatoid nodule (Other)
0.000 0.302 0.698
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.302 0.698
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.302 0.698
M06.33 Rheumatoid nodule (Forearm)
0.000 0.302 0.698
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.302 0.698
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.303 0.696
M05.2 Rheumatoid vasculitis
0.000 0.305 0.695
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.307 0.693
H35.6 Retinal haemorrhage
0.000 0.307 0.693
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.308 0.692
M12.3 Palindromic rheumatism
0.000 0.309 0.691
M06.1 Adult-onset Still's disease
0.000 0.309 0.691
H34.2 Other retinal artery occlusions
0.000 0.309 0.691
E70 Disorders of aromatic amino-acid metabolism
0.000 0.309 0.690
M15-M19 Arthrosis
0.000 0.310 0.690
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.311 0.689
M00-M03 Infectious arthropathies
0.000 0.312 0.688
M49 Spondylopathies in diseases classified elsewhere
0.000 0.314 0.686
E06.5 Other chronic thyroiditis
0.000 0.316 0.684
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.316 0.684
L12 Pemphigoid
0.000 0.316 0.684
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.317 0.683
K77 Liver disorders in diseases classified elsewhere
0.000 0.318 0.682
M18 Arthrosis of first carpometacarpal joint
0.000 0.318 0.682
K75.2 Nonspecific reactive hepatitis
0.000 0.319 0.680
K75.1 Phlebitis of portal vein
0.000 0.319 0.680
H54.9 Unspecified visual impairment (binocular)
0.000 0.321 0.679
M31.8 Other specified necrotising vasculopathies
0.000 0.321 0.679
M07.6 Other enteropathic arthropathies
0.000 0.324 0.676
L13 Other bullous disorders
0.000 0.324 0.676
L92.0 Granuloma annulare
0.000 0.324 0.676
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.326 0.674
E56 Other vitamin deficiencies
0.000 0.327 0.672
E11.5 With peripheral circulatory complications
0.000 0.328 0.672
E03.1 Congenital hypothyroidism without goitre
0.000 0.329 0.671
E14.5 With peripheral circulatory complications
0.000 0.330 0.670
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.330 0.670
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.330 0.670
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.330 0.670
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.330 0.670
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.330 0.670
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.330 0.670
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.330 0.670
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.330 0.670
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.330 0.670
M18.1 Other primary arthrosis of first carpometacarpal joint
0.000 0.330 0.670
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.000 0.332 0.668
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)
0.000 0.334 0.666
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.336 0.664
M34.1 CR(E)ST syndrome
0.000 0.336 0.664
M32 Systemic lupus erythematosus
0.000 0.338 0.662
H54.5 Low vision, one eye
0.000 0.339 0.661
E51 Thiamine deficiency
0.000 0.339 0.661
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.339 0.661
L85 Other epidermal thickening
0.000 0.340 0.660
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.340 0.660
J45.1 Nonallergic asthma
0.000 0.341 0.658
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.342 0.658
M31.4 Aortic arch syndrome [Takayasu]
0.000 0.342 0.657
M31.2 Lethal midline granuloma
0.000 0.342 0.657
E77 Disorders of glycoprotein metabolism
0.000 0.343 0.657
E76 Disorders of glycosaminoglycan metabolism
0.000 0.343 0.657
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.343 0.657
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.343 0.657
M24.0 Loose body in joint
0.000 0.345 0.655
J96 Respiratory failure, not elsewhere classified
0.000 0.345 0.654
M31.3 Wegener's granulomatosis
0.000 0.346 0.654
E88.8 Other specified metabolic disorders
0.000 0.346 0.654
M06.8 Other specified rheumatoid arthritis
0.000 0.347 0.653
E74 Other disorders of carbohydrate metabolism
0.000 0.347 0.653
M80.98 Unspecified osteoporosis with pathological fracture (Other)
0.000 0.348 0.652
M31.1 Thrombotic microangiopathy
0.000 0.348 0.651
H54.3 Unqualified visual loss, both eyes
0.000 0.349 0.651
M24.6 Ankylosis of joint
0.000 0.350 0.650
D62 Acute posthaemorrhagic anaemia
0.000 0.350 0.650
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.350 0.649
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.353 0.647
E63 Other nutritional deficiencies
0.000 0.353 0.647
E50 Vitamin A deficiency
0.000 0.353 0.647
E60 Dietary zinc deficiency
0.000 0.353 0.647
E59 Dietary selenium deficiency
0.000 0.353 0.647
E52 Niacin deficiency [pellagra]
0.000 0.353 0.647
D51 Vitamin B12 deficiency anaemia
0.000 0.354 0.646
E14.4 With neurological complications
0.000 0.354 0.646
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.354 0.646
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.354 0.646
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.355 0.645
H54.6 Unqualified visual loss, one eye
0.000 0.356 0.644
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.000 0.356 0.644
L87 Transepidermal elimination disorders
0.000 0.356 0.644
L86 Keratoderma in diseases classified elsewhere
0.000 0.356 0.644
M24.5 Contracture of joint
0.000 0.358 0.642
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.363 0.637
M24.75 Protrusio acetabuli-Pelvic/thigh
0.000 0.363 0.637
M67 Other disorders of synovium and tendon
0.000 0.364 0.636
E06.9 Thyroiditis, unspecified
0.000 0.365 0.634
J95.5 Postprocedural subglottic stenosis
0.000 0.366 0.634
J95.4 Mendelson's syndrome
0.000 0.366 0.634
J95.3 Chronic pulmonary insufficiency following surgery
0.000 0.366 0.634
J95.2 Acute pulmonary insufficiency following nonthoracic surgery
0.000 0.366 0.634
J95.1 Acute pulmonary insufficiency following thoracic surgery
0.000 0.366 0.634
H35.1 Retinopathy of prematurity
0.000 0.366 0.634
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.000 0.366 0.633
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.369 0.631
M06.0 Seronegative rheumatoid arthritis
0.000 0.369 0.631
J39.0 Retropharyngeal and parapharyngeal abscess
0.000 0.370 0.630
E06.4 Drug-induced thyroiditis
0.000 0.372 0.628
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.372 0.628
E06.1 Subacute thyroiditis
0.000 0.372 0.628
E06.0 Acute thyroiditis
0.000 0.372 0.628
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.373 0.627
E54 Ascorbic acid deficiency
0.000 0.374 0.626
E11.4 With neurological complications
0.000 0.375 0.625
H34.0 Transient retinal artery occlusion
0.000 0.376 0.624
E72 Other disorders of amino-acid metabolism
0.000 0.376 0.624
H10-H13 Disorders of conjunctiva
0.000 0.376 0.624
E78.8 Other disorders of lipoprotein metabolism
0.000 0.376 0.623
E53.1 Pyridoxine deficiency
0.000 0.377 0.623
E53.0 Riboflavin deficiency
0.000 0.377 0.623
L85.8 Other specified epidermal thickening
0.000 0.377 0.623
J20-J22 Other acute lower respiratory infections
0.000 0.377 0.623
M82 Osteoporosis in diseases classified elsewhere
0.000 0.377 0.623
L94.2 Calcinosis cutis
0.000 0.378 0.622
M60-M63 Disorders of muscles
0.000 0.378 0.621
M34.8 Other forms of systemic sclerosis
0.000 0.379 0.621
M12.2 Villonodular synovitis (pigmented)
0.000 0.380 0.620
E61 Deficiency of other nutrient elements
0.000 0.380 0.620
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.000 0.380 0.620
M86 Osteomyelitis
0.000 0.381 0.619
E78.3 Hyperchylomicronaemia
0.000 0.382 0.618
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.383 0.616
E83.3 Disorders of phosphorus metabolism
0.609 0.384 0.007
L92.2 Granuloma faciale [eosinophilic granuloma of skin]
0.000 0.384 0.615
M14 Arthropathies in other diseases classified elsewhere
0.000 0.385 0.615
H35.7 Separation of retinal layers
0.000 0.385 0.615
M49.5 Collapsed vertebra in diseases classified elsewhere
0.000 0.386 0.614
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.386 0.614
E28 Ovarian dysfunction
0.000 0.386 0.614
J41 Simple and mucopurulent chronic bronchitis
0.000 0.387 0.613
D64.4 Congenital dyserythropoietic anaemia
0.000 0.387 0.613
D64.3 Other sideroblastic anaemias
0.000 0.387 0.613
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.387 0.613
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.387 0.613
D64.0 Hereditary sideroblastic anaemia
0.000 0.387 0.613
M24.9 Joint derangement, unspecified
0.000 0.389 0.611
J37 Chronic laryngitis and laryngotracheitis
0.000 0.390 0.610
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.000 0.390 0.610
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.393 0.607
M94 Other disorders of cartilage
0.000 0.393 0.607
E79 Disorders of purine and pyrimidine metabolism
0.000 0.394 0.605
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.000 0.394 0.606
K82.2 Perforation of gallbladder
0.000 0.396 0.604
E83.5 Disorders of calcium metabolism
0.601 0.398 0.001
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.401 0.599
M24.15 Other articular cartilage disorders (Pelvic region and thigh)
0.000 0.401 0.599
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.402 0.598
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.402 0.598
M12.5 Traumatic arthropathy
0.000 0.403 0.597
E73 Lactose intolerance
0.000 0.403 0.597
M12.39 Palindromic rheumatism (Site unspecified)
0.000 0.403 0.596
L95 Vasculitis limited to skin, not elsewhere classified
0.000 0.404 0.596
M12.4 Intermittent hydrarthrosis
0.000 0.405 0.595
M12.1 Kaschin-Beck disease
0.000 0.405 0.595
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.000 0.405 0.595
M12.8 Other specific arthropathies, not elsewhere classified
0.000 0.405 0.595
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.405 0.595
K72 Hepatic failure, not elsewhere classified
0.000 0.406 0.594
D53 Other nutritional anaemias
0.000 0.407 0.593
M35.8 Other specified systemic involvement of connective tissue
0.000 0.408 0.592
J95.9 Postprocedural respiratory disorder, unspecified
0.000 0.408 0.592
E83.9 Disorder of mineral metabolism, unspecified
0.572 0.409 0.018
L10 Pemphigus
0.000 0.410 0.590
L14 Bullous disorders in diseases classified elsewhere
0.000 0.410 0.590
M30.0 Polyarteritis nodosa
0.000 0.412 0.588
K82.9 Disease of gallbladder, unspecified
0.000 0.413 0.587
M31.9 Necrotising vasculopathy, unspecified
0.000 0.414 0.586
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.000 0.416 0.584
H20.1 Chronic iridocyclitis
0.000 0.417 0.583
L12.1 Cicatricial pemphigoid
0.000 0.417 0.583
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.419 0.581
E78.1 Pure hyperglyceridaemia
0.000 0.419 0.581
E11.6 With other specified complications
0.000 0.420 0.580
M34.2 Systemic sclerosis induced by drugs and chemicals
0.000 0.421 0.579
K71.0 Toxic liver disease with cholestasis
0.000 0.421 0.579
H16 Keratitis
0.000 0.421 0.579
M34.0 Progressive systemic sclerosis
0.000 0.422 0.578
M24.19 Other articular cartilage disorders (Site unspecified)
0.000 0.422 0.578
M24.18 Other articular cartilage disorders (Other)
0.000 0.422 0.578
M24.14 Other articular cartilage disorders (Hand)
0.000 0.422 0.578
M24.12 Other articular cartilage disorders (Upper arm)
0.000 0.422 0.578
M24.10 Other articular cartilage disorders (Multiple sites)
0.000 0.422 0.578
L92.1 Necrobiosis lipoidica, not elsewhere classified
0.000 0.423 0.577
J45.8 Mixed asthma
0.000 0.423 0.577
E24 Cushing's syndrome
0.000 0.424 0.576
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.424 0.575
J99.0 Rheumatoid lung disease
0.000 0.425 0.575
E27.5 Adrenomedullary hyperfunction
0.000 0.425 0.575
E27.0 Other adrenocortical overactivity
0.000 0.425 0.575
K82.0 Obstruction of gallbladder
0.000 0.425 0.575
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.425 0.575
E32 Diseases of thymus
0.000 0.425 0.575
E31 Polyglandular dysfunction
0.000 0.425 0.575
E30 Disorders of puberty, not elsewhere classified
0.000 0.425 0.575
L90.8 Other atrophic disorders of skin
0.000 0.427 0.573

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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