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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant cluster associations

Hospitalization Episode Statistics (HES)

Cluster X0279
log Bayes Factor = 52.8832
contains 2 variants:
rs13107325
lBF = 35.350
Chr 4 : 103,188,709
rs7140889
lBF = 14.912
Chr14 : 31,153,199
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M15-M19 Arthrosis
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
M16.9 Coxarthrosis, unspecified
1.000 0.000 0.000
M19.9 Arthrosis, unspecified
1.000 0.000 0.000
M16 Coxarthrosis [arthrosis of hip]
1.000 0.000 0.000
M75 Shoulder lesions
1.000 0.000 0.000
M19 Other arthrosis
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
M70-M79 Other soft tissue disorders
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Z91 Personal history of risk-factors, not elsewhere classified
1.000 0.000 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
1.000 0.000 0.000
M20 Acquired deformities of fingers and toes
1.000 0.000 0.000
M75.1 Rotator cuff syndrome
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.999 0.001 0.000
M05-M14 Inflammatory polyarthropathies
0.999 0.001 0.000
S60-S69 Injuries to the wrist and hand
0.999 0.001 0.000
M13 Other arthritis
0.999 0.001 0.000
Chapter XI Diseases of the digestive system
0.999 0.001 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.999 0.001 0.000
M13.9 Arthritis, unspecified
0.999 0.001 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.999 0.001 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.999 0.001 0.000
M25 Other joint disorders, not elsewhere classified
0.999 0.001 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
E11 Non-insulin-dependent diabetes mellitus
0.999 0.001 0.000
M17 Gonarthrosis [arthrosis of knee]
0.998 0.002 0.000
C15-C26 Malignant neoplasms of digestive organs
0.998 0.002 0.000
E10-E14 Diabetes mellitus
0.998 0.002 0.000
K21 Gastro-oesophageal reflux disease
0.998 0.002 0.000
Z96 Presence of other functional implants
0.997 0.003 0.000
K21.9 Gastro-oesophageal reflux disease without oesophagitis
0.997 0.003 0.000
K22 Other diseases of oesophagus
0.997 0.003 0.000
M17.9 Gonarthrosis, unspecified
0.996 0.004 0.000
M45-M49 Spondylopathies
0.996 0.004 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.996 0.004 0.000
E11.9 Without complications
0.995 0.005 0.000
Chapter XXI Factors influencing health status and contact with health services
0.995 0.005 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.994 0.006 0.000
K40-K46 Hernia
0.994 0.006 0.000
F60-F69 Disorders of adult personality and behaviour
0.994 0.006 0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene
0.994 0.006 0.000
K44 Diaphragmatic hernia
0.994 0.006 0.000
M20.1 Hallux valgus (acquired)
0.993 0.007 0.000
Z96.6 Presence of orthopaedic joint implants
0.992 0.008 0.000
G40-G47 Episodic and paroxysmal disorders
0.991 0.009 0.000
G47 Sleep disorders
0.989 0.011 0.000
K22.1 Ulcer of oesophagus
0.988 0.012 0.000
F60 Specific personality disorders
0.988 0.012 0.000
M25.7 Osteophyte
0.987 0.013 0.000
C50-C50 Malignant neoplasm of breast
0.987 0.013 0.000
M22 Disorders of patella
0.986 0.014 0.000
Z91.5 Personal history of self-harm
0.986 0.014 0.000
M75.0 Adhesive capsulitis of shoulder
0.985 0.015 0.000
Z93 Artificial opening status
0.985 0.015 0.000
E11.3 With ophthalmic complications
0.985 0.015 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.985 0.015 0.000
G47.3 Sleep apnoea
0.984 0.016 0.000
M20.4 Other hammer toe(s) (acquired)
0.982 0.018 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.981 0.019 0.000
M40-M43 Deforming dorsopathies
0.979 0.021 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.978 0.022 0.000
M16.7 Other secondary coxarthrosis
0.978 0.022 0.000
C50 Malignant neoplasm of breast
0.978 0.022 0.000
M86-M90 Other osteopathies
0.977 0.023 0.000
M77 Other enthesopathies
0.977 0.023 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.974 0.026 0.000
Z89 Acquired absence of limb
0.969 0.031 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.969 0.031 0.000
C16 Malignant neoplasm of stomach
0.968 0.032 0.000
F30-F39 Mood [affective] disorders
0.967 0.033 0.000
M50-M54 Other dorsopathies
0.966 0.034 0.000
F60.9 Personality disorder, unspecified
0.965 0.035 0.000
C79 Secondary malignant neoplasm of other sites
0.965 0.035 0.000
M22.4 Chondromalacia patellae
0.964 0.036 0.000
Z93.3 Colostomy status
0.964 0.036 0.000
K22.8 Other specified diseases of oesophagus
0.964 0.036 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.964 0.036 0.000
S64 Injury of nerves at wrist and hand level
0.961 0.039 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.957 0.043 0.000
M46 Other inflammatory spondylopathies
0.956 0.044 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.956 0.044 0.000
M25.76 Osteophyte (Lower leg)
0.955 0.045 0.000
M80-M85 Disorders of bone density and structure
0.954 0.046 0.000
C50.1 Central portion of breast
0.952 0.048 0.000
S10-S19 Injuries to the neck
0.951 0.049 0.000
M65-M68 Disorders of synovium and tendon
0.949 0.051 0.000
S61 Open wound of wrist and hand
0.949 0.051 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.946 0.054 0.000
Z97 Presence of other devices
0.945 0.055 0.000
M17.0 Primary gonarthrosis, bilateral
0.944 0.056 0.000
F99-F99 Unspecified mental disorder
0.944 0.056 0.000
E65-E68 Obesity and other hyperalimentation
0.943 0.057 0.000
M41 Scoliosis
0.940 0.060 0.000
M45 Ankylosing spondylitis
0.939 0.061 0.000
M77.1 Lateral epicondylitis
0.937 0.063 0.000
Z96.8 Presence of other specified functional implants
0.935 0.065 0.000
C78.0 Secondary malignant neoplasm of lung
0.934 0.066 0.000
F60.3 Emotionally unstable personality disorder
0.933 0.067 0.000
E11.4 With neurological complications
0.932 0.068 0.000
F31 Bipolar affective disorder
0.932 0.068 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.932 0.068 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.932 0.068 0.000
Chapter XX External causes of morbidity and mortality
0.928 0.072 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.928 0.072 0.000
C15 Malignant neoplasm of oesophagus
0.925 0.075 0.000
C50.8 Overlapping lesion of breast
0.925 0.075 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.924 0.076 0.000
Z89.4 Acquired absence of foot and ankle
0.918 0.082 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.917 0.083 0.000
S64.4 Injury of digital nerve of other finger
0.917 0.083 0.000
M20.3 Other deformity of hallux (acquired)
0.916 0.084 0.000
M65 Synovitis and tenosynovitis
0.916 0.084 0.000
G47.9 Sleep disorder, unspecified
0.916 0.084 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.915 0.085 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.915 0.085 0.000
M75.5 Bursitis of shoulder
0.914 0.086 0.000
M25.5 Pain in joint
0.914 0.086 0.000
M41.9 Scoliosis, unspecified
0.913 0.087 0.000
M54 Dorsalgia
0.912 0.088 0.000
M19.0 Primary arthrosis of other joints
0.910 0.090 0.000
C16.9 Stomach, unspecified
0.910 0.090 0.000
S61.1 Open wound of finger(s) with damage to nail
0.910 0.090 0.000
K22.4 Dyskinesia of oesophagus
0.909 0.091 0.000
M77.12 Lateral epicondylitis (Upper arm)
0.908 0.092 0.000
S62 Fracture at wrist and hand level
0.906 0.094 0.000
E66 Obesity
0.904 0.096 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.904 0.096 0.000
F99 Mental disorder, not otherwise specified
0.904 0.096 0.000
V80-V89 Other land transport accidents
0.900 0.100 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.900 0.100 0.000
M35 Other systemic involvement of connective tissue
0.898 0.102 0.000
M87 Osteonecrosis
0.896 0.104 0.000
M40 Kyphosis and lordosis
0.896 0.104 0.000
Z97.8 Presence of other specified devices
0.892 0.108 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.889 0.111 0.000
E66.8 Other obesity
0.888 0.112 0.000
Z90.8 Acquired absence of other organs
0.887 0.113 0.000
Chapter VIII Diseases of the ear and mastoid process
0.887 0.113 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.886 0.114 0.000
T92 Sequelae of injuries of upper limb
0.885 0.115 0.000
C25 Malignant neoplasm of pancreas
0.885 0.115 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.884 0.116 0.000
E20-E35 Disorders of other endocrine glands
0.882 0.118 0.000
T91 Sequelae of injuries of neck and trunk
0.882 0.118 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.880 0.120 0.000
M50 Cervical disk disorders
0.880 0.120 0.000
M77.9 Enthesopathy, unspecified
0.876 0.124 0.000
M54.5 Low back pain
0.876 0.124 0.000
F33 Recurrent depressive disorder
0.876 0.124 0.000
M19.94 Arthrosis, unspecified (Hand)
0.874 0.126 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.873 0.127 0.000
M15 Polyarthrosis
0.870 0.130 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.870 0.130 0.000
M35.3 Polymyalgia rheumatica
0.870 0.130 0.000
T39.0 Salicylates
0.869 0.131 0.000
H65-H75 Diseases of middle ear and mastoid
0.868 0.132 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.868 0.132 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.866 0.134 0.000
V89.2 Person injured in unspecified motor-vehicle accident, traffic
0.865 0.135 0.000
M54.56 Low back pain (Lumbar region)
0.865 0.135 0.000
M23 Internal derangement of knee
0.865 0.135 0.000
K27 Peptic ulcer, site unspecified
0.864 0.136 0.000
G90-G99 Other disorders of the nervous system
0.864 0.136 0.000
M89 Other disorders of bone
0.864 0.136 0.000
F80-F89 Disorders of psychological development
0.863 0.137 0.000
M80 Osteoporosis with pathological fracture
0.862 0.138 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.860 0.140 0.000
M07 Psoriatic and enteropathic arthropathies
0.860 0.140 0.000
G58 Other mononeuropathies
0.857 0.143 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.854 0.146 0.000
T98 Sequelae of other and unspecified effects of external causes
0.854 0.146 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.853 0.147 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.853 0.147 0.000
Z99.8 Dependence on other enabling machines and devices
0.853 0.147 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.853 0.147 0.000
M25.4 Effusion of joint
0.853 0.147 0.000
M87.9 Osteonecrosis, unspecified
0.852 0.148 0.000
M25.51 Pain in joint (Shoulder region)
0.851 0.149 0.000
Z93.1 Gastrostomy status
0.847 0.153 0.000
G20-G26 Extrapyramidal and movement disorders
0.847 0.153 0.000
M47 Spondylosis
0.842 0.158 0.000
S61.7 Multiple open wounds of wrist and hand
0.841 0.159 0.000
M25.9 Joint disorder, unspecified
0.838 0.162 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.838 0.162 0.000
S68 Traumatic amputation of wrist and hand
0.837 0.163 0.000
M16.0 Primary coxarthrosis, bilateral
0.837 0.163 0.000
G62 Other polyneuropathies
0.836 0.164 0.000
M40.2 Other and unspecified kyphosis
0.836 0.164 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.835 0.165 0.000
T39.1 4-Aminophenol derivatives
0.835 0.165 0.000
F41 Other anxiety disorders
0.832 0.168 0.000
M49 Spondylopathies in diseases classified elsewhere
0.831 0.168 0.000
Z96.9 Presence of functional implant, unspecified
0.831 0.169 0.000
H74 Other disorders of middle ear and mastoid
0.830 0.170 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.829 0.171 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.829 0.171 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.828 0.172 0.000
M25.8 Other specified joint disorders
0.828 0.172 0.000
Z81 Family history of mental and behavioural disorders
0.827 0.173 0.000
M17.3 Other posttraumatic gonarthrosis
0.827 0.173 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.826 0.174 0.000
H66 Suppurative and unspecified otitis media
0.825 0.175 0.000
S40-S49 Injuries to the shoulder and upper arm
0.825 0.175 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.825 0.175 0.000
C16.1 Fundus of stomach
0.823 0.177 0.000
S10 Superficial injury of neck
0.823 0.177 0.000
M06 Other rheumatoid arthritis
0.819 0.181 0.000
M84 Disorders of continuity of bone
0.819 0.181 0.000
Z93.2 Ileostomy status
0.819 0.181 0.000
G82 Paraplegia and tetraplegia
0.818 0.182 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.818 0.182 0.000
M54.2 Cervicalgia
0.816 0.184 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.815 0.185 0.000
C15.9 Oesophagus, unspecified
0.815 0.185 0.000
W50-W64 Exposure to animate mechanical forces
0.815 0.185 0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)
0.815 0.185 0.000
Z90.5 Acquired absence of kidney
0.813 0.187 0.000
M25.77 Osteophyte (Ankle and foot)
0.812 0.188 0.000
G43 Migraine
0.812 0.188 0.000
M91-M94 Chondropathies
0.812 0.188 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.810 0.190 0.000
M13.0 Polyarthritis, unspecified
0.809 0.191 0.000
C21 Malignant neoplasm of anus and anal canal
0.809 0.191 0.000
M75.3 Calcific tendinitis of shoulder
0.809 0.191 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.807 0.193 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.806 0.194 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.806 0.194 0.000
M22.0 Recurrent dislocation of patella
0.806 0.194 0.000
K20 Oesophagitis
0.806 0.194 0.000
Z93.5 Cystostomy status
0.805 0.195 0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.804 0.196 0.000
C78.2 Secondary malignant neoplasm of pleura
0.803 0.197 0.000
F69 Unspecified disorder of adult personality and behaviour
0.802 0.198 0.000
M90 Osteopathies in diseases classified elsewhere
0.802 0.198 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.801 0.199 0.000
M81 Osteoporosis without pathological fracture
0.801 0.199 0.000
C64-C68 Malignant neoplasms of urinary tract
0.800 0.200 0.000
C15.5 Lower third of oesophagus
0.799 0.201 0.000
S90-S99 Injuries to the ankle and foot
0.797 0.203 0.000
M22.3 Other derangements of patella
0.797 0.203 0.000
Z91.8 Personal history of other specified risk-factors, not elsewhere classified
0.797 0.203 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.796 0.204 0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)
0.794 0.206 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.794 0.206 0.000
C25.2 Tail of pancreas
0.793 0.207 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.793 0.207 0.000
G25 Other extrapyramidal and movement disorders
0.793 0.207 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.792 0.208 0.000
G95 Other diseases of spinal cord
0.791 0.209 0.000
M19.00 Primary arthrosis of other joints (Multiple sites)
0.790 0.210 0.000
F41.9 Anxiety disorder, unspecified
0.790 0.210 0.000
E29 Testicular dysfunction
0.790 0.210 0.000
X60-X84 Intentional self-harm
0.789 0.211 0.000
M50.2 Other cervical disk displacement
0.788 0.212 0.000
T92.0 Sequelae of open wound of upper limb
0.786 0.214 0.000
C50.5 Lower-outer quadrant of breast
0.786 0.214 0.000
S14 Injury of nerves and spinal cord at neck level
0.785 0.214 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.785 0.215 0.000
Z97.1 Presence of artificial limb (complete)(partial)
0.785 0.215 0.000
Z97.2 Presence of dental prosthetic device (complete)(partial)
0.784 0.215 0.000
F34 Persistent mood [affective] disorders
0.784 0.216 0.000
M23.8 Other internal derangements of knee
0.784 0.216 0.000
K41 Femoral hernia
0.783 0.217 0.000
Z96.2 Presence of otological and audiological implants
0.782 0.218 0.000
C22.0 Liver cell carcinoma
0.782 0.218 0.000
M75.9 Shoulder lesion, unspecified
0.781 0.219 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.781 0.219 0.000
Z99.3 Dependence on wheelchair
0.780 0.220 0.000
G62.9 Polyneuropathy, unspecified
0.780 0.220 0.000
S19 Other and unspecified injuries of neck
0.780 0.220 0.000
F31.9 Bipolar affective disorder, unspecified
0.779 0.221 0.000
C16.2 Body of stomach
0.779 0.221 0.000
S61.8 Open wound of other parts of wrist and hand
0.778 0.222 0.000
S64.2 Injury of radial nerve at wrist and hand level
0.778 0.222 0.000
E23 Hypofunction and other disorders of pituitary gland
0.777 0.223 0.000
M25.56 Pain in joint (Lower leg)
0.777 0.223 0.000
T23 Burn and corrosion of wrist and hand
0.777 0.223 0.000
Z90.1 Acquired absence of breast(s)
0.776 0.224 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.776 0.224 0.000
M23.3 Other meniscus derangements
0.776 0.224 0.000
K50-K52 Noninfective enteritis and colitis
0.775 0.225 0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)
0.775 0.225 0.000
Z89.2 Acquired absence of upper limb above wrist
0.774 0.226 0.000
C51-C58 Malignant neoplasms of female genital organs
0.771 0.229 0.000
T21 Burn and corrosion of trunk
0.769 0.231 0.000
C50.4 Upper-outer quadrant of breast
0.769 0.231 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.769 0.231 0.000
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.768 0.232 0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)
0.767 0.233 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.767 0.233 0.000
F42 Obsessive-compulsive disorder
0.766 0.234 0.000
Z93.9 Artificial opening status, unspecified
0.765 0.234 0.000
G44 Other headache syndromes
0.764 0.236 0.000
M19.03 Primary arthrosis of other joints (Forearm)
0.764 0.236 0.000
E40-E46 Malnutrition
0.764 0.236 0.000
M77.4 Metatarsalgia
0.764 0.236 0.000
Z96.4 Presence of endocrine implants
0.763 0.237 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.763 0.237 0.000
M06.0 Seronegative rheumatoid arthritis
0.763 0.237 0.000
E11.2 With renal complications
0.762 0.238 0.000
M80.0 Postmenopausal osteoporosis with pathological fracture
0.762 0.238 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.762 0.238 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.762 0.238 0.000
M41.96 Scoliosis, unspecified (Lumbar region)
0.761 0.239 0.000
M46.4 Discitis, unspecified
0.761 0.239 0.000
M60-M63 Disorders of muscles
0.760 0.240 0.000
G58.8 Other specified mononeuropathies
0.760 0.240 0.000
M07.3 Other psoriatic arthropathies
0.760 0.240 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.759 0.241 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.759 0.241 0.000
K42 Umbilical hernia
0.759 0.241 0.000
Z89.6 Acquired absence of leg above knee
0.759 0.241 0.000
H66.3 Other chronic suppurative otitis media
0.758 0.242 0.000
D00-D09 In situ neoplasms
0.758 0.242 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.757 0.243 0.000
M25.71 Osteophyte (Shoulder region)
0.757 0.243 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.756 0.243 0.000
T79-T79 Certain early complications of trauma
0.756 0.244 0.000
S62.5 Fracture of thumb
0.756 0.244 0.000
M14 Arthropathies in other diseases classified elsewhere
0.755 0.245 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.755 0.245 0.000
M50.0 Cervical disk disorder with myelopathy
0.754 0.246 0.000
M77.91 Enthesopathy, unspecified (Shoulder region)
0.753 0.247 0.000
S60 Superficial injury of wrist and hand
0.752 0.248 0.000
K21.0 Gastro-oesophageal reflux disease with oesophagitis
0.752 0.248 0.000
M19.90 Arthrosis, unspecified (Multiple sites)
0.751 0.248 0.000
F43 Reaction to severe stress, and adjustment disorders
0.750 0.250 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.750 0.250 0.000
M54.22 Cervicalgia (Cervical region)
0.750 0.250 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.749 0.250 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.749 0.251 0.000
G52 Disorders of other cranial nerves
0.749 0.251 0.000
M89.8 Other specified disorders of bone
0.749 0.251 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.748 0.251 0.000
S67 Crushing injury of wrist and hand
0.748 0.252 0.000
T95 Sequelae of burns, corrosions and frostbite
0.748 0.252 0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.748 0.252 0.000
K22.9 Disease of oesophagus, unspecified
0.748 0.252 0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)
0.747 0.253 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.747 0.253 0.000
F81 Specific developmental disorders of scholastic skills
0.747 0.253 0.000
T91.1 Sequelae of fracture of spine
0.746 0.254 0.000
S20-S29 Injuries to the thorax
0.745 0.255 0.000
M19.04 Primary arthrosis of other joints (Hand)
0.744 0.256 0.000
M25.72 Osteophyte (Upper arm)
0.743 0.257 0.000
G43.9 Migraine, unspecified
0.743 0.257 0.000
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified
0.743 0.257 0.000
G82.4 Spastic tetraplegia
0.742 0.257 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.742 0.258 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.742 0.258 0.000
Z93.8 Other artificial opening status
0.741 0.259 0.000
E11.8 With unspecified complications
0.741 0.259 0.000
M13.93 Arthritis, unspecified (Forearm)
0.741 0.259 0.000
Y10-Y34 Event of undetermined intent
0.740 0.260 0.000
T90 Sequelae of injuries of head
0.740 0.260 0.000
M40.29 Other and unspecified kyphosis (Site unspecified)
0.739 0.261 0.000
M19.2 Other secondary arthrosis
0.739 0.261 0.000
C50.0 Nipple and areola
0.739 0.261 0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)
0.738 0.262 0.000
G54 Nerve root and plexus disorders
0.738 0.262 0.000
M53 Other dorsopathies, not elsewhere classified
0.738 0.262 0.000
M88 Paget's disease of bone [osteitis deformans]
0.737 0.263 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.736 0.264 0.000
M54.55 Low back pain (Thoracolumbar region)
0.736 0.264 0.000
M47.9 Spondylosis, unspecified
0.735 0.265 0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)
0.735 0.265 0.000
V20-V29 Motorcycle rider injured in transport accident
0.735 0.265 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.735 0.265 0.000
E11.5 With peripheral circulatory complications
0.734 0.266 0.000
K82 Other diseases of gallbladder
0.733 0.267 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.733 0.267 0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)
0.732 0.268 0.000
M86 Osteomyelitis
0.732 0.268 0.000
G35 Multiple sclerosis
0.732 0.268 0.000
M77.97 Enthesopathy, unspecified (Ankle and foot)
0.732 0.268 0.000
S10.9 Superficial injury of neck, part unspecified
0.731 0.269 0.000
M25.0 Haemarthrosis
0.731 0.269 0.000
Z89.0 Acquired absence of finger(s) [including thumb], unilateral
0.729 0.270 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.729 0.271 0.000
T43.6 Psychostimulants with abuse potential
0.729 0.271 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.727 0.273 0.000
S62.8 Fracture of other and unspecified parts of wrist and hand
0.727 0.273 0.000
M25.45 Effusion of joint (Pelvic region and thigh)
0.726 0.274 0.000
M25.84 Other specified joint disorders (Hand)
0.726 0.274 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.726 0.274 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.726 0.274 0.000
T43.2 Other and unspecified antidepressants
0.724 0.276 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.724 0.276 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.724 0.276 0.000
C56 Malignant neoplasm of ovary
0.724 0.276 0.000
E29.1 Testicular hypofunction
0.724 0.276 0.000
G58.9 Mononeuropathy, unspecified
0.723 0.277 0.000
M22.2 Patellofemoral disorders
0.723 0.277 0.000
E13 Other specified diabetes mellitus
0.723 0.277 0.000
Z89.5 Acquired absence of leg at or below knee
0.723 0.277 0.000
M87.96 Osteonecrosis, unspecified (Lower leg)
0.722 0.278 0.000
S64.3 Injury of digital nerve of thumb
0.721 0.279 0.000
E34 Other endocrine disorders
0.720 0.280 0.000
T36 Poisoning by systemic antibiotics
0.720 0.280 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.720 0.280 0.000
H66.9 Otitis media, unspecified
0.720 0.280 0.000
M34 Systemic sclerosis
0.719 0.281 0.000
K45 Other abdominal hernia
0.718 0.282 0.000
Z63 Other problems related to primary support group, including family circumstances
0.718 0.282 0.000
S69 Other and unspecified injuries of wrist and hand
0.718 0.282 0.000
M76 Enthesopathies of lower limb, excluding foot
0.718 0.282 0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)
0.717 0.283 0.000
H74.4 Polyp of middle ear
0.717 0.283 0.000
M75.8 Other shoulder lesions
0.717 0.283 0.000
M30 Polyarteritis nodosa and related conditions
0.717 0.283 0.000
M32 Systemic lupus erythematosus
0.717 0.283 0.000
M33 Dermatopolymyositis
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral
0.717 0.283 0.000
M16.4 Posttraumatic coxarthrosis, bilateral
0.717 0.283 0.000
M16.6 Other secondary coxarthrosis, bilateral
0.717 0.283 0.000
M19.8 Other specified arthrosis
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.717 0.283 0.000
F70-F79 Mental retardation
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
Z91.2 Personal history of poor personal hygiene
0.717 0.283 0.000
Z91.3 Personal history of unhealthy sleep-wake schedule
0.717 0.283 0.000
Z91.4 Personal history of psychological trauma, not elsewhere classified
0.717 0.283 0.000
Z91.7 Personal history of female genital mutilation
0.717 0.283 0.000
M08 Juvenile arthritis
0.717 0.283 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.717 0.283 0.000
M12 Other specific arthropathies
0.717 0.283 0.000
S65 Injury of blood vessels at wrist and hand level
0.716 0.283 0.000
M13.1 Monoarthritis, not elsewhere classified
0.716 0.284 0.000
M13.8 Other specified arthritis
0.716 0.284 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.716 0.284 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.716 0.284 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.716 0.284 0.000
M25.1 Fistula of joint
0.716 0.284 0.000
M25.2 Flail joint
0.716 0.284 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.716 0.284 0.000
K28 Gastrojejunal ulcer
0.716 0.284 0.000
E11.7 With multiple complications
0.716 0.284 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.716 0.284 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.716 0.284 0.000
K82.8 Other specified diseases of gallbladder
0.716 0.284 0.000
M40.25 Other and unspecified kyphosis (Thoracolumbar region)
0.716 0.284 0.000
E12 Malnutrition-related diabetes mellitus
0.715 0.284 0.000
S90 Superficial injury of ankle and foot
0.716 0.284 0.000
Z96.3 Presence of artificial larynx
0.715 0.285 0.000
Z96.5 Presence of tooth-root and mandibular implants
0.715 0.285 0.000
K22.3 Perforation of oesophagus
0.714 0.285 0.000
V01-V09 Pedestrian injured in transport accident
0.714 0.286 0.000
S63.6 Sprain and strain of finger(s)
0.714 0.286 0.000
M49.5 Collapsed vertebra in diseases classified elsewhere
0.714 0.286 0.000
G51 Facial nerve disorders
0.713 0.287 0.000
F61 Mixed and other personality disorders
0.713 0.287 0.000
F62 Enduring personality changes, not attributable to brain damage and disease
0.713 0.287 0.000
F63 Habit and impulse disorders
0.713 0.287 0.000
F64 Gender identity disorders
0.713 0.287 0.000
F65 Disorders of sexual preference
0.713 0.287 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.713 0.287 0.000
F68 Other disorders of adult personality and behaviour
0.713 0.287 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.712 0.287 0.000
K44.1 Diaphragmatic hernia with gangrene
0.712 0.288 0.000
M25.3 Other instability of joint
0.712 0.288 0.000
S11 Open wound of neck
0.711 0.289 0.000
G95.2 Cord compression, unspecified
0.711 0.289 0.000
T91.3 Sequelae of injury of spinal cord
0.710 0.289 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.710 0.290 0.000
K42.0 Umbilical hernia with obstruction, without gangrene
0.710 0.290 0.000
G47.2 Disorders of the sleep-wake schedule
0.709 0.291 0.000
G47.4 Narcolepsy and cataplexy
0.709 0.291 0.000
M81.9 Osteoporosis, unspecified
0.709 0.291 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.709 0.291 0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)
0.708 0.292 0.000
F60.0 Paranoid personality disorder
0.708 0.292 0.000
F60.1 Schizoid personality disorder
0.708 0.292 0.000
F60.2 Dissocial personality disorder
0.708 0.292 0.000
F60.4 Histrionic personality disorder
0.708 0.292 0.000
F60.5 Anankastic personality disorder
0.708 0.292 0.000
F60.6 Anxious [avoidant] personality disorder
0.708 0.292 0.000
F60.7 Dependent personality disorder
0.708 0.292 0.000
F60.8 Other specific personality disorders
0.708 0.292 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.708 0.292 0.000
M25.70 Osteophyte (Multiple sites)
0.708 0.292 0.000
M25.73 Osteophyte (Forearm)
0.708 0.292 0.000
M25.79 Osteophyte (Site unspecified)
0.708 0.292 0.000
Y00-Y09 Assault
0.707 0.292 0.000
X10-X19 Contact with heat and hot substances
0.707 0.293 0.000
M22.9 Disorder of patella, unspecified
0.707 0.293 0.000
M22.1 Recurrent subluxation of patella
0.707 0.293 0.000
T00-T07 Injuries involving multiple body regions
0.706 0.294 0.000
M50.9 Cervical disk disorder, unspecified
0.706 0.294 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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