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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2395166
log Bayes Factor = 291.927
Chromosome 6   position 32,388,275  (GRCh37) Explore rs2395166 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
J33.9 Nasal polyp, unspecified
0.000 0.000 1.000
J33.0 Polyp of nasal cavity
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K51.9 Ulcerative colitis, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
M35.3 Polymyalgia rheumatica
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
J33 Nasal polyp
0.000 0.000 1.000
K51 Ulcerative colitis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
D50.9 Iron deficiency anaemia, unspecified
0.000 0.000 1.000
E10.4 With neurological complications
0.000 0.000 1.000
E14.9 Without complications
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.000 1.000
D50 Iron deficiency anaemia
0.000 0.000 1.000
H30-H36 Disorders of choroid and retina
0.000 0.000 1.000
D50-D53 Nutritional anaemias
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
H36 Retinal disorders in diseases classified elsewhere
0.000 0.000 1.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
Chapter VII Diseases of the eye and adnexa
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
D64.9 Anaemia, unspecified
0.000 0.000 1.000
E14.3 With ophthalmic complications
0.000 0.001 0.999
D64 Other anaemias
0.000 0.001 0.999
M35 Other systemic involvement of connective tissue
0.000 0.001 0.999
D60-D64 Aplastic and other anaemias
0.000 0.001 0.999
E11.9 Without complications
0.000 0.002 0.998
E11.3 With ophthalmic complications
0.000 0.002 0.998
E10.5 With peripheral circulatory complications
0.000 0.003 0.997
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.003 0.997
M20-M25 Other joint disorders
0.000 0.005 0.995
J33.8 Other polyp of sinus
0.000 0.005 0.995
Chapter X Diseases of the respiratory system
0.000 0.005 0.995
K90 Intestinal malabsorption
0.000 0.006 0.994
J45 Asthma
0.000 0.006 0.994
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.007 0.993
J40-J47 Chronic lower respiratory diseases
0.000 0.008 0.992
K51.3 Ulcerative (chronic) rectosigmoiditis
0.992 0.008 0.000
K51.2 Ulcerative (chronic) proctitis
0.992 0.008 0.000
D80-D89 Certain disorders involving the immune mechanism
0.000 0.009 0.991
D86 Sarcoidosis
0.000 0.010 0.990
E11.1 With ketoacidosis
0.000 0.012 0.988
E10.2 With renal complications
0.000 0.013 0.987
E06 Thyroiditis
0.000 0.014 0.986
K51.8 Other ulcerative colitis
0.986 0.014 0.000
H35 Other retinal disorders
0.000 0.016 0.984
Chapter XI Diseases of the digestive system
0.000 0.017 0.983
K90-K93 Other diseases of the digestive system
0.000 0.017 0.983
D86.9 Sarcoidosis, unspecified
0.000 0.019 0.981
K70-K77 Diseases of liver
0.000 0.019 0.981
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.021 0.979
E06.3 Autoimmune thyroiditis
0.000 0.023 0.977
H35.8 Other specified retinal disorders
0.000 0.023 0.977
J30-J39 Other diseases of upper respiratory tract
0.000 0.025 0.975
K75 Other inflammatory liver diseases
0.000 0.025 0.975
K75.4 Autoimmune hepatitis
0.000 0.025 0.975
K51.4 Pseudopolyposis of colon
0.975 0.025 0.000
E10.8 With unspecified complications
0.000 0.029 0.971
E10.0 With coma
0.000 0.032 0.968
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.034 0.966
Chapter VIII Diseases of the ear and mastoid process
0.000 0.038 0.962
H60-H62 Diseases of external ear
0.000 0.039 0.961
H61 Other disorders of external ear
0.000 0.042 0.958
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.042 0.958
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.000 0.043 0.957
G35-G37 Demyelinating diseases of the central nervous system
0.953 0.047 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.049 0.951
H61.0 Perichondritis of external ear
0.000 0.049 0.951
D50.8 Other iron deficiency anaemias
0.000 0.052 0.948
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.948 0.052 0.000
K74 Fibrosis and cirrhosis of liver
0.000 0.056 0.944
G37 Other demyelinating diseases of central nervous system
0.942 0.058 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.936 0.064 0.000
E07 Other disorders of thyroid
0.000 0.070 0.930
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.000 0.070 0.930
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.071 0.929
H34 Retinal vascular occlusions
0.000 0.071 0.929
H35.4 Peripheral retinal degeneration
0.000 0.071 0.929
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.078 0.922
H53-H54 Visual disturbances and blindness
0.000 0.082 0.918
M06.4 Inflammatory polyarthropathy
0.000 0.084 0.916
K90.9 Intestinal malabsorption, unspecified
0.000 0.084 0.916
K74.3 Primary biliary cirrhosis
0.000 0.089 0.911
H06.2 Dysthyroid exophthalmos
0.000 0.090 0.910
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.090 0.910
M35.1 Other overlap syndromes
0.000 0.101 0.899
J86 Pyothorax
0.000 0.108 0.892
K73 Chronic hepatitis, not elsewhere classified
0.000 0.108 0.892
H43-H45 Disorders of vitreous body and globe
0.000 0.110 0.890
H54 Blindness and low vision
0.000 0.111 0.889
E14.1 With ketoacidosis
0.000 0.113 0.887
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.114 0.886
E11.5 With peripheral circulatory complications
0.000 0.115 0.885
M23 Internal derangement of knee
0.000 0.115 0.885
M23.3 Other meniscus derangements
0.000 0.117 0.883
H04 Disorders of lachrymal system
0.000 0.122 0.878
E11.2 With renal complications
0.000 0.130 0.870
D86.8 Sarcoidosis of other and combined sites
0.000 0.136 0.864
J46 Status asthmaticus
0.000 0.136 0.864
H43 Disorders of vitreous body
0.000 0.139 0.861
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.000 0.139 0.861
K74.5 Biliary cirrhosis, unspecified
0.000 0.141 0.859
H34.8 Other retinal vascular occlusions
0.000 0.141 0.859
E07.9 Disorder of thyroid, unspecified
0.000 0.145 0.855
K51.5 Mucosal proctocolitis
0.855 0.145 0.000
H61.3 Acquired stenosis of external ear canal
0.000 0.146 0.854
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.146 0.854
D86.1 Sarcoidosis of lymph nodes
0.000 0.146 0.854
E20-E35 Disorders of other endocrine glands
0.000 0.147 0.853
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.156 0.844
E14.8 With unspecified complications
0.000 0.158 0.842
D51 Vitamin B12 deficiency anaemia
0.000 0.158 0.842
E14.6 With other specified complications
0.000 0.159 0.840
H54.7 Unspecified visual loss
0.000 0.160 0.840
E27 Other disorders of adrenal gland
0.000 0.163 0.837
J44 Other chronic obstructive pulmonary disease
0.000 0.165 0.835
E27.1 Primary adrenocortical insufficiency
0.000 0.168 0.832
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.830 0.170 0.000
H61.8 Other specified disorders of external ear
0.000 0.171 0.829
K86 Other diseases of pancreas
0.000 0.171 0.829
M35.7 Hypermobility syndrome
0.000 0.173 0.827
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.174 0.826
H00 Hordeolum and chalazion
0.000 0.175 0.825
E10.6 With other specified complications
0.000 0.175 0.825
D86.3 Sarcoidosis of skin
0.000 0.176 0.823
J33.1 Polypoid sinus degeneration
0.000 0.177 0.823
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.182 0.818
K86.0 Alcohol-induced chronic pancreatitis
0.000 0.183 0.817
H60 Otitis externa
0.000 0.188 0.812
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.191 0.809
J85 Abscess of lung and mediastinum
0.000 0.193 0.807
E03.8 Other specified hypothyroidism
0.000 0.194 0.806
M12 Other specific arthropathies
0.000 0.194 0.806
H54.0 Blindness, both eyes
0.000 0.200 0.800
H00.0 Hordeolum and other deep inflammation of eyelid
0.000 0.202 0.798
H35.2 Other proliferative retinopathy
0.000 0.204 0.796
J86.0 Pyothorax with fistula
0.000 0.206 0.794
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.212 0.788
M34 Systemic sclerosis
0.000 0.213 0.787
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.213 0.787
C82.0 Small cleaved cell, follicular
0.787 0.213 0.000
J84 Other interstitial pulmonary diseases
0.000 0.215 0.785
J86.9 Pyothorax without fistula
0.000 0.215 0.785
H35.6 Retinal haemorrhage
0.000 0.216 0.784
E11.6 With other specified complications
0.000 0.217 0.783
H04.5 Stenosis and insufficiency of lachrymal passages
0.000 0.218 0.782
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.219 0.781
J84.9 Interstitial pulmonary disease, unspecified
0.000 0.219 0.781
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.000 0.222 0.778
M31 Other necrotising vasculopathies
0.000 0.225 0.775
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.228 0.772
M86-M90 Other osteopathies
0.000 0.231 0.769
M23.30 Other meniscus derangements (Multiple sites)
0.000 0.235 0.765
M32 Systemic lupus erythematosus
0.000 0.236 0.763
H43.8 Other disorders of vitreous body
0.000 0.242 0.758
E14.2 Withrenal complications
0.000 0.242 0.758
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.243 0.757
M35.2 Behcet's disease
0.000 0.244 0.756
E07.8 Other specified disorders of thyroid
0.000 0.246 0.754
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.246 0.754
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.247 0.753
M05.2 Rheumatoid vasculitis
0.000 0.249 0.751
D50.1 Sideropenic dysphagia
0.000 0.253 0.747
D83 Common variable immunodeficiency
0.000 0.258 0.742
D86.0 Sarcoidosis of lung
0.000 0.259 0.741
H43.1 Vitreous haemorrhage
0.000 0.260 0.740
H04.9 Disorder of lachrymal system, unspecified
0.000 0.265 0.735
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.000 0.266 0.734
H04.3 Acute and unspecified inflammation of lachrymal passages
0.000 0.267 0.733
J95-J99 Other diseases of the respiratory system
0.000 0.267 0.733
J85.2 Abscess of lung without pneumonia
0.000 0.270 0.730
K71 Toxic liver disease
0.000 0.271 0.729
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.272 0.728
M06.3 Rheumatoid nodule
0.000 0.273 0.727
H04.8 Other disorders of lachrymal system
0.000 0.274 0.726
M23.0 Cystic meniscus
0.000 0.274 0.726
E16.1 Other hypoglycaemia
0.000 0.276 0.724
H04.4 Chronic inflammation of lachrymal passages
0.000 0.276 0.724
E11.8 With unspecified complications
0.000 0.276 0.724
H61.1 Non-infective disorders of pinna
0.000 0.276 0.724
K72 Hepatic failure, not elsewhere classified
0.000 0.280 0.720
D53 Other nutritional anaemias
0.000 0.281 0.718
M31.6 Other giant cell arteritis
0.000 0.282 0.718
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.282 0.718
H34.2 Other retinal artery occlusions
0.000 0.282 0.718
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.283 0.717
H43.3 Other vitreous opacities
0.000 0.283 0.717
K86.1 Other chronic pancreatitis
0.000 0.284 0.716
D64.4 Congenital dyserythropoietic anaemia
0.000 0.284 0.716
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.284 0.716
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.284 0.716
M10 Gout
0.000 0.284 0.716
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.284 0.716
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.284 0.716
M35.5 Multifocal fibrosclerosis
0.000 0.284 0.716
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.284 0.716
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.284 0.716
K90.3 Pancreatic steatorrhoea
0.000 0.287 0.713
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.287 0.713
K90.1 Tropical sprue
0.000 0.287 0.713
K73.9 Chronic hepatitis, unspecified
0.000 0.287 0.713
E14.5 With peripheral circulatory complications
0.000 0.288 0.712
H62 Disorders of external ear in diseases classified elsewhere
0.000 0.288 0.712
M23.5 Chronic instability of knee
0.000 0.289 0.711
D81 Combined immunodeficiencies
0.000 0.289 0.711
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.000 0.291 0.709
E06.5 Other chronic thyroiditis
0.000 0.293 0.707
E06.4 Drug-induced thyroiditis
0.000 0.293 0.707
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.293 0.707
E06.1 Subacute thyroiditis
0.000 0.293 0.707
E06.0 Acute thyroiditis
0.000 0.293 0.707
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.293 0.707
M06.8 Other specified rheumatoid arthritis
0.000 0.294 0.706
G36 Other acute disseminated demyelination
0.705 0.295 0.000
H35.1 Retinopathy of prematurity
0.000 0.295 0.705
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.295 0.705
K77 Liver disorders in diseases classified elsewhere
0.000 0.297 0.703
D82 Immunodeficiency associated with other major defects
0.000 0.298 0.702
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.299 0.701
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.299 0.701
K75.2 Nonspecific reactive hepatitis
0.000 0.301 0.699
K75.1 Phlebitis of portal vein
0.000 0.301 0.699
E05.8 Other thyrotoxicosis
0.000 0.301 0.699
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.000 0.302 0.698
D64.8 Other specified anaemias
0.000 0.302 0.698
J37 Chronic laryngitis and laryngotracheitis
0.000 0.302 0.698
H54.1 Blindness, one eye, low vision, other eye
0.000 0.306 0.694
M86 Osteomyelitis
0.000 0.306 0.694
H60.3 Other infective otitis externa
0.000 0.307 0.693
M22 Disorders of patella
0.000 0.307 0.693
H54.9 Unspecified visual impairment (binocular)
0.000 0.308 0.692
E24 Cushing's syndrome
0.000 0.308 0.692
M12.3 Palindromic rheumatism
0.000 0.311 0.689
M35.0 Sicca syndrome [Sjogren]
0.000 0.312 0.688
E06.9 Thyroiditis, unspecified
0.000 0.313 0.687
C82.1 Mixed small cleaved and large cell, follicular
0.686 0.313 0.000
H34.9 Retinal vascular occlusion, unspecified
0.000 0.314 0.686
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.315 0.685
E13 Other specified diabetes mellitus
0.000 0.317 0.683
G37.8 Other specified demyelinating diseases of central nervous system
0.683 0.317 0.000
H01 Other inflammation of eyelid
0.000 0.318 0.682
H54.2 Low vision, both eyes
0.000 0.318 0.682
C82.3 Follicular lymphoma grade IIIa
0.681 0.319 0.000
E29 Testicular dysfunction
0.000 0.320 0.680
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.321 0.679
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.321 0.679
H34.1 Central retinal artery occlusion
0.000 0.322 0.678
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.322 0.678
K74.4 Secondary biliary cirrhosis
0.000 0.323 0.677
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.323 0.677
G37.5 Concentric sclerosis [Balo]
0.676 0.324 0.000
G37.4 Subacute necrotising myelitis
0.676 0.324 0.000
G37.2 Central pontine myelinolysis
0.676 0.324 0.000
G37.1 Central demyelination of corpus callosum
0.676 0.324 0.000
G37.0 Diffuse sclerosis
0.676 0.324 0.000
M14 Arthropathies in other diseases classified elsewhere
0.000 0.326 0.673
M33 Dermatopolymyositis
0.000 0.329 0.671
D52 Folate deficiency anaemia
0.000 0.331 0.669
E07.1 Dyshormogenetic goitre
0.000 0.333 0.667
E07.0 Hypersecretion of calcitonin
0.000 0.333 0.667
H06.3 Other disorders of orbit in diseases classified elsewhere
0.000 0.333 0.667
H06.1 Parasitic infestation of orbit in diseases classified elsewhere
0.000 0.333 0.667
H06.0 Disorders of lachrymal system in diseases classified elsewhere
0.000 0.333 0.667
H34.0 Transient retinal artery occlusion
0.000 0.334 0.666
H43.9 Disorder of vitreous body, unspecified
0.000 0.335 0.665
D64.0 Hereditary sideroblastic anaemia
0.000 0.338 0.662
D64.3 Other sideroblastic anaemias
0.000 0.339 0.661
E14.4 With neurological complications
0.000 0.339 0.661
H60.9 Otitis externa, unspecified
0.000 0.339 0.661
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.000 0.343 0.657
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.343 0.657
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.343 0.657
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.343 0.657
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.343 0.657
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.343 0.657
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.343 0.657
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.343 0.657
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.343 0.657
H54.5 Low vision, one eye
0.000 0.343 0.657
H43.2 Crystalline deposits in vitreous body
0.000 0.344 0.656
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.344 0.656
J31.2 Chronic pharyngitis
0.000 0.346 0.654
H60.8 Other otitis externa
0.000 0.346 0.654
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.000 0.346 0.654
M34.1 CR(E)ST syndrome
0.000 0.348 0.652
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.000 0.349 0.651
K86.3 Pseudocyst of pancreas
0.000 0.349 0.650
K90.8 Other intestinal malabsorption
0.000 0.351 0.649
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.000 0.353 0.647
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.353 0.647
E40-E46 Malnutrition
0.000 0.354 0.646
H35.5 Hereditary retinal dystrophy
0.000 0.355 0.645
Chapter IX Diseases of the circulatory system
0.000 0.356 0.644
H35.0 Background retinopathy and retinal vascular changes
0.000 0.359 0.641
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.360 0.640
K86.9 Disease of pancreas, unspecified
0.000 0.360 0.640
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.361 0.639
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.361 0.639
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.362 0.638
H54.3 Unqualified visual loss, both eyes
0.000 0.362 0.638
H61.9 Disorder of external ear, unspecified
0.000 0.362 0.638
M86.9 Osteomyelitis, unspecified
0.000 0.364 0.636
M22.2 Patellofemoral disorders
0.000 0.366 0.634
M23.37 Other meniscus derangements-Capsular lig
0.000 0.367 0.633
H60.2 Malignant otitis externa
0.000 0.368 0.632
J41 Simple and mucopurulent chronic bronchitis
0.000 0.368 0.632
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.369 0.631
H04.0 Dacryoadenitis
0.000 0.370 0.629
M60-M63 Disorders of muscles
0.000 0.371 0.628
E31 Polyglandular dysfunction
0.000 0.372 0.628
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.627 0.372 0.000
E03.1 Congenital hypothyroidism without goitre
0.000 0.373 0.627
I70 Atherosclerosis
0.000 0.375 0.625
E20 Hypoparathyroidism
0.000 0.375 0.625
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.375 0.624
K72.0 Acute and subacute hepatic failure
0.000 0.377 0.623
J85.0 Gangrene and necrosis of lung
0.000 0.379 0.621
I77 Other disorders of arteries and arterioles
0.000 0.381 0.619
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.382 0.618
H43.0 Vitreous prolapse
0.000 0.382 0.618
C82.2 Large cell, follicular
0.617 0.383 0.000
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)
0.000 0.384 0.616
H54.6 Unqualified visual loss, one eye
0.000 0.384 0.616
H30 Chorioretinal inflammation
0.000 0.385 0.615
J45.1 Nonallergic asthma
0.000 0.386 0.613
D61 Other aplastic anaemias
0.000 0.386 0.614
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.000 0.387 0.613
J42 Unspecified chronic bronchitis
0.000 0.388 0.612
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.388 0.612
E32 Diseases of thymus
0.000 0.388 0.612
E30 Disorders of puberty, not elsewhere classified
0.000 0.388 0.612
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.389 0.611
I77.1 Stricture of artery
0.000 0.389 0.611
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.390 0.610
E28 Ovarian dysfunction
0.000 0.390 0.610
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.393 0.606
H04.6 Other changes in lachrymal passages
0.000 0.395 0.605
K74.0 Hepatic fibrosis
0.000 0.395 0.605
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.000 0.395 0.605
I10-I15 Hypertensive diseases
0.000 0.395 0.605
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.396 0.604
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.396 0.604
D51.2 Transcobalamin II deficiency
0.000 0.396 0.604
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.396 0.604
K51.1 Ulcerative (chronic) ileocolitis
0.603 0.397 0.000
K50-K52 Noninfective enteritis and colitis
0.511 0.398 0.091
K74.6 Other and unspecified cirrhosis of liver
0.000 0.398 0.602
E27.5 Adrenomedullary hyperfunction
0.000 0.400 0.600
E27.0 Other adrenocortical overactivity
0.000 0.400 0.600
M06.34 Rheumatoid nodule (Hand)
0.000 0.400 0.600
C82.6 Cutaneous follicle centre lymphoma
0.595 0.405 0.000
C82.5 Diffuse follicle centre lymphoma
0.595 0.405 0.000
I70.0 Atherosclerosis of aorta
0.000 0.405 0.595
M10.9 Gout, unspecified
0.000 0.405 0.595
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.000 0.405 0.595
M30 Polyarteritis nodosa and related conditions
0.000 0.410 0.590
K82 Other diseases of gallbladder
0.000 0.411 0.589
M32.1 Systemic lupus erythematosus with organ or system involvement
0.000 0.413 0.587
J45.8 Mixed asthma
0.000 0.413 0.587
M12.39 Palindromic rheumatism (Site unspecified)
0.000 0.414 0.586
E29.1 Testicular hypofunction
0.000 0.414 0.586
K75.9 Inflammatory liver disease, unspecified
0.000 0.414 0.586
H01.8 Other specified inflammation of eyelid
0.000 0.415 0.584
M91-M94 Chondropathies
0.000 0.416 0.584
M23.4 Loose body in knee
0.000 0.416 0.584
M89 Other disorders of bone
0.000 0.416 0.584
J45.0 Predominantly allergic asthma
0.000 0.417 0.583
K83 Other diseases of biliary tract
0.000 0.420 0.580
M12.5 Traumatic arthropathy
0.000 0.420 0.579
J85.3 Abscess of mediastinum
0.000 0.421 0.579
I73 Other peripheral vascular diseases
0.000 0.422 0.578
M12.8 Other specific arthropathies, not elsewhere classified
0.000 0.422 0.578
M12.4 Intermittent hydrarthrosis
0.000 0.422 0.578
M12.1 Kaschin-Beck disease
0.000 0.422 0.578
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.000 0.422 0.578
M34.0 Progressive systemic sclerosis
0.000 0.423 0.577
M35.8 Other specified systemic involvement of connective tissue
0.000 0.424 0.576
J95.0 Tracheostomy malfunction
0.000 0.424 0.576
M34.9 Systemic sclerosis, unspecified
0.000 0.426 0.574
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.426 0.574
M05.29 Rheumatoid vasculitis (Site unspecified)
0.000 0.428 0.572
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.428 0.572
M23.09 Cystic meniscus (Unspecified ligament or Unspecified meniscus)
0.000 0.429 0.571
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.431 0.569
H16 Keratitis
0.000 0.432 0.568
J43 Emphysema
0.000 0.432 0.568
M31.8 Other specified necrotising vasculopathies
0.000 0.433 0.567
E24.2 Drug-induced Cushing's syndrome
0.000 0.433 0.567
M23.1 Discoid meniscus (congenital)
0.000 0.433 0.566
M34.2 Systemic sclerosis induced by drugs and chemicals
0.000 0.435 0.564
E11.0 With coma
0.000 0.436 0.563
D83.9 Common variable immunodeficiency, unspecified
0.000 0.436 0.563
J84.0 Alveolar and parietoalveolar conditions
0.000 0.437 0.563
H20 Iridocyclitis
0.000 0.438 0.562
J38.6 Stenosis of larynx
0.000 0.439 0.561
I73.9 Peripheral vascular disease, unspecified
0.000 0.440 0.560
J31.1 Chronic nasopharyngitis
0.000 0.440 0.560
M32.8 Other forms of systemic lupus erythematosus
0.000 0.440 0.560
I12 Hypertensive renal disease
0.000 0.442 0.558
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.442 0.558
M31.7 Microscopic polyangiitis
0.000 0.444 0.556
M31.2 Lethal midline granuloma
0.000 0.444 0.556
E11.4 With neurological complications
0.000 0.444 0.556
M31.4 Aortic arch syndrome [Takayasu]
0.000 0.445 0.555
I71 Aortic aneurysm and dissection
0.000 0.446 0.554
J38.2 Nodules of vocal cords
0.000 0.449 0.551
E26 Hyperaldosteronism
0.000 0.450 0.550
M89.8 Other specified disorders of bone
0.000 0.451 0.549
H61.2 Impacted cerumen
0.000 0.451 0.549
H60.4 Cholesteatoma of external ear
0.000 0.452 0.548
J84.8 Other specified interstitial pulmonary diseases
0.000 0.452 0.548
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.547 0.452 0.000
M32.9 Systemic lupus erythematosus, unspecified
0.000 0.452 0.547
M32.0 Drug-induced systemic lupus erythematosus
0.000 0.452 0.547
K71.0 Toxic liver disease with cholestasis
0.000 0.454 0.546
M90 Osteopathies in diseases classified elsewhere
0.000 0.457 0.543
I12.9 Hypertensive renal disease without renal failure
0.000 0.457 0.543
K71.1 Toxic liver disease with hepatic necrosis
0.000 0.457 0.542
D89.9 Disorder involving the immune mechanism, unspecified
0.000 0.458 0.542
K51.0 Ulcerative (chronic) enterocolitis
0.542 0.458 0.000
H35.7 Separation of retinal layers
0.000 0.458 0.541
M22.9 Disorder of patella, unspecified
0.000 0.459 0.541
M00-M03 Infectious arthropathies
0.000 0.460 0.540
M05.28 Rheumatoid vasculitis (Other)
0.000 0.462 0.538
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.000 0.462 0.538
M05.26 Rheumatoid vasculitis (Lower leg)
0.000 0.462 0.538
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)
0.000 0.462 0.538
M05.24 Rheumatoid vasculitis (Hand)
0.000 0.462 0.538
M05.23 Rheumatoid vasculitis (Forearm)
0.000 0.462 0.538
M05.22 Rheumatoid vasculitis (Upper arm)
0.000 0.462 0.538
M05.21 Rheumatoid vasculitis (Shoulder region)
0.000 0.462 0.538
M05.20 Rheumatoid vasculitis (Multiple sites)
0.000 0.462 0.538
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.462 0.538
M11 Other crystal arthropathies
0.000 0.463 0.537
E27.8 Other specified disorders of adrenal gland
0.000 0.464 0.536
M21 Other acquired deformities of limbs
0.000 0.464 0.536
K81 Cholecystitis
0.000 0.465 0.535
M86.6 Other chronic osteomyelitis
0.000 0.466 0.534
H62.0 Otitis externa in bacterial diseases classified elsewhere
0.000 0.467 0.533
K82.8 Other specified diseases of gallbladder
0.000 0.467 0.533
D83.8 Other common variable immunodeficiencies
0.000 0.468 0.532
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.000 0.468 0.532

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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