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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3135338
log Bayes Factor = 297.666
Chromosome 6   position 32,401,217  (GRCh37) Explore rs3135338 on Ensembl!
Variant rs3135338 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.4 With neurological complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
J33.9 Nasal polyp, unspecified
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
M35.3 Polymyalgia rheumatica
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
J33 Nasal polyp
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
J40-J47 Chronic lower respiratory diseases
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.000 1.000
J33.0 Polyp of nasal cavity
0.000 0.000 1.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.000 1.000
M35 Other systemic involvement of connective tissue
0.000 0.000 1.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
J45 Asthma
0.000 0.000 1.000
Chapter X Diseases of the respiratory system
0.000 0.000 1.000
J44 Other chronic obstructive pulmonary disease
0.000 0.000 1.000
E14.3 With ophthalmic complications
0.000 0.000 1.000
M20-M25 Other joint disorders
0.000 0.000 1.000
J30-J39 Other diseases of upper respiratory tract
0.000 0.001 0.999
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.001 0.999
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.001 0.999
E14.9 Without complications
0.000 0.001 0.999
M06.0 Seronegative rheumatoid arthritis
0.000 0.003 0.997
E10.5 With peripheral circulatory complications
0.000 0.004 0.996
E10.2 With renal complications
0.000 0.004 0.996
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.005 0.995
# Top node
0.000 0.007 0.993
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.008 0.992
J32 Chronic sinusitis
0.000 0.009 0.991
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.010 0.990
E11.1 With ketoacidosis
0.000 0.010 0.990
E06 Thyroiditis
0.000 0.012 0.988
M34 Systemic sclerosis
0.000 0.013 0.987
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.016 0.984
J33.8 Other polyp of sinus
0.000 0.017 0.983
M06.3 Rheumatoid nodule
0.000 0.017 0.983
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.020 0.980
E11.9 Without complications
0.000 0.021 0.979
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.022 0.978
E06.3 Autoimmune thyroiditis
0.000 0.023 0.977
E11.3 With ophthalmic complications
0.000 0.028 0.972
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.031 0.969
E10.0 With coma
0.000 0.032 0.968
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.044 0.955
J32.0 Chronic maxillary sinusitis
0.000 0.047 0.953
M45-M49 Spondylopathies
0.000 0.048 0.952
M45 Ankylosing spondylitis
0.000 0.048 0.952
E10.8 With unspecified complications
0.000 0.048 0.952
M06.4 Inflammatory polyarthropathy
0.000 0.049 0.951
M34.1 CR(E)ST syndrome
0.000 0.054 0.946
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.055 0.945
G35-G37 Demyelinating diseases of the central nervous system
0.942 0.056 0.002
E11.5 With peripheral circulatory complications
0.000 0.056 0.944
M06.34 Rheumatoid nodule (Hand)
0.000 0.057 0.943
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.062 0.938
E11.4 With neurological complications
0.000 0.063 0.937
L43 Lichen planus
0.000 0.063 0.937
L40-L45 Papulosquamous disorders
0.000 0.065 0.935
L43.9 Lichen planus, unspecified
0.000 0.066 0.934
E07 Other disorders of thyroid
0.000 0.067 0.933
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.067 0.933
G37 Other demyelinating diseases of central nervous system
0.929 0.071 0.001
G37.9 Demyelinating disease of central nervous system, unspecified
0.922 0.078 0.000
M34.9 Systemic sclerosis, unspecified
0.000 0.084 0.916
J32.4 Chronic pansinusitis
0.000 0.085 0.915
J47 Bronchiectasis
0.000 0.087 0.913
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.089 0.911
H36 Retinal disorders in diseases classified elsewhere
0.000 0.095 0.905
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.099 0.901
J46 Status asthmaticus
0.000 0.101 0.899
K90 Intestinal malabsorption
0.000 0.106 0.894
M35.1 Other overlap syndromes
0.000 0.110 0.890
J20-J22 Other acute lower respiratory infections
0.000 0.110 0.889
E14.1 With ketoacidosis
0.000 0.111 0.889
L43.8 Other lichen planus
0.000 0.116 0.884
M30 Polyarteritis nodosa and related conditions
0.000 0.121 0.879
E10.6 With other specified complications
0.000 0.121 0.879
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.123 0.877
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.129 0.871
E14.6 With other specified complications
0.000 0.132 0.868
E07.9 Disorder of thyroid, unspecified
0.000 0.134 0.866
M65-M68 Disorders of synovium and tendon
0.000 0.137 0.863
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.138 0.862
K90-K93 Other diseases of the digestive system
0.000 0.142 0.858
Chapter XI Diseases of the digestive system
0.000 0.143 0.857
K70-K77 Diseases of liver
0.000 0.150 0.850
K75 Other inflammatory liver diseases
0.000 0.151 0.849
K75.4 Autoimmune hepatitis
0.000 0.152 0.848
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.154 0.846
J44.9 Chronic obstructive pulmonary disease, unspecified
0.000 0.157 0.843
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.158 0.842
H30-H36 Disorders of choroid and retina
0.000 0.162 0.838
J22 Unspecified acute lower respiratory infection
0.000 0.167 0.833
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.169 0.831
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.170 0.830
D64.9 Anaemia, unspecified
0.000 0.170 0.830
J32.9 Chronic sinusitis, unspecified
0.000 0.171 0.829
M35.7 Hypermobility syndrome
0.000 0.171 0.829
J32.8 Other chronic sinusitis
0.000 0.173 0.827
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.176 0.824
D64 Other anaemias
0.000 0.179 0.821
Chapter VII Diseases of the eye and adnexa
0.000 0.179 0.821
M35.2 Behcet's disease
0.000 0.180 0.820
D60-D64 Aplastic and other anaemias
0.000 0.181 0.819
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.181 0.819
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.184 0.816
E11.2 With renal complications
0.000 0.187 0.813
M65 Synovitis and tenosynovitis
0.000 0.188 0.812
E11.8 With unspecified complications
0.000 0.192 0.808
M14 Arthropathies in other diseases classified elsewhere
0.000 0.198 0.802
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.199 0.801
E14.8 With unspecified complications
0.000 0.204 0.796
M35.0 Sicca syndrome [Sjogren]
0.000 0.206 0.794
K73 Chronic hepatitis, not elsewhere classified
0.000 0.207 0.793
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.209 0.791
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.212 0.788
L80 Vitiligo
0.000 0.212 0.788
E11.6 With other specified complications
0.000 0.214 0.786
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.220 0.780
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.222 0.778
E14.2 Withrenal complications
0.000 0.223 0.777
L10-L14 Bullous disorders
0.000 0.224 0.776
E03.8 Other specified hypothyroidism
0.000 0.227 0.773
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.227 0.773
J84 Other interstitial pulmonary diseases
0.000 0.228 0.772
J32.2 Chronic ethmoidal sinusitis
0.000 0.236 0.764
J84.9 Interstitial pulmonary disease, unspecified
0.000 0.236 0.764
E06.9 Thyroiditis, unspecified
0.000 0.239 0.761
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.239 0.761
E14.4 With neurological complications
0.000 0.247 0.753
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.251 0.749
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.251 0.749
M30.0 Polyarteritis nodosa
0.000 0.252 0.748
M80-M85 Disorders of bone density and structure
0.000 0.256 0.744
E07.8 Other specified disorders of thyroid
0.000 0.257 0.743
M34.8 Other forms of systemic sclerosis
0.000 0.259 0.741
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.260 0.740
E14.5 With peripheral circulatory complications
0.000 0.264 0.736
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.264 0.736
J86 Pyothorax
0.000 0.269 0.731
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.269 0.731
M60-M63 Disorders of muscles
0.000 0.280 0.720
J37 Chronic laryngitis and laryngotracheitis
0.000 0.281 0.719
M15-M19 Arthrosis
0.000 0.282 0.718
M49 Spondylopathies in diseases classified elsewhere
0.000 0.283 0.717
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
J33.1 Polypoid sinus degeneration
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.283 0.717
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.283 0.717
M35.5 Multifocal fibrosclerosis
0.000 0.283 0.717
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.2 Rheumatoid vasculitis
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
M18 Arthrosis of first carpometacarpal joint
0.000 0.284 0.716
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.285 0.715
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.285 0.715
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.285 0.715
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.285 0.715
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.285 0.715
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.285 0.715
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.000 0.286 0.714
M80 Osteoporosis with pathological fracture
0.000 0.287 0.713
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.288 0.712
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.288 0.712
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.290 0.709
E06.5 Other chronic thyroiditis
0.000 0.292 0.708
E06.4 Drug-induced thyroiditis
0.000 0.292 0.708
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.292 0.708
E06.1 Subacute thyroiditis
0.000 0.292 0.708
E06.0 Acute thyroiditis
0.000 0.292 0.708
M34.2 Systemic sclerosis induced by drugs and chemicals
0.000 0.292 0.707
M34.0 Progressive systemic sclerosis
0.000 0.292 0.707
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.295 0.705
M06.38 Rheumatoid nodule (Other)
0.000 0.295 0.705
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.295 0.705
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.295 0.705
M06.33 Rheumatoid nodule (Forearm)
0.000 0.295 0.705
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.295 0.705
M32 Systemic lupus erythematosus
0.000 0.297 0.703
M80.9 Unspecified osteoporosis with pathological fracture
0.000 0.297 0.703
E16.1 Other hypoglycaemia
0.000 0.298 0.702
M31 Other necrotising vasculopathies
0.000 0.300 0.700
K90.9 Intestinal malabsorption, unspecified
0.000 0.303 0.697
M14.6 Neuropathic arthropathy
0.000 0.305 0.695
M18.1 Other primary arthrosis of first carpometacarpal joint
0.000 0.306 0.694
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.309 0.691
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.000 0.311 0.689
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.312 0.688
J31.2 Chronic pharyngitis
0.000 0.317 0.683
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.318 0.682
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.318 0.682
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.318 0.682
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.318 0.682
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.318 0.682
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.318 0.682
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.318 0.682
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.318 0.682
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.318 0.682
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.318 0.682
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.318 0.682
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.318 0.682
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.318 0.682
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.318 0.682
L95 Vasculitis limited to skin, not elsewhere classified
0.000 0.319 0.681
E13 Other specified diabetes mellitus
0.000 0.319 0.681
K73.9 Chronic hepatitis, unspecified
0.000 0.320 0.680
M80.98 Unspecified osteoporosis with pathological fracture (Other)
0.000 0.322 0.678
J85 Abscess of lung and mediastinum
0.000 0.323 0.677
M12 Other specific arthropathies
0.000 0.323 0.677
M24 Other specific joint derangements
0.000 0.324 0.676
H34 Retinal vascular occlusions
0.000 0.324 0.676
L12 Pemphigoid
0.000 0.327 0.673
M82 Osteoporosis in diseases classified elsewhere
0.000 0.327 0.673
G37.8 Other specified demyelinating diseases of central nervous system
0.672 0.328 0.000
L43.3 Subacute (active) lichen planus
0.000 0.328 0.672
L43.2 Lichenoid drug reaction
0.000 0.328 0.672
L43.1 Bullous lichen planus
0.000 0.328 0.672
L43.0 Hypertrophic lichen planus
0.000 0.328 0.672
K75.9 Inflammatory liver disease, unspecified
0.000 0.328 0.672
L41 Parapsoriasis
0.000 0.330 0.670
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.330 0.670
M91-M94 Chondropathies
0.000 0.331 0.669
E07.1 Dyshormogenetic goitre
0.000 0.331 0.669
E07.0 Hypersecretion of calcitonin
0.000 0.331 0.669
J45.1 Nonallergic asthma
0.000 0.333 0.666
G37.5 Concentric sclerosis [Balo]
0.666 0.334 0.001
G37.4 Subacute necrotising myelitis
0.666 0.334 0.001
G37.2 Central pontine myelinolysis
0.666 0.334 0.001
G37.1 Central demyelination of corpus callosum
0.666 0.334 0.001
G37.0 Diffuse sclerosis
0.666 0.334 0.001
E40-E46 Malnutrition
0.000 0.336 0.664
J41 Simple and mucopurulent chronic bronchitis
0.000 0.337 0.662
M86-M90 Other osteopathies
0.000 0.338 0.662
L94 Other localised connective tissue disorders
0.000 0.339 0.661
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.342 0.658
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.345 0.655
L44 Other papulosquamous disorders
0.000 0.345 0.654
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.347 0.653
M65.9 Synovitis and tenosynovitis, unspecified
0.000 0.350 0.650
M65.1 Other infective (teno)synovitis
0.000 0.350 0.650
J32.1 Chronic frontal sinusitis
0.000 0.351 0.649
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.351 0.649
E05.8 Other thyrotoxicosis
0.000 0.352 0.648
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.354 0.646
J21 Acute bronchiolitis
0.000 0.357 0.642
G36 Other acute disseminated demyelination
0.641 0.358 0.001
K74 Fibrosis and cirrhosis of liver
0.000 0.359 0.641
K90.3 Pancreatic steatorrhoea
0.000 0.359 0.641
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.359 0.641
K90.1 Tropical sprue
0.000 0.359 0.641
K71 Toxic liver disease
0.000 0.364 0.636
K72 Hepatic failure, not elsewhere classified
0.000 0.364 0.636
J82 Pulmonary eosinophilia, not elsewhere classified
0.000 0.366 0.634
M60 Myositis
0.000 0.367 0.633
L57.0 Actinic keratosis
0.000 0.369 0.631
M30.8 Other conditions related to polyarteritis nodosa
0.000 0.370 0.630
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]
0.000 0.370 0.630
M30.2 Juvenile polyarteritis
0.000 0.370 0.630
J60-J70 Lung diseases due to external agents
0.000 0.371 0.629
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)
0.000 0.372 0.628
J45.8 Mixed asthma
0.000 0.372 0.627
E11.0 With coma
0.000 0.373 0.626
D62 Acute posthaemorrhagic anaemia
0.000 0.374 0.626
M07 Psoriatic and enteropathic arthropathies
0.000 0.376 0.624
M82.1 Osteoporosis in endocrine disorders
0.000 0.378 0.622
D63.8 Anaemia in other chronic diseases classified elsewhere
0.000 0.379 0.621
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.381 0.619
M86 Osteomyelitis
0.000 0.382 0.618
J86.0 Pyothorax with fistula
0.000 0.383 0.617
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.385 0.615
L95.8 Other vasculitis limited to skin
0.000 0.385 0.615
M00-M03 Infectious arthropathies
0.000 0.385 0.614
K75.8 Other specified inflammatory liver diseases
0.000 0.389 0.611
K77 Liver disorders in diseases classified elsewhere
0.000 0.391 0.609
K75.2 Nonspecific reactive hepatitis
0.000 0.391 0.608
K75.1 Phlebitis of portal vein
0.000 0.391 0.608
L83 Acanthosis nigricans
0.000 0.393 0.607
J42 Unspecified chronic bronchitis
0.000 0.396 0.604
L13 Other bullous disorders
0.000 0.398 0.602
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.398 0.602
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.399 0.601
H30 Chorioretinal inflammation
0.000 0.400 0.600
E03.1 Congenital hypothyroidism without goitre
0.000 0.402 0.598
K50-K52 Noninfective enteritis and colitis
0.004 0.404 0.592
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.000 0.404 0.596
L87 Transepidermal elimination disorders
0.000 0.404 0.596
L86 Keratoderma in diseases classified elsewhere
0.000 0.404 0.596
J31.1 Chronic nasopharyngitis
0.000 0.406 0.594
M86.9 Osteomyelitis, unspecified
0.000 0.407 0.593
K82 Other diseases of gallbladder
0.000 0.409 0.591
D64.4 Congenital dyserythropoietic anaemia
0.000 0.411 0.589
D64.3 Other sideroblastic anaemias
0.000 0.411 0.589
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.411 0.589
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.411 0.589
D64.0 Hereditary sideroblastic anaemia
0.000 0.411 0.589
L12.1 Cicatricial pemphigoid
0.000 0.412 0.588
M20 Acquired deformities of fingers and toes
0.000 0.412 0.588
M10 Gout
0.000 0.413 0.587
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.413 0.587
L84 Corns and callosities
0.000 0.413 0.587
M20.6 Acquired deformity of toe(s), unspecified
0.000 0.415 0.585
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.000 0.415 0.585
M66 Spontaneous rupture of synovium and tendon
0.000 0.415 0.584
M65.2 Calcific tendinitis
0.000 0.418 0.582
M65.0 Abscess of tendon sheath
0.000 0.418 0.582
K82.8 Other specified diseases of gallbladder
0.000 0.418 0.582
M35.8 Other specified systemic involvement of connective tissue
0.000 0.419 0.580
L42 Pityriasis rosea
0.000 0.421 0.579
M11 Other crystal arthropathies
0.000 0.421 0.579
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.000 0.423 0.577
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.425 0.575
M14.4 Arthropathy in amyloidosis
0.000 0.425 0.575
M14.3 Lipoid dermatoarthritis
0.000 0.425 0.575
M14.2 Diabetic arthropathy
0.000 0.425 0.575
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.425 0.575
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.425 0.575
J85.2 Abscess of lung without pneumonia
0.000 0.425 0.575
H40-H42 Glaucoma
0.000 0.427 0.573
K52 Other non-infective gastro-enteritis and colitis
0.001 0.429 0.570
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)
0.000 0.429 0.571
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.432 0.568
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.432 0.568
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.432 0.568
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec
0.000 0.435 0.565
M65.48 Radial styloid tenosynovitis [de Quervain]-Other
0.000 0.435 0.565
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot
0.000 0.435 0.565
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg
0.000 0.435 0.565
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh
0.000 0.435 0.565
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm
0.000 0.435 0.565
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region
0.000 0.435 0.565
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)
0.000 0.435 0.565
K52.8 Other specified non-infective gastro-enteritis and colitis
0.000 0.435 0.565
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.564 0.435 0.001
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.437 0.562
M24.7 Protrusio acetabuli
0.000 0.437 0.562
K90.8 Other intestinal malabsorption
0.000 0.438 0.562
J86.9 Pyothorax without fistula
0.000 0.438 0.562
H43-H45 Disorders of vitreous body and globe
0.000 0.442 0.558
K74.5 Biliary cirrhosis, unspecified
0.000 0.443 0.557
M24.1 Other articular cartilage disorders
0.000 0.443 0.557
M82.10 Osteoporosis in endocrine disorders (Multiple sites)
0.000 0.443 0.557
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.443 0.556
L10 Pemphigus
0.000 0.443 0.556
L14 Bullous disorders in diseases classified elsewhere
0.000 0.443 0.556
J43 Emphysema
0.000 0.444 0.556
K74.3 Primary biliary cirrhosis
0.000 0.446 0.554
H34.2 Other retinal artery occlusions
0.000 0.447 0.553
K52.1 Toxic gastro-enteritis and colitis
0.000 0.448 0.552
M49.5 Collapsed vertebra in diseases classified elsewhere
0.000 0.451 0.549
J67 Hypersensitivity pneumonitis due to organic dust
0.000 0.454 0.546
M60.0 Infective myositis
0.000 0.455 0.545
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)
0.000 0.458 0.542
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.000 0.458 0.542
M31.1 Thrombotic microangiopathy
0.000 0.460 0.540
L94.2 Calcinosis cutis
0.000 0.461 0.539
L92 Granulomatous disorders of skin and subcutaneous tissue
0.000 0.465 0.535
K75.0 Abscess of liver
0.000 0.466 0.534
M65.14 Other infective (teno)synovitis (Hand)
0.000 0.466 0.533
J95-J99 Other diseases of the respiratory system
0.000 0.467 0.533
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)
0.000 0.469 0.531
J20 Acute bronchitis
0.000 0.471 0.529
L55 Sunburn
0.000 0.472 0.528
H33 Retinal detachments and breaks
0.000 0.472 0.528
J84.0 Alveolar and parietoalveolar conditions
0.000 0.475 0.525
J45.0 Predominantly allergic asthma
0.000 0.475 0.525
K82.2 Perforation of gallbladder
0.000 0.476 0.524
K72.0 Acute and subacute hepatic failure
0.000 0.477 0.523
M82.11 Osteoporosis in endocrine disorders (Shoulder region)
0.000 0.477 0.523
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.000 0.477 0.523
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.000 0.479 0.521
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.000 0.479 0.521
M83 Adult osteomalacia
0.000 0.480 0.520
H34.1 Central retinal artery occlusion
0.000 0.480 0.520
J37.0 Chronic laryngitis
0.000 0.481 0.519
M63 Disorders of muscle in diseases classified elsewhere
0.000 0.483 0.516
M61 Calcification and ossification of muscle
0.000 0.483 0.516
J37.1 Chronic laryngotracheitis
0.000 0.484 0.516
K81 Cholecystitis
0.000 0.485 0.515
M49.8 Spondylopathy in other diseases classified elsewhere
0.000 0.485 0.514
M49.4 Neuropathic spondylopathy
0.000 0.485 0.514
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere
0.000 0.485 0.514
M49.2 Enterobacterial spondylitis
0.000 0.485 0.514
M49.1 Brucella spondylitis
0.000 0.485 0.514
M49.0 Tuberculosis of spine
0.000 0.485 0.514
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.486 0.514
M06.18 Adult-onset Still's disease (Other)
0.000 0.486 0.514
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.486 0.514
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.486 0.514
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.486 0.514
M06.14 Adult-onset Still's disease (Hand)
0.000 0.486 0.514
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.486 0.514
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.486 0.514
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.486 0.514
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.486 0.514
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.486 0.514
M06.28 Rheumatoid bursitis (Other)
0.000 0.486 0.514
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.486 0.514
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.486 0.514
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.486 0.514
M06.24 Rheumatoid bursitis (Hand)
0.000 0.486 0.514
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.486 0.514
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.486 0.514
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.486 0.514
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.486 0.514
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.486 0.514
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.486 0.514
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.486 0.514
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.486 0.514
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.486 0.514
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.486 0.514
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.486 0.514
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.486 0.514
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.486 0.514
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
M08.9 Juvenile arthritis, unspecified
0.000 0.486 0.514
M08.8 Other juvenile arthritis
0.000 0.486 0.514
M08.4 Pauciarticular juvenile arthritis
0.000 0.486 0.514
M08.3 Juvenile polyarthritis (seronegative)
0.000 0.486 0.514
M08.2 Juvenile arthritis with systemic onset
0.000 0.486 0.514
M08.1 Juvenile ankylosing spondylitis
0.000 0.486 0.514
M08.0 Juvenile rheumatoid arthritis
0.000 0.486 0.514
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.000 0.486 0.514
M09.2 Juvenile arthritis in ulcerative colitis
0.000 0.486 0.514

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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