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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2844502
log Bayes Factor = 237.343
Chromosome 6   position 31,445,216  (GRCh37) Explore rs2844502 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
D64.9 Anaemia, unspecified
1.000 0.000 0.000
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
E10.1 With ketoacidosis
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E14 Unspecified diabetes mellitus
1.000 0.000 0.000
E11 Non-insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
M35 Other systemic involvement of connective tissue
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
1.000 0.000 0.000
J45.9 Asthma, unspecified
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
H36.0 Diabetic retinopathy
1.000 0.000 0.000
D64 Other anaemias
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
D60-D64 Aplastic and other anaemias
1.000 0.000 0.000
E11.9 Without complications
1.000 0.000 0.000
M06 Other rheumatoid arthritis
1.000 0.000 0.000
E14.3 With ophthalmic complications
1.000 0.000 0.000
M35.0 Sicca syndrome [Sjogren]
1.000 0.000 0.000
K90 Intestinal malabsorption
1.000 0.000 0.000
E10.4 With neurological complications
1.000 0.000 0.000
E10.2 With renal complications
0.998 0.002 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.997 0.003 0.000
K90.9 Intestinal malabsorption, unspecified
0.997 0.003 0.000
M35.3 Polymyalgia rheumatica
0.997 0.003 0.000
Chapter VIII Diseases of the ear and mastoid process
0.997 0.003 0.000
D80-D89 Certain disorders involving the immune mechanism
0.996 0.004 0.000
E16 Other disorders of pancreatic internal secretion
0.996 0.004 0.000
J45 Asthma
0.996 0.004 0.000
E11.3 With ophthalmic complications
0.995 0.005 0.000
H60-H62 Diseases of external ear
0.994 0.006 0.000
J40-J47 Chronic lower respiratory diseases
0.994 0.006 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.994 0.006 0.000
E16.2 Hypoglycaemia, unspecified
0.993 0.007 0.000
E14.9 Without complications
0.991 0.009 0.000
Chapter X Diseases of the respiratory system
0.990 0.010 0.000
E50-E64 Other nutritional deficiencies
0.988 0.012 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.014 0.986
M34 Systemic sclerosis
0.986 0.014 0.000
E20-E35 Disorders of other endocrine glands
0.986 0.014 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.986 0.014 0.000
H61 Other disorders of external ear
0.983 0.017 0.000
E06 Thyroiditis
0.983 0.017 0.000
E70-E90 Metabolic disorders
0.982 0.018 0.000
E27 Other disorders of adrenal gland
0.982 0.018 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.979 0.021 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.979 0.021 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.977 0.023 0.000
E27.1 Primary adrenocortical insufficiency
0.975 0.025 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.974 0.026 0.000
M65-M68 Disorders of synovium and tendon
0.974 0.026 0.000
Q66 Congenital deformities of feet
0.972 0.028 0.000
M60-M63 Disorders of muscles
0.968 0.032 0.000
Q66.8 Other congenital deformities of feet
0.966 0.034 0.000
E06.3 Autoimmune thyroiditis
0.965 0.035 0.000
E89.0 Postprocedural hypothyroidism
0.964 0.036 0.000
M05 Seropositive rheumatoid arthritis
0.963 0.037 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.962 0.038 0.000
J46 Status asthmaticus
0.962 0.038 0.000
K90-K93 Other diseases of the digestive system
0.957 0.043 0.000
D86 Sarcoidosis
0.955 0.045 0.000
Chapter XI Diseases of the digestive system
0.954 0.046 0.000
K70-K77 Diseases of liver
0.954 0.046 0.000
K75 Other inflammatory liver diseases
0.950 0.050 0.000
K75.4 Autoimmune hepatitis
0.950 0.050 0.000
E10.5 With peripheral circulatory complications
0.944 0.056 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.944 0.056 0.000
H61.2 Impacted cerumen
0.943 0.057 0.000
E53 Deficiency of other B group vitamins
0.939 0.061 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.937 0.063 0.000
M67 Other disorders of synovium and tendon
0.936 0.064 0.000
D61 Other aplastic anaemias
0.933 0.067 0.000
K74 Fibrosis and cirrhosis of liver
0.931 0.069 0.000
M10 Gout
0.931 0.069 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.931 0.069 0.000
D86.9 Sarcoidosis, unspecified
0.929 0.071 0.000
E78.2 Mixed hyperlipidaemia
0.928 0.072 0.000
E10.8 With unspecified complications
0.928 0.072 0.000
E89.3 Postprocedural hypopituitarism
0.926 0.074 0.000
M31 Other necrotising vasculopathies
0.926 0.074 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.923 0.077 0.000
M67.1 Other contracture of tendon (sheath)
0.922 0.078 0.000
J33 Nasal polyp
0.922 0.078 0.000
J33.0 Polyp of nasal cavity
0.921 0.079 0.000
I83 Varicose veins of lower extremities
0.000 0.080 0.920
J44 Other chronic obstructive pulmonary disease
0.919 0.081 0.000
E11.5 With peripheral circulatory complications
0.918 0.082 0.000
H60 Otitis externa
0.918 0.082 0.000
M62 Other disorders of muscle
0.918 0.082 0.000
E10.0 With coma
0.916 0.084 0.000
J33.9 Nasal polyp, unspecified
0.915 0.085 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.086 0.914
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.905 0.095 0.000
M70-M79 Other soft tissue disorders
0.905 0.095 0.000
M75 Shoulder lesions
0.904 0.096 0.000
M34.9 Systemic sclerosis, unspecified
0.901 0.099 0.000
M80-M85 Disorders of bone density and structure
0.900 0.100 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.897 0.103 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.897 0.103 0.000
E61 Deficiency of other nutrient elements
0.894 0.106 0.000
M75.0 Adhesive capsulitis of shoulder
0.893 0.107 0.000
E53.8 Deficiency of other specified B group vitamins
0.891 0.109 0.000
M66 Spontaneous rupture of synovium and tendon
0.890 0.110 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.886 0.114 0.000
J30-J39 Other diseases of upper respiratory tract
0.884 0.116 0.000
D80 Immunodeficiency with predominantly antibody defects
0.883 0.117 0.000
M62.8 Other specified disorders of muscle
0.883 0.117 0.000
M75.5 Bursitis of shoulder
0.881 0.119 0.000
Q44.6 Cystic disease of liver
0.880 0.120 0.000
M34.1 CR(E)ST syndrome
0.879 0.121 0.000
H90-H95 Other disorders of ear
0.878 0.122 0.000
H61.0 Perichondritis of external ear
0.877 0.123 0.000
K74.3 Primary biliary cirrhosis
0.876 0.124 0.000
M34.8 Other forms of systemic sclerosis
0.872 0.128 0.000
M30 Polyarteritis nodosa and related conditions
0.871 0.129 0.000
M10.9 Gout, unspecified
0.868 0.132 0.000
E10.7 With multiple complications
0.865 0.135 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.865 0.135 0.000
M06.8 Other specified rheumatoid arthritis
0.864 0.136 0.000
K74.5 Biliary cirrhosis, unspecified
0.862 0.138 0.000
M80 Osteoporosis with pathological fracture
0.856 0.144 0.000
M32 Systemic lupus erythematosus
0.856 0.144 0.000
D61.9 Aplastic anaemia, unspecified
0.855 0.145 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.854 0.146 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.851 0.149 0.000
M75.3 Calcific tendinitis of shoulder
0.850 0.150 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.848 0.152 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.848 0.152 0.000
E14.8 With unspecified complications
0.848 0.152 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.847 0.153 0.000
D55-D59 Haemolytic anaemias
0.846 0.154 0.000
E11.1 With ketoacidosis
0.846 0.154 0.000
M35.1 Other overlap syndromes
0.846 0.154 0.000
M60 Myositis
0.844 0.156 0.000
K72 Hepatic failure, not elsewhere classified
0.843 0.157 0.000
H36 Retinal disorders in diseases classified elsewhere
0.842 0.158 0.000
E88 Other metabolic disorders
0.837 0.163 0.000
E55 Vitamin D deficiency
0.835 0.165 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.834 0.166 0.000
E14.2 Withrenal complications
0.833 0.167 0.000
Q50-Q56 Congenital malformations of genital organs
0.832 0.168 0.000
E10.6 With other specified complications
0.832 0.168 0.000
E14.6 With other specified complications
0.830 0.170 0.000
H61.3 Acquired stenosis of external ear canal
0.829 0.171 0.000
E61.1 Iron deficiency
0.828 0.172 0.000
H90 Conductive and sensorineural hearing loss
0.827 0.173 0.000
E14.5 With peripheral circulatory complications
0.824 0.176 0.000
Q39 Congenital malformations of oesophagus
0.823 0.177 0.000
E51 Thiamine deficiency
0.821 0.179 0.000
E14.1 With ketoacidosis
0.820 0.180 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.817 0.183 0.000
D82 Immunodeficiency associated with other major defects
0.817 0.183 0.000
M62.81 Other specified disorders of muscle (Shoulder region)
0.817 0.183 0.000
D50-D53 Nutritional anaemias
0.815 0.185 0.000
E06.9 Thyroiditis, unspecified
0.814 0.186 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.813 0.187 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.813 0.187 0.000
H60.1 Cellulitis of external ear
0.813 0.187 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.812 0.188 0.000
H90.3 Sensorineural hearing loss, bilateral
0.812 0.188 0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)
0.807 0.193 0.000
D83 Common variable immunodeficiency
0.806 0.194 0.000
M67.4 Ganglion
0.806 0.194 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.804 0.196 0.000
E05.8 Other thyrotoxicosis
0.803 0.197 0.000
E89.1 Postprocedural hypoinsulinaemia
0.801 0.199 0.000
H60.3 Other infective otitis externa
0.801 0.199 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.796 0.204 0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.793 0.207 0.000
M10.99 Gout, unspecified (Site unspecified)
0.791 0.209 0.000
E78.4 Other hyperlipidaemia
0.790 0.210 0.000
E21.3 Hyperparathyroidism, unspecified
0.787 0.213 0.000
K90.8 Other intestinal malabsorption
0.787 0.213 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.786 0.214 0.000
Q66.9 Congenital deformity of feet, unspecified
0.785 0.215 0.000
K74.6 Other and unspecified cirrhosis of liver
0.783 0.217 0.000
M10.94 Gout, unspecified (Hand)
0.783 0.217 0.000
M34.0 Progressive systemic sclerosis
0.782 0.218 0.000
D64.8 Other specified anaemias
0.782 0.218 0.000
M82 Osteoporosis in diseases classified elsewhere
0.781 0.219 0.000
D64.3 Other sideroblastic anaemias
0.779 0.220 0.000
H61.8 Other specified disorders of external ear
0.779 0.221 0.000
M62.86 Other specified disorders of muscle (Lower leg)
0.778 0.222 0.000
E24 Cushing's syndrome
0.775 0.225 0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.775 0.225 0.000
J45.1 Nonallergic asthma
0.775 0.225 0.000
E79 Disorders of purine and pyrimidine metabolism
0.774 0.226 0.000
M60.9 Myositis, unspecified
0.773 0.227 0.000
E11.7 With multiple complications
0.773 0.227 0.000
E11.0 With coma
0.773 0.227 0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)
0.771 0.229 0.000
D61.1 Drug-induced aplastic anaemia
0.770 0.230 0.000
K73 Chronic hepatitis, not elsewhere classified
0.767 0.233 0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest
0.766 0.234 0.000
D84 Other immunodeficiencies
0.763 0.237 0.000
M12 Other specific arthropathies
0.761 0.239 0.000
E74 Other disorders of carbohydrate metabolism
0.760 0.240 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.760 0.240 0.000
Q66.7 Pes cavus
0.758 0.242 0.000
G59.0 Diabetic mononeuropathy
0.757 0.243 0.000
M31.6 Other giant cell arteritis
0.757 0.243 0.000
D80.1 Nonfamilial hypogammaglobulinaemia
0.755 0.245 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.755 0.245 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.754 0.246 0.000
G56 Mononeuropathies of upper limb
0.753 0.247 0.000
Q44.5 Other congenital malformations of bile ducts
0.751 0.249 0.000
E11.6 With other specified complications
0.749 0.250 0.000
G56.0 Carpal tunnel syndrome
0.748 0.252 0.000
E27.9 Disorder of adrenal gland, unspecified
0.747 0.253 0.000
M08 Juvenile arthritis
0.745 0.255 0.000
E53.9 Vitamin B deficiency, unspecified
0.743 0.257 0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere
0.743 0.257 0.000
M05.1 Rheumatoid lung disease
0.742 0.258 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.741 0.259 0.000
E20 Hypoparathyroidism
0.740 0.260 0.000
M14 Arthropathies in other diseases classified elsewhere
0.737 0.263 0.000
D86.0 Sarcoidosis of lung
0.734 0.266 0.000
K72.9 Hepatic failure, unspecified
0.734 0.266 0.000
E21.4 Other specified disorders of parathyroid gland
0.733 0.267 0.000
Q35-Q37 Cleft lip and cleft palate
0.733 0.267 0.000
H65-H75 Diseases of middle ear and mastoid
0.732 0.268 0.000
K75.8 Other specified inflammatory liver diseases
0.731 0.269 0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.731 0.269 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.731 0.269 0.000
M66.0 Rupture of popliteal cyst
0.730 0.270 0.000
M67.0 Short Achilles tendon (acquired)
0.729 0.271 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.729 0.271 0.000
Q45 Other congenital malformations of digestive system
0.729 0.271 0.000
M66.5 Spontaneous rupture of unspecified tendon
0.729 0.271 0.000
E78.6 Lipoprotein deficiency
0.728 0.272 0.000
H30-H36 Disorders of choroid and retina
0.728 0.272 0.000
M31.3 Wegener's granulomatosis
0.728 0.272 0.000
D86.1 Sarcoidosis of lymph nodes
0.727 0.273 0.000
E55.9 Vitamin D deficiency, unspecified
0.725 0.275 0.000
E31 Polyglandular dysfunction
0.725 0.275 0.000
J60-J70 Lung diseases due to external agents
0.725 0.275 0.000
M10.0 Idiopathic gout
0.724 0.276 0.000
E40-E46 Malnutrition
0.724 0.276 0.000
H61.1 Non-infective disorders of pinna
0.722 0.278 0.000
D89.1 Cryoglobulinaemia
0.722 0.278 0.000
Q00-Q07 Congenital malformations of the nervous system
0.721 0.279 0.000
D89.9 Disorder involving the immune mechanism, unspecified
0.721 0.279 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.721 0.279 0.000
E78.8 Other disorders of lipoprotein metabolism
0.719 0.281 0.000
D56 Thalassaemia
0.719 0.281 0.000
M35.2 Behcet's disease
0.719 0.281 0.000
H60.2 Malignant otitis externa
0.719 0.281 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
E14.7 With multiple complications
0.717 0.283 0.000
E14.0 With coma
0.717 0.283 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.717 0.283 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.717 0.283 0.000
M35.5 Multifocal fibrosclerosis
0.717 0.283 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.717 0.283 0.000
D64.4 Congenital dyserythropoietic anaemia
0.717 0.283 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.717 0.283 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.717 0.283 0.000
D64.0 Hereditary sideroblastic anaemia
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E03.1 Congenital hypothyroidism without goitre
0.717 0.283 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.717 0.283 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.717 0.283 0.000
M06.2 Rheumatoid bursitis
0.717 0.283 0.000
M06.1 Adult-onset Still's disease
0.717 0.283 0.000
K90.3 Pancreatic steatorrhoea
0.717 0.283 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.717 0.283 0.000
K90.1 Tropical sprue
0.717 0.283 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.717 0.283 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.716 0.284 0.000
E72 Other disorders of amino-acid metabolism
0.715 0.285 0.000
E15 Nondiabetic hypoglycaemic coma
0.715 0.285 0.000
D86.8 Sarcoidosis of other and combined sites
0.715 0.285 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.715 0.285 0.000
D81 Combined immunodeficiencies
0.714 0.286 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.714 0.286 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.714 0.286 0.000
E16.4 Abnormal secretion of gastrin
0.714 0.286 0.000
E16.3 Increased secretion of glucagon
0.714 0.286 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.712 0.287 0.000
H92 Otalgia and effusion of ear
0.711 0.289 0.000
Q68 Other congenital musculoskeletal deformities
0.710 0.290 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.709 0.291 0.000
E63 Other nutritional deficiencies
0.709 0.291 0.000
E50 Vitamin A deficiency
0.709 0.291 0.000
E60 Dietary zinc deficiency
0.709 0.291 0.000
E59 Dietary selenium deficiency
0.709 0.291 0.000
E54 Ascorbic acid deficiency
0.709 0.291 0.000
E52 Niacin deficiency [pellagra]
0.709 0.291 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.707 0.293 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.707 0.293 0.000
E32 Diseases of thymus
0.707 0.293 0.000
E30 Disorders of puberty, not elsewhere classified
0.707 0.293 0.000
M75.8 Other shoulder lesions
0.707 0.293 0.000
E70 Disorders of aromatic amino-acid metabolism
0.706 0.294 0.000
H60.4 Cholesteatoma of external ear
0.706 0.294 0.000
E11.8 With unspecified complications
0.706 0.294 0.000
E06.4 Drug-induced thyroiditis
0.704 0.295 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.704 0.295 0.000
E06.1 Subacute thyroiditis
0.704 0.295 0.000
E06.0 Acute thyroiditis
0.704 0.295 0.000
E77 Disorders of glycoprotein metabolism
0.704 0.296 0.000
E76 Disorders of glycosaminoglycan metabolism
0.704 0.296 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.704 0.296 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.704 0.296 0.000
E27.5 Adrenomedullary hyperfunction
0.704 0.296 0.000
E27.0 Other adrenocortical overactivity
0.704 0.296 0.000
J45.8 Mixed asthma
0.704 0.296 0.000
M67.43 Ganglion, wrist
0.704 0.296 0.000
Q39.6 Diverticulum of oesophagus
0.704 0.296 0.000
M31.0 Hypersensitivity angiitis
0.703 0.297 0.000
M31.1 Thrombotic microangiopathy
0.702 0.298 0.000
Q75 Other congenital malformations of skull and face bones
0.702 0.298 0.000
Q73 Reduction defects of unspecified limb
0.702 0.298 0.000
Q72 Reduction defects of lower limb
0.702 0.298 0.000
Q71 Reduction defects of upper limb
0.702 0.298 0.000
Q70 Syndactyly
0.702 0.298 0.000
Q69 Polydactyly
0.702 0.298 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.702 0.298 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.702 0.298 0.000
E89.5 Postprocedural testicular hypofunction
0.702 0.298 0.000
M06.3 Rheumatoid nodule
0.701 0.298 0.000
M66.3 Spontaneous rupture of flexor tendons
0.701 0.299 0.000
E51.2 Wernicke's encephalopathy
0.701 0.299 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.701 0.299 0.000
M62.6 Muscle strain
0.700 0.300 0.000
H95.1 Other disorders following mastoidectomy
0.699 0.301 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.698 0.302 0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine
0.698 0.302 0.000
Q76 Congenital malformations of spine and bony thorax
0.698 0.302 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.697 0.303 0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified
0.697 0.303 0.000
Q66.6 Other congenital valgus deformities of feet
0.697 0.303 0.000
Q66.5 Congenital pes planus
0.697 0.303 0.000
Q66.4 Talipes calcaneovalgus
0.697 0.303 0.000
Q66.1 Talipes calcaneovarus
0.697 0.303 0.000
E07 Other disorders of thyroid
0.696 0.304 0.000
M82.1 Osteoporosis in endocrine disorders
0.696 0.304 0.000
E84 Cystic fibrosis
0.695 0.305 0.000
J41 Simple and mucopurulent chronic bronchitis
0.695 0.305 0.000
H60.5 Acute otitis externa, non-infective
0.694 0.306 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.694 0.306 0.000
M61 Calcification and ossification of muscle
0.694 0.306 0.000
Q54 Hypospadias
0.693 0.307 0.000
J37 Chronic laryngitis and laryngotracheitis
0.693 0.307 0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral
0.693 0.307 0.000
J47 Bronchiectasis
0.693 0.307 0.000
E25 Adrenogenital disorders
0.691 0.309 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.690 0.309 0.000
M05.2 Rheumatoid vasculitis
0.690 0.309 0.000
M05.0 Felty's syndrome
0.690 0.309 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.690 0.310 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.690 0.310 0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)
0.690 0.310 0.000
M05.8 Other seropositive rheumatoid arthritis
0.688 0.311 0.000
D82.1 Di George's syndrome
0.688 0.312 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.686 0.314 0.000
Q65 Congenital deformities of hip
0.686 0.314 0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.685 0.314 0.000
M35.7 Hypermobility syndrome
0.685 0.314 0.000
K77 Liver disorders in diseases classified elsewhere
0.684 0.316 0.000
K72.0 Acute and subacute hepatic failure
0.683 0.317 0.000
M66.2 Spontaneous rupture of extensor tendons
0.683 0.317 0.000
E34 Other endocrine disorders
0.682 0.318 0.000
E56 Other vitamin deficiencies
0.682 0.318 0.000
K75.2 Nonspecific reactive hepatitis
0.681 0.319 0.000
K75.1 Phlebitis of portal vein
0.681 0.319 0.000
Q52 Other congenital malformations of female genitalia
0.681 0.319 0.000
M62.82 Other specified disorders of muscle (Upper arm)
0.680 0.320 0.000
Chapter VI Diseases of the nervous system
0.680 0.320 0.000
Q78 Other osteochondrodysplasias
0.680 0.320 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.680 0.320 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.321 0.679
M60.99 Myositis, unspecified (Site unspecified)
0.679 0.321 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.678 0.322 0.000
G56.8 Other mononeuropathies of upper limb
0.678 0.322 0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified
0.676 0.324 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.674 0.326 0.000
D51 Vitamin B12 deficiency anaemia
0.674 0.326 0.000
E53.1 Pyridoxine deficiency
0.673 0.327 0.000
E53.0 Riboflavin deficiency
0.673 0.327 0.000
Q55 Other congenital malformations of male genital organs
0.673 0.327 0.000
E78.3 Hyperchylomicronaemia
0.671 0.328 0.000
E73 Lactose intolerance
0.671 0.329 0.000
M67.9 Disorder of synovium and tendon, unspecified
0.671 0.329 0.000
M67.3 Transient synovitis
0.671 0.329 0.000
D61.0 Constitutional aplastic anaemia
0.671 0.329 0.000
D83.9 Common variable immunodeficiency, unspecified
0.670 0.330 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.670 0.330 0.000
Q66.0 Talipes equinovarus
0.669 0.331 0.000
E78.1 Pure hyperglyceridaemia
0.669 0.331 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.669 0.331 0.000
D61.8 Other specified aplastic anaemias
0.669 0.331 0.000
D61.3 Idiopathic aplastic anaemia
0.669 0.331 0.000
D61.2 Aplastic anaemia due to other external agents
0.669 0.331 0.000
M11 Other crystal arthropathies
0.669 0.331 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.669 0.331 0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.668 0.332 0.000
K74.4 Secondary biliary cirrhosis
0.668 0.332 0.000
K74.2 Hepatic fibrosis with hepatic sclerosis
0.668 0.332 0.000
K74.1 Hepatic sclerosis
0.668 0.332 0.000
M10.4 Other secondary gout
0.668 0.332 0.000
M10.3 Gout due to impairment of renal function
0.668 0.332 0.000
M10.2 Drug-induced gout
0.668 0.332 0.000
M10.1 Lead-induced gout
0.668 0.332 0.000
M31.7 Microscopic polyangiitis
0.668 0.332 0.000
E88.2 Lipomatosis, not elsewhere classified
0.667 0.333 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.667 0.333 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.667 0.333 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.667 0.333 0.000
E06.5 Other chronic thyroiditis
0.665 0.335 0.000
M31.8 Other specified necrotising vasculopathies
0.664 0.336 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.664 0.336 0.000
M31.2 Lethal midline granuloma
0.664 0.336 0.000
L40.9 Psoriasis, unspecified
0.000 0.336 0.664
Q39.9 Congenital malformation of oesophagus, unspecified
0.662 0.338 0.000
E11.4 With neurological complications
0.662 0.338 0.000
Q44.7 Other congenital malformations of liver
0.662 0.338 0.000
Q44.4 Choledochal cyst
0.662 0.338 0.000
Q44.3 Congenital stenosis and stricture of bile ducts
0.662 0.338 0.000
Q44.2 Atresia of bile ducts
0.662 0.338 0.000
Q44.1 Other congenital malformations of gallbladder
0.662 0.338 0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder
0.662 0.338 0.000
J95-J99 Other diseases of the respiratory system
0.659 0.341 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.658 0.342 0.000
M62.4 Contracture of muscle
0.658 0.342 0.000
M62.3 Immobility syndrome (paraplegic)
0.658 0.342 0.000
M62.2 Ischaemic infarction of muscle
0.658 0.342 0.000
G52 Disorders of other cranial nerves
0.654 0.346 0.000
E85 Amyloidosis
0.654 0.346 0.000
D53 Other nutritional anaemias
0.654 0.346 0.000
E21.2 Other hyperparathyroidism
0.653 0.347 0.000
M66.4 Spontaneous rupture of other tendons
0.651 0.349 0.000
H65 Nonsuppurative otitis media
0.651 0.349 0.000
Q66.3 Other congenital varus deformities of feet
0.650 0.350 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.649 0.351 0.000
E14.4 With neurological complications
0.648 0.351 0.000
M10.92 Gout, unspecified (Upper arm)
0.648 0.351 0.000
M62.83 Other specified disorders of muscle (Forearm)
0.647 0.353 0.000
M35.8 Other specified systemic involvement of connective tissue
0.647 0.353 0.000
Q43 Other congenital malformations of intestine
0.646 0.354 0.000
E24.2 Drug-induced Cushing's syndrome
0.646 0.354 0.000
E89.4 Postprocedural ovarian failure
0.646 0.354 0.000
D59 Acquired haemolytic anaemia
0.646 0.354 0.000
D89.0 Polyclonal hypergammaglobulinaemia
0.645 0.355 0.000
H60.9 Otitis externa, unspecified
0.644 0.355 0.000
E27.8 Other specified disorders of adrenal gland
0.643 0.357 0.000
M83 Adult osteomalacia
0.643 0.357 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.642 0.358 0.000
Chapter VII Diseases of the eye and adnexa
0.642 0.358 0.000
E61.9 Deficiency of nutrient element, unspecified
0.641 0.359 0.000
E61.8 Deficiency of other specified nutrient elements
0.641 0.359 0.000
E61.7 Deficiency of multiple nutrient elements
0.641 0.359 0.000
E61.6 Vanadium deficiency
0.641 0.359 0.000
E61.5 Molybdenum deficiency
0.641 0.359 0.000
E61.4 Chromium deficiency
0.641 0.359 0.000
E61.3 Manganese deficiency
0.641 0.359 0.000
E61.0 Copper deficiency
0.641 0.359 0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.640 0.360 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.640 0.360 0.000
M66.1 Rupture of synovium
0.638 0.362 0.000
M32.0 Drug-induced systemic lupus erythematosus
0.637 0.362 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.636 0.364 0.000
H30 Chorioretinal inflammation
0.636 0.364 0.000
E61.2 Magnesium deficiency
0.635 0.365 0.000
E11.2 With renal complications
0.635 0.365 0.000
M40-M43 Deforming dorsopathies
0.633 0.367 0.000
D80.8 Other immunodeficiencies with predominantly antibody defects
0.633 0.367 0.000
D80.7 Transient hypogammaglobulinaemia of infancy
0.633 0.367 0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.633 0.367 0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.633 0.367 0.000
D80.0 Hereditary hypogammaglobulinaemia
0.633 0.367 0.000
M62.87 Other specified disorders of muscle (Ankle and foot)
0.633 0.367 0.000
G56.1 Other lesions of median nerve
0.633 0.367 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.632 0.368 0.000
Q54.0 Hypospadias, balanic
0.632 0.368 0.000
M30.0 Polyarteritis nodosa
0.632 0.368 0.000
G54 Nerve root and plexus disorders
0.632 0.368 0.000
H92.1 Otorrhoea
0.631 0.368 0.000
E23 Hypofunction and other disorders of pituitary gland
0.631 0.369 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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