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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1150755
log Bayes Factor = 380.176
Chromosome 6   position 32,038,550  (GRCh37) Explore rs1150755 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
D64.9 Anaemia, unspecified
1.000 0.000 0.000
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
E10.1 With ketoacidosis
1.000 0.000 0.000
E16.2 Hypoglycaemia, unspecified
1.000 0.000 0.000
H36.0 Diabetic retinopathy
1.000 0.000 0.000
J45.9 Asthma, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
M35.0 Sicca syndrome [Sjogren]
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E14 Unspecified diabetes mellitus
1.000 0.000 0.000
E11 Non-insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
R31 Unspecified haematuria
0.000 0.000 1.000
D50-D53 Nutritional anaemias
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
J40-J47 Chronic lower respiratory diseases
1.000 0.000 0.000
K70-K77 Diseases of liver
1.000 0.000 0.000
N00-N08 Glomerular diseases
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
K90 Intestinal malabsorption
1.000 0.000 0.000
D60-D64 Aplastic and other anaemias
1.000 0.000 0.000
H30-H36 Disorders of choroid and retina
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
J44 Other chronic obstructive pulmonary disease
1.000 0.000 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
1.000 0.000 0.000
J45 Asthma
1.000 0.000 0.000
G50-G59 Nerve, nerve root and plexus disorders
1.000 0.000 0.000
E14.3 With ophthalmic complications
1.000 0.000 0.000
D64 Other anaemias
1.000 0.000 0.000
M35 Other systemic involvement of connective tissue
1.000 0.000 0.000
E16 Other disorders of pancreatic internal secretion
1.000 0.000 0.000
H36 Retinal disorders in diseases classified elsewhere
1.000 0.000 0.000
K75 Other inflammatory liver diseases
1.000 0.000 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
1.000 0.000 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
N18 Chronic renal failure
1.000 0.000 0.000
N17-N19 Renal failure
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
I73 Other peripheral vascular diseases
1.000 0.000 0.000
E10.4 With neurological complications
1.000 0.000 0.000
E89.0 Postprocedural hypothyroidism
1.000 0.000 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
1.000 0.000 0.000
K75.4 Autoimmune hepatitis
1.000 0.000 0.000
G56 Mononeuropathies of upper limb
1.000 0.000 0.000
M15-M19 Arthrosis
1.000 0.000 0.000
G56.0 Carpal tunnel syndrome
1.000 0.000 0.000
E70-E90 Metabolic disorders
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
E10.2 With renal complications
0.999 0.001 0.000
M18 Arthrosis of first carpometacarpal joint
0.999 0.001 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.999 0.001 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.999 0.001 0.000
D50 Iron deficiency anaemia
0.999 0.001 0.000
K90-K93 Other diseases of the digestive system
0.999 0.001 0.000
E20-E35 Disorders of other endocrine glands
0.999 0.001 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.999 0.001 0.000
E11.3 With ophthalmic complications
0.998 0.002 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.998 0.002 0.000
Chapter IX Diseases of the circulatory system
0.998 0.002 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.998 0.002 0.000
Chapter XX External causes of morbidity and mortality
0.998 0.002 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.998 0.002 0.000
N04 Nephrotic syndrome
0.998 0.002 0.000
E27.1 Primary adrenocortical insufficiency
0.998 0.002 0.000
D50.9 Iron deficiency anaemia, unspecified
0.998 0.002 0.000
E27 Other disorders of adrenal gland
0.997 0.003 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.997 0.003 0.000
D51 Vitamin B12 deficiency anaemia
0.997 0.003 0.000
I73.9 Peripheral vascular disease, unspecified
0.997 0.003 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.996 0.004 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.995 0.005 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.995 0.005 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.995 0.005 0.000
M05-M14 Inflammatory polyarthropathies
0.994 0.006 0.000
K73 Chronic hepatitis, not elsewhere classified
0.994 0.006 0.000
E14.9 Without complications
0.994 0.006 0.000
K90.9 Intestinal malabsorption, unspecified
0.993 0.007 0.000
N04.9 Unspecified
0.993 0.007 0.000
E11.5 With peripheral circulatory complications
0.993 0.007 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.992 0.008 0.000
G59.0 Diabetic mononeuropathy
0.992 0.008 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.992 0.008 0.000
I73.0 Raynaud's syndrome
0.991 0.009 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.990 0.010 0.000
N18.9 Chronic renal failure, unspecified
0.989 0.011 0.000
D61 Other aplastic anaemias
0.987 0.013 0.000
L10-L14 Bullous disorders
0.987 0.013 0.000
H06.2 Dysthyroid exophthalmos
0.987 0.013 0.000
M86-M90 Other osteopathies
0.986 0.014 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.986 0.014 0.000
L03 Cellulitis
0.986 0.014 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.986 0.014 0.000
L08 Other local infections of skin and subcutaneous tissue
0.983 0.017 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.982 0.018 0.000
E06 Thyroiditis
0.982 0.018 0.000
E11.9 Without complications
0.982 0.018 0.000
H34 Retinal vascular occlusions
0.982 0.018 0.000
A30-A49 Other bacterial diseases
0.981 0.019 0.000
H02 Other disorders of eyelid
0.981 0.019 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.981 0.019 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.980 0.020 0.000
N05 Unspecified nephritic syndrome
0.980 0.020 0.000
D80-D89 Certain disorders involving the immune mechanism
0.979 0.021 0.000
D61.9 Aplastic anaemia, unspecified
0.978 0.022 0.000
C91 Lymphoid leukaemia
0.977 0.023 0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.977 0.023 0.000
M86 Osteomyelitis
0.977 0.023 0.000
L13 Other bullous disorders
0.977 0.023 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.976 0.024 0.000
W00-W19 Falls
0.976 0.024 0.000
M06 Other rheumatoid arthritis
0.976 0.024 0.000
I74 Arterial embolism and thrombosis
0.975 0.025 0.000
I10-I15 Hypertensive diseases
0.975 0.025 0.000
A41 Other septicaemia
0.973 0.027 0.000
B35-B49 Mycoses
0.971 0.029 0.000
I12 Hypertensive renal disease
0.970 0.030 0.000
L03.1 Cellulitis of other parts of limb
0.970 0.030 0.000
L13.0 Dermatitis herpetiformis
0.970 0.030 0.000
E10.5 With peripheral circulatory complications
0.970 0.030 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.970 0.030 0.000
W19 Unspecified fall
0.970 0.030 0.000
N18.3 Chronic kidney disease, stage 3
0.969 0.031 0.000
M06.9 Rheumatoid arthritis, unspecified
0.968 0.032 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.967 0.033 0.000
H43-H45 Disorders of vitreous body and globe
0.967 0.033 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.967 0.033 0.000
D69 Purpura and other haemorrhagic conditions
0.965 0.035 0.000
E06.3 Autoimmune thyroiditis
0.965 0.035 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.964 0.036 0.000
I77 Other disorders of arteries and arterioles
0.964 0.036 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.964 0.036 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.962 0.038 0.000
M60-M63 Disorders of muscles
0.961 0.039 0.000
B37 Candidiasis
0.960 0.040 0.000
M23 Internal derangement of knee
0.960 0.040 0.000
D70 Agranulocytosis
0.959 0.041 0.000
H34.8 Other retinal vascular occlusions
0.958 0.042 0.000
A41.9 Septicaemia, unspecified
0.956 0.044 0.000
H43 Disorders of vitreous body
0.956 0.044 0.000
N18.0 End-stage renal disease
0.955 0.045 0.000
K73.9 Chronic hepatitis, unspecified
0.955 0.045 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.955 0.045 0.000
H02.5 Other disorders affecting eyelid function
0.954 0.046 0.000
N05.2 Diffuse membranous glomerulonephritis
0.952 0.048 0.000
C83.3 Large cell (diffuse)
0.951 0.049 0.000
I12.9 Hypertensive renal disease without renal failure
0.950 0.050 0.000
E11.1 With ketoacidosis
0.950 0.050 0.000
M17 Gonarthrosis [arthrosis of knee]
0.949 0.051 0.000
H00.1 Chalazion
0.000 0.052 0.948
W19.9 Unspecified place
0.948 0.052 0.000
B37.8 Candidiasis of other sites
0.948 0.052 0.000
C85.1 B-cell lymphoma, unspecified
0.947 0.053 0.000
H43.1 Vitreous haemorrhage
0.946 0.054 0.000
M23.3 Other meniscus derangements
0.945 0.055 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.945 0.055 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.944 0.056 0.000
D69.6 Thrombocytopenia, unspecified
0.944 0.056 0.000
H02.0 Entropion and trichiasis of eyelid
0.944 0.056 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.057 0.943
M86.9 Osteomyelitis, unspecified
0.942 0.058 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.942 0.058 0.000
K75.8 Other specified inflammatory liver diseases
0.941 0.059 0.000
D50.8 Other iron deficiency anaemias
0.940 0.060 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.939 0.061 0.000
K74 Fibrosis and cirrhosis of liver
0.939 0.061 0.000
H04 Disorders of lachrymal system
0.937 0.063 0.000
E14.8 With unspecified complications
0.937 0.063 0.000
J46 Status asthmaticus
0.932 0.068 0.000
C92 Myeloid leukaemia
0.931 0.069 0.000
D86 Sarcoidosis
0.930 0.070 0.000
C91.1 Chronic lymphocytic leukaemia
0.930 0.070 0.000
M17.1 Other primary gonarthrosis
0.930 0.070 0.000
N18.4 Chronic kidney disease, stage 4
0.928 0.072 0.000
I77.6 Arteritis, unspecified
0.927 0.073 0.000
B25-B34 Other viral diseases
0.926 0.074 0.000
L50-L54 Urticaria and erythema
0.926 0.074 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.926 0.074 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.925 0.075 0.000
L20-L30 Dermatitis and eczema
0.925 0.075 0.000
E10.0 With coma
0.925 0.075 0.000
I12.0 Hypertensive renal disease with renal failure
0.924 0.076 0.000
K72 Hepatic failure, not elsewhere classified
0.921 0.079 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.921 0.079 0.000
N17 Acute renal failure
0.919 0.081 0.000
M10 Gout
0.915 0.085 0.000
H04.1 Other disorders of lachrymal gland
0.914 0.086 0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.914 0.086 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.913 0.087 0.000
B07 Viral warts
0.913 0.087 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.912 0.088 0.000
H53-H54 Visual disturbances and blindness
0.911 0.089 0.000
Chapter VIII Diseases of the ear and mastoid process
0.909 0.091 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.909 0.091 0.000
K74.6 Other and unspecified cirrhosis of liver
0.908 0.092 0.000
C81 Hodgkin's disease
0.908 0.092 0.000
M15 Polyarthrosis
0.907 0.093 0.000
J84 Other interstitial pulmonary diseases
0.903 0.097 0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.903 0.097 0.000
W19.3 Sports and athletics area
0.903 0.097 0.000
L28 Lichen simplex chronicus and prurigo
0.902 0.098 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.902 0.098 0.000
J84.9 Interstitial pulmonary disease, unspecified
0.900 0.100 0.000
M62 Other disorders of muscle
0.900 0.100 0.000
M24 Other specific joint derangements
0.899 0.101 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.899 0.101 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.898 0.102 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.898 0.102 0.000
L03.0 Cellulitis of finger and toe
0.898 0.102 0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.896 0.104 0.000
G30-G32 Other degenerative diseases of the nervous system
0.892 0.108 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.892 0.108 0.000
B37.9 Candidiasis, unspecified
0.892 0.108 0.000
M65-M68 Disorders of synovium and tendon
0.891 0.109 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.891 0.109 0.000
E11.6 With other specified complications
0.890 0.110 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.890 0.110 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.888 0.112 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.888 0.112 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.887 0.113 0.000
E10.8 With unspecified complications
0.886 0.114 0.000
W19.2 School, other institution and public administrative area
0.883 0.117 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.881 0.119 0.000
D86.9 Sarcoidosis, unspecified
0.881 0.119 0.000
L28.0 Lichen simplex chronicus
0.879 0.121 0.000
Y43 Primarily systemic agents
0.879 0.121 0.000
A63.0 Anogenital (venereal) warts
0.877 0.123 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.876 0.124 0.000
H60-H62 Diseases of external ear
0.873 0.127 0.000
B25 Cytomegaloviral disease
0.873 0.127 0.000
M00-M03 Infectious arthropathies
0.872 0.128 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.872 0.128 0.000
N04.1 Focal and segmental glomerular lesions
0.869 0.131 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.868 0.132 0.000
E10.6 With other specified complications
0.867 0.133 0.000
I77.1 Stricture of artery
0.867 0.133 0.000
K50-K52 Noninfective enteritis and colitis
0.853 0.134 0.013
B15-B19 Viral hepatitis
0.866 0.134 0.000
E87.5 Hyperkalaemia
0.866 0.134 0.000
E23 Hypofunction and other disorders of pituitary gland
0.865 0.135 0.000
B00 Herpesviral [herpes simplex] infections
0.864 0.136 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.862 0.138 0.000
V20-V29 Motorcycle rider injured in transport accident
0.861 0.139 0.000
H05 Disorders of orbit
0.860 0.140 0.000
N08.5 Glomerular disorders in systemic connective tissue disorders
0.860 0.140 0.000
E07 Other disorders of thyroid
0.860 0.140 0.000
C88 Malignant immunoproliferative diseases
0.858 0.142 0.000
D68 Other coagulation defects
0.858 0.142 0.000
Y42.7 Androgens and anabolic congeners
0.858 0.142 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.856 0.144 0.000
R30-R39 Symptoms and signs involving the urinary system
0.000 0.144 0.856
N17.9 Acute renal failure, unspecified
0.856 0.144 0.000
C92.0 Acute myeloid leukaemia
0.855 0.145 0.000
E89.2 Postprocedural hypoparathyroidism
0.854 0.146 0.000
D80 Immunodeficiency with predominantly antibody defects
0.854 0.146 0.000
C83.0 Small cell (diffuse)
0.852 0.148 0.000
L52 Erythema nodosum
0.852 0.148 0.000
L92.0 Granuloma annulare
0.851 0.149 0.000
E50-E64 Other nutritional deficiencies
0.851 0.149 0.000
K52 Other non-infective gastro-enteritis and colitis
0.846 0.150 0.004
E11.4 With neurological complications
0.850 0.150 0.000
M21 Other acquired deformities of limbs
0.850 0.150 0.000
G56.1 Other lesions of median nerve
0.848 0.152 0.000
M32 Systemic lupus erythematosus
0.846 0.154 0.000
D69.4 Other primary thrombocytopenia
0.845 0.155 0.000
N05.1 Focal and segmental glomerular lesions
0.845 0.155 0.000
L93 Lupus erythematosus
0.845 0.155 0.000
R30 Pain associated with micturition
0.000 0.159 0.841
M80-M85 Disorders of bone density and structure
0.839 0.161 0.000
M23.4 Loose body in knee
0.839 0.161 0.000
E14.6 With other specified complications
0.838 0.162 0.000
G00 Bacterial meningitis, not elsewhere classified
0.838 0.162 0.000
E03.8 Other specified hypothyroidism
0.838 0.162 0.000
M60 Myositis
0.838 0.162 0.000
M89 Other disorders of bone
0.837 0.163 0.000
E89.3 Postprocedural hypopituitarism
0.836 0.164 0.000
R30.0 Dysuria
0.000 0.164 0.836
H04.8 Other disorders of lachrymal system
0.833 0.167 0.000
B25.9 Cytomegaloviral disease, unspecified
0.833 0.167 0.000
G70-G73 Diseases of myoneural junction and muscle
0.831 0.169 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.830 0.170 0.000
M10.9 Gout, unspecified
0.830 0.170 0.000
G11 Hereditary ataxia
0.830 0.170 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.830 0.170 0.000
H02.2 Lagophthalmos
0.829 0.171 0.000
M86.6 Other chronic osteomyelitis
0.828 0.172 0.000
M14 Arthropathies in other diseases classified elsewhere
0.827 0.173 0.000
C81.1 Nodular sclerosis
0.826 0.174 0.000
Y42.2 Antithyroid drugs
0.825 0.175 0.000
M13 Other arthritis
0.824 0.176 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.823 0.177 0.000
E14.1 With ketoacidosis
0.823 0.177 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.822 0.178 0.000
L94 Other localised connective tissue disorders
0.822 0.178 0.000
R63.4 Abnormal weight loss
0.822 0.178 0.000
Y43.3 Other antineoplastic drugs
0.821 0.179 0.000
B02 Zoster [herpes zoster]
0.820 0.180 0.000
E14.2 Withrenal complications
0.820 0.180 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.818 0.182 0.000
W05 Fall involving wheelchair
0.817 0.183 0.000
H53 Visual disturbances
0.816 0.184 0.000
M67 Other disorders of synovium and tendon
0.815 0.185 0.000
I70 Atherosclerosis
0.815 0.185 0.000
V40-V49 Car occupant injured in transport accident
0.815 0.185 0.000
H90-H95 Other disorders of ear
0.815 0.185 0.000
M86.1 Other acute osteomyelitis
0.812 0.188 0.000
M17.0 Primary gonarthrosis, bilateral
0.811 0.189 0.000
M86.8 Other osteomyelitis
0.810 0.190 0.000
E11.7 With multiple complications
0.809 0.191 0.000
H30 Chorioretinal inflammation
0.809 0.191 0.000
H61 Other disorders of external ear
0.809 0.191 0.000
L03.9 Cellulitis, unspecified
0.808 0.192 0.000
L81 Other disorders of pigmentation
0.808 0.192 0.000
N04.2 Diffuse membranous glomerulonephritis
0.807 0.193 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.806 0.194 0.000
E14.5 With peripheral circulatory complications
0.806 0.194 0.000
N18.2 Chronic kidney disease, stage 2
0.805 0.195 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.804 0.196 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.803 0.196 0.000
J90-J94 Other diseases of pleura
0.803 0.197 0.000
H90 Conductive and sensorineural hearing loss
0.803 0.197 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.803 0.197 0.000
E22 Hyperfunction of pituitary gland
0.803 0.197 0.000
H02.1 Ectropion of eyelid
0.803 0.197 0.000
D52 Folate deficiency anaemia
0.802 0.198 0.000
N03 Chronic nephritic syndrome
0.802 0.198 0.000
M62.8 Other specified disorders of muscle
0.802 0.198 0.000
E78.1 Pure hyperglyceridaemia
0.802 0.198 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.802 0.198 0.000
C84.5 Other and unspecified T-cell lymphomas
0.800 0.200 0.000
D53 Other nutritional anaemias
0.800 0.200 0.000
M80 Osteoporosis with pathological fracture
0.799 0.200 0.000
J45.0 Predominantly allergic asthma
0.799 0.201 0.000
Q60-Q64 Congenital malformations of the urinary system
0.798 0.202 0.000
C91.5 Adult T-cell leukaemia
0.797 0.203 0.000
J43 Emphysema
0.796 0.204 0.000
W50-W64 Exposure to animate mechanical forces
0.796 0.204 0.000
R39 Other symptoms and signs involving the urinary system
0.000 0.207 0.793
Y54.4 Loop [high-ceiling] diuretics
0.793 0.207 0.000
M33 Dermatopolymyositis
0.792 0.208 0.000
E10.7 With multiple complications
0.792 0.208 0.000
M23.8 Other internal derangements of knee
0.792 0.208 0.000
L50 Urticaria
0.791 0.209 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.791 0.209 0.000
H43.8 Other disorders of vitreous body
0.790 0.210 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.789 0.211 0.000
M34 Systemic sclerosis
0.789 0.211 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.788 0.212 0.000
D55-D59 Haemolytic anaemias
0.788 0.212 0.000
G31.8 Other specified degenerative diseases of nervous system
0.787 0.213 0.000
D50.1 Sideropenic dysphagia
0.787 0.213 0.000
J60-J70 Lung diseases due to external agents
0.786 0.214 0.000
M15.2 Bouchard's nodes (with arthropathy)
0.786 0.214 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.785 0.215 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.785 0.215 0.000
E06.9 Thyroiditis, unspecified
0.785 0.215 0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.784 0.216 0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system
0.000 0.217 0.783
E31 Polyglandular dysfunction
0.783 0.217 0.000
E11.2 With renal complications
0.783 0.217 0.000
C91.0 Acute lymphoblastic leukaemia
0.782 0.218 0.000
C83.1 Small cleaved cell (diffuse)
0.782 0.218 0.000
E23.2 Diabetes insipidus
0.782 0.218 0.000
E78.4 Other hyperlipidaemia
0.782 0.218 0.000
M00 Pyogenic arthritis
0.781 0.219 0.000
K72.0 Acute and subacute hepatic failure
0.781 0.219 0.000
G11.9 Hereditary ataxia, unspecified
0.781 0.219 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.781 0.219 0.000
H02.6 Xanthelasma of eyelid
0.781 0.219 0.000
K72.9 Hepatic failure, unspecified
0.780 0.220 0.000
M21.0 Valgus deformity, not elsewhere classified
0.780 0.220 0.000
M13.0 Polyarthritis, unspecified
0.779 0.221 0.000
M86.96 Osteomyelitis, unspecified (Lower leg)
0.778 0.222 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.777 0.223 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.776 0.224 0.000
E70 Disorders of aromatic amino-acid metabolism
0.775 0.225 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.774 0.226 0.000
E87.7 Fluid overload
0.774 0.226 0.000
C92.1 Chronic myeloid leukaemia
0.772 0.228 0.000
W13 Fall from, out of or through building or structure
0.772 0.228 0.000
G56.4 Causalgia
0.772 0.228 0.000
H34.2 Other retinal artery occlusions
0.772 0.228 0.000
H60 Otitis externa
0.772 0.228 0.000
E88 Other metabolic disorders
0.771 0.229 0.000
H31 Other disorders of choroid
0.770 0.230 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.770 0.230 0.000
D68.0 Von Willebrand's disease
0.770 0.230 0.000
K90.8 Other intestinal malabsorption
0.770 0.230 0.000
X60-X84 Intentional self-harm
0.769 0.231 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.768 0.232 0.000
C91.9 Lymphoid leukaemia, unspecified
0.767 0.232 0.000
D72 Other disorders of white blood cells
0.767 0.233 0.000
M06.4 Inflammatory polyarthropathy
0.766 0.234 0.000
E14.4 With neurological complications
0.766 0.234 0.000
B00.5 Herpesviral ocular disease
0.765 0.235 0.000
M60.9 Myositis, unspecified
0.765 0.235 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.765 0.235 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.764 0.236 0.000
D69.2 Other nonthrombocytopenic purpura
0.763 0.237 0.000
L03.8 Cellulitis of other sites
0.761 0.239 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.761 0.239 0.000
B00.9 Herpesviral infection, unspecified
0.761 0.239 0.000
J45.1 Nonallergic asthma
0.760 0.240 0.000
M06.8 Other specified rheumatoid arthritis
0.760 0.240 0.000
H00 Hordeolum and chalazion
0.380 0.241 0.379
M67.1 Other contracture of tendon (sheath)
0.758 0.242 0.000
Y52 Agents primarily affecting the cardiovascular system
0.758 0.242 0.000
A48 Other bacterial diseases, not elsewhere classified
0.758 0.242 0.000
M35.7 Hypermobility syndrome
0.757 0.243 0.000
B37.4 Candidiasis of other urogenital sites
0.757 0.243 0.000
X10-X19 Contact with heat and hot substances
0.756 0.243 0.000
C95 Leukaemia of unspecified cell type
0.756 0.244 0.000
G50 Disorders of trigeminal nerve
0.756 0.244 0.000
E07.8 Other specified disorders of thyroid
0.756 0.244 0.000
M35.1 Other overlap syndromes
0.756 0.244 0.000
E78.2 Mixed hyperlipidaemia
0.756 0.244 0.000
G51 Facial nerve disorders
0.756 0.244 0.000
H43.9 Disorder of vitreous body, unspecified
0.756 0.244 0.000
G52 Disorders of other cranial nerves
0.756 0.244 0.000
L12 Pemphigoid
0.756 0.244 0.000
I74.8 Embolism and thrombosis of other arteries
0.755 0.244 0.000
H34.1 Central retinal artery occlusion
0.755 0.245 0.000
N02 Recurrent and persistent haematuria
0.754 0.246 0.000
H61.0 Perichondritis of external ear
0.753 0.247 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.752 0.248 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.751 0.249 0.000
C83.7 Burkitt's tumour
0.751 0.249 0.000
L40-L45 Papulosquamous disorders
0.748 0.249 0.002
E73 Lactose intolerance
0.750 0.250 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.749 0.251 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.748 0.252 0.000
W75-W84 Other accidental threats to breathing
0.748 0.252 0.000
M66 Spontaneous rupture of synovium and tendon
0.747 0.253 0.000
H25-H28 Disorders of lens
0.746 0.254 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.746 0.254 0.000
B37.7 Candidal septicaemia
0.746 0.254 0.000
G00.1 Pneumococcal meningitis
0.746 0.254 0.000
M22 Disorders of patella
0.744 0.256 0.000
M10.0 Idiopathic gout
0.743 0.256 0.000
A15-A19 Tuberculosis
0.743 0.257 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.743 0.257 0.000
H34.9 Retinal vascular occlusion, unspecified
0.742 0.258 0.000
D86.3 Sarcoidosis of skin
0.742 0.258 0.000
G00.9 Bacterial meningitis, unspecified
0.742 0.258 0.000
E28 Ovarian dysfunction
0.741 0.259 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.741 0.259 0.000
D82 Immunodeficiency associated with other major defects
0.741 0.259 0.000
E87.0 Hyperosmolality and hypernatraemia
0.741 0.259 0.000
N18.5 Chronic kidney disease, stage 5
0.741 0.259 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.741 0.259 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.740 0.260 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.739 0.261 0.000
H05.2 Exophthalmic conditions
0.739 0.261 0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]
0.739 0.261 0.000
Y48 Anaesthetics and therapeutic gases
0.739 0.261 0.000
H02.3 Blepharochalasis
0.738 0.262 0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.738 0.262 0.000
N05.7 Diffuse crescentic glomerulonephritis
0.738 0.262 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.738 0.262 0.000
L95.9 Vasculitis limited to skin, unspecified
0.738 0.262 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.737 0.263 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.737 0.263 0.000
M24.9 Joint derangement, unspecified
0.737 0.263 0.000
I00-I02 Acute rheumatic fever
0.737 0.263 0.000
W18 Other fall on same level
0.736 0.264 0.000
E78.6 Lipoprotein deficiency
0.736 0.264 0.000
D64.8 Other specified anaemias
0.735 0.264 0.000
M17.5 Other secondary gonarthrosis
0.735 0.265 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.735 0.265 0.000
H54 Blindness and low vision
0.735 0.265 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.735 0.265 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.734 0.266 0.000
B34 Viral infection of unspecified site
0.734 0.266 0.000
Q44.6 Cystic disease of liver
0.733 0.267 0.000
J90 Pleural effusion, not elsewhere classified
0.733 0.267 0.000
D83 Common variable immunodeficiency
0.733 0.267 0.000
A31 Infection due to other mycobacteria
0.732 0.268 0.000
L80 Vitiligo
0.732 0.268 0.000
V90-V94 Water transport accidents
0.732 0.268 0.000
Q35-Q37 Cleft lip and cleft palate
0.732 0.268 0.000
I77.2 Rupture of artery
0.732 0.268 0.000
K75.0 Abscess of liver
0.731 0.269 0.000
N18.1 Chronic kidney disease, stage 1
0.731 0.269 0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)
0.730 0.270 0.000
E11.0 With coma
0.730 0.270 0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)
0.730 0.270 0.000
G56.9 Mononeuropathy of upper limb, unspecified
0.730 0.270 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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