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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3094636
log Bayes Factor = 60.4038
Chromosome 6   position 30,211,755  (GRCh37) Explore rs3094636 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.001 0.999
E03 Other hypothyroidism
0.000 0.003 0.997
E03.9 Hypothyroidism, unspecified
0.000 0.005 0.995
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.006 0.994
E14 Unspecified diabetes mellitus
0.000 0.007 0.993
M06.9 Rheumatoid arthritis, unspecified
0.000 0.007 0.993
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.010 0.990
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.010 0.990
E14.3 With ophthalmic complications
0.000 0.018 0.982
E10.1 With ketoacidosis
0.000 0.027 0.973
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.034 0.966
E10.3 With ophthalmic complications
0.000 0.051 0.949
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.058 0.942
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.086 0.914
E10.0 With coma
0.000 0.103 0.897
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.104 0.896
E13 Other specified diabetes mellitus
0.000 0.120 0.880
E14.8 With unspecified complications
0.000 0.143 0.857
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.144 0.856
E14.6 With other specified complications
0.000 0.163 0.837
E10.4 With neurological complications
0.000 0.164 0.836
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.164 0.836
E07 Other disorders of thyroid
0.000 0.171 0.829
E03.8 Other specified hypothyroidism
0.000 0.173 0.827
E05.8 Other thyrotoxicosis
0.000 0.190 0.810
E10.6 With other specified complications
0.000 0.200 0.800
E13.9 Without complications
0.000 0.210 0.789
E10.5 With peripheral circulatory complications
0.000 0.211 0.789
E10.7 With multiple complications
0.000 0.218 0.782
E14.4 With neurological complications
0.000 0.219 0.781
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.225 0.775
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.244 0.756
E14.2 Withrenal complications
0.000 0.256 0.744
E10.8 With unspecified complications
0.000 0.256 0.744
E14.1 With ketoacidosis
0.000 0.262 0.738
E07.9 Disorder of thyroid, unspecified
0.000 0.268 0.732
E16 Other disorders of pancreatic internal secretion
0.000 0.278 0.722
E10.2 With renal complications
0.000 0.280 0.720
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.285 0.715
E03.4 Atrophy of thyroid (acquired)
0.000 0.285 0.715
E03.3 Postinfectious hypothyroidism
0.000 0.285 0.715
E14.5 With peripheral circulatory complications
0.000 0.286 0.714
E14.7 With multiple complications
0.000 0.288 0.712
E14.0 With coma
0.000 0.288 0.712
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.294 0.705
E03.1 Congenital hypothyroidism without goitre
0.000 0.302 0.698
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.314 0.686
E50-E64 Other nutritional deficiencies
0.000 0.319 0.681
M06 Other rheumatoid arthritis
0.000 0.323 0.677
E13.3 With ophthalmic complications
0.000 0.358 0.642
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.364 0.636
E13.8 With unspecified complications
0.000 0.369 0.631
E13.7 With multiple complications
0.000 0.369 0.631
E13.6 With other specified complications
0.000 0.369 0.631
E13.5 With peripheral circulatory complications
0.000 0.369 0.631
E13.4 With neurological complications
0.000 0.369 0.631
E13.2 With renal complications
0.000 0.369 0.631
E13.1 With ketoacidosis
0.000 0.369 0.631
E13.0 With coma
0.000 0.369 0.631
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.380 0.620
E16.2 Hypoglycaemia, unspecified
0.000 0.394 0.606
E15 Nondiabetic hypoglycaemic coma
0.000 0.401 0.599
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.402 0.598
E07.1 Dyshormogenetic goitre
0.000 0.406 0.594
E07.0 Hypersecretion of calcitonin
0.000 0.406 0.594
M06.4 Inflammatory polyarthropathy
0.000 0.406 0.594
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.410 0.590
E40-E46 Malnutrition
0.000 0.447 0.553
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.447 0.553
M06.3 Rheumatoid nodule
0.000 0.452 0.548
E07.8 Other specified disorders of thyroid
0.000 0.467 0.533
E56 Other vitamin deficiencies
0.000 0.478 0.522
E61 Deficiency of other nutrient elements
0.000 0.479 0.521
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.482 0.518
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.482 0.518
E16.4 Abnormal secretion of gastrin
0.000 0.482 0.518
E16.3 Increased secretion of glucagon
0.000 0.482 0.518
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E16.1 Other hypoglycaemia
0.000 0.499 0.501
E54 Ascorbic acid deficiency
0.000 0.501 0.499
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.512 0.488
E50 Vitamin A deficiency
0.000 0.512 0.488
E60 Dietary zinc deficiency
0.000 0.512 0.488
E59 Dietary selenium deficiency
0.000 0.512 0.488
E52 Niacin deficiency [pellagra]
0.000 0.512 0.488
M06.2 Rheumatoid bursitis
0.000 0.515 0.485
M06.1 Adult-onset Still's disease
0.000 0.515 0.485
E55 Vitamin D deficiency
0.000 0.523 0.477
E53 Deficiency of other B group vitamins
0.000 0.530 0.470
E51 Thiamine deficiency
0.000 0.537 0.463
M06.0 Seronegative rheumatoid arthritis
0.000 0.543 0.457
E63 Other nutritional deficiencies
0.000 0.543 0.457
E58 Dietary calcium deficiency
0.000 0.548 0.452
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.548 0.452
M06.8 Other specified rheumatoid arthritis
0.000 0.549 0.451
M06.34 Rheumatoid nodule (Hand)
0.000 0.555 0.445
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.568 0.432
E61.1 Iron deficiency
0.000 0.572 0.428
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.574 0.426
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.574 0.426
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.574 0.426
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.574 0.426
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.574 0.426
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.574 0.426
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.574 0.426
K90 Intestinal malabsorption
0.000 0.581 0.419
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.584 0.416
G35 Multiple sclerosis
0.412 0.588 0.000
E56.1 Deficiency of vitamin K
0.000 0.592 0.408
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.603 0.397
E45 Retarded development following protein-energy malnutrition
0.000 0.603 0.397
E43 Unspecified severe protein-energy malnutrition
0.000 0.603 0.397
E42 Marasmic kwashiorkor
0.000 0.603 0.397
E41 Nutritional marasmus
0.000 0.603 0.397
E40 Kwashiorkor
0.000 0.603 0.397
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.607 0.393
M06.38 Rheumatoid nodule (Other)
0.000 0.607 0.393
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.607 0.393
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.607 0.393
M06.33 Rheumatoid nodule (Forearm)
0.000 0.607 0.393
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.607 0.393
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.615 0.384
E20-E35 Disorders of other endocrine glands
0.000 0.624 0.376
E56.9 Vitamin deficiency, unspecified
0.000 0.625 0.374
E56.8 Deficiency of other vitamins
0.000 0.625 0.374
E56.0 Deficiency of vitamin E
0.000 0.625 0.374
E61.9 Deficiency of nutrient element, unspecified
0.000 0.626 0.374
E61.8 Deficiency of other specified nutrient elements
0.000 0.626 0.374
E61.7 Deficiency of multiple nutrient elements
0.000 0.626 0.374
E61.6 Vanadium deficiency
0.000 0.626 0.374
E61.5 Molybdenum deficiency
0.000 0.626 0.374
E61.4 Chromium deficiency
0.000 0.626 0.374
E61.3 Manganese deficiency
0.000 0.626 0.374
E61.0 Copper deficiency
0.000 0.626 0.374
E06 Thyroiditis
0.000 0.626 0.373
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.646 0.354
E50.9 Vitamin A deficiency, unspecified
0.000 0.650 0.350
E50.8 Other manifestations of vitamin A deficiency
0.000 0.650 0.350
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.650 0.350
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.650 0.350
E50.5 Vitamin A deficiency with night blindness
0.000 0.650 0.350
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.650 0.350
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.650 0.350
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.650 0.350
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.650 0.350
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.650 0.350
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.650 0.350
E64.8 Sequelae of other nutritional deficiencies
0.000 0.650 0.350
E64.3 Sequelae of rickets
0.000 0.650 0.350
E64.2 Sequelae of vitamin C deficiency
0.000 0.650 0.350
E64.1 Sequelae of vitamin A deficiency
0.000 0.650 0.350
E64.0 Sequelae of protein-energy malnutrition
0.000 0.650 0.350
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.652 0.348
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.652 0.348
M06.18 Adult-onset Still's disease (Other)
0.000 0.652 0.348
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.652 0.348
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.652 0.348
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.652 0.348
M06.14 Adult-onset Still's disease (Hand)
0.000 0.652 0.348
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.652 0.348
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.652 0.348
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.652 0.348
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.652 0.348
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.652 0.348
M06.28 Rheumatoid bursitis (Other)
0.000 0.652 0.348
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.652 0.348
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.652 0.348
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.652 0.348
M06.24 Rheumatoid bursitis (Hand)
0.000 0.652 0.348
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.652 0.348
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.652 0.348
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.652 0.348
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.652 0.348
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.655 0.345
E55.0 Rickets, active
0.000 0.658 0.342
E61.2 Magnesium deficiency
0.000 0.660 0.340
K90.8 Other intestinal malabsorption
0.000 0.660 0.340
E53.1 Pyridoxine deficiency
0.000 0.663 0.337
E53.0 Riboflavin deficiency
0.000 0.663 0.337
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.666 0.334
E51.9 Thiamine deficiency, unspecified
0.000 0.668 0.332
E51.8 Other manifestations of thiamine deficiency
0.000 0.668 0.332
E51.1 Beriberi
0.000 0.668 0.332
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.668 0.332
E55.9 Vitamin D deficiency, unspecified
0.000 0.669 0.331
E53.9 Vitamin B deficiency, unspecified
0.000 0.671 0.329
E53.8 Deficiency of other specified B group vitamins
0.000 0.672 0.328
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.672 0.328
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.672 0.328
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.672 0.328
E63.8 Other specified nutritional deficiencies
0.000 0.672 0.328
E63.1 Imbalance of constituents of food intake
0.000 0.672 0.328
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.672 0.328
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.676 0.323
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.676 0.323
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.676 0.323
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.676 0.323
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.676 0.323
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.676 0.323
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.676 0.323
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.676 0.323
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.676 0.323
E65-E68 Obesity and other hyperalimentation
0.000 0.684 0.316
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.691 0.309
E51.2 Wernicke's encephalopathy
0.000 0.693 0.307
E24 Cushing's syndrome
0.000 0.694 0.306
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.698 0.301
K90.3 Pancreatic steatorrhoea
0.000 0.700 0.300
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.700 0.300
K90.1 Tropical sprue
0.000 0.700 0.300
E27 Other disorders of adrenal gland
0.000 0.702 0.298
E63.9 Nutritional deficiency, unspecified
0.000 0.704 0.296
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.001 0.709 0.290
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.711 0.289
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.711 0.289
G35-G37 Demyelinating diseases of the central nervous system
0.288 0.712 0.000
E44.1 Mild protein-energy malnutrition
0.000 0.715 0.284
E44.0 Moderate protein-energy malnutrition
0.000 0.715 0.284
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.715 0.284
E22 Hyperfunction of pituitary gland
0.000 0.718 0.282
E31 Polyglandular dysfunction
0.000 0.718 0.282
E14.9 Without complications
0.000 0.720 0.280
E27.1 Primary adrenocortical insufficiency
0.000 0.724 0.276
E06.1 Subacute thyroiditis
0.000 0.727 0.273
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.728 0.272
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.730 0.270
E32 Diseases of thymus
0.000 0.730 0.270
E30 Disorders of puberty, not elsewhere classified
0.000 0.730 0.270
E24.2 Drug-induced Cushing's syndrome
0.000 0.730 0.270
E06.4 Drug-induced thyroiditis
0.000 0.732 0.268
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.732 0.268
E06.0 Acute thyroiditis
0.000 0.732 0.268
E20 Hypoparathyroidism
0.000 0.732 0.268
E34 Other endocrine disorders
0.000 0.737 0.263
E06.5 Other chronic thyroiditis
0.000 0.739 0.260
E29 Testicular dysfunction
0.000 0.740 0.260
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.744 0.256
G37 Other demyelinating diseases of central nervous system
0.253 0.747 0.000
E28 Ovarian dysfunction
0.000 0.749 0.251
E25 Adrenogenital disorders
0.000 0.751 0.249
K90.9 Intestinal malabsorption, unspecified
0.000 0.752 0.248
E46 Unspecified protein-energy malnutrition
0.000 0.763 0.237
E27.9 Disorder of adrenal gland, unspecified
0.000 0.765 0.235
G37.9 Demyelinating disease of central nervous system, unspecified
0.235 0.765 0.000
E24.0 Pituitary-dependent Cushing's disease
0.000 0.772 0.228
E67 Other hyperalimentation
0.000 0.773 0.226
E68 Sequelae of hyperalimentation
0.000 0.773 0.226
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.773 0.227
G36 Other acute disseminated demyelination
0.222 0.778 0.000
E24.8 Other Cushing's syndrome
0.000 0.780 0.220
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.780 0.220
E24.3 Ectopic ACTH syndrome
0.000 0.780 0.220
E24.1 Nelson's syndrome
0.000 0.780 0.220
E31.0 Autoimmune polyglandular failure
0.000 0.786 0.214
E27.5 Adrenomedullary hyperfunction
0.000 0.786 0.214
E27.0 Other adrenocortical overactivity
0.000 0.786 0.214
E34.9 Endocrine disorder, unspecified
0.000 0.788 0.212
E20.9 Hypoparathyroidism, unspecified
0.000 0.789 0.210
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.795 0.204
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.797 0.203
E22.8 Other hyperfunction of pituitary gland
0.000 0.797 0.203
E31.9 Polyglandular dysfunction, unspecified
0.000 0.798 0.202
E31.8 Other polyglandular dysfunction
0.000 0.798 0.202
E31.1 Polyglandular hyperfunction
0.000 0.798 0.202
E30.9 Disorder of puberty, unspecified
0.000 0.806 0.193
E30.8 Other disorders of puberty
0.000 0.806 0.193
E30.1 Precocious puberty
0.000 0.806 0.193
E30.0 Delayed puberty
0.000 0.806 0.193
E32.9 Disease of thymus, unspecified
0.000 0.806 0.193
E32.8 Other diseases of thymus
0.000 0.806 0.193
E32.1 Abscess of thymus
0.000 0.806 0.193
E32.0 Persistent hyperplasia of thymus
0.000 0.806 0.193
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.806 0.193
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.806 0.193
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.806 0.193
E34.3 Short stature, not elsewhere classified
0.000 0.807 0.193
E20.8 Other hypoparathyroidism
0.000 0.808 0.192
E20.0 Idiopathic hypoparathyroidism
0.000 0.808 0.192
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.190 0.810 0.000
E34.5 Androgen resistance syndrome
0.000 0.811 0.189
E34.4 Constitutional tall stature
0.000 0.811 0.189
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.811 0.189
E34.1 Other hypersecretion of intestinal hormones
0.000 0.811 0.189
E29.9 Testicular dysfunction, unspecified
0.000 0.813 0.187
E29.8 Other testicular dysfunction
0.000 0.813 0.187
E29.0 Testicular hyperfunction
0.000 0.813 0.187
E22.1 Hyperprolactinaemia
0.000 0.814 0.186
E26 Hyperaldosteronism
0.000 0.816 0.183
G37.5 Concentric sclerosis [Balo]
0.182 0.818 0.000
G37.4 Subacute necrotising myelitis
0.182 0.818 0.000
G37.2 Central pontine myelinolysis
0.182 0.818 0.000
G37.1 Central demyelination of corpus callosum
0.182 0.818 0.000
G37.0 Diffuse sclerosis
0.182 0.818 0.000
E28.9 Ovarian dysfunction, unspecified
0.000 0.820 0.180
E28.8 Other ovarian dysfunction
0.000 0.820 0.180
E28.1 Androgen excess
0.000 0.820 0.180
E28.0 Oestrogen excess
0.000 0.820 0.180
E25.9 Adrenogenital disorder, unspecified
0.000 0.821 0.179
E25.8 Other adrenogenital disorders
0.000 0.821 0.179
E29.1 Testicular hypofunction
0.000 0.822 0.177
E24.9 Cushing's syndrome, unspecified
0.000 0.823 0.177
E34.8 Other specified endocrine disorders
0.000 0.824 0.176
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.825 0.175
G36.0 Neuromyelitis optica [Devic]
0.174 0.825 0.000
E28.3 Primary ovarian failure
0.000 0.828 0.172
E28.2 Polycystic ovarian syndrome
0.000 0.829 0.171
E20.1 Pseudohypoparathyroidism
0.000 0.835 0.165
E23 Hypofunction and other disorders of pituitary gland
0.000 0.835 0.165
E83 Disorders of mineral metabolism
0.164 0.835 0.001
E67.8 Other specified hyperalimentation
0.000 0.837 0.162
E67.3 Hypervitaminosis D
0.000 0.837 0.162
E67.2 Megavitamin-B6 syndrome
0.000 0.837 0.162
E67.1 Hypercarotenaemia
0.000 0.837 0.162
E67.0 Hypervitaminosis A
0.000 0.837 0.162
E06.9 Thyroiditis, unspecified
0.001 0.838 0.161
G36.9 Acute disseminated demyelination, unspecified
0.159 0.841 0.000
G36.8 Other specified acute disseminated demyelination
0.159 0.841 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.159 0.841 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.842 0.158
E34.0 Carcinoid syndrome
0.000 0.843 0.157
E06.3 Autoimmune thyroiditis
0.000 0.846 0.153
E27.8 Other specified disorders of adrenal gland
0.000 0.853 0.147
G37.8 Other specified demyelinating diseases of central nervous system
0.144 0.855 0.000
E21.3 Hyperparathyroidism, unspecified
0.000 0.860 0.140
E23.2 Diabetes insipidus
0.000 0.860 0.140
E83.3 Disorders of phosphorus metabolism
0.139 0.860 0.000
E21.4 Other specified disorders of parathyroid gland
0.000 0.867 0.133
E27.2 Addisonian crisis
0.000 0.868 0.132
E26.8 Other hyperaldosteronism
0.000 0.868 0.131
E26.1 Secondary hyperaldosteronism
0.000 0.868 0.131
E65 Localised adiposity
0.001 0.871 0.128
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.873 0.126
E83.9 Disorder of mineral metabolism, unspecified
0.125 0.874 0.001
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.882 0.118
E23.1 Drug-induced hypopituitarism
0.000 0.882 0.118
E83.8 Other disorders of mineral metabolism
0.117 0.882 0.001
E83.2 Disorders of zinc metabolism
0.117 0.882 0.001
E83.0 Disorders of copper metabolism
0.117 0.882 0.001
E22.0 Acromegaly and pituitary gigantism
0.000 0.882 0.117
E21.2 Other hyperparathyroidism
0.000 0.882 0.117
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.886 0.113
E26.9 Hyperaldosteronism, unspecified
0.001 0.888 0.112
M05-M14 Inflammatory polyarthropathies
0.000 0.896 0.103
E04 Other non-toxic goitre
0.000 0.899 0.101
M12 Other specific arthropathies
0.000 0.908 0.092
M05 Seropositive rheumatoid arthritis
0.000 0.911 0.089
E23.6 Other disorders of pituitary gland
0.000 0.911 0.089
E66 Obesity
0.000 0.916 0.084
E26.0 Primary hyperaldosteronism
0.001 0.916 0.083
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.917 0.083
E23.7 Disorder of pituitary gland, unspecified
0.000 0.921 0.079
M12.3 Palindromic rheumatism
0.000 0.923 0.077
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.077 0.923 0.000
O32.1 Maternal care for breech presentation
0.000 0.924 0.076
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.076 0.924 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.075 0.925 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.926 0.074
E04.8 Other specified non-toxic goitre
0.000 0.927 0.073
E66.8 Other obesity
0.000 0.927 0.073
E23.0 Hypopituitarism
0.000 0.928 0.072
M12.2 Villonodular synovitis (pigmented)
0.000 0.929 0.071
M12.8 Other specific arthropathies, not elsewhere classified
0.000 0.929 0.071
T83.0 Mechanical complication of urinary (indwelling) catheter
0.071 0.929 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.929 0.071
M08 Juvenile arthritis
0.000 0.930 0.070
M12.5 Traumatic arthropathy
0.000 0.931 0.069
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.931 0.069
M12.39 Palindromic rheumatism (Site unspecified)
0.000 0.931 0.068
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.933 0.067
M14 Arthropathies in other diseases classified elsewhere
0.000 0.934 0.066
M05.8 Other seropositive rheumatoid arthritis
0.000 0.934 0.066
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.066 0.934 0.000
M12.4 Intermittent hydrarthrosis
0.000 0.934 0.066
M12.1 Kaschin-Beck disease
0.000 0.934 0.066
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.000 0.934 0.066
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.935 0.065
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.065 0.935 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.936 0.064
M05.0 Felty's syndrome
0.000 0.936 0.064
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.936 0.064
E04.0 Non-toxic diffuse goitre
0.000 0.939 0.061
E66.1 Drug-induced obesity
0.000 0.939 0.060
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.940 0.060
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.940 0.060
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.940 0.060
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.059 0.941 0.000
M12.26 Villonodular synovitis (pigmented) (Lower leg)
0.000 0.941 0.059
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.058 0.942 0.000
K75.4 Autoimmune hepatitis
0.000 0.942 0.058
T83.3 Mechanical complication of intra-uterine contraceptive device
0.057 0.943 0.000
M05.1 Rheumatoid lung disease
0.000 0.943 0.056
M11 Other crystal arthropathies
0.000 0.944 0.056
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.944 0.056
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.944 0.056
M12.88 Other specific arthropathies, not elsewhere classified (Other)
0.000 0.944 0.056
M12.38 Palindromic rheumatism (Other)
0.000 0.944 0.055
M12.37 Palindromic rheumatism (Ankle and foot)
0.000 0.944 0.055
M12.36 Palindromic rheumatism (Lower leg)
0.000 0.944 0.055
M12.35 Palindromic rheumatism (Pelvic region and thigh)
0.000 0.944 0.055
M12.34 Palindromic rheumatism (Hand)
0.000 0.944 0.055
M12.33 Palindromic rheumatism (Forearm)
0.000 0.944 0.055
M12.32 Palindromic rheumatism (Upper arm)
0.000 0.944 0.055
M12.31 Palindromic rheumatism (Shoulder region)
0.000 0.944 0.055
M05.2 Rheumatoid vasculitis
0.000 0.945 0.055
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.000 0.946 0.053
M09.2 Juvenile arthritis in ulcerative colitis
0.000 0.946 0.053
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.000 0.946 0.053
M09.0 Juvenile arthritis in psoriasis
0.000 0.946 0.053
M12.57 Traumatic arthropathy (Ankle and foot)
0.000 0.947 0.052
M12.30 Palindromic rheumatism (Multiple sites)
0.000 0.948 0.052
M12.29 Villonodular synovitis (pigmented) (Site unspecified)
0.000 0.949 0.051
M12.28 Villonodular synovitis (pigmented) (Other)
0.000 0.949 0.051
M12.27 Villonodular synovitis (pigmented) (Ankle and foot)
0.000 0.949 0.051
M12.25 Villonodular synovitis (pigmented) (Pelvic region and thigh)
0.000 0.949 0.051
M12.23 Villonodular synovitis (pigmented) (Forearm)
0.000 0.949 0.051
M12.22 Villonodular synovitis (pigmented) (Upper arm)
0.000 0.949 0.051
M12.21 Villonodular synovitis (pigmented) (Shoulder region)
0.000 0.949 0.051
M12.20 Villonodular synovitis (pigmented) (Multiple sites)
0.000 0.949 0.051
M10 Gout
0.000 0.949 0.051
M12.89 Other specific arthropathies, not elsewhere classified (Site unspecified)
0.000 0.949 0.051
M12.87 Other specific arthropathies, not elsewhere classified (Ankle and foot)
0.000 0.949 0.051
M12.86 Other specific arthropathies, not elsewhere classified (Lower leg)
0.000 0.949 0.051
M12.85 Other specific arthropathies, not elsewhere classified (Pelvic region and thigh)
0.000 0.949 0.051
M12.84 Other specific arthropathies, not elsewhere classified (Hand)
0.000 0.949 0.051
M12.83 Other specific arthropathies, not elsewhere classified (Forearm)
0.000 0.949 0.051
M12.82 Other specific arthropathies, not elsewhere classified (Upper arm)
0.000 0.949 0.051
M12.81 Other specific arthropathies, not elsewhere classified (Shoulder region)
0.000 0.949 0.051
M12.80 Other specific arthropathies, not elsewhere classified (Multiple sites)
0.000 0.949 0.051
M08.9 Juvenile arthritis, unspecified
0.000 0.949 0.050
M08.8 Other juvenile arthritis
0.000 0.949 0.050
M08.4 Pauciarticular juvenile arthritis
0.000 0.949 0.050
M08.3 Juvenile polyarthritis (seronegative)
0.000 0.949 0.050
M08.2 Juvenile arthritis with systemic onset
0.000 0.949 0.050
M08.1 Juvenile ankylosing spondylitis
0.000 0.949 0.050
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.000 0.950 0.050
E04.9 Non-toxic goitre, unspecified
0.000 0.950 0.050
M12.59 Traumatic arthropathy (Site unspecified)
0.000 0.950 0.050
M12.58 Traumatic arthropathy (Other)
0.000 0.950 0.050
M12.56 Traumatic arthropathy (Lower leg)
0.000 0.950 0.050
M12.55 Traumatic arthropathy (Pelvic region and thigh)
0.000 0.950 0.050
M12.54 Traumatic arthropathy (Hand)
0.000 0.950 0.050
M12.53 Traumatic arthropathy (Forearm)
0.000 0.950 0.050
M12.52 Traumatic arthropathy (Upper arm)
0.000 0.950 0.050
M12.51 Traumatic arthropathy (Shoulder region)
0.000 0.950 0.050
M12.50 Traumatic arthropathy (Multiple sites)
0.000 0.950 0.050
M14.2 Diabetic arthropathy
0.000 0.951 0.048
M14.8 Arthropathies in other specified diseases classified elsewhere
0.000 0.952 0.048
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.952 0.048
M14.4 Arthropathy in amyloidosis
0.000 0.952 0.048
M14.3 Lipoid dermatoarthritis
0.000 0.952 0.048
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.952 0.048
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.952 0.048
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.000 0.952 0.048
M05.88 Other seropositive rheumatoid arthritis (Other)
0.000 0.952 0.048
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.000 0.952 0.048
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.000 0.952 0.048
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.000 0.952 0.048
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.000 0.952 0.048
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.000 0.952 0.048
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.000 0.952 0.048
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.000 0.952 0.048
M12.09 Chronic postrheumatic arthropathy [Jaccoud] (Site unspecified)
0.000 0.952 0.047
M12.08 Chronic postrheumatic arthropathy [Jaccoud] (Other)
0.000 0.952 0.047
M12.07 Chronic postrheumatic arthropathy [Jaccoud] (Ankle and foot)
0.000 0.952 0.047
M12.06 Chronic postrheumatic arthropathy [Jaccoud] (Lower leg)
0.000 0.952 0.047
M12.05 Chronic postrheumatic arthropathy [Jaccoud] (Pelvic region and thigh)
0.000 0.952 0.047
M12.04 Chronic postrheumatic arthropathy [Jaccoud] (Hand)
0.000 0.952 0.047
M12.03 Chronic postrheumatic arthropathy [Jaccoud] (Forearm)
0.000 0.952 0.047
M12.02 Chronic postrheumatic arthropathy [Jaccoud] (Upper arm)
0.000 0.952 0.047
M12.01 Chronic postrheumatic arthropathy [Jaccoud] (Shoulder region)
0.000 0.952 0.047

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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