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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2516440
log Bayes Factor = 24.7529
Chromosome 6   position 31,440,497  (GRCh37) Explore rs2516440 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.008 0.992
E10.1 With ketoacidosis
0.000 0.010 0.990
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.011 0.989
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.012 0.988
E10-E14 Diabetes mellitus
0.000 0.014 0.986
H36.0 Diabetic retinopathy
0.000 0.033 0.967
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.035 0.965
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.042 0.958
E00-E07 Disorders of thyroid gland
0.000 0.048 0.952
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.054 0.946
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.054 0.946
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.068 0.932
E10.2 With renal complications
0.000 0.084 0.916
E16 Other disorders of pancreatic internal secretion
0.000 0.087 0.913
E10.0 With coma
0.000 0.092 0.908
E10.4 With neurological complications
0.000 0.101 0.899
E16.2 Hypoglycaemia, unspecified
0.000 0.103 0.897
H36 Retinal disorders in diseases classified elsewhere
0.000 0.107 0.893
E11 Non-insulin-dependent diabetes mellitus
0.000 0.115 0.885
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.124 0.876
E11.3 With ophthalmic complications
0.000 0.138 0.862
E11.1 With ketoacidosis
0.000 0.145 0.855
H30-H36 Disorders of choroid and retina
0.000 0.159 0.841
E04 Other non-toxic goitre
0.000 0.161 0.839
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.162 0.838
E20-E35 Disorders of other endocrine glands
0.000 0.164 0.836
E27 Other disorders of adrenal gland
0.000 0.171 0.829
E27.1 Primary adrenocortical insufficiency
0.000 0.172 0.828
E10.5 With peripheral circulatory complications
0.000 0.183 0.817
E14 Unspecified diabetes mellitus
0.000 0.192 0.808
H33 Retinal detachments and breaks
0.000 0.205 0.795
E04.9 Non-toxic goitre, unspecified
0.000 0.207 0.793
M06 Other rheumatoid arthritis
0.000 0.223 0.777
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.223 0.777
E10.6 With other specified complications
0.000 0.227 0.773
H33.3 Retinal breaks without detachment
0.000 0.236 0.764
E07 Other disorders of thyroid
0.000 0.237 0.763
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.244 0.756
E10.8 With unspecified complications
0.000 0.245 0.755
E14.3 With ophthalmic complications
0.000 0.248 0.752
H34 Retinal vascular occlusions
0.000 0.248 0.752
E11.8 With unspecified complications
0.000 0.267 0.733
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.273 0.727
E06 Thyroiditis
0.000 0.275 0.725
E04.0 Non-toxic diffuse goitre
0.000 0.278 0.721
E07.8 Other specified disorders of thyroid
0.000 0.281 0.719
E10.7 With multiple complications
0.000 0.283 0.717
H35 Other retinal disorders
0.000 0.285 0.715
H33.4 Traction detachment of retina
0.000 0.289 0.711
M06.0 Seronegative rheumatoid arthritis
0.000 0.289 0.711
E22 Hyperfunction of pituitary gland
0.000 0.293 0.707
E12 Malnutrition-related diabetes mellitus
0.000 0.293 0.707
H33.2 Serous retinal detachment
0.000 0.293 0.706
H35.8 Other specified retinal disorders
0.000 0.297 0.703
H34.2 Other retinal artery occlusions
0.000 0.308 0.692
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.309 0.691
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.313 0.687
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.318 0.682
E00 Congenital iodine-deficiency syndrome
0.000 0.318 0.682
E05.5 Thyroid crisis or storm
0.000 0.322 0.678
E05.4 Thyrotoxicosis factitia
0.000 0.322 0.678
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.322 0.678
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.322 0.678
E20 Hypoparathyroidism
0.000 0.324 0.675
E15 Nondiabetic hypoglycaemic coma
0.000 0.332 0.668
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.336 0.664
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.339 0.661
E14.6 With other specified complications
0.000 0.344 0.656
E27.2 Addisonian crisis
0.000 0.345 0.655
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.345 0.654
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.345 0.654
E16.4 Abnormal secretion of gastrin
0.000 0.345 0.654
E16.3 Increased secretion of glucagon
0.000 0.345 0.654
E40-E46 Malnutrition
0.000 0.347 0.653
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.347 0.653
E11.5 With peripheral circulatory complications
0.000 0.358 0.642
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.359 0.641
H35.2 Other proliferative retinopathy
0.000 0.363 0.637
E11.7 With multiple complications
0.000 0.365 0.635
E06.3 Autoimmune thyroiditis
0.000 0.371 0.629
K90 Intestinal malabsorption
0.000 0.375 0.625
E14.1 With ketoacidosis
0.000 0.382 0.618
H30 Chorioretinal inflammation
0.000 0.385 0.615
H34.9 Retinal vascular occlusion, unspecified
0.000 0.385 0.615
M06.3 Rheumatoid nodule
0.000 0.386 0.613
E28 Ovarian dysfunction
0.000 0.393 0.607
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.397 0.603
E04.8 Other specified non-toxic goitre
0.000 0.399 0.601
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.401 0.599
E32 Diseases of thymus
0.000 0.401 0.599
E31 Polyglandular dysfunction
0.000 0.401 0.599
E30 Disorders of puberty, not elsewhere classified
0.000 0.401 0.599
E27.5 Adrenomedullary hyperfunction
0.000 0.405 0.595
E27.0 Other adrenocortical overactivity
0.000 0.405 0.595
H33.1 Retinoschisis and retinal cysts
0.000 0.407 0.593
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.410 0.589
E25 Adrenogenital disorders
0.000 0.411 0.589
E22.0 Acromegaly and pituitary gigantism
0.000 0.412 0.588
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.413 0.587
E14.8 With unspecified complications
0.000 0.413 0.587
M06.4 Inflammatory polyarthropathy
0.000 0.416 0.584
E14.7 With multiple complications
0.000 0.421 0.579
E14.0 With coma
0.000 0.421 0.579
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.421 0.578
H34.8 Other retinal vascular occlusions
0.000 0.435 0.565
E20.9 Hypoparathyroidism, unspecified
0.000 0.439 0.561
M06.2 Rheumatoid bursitis
0.000 0.443 0.557
M06.1 Adult-onset Still's disease
0.000 0.443 0.557
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.445 0.555
E14.2 Withrenal complications
0.000 0.446 0.554
E27.8 Other specified disorders of adrenal gland
0.000 0.449 0.551
E05.9 Thyrotoxicosis, unspecified
0.000 0.449 0.551
E07.1 Dyshormogenetic goitre
0.000 0.453 0.547
E07.0 Hypersecretion of calcitonin
0.000 0.453 0.547
E16.1 Other hypoglycaemia
0.000 0.455 0.545
H34.0 Transient retinal artery occlusion
0.000 0.461 0.539
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.464 0.536
H35.0 Background retinopathy and retinal vascular changes
0.000 0.466 0.534
H31 Other disorders of choroid
0.000 0.469 0.531
H35.5 Hereditary retinal dystrophy
0.000 0.470 0.530
E13 Other specified diabetes mellitus
0.000 0.475 0.524
E06.5 Other chronic thyroiditis
0.000 0.476 0.524
K91.4 Colostomy and enterostomy malfunction
0.000 0.478 0.522
E06.4 Drug-induced thyroiditis
0.000 0.480 0.520
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.480 0.520
E06.0 Acute thyroiditis
0.000 0.480 0.520
K90-K93 Other diseases of the digestive system
0.000 0.484 0.516
H35.1 Retinopathy of prematurity
0.000 0.487 0.513
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.489 0.511
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.490 0.509
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.490 0.509
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.490 0.509
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.490 0.509
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.490 0.509
E11.2 With renal complications
0.000 0.492 0.508
R17 Unspecified jaundice
0.000 0.493 0.507
E24 Cushing's syndrome
0.000 0.493 0.507
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.493 0.507
E22.8 Other hyperfunction of pituitary gland
0.000 0.493 0.507
E12.9 Without complications
0.000 0.493 0.507
E12.8 With unspecified complications
0.000 0.493 0.507
E12.7 With multiple complications
0.000 0.493 0.507
E12.6 With other specified complications
0.000 0.493 0.507
E12.5 With peripheral circulatory complications
0.000 0.493 0.507
E12.4 With neurological complications
0.000 0.493 0.507
E12.3 With ophthalmic complications
0.000 0.493 0.507
E12.2 With renal complications
0.000 0.493 0.507
E12.1 With ketoacidosis
0.000 0.493 0.507
E12.0 With coma
0.000 0.493 0.507
M06.8 Other specified rheumatoid arthritis
0.000 0.495 0.505
E22.1 Hyperprolactinaemia
0.000 0.497 0.503
E11.6 With other specified complications
0.000 0.497 0.503
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.497 0.502
E04.2 Non-toxic multinodular goitre
0.000 0.507 0.493
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.511 0.489
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.511 0.489
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.511 0.489
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.511 0.489
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.511 0.489
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.511 0.489
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.511 0.489
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.511 0.489
E20.8 Other hypoparathyroidism
0.000 0.516 0.484
E20.1 Pseudohypoparathyroidism
0.000 0.516 0.484
E20.0 Idiopathic hypoparathyroidism
0.000 0.516 0.484
K90.8 Other intestinal malabsorption
0.000 0.516 0.484
E14.5 With peripheral circulatory complications
0.000 0.517 0.482
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.521 0.479
E26 Hyperaldosteronism
0.000 0.522 0.478
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.524 0.476
E29 Testicular dysfunction
0.000 0.530 0.470
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.532 0.468
E45 Retarded development following protein-energy malnutrition
0.000 0.532 0.468
E43 Unspecified severe protein-energy malnutrition
0.000 0.532 0.468
E42 Marasmic kwashiorkor
0.000 0.532 0.468
E41 Nutritional marasmus
0.000 0.532 0.468
E40 Kwashiorkor
0.000 0.532 0.468
E23 Hypofunction and other disorders of pituitary gland
0.000 0.532 0.468
E06.9 Thyroiditis, unspecified
0.000 0.535 0.465
E50-E64 Other nutritional deficiencies
0.000 0.536 0.464
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.539 0.461
E14.4 With neurological complications
0.000 0.541 0.459
H35.6 Retinal haemorrhage
0.000 0.545 0.455
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.545 0.455
E28.3 Primary ovarian failure
0.000 0.546 0.454
H30.9 Chorioretinal inflammation, unspecified
0.000 0.546 0.453
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.550 0.450
K90.3 Pancreatic steatorrhoea
0.000 0.552 0.448
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.552 0.448
K90.1 Tropical sprue
0.000 0.552 0.448
E11.0 With coma
0.000 0.554 0.446
E06.1 Subacute thyroiditis
0.000 0.554 0.445
M06.34 Rheumatoid nodule (Hand)
0.000 0.558 0.442
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.558 0.441
H30.8 Other chorioretinal inflammations
0.000 0.559 0.441
H30.2 Posterior cyclitis
0.000 0.559 0.441
H30.1 Disseminated chorioretinal inflammation
0.000 0.559 0.441
H30.0 Focal chorioretinal inflammation
0.000 0.559 0.441
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.560 0.440
M06.38 Rheumatoid nodule (Other)
0.000 0.560 0.440
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.560 0.440
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.560 0.440
M06.33 Rheumatoid nodule (Forearm)
0.000 0.560 0.440
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.560 0.440
E28.9 Ovarian dysfunction, unspecified
0.000 0.565 0.435
E28.8 Other ovarian dysfunction
0.000 0.565 0.435
E28.1 Androgen excess
0.000 0.565 0.435
E28.0 Oestrogen excess
0.000 0.565 0.435
E46 Unspecified protein-energy malnutrition
0.000 0.566 0.434
H32.8 Other chorioretinal disorders in diseases classified elsewhere
0.000 0.567 0.432
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere
0.000 0.567 0.432
E05.8 Other thyrotoxicosis
0.001 0.570 0.429
E30.9 Disorder of puberty, unspecified
0.000 0.570 0.430
E30.8 Other disorders of puberty
0.000 0.570 0.430
E30.1 Precocious puberty
0.000 0.570 0.430
E30.0 Delayed puberty
0.000 0.570 0.430
E31.9 Polyglandular dysfunction, unspecified
0.000 0.570 0.430
E31.8 Other polyglandular dysfunction
0.000 0.570 0.430
E31.1 Polyglandular hyperfunction
0.000 0.570 0.430
E31.0 Autoimmune polyglandular failure
0.000 0.570 0.430
E32.9 Disease of thymus, unspecified
0.000 0.570 0.430
E32.8 Other diseases of thymus
0.000 0.570 0.430
E32.1 Abscess of thymus
0.000 0.570 0.430
E32.0 Persistent hyperplasia of thymus
0.000 0.570 0.430
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.570 0.430
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.570 0.430
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.570 0.430
K91.0 Vomiting following gastro-intestinal surgery
0.000 0.576 0.424
E28.2 Polycystic ovarian syndrome
0.000 0.577 0.423
E25.9 Adrenogenital disorder, unspecified
0.000 0.577 0.422
E25.8 Other adrenogenital disorders
0.000 0.577 0.422
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.581 0.419
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.581 0.419
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.581 0.419
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.581 0.419
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.581 0.419
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.581 0.419
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.581 0.419
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.581 0.419
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.587 0.412
E27.9 Disorder of adrenal gland, unspecified
0.000 0.589 0.410
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.595 0.405
H35.7 Separation of retinal layers
0.000 0.599 0.401
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.600 0.400
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.600 0.399
M06.18 Adult-onset Still's disease (Other)
0.000 0.600 0.399
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.600 0.399
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.600 0.399
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.600 0.399
M06.14 Adult-onset Still's disease (Hand)
0.000 0.600 0.399
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.600 0.399
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.600 0.399
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.600 0.399
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.600 0.399
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.600 0.399
M06.28 Rheumatoid bursitis (Other)
0.000 0.600 0.399
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.600 0.399
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.600 0.399
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.600 0.399
M06.24 Rheumatoid bursitis (Hand)
0.000 0.600 0.399
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.600 0.399
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.600 0.399
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.600 0.399
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.600 0.399
E14.9 Without complications
0.000 0.602 0.398
H31.3 Choroidal haemorrhage and rupture
0.000 0.605 0.395
H31.8 Other specified disorders of choroid
0.000 0.608 0.392
E23.6 Other disorders of pituitary gland
0.000 0.612 0.388
H31.4 Choroidal detachment
0.000 0.619 0.380
H31.2 Hereditary choroidal dystrophy
0.000 0.619 0.380
K91.2 Postsurgical malabsorption, not elsewhere classified
0.000 0.622 0.378
E13.8 With unspecified complications
0.000 0.624 0.376
E13.7 With multiple complications
0.000 0.624 0.376
E13.6 With other specified complications
0.000 0.624 0.376
E13.5 With peripheral circulatory complications
0.000 0.624 0.376
E13.4 With neurological complications
0.000 0.624 0.376
E13.3 With ophthalmic complications
0.000 0.624 0.376
E13.2 With renal complications
0.000 0.624 0.376
E13.1 With ketoacidosis
0.000 0.624 0.376
E13.0 With coma
0.000 0.624 0.376
E24.2 Drug-induced Cushing's syndrome
0.000 0.624 0.376
H31.9 Disorder of choroid, unspecified
0.000 0.626 0.374
E34 Other endocrine disorders
0.000 0.628 0.372
H31.1 Choroidal degeneration
0.000 0.628 0.372
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.630 0.370
E24.8 Other Cushing's syndrome
0.000 0.636 0.364
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.636 0.364
E24.3 Ectopic ACTH syndrome
0.000 0.636 0.364
E24.1 Nelson's syndrome
0.000 0.636 0.364
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.638 0.362
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.638 0.362
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.638 0.362
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.638 0.362
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.638 0.362
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.638 0.362
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.638 0.362
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.638 0.362
E24.0 Pituitary-dependent Cushing's disease
0.000 0.640 0.360
E51 Thiamine deficiency
0.000 0.648 0.352
K91.9 Postprocedural disorder of digestive system, unspecified
0.000 0.652 0.348
H34.1 Central retinal artery occlusion
0.001 0.656 0.343
E26.8 Other hyperaldosteronism
0.000 0.657 0.343
E26.1 Secondary hyperaldosteronism
0.000 0.657 0.343
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.659 0.341
K91.5 Postcholecystectomy syndrome
0.000 0.659 0.340
E58 Dietary calcium deficiency
0.000 0.662 0.338
E29.8 Other testicular dysfunction
0.000 0.663 0.337
E29.0 Testicular hyperfunction
0.000 0.663 0.337
E44.1 Mild protein-energy malnutrition
0.000 0.664 0.336
E44.0 Moderate protein-energy malnutrition
0.000 0.664 0.336
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.664 0.336
E23.1 Drug-induced hypopituitarism
0.000 0.664 0.336
K91.1 Postgastric surgery syndromes
0.000 0.665 0.335
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.665 0.335
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.667 0.333
E63 Other nutritional deficiencies
0.000 0.667 0.333
E50 Vitamin A deficiency
0.000 0.667 0.333
E60 Dietary zinc deficiency
0.000 0.667 0.333
E59 Dietary selenium deficiency
0.000 0.667 0.333
E54 Ascorbic acid deficiency
0.000 0.667 0.333
E52 Niacin deficiency [pellagra]
0.000 0.667 0.333
E55 Vitamin D deficiency
0.000 0.679 0.321
E56 Other vitamin deficiencies
0.000 0.683 0.316
E29.9 Testicular dysfunction, unspecified
0.000 0.684 0.316
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.312 0.688 0.000
H35.4 Peripheral retinal degeneration
0.000 0.690 0.310
E23.2 Diabetes insipidus
0.000 0.693 0.307
H35.9 Retinal disorder, unspecified
0.000 0.693 0.307
E65-E68 Obesity and other hyperalimentation
0.000 0.696 0.304
E26.9 Hyperaldosteronism, unspecified
0.000 0.703 0.296
K91.3 Postoperative intestinal obstruction
0.000 0.707 0.293
E23.7 Disorder of pituitary gland, unspecified
0.000 0.708 0.292
H31.0 Chorioretinal scars
0.000 0.711 0.289
E26.0 Primary hyperaldosteronism
0.000 0.712 0.287
E51.2 Wernicke's encephalopathy
0.000 0.728 0.272
E03 Other hypothyroidism
0.000 0.729 0.271
E34.5 Androgen resistance syndrome
0.000 0.733 0.267
E34.4 Constitutional tall stature
0.000 0.733 0.267
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.733 0.267
E34.1 Other hypersecretion of intestinal hormones
0.000 0.733 0.267
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.734 0.265
K93.1 Megacolon in Chagas' disease
0.000 0.734 0.265
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.734 0.265
R31 Unspecified haematuria
0.262 0.738 0.000
E34.0 Carcinoid syndrome
0.000 0.738 0.262
E53 Deficiency of other B group vitamins
0.000 0.741 0.258
E24.9 Cushing's syndrome, unspecified
0.000 0.743 0.257
E04.1 Non-toxic single thyroid nodule
0.000 0.744 0.256
E51.9 Thiamine deficiency, unspecified
0.000 0.747 0.252
E51.8 Other manifestations of thiamine deficiency
0.000 0.747 0.252
E51.1 Beriberi
0.000 0.747 0.252
E34.3 Short stature, not elsewhere classified
0.000 0.755 0.245
E29.1 Testicular hypofunction
0.000 0.756 0.243
E50.9 Vitamin A deficiency, unspecified
0.000 0.761 0.238
E50.8 Other manifestations of vitamin A deficiency
0.000 0.761 0.238
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.761 0.238
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.761 0.238
E50.5 Vitamin A deficiency with night blindness
0.000 0.761 0.238
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.761 0.238
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.761 0.238
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.761 0.238
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.761 0.238
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.761 0.238
E63.9 Nutritional deficiency, unspecified
0.000 0.761 0.238
E63.8 Other specified nutritional deficiencies
0.000 0.761 0.238
E63.1 Imbalance of constituents of food intake
0.000 0.761 0.238
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.761 0.238
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.761 0.238
E64.8 Sequelae of other nutritional deficiencies
0.000 0.761 0.238
E64.3 Sequelae of rickets
0.000 0.761 0.238
E64.2 Sequelae of vitamin C deficiency
0.000 0.761 0.238
E64.1 Sequelae of vitamin A deficiency
0.000 0.761 0.238
E64.0 Sequelae of protein-energy malnutrition
0.000 0.761 0.238
E61 Deficiency of other nutrient elements
0.000 0.764 0.236
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.235 0.765 0.000
E55.0 Rickets, active
0.000 0.769 0.230
E56.9 Vitamin deficiency, unspecified
0.000 0.773 0.227
E56.8 Deficiency of other vitamins
0.000 0.773 0.227
E56.0 Deficiency of vitamin E
0.000 0.773 0.227
E34.8 Other specified endocrine disorders
0.000 0.777 0.223
E55.9 Vitamin D deficiency, unspecified
0.000 0.781 0.219
E67 Other hyperalimentation
0.000 0.782 0.218
E68 Sequelae of hyperalimentation
0.000 0.782 0.218
E56.1 Deficiency of vitamin K
0.000 0.789 0.211
C82.3 Follicular lymphoma grade IIIa
0.202 0.798 0.000
E23.0 Hypopituitarism
0.000 0.799 0.200
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.196 0.804 0.000
E03.5 Myxoedema coma
0.000 0.805 0.195
E03.4 Atrophy of thyroid (acquired)
0.000 0.805 0.195
E03.3 Postinfectious hypothyroidism
0.000 0.805 0.195
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.805 0.195
E13.9 Without complications
0.001 0.806 0.194
C82.1 Mixed small cleaved and large cell, follicular
0.190 0.810 0.000
E34.9 Endocrine disorder, unspecified
0.001 0.813 0.186
E53.1 Pyridoxine deficiency
0.000 0.814 0.185
E53.0 Riboflavin deficiency
0.000 0.814 0.185
K90.9 Intestinal malabsorption, unspecified
0.001 0.814 0.185
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.814 0.185
E03.8 Other specified hypothyroidism
0.000 0.817 0.183
C82.0 Small cleaved cell, follicular
0.182 0.818 0.000
H33.0 Retinal detachment with retinal break
0.000 0.826 0.174
E53.9 Vitamin B deficiency, unspecified
0.000 0.827 0.172
E61.2 Magnesium deficiency
0.000 0.828 0.172
E61.9 Deficiency of nutrient element, unspecified
0.000 0.830 0.169
E61.8 Deficiency of other specified nutrient elements
0.000 0.830 0.169
E61.7 Deficiency of multiple nutrient elements
0.000 0.830 0.169
E61.6 Vanadium deficiency
0.000 0.830 0.169
E61.5 Molybdenum deficiency
0.000 0.830 0.169
E61.4 Chromium deficiency
0.000 0.830 0.169
E61.3 Manganese deficiency
0.000 0.830 0.169
E61.0 Copper deficiency
0.000 0.830 0.169
C82.6 Cutaneous follicle centre lymphoma
0.168 0.831 0.000
C82.5 Diffuse follicle centre lymphoma
0.168 0.831 0.000
C82.4 Follicular lymphoma grade IIIb
0.167 0.833 0.000
E03.1 Congenital hypothyroidism without goitre
0.000 0.836 0.164
H35.3 Degeneration of macula and posterior pole
0.000 0.838 0.162
H33.5 Other retinal detachments
0.002 0.842 0.156
E67.8 Other specified hyperalimentation
0.000 0.843 0.156
E67.3 Hypervitaminosis D
0.000 0.843 0.156
E67.2 Megavitamin-B6 syndrome
0.000 0.843 0.156
E67.1 Hypercarotenaemia
0.000 0.843 0.156
E67.0 Hypervitaminosis A
0.000 0.843 0.156
M05-M14 Inflammatory polyarthropathies
0.000 0.853 0.147
E65 Localised adiposity
0.000 0.854 0.146
C82.2 Large cell, follicular
0.136 0.864 0.000
E53.8 Deficiency of other specified B group vitamins
0.000 0.866 0.133
M10 Gout
0.000 0.879 0.121
M14 Arthropathies in other diseases classified elsewhere
0.000 0.891 0.109
M12 Other specific arthropathies
0.000 0.893 0.107
E11.4 With neurological complications
0.001 0.893 0.107
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.894 0.105
M07 Psoriatic and enteropathic arthropathies
0.000 0.897 0.103
M08 Juvenile arthritis
0.000 0.899 0.101
M10.0 Idiopathic gout
0.000 0.902 0.098
E07.9 Disorder of thyroid, unspecified
0.002 0.904 0.095
M10.9 Gout, unspecified
0.000 0.906 0.094
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.002 0.908 0.091
M10.4 Other secondary gout
0.000 0.913 0.087
M10.3 Gout due to impairment of renal function
0.000 0.913 0.087
M10.2 Drug-induced gout
0.000 0.913 0.087
M10.1 Lead-induced gout
0.000 0.913 0.087
M13 Other arthritis
0.000 0.913 0.087
M10.07 Idiopathic gout (Ankle and foot)
0.000 0.915 0.085
M10.93 Gout, unspecified (Forearm)
0.000 0.918 0.082
M11 Other crystal arthropathies
0.000 0.918 0.082
M14.6 Neuropathic arthropathy
0.000 0.919 0.081
M10.90 Gout, unspecified (Multiple sites)
0.000 0.919 0.081
M12.3 Palindromic rheumatism
0.000 0.919 0.081
M14.8 Arthropathies in other specified diseases classified elsewhere
0.000 0.922 0.078
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.922 0.078
M14.4 Arthropathy in amyloidosis
0.000 0.922 0.078
M14.3 Lipoid dermatoarthritis
0.000 0.922 0.078
M14.2 Diabetic arthropathy
0.000 0.922 0.078
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.922 0.078
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.922 0.078
M12.8 Other specific arthropathies, not elsewhere classified
0.000 0.923 0.077
M12.5 Traumatic arthropathy
0.000 0.923 0.077
M12.4 Intermittent hydrarthrosis
0.000 0.923 0.077
M12.1 Kaschin-Beck disease
0.000 0.923 0.077
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.000 0.923 0.077
M10.94 Gout, unspecified (Hand)
0.000 0.924 0.076
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.000 0.924 0.076
M09.2 Juvenile arthritis in ulcerative colitis
0.000 0.924 0.076
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.000 0.924 0.076
M09.0 Juvenile arthritis in psoriasis
0.000 0.924 0.076
M12.2 Villonodular synovitis (pigmented)
0.000 0.924 0.075
M07.6 Other enteropathic arthropathies
0.000 0.926 0.074
M07.5 Arthropathy in ulcerative colitis
0.000 0.926 0.074
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.926 0.074
M07.2 Psoriatic spondylitis
0.000 0.926 0.074
M07.1 Arthritis mutilans
0.000 0.926 0.074
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.926 0.074
M08.9 Juvenile arthritis, unspecified
0.000 0.928 0.072
M08.8 Other juvenile arthritis
0.000 0.928 0.072
M08.4 Pauciarticular juvenile arthritis
0.000 0.928 0.072
M08.3 Juvenile polyarthritis (seronegative)
0.000 0.928 0.072
M08.2 Juvenile arthritis with systemic onset
0.000 0.928 0.072
M08.1 Juvenile ankylosing spondylitis
0.000 0.928 0.072
M07.3 Other psoriatic arthropathies
0.000 0.928 0.072
M13.0 Polyarthritis, unspecified
0.000 0.928 0.072
M10.08 Idiopathic gout (Other)
0.000 0.929 0.070
M10.06 Idiopathic gout (Lower leg)
0.000 0.929 0.070
M10.05 Idiopathic gout (Pelvic region and thigh)
0.000 0.929 0.070
M10.04 Idiopathic gout (Hand)
0.000 0.929 0.070
M10.03 Idiopathic gout (Forearm)
0.000 0.929 0.070
M10.02 Idiopathic gout (Upper arm)
0.000 0.929 0.070
M10.01 Idiopathic gout (Shoulder region)
0.000 0.929 0.070
M10.00 Idiopathic gout (Multiple sites)
0.000 0.929 0.070
M13.1 Monoarthritis, not elsewhere classified
0.000 0.931 0.069
M08.0 Juvenile rheumatoid arthritis
0.000 0.932 0.067
M10.98 Gout, unspecified (Other)
0.000 0.932 0.067
M10.95 Gout, unspecified (Pelvic region and thigh)
0.000 0.932 0.067
M10.91 Gout, unspecified (Shoulder region)
0.000 0.932 0.067
M10.97 Gout, unspecified (Ankle and foot)
0.000 0.933 0.067
E21.4 Other specified disorders of parathyroid gland
0.002 0.933 0.065
E61.1 Iron deficiency
0.001 0.934 0.065

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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