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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant cluster associations

Hospitalization Episode Statistics (HES)

Cluster X0071
log Bayes Factor = 131.269
contains 6 variants:
rs7516789
lBF = 13.684
Chr 1 : 67,945,956
rs115158632
lBF = 14.320
Chr 4 : 118,088,133
rs75583295
lBF = 19.574
Chr 8 : 63,596,650
rs72649226
lBF = 15.405
Chr 8 : 64,550,665
rs75004325
lBF = 14.319
Chr 9 : 73,586,372
rs117599750
lBF = 11.787
Chr15 : 40,091,332
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E11 Non-insulin-dependent diabetes mellitus
1.000 0.000 0.000
M47 Spondylosis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
G90-G99 Other disorders of the nervous system
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
M80-M85 Disorders of bone density and structure
1.000 0.000 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
1.000 0.000 0.000
J22 Unspecified acute lower respiratory infection
1.000 0.000 0.000
M47.8 Other spondylosis
1.000 0.000 0.000
E20-E35 Disorders of other endocrine glands
1.000 0.000 0.000
M45-M49 Spondylopathies
1.000 0.000 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
J20-J22 Other acute lower respiratory infections
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
1.000 0.000 0.000
M23 Internal derangement of knee
1.000 0.000 0.000
M25 Other joint disorders, not elsewhere classified
1.000 0.000 0.000
R79 Other abnormal findings of blood chemistry
1.000 0.000 0.000
Z50 Care involving use of rehabilitation procedures
1.000 0.000 0.000
Z43 Attention to artificial openings
1.000 0.000 0.000
R79.8 Other specified abnormal findings of blood chemistry
1.000 0.000 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.999 0.001 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.999 0.001 0.000
W00-W19 Falls
0.999 0.001 0.000
I49 Other cardiac arrhythmias
0.999 0.001 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.999 0.001 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.999 0.001 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.999 0.001 0.000
M21 Other acquired deformities of limbs
0.999 0.001 0.000
M06 Other rheumatoid arthritis
0.999 0.001 0.000
M81 Osteoporosis without pathological fracture
0.999 0.001 0.000
H30-H36 Disorders of choroid and retina
0.999 0.001 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.998 0.002 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.998 0.002 0.000
M47.9 Spondylosis, unspecified
0.998 0.002 0.000
G95 Other diseases of spinal cord
0.998 0.002 0.000
M81.9 Osteoporosis, unspecified
0.998 0.002 0.000
S80-S89 Injuries to the knee and lower leg
0.998 0.002 0.000
E11.9 Without complications
0.998 0.002 0.000
M25.7 Osteophyte
0.998 0.002 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.997 0.003 0.000
H36 Retinal disorders in diseases classified elsewhere
0.997 0.003 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.997 0.003 0.000
H36.0 Diabetic retinopathy
0.997 0.003 0.000
J95-J99 Other diseases of the respiratory system
0.997 0.003 0.000
M47.82 Other spondylosis (Cervical region)
0.996 0.004 0.000
Chapter XXII Codes for special purposes
0.996 0.004 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.996 0.004 0.000
M47.86 Other spondylosis (Lumbar region)
0.996 0.004 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.996 0.004 0.000
E10.3 With ophthalmic complications
0.996 0.004 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.996 0.004 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.996 0.004 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.996 0.004 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.995 0.005 0.000
Z43.2 Attention to ileostomy
0.995 0.005 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.995 0.005 0.000
E70-E90 Metabolic disorders
0.994 0.006 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.994 0.006 0.000
M84 Disorders of continuity of bone
0.994 0.006 0.000
G93 Other disorders of brain
0.993 0.007 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.993 0.007 0.000
M70-M79 Other soft tissue disorders
0.993 0.007 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.993 0.007 0.000
M06.9 Rheumatoid arthritis, unspecified
0.992 0.008 0.000
E10.4 With neurological complications
0.992 0.008 0.000
C15-C26 Malignant neoplasms of digestive organs
0.992 0.008 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.991 0.009 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.991 0.009 0.000
S60-S69 Injuries to the wrist and hand
0.990 0.010 0.000
F30-F39 Mood [affective] disorders
0.990 0.010 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.989 0.011 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.988 0.012 0.000
G81 Hemiplegia
0.988 0.012 0.000
Z02 Examination and encounter for administrative purposes
0.988 0.012 0.000
M24 Other specific joint derangements
0.988 0.012 0.000
M25.78 Osteophyte (Other)
0.987 0.013 0.000
I34 Nonrheumatic mitral valve disorders
0.987 0.013 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.986 0.014 0.000
I35 Nonrheumatic aortic valve disorders
0.986 0.014 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.985 0.015 0.000
M21.3 Wrist or foot drop (acquired)
0.984 0.016 0.000
J95.8 Other postprocedural respiratory disorders
0.984 0.016 0.000
Z02.8 Other examinations for administrative purposes
0.984 0.016 0.000
G40-G47 Episodic and paroxysmal disorders
0.983 0.017 0.000
G81.9 Hemiplegia, unspecified
0.983 0.017 0.000
I35.0 Aortic (valve) stenosis
0.983 0.017 0.000
S00-S09 Injuries to the head
0.982 0.018 0.000
Z50.5 Speech therapy
0.982 0.018 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.982 0.018 0.000
Z45 Adjustment and management of implanted device
0.981 0.019 0.000
R23 Other skin changes
0.981 0.019 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.981 0.019 0.000
M50-M54 Other dorsopathies
0.981 0.019 0.000
I51 Complications and ill-defined descriptions of heart disease
0.980 0.020 0.000
E11.3 With ophthalmic complications
0.980 0.020 0.000
I34.1 Mitral (valve) prolapse
0.980 0.020 0.000
M25.76 Osteophyte (Lower leg)
0.980 0.020 0.000
S81 Open wound of lower leg
0.979 0.021 0.000
E27 Other disorders of adrenal gland
0.979 0.021 0.000
H52 Disorders of refraction and accommodation
0.979 0.021 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.979 0.021 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.979 0.021 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.978 0.022 0.000
M25.8 Other specified joint disorders
0.978 0.022 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.977 0.023 0.000
H52.1 Myopia
0.977 0.023 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.976 0.024 0.000
E83 Disorders of mineral metabolism
0.976 0.024 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.975 0.025 0.000
I49.3 Ventricular premature depolarisation
0.974 0.026 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.974 0.026 0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)
0.974 0.026 0.000
M54 Dorsalgia
0.973 0.027 0.000
F10.0 Acute intoxication
0.973 0.027 0.000
Y83.3 Surgical operation with formation of external stoma
0.972 0.028 0.000
M86-M90 Other osteopathies
0.972 0.028 0.000
Y83.4 Other reconstructive surgery
0.971 0.029 0.000
M05 Seropositive rheumatoid arthritis
0.970 0.030 0.000
R22.1 Localised swelling, mass and lump, neck
0.970 0.030 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.970 0.030 0.000
G40 Epilepsy
0.968 0.032 0.000
R23.3 Spontaneous ecchymoses
0.965 0.035 0.000
G95.2 Cord compression, unspecified
0.965 0.035 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.965 0.035 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.964 0.036 0.000
V10-V19 Pedal cyclist injured in transport accident
0.964 0.036 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.964 0.036 0.000
E11.5 With peripheral circulatory complications
0.964 0.036 0.000
M54.2 Cervicalgia
0.963 0.037 0.000
D80-D89 Certain disorders involving the immune mechanism
0.963 0.037 0.000
J60-J70 Lung diseases due to external agents
0.962 0.038 0.000
L20-L30 Dermatitis and eczema
0.962 0.038 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.962 0.038 0.000
U80 Agent resistant to penicillin and related antibiotics
0.961 0.039 0.000
Z57 Occupational exposure to risk-factors
0.960 0.040 0.000
F10.1 Harmful use
0.960 0.040 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.960 0.040 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.959 0.041 0.000
H49 Paralytic strabismus
0.959 0.041 0.000
E29 Testicular dysfunction
0.959 0.041 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.958 0.042 0.000
E21.0 Primary hyperparathyroidism
0.957 0.043 0.000
E73 Lactose intolerance
0.954 0.046 0.000
S67 Crushing injury of wrist and hand
0.953 0.047 0.000
L30 Other dermatitis
0.953 0.047 0.000
Q80-Q89 Other congenital malformations
0.953 0.047 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.953 0.047 0.000
M54.22 Cervicalgia (Cervical region)
0.952 0.048 0.000
M85 Other disorders of bone density and structure
0.951 0.049 0.000
G59.0 Diabetic mononeuropathy
0.951 0.049 0.000
I49.0 Ventricular fibrillation and flutter
0.951 0.049 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.950 0.050 0.000
W19 Unspecified fall
0.950 0.050 0.000
E11.4 With neurological complications
0.949 0.051 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.949 0.051 0.000
J69 Pneumonitis due to solids and liquids
0.949 0.051 0.000
I51.9 Heart disease, unspecified
0.949 0.051 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.948 0.052 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.948 0.052 0.000
Chapter VIII Diseases of the ear and mastoid process
0.947 0.053 0.000
L30.9 Dermatitis, unspecified
0.947 0.053 0.000
R22.0 Localised swelling, mass and lump, head
0.946 0.054 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.946 0.054 0.000
E83.1 Disorders of iron metabolism
0.945 0.055 0.000
M47.2 Other spondylosis with radiculopathy
0.945 0.055 0.000
G63.2 Diabetic polyneuropathy
0.945 0.055 0.000
F33 Recurrent depressive disorder
0.944 0.056 0.000
D72 Other disorders of white blood cells
0.944 0.056 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.943 0.057 0.000
G95.8 Other specified diseases of spinal cord
0.943 0.057 0.000
I05-I09 Chronic rheumatic heart diseases
0.942 0.058 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.941 0.059 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.941 0.059 0.000
S10-S19 Injuries to the neck
0.940 0.060 0.000
J69.0 Pneumonitis due to food and vomit
0.940 0.060 0.000
S00 Superficial injury of head
0.939 0.061 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.939 0.061 0.000
M47.89 Other spondylosis (Site unspecified)
0.939 0.061 0.000
F10.3 Withdrawal state
0.938 0.062 0.000
D86 Sarcoidosis
0.936 0.064 0.000
U51 Admission status on psychiatric patients
0.936 0.064 0.000
M23.3 Other meniscus derangements
0.935 0.065 0.000
Chapter I Certain infectious and parasitic diseases
0.935 0.065 0.000
R21 Rash and other nonspecific skin eruption
0.934 0.066 0.000
M89 Other disorders of bone
0.934 0.066 0.000
D73 Diseases of spleen
0.934 0.066 0.000
W18 Other fall on same level
0.934 0.066 0.000
Y52 Agents primarily affecting the cardiovascular system
0.933 0.067 0.000
H25-H28 Disorders of lens
0.932 0.068 0.000
M82 Osteoporosis in diseases classified elsewhere
0.931 0.069 0.000
R22.3 Localised swelling, mass and lump, upper limb
0.931 0.069 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.931 0.069 0.000
M25.87 Other specified joint disorders (Ankle and foot)
0.930 0.070 0.000
E29.1 Testicular hypofunction
0.930 0.070 0.000
D60-D64 Aplastic and other anaemias
0.929 0.071 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.929 0.071 0.000
G95.1 Vascular myelopathies
0.929 0.071 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.929 0.071 0.000
M22 Disorders of patella
0.929 0.071 0.000
M21.0 Valgus deformity, not elsewhere classified
0.928 0.072 0.000
D68 Other coagulation defects
0.928 0.072 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.927 0.073 0.000
S67.0 Crushing injury of thumb and other finger(s)
0.927 0.073 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.926 0.074 0.000
E73.9 Lactose intolerance, unspecified
0.925 0.075 0.000
R02 Gangrene, not elsewhere classified
0.925 0.075 0.000
D46 Myelodysplastic syndromes
0.925 0.075 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.924 0.076 0.000
E10.9 Without complications
0.924 0.076 0.000
S00.0 Superficial injury of scalp
0.924 0.076 0.000
R22.2 Localised swelling, mass and lump, trunk
0.923 0.077 0.000
G58 Other mononeuropathies
0.921 0.079 0.000
H49.2 Sixth [abducent] nerve palsy
0.920 0.080 0.000
Z54 Convalescence
0.920 0.080 0.000
R79.9 Abnormal finding of blood chemistry, unspecified
0.920 0.080 0.000
S80 Superficial injury of lower leg
0.919 0.081 0.000
T91 Sequelae of injuries of neck and trunk
0.919 0.081 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.919 0.081 0.000
R79.0 Abnormal level of blood mineral
0.918 0.082 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.917 0.083 0.000
E10.5 With peripheral circulatory complications
0.917 0.083 0.000
Z57.2 Occupational exposure to dust
0.917 0.083 0.000
S01 Open wound of head
0.917 0.083 0.000
I49.9 Cardiac arrhythmia, unspecified
0.916 0.084 0.000
V18.0 Driver injured in nontraffic accident
0.916 0.084 0.000
H90-H95 Other disorders of ear
0.916 0.084 0.000
R71 Abnormality of red blood cells
0.916 0.084 0.000
Q50-Q56 Congenital malformations of genital organs
0.915 0.085 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.915 0.085 0.000
F31 Bipolar affective disorder
0.914 0.086 0.000
M65-M68 Disorders of synovium and tendon
0.914 0.086 0.000
M06.3 Rheumatoid nodule
0.914 0.086 0.000
I30 Acute pericarditis
0.913 0.087 0.000
M23.8 Other internal derangements of knee
0.913 0.087 0.000
G54 Nerve root and plexus disorders
0.912 0.088 0.000
Z01.8 Other specified special examinations
0.912 0.088 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.912 0.088 0.000
G70-G73 Diseases of myoneural junction and muscle
0.912 0.088 0.000
T93 Sequelae of injuries of lower limb
0.912 0.088 0.000
M77 Other enthesopathies
0.912 0.088 0.000
Z43.5 Attention to cyctostomy
0.912 0.088 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.911 0.089 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.911 0.089 0.000
Q60-Q64 Congenital malformations of the urinary system
0.910 0.090 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.910 0.090 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.910 0.090 0.000
L60-L75 Disorders of skin appendages
0.909 0.091 0.000
E11.2 With renal complications
0.909 0.091 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.909 0.091 0.000
C25 Malignant neoplasm of pancreas
0.909 0.091 0.000
Z50.1 Other physical therapy
0.907 0.093 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.906 0.094 0.000
L40-L45 Papulosquamous disorders
0.905 0.095 0.000
E27.8 Other specified disorders of adrenal gland
0.904 0.096 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.904 0.096 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.903 0.097 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.903 0.097 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.902 0.098 0.000
D61 Other aplastic anaemias
0.902 0.098 0.000
C17 Malignant neoplasm of small intestine
0.900 0.100 0.000
H55-H59 Other disorders of eye and adnexa
0.900 0.100 0.000
Y40 Systemic antibiotics
0.899 0.101 0.000
T90 Sequelae of injuries of head
0.898 0.102 0.000
G60 Hereditary and idiopathic neuropathy
0.898 0.102 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.897 0.103 0.000
M21.1 Varus deformity, not elsewhere classified
0.897 0.103 0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)
0.896 0.104 0.000
M71 Other bursopathies
0.896 0.104 0.000
M76 Enthesopathies of lower limb, excluding foot
0.896 0.104 0.000
S62 Fracture at wrist and hand level
0.896 0.104 0.000
M89.9 Disorder of bone, unspecified
0.896 0.104 0.000
S81.9 Open wound of lower leg, part unspecified
0.895 0.105 0.000
E10.2 With renal complications
0.895 0.105 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.895 0.105 0.000
S01.5 Open wound of lip and oral cavity
0.894 0.106 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.894 0.106 0.000
S90-S99 Injuries to the ankle and foot
0.893 0.107 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.893 0.107 0.000
S89 Other and unspecified injuries of lower leg
0.893 0.107 0.000
S81.8 Open wound of other parts of lower leg
0.892 0.108 0.000
M06.0 Seronegative rheumatoid arthritis
0.892 0.108 0.000
H34 Retinal vascular occlusions
0.891 0.109 0.000
E83.3 Disorders of phosphorus metabolism
0.890 0.110 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.890 0.110 0.000
V80-V89 Other land transport accidents
0.890 0.110 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.889 0.111 0.000
Z22 Carrier of infectious disease
0.889 0.111 0.000
H27 Other disorders of lens
0.889 0.111 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.889 0.111 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.888 0.112 0.000
G35 Multiple sclerosis
0.887 0.113 0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
0.887 0.113 0.000
J09-J18 Influenza and pneumonia
0.886 0.114 0.000
R07 Pain in throat and chest
0.886 0.114 0.000
D73.5 Infarction of spleen
0.886 0.114 0.000
R07.2 Precordial pain
0.886 0.114 0.000
M81.4 Drug-induced osteoporosis
0.885 0.115 0.000
C20 Malignant neoplasm of rectum
0.885 0.115 0.000
M22.4 Chondromalacia patellae
0.884 0.116 0.000
C16 Malignant neoplasm of stomach
0.884 0.116 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.884 0.116 0.000
M25.72 Osteophyte (Upper arm)
0.883 0.117 0.000
U80.8 Agent resistant to other penicillin-related antibiotic
0.883 0.117 0.000
D61.9 Aplastic anaemia, unspecified
0.882 0.118 0.000
D47.1 Chronic myeloproliferative disease
0.882 0.118 0.000
M79.1 Myalgia
0.882 0.118 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.881 0.119 0.000
M82.1 Osteoporosis in endocrine disorders
0.881 0.119 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.881 0.119 0.000
D72.8 Other specified disorders of white blood cells
0.881 0.119 0.000
S82 Fracture of lower leg, including ankle
0.881 0.119 0.000
I05 Rheumatic mitral valve diseases
0.881 0.119 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.880 0.120 0.000
S01.9 Open wound of head, part unspecified
0.879 0.121 0.000
T98 Sequelae of other and unspecified effects of external causes
0.879 0.121 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.879 0.121 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.878 0.122 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.878 0.122 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.878 0.122 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.878 0.122 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.876 0.124 0.000
Y44 Agents primarily affecting blood constituents
0.876 0.124 0.000
G58.8 Other specified mononeuropathies
0.875 0.125 0.000
U80.1 Methicillin resistant agent
0.875 0.125 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.875 0.125 0.000
M85.8 Other specified disorders of bone density and structure
0.875 0.125 0.000
M84.0 Malunion of fracture
0.875 0.125 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.875 0.125 0.000
F60-F69 Disorders of adult personality and behaviour
0.873 0.127 0.000
W19.4 Street and highway
0.873 0.127 0.000
T94.1 Sequelae of injuries, not specified by body region
0.873 0.127 0.000
Z22.3 Carrier of other specified bacterial diseases
0.872 0.128 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.872 0.128 0.000
E40-E46 Malnutrition
0.872 0.128 0.000
G93.2 Benign intracranial hypertension
0.872 0.128 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.871 0.129 0.000
L40 Psoriasis
0.870 0.130 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.869 0.131 0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs
0.869 0.131 0.000
H91 Other hearing loss
0.869 0.131 0.000
F80-F89 Disorders of psychological development
0.869 0.131 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.868 0.132 0.000
M13 Other arthritis
0.867 0.133 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.867 0.133 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.865 0.135 0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)
0.864 0.136 0.000
S20-S29 Injuries to the thorax
0.863 0.137 0.000
Z54.0 Convalescence following surgery
0.863 0.137 0.000
M48 Other spondylopathies
0.863 0.137 0.000
G40.5 Special epileptic syndromes
0.862 0.138 0.000
L60 Nail disorders
0.861 0.139 0.000
C15 Malignant neoplasm of oesophagus
0.861 0.139 0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems
0.861 0.139 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.860 0.140 0.000
E11.6 With other specified complications
0.860 0.140 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.860 0.140 0.000
S62.2 Fracture of first metacarpal bone
0.859 0.141 0.000
S82.2 Fracture of shaft of tibia
0.859 0.141 0.000
I72 Other aneurysm
0.859 0.141 0.000
S12 Fracture of neck
0.859 0.141 0.000
U51.0 Not Previously admitted to a psyciatric hospital
0.858 0.142 0.000
G93.9 Disorder of brain, unspecified
0.858 0.142 0.000
T86 Failure and rejection of transplanted organs and tissues
0.858 0.142 0.000
M14 Arthropathies in other diseases classified elsewhere
0.858 0.142 0.000
M87 Osteonecrosis
0.857 0.143 0.000
D75 Other diseases of blood and blood-forming organs
0.857 0.143 0.000
I49.1 Atrial premature depolarisation
0.856 0.144 0.000
G93.4 Encephalopathy, unspecified
0.856 0.144 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.855 0.145 0.000
C21 Malignant neoplasm of anus and anal canal
0.855 0.145 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.855 0.145 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.855 0.145 0.000
I49.4 Other and unspecified premature depolarisation
0.855 0.145 0.000
E22 Hyperfunction of pituitary gland
0.855 0.145 0.000
W18.5 Trade and service area
0.855 0.145 0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)
0.854 0.146 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.853 0.147 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.853 0.147 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.853 0.147 0.000
Z01.9 Special examination, unspecified
0.853 0.147 0.000
M30 Polyarteritis nodosa and related conditions
0.852 0.148 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.852 0.148 0.000
D48.1 Connective and other soft tissue
0.852 0.148 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.851 0.149 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.851 0.149 0.000
F99-F99 Unspecified mental disorder
0.851 0.149 0.000
D68.9 Coagulation defect, unspecified
0.851 0.149 0.000
R09.3 Abnormal sputum
0.851 0.149 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.850 0.150 0.000
R44.0 Auditory hallucinations
0.850 0.150 0.000
E27.9 Disorder of adrenal gland, unspecified
0.850 0.150 0.000
G51 Facial nerve disorders
0.849 0.151 0.000
D86.9 Sarcoidosis, unspecified
0.848 0.152 0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)
0.848 0.152 0.000
T92 Sequelae of injuries of upper limb
0.848 0.152 0.000
I51.0 Cardiac septal defect, acquired
0.848 0.152 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.848 0.152 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.848 0.152 0.000
J95.0 Tracheostomy malfunction
0.847 0.153 0.000
M24.0 Loose body in joint
0.847 0.153 0.000
E11.1 With ketoacidosis
0.846 0.154 0.000
M54.9 Dorsalgia, unspecified
0.846 0.154 0.000
M46 Other inflammatory spondylopathies
0.845 0.154 0.000
W02.9 Unspecified place
0.845 0.155 0.000
M65 Synovitis and tenosynovitis
0.845 0.155 0.000
W19.2 School, other institution and public administrative area
0.845 0.155 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.844 0.156 0.000
S81.0 Open wound of knee
0.843 0.156 0.000
F10.2 Dependence syndrome
0.843 0.157 0.000
Y40.9 Systemic antibiotic, unspecified
0.843 0.157 0.000
M79.19 Myalgia (Site unspecified)
0.842 0.158 0.000
R44.3 Hallucinations, unspecified
0.842 0.158 0.000
E34 Other endocrine disorders
0.842 0.158 0.000
L60.0 Ingrowing nail
0.841 0.159 0.000
Q89 Other congenital malformations, not elsewhere classified
0.841 0.159 0.000
G93.0 Cerebral cysts
0.841 0.159 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.841 0.159 0.000
W06 Fall involving bed
0.840 0.160 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.840 0.160 0.000
M21.2 Flexion deformity
0.840 0.160 0.000
D48.0 Bone and articular cartilage
0.839 0.161 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.839 0.161 0.000
F30 Manic episode
0.839 0.161 0.000
I70 Atherosclerosis
0.839 0.161 0.000
M13.0 Polyarthritis, unspecified
0.838 0.161 0.000
E85 Amyloidosis
0.838 0.162 0.000
L40.5 Arthropathic psoriasis
0.838 0.162 0.000
I36 Nonrheumatic tricuspid valve disorders
0.838 0.162 0.000
I37 Pulmonary valve disorders
0.838 0.162 0.000
Z76 Persons encountering health services in other circumstances
0.837 0.163 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.837 0.163 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.837 0.163 0.000
R45 Symptoms and signs involving emotional state
0.837 0.163 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.836 0.164 0.000
V40-V49 Car occupant injured in transport accident
0.836 0.164 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.836 0.164 0.000
H91.9 Hearing loss, unspecified
0.835 0.165 0.000
S01.4 Open wound of cheek and temporomandibular area
0.835 0.165 0.000
T91.8 Sequelae of other specified injuries of neck and trunk
0.835 0.165 0.000
S50-S59 Injuries to the elbow and forearm
0.835 0.165 0.000
S70-S79 Injuries to the hip and thigh
0.835 0.165 0.000
C83.3 Large cell (diffuse)
0.835 0.165 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.834 0.166 0.000
Q76 Congenital malformations of spine and bony thorax
0.834 0.166 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.834 0.166 0.000
S62.20 Fracture of first metacarpal bone (closed)
0.833 0.167 0.000
E83.4 Disorders of magnesium metabolism
0.833 0.167 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.833 0.167 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.833 0.167 0.000
G80 Infantile cerebral palsy
0.832 0.168 0.000
Y48 Anaesthetics and therapeutic gases
0.832 0.168 0.000
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances
0.831 0.169 0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.831 0.169 0.000
I30.9 Acute pericarditis, unspecified
0.831 0.169 0.000
Q00-Q07 Congenital malformations of the nervous system
0.830 0.170 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.830 0.170 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.829 0.171 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.829 0.171 0.000
M85.0 Fibrous dysplasia (monostotic)
0.828 0.172 0.000
Z11.4 Special screening examination for human immunodeficiency virus [HIV]
0.828 0.172 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.828 0.172 0.000
M25.9 Joint disorder, unspecified
0.828 0.172 0.000
G90 Disorders of autonomic nervous system
0.827 0.172 0.000
J00-J06 Acute upper respiratory infections
0.828 0.172 0.000
G93.3 Postviral fatigue syndrome
0.827 0.173 0.000
Z01.7 Laboratory examination
0.827 0.173 0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)
0.827 0.173 0.000
M76.6 Achilles tendinitis
0.826 0.174 0.000
Z57.3 Occupational exposure to other air contaminants
0.826 0.174 0.000
C16.9 Stomach, unspecified
0.826 0.174 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.826 0.174 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.825 0.175 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.825 0.175 0.000
Z52 Donors of organs and tissues
0.824 0.176 0.000
W10 Fall on and from stairs and steps
0.824 0.176 0.000
Z73 Problems related to life-management difficulty
0.823 0.177 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.823 0.177 0.000
C88 Malignant immunoproliferative diseases
0.823 0.177 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.823 0.177 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.822 0.177 0.000
G62 Other polyneuropathies
0.822 0.178 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.822 0.178 0.000
I50 Heart failure
0.821 0.179 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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