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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117599750
log Bayes Factor = 11.7875
Chromosome 15   position 40,091,332  (GRCh37) Explore rs117599750 on Ensembl!
Variant rs117599750 is part of Cluster X0071

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.999 0.001 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
E10 Insulin-dependent diabetes mellitus
0.996 0.004 0.000
H30-H36 Disorders of choroid and retina
0.994 0.006 0.000
R94 Abnormal results of function studies
0.992 0.008 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.987 0.013 0.000
R94.5 Abnormal results of liver function studies
0.986 0.014 0.000
Chapter VI Diseases of the nervous system
0.985 0.015 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.983 0.017 0.000
M80-M85 Disorders of bone density and structure
0.979 0.021 0.000
E11 Non-insulin-dependent diabetes mellitus
0.971 0.029 0.000
H36 Retinal disorders in diseases classified elsewhere
0.966 0.034 0.000
Chapter VIII Diseases of the ear and mastoid process
0.963 0.037 0.000
M45-M49 Spondylopathies
0.958 0.042 0.000
Chapter XXI Factors influencing health status and contact with health services
0.957 0.043 0.000
M81 Osteoporosis without pathological fracture
0.955 0.045 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.952 0.048 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.951 0.049 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.949 0.051 0.000
E10.9 Without complications
0.948 0.052 0.000
H40-H42 Glaucoma
0.946 0.054 0.000
H36.0 Diabetic retinopathy
0.946 0.054 0.000
E70-E90 Metabolic disorders
0.945 0.055 0.000
M15-M19 Arthrosis
0.943 0.057 0.000
G90-G99 Other disorders of the nervous system
0.941 0.059 0.000
R21 Rash and other nonspecific skin eruption
0.940 0.060 0.000
M81.9 Osteoporosis, unspecified
0.935 0.065 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.935 0.065 0.000
E83 Disorders of mineral metabolism
0.933 0.067 0.000
E10.3 With ophthalmic complications
0.933 0.067 0.000
M19 Other arthrosis
0.932 0.068 0.000
M47 Spondylosis
0.928 0.072 0.000
M19.9 Arthrosis, unspecified
0.927 0.073 0.000
H53-H54 Visual disturbances and blindness
0.927 0.073 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.925 0.075 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.923 0.077 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.920 0.080 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.919 0.081 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.917 0.083 0.000
H65-H75 Diseases of middle ear and mastoid
0.915 0.085 0.000
Chapter XX External causes of morbidity and mortality
0.911 0.089 0.000
H40 Glaucoma
0.908 0.092 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.908 0.092 0.000
Z50 Care involving use of rehabilitation procedures
0.907 0.093 0.000
H40.9 Glaucoma, unspecified
0.904 0.096 0.000
H34 Retinal vascular occlusions
0.902 0.098 0.000
Z41 Procedures for purposes other than remedying health state
0.899 0.101 0.000
G35 Multiple sclerosis
0.895 0.105 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.892 0.108 0.000
R42 Dizziness and giddiness
0.884 0.116 0.000
Z47 Other orthopaedic follow-up care
0.878 0.122 0.000
Z43 Attention to artificial openings
0.877 0.123 0.000
E83.5 Disorders of calcium metabolism
0.875 0.125 0.000
Z45 Adjustment and management of implanted device
0.872 0.128 0.000
R79 Other abnormal findings of blood chemistry
0.872 0.128 0.000
R87 Abnormal findings in specimens from female genital organs
0.872 0.128 0.000
E11.3 With ophthalmic complications
0.870 0.130 0.000
H65 Nonsuppurative otitis media
0.869 0.131 0.000
M70-M79 Other soft tissue disorders
0.868 0.132 0.000
E11.9 Without complications
0.865 0.135 0.000
G95 Other diseases of spinal cord
0.864 0.136 0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance
0.862 0.138 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.859 0.141 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.858 0.142 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.857 0.143 0.000
E83.3 Disorders of phosphorus metabolism
0.857 0.143 0.000
M47.9 Spondylosis, unspecified
0.853 0.147 0.000
Z42 Follow-up care involving plastic surgery
0.852 0.148 0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.852 0.148 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.846 0.154 0.000
H35 Other retinal disorders
0.845 0.155 0.000
E10.1 With ketoacidosis
0.843 0.157 0.000
E20-E35 Disorders of other endocrine glands
0.841 0.159 0.000
H90-H95 Other disorders of ear
0.839 0.161 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.838 0.162 0.000
H10-H13 Disorders of conjunctiva
0.837 0.163 0.000
H53 Visual disturbances
0.835 0.165 0.000
H55-H59 Other disorders of eye and adnexa
0.834 0.166 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.834 0.166 0.000
R22.1 Localised swelling, mass and lump, neck
0.831 0.169 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.829 0.171 0.000
M47.8 Other spondylosis
0.828 0.172 0.000
Z60 Problems related to social environment
0.825 0.175 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.823 0.177 0.000
H25-H28 Disorders of lens
0.818 0.182 0.000
Chapter XXII Codes for special purposes
0.815 0.185 0.000
M84 Disorders of continuity of bone
0.812 0.188 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.811 0.189 0.000
Z50.5 Speech therapy
0.809 0.191 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.808 0.192 0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device
0.805 0.195 0.000
E10.8 With unspecified complications
0.803 0.197 0.000
R71 Abnormality of red blood cells
0.803 0.197 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.803 0.197 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.800 0.200 0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
0.798 0.202 0.000
H74 Other disorders of middle ear and mastoid
0.797 0.203 0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system
0.796 0.204 0.000
R94.4 Abnormal results of kidney function studies
0.795 0.205 0.000
E83.1 Disorders of iron metabolism
0.795 0.205 0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs
0.791 0.209 0.000
H60-H62 Diseases of external ear
0.790 0.210 0.000
G95.2 Cord compression, unspecified
0.790 0.210 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.789 0.211 0.000
E11.2 With renal complications
0.788 0.212 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.788 0.212 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.786 0.214 0.000
Z45.2 Adjustment and management of vascular access device
0.786 0.214 0.000
H65.3 Chronic mucoid otitis media
0.784 0.216 0.000
R87.6 Abnormal cytological findings
0.782 0.218 0.000
R40 Somnolence, stupor and coma
0.782 0.218 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.780 0.220 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.779 0.221 0.000
H91 Other hearing loss
0.779 0.221 0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract
0.779 0.221 0.000
M82 Osteoporosis in diseases classified elsewhere
0.779 0.221 0.000
H34.8 Other retinal vascular occlusions
0.778 0.222 0.000
E10.5 With peripheral circulatory complications
0.777 0.223 0.000
H54 Blindness and low vision
0.776 0.224 0.000
E10.4 With neurological complications
0.776 0.224 0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
0.775 0.225 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.771 0.229 0.000
H34.2 Other retinal artery occlusions
0.767 0.233 0.000
E10.2 With renal complications
0.766 0.233 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.766 0.234 0.000
R23 Other skin changes
0.765 0.234 0.000
Z60.2 Living alone
0.765 0.235 0.000
R45 Symptoms and signs involving emotional state
0.764 0.236 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.764 0.236 0.000
Z43.2 Attention to ileostomy
0.763 0.237 0.000
R22.4 Localised swelling, mass and lump, lower limb
0.762 0.238 0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity
0.762 0.238 0.000
H35.8 Other specified retinal disorders
0.762 0.238 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.762 0.238 0.000
E88 Other metabolic disorders
0.761 0.239 0.000
G20-G26 Extrapyramidal and movement disorders
0.760 0.240 0.000
Z45.1 Adjustment and management of infusion pump
0.757 0.243 0.000
E40-E46 Malnutrition
0.756 0.243 0.000
R79.9 Abnormal finding of blood chemistry, unspecified
0.756 0.244 0.000
M46 Other inflammatory spondylopathies
0.752 0.248 0.000
M60-M63 Disorders of muscles
0.752 0.248 0.000
E11.1 With ketoacidosis
0.750 0.250 0.000
H50 Other strabismus
0.749 0.251 0.000
R86 Abnormal findings in specimens from male genital organs
0.749 0.251 0.000
Z43.3 Attention to colostomy
0.746 0.254 0.000
M40-M43 Deforming dorsopathies
0.743 0.257 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.743 0.257 0.000
H46 Optic neuritis
0.742 0.258 0.000
M86-M90 Other osteopathies
0.741 0.259 0.000
G81 Hemiplegia
0.740 0.260 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.739 0.261 0.000
Z57 Occupational exposure to risk-factors
0.737 0.263 0.000
H91.9 Hearing loss, unspecified
0.737 0.263 0.000
G30-G32 Other degenerative diseases of the nervous system
0.736 0.264 0.000
H33 Retinal detachments and breaks
0.736 0.264 0.000
R22.0 Localised swelling, mass and lump, head
0.735 0.265 0.000
H10 Conjunctivitis
0.735 0.265 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.734 0.266 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.734 0.266 0.000
H40.5 Glaucoma secondary to other eye disorders
0.733 0.266 0.000
M81.4 Drug-induced osteoporosis
0.730 0.269 0.000
H65.2 Chronic serous otitis media
0.730 0.270 0.000
M47.2 Other spondylosis with radiculopathy
0.728 0.272 0.000
R46 Symptoms and signs involving appearance and behaviour
0.727 0.273 0.000
E73 Lactose intolerance
0.727 0.273 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.726 0.274 0.000
R22.9 Localised swelling, mass and lump, unspecified
0.724 0.276 0.000
H72 Perforation of tympanic membrane
0.722 0.278 0.000
R87.9 Unspecified abnormal finding
0.721 0.279 0.000
E11.4 With neurological complications
0.720 0.279 0.000
W00-W19 Falls
0.720 0.280 0.000
M47.82 Other spondylosis (Cervical region)
0.720 0.280 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
G70-G73 Diseases of myoneural junction and muscle
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.716 0.283 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.716 0.284 0.000
M85 Other disorders of bone density and structure
0.716 0.284 0.000
E13 Other specified diabetes mellitus
0.716 0.284 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.715 0.285 0.000
E10.7 With multiple complications
0.714 0.285 0.000
E10.6 With other specified complications
0.714 0.285 0.000
E10.0 With coma
0.714 0.285 0.000
H69 Other disorders of Eustachian tube
0.714 0.286 0.000
Z63 Other problems related to primary support group, including family circumstances
0.714 0.286 0.000
R40.0 Somnolence
0.713 0.287 0.000
M91-M94 Chondropathies
0.713 0.287 0.000
X60-X84 Intentional self-harm
0.713 0.287 0.000
H52 Disorders of refraction and accommodation
0.713 0.287 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.712 0.287 0.000
H31 Other disorders of choroid
0.712 0.287 0.000
H30 Chorioretinal inflammation
0.712 0.287 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.712 0.288 0.000
V10-V19 Pedal cyclist injured in transport accident
0.712 0.288 0.000
M65-M68 Disorders of synovium and tendon
0.712 0.288 0.000
R94.8 Abnormal results of function studies of other organs and systems
0.711 0.289 0.000
R94.7 Abnormal results of other endocrine function studies
0.711 0.289 0.000
R94.6 Abnormal results of thyroid function studies
0.711 0.289 0.000
R94.2 Abnormal results of pulmonary function studies
0.711 0.289 0.000
R94.1 Abnormal results of function studies of peripheral nervous system and special senses
0.711 0.289 0.000
R94.0 Abnormal results of function studies of central nervous system
0.711 0.289 0.000
E29 Testicular dysfunction
0.708 0.292 0.000
R93.6 Abnormal findings on diagnostic imaging of limbs
0.708 0.292 0.000
Chapter II Neoplasms
0.707 0.293 0.000
D70 Agranulocytosis
0.707 0.293 0.000
Z50.2 Alcohol rehabilitation
0.706 0.294 0.000
H53.2 Diplopia
0.705 0.295 0.000
D68 Other coagulation defects
0.703 0.297 0.000
M19.1 Posttraumatic arthrosis of other joints
0.703 0.297 0.000
M83 Adult osteomalacia
0.702 0.298 0.000
R84 Abnormal findings in specimens from respiratory organs and thorax
0.702 0.298 0.000
H53.0 Amblyopia ex anopsia
0.702 0.298 0.000
H53.4 Visual field defects
0.701 0.299 0.000
M00-M03 Infectious arthropathies
0.700 0.300 0.000
R22.2 Localised swelling, mass and lump, trunk
0.699 0.301 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.699 0.301 0.000
G96 Other disorders of central nervous system
0.699 0.301 0.000
Z47.8 Other specified orthopaedic follow-up care
0.699 0.301 0.000
H57 Other disorders of eye and adnexa
0.699 0.301 0.000
E11.6 With other specified complications
0.698 0.302 0.000
M48 Other spondylopathies
0.698 0.302 0.000
H49 Paralytic strabismus
0.698 0.302 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.698 0.302 0.000
Z46 Fitting and adjustment of other devices
0.697 0.303 0.000
H60 Otitis externa
0.697 0.303 0.000
H35.0 Background retinopathy and retinal vascular changes
0.697 0.303 0.000
Y95 Nosocomial condition
0.696 0.304 0.000
E11.8 With unspecified complications
0.696 0.304 0.000
E11.7 With multiple complications
0.696 0.304 0.000
E11.0 With coma
0.696 0.304 0.000
G95.8 Other specified diseases of spinal cord
0.696 0.304 0.000
Z50.1 Other physical therapy
0.696 0.304 0.000
M79.8 Other specified soft tissue disorders
0.695 0.305 0.000
G37 Other demyelinating diseases of central nervous system
0.695 0.305 0.000
Z54 Convalescence
0.695 0.305 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.692 0.307 0.000
M19.98 Arthrosis, unspecified (Other)
0.690 0.310 0.000
H40.8 Other glaucoma
0.690 0.310 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.690 0.310 0.000
Z43.6 Attention to other artificial openings of urinary tract
0.690 0.310 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.689 0.311 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.689 0.311 0.000
M76 Enthesopathies of lower limb, excluding foot
0.689 0.311 0.000
E14 Unspecified diabetes mellitus
0.688 0.312 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.688 0.312 0.000
E83.4 Disorders of magnesium metabolism
0.688 0.312 0.000
Z58 Problems related to physical environment
0.688 0.312 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.687 0.313 0.000
M49 Spondylopathies in diseases classified elsewhere
0.687 0.313 0.000
H27 Other disorders of lens
0.687 0.313 0.000
M81.8 Other osteoporosis
0.685 0.315 0.000
M81.6 Localised osteoporosis [Lequesne]
0.685 0.315 0.000
M81.5 Idiopathic osteoporosis
0.685 0.315 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.685 0.315 0.000
M81.2 Osteoporosis of disuse
0.685 0.315 0.000
M81.1 Postoophorectomy osteoporosis
0.685 0.315 0.000
M81.0 Postmenopausal osteoporosis
0.685 0.315 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.683 0.317 0.000
Z44 Fitting and adjustment of external prosthetic device
0.683 0.317 0.000
R43 Disturbances of smell and taste
0.682 0.318 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.682 0.318 0.000
R89 Abnormal findings in specimens from other organs, systems and tissues
0.680 0.320 0.000
R83 Abnormal findings in cerebrospinal fluid
0.680 0.320 0.000
D73 Diseases of spleen
0.680 0.320 0.000
H53.9 Visual disturbance, unspecified
0.679 0.321 0.000
E11.5 With peripheral circulatory complications
0.679 0.321 0.000
H42 Glaucoma in diseases classified elsewhere
0.678 0.322 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.678 0.322 0.000
G62 Other polyneuropathies
0.678 0.322 0.000
E85 Amyloidosis
0.677 0.323 0.000
E84 Cystic fibrosis
0.677 0.323 0.000
E79 Disorders of purine and pyrimidine metabolism
0.677 0.323 0.000
E77 Disorders of glycoprotein metabolism
0.677 0.323 0.000
E76 Disorders of glycosaminoglycan metabolism
0.677 0.323 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.677 0.323 0.000
E74 Other disorders of carbohydrate metabolism
0.677 0.323 0.000
E72 Other disorders of amino-acid metabolism
0.677 0.323 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.677 0.323 0.000
E70 Disorders of aromatic amino-acid metabolism
0.677 0.323 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.677 0.323 0.000
Z50.8 Care involving use of rehabilitation procedures
0.677 0.323 0.000
M15 Polyarthrosis
0.676 0.324 0.000
M18 Arthrosis of first carpometacarpal joint
0.675 0.325 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.675 0.325 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.675 0.325 0.000
G90 Disorders of autonomic nervous system
0.675 0.325 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.675 0.325 0.000
G92 Toxic encephalopathy
0.675 0.325 0.000
E50-E64 Other nutritional deficiencies
0.675 0.325 0.000
Q00-Q07 Congenital malformations of the nervous system
0.674 0.326 0.000
M47.1 Other spondylosis with myelopathy
0.672 0.327 0.000
H35.2 Other proliferative retinopathy
0.671 0.329 0.000
G81.9 Hemiplegia, unspecified
0.670 0.330 0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.670 0.330 0.000
M81.96 Osteoporosis, unspecified (Lower leg)
0.670 0.330 0.000
M81.94 Osteoporosis, unspecified (Hand)
0.670 0.330 0.000
M81.93 Osteoporosis, unspecified (Forearm)
0.670 0.330 0.000
M81.92 Osteoporosis, unspecified (Upper arm)
0.670 0.330 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.670 0.330 0.000
G36 Other acute disseminated demyelination
0.670 0.330 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.669 0.331 0.000
E83.8 Other disorders of mineral metabolism
0.669 0.331 0.000
E83.2 Disorders of zinc metabolism
0.669 0.331 0.000
E83.0 Disorders of copper metabolism
0.669 0.331 0.000
E27 Other disorders of adrenal gland
0.669 0.331 0.000
M19.8 Other specified arthrosis
0.668 0.331 0.000
M19.2 Other secondary arthrosis
0.668 0.331 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.666 0.333 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.666 0.334 0.000
H74.8 Other specified disorders of middle ear and mastoid
0.665 0.335 0.000
M50-M54 Other dorsopathies
0.665 0.335 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.665 0.335 0.000
H54.0 Blindness, both eyes
0.664 0.336 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.663 0.337 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.663 0.337 0.000
O60-O75 Complications of labour and delivery
0.663 0.337 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.662 0.338 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.662 0.338 0.000
H10.9 Conjunctivitis, unspecified
0.662 0.338 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.662 0.338 0.000
S60-S69 Injuries to the wrist and hand
0.661 0.339 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.660 0.340 0.000
R22.7 Localised swelling, mass and lump, multiple sites
0.659 0.341 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.657 0.343 0.000
R77 Other abnormalities of plasma proteins
0.657 0.343 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.657 0.343 0.000
R94.3 Abnormal results of cardiovascular function studies
0.657 0.343 0.000
D75 Other diseases of blood and blood-forming organs
0.657 0.343 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.656 0.344 0.000
H70 Mastoiditis and related conditions
0.656 0.344 0.000
H68 Eustachian salpingitis and obstruction
0.656 0.344 0.000
H67 Otitis media in diseases classified elsewhere
0.656 0.344 0.000
H55 Nystagmus and other irregular eye movements
0.655 0.345 0.000
M71 Other bursopathies
0.654 0.346 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.653 0.346 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.654 0.346 0.000
Y35-Y36 Legal intervention and operations of war
0.653 0.347 0.000
Y10-Y34 Event of undetermined intent
0.653 0.347 0.000
Y00-Y09 Assault
0.653 0.347 0.000
X85-X99 Assault
0.653 0.347 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.653 0.347 0.000
X50-X57 Overexertion, travel and privation
0.653 0.347 0.000
X30-X39 Exposure to forces of nature
0.653 0.347 0.000
X20-X29 Contact with venomous animals and plants
0.653 0.347 0.000
X10-X19 Contact with heat and hot substances
0.653 0.347 0.000
X00-X09 Exposure to smoke, fire and flames
0.653 0.347 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.653 0.347 0.000
W75-W84 Other accidental threats to breathing
0.653 0.347 0.000
W65-W74 Accidental drowning and submersion
0.653 0.347 0.000
W50-W64 Exposure to animate mechanical forces
0.653 0.347 0.000
V98-V99 Other and unspecified transport accidents
0.653 0.347 0.000
V95-V97 Air and space transport accidents
0.653 0.347 0.000
V90-V94 Water transport accidents
0.653 0.347 0.000
V70-V79 Bus occupant injured in transport accident
0.653 0.347 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.653 0.347 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.653 0.347 0.000
V40-V49 Car occupant injured in transport accident
0.653 0.347 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.653 0.347 0.000
V01-V09 Pedestrian injured in transport accident
0.653 0.347 0.000
H50.9 Strabismus, unspecified
0.653 0.347 0.000
H74.4 Polyp of middle ear
0.652 0.348 0.000
H40.6 Glaucoma secondary to drugs
0.651 0.349 0.000
H40.4 Glaucoma secondary to eye inflammation
0.651 0.349 0.000
H40.3 Glaucoma secondary to eye trauma
0.651 0.349 0.000
Z65 Problems related to other psychosocial circumstances
0.651 0.349 0.000
Z64 Problems related to certain psychosocial circumstances
0.651 0.349 0.000
Z62 Other problems related to upbringing
0.651 0.349 0.000
Z61 Problems related to negative life events in childhood
0.651 0.349 0.000
Z59 Problems related to housing and economic circumstances
0.651 0.349 0.000
Z56 Problems related to employment and unemployment
0.651 0.349 0.000
Z55 Problems related to education and literacy
0.651 0.349 0.000
Z50.6 Orthoptic training
0.650 0.349 0.000
Z50.3 Drug rehabilitation
0.650 0.349 0.000
M79.1 Myalgia
0.650 0.350 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.649 0.351 0.000
R44.3 Hallucinations, unspecified
0.647 0.353 0.000
H34.9 Retinal vascular occlusion, unspecified
0.647 0.353 0.000
H34.1 Central retinal artery occlusion
0.647 0.353 0.000
H34.0 Transient retinal artery occlusion
0.647 0.353 0.000
V80-V89 Other land transport accidents
0.646 0.354 0.000
G91 Hydrocephalus
0.645 0.355 0.000
Z41.9 Procedures for purposes other than remedying health state, unspecified
0.645 0.355 0.000
Z41.8 Other procedures for purposes other than remedying health state
0.645 0.355 0.000
Z41.3 Ear piercing
0.645 0.355 0.000
Z41.2 Routine and ritual circumcision
0.645 0.355 0.000
Z41.0 Hair transplant
0.645 0.355 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.644 0.356 0.000
C64-C68 Malignant neoplasms of urinary tract
0.641 0.359 0.000
Z52 Donors of organs and tissues
0.641 0.359 0.000
H90 Conductive and sensorineural hearing loss
0.641 0.359 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.640 0.360 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.640 0.360 0.000
H51 Other disorders of binocular movement
0.639 0.361 0.000
H26 Other cataract
0.639 0.361 0.000
M79.7 Fibromyalgia
0.639 0.361 0.000
H54.7 Unspecified visual loss
0.638 0.362 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.637 0.363 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.637 0.363 0.000
H43-H45 Disorders of vitreous body and globe
0.637 0.363 0.000
M82.1 Osteoporosis in endocrine disorders
0.635 0.365 0.000
O85-O92 Complications predominantly related to the puerperium
0.634 0.366 0.000
E22 Hyperfunction of pituitary gland
0.634 0.366 0.000
V20-V29 Motorcycle rider injured in transport accident
0.634 0.366 0.000
R47-R49 Symptoms and signs involving speech and voice
0.634 0.366 0.000
Z57.2 Occupational exposure to dust
0.632 0.368 0.000
H60.9 Otitis externa, unspecified
0.631 0.369 0.000
M84.0 Malunion of fracture
0.631 0.369 0.000
M47.89 Other spondylosis (Site unspecified)
0.631 0.369 0.000
Z47.9 Orthopaedic follow-up care, unspecified
0.630 0.370 0.000
E34 Other endocrine disorders
0.630 0.370 0.000
R26 Abnormalities of gait and mobility
0.629 0.371 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.629 0.371 0.000
Z43.9 Attention to unspecified artificial opening
0.629 0.371 0.000
Z43.8 Attention to other artificial openings
0.629 0.371 0.000
Z43.7 Attention to artificial vagina
0.629 0.371 0.000
Z43.5 Attention to cyctostomy
0.629 0.371 0.000
Z43.4 Attention to other artificial openings of digestive tract
0.629 0.371 0.000
Z43.0 Attention to tracheostomy
0.629 0.371 0.000
R85.5 Abnormal microbiological findings
0.629 0.371 0.000
H35.9 Retinal disorder, unspecified
0.628 0.372 0.000
M84.4 Pathological fracture, not elsewhere classified
0.627 0.373 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.627 0.373 0.000
M20-M25 Other joint disorders
0.627 0.373 0.000
Z45.9 Adjustment and management of unspecified implanted device
0.625 0.374 0.000
Z45.3 Adjustment and management of implanted hearing device
0.625 0.374 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.625 0.374 0.000
R87.8 Other abnormal findings
0.625 0.375 0.000
R87.7 Abnormal histological findings
0.625 0.375 0.000
R87.5 Abnormal microbiological findings
0.625 0.375 0.000
R87.4 Abnormal immunological findings
0.625 0.375 0.000
R87.3 Abnormal level of substances chiefly nonmedicinal as to source
0.625 0.375 0.000
R87.2 Abnormal level of other drugs, medicaments and biological substances
0.625 0.375 0.000
R87.1 Abnormal level of hormones
0.625 0.375 0.000
R87.0 Abnormal level of enzymes
0.625 0.375 0.000
R23.0 Cyanosis
0.625 0.375 0.000
H65.4 Other chronic nonsuppurative otitis media
0.623 0.377 0.000
H65.1 Other acute nonsuppurative otitis media
0.623 0.377 0.000
H65.0 Acute serous otitis media
0.623 0.377 0.000
C34 Malignant neoplasm of bronchus and lung
0.623 0.377 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.623 0.377 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.621 0.378 0.000
M47.86 Other spondylosis (Lumbar region)
0.620 0.380 0.000
D68.8 Other specified coagulation defects
0.620 0.380 0.000
G95.1 Vascular myelopathies
0.619 0.380 0.000
G95.0 Syringomyelia and syringobulbia
0.619 0.380 0.000
H73 Other disorders of tympanic membrane
0.619 0.381 0.000
Q80-Q89 Other congenital malformations
0.619 0.381 0.000
O80-O84 Delivery
0.619 0.381 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.618 0.381 0.000
G25 Other extrapyramidal and movement disorders
0.617 0.383 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.617 0.383 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.617 0.383 0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere
0.616 0.384 0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere
0.616 0.384 0.000
G82 Paraplegia and tetraplegia
0.615 0.385 0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.614 0.385 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.613 0.386 0.000
E29.1 Testicular hypofunction
0.613 0.387 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.612 0.388 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.612 0.388 0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)
0.611 0.388 0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)
0.611 0.388 0.000
M47.94 Spondylosis, unspecified (Thoracic region)
0.611 0.388 0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)
0.611 0.388 0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)
0.611 0.388 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.611 0.388 0.000
H35.6 Retinal haemorrhage
0.611 0.389 0.000
D55-D59 Haemolytic anaemias
0.611 0.389 0.000
Z42.9 Follow-up care involving plastic surgery, unspecified
0.611 0.389 0.000
Z42.8 Follow-up care involving plastic surgery of other body part
0.611 0.389 0.000
Z42.4 Follow-up care involving plastic surgery of lower extremity
0.611 0.389 0.000
Z42.3 Follow-up care involving plastic surgery of upper extremity
0.611 0.389 0.000
Z42.2 Follow-up care involving plastic surgery of other parts of trunk
0.611 0.389 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.610 0.390 0.000
Y52 Agents primarily affecting the cardiovascular system
0.609 0.391 0.000
Q60-Q64 Congenital malformations of the urinary system
0.607 0.393 0.000
M72 Fibroblastic disorders
0.607 0.393 0.000
H35.7 Separation of retinal layers
0.606 0.394 0.000
H35.5 Hereditary retinal dystrophy
0.606 0.394 0.000
H35.1 Retinopathy of prematurity
0.606 0.394 0.000
R86.8 Other abnormal findings
0.605 0.394 0.000
Q50-Q56 Congenital malformations of genital organs
0.604 0.396 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.604 0.396 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.603 0.397 0.000
E32 Diseases of thymus
0.603 0.397 0.000
E31 Polyglandular dysfunction
0.603 0.397 0.000
E30 Disorders of puberty, not elsewhere classified
0.603 0.397 0.000
E26 Hyperaldosteronism
0.603 0.397 0.000
E25 Adrenogenital disorders
0.603 0.397 0.000
E24 Cushing's syndrome
0.603 0.397 0.000
E20 Hypoparathyroidism
0.603 0.397 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.603 0.397 0.000
R76 Other abnormal immunological findings in serum
0.603 0.397 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.601 0.398 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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