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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2844555
log Bayes Factor = 95.7037
Chromosome 6   position 31,341,379  (GRCh37) Explore rs2844555 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
M45.X9 Ankylosing spondylitis (Site unspecified)
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E14.9 Without complications
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E20-E35 Disorders of other endocrine glands
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
E03 Other hypothyroidism
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E27 Other disorders of adrenal gland
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.001 0.999
E05.9 Thyrotoxicosis, unspecified
0.000 0.001 0.999
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.002 0.998
E16 Other disorders of pancreatic internal secretion
0.000 0.003 0.997
E27.1 Primary adrenocortical insufficiency
0.000 0.003 0.997
E16.2 Hypoglycaemia, unspecified
0.000 0.004 0.996
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.007 0.993
M45 Ankylosing spondylitis
0.989 0.011 0.000
K51 Ulcerative colitis
0.986 0.014 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.986 0.014 0.000
E10.4 With neurological complications
0.000 0.016 0.984
E11.9 Without complications
0.000 0.017 0.983
K51.9 Ulcerative colitis, unspecified
0.980 0.020 0.000
E11.3 With ophthalmic complications
0.000 0.030 0.970
K51.2 Ulcerative (chronic) proctitis
0.968 0.032 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.958 0.042 0.000
J45.9 Asthma, unspecified
0.000 0.043 0.957
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.046 0.954
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.051 0.949
E11.1 With ketoacidosis
0.000 0.055 0.945
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.061 0.939
K51.4 Pseudopolyposis of colon
0.936 0.064 0.000
E10.0 With coma
0.000 0.069 0.931
E11.5 With peripheral circulatory complications
0.000 0.074 0.926
E22 Hyperfunction of pituitary gland
0.000 0.082 0.918
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.089 0.911
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.118 0.882
E10.8 With unspecified complications
0.000 0.118 0.882
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.121 0.879
K51.5 Mucosal proctocolitis
0.876 0.124 0.000
E23 Hypofunction and other disorders of pituitary gland
0.000 0.126 0.874
E10.2 With renal complications
0.000 0.131 0.869
E11.0 With coma
0.000 0.136 0.864
E14.1 With ketoacidosis
0.000 0.138 0.862
K50-K52 Noninfective enteritis and colitis
0.860 0.140 0.000
E27.9 Disorder of adrenal gland, unspecified
0.000 0.151 0.849
K50 Crohn's disease [regional enteritis]
0.849 0.151 0.000
E10.5 With peripheral circulatory complications
0.000 0.165 0.835
K50.9 Crohn's disease, unspecified
0.834 0.166 0.000
E22.0 Acromegaly and pituitary gigantism
0.000 0.174 0.826
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.177 0.823
E10.6 With other specified complications
0.000 0.184 0.816
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.185 0.815
E14.8 With unspecified complications
0.000 0.185 0.815
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.188 0.812
E07 Other disorders of thyroid
0.000 0.192 0.808
K51.8 Other ulcerative colitis
0.801 0.199 0.000
G35 Multiple sclerosis
0.798 0.202 0.000
E14.6 With other specified complications
0.000 0.221 0.779
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.221 0.779
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.223 0.777
E14.3 With ophthalmic complications
0.000 0.225 0.775
E28 Ovarian dysfunction
0.000 0.225 0.775
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.775 0.225 0.000
E23.2 Diabetes insipidus
0.000 0.226 0.774
E20 Hypoparathyroidism
0.000 0.232 0.768
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.239 0.761
E10.7 With multiple complications
0.000 0.244 0.756
E23.7 Disorder of pituitary gland, unspecified
0.000 0.244 0.756
E25 Adrenogenital disorders
0.000 0.249 0.751
M45.X6 Ankylosing spondylitis (Lumbar region)
0.735 0.265 0.000
E27.2 Addisonian crisis
0.000 0.269 0.731
K50.0 Crohn's disease of small intestine
0.728 0.272 0.000
E40-E46 Malnutrition
0.000 0.276 0.724
E14.5 With peripheral circulatory complications
0.000 0.277 0.722
E07.8 Other specified disorders of thyroid
0.000 0.279 0.721
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.283 0.717
E32 Diseases of thymus
0.000 0.283 0.717
E30 Disorders of puberty, not elsewhere classified
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E27.5 Adrenomedullary hyperfunction
0.000 0.283 0.717
E27.0 Other adrenocortical overactivity
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.284 0.716
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.285 0.715
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.285 0.715
E16.4 Abnormal secretion of gastrin
0.000 0.285 0.715
E16.3 Increased secretion of glucagon
0.000 0.285 0.715
E26 Hyperaldosteronism
0.000 0.289 0.711
E31 Polyglandular dysfunction
0.000 0.291 0.709
E16.1 Other hypoglycaemia
0.000 0.291 0.709
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.709 0.291 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.709 0.291 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.709 0.291 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.709 0.291 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.709 0.291 0.000
E14.2 Withrenal complications
0.000 0.294 0.706
E13 Other specified diabetes mellitus
0.000 0.305 0.695
K50.1 Crohn's disease of large intestine
0.695 0.305 0.000
E03.1 Congenital hypothyroidism without goitre
0.000 0.313 0.687
M06 Other rheumatoid arthritis
0.000 0.313 0.687
E23.6 Other disorders of pituitary gland
0.000 0.326 0.674
M45.X2 Ankylosing spondylitis (Cervical region)
0.674 0.326 0.000
E06 Thyroiditis
0.000 0.328 0.672
E11.6 With other specified complications
0.000 0.328 0.672
E24 Cushing's syndrome
0.000 0.336 0.664
E11.2 With renal complications
0.000 0.337 0.663
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.339 0.661
E14.4 With neurological complications
0.000 0.341 0.659
E22.8 Other hyperfunction of pituitary gland
0.000 0.342 0.658
M06.3 Rheumatoid nodule
0.000 0.343 0.657
E34 Other endocrine disorders
0.000 0.343 0.657
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.348 0.652
G35-G37 Demyelinating diseases of the central nervous system
0.647 0.353 0.000
E27.8 Other specified disorders of adrenal gland
0.000 0.353 0.647
E05.8 Other thyrotoxicosis
0.000 0.354 0.646
E22.1 Hyperprolactinaemia
0.000 0.360 0.640
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.367 0.633
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.369 0.631
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.373 0.627
E23.1 Drug-induced hypopituitarism
0.000 0.373 0.627
E29 Testicular dysfunction
0.000 0.381 0.619
E03.8 Other specified hypothyroidism
0.000 0.382 0.618
K90 Intestinal malabsorption
0.000 0.382 0.618
K51.1 Ulcerative (chronic) ileocolitis
0.616 0.383 0.000
G37 Other demyelinating diseases of central nervous system
0.614 0.386 0.000
E28.2 Polycystic ovarian syndrome
0.000 0.393 0.607
E20.9 Hypoparathyroidism, unspecified
0.000 0.399 0.601
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.401 0.599
E11.8 With unspecified complications
0.000 0.408 0.592
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.410 0.590
M06.34 Rheumatoid nodule (Hand)
0.000 0.415 0.585
G37.9 Demyelinating disease of central nervous system, unspecified
0.584 0.416 0.000
E07.1 Dyshormogenetic goitre
0.000 0.421 0.579
E07.0 Hypersecretion of calcitonin
0.000 0.421 0.579
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.428 0.572
E11.4 With neurological complications
0.000 0.430 0.570
E28.3 Primary ovarian failure
0.000 0.435 0.565
E28.9 Ovarian dysfunction, unspecified
0.000 0.444 0.556
E28.8 Other ovarian dysfunction
0.000 0.444 0.556
E28.1 Androgen excess
0.000 0.444 0.556
E28.0 Oestrogen excess
0.000 0.444 0.556
E26.9 Hyperaldosteronism, unspecified
0.000 0.449 0.551
E20.8 Other hypoparathyroidism
0.000 0.449 0.550
E20.1 Pseudohypoparathyroidism
0.000 0.449 0.550
E20.0 Idiopathic hypoparathyroidism
0.000 0.449 0.550
E06.3 Autoimmune thyroiditis
0.000 0.459 0.541
E25.9 Adrenogenital disorder, unspecified
0.000 0.461 0.538
E25.8 Other adrenogenital disorders
0.000 0.461 0.538
E21.3 Hyperparathyroidism, unspecified
0.000 0.470 0.530
E46 Unspecified protein-energy malnutrition
0.000 0.473 0.527
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.474 0.526
E24.0 Pituitary-dependent Cushing's disease
0.000 0.474 0.526
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.481 0.519
E45 Retarded development following protein-energy malnutrition
0.000 0.481 0.519
E43 Unspecified severe protein-energy malnutrition
0.000 0.481 0.519
E42 Marasmic kwashiorkor
0.000 0.481 0.519
E41 Nutritional marasmus
0.000 0.481 0.519
E40 Kwashiorkor
0.000 0.481 0.519
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E30.9 Disorder of puberty, unspecified
0.000 0.486 0.514
E30.8 Other disorders of puberty
0.000 0.486 0.514
E30.1 Precocious puberty
0.000 0.486 0.514
E30.0 Delayed puberty
0.000 0.486 0.514
E32.9 Disease of thymus, unspecified
0.000 0.486 0.514
E32.8 Other diseases of thymus
0.000 0.486 0.514
E32.1 Abscess of thymus
0.000 0.486 0.514
E32.0 Persistent hyperplasia of thymus
0.000 0.486 0.514
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.486 0.514
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.486 0.514
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.486 0.514
M06.8 Other specified rheumatoid arthritis
0.000 0.488 0.512
E26.8 Other hyperaldosteronism
0.000 0.490 0.510
E26.1 Secondary hyperaldosteronism
0.000 0.490 0.510
E31.9 Polyglandular dysfunction, unspecified
0.000 0.491 0.509
E31.8 Other polyglandular dysfunction
0.000 0.491 0.509
E31.1 Polyglandular hyperfunction
0.000 0.491 0.509
K51.0 Ulcerative (chronic) enterocolitis
0.507 0.493 0.000
E24.2 Drug-induced Cushing's syndrome
0.000 0.494 0.506
K90.8 Other intestinal malabsorption
0.000 0.494 0.506
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.502 0.498 0.000
E31.0 Autoimmune polyglandular failure
0.000 0.499 0.501
E13.8 With unspecified complications
0.000 0.501 0.499
E13.7 With multiple complications
0.000 0.501 0.499
E13.6 With other specified complications
0.000 0.501 0.499
E13.5 With peripheral circulatory complications
0.000 0.501 0.499
E13.4 With neurological complications
0.000 0.501 0.499
E13.2 With renal complications
0.000 0.501 0.499
E13.1 With ketoacidosis
0.000 0.501 0.499
E13.0 With coma
0.000 0.501 0.499
E34.9 Endocrine disorder, unspecified
0.000 0.503 0.497
E13.9 Without complications
0.000 0.505 0.495
E21.4 Other specified disorders of parathyroid gland
0.000 0.506 0.494
M06.2 Rheumatoid bursitis
0.000 0.507 0.493
M06.1 Adult-onset Still's disease
0.000 0.507 0.493
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.510 0.490
K90.9 Intestinal malabsorption, unspecified
0.000 0.512 0.488
E06.4 Drug-induced thyroiditis
0.000 0.518 0.482
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.518 0.482
E06.0 Acute thyroiditis
0.000 0.518 0.482
E13.3 With ophthalmic complications
0.000 0.519 0.481
G36 Other acute disseminated demyelination
0.478 0.522 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.524 0.476
E24.3 Ectopic ACTH syndrome
0.000 0.524 0.476
E24.1 Nelson's syndrome
0.000 0.524 0.476
E06.1 Subacute thyroiditis
0.000 0.527 0.473
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.529 0.471
M06.38 Rheumatoid nodule (Other)
0.000 0.529 0.471
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.529 0.471
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.529 0.471
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.529 0.471
E34.5 Androgen resistance syndrome
0.000 0.529 0.471
E34.4 Constitutional tall stature
0.000 0.529 0.471
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.529 0.471
E34.1 Other hypersecretion of intestinal hormones
0.000 0.529 0.471
E34.8 Other specified endocrine disorders
0.000 0.530 0.470
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.530 0.469
E65-E68 Obesity and other hyperalimentation
0.000 0.531 0.469
E24.8 Other Cushing's syndrome
0.000 0.531 0.468
E06.5 Other chronic thyroiditis
0.000 0.537 0.463
D64.9 Anaemia, unspecified
0.000 0.540 0.460
E26.0 Primary hyperaldosteronism
0.000 0.549 0.451
E07.9 Disorder of thyroid, unspecified
0.000 0.556 0.444
E29.8 Other testicular dysfunction
0.000 0.556 0.444
E29.0 Testicular hyperfunction
0.000 0.556 0.444
K90.3 Pancreatic steatorrhoea
0.000 0.557 0.443
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.557 0.443
K90.1 Tropical sprue
0.000 0.557 0.443
M06.4 Inflammatory polyarthropathy
0.000 0.557 0.443
G37.5 Concentric sclerosis [Balo]
0.440 0.560 0.000
G37.4 Subacute necrotising myelitis
0.440 0.560 0.000
G37.2 Central pontine myelinolysis
0.440 0.560 0.000
G37.1 Central demyelination of corpus callosum
0.440 0.560 0.000
G37.0 Diffuse sclerosis
0.440 0.560 0.000
K50.8 Other Crohn's disease
0.440 0.560 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.569 0.431
E34.0 Carcinoid syndrome
0.000 0.570 0.430
E34.3 Short stature, not elsewhere classified
0.000 0.576 0.424
E29.9 Testicular dysfunction, unspecified
0.000 0.580 0.420
E21.2 Other hyperparathyroidism
0.000 0.586 0.414
M06.33 Rheumatoid nodule (Forearm)
0.000 0.588 0.412
G37.8 Other specified demyelinating diseases of central nervous system
0.405 0.595 0.000
H36.0 Diabetic retinopathy
0.000 0.601 0.399
E21.0 Primary hyperparathyroidism
0.000 0.605 0.395
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.613 0.387
E70-E90 Metabolic disorders
0.001 0.614 0.386
E29.1 Testicular hypofunction
0.000 0.621 0.379
E06.9 Thyroiditis, unspecified
0.000 0.623 0.376
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.627 0.373
E44.1 Mild protein-energy malnutrition
0.000 0.627 0.372
E44.0 Moderate protein-energy malnutrition
0.000 0.627 0.372
E50-E64 Other nutritional deficiencies
0.000 0.629 0.371
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.632 0.367
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.632 0.367
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.632 0.367
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.632 0.367
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.632 0.367
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.632 0.367
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.632 0.367
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.632 0.367
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.632 0.367
E74 Other disorders of carbohydrate metabolism
0.000 0.642 0.357
G36.0 Neuromyelitis optica [Devic]
0.357 0.643 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.645 0.355
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.647 0.353
M06.18 Adult-onset Still's disease (Other)
0.000 0.647 0.353
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.647 0.353
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.647 0.353
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.647 0.353
M06.14 Adult-onset Still's disease (Hand)
0.000 0.647 0.353
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.647 0.353
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.647 0.353
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.647 0.353
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.647 0.353
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.647 0.353
M06.28 Rheumatoid bursitis (Other)
0.000 0.647 0.353
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.647 0.353
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.647 0.353
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.647 0.353
M06.24 Rheumatoid bursitis (Hand)
0.000 0.647 0.353
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.647 0.353
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.647 0.353
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.647 0.353
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.647 0.353
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.655 0.344
G36.9 Acute disseminated demyelination, unspecified
0.343 0.657 0.000
G36.8 Other specified acute disseminated demyelination
0.343 0.657 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.343 0.657 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.659 0.341
E67 Other hyperalimentation
0.000 0.664 0.336
E68 Sequelae of hyperalimentation
0.000 0.664 0.336
K75.4 Autoimmune hepatitis
0.000 0.664 0.336
E65 Localised adiposity
0.000 0.668 0.332
E78.2 Mixed hyperlipidaemia
0.000 0.670 0.330
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.674 0.326
K75 Other inflammatory liver diseases
0.000 0.677 0.323
K52 Other non-infective gastro-enteritis and colitis
0.318 0.682 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.682 0.318
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.682 0.318
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.682 0.318
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.682 0.318
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.682 0.318
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.682 0.318
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.682 0.318
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.686 0.314
K74 Fibrosis and cirrhosis of liver
0.000 0.688 0.312
K70-K77 Diseases of liver
0.000 0.689 0.311
E78.8 Other disorders of lipoprotein metabolism
0.000 0.692 0.308
E89.3 Postprocedural hypopituitarism
0.000 0.694 0.306
E51 Thiamine deficiency
0.000 0.698 0.302
K73 Chronic hepatitis, not elsewhere classified
0.000 0.701 0.299
K74.3 Primary biliary cirrhosis
0.000 0.702 0.298
K75.8 Other specified inflammatory liver diseases
0.000 0.705 0.295
E23.0 Hypopituitarism
0.000 0.707 0.293
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.293 0.707 0.000
E24.9 Cushing's syndrome, unspecified
0.000 0.712 0.288
H20.9 Iridocyclitis, unspecified
0.288 0.712 0.000
E78.6 Lipoprotein deficiency
0.000 0.713 0.287
E78.1 Pure hyperglyceridaemia
0.000 0.713 0.287
E79 Disorders of purine and pyrimidine metabolism
0.001 0.714 0.286
K74.5 Biliary cirrhosis, unspecified
0.000 0.716 0.284
J45 Asthma
0.000 0.717 0.283
K52.3 Indeterminate colitis
0.281 0.719 0.000
K73.9 Chronic hepatitis, unspecified
0.000 0.720 0.280
E77 Disorders of glycoprotein metabolism
0.001 0.723 0.277
E76 Disorders of glycosaminoglycan metabolism
0.001 0.723 0.277
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.001 0.723 0.277
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.001 0.723 0.277
K74.6 Other and unspecified cirrhosis of liver
0.000 0.724 0.276
I83 Varicose veins of lower extremities
0.275 0.725 0.000
E88 Other metabolic disorders
0.000 0.725 0.274
E84 Cystic fibrosis
0.001 0.726 0.274
E70 Disorders of aromatic amino-acid metabolism
0.001 0.727 0.272
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.731 0.269
E78.4 Other hyperlipidaemia
0.000 0.731 0.268
I83.0 Varicose veins of lower extremities with ulcer
0.266 0.734 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.734 0.266
E63 Other nutritional deficiencies
0.000 0.734 0.266
E50 Vitamin A deficiency
0.000 0.734 0.266
E60 Dietary zinc deficiency
0.000 0.734 0.266
E59 Dietary selenium deficiency
0.000 0.734 0.266
E54 Ascorbic acid deficiency
0.000 0.734 0.266
E52 Niacin deficiency [pellagra]
0.000 0.734 0.266
E58 Dietary calcium deficiency
0.000 0.737 0.263
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.739 0.261
E56 Other vitamin deficiencies
0.000 0.740 0.260
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.742 0.258
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.743 0.256
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.743 0.256
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.743 0.256
E74.2 Disorders of galactose metabolism
0.000 0.743 0.256
E74.1 Disorders of fructose metabolism
0.000 0.743 0.256
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.747 0.253
E51.2 Wernicke's encephalopathy
0.000 0.747 0.253
E73 Lactose intolerance
0.001 0.750 0.250
K72 Hepatic failure, not elsewhere classified
0.000 0.750 0.250
E78.0 Pure hypercholesterolaemia
0.000 0.752 0.248
K52.0 Gastro-enteritis and colitis due to radiation
0.246 0.754 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.245 0.755 0.000
E72 Other disorders of amino-acid metabolism
0.001 0.757 0.243
D64 Other anaemias
0.000 0.757 0.243
E67.8 Other specified hyperalimentation
0.000 0.759 0.241
E67.3 Hypervitaminosis D
0.000 0.759 0.241
E67.2 Megavitamin-B6 syndrome
0.000 0.759 0.241
E67.1 Hypercarotenaemia
0.000 0.759 0.241
E67.0 Hypervitaminosis A
0.000 0.759 0.241
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.762 0.238
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.766 0.234
E89.5 Postprocedural testicular hypofunction
0.000 0.766 0.234
E89.1 Postprocedural hypoinsulinaemia
0.000 0.766 0.234
E74.0 Glycogen storage disease
0.001 0.768 0.232
K75.2 Nonspecific reactive hepatitis
0.000 0.768 0.232
K75.1 Phlebitis of portal vein
0.000 0.768 0.232
E89.0 Postprocedural hypothyroidism
0.000 0.769 0.231
K74.1 Hepatic sclerosis
0.000 0.770 0.230
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.227 0.773 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.773 0.227
K74.4 Secondary biliary cirrhosis
0.000 0.776 0.224
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.776 0.224
K52.1 Toxic gastro-enteritis and colitis
0.223 0.777 0.000
K77 Liver disorders in diseases classified elsewhere
0.000 0.777 0.223
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.777 0.222
K72.9 Hepatic failure, unspecified
0.000 0.778 0.222
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.001 0.778 0.221
H20 Iridocyclitis
0.221 0.779 0.000
E51.9 Thiamine deficiency, unspecified
0.000 0.783 0.217
E51.8 Other manifestations of thiamine deficiency
0.000 0.783 0.217
E51.1 Beriberi
0.000 0.783 0.217
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.785 0.214
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.785 0.215
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.785 0.215
K74.0 Hepatic fibrosis
0.000 0.786 0.214
M05-M14 Inflammatory polyarthropathies
0.000 0.786 0.214
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.787 0.213
E61 Deficiency of other nutrient elements
0.000 0.789 0.211
K71 Toxic liver disease
0.000 0.791 0.209
E89.4 Postprocedural ovarian failure
0.000 0.792 0.208
J45.1 Nonallergic asthma
0.000 0.792 0.208
M05 Seropositive rheumatoid arthritis
0.000 0.793 0.207
E88.2 Lipomatosis, not elsewhere classified
0.000 0.794 0.206
E78.3 Hyperchylomicronaemia
0.000 0.794 0.206
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.001 0.794 0.205
E79.8 Other disorders of purine and pyrimidine metabolism
0.001 0.794 0.205
E79.1 Lesch-Nyhan syndrome
0.001 0.794 0.205
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.796 0.204
J45.8 Mixed asthma
0.000 0.797 0.202
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.798 0.202
H36 Retinal disorders in diseases classified elsewhere
0.000 0.799 0.201
E71.3 Disorders of fatty-acid metabolism
0.001 0.801 0.198
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.001 0.801 0.198
E71.1 Other disorders of branched-chain amino-acid metabolism
0.001 0.801 0.198
E71.0 Maple-syrup-urine disease
0.001 0.801 0.198
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.001 0.801 0.198
E76.8 Other disorders of glucosaminoglycan metabolism
0.001 0.801 0.198
E76.3 Mucopolysaccharidosis, unspecified
0.001 0.801 0.198
E76.2 Other mucopolysaccharidoses
0.001 0.801 0.198
E76.1 Mucopolysaccharidosis, type II
0.001 0.801 0.198
E76.0 Mucopolysaccharidosis, type I
0.001 0.801 0.198
E77.9 Disorder of glycoprotein metabolism, unspecified
0.001 0.801 0.198
E77.8 Other disorders of glycoprotein metabolism
0.001 0.801 0.198
E77.1 Defects in glycoprotein degradation
0.001 0.801 0.198
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.001 0.801 0.198
I83.1 Varicose veins of lower extremities with inflammation
0.198 0.801 0.000
E84.8 Cystic fibrosis with other manifestations
0.001 0.803 0.196
E84.1 Cystic fibrosis with intestinal manifestations
0.001 0.803 0.196
E84.0 Cystic fibrosis with pulmonary manifestations
0.001 0.803 0.196
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.001 0.804 0.195
E70.8 Other disorders of aromatic amino-acid metabolism
0.001 0.804 0.195
E70.2 Disorders of tyrosine metabolism
0.001 0.804 0.195
E70.1 Other hyperphenylalaninaemias
0.001 0.804 0.195
E70.0 Classical phenylketonuria
0.001 0.804 0.195
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.805 0.195
E84.9 Cystic fibrosis, unspecified
0.001 0.806 0.193
E70.3 Albinism
0.001 0.809 0.191
E50.9 Vitamin A deficiency, unspecified
0.000 0.809 0.191
E50.8 Other manifestations of vitamin A deficiency
0.000 0.809 0.191
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.809 0.191
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.809 0.191
E50.5 Vitamin A deficiency with night blindness
0.000 0.809 0.191
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.809 0.191
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.809 0.191
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.809 0.191
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.809 0.191
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.809 0.191
E63.9 Nutritional deficiency, unspecified
0.000 0.809 0.191
E63.8 Other specified nutritional deficiencies
0.000 0.809 0.191
E63.1 Imbalance of constituents of food intake
0.000 0.809 0.191
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.809 0.191
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.809 0.191
E64.8 Sequelae of other nutritional deficiencies
0.000 0.809 0.191
E64.3 Sequelae of rickets
0.000 0.809 0.191
E64.2 Sequelae of vitamin C deficiency
0.000 0.809 0.191
E64.1 Sequelae of vitamin A deficiency
0.000 0.809 0.191
E64.0 Sequelae of protein-energy malnutrition
0.000 0.809 0.191
E55 Vitamin D deficiency
0.000 0.810 0.190
H20.0 Acute and subacute iridocyclitis
0.190 0.810 0.000
E56.9 Vitamin deficiency, unspecified
0.000 0.814 0.186
E56.8 Deficiency of other vitamins
0.000 0.814 0.186
E56.0 Deficiency of vitamin E
0.000 0.814 0.186
H20.8 Other iridocyclitis
0.185 0.815 0.000
E83 Disorders of mineral metabolism
0.135 0.815 0.049

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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