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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2517544
log Bayes Factor = 195.736
Chromosome 6   position 31,009,508  (GRCh37) Explore rs2517544 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
J45.9 Asthma, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
L40 Psoriasis
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
0.999 0.001 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.999 0.001 0.000
E16 Other disorders of pancreatic internal secretion
0.998 0.002 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.998 0.002 0.000
E16.2 Hypoglycaemia, unspecified
0.997 0.003 0.000
L40.5 Arthropathic psoriasis
0.000 0.003 0.997
J33.9 Nasal polyp, unspecified
0.997 0.003 0.000
J33 Nasal polyp
0.997 0.003 0.000
K90 Intestinal malabsorption
0.996 0.004 0.000
E20-E35 Disorders of other endocrine glands
0.995 0.005 0.000
J45 Asthma
0.995 0.005 0.000
R31 Unspecified haematuria
0.000 0.007 0.993
J33.0 Polyp of nasal cavity
0.991 0.009 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.990 0.010 0.000
D64.9 Anaemia, unspecified
0.990 0.010 0.000
E10.1 With ketoacidosis
0.987 0.013 0.000
D64 Other anaemias
0.986 0.014 0.000
E14.9 Without complications
0.985 0.015 0.000
Chapter X Diseases of the respiratory system
0.984 0.016 0.000
D60-D64 Aplastic and other anaemias
0.984 0.016 0.000
# Top node
0.984 0.016 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.983 0.017 0.000
J40-J47 Chronic lower respiratory diseases
0.982 0.018 0.000
L40.0 Psoriasis vulgaris
0.000 0.018 0.982
E14.3 With ophthalmic complications
0.981 0.019 0.000
J95-J99 Other diseases of the respiratory system
0.976 0.024 0.000
M06 Other rheumatoid arthritis
0.976 0.024 0.000
J98 Other respiratory disorders
0.975 0.025 0.000
K90.9 Intestinal malabsorption, unspecified
0.974 0.026 0.000
M35.0 Sicca syndrome [Sjogren]
0.974 0.026 0.000
M05-M14 Inflammatory polyarthropathies
0.971 0.029 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.970 0.030 0.000
J98.4 Other disorders of lung
0.962 0.038 0.000
J30-J39 Other diseases of upper respiratory tract
0.962 0.038 0.000
E10.2 With renal complications
0.957 0.043 0.000
H30-H36 Disorders of choroid and retina
0.956 0.044 0.000
H36 Retinal disorders in diseases classified elsewhere
0.954 0.046 0.000
E27 Other disorders of adrenal gland
0.954 0.046 0.000
H36.0 Diabetic retinopathy
0.953 0.047 0.000
Chapter VII Diseases of the eye and adnexa
0.952 0.048 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.946 0.054 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.944 0.056 0.000
E27.1 Primary adrenocortical insufficiency
0.943 0.057 0.000
E07 Other disorders of thyroid
0.930 0.070 0.000
M35 Other systemic involvement of connective tissue
0.927 0.073 0.000
K90-K93 Other diseases of the digestive system
0.926 0.074 0.000
E23 Hypofunction and other disorders of pituitary gland
0.924 0.076 0.000
H34 Retinal vascular occlusions
0.923 0.077 0.000
K70-K77 Diseases of liver
0.923 0.077 0.000
Chapter XI Diseases of the digestive system
0.922 0.078 0.000
K75 Other inflammatory liver diseases
0.920 0.080 0.000
E10.4 With neurological complications
0.915 0.085 0.000
K75.4 Autoimmune hepatitis
0.915 0.085 0.000
M20-M25 Other joint disorders
0.914 0.086 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.906 0.094 0.000
E24 Cushing's syndrome
0.900 0.100 0.000
E10.0 With coma
0.900 0.100 0.000
M10 Gout
0.896 0.104 0.000
E23.2 Diabetes insipidus
0.896 0.104 0.000
K73 Chronic hepatitis, not elsewhere classified
0.887 0.113 0.000
E14.6 With other specified complications
0.878 0.122 0.000
L40.8 Other psoriasis
0.000 0.136 0.864
H34.8 Other retinal vascular occlusions
0.860 0.140 0.000
K75.8 Other specified inflammatory liver diseases
0.858 0.142 0.000
D50-D53 Nutritional anaemias
0.857 0.143 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.854 0.146 0.000
E22 Hyperfunction of pituitary gland
0.852 0.148 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.850 0.150 0.000
H34.2 Other retinal artery occlusions
0.847 0.153 0.000
D61 Other aplastic anaemias
0.844 0.156 0.000
J45.0 Predominantly allergic asthma
0.844 0.156 0.000
E07.9 Disorder of thyroid, unspecified
0.842 0.158 0.000
J98.6 Disorders of diaphragm
0.842 0.158 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.841 0.159 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.839 0.161 0.000
H33 Retinal detachments and breaks
0.836 0.164 0.000
E40-E46 Malnutrition
0.833 0.167 0.000
E10.6 With other specified complications
0.832 0.168 0.000
J33.8 Other polyp of sinus
0.829 0.171 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.826 0.174 0.000
E10.8 With unspecified complications
0.826 0.174 0.000
J44 Other chronic obstructive pulmonary disease
0.822 0.178 0.000
E28 Ovarian dysfunction
0.819 0.181 0.000
H33.1 Retinoschisis and retinal cysts
0.819 0.181 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.817 0.183 0.000
D80-D89 Certain disorders involving the immune mechanism
0.816 0.184 0.000
M15-M19 Arthrosis
0.815 0.185 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.811 0.189 0.000
M10.0 Idiopathic gout
0.810 0.190 0.000
M18 Arthrosis of first carpometacarpal joint
0.807 0.193 0.000
J98.2 Interstitial emphysema
0.805 0.195 0.000
J33.1 Polypoid sinus degeneration
0.804 0.196 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.797 0.203 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.795 0.205 0.000
E14.8 With unspecified complications
0.795 0.205 0.000
E14.2 Withrenal complications
0.795 0.205 0.000
J86 Pyothorax
0.793 0.206 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.793 0.207 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.793 0.207 0.000
I73 Other peripheral vascular diseases
0.792 0.208 0.000
J45.1 Nonallergic asthma
0.790 0.210 0.000
M32 Systemic lupus erythematosus
0.789 0.211 0.000
E23.6 Other disorders of pituitary gland
0.785 0.215 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.784 0.216 0.000
E14.1 With ketoacidosis
0.783 0.217 0.000
K72 Hepatic failure, not elsewhere classified
0.783 0.217 0.000
I74 Arterial embolism and thrombosis
0.782 0.218 0.000
M80-M85 Disorders of bone density and structure
0.782 0.218 0.000
E07.8 Other specified disorders of thyroid
0.782 0.218 0.000
M14 Arthropathies in other diseases classified elsewhere
0.781 0.219 0.000
E06 Thyroiditis
0.779 0.221 0.000
K90.8 Other intestinal malabsorption
0.779 0.221 0.000
J85 Abscess of lung and mediastinum
0.778 0.222 0.000
L40.1 Generalised pustular psoriasis
0.000 0.222 0.778
I73.0 Raynaud's syndrome
0.777 0.223 0.000
E31 Polyglandular dysfunction
0.777 0.223 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.776 0.224 0.000
I77 Other disorders of arteries and arterioles
0.776 0.224 0.000
I73.9 Peripheral vascular disease, unspecified
0.776 0.224 0.000
E14.0 With coma
0.774 0.226 0.000
K74 Fibrosis and cirrhosis of liver
0.774 0.226 0.000
E20 Hypoparathyroidism
0.774 0.226 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.768 0.232 0.000
J45.8 Mixed asthma
0.766 0.234 0.000
H31 Other disorders of choroid
0.766 0.234 0.000
I77.6 Arteritis, unspecified
0.764 0.236 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.763 0.237 0.000
M34 Systemic sclerosis
0.760 0.240 0.000
E16.1 Other hypoglycaemia
0.760 0.240 0.000
E24.9 Cushing's syndrome, unspecified
0.756 0.243 0.000
D80 Immunodeficiency with predominantly antibody defects
0.756 0.244 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.756 0.244 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.755 0.245 0.000
J37 Chronic laryngitis and laryngotracheitis
0.752 0.248 0.000
E10.5 With peripheral circulatory complications
0.751 0.249 0.000
J98.8 Other specified respiratory disorders
0.751 0.249 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.750 0.250 0.000
H06.2 Dysthyroid exophthalmos
0.748 0.252 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.747 0.253 0.000
H04 Disorders of lachrymal system
0.744 0.256 0.000
E24.2 Drug-induced Cushing's syndrome
0.741 0.259 0.000
K73.9 Chronic hepatitis, unspecified
0.739 0.261 0.000
M06.4 Inflammatory polyarthropathy
0.739 0.261 0.000
M10.9 Gout, unspecified
0.738 0.262 0.000
L40.3 Pustulosis palmaris et plantaris
0.000 0.262 0.737
I74.8 Embolism and thrombosis of other arteries
0.737 0.263 0.000
M15 Polyarthrosis
0.735 0.265 0.000
M06.8 Other specified rheumatoid arthritis
0.734 0.266 0.000
M40-M43 Deforming dorsopathies
0.730 0.270 0.000
M35.1 Other overlap syndromes
0.728 0.272 0.000
D50 Iron deficiency anaemia
0.725 0.275 0.000
E10.7 With multiple complications
0.724 0.276 0.000
K72.0 Acute and subacute hepatic failure
0.723 0.277 0.000
H33.3 Retinal breaks without detachment
0.722 0.278 0.000
E05.8 Other thyrotoxicosis
0.720 0.280 0.000
J41 Simple and mucopurulent chronic bronchitis
0.719 0.280 0.000
H04.1 Other disorders of lachrymal gland
0.719 0.281 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
E14.7 With multiple complications
0.717 0.283 0.000
E15 Nondiabetic hypoglycaemic coma
0.716 0.284 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.716 0.284 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.716 0.284 0.000
E16.4 Abnormal secretion of gastrin
0.716 0.284 0.000
E16.3 Increased secretion of glucagon
0.716 0.284 0.000
H52 Disorders of refraction and accommodation
0.715 0.285 0.000
D61.9 Aplastic anaemia, unspecified
0.714 0.286 0.000
K90.3 Pancreatic steatorrhoea
0.714 0.286 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.714 0.286 0.000
K90.1 Tropical sprue
0.714 0.286 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.713 0.287 0.000
E32 Diseases of thymus
0.713 0.287 0.000
E30 Disorders of puberty, not elsewhere classified
0.713 0.287 0.000
E25 Adrenogenital disorders
0.713 0.287 0.000
E46 Unspecified protein-energy malnutrition
0.713 0.287 0.000
D50.8 Other iron deficiency anaemias
0.710 0.290 0.000
E14.5 With peripheral circulatory complications
0.709 0.291 0.000
E03.8 Other specified hypothyroidism
0.708 0.291 0.000
E24.0 Pituitary-dependent Cushing's disease
0.708 0.292 0.000
D64.4 Congenital dyserythropoietic anaemia
0.707 0.293 0.000
D64.3 Other sideroblastic anaemias
0.707 0.293 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.707 0.293 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.707 0.293 0.000
D64.0 Hereditary sideroblastic anaemia
0.707 0.293 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.705 0.295 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.705 0.295 0.000
H52.1 Myopia
0.703 0.297 0.000
M33 Dermatopolymyositis
0.701 0.299 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.701 0.299 0.000
J96 Respiratory failure, not elsewhere classified
0.700 0.300 0.000
M06.2 Rheumatoid bursitis
0.700 0.300 0.000
M06.1 Adult-onset Still's disease
0.700 0.300 0.000
M85 Other disorders of bone density and structure
0.700 0.300 0.000
M60-M63 Disorders of muscles
0.699 0.301 0.000
J98.3 Compensatory emphysema
0.699 0.301 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.698 0.302 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.696 0.304 0.000
M08 Juvenile arthritis
0.696 0.304 0.000
K74.3 Primary biliary cirrhosis
0.693 0.306 0.000
M10.96 Gout, unspecified (Lower leg)
0.693 0.307 0.000
J85.2 Abscess of lung without pneumonia
0.692 0.308 0.000
H30 Chorioretinal inflammation
0.691 0.309 0.000
D64.8 Other specified anaemias
0.689 0.311 0.000
E28.3 Primary ovarian failure
0.688 0.312 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.688 0.312 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.686 0.314 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.684 0.316 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.684 0.316 0.000
E27.5 Adrenomedullary hyperfunction
0.684 0.316 0.000
E27.0 Other adrenocortical overactivity
0.684 0.316 0.000
J43 Emphysema
0.681 0.319 0.000
J86.0 Pyothorax with fistula
0.681 0.319 0.000
M10.00 Idiopathic gout (Multiple sites)
0.680 0.320 0.000
M12 Other specific arthropathies
0.678 0.322 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.677 0.322 0.000
D53 Other nutritional anaemias
0.676 0.324 0.000
J30 Vasomotor and allergic rhinitis
0.676 0.324 0.000
M14.2 Diabetic arthropathy
0.669 0.331 0.000
I77.1 Stricture of artery
0.669 0.331 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.669 0.331 0.000
M10.07 Idiopathic gout (Ankle and foot)
0.668 0.332 0.000
M10.94 Gout, unspecified (Hand)
0.668 0.332 0.000
E07.1 Dyshormogenetic goitre
0.667 0.333 0.000
E07.0 Hypersecretion of calcitonin
0.667 0.333 0.000
K71 Toxic liver disease
0.667 0.333 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.665 0.335 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.665 0.335 0.000
M35.5 Multifocal fibrosclerosis
0.665 0.335 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.665 0.335 0.000
M86-M90 Other osteopathies
0.665 0.335 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.664 0.336 0.000
D61.0 Constitutional aplastic anaemia
0.663 0.337 0.000
H50 Other strabismus
0.663 0.337 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.662 0.338 0.000
E23.1 Drug-induced hypopituitarism
0.662 0.338 0.000
Chapter IX Diseases of the circulatory system
0.662 0.338 0.000
H34.0 Transient retinal artery occlusion
0.662 0.338 0.000
K77 Liver disorders in diseases classified elsewhere
0.662 0.338 0.000
H34.1 Central retinal artery occlusion
0.661 0.339 0.000
K75.2 Nonspecific reactive hepatitis
0.660 0.340 0.000
K75.1 Phlebitis of portal vein
0.660 0.340 0.000
I74.5 Embolism and thrombosis of iliac artery
0.658 0.342 0.000
E27.9 Disorder of adrenal gland, unspecified
0.656 0.344 0.000
D62 Acute posthaemorrhagic anaemia
0.656 0.344 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.655 0.345 0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.653 0.347 0.000
D80.1 Nonfamilial hypogammaglobulinaemia
0.652 0.348 0.000
E13 Other specified diabetes mellitus
0.651 0.348 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.651 0.349 0.000
E06.3 Autoimmune thyroiditis
0.651 0.349 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.651 0.349 0.000
E29 Testicular dysfunction
0.649 0.351 0.000
M85.0 Fibrous dysplasia (monostotic)
0.647 0.353 0.000
H33.4 Traction detachment of retina
0.646 0.354 0.000
K75.0 Abscess of liver
0.646 0.354 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.645 0.355 0.000
E24.3 Ectopic ACTH syndrome
0.645 0.355 0.000
E24.1 Nelson's syndrome
0.645 0.355 0.000
M30 Polyarteritis nodosa and related conditions
0.645 0.355 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.644 0.356 0.000
E24.8 Other Cushing's syndrome
0.643 0.356 0.000
M10.4 Other secondary gout
0.642 0.358 0.000
M10.3 Gout due to impairment of renal function
0.642 0.358 0.000
M10.2 Drug-induced gout
0.642 0.358 0.000
M10.1 Lead-induced gout
0.642 0.358 0.000
M83 Adult osteomalacia
0.642 0.358 0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint
0.639 0.361 0.000
J46 Status asthmaticus
0.637 0.362 0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.636 0.364 0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.636 0.364 0.000
D51 Vitamin B12 deficiency anaemia
0.633 0.367 0.000
J86.9 Pyothorax without fistula
0.633 0.367 0.000
E03.1 Congenital hypothyroidism without goitre
0.632 0.367 0.000
M43 Other deforming dorsopathies
0.631 0.369 0.000
E27.2 Addisonian crisis
0.630 0.370 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.630 0.370 0.000
K74.6 Other and unspecified cirrhosis of liver
0.627 0.373 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.626 0.373 0.001
D83 Common variable immunodeficiency
0.625 0.375 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.623 0.377 0.000
M10.04 Idiopathic gout (Hand)
0.621 0.379 0.000
E31.0 Autoimmune polyglandular failure
0.620 0.379 0.000
M35.8 Other specified systemic involvement of connective tissue
0.619 0.381 0.000
M34.1 CR(E)ST syndrome
0.618 0.382 0.000
D55-D59 Haemolytic anaemias
0.616 0.384 0.000
D52 Folate deficiency anaemia
0.616 0.384 0.000
E20.9 Hypoparathyroidism, unspecified
0.616 0.384 0.000
M00-M03 Infectious arthropathies
0.615 0.385 0.000
M14.8 Arthropathies in other specified diseases classified elsewhere
0.612 0.388 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.611 0.389 0.000
E22.8 Other hyperfunction of pituitary gland
0.611 0.389 0.000
M35.7 Hypermobility syndrome
0.610 0.390 0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)
0.610 0.390 0.000
D69 Purpura and other haemorrhagic conditions
0.609 0.391 0.000
D61.8 Other specified aplastic anaemias
0.605 0.394 0.000
D61.3 Idiopathic aplastic anaemia
0.605 0.394 0.000
D61.2 Aplastic anaemia due to other external agents
0.605 0.394 0.000
D61.1 Drug-induced aplastic anaemia
0.603 0.397 0.000
E22.1 Hyperprolactinaemia
0.602 0.398 0.000
J37.0 Chronic laryngitis
0.601 0.398 0.000
M11 Other crystal arthropathies
0.601 0.399 0.000
M35.2 Behcet's disease
0.600 0.400 0.000
M15.2 Bouchard's nodes (with arthropathy)
0.600 0.400 0.000
H31.8 Other specified disorders of choroid
0.599 0.401 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.597 0.403 0.000
E45 Retarded development following protein-energy malnutrition
0.597 0.403 0.000
E43 Unspecified severe protein-energy malnutrition
0.597 0.403 0.000
E42 Marasmic kwashiorkor
0.597 0.403 0.000
E41 Nutritional marasmus
0.597 0.403 0.000
E40 Kwashiorkor
0.597 0.403 0.000
E28.2 Polycystic ovarian syndrome
0.597 0.403 0.000
M32.8 Other forms of systemic lupus erythematosus
0.597 0.403 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.596 0.404 0.000
M10.90 Gout, unspecified (Multiple sites)
0.596 0.404 0.000
M86 Osteomyelitis
0.595 0.405 0.000
H04.4 Chronic inflammation of lachrymal passages
0.594 0.406 0.000
M10.06 Idiopathic gout (Lower leg)
0.594 0.406 0.000
M60 Myositis
0.592 0.408 0.000
H31.9 Disorder of choroid, unspecified
0.592 0.408 0.000
D84 Other immunodeficiencies
0.591 0.409 0.000
M80 Osteoporosis with pathological fracture
0.591 0.409 0.000
M05 Seropositive rheumatoid arthritis
0.591 0.409 0.000
H50.0 Convergent concomitant strabismus
0.588 0.412 0.000
E28.9 Ovarian dysfunction, unspecified
0.587 0.412 0.000
E28.8 Other ovarian dysfunction
0.587 0.412 0.000
E28.1 Androgen excess
0.587 0.412 0.000
E28.0 Oestrogen excess
0.587 0.412 0.000
I71 Aortic aneurysm and dissection
0.586 0.414 0.000
H51 Other disorders of binocular movement
0.586 0.414 0.000
M15.4 Erosive (osteo)arthrosis
0.586 0.414 0.000
J60-J70 Lung diseases due to external agents
0.586 0.414 0.000
M10.09 Idiopathic gout (Site unspecified)
0.585 0.414 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.585 0.415 0.000
H31.1 Choroidal degeneration
0.585 0.415 0.000
D81 Combined immunodeficiencies
0.585 0.415 0.000
I77.2 Rupture of artery
0.585 0.415 0.000
H34.9 Retinal vascular occlusion, unspecified
0.584 0.416 0.000
M15.1 Heberden's nodes (with arthropathy)
0.581 0.419 0.000
M10.08 Idiopathic gout (Other)
0.581 0.419 0.000
M10.05 Idiopathic gout (Pelvic region and thigh)
0.581 0.419 0.000
M10.03 Idiopathic gout (Forearm)
0.581 0.419 0.000
M10.02 Idiopathic gout (Upper arm)
0.581 0.419 0.000
M10.01 Idiopathic gout (Shoulder region)
0.581 0.419 0.000
H43-H45 Disorders of vitreous body and globe
0.581 0.419 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.580 0.420 0.000
E06.5 Other chronic thyroiditis
0.580 0.420 0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint
0.579 0.421 0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral
0.579 0.421 0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral
0.579 0.421 0.000
D60.9 Acquired pure red cell aplasia, unspecified
0.576 0.424 0.000
D69.6 Thrombocytopenia, unspecified
0.576 0.424 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.575 0.424 0.000
H16 Keratitis
0.575 0.425 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.574 0.426 0.000
M34.8 Other forms of systemic sclerosis
0.574 0.426 0.000
M34.0 Progressive systemic sclerosis
0.572 0.428 0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.571 0.429 0.000
H04.3 Acute and unspecified inflammation of lachrymal passages
0.570 0.430 0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.570 0.430 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.569 0.431 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.569 0.431 0.000
M06.3 Rheumatoid nodule
0.569 0.431 0.000
J34 Other disorders of nose and nasal sinuses
0.569 0.431 0.000
M32.9 Systemic lupus erythematosus, unspecified
0.565 0.434 0.000
M32.0 Drug-induced systemic lupus erythematosus
0.565 0.434 0.000
M15.8 Other polyarthrosis
0.565 0.435 0.000
H50.2 Vertical strabismus
0.563 0.437 0.000
M91-M94 Chondropathies
0.563 0.437 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.562 0.438 0.000
D82 Immunodeficiency associated with other major defects
0.561 0.439 0.000
J85.0 Gangrene and necrosis of lung
0.560 0.440 0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.560 0.440 0.000
M14.4 Arthropathy in amyloidosis
0.560 0.440 0.000
M14.3 Lipoid dermatoarthritis
0.560 0.440 0.000
M14.1 Crystal arthropathy in other metabolic disorders
0.560 0.440 0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.560 0.440 0.000
M15.3 Secondary multiple arthrosis
0.560 0.440 0.000
M85.4 Solitary bone cyst
0.559 0.440 0.000
J30.3 Other allergic rhinitis
0.559 0.441 0.000
E06.4 Drug-induced thyroiditis
0.559 0.441 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.559 0.441 0.000
E06.1 Subacute thyroiditis
0.559 0.441 0.000
E06.0 Acute thyroiditis
0.559 0.441 0.000
J85.3 Abscess of mediastinum
0.558 0.442 0.000
I77.0 Arteriovenous fistula, acquired
0.558 0.442 0.000
E31.9 Polyglandular dysfunction, unspecified
0.557 0.443 0.000
E31.8 Other polyglandular dysfunction
0.557 0.443 0.000
E31.1 Polyglandular hyperfunction
0.557 0.443 0.000
I77.5 Necrosis of artery
0.556 0.443 0.000
I77.4 Coeliac artery compression syndrome
0.556 0.443 0.000
I77.3 Arterial fibromuscular dysplasia
0.556 0.443 0.000
K74.4 Secondary biliary cirrhosis
0.555 0.445 0.000
K74.2 Hepatic fibrosis with hepatic sclerosis
0.555 0.445 0.000
K74.1 Hepatic sclerosis
0.555 0.445 0.000
E20.8 Other hypoparathyroidism
0.555 0.445 0.000
E20.1 Pseudohypoparathyroidism
0.555 0.445 0.000
E20.0 Idiopathic hypoparathyroidism
0.555 0.445 0.000
H04.8 Other disorders of lachrymal system
0.555 0.445 0.000
D50.1 Sideropenic dysphagia
0.554 0.446 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.553 0.447 0.000
H50.5 Heterophoria
0.553 0.447 0.000
J43.8 Other emphysema
0.552 0.448 0.000
M33.1 Other dermatomyositis
0.552 0.448 0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.552 0.448 0.000
M85.2 Hyperostosis of skull
0.551 0.449 0.000
H06.3 Other disorders of orbit in diseases classified elsewhere
0.551 0.449 0.000
H06.1 Parasitic infestation of orbit in diseases classified elsewhere
0.551 0.449 0.000
H06.0 Disorders of lachrymal system in diseases classified elsewhere
0.551 0.449 0.000
H31.4 Choroidal detachment
0.549 0.450 0.000
H31.2 Hereditary choroidal dystrophy
0.549 0.450 0.000
H31.3 Choroidal haemorrhage and rupture
0.549 0.451 0.000
H52.4 Presbyopia
0.548 0.452 0.000
K73.8 Other chronic hepatitis, not elsewhere classified
0.548 0.452 0.000
D53.9 Nutritional anaemia, unspecified
0.547 0.453 0.000
M65-M68 Disorders of synovium and tendon
0.547 0.453 0.000
E26 Hyperaldosteronism
0.546 0.454 0.001
M34.2 Systemic sclerosis induced by drugs and chemicals
0.545 0.455 0.000
E14.4 With neurological complications
0.544 0.455 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.544 0.455 0.000
H05 Disorders of orbit
0.544 0.456 0.000
M21 Other acquired deformities of limbs
0.544 0.456 0.000
D80.8 Other immunodeficiencies with predominantly antibody defects
0.542 0.458 0.000
D80.7 Transient hypogammaglobulinaemia of infancy
0.542 0.458 0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.542 0.458 0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.542 0.458 0.000
D80.0 Hereditary hypogammaglobulinaemia
0.542 0.458 0.000
H04.9 Disorder of lachrymal system, unspecified
0.542 0.458 0.000
J85.1 Abscess of lung with pneumonia
0.542 0.458 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.541 0.459 0.000
J30.0 Vasomotor rhinitis
0.540 0.460 0.000
M40 Kyphosis and lordosis
0.540 0.460 0.000
M34.9 Systemic sclerosis, unspecified
0.540 0.460 0.000
J37.1 Chronic laryngotracheitis
0.539 0.461 0.000
M85.9 Disorder of bone density and structure, unspecified
0.538 0.462 0.000
M81 Osteoporosis without pathological fracture
0.538 0.462 0.000
K72.1 Chronic hepatic failure
0.537 0.463 0.000
D60.8 Other acquired pure red cell aplasias
0.535 0.465 0.000
D60.1 Transient acquired pure red cell aplasia
0.535 0.465 0.000
D60.0 Chronic acquired pure red cell aplasia
0.535 0.465 0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.535 0.465 0.000
H04.0 Dacryoadenitis
0.533 0.467 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.533 0.467 0.000
J41.0 Simple chronic bronchitis
0.531 0.469 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.530 0.470 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.530 0.470 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.530 0.470 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.530 0.470 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.530 0.470 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.530 0.470 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.530 0.470 0.000
J43.2 Centrilobular emphysema
0.530 0.470 0.000
M88 Paget's disease of bone [osteitis deformans]
0.529 0.471 0.000
M10.98 Gout, unspecified (Other)
0.529 0.471 0.000
M10.95 Gout, unspecified (Pelvic region and thigh)
0.529 0.471 0.000
M10.91 Gout, unspecified (Shoulder region)
0.529 0.471 0.000
M83.1 Senile osteomalacia
0.529 0.471 0.000
M15.0 Primary generalised (osteo)arthrosis
0.527 0.473 0.000
M06.88 Other specified rheumatoid arthritis (Other)
0.526 0.474 0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.526 0.474 0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.526 0.474 0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.526 0.474 0.000
M06.84 Other specified rheumatoid arthritis (Hand)
0.526 0.474 0.000
M06.83 Other specified rheumatoid arthritis (Forearm)
0.526 0.474 0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.526 0.474 0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.526 0.474 0.000
M12.5 Traumatic arthropathy
0.524 0.476 0.000
M22 Disorders of patella
0.524 0.476 0.000
E23.7 Disorder of pituitary gland, unspecified
0.523 0.477 0.000
M42 Spinal osteochondrosis
0.523 0.477 0.000
M82 Osteoporosis in diseases classified elsewhere
0.520 0.480 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.519 0.480 0.000
J41.8 Mixed simple and mucopurulent chronic bronchitis
0.516 0.484 0.000
J41.1 Mucopurulent chronic bronchitis
0.516 0.484 0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.516 0.484 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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