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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3117113
log Bayes Factor = 216.453
Chromosome 6   position 32,325,292  (GRCh37) Explore rs3117113 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
E14.9 Without complications
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
J33 Nasal polyp
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E10.4 With neurological complications
0.000 0.000 1.000
J33.0 Polyp of nasal cavity
0.000 0.000 1.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.000 1.000
M35.3 Polymyalgia rheumatica
0.000 0.000 1.000
J33.9 Nasal polyp, unspecified
0.000 0.001 0.999
E70-E90 Metabolic disorders
0.000 0.001 0.999
E05.9 Thyrotoxicosis, unspecified
0.000 0.001 0.999
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.001 0.999
L40-L45 Papulosquamous disorders
0.000 0.001 0.999
H36 Retinal disorders in diseases classified elsewhere
0.000 0.001 0.999
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.001 0.999
E11.3 With ophthalmic complications
0.000 0.002 0.998
M07 Psoriatic and enteropathic arthropathies
0.000 0.002 0.998
L40.9 Psoriasis, unspecified
0.000 0.002 0.998
H30-H36 Disorders of choroid and retina
0.000 0.002 0.998
M07.3 Other psoriatic arthropathies
0.000 0.003 0.997
E14.3 With ophthalmic complications
0.000 0.003 0.997
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.004 0.996
G35-G37 Demyelinating diseases of the central nervous system
0.995 0.005 0.000
J33.8 Other polyp of sinus
0.000 0.005 0.995
G37 Other demyelinating diseases of central nervous system
0.994 0.006 0.000
M35 Other systemic involvement of connective tissue
0.000 0.006 0.994
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.007 0.993
G37.9 Demyelinating disease of central nervous system, unspecified
0.993 0.007 0.000
E10.5 With peripheral circulatory complications
0.000 0.007 0.993
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.008 0.992
E11.1 With ketoacidosis
0.000 0.009 0.991
I10 Essential (primary) hypertension
0.000 0.010 0.990
# Top node
0.000 0.010 0.990
I10-I15 Hypertensive diseases
0.000 0.011 0.989
Chapter VII Diseases of the eye and adnexa
0.000 0.012 0.988
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.014 0.986
M20-M25 Other joint disorders
0.000 0.014 0.986
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.016 0.984
L43 Lichen planus
0.000 0.017 0.983
Chapter IX Diseases of the circulatory system
0.000 0.024 0.976
E10.2 With renal complications
0.000 0.025 0.975
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.030 0.970
E06 Thyroiditis
0.000 0.033 0.967
L43.9 Lichen planus, unspecified
0.000 0.040 0.960
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.041 0.959
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.044 0.956
E10.8 With unspecified complications
0.000 0.046 0.954
I22 Subsequent myocardial infarction
0.000 0.048 0.952
M65-M68 Disorders of synovium and tendon
0.000 0.049 0.951
H40-H42 Glaucoma
0.000 0.049 0.951
I20-I25 Ischaemic heart diseases
0.000 0.050 0.950
I12 Hypertensive renal disease
0.000 0.052 0.948
E06.3 Autoimmune thyroiditis
0.000 0.053 0.947
M06.0 Seronegative rheumatoid arthritis
0.000 0.054 0.946
E10.0 With coma
0.000 0.058 0.942
H34 Retinal vascular occlusions
0.000 0.059 0.941
M06.3 Rheumatoid nodule
0.000 0.061 0.939
M34 Systemic sclerosis
0.000 0.061 0.939
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.061 0.939
M65 Synovitis and tenosynovitis
0.000 0.062 0.938
M45-M49 Spondylopathies
0.000 0.065 0.935
M45 Ankylosing spondylitis
0.000 0.066 0.934
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.067 0.933
I12.9 Hypertensive renal disease without renal failure
0.000 0.069 0.931
H35 Other retinal disorders
0.000 0.073 0.927
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.076 0.924
H40 Glaucoma
0.000 0.076 0.924
H40.9 Glaucoma, unspecified
0.000 0.078 0.922
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.079 0.921
M65.9 Synovitis and tenosynovitis, unspecified
0.000 0.086 0.914
E78.2 Mixed hyperlipidaemia
0.000 0.091 0.909
M06.4 Inflammatory polyarthropathy
0.000 0.093 0.907
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.100 0.900
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.102 0.898
E88 Other metabolic disorders
0.000 0.106 0.894
E07 Other disorders of thyroid
0.000 0.107 0.893
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.107 0.893
E78.1 Pure hyperglyceridaemia
0.000 0.107 0.893
H35.4 Peripheral retinal degeneration
0.000 0.108 0.892
E11.2 With renal complications
0.000 0.113 0.887
H35.8 Other specified retinal disorders
0.000 0.125 0.875
E11.5 With peripheral circulatory complications
0.000 0.128 0.872
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.137 0.863
G37.8 Other specified demyelinating diseases of central nervous system
0.859 0.140 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.142 0.858
L40.8 Other psoriasis
0.000 0.145 0.855
L43.8 Other lichen planus
0.000 0.146 0.854
M35.7 Hypermobility syndrome
0.000 0.146 0.854
M35.1 Other overlap syndromes
0.000 0.147 0.853
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.148 0.852
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.149 0.851
M34.1 CR(E)ST syndrome
0.000 0.150 0.850
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.158 0.842
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.000 0.162 0.838
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.165 0.835
M34.9 Systemic sclerosis, unspecified
0.000 0.167 0.833
M06.34 Rheumatoid nodule (Hand)
0.000 0.168 0.832
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.171 0.829
H34.8 Other retinal vascular occlusions
0.000 0.171 0.829
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.173 0.827
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.174 0.826
E10.6 With other specified complications
0.000 0.183 0.817
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.190 0.810
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.191 0.809
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.192 0.808
H35.6 Retinal haemorrhage
0.000 0.193 0.807
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.193 0.807
H34.2 Other retinal artery occlusions
0.000 0.196 0.804
E07.9 Disorder of thyroid, unspecified
0.000 0.196 0.804
H33 Retinal detachments and breaks
0.000 0.198 0.802
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)
0.000 0.201 0.799
H43-H45 Disorders of vitreous body and globe
0.000 0.201 0.799
E11.8 With unspecified complications
0.000 0.202 0.798
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.000 0.204 0.796
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.204 0.796
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.000 0.206 0.794
I15 Secondary hypertension
0.000 0.209 0.791
E14.4 With neurological complications
0.000 0.209 0.791
M31 Other necrotising vasculopathies
0.000 0.211 0.789
E03.8 Other specified hypothyroidism
0.000 0.211 0.789
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.218 0.782
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.218 0.782
M30 Polyarteritis nodosa and related conditions
0.000 0.224 0.776
E74 Other disorders of carbohydrate metabolism
0.000 0.226 0.774
M35.2 Behcet's disease
0.000 0.239 0.761
I22.8 Subsequent myocardial infarction of other sites
0.000 0.243 0.757
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.244 0.756
E83 Disorders of mineral metabolism
0.306 0.246 0.448
E14.5 With peripheral circulatory complications
0.000 0.247 0.753
H33.3 Retinal breaks without detachment
0.000 0.247 0.753
H35.7 Separation of retinal layers
0.000 0.250 0.750
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.255 0.745
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.255 0.745
H40.4 Glaucoma secondary to eye inflammation
0.000 0.257 0.743
E89.0 Postprocedural hypothyroidism
0.000 0.259 0.741
H43 Disorders of vitreous body
0.000 0.260 0.740
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.000 0.260 0.740
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.264 0.736
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.733 0.267 0.000
L40.3 Pustulosis palmaris et plantaris
0.000 0.268 0.732
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.268 0.732
M65.1 Other infective (teno)synovitis
0.000 0.268 0.732
E14.2 Withrenal complications
0.000 0.269 0.731
G36 Other acute disseminated demyelination
0.728 0.272 0.000
E40-E46 Malnutrition
0.000 0.277 0.723
M14 Arthropathies in other diseases classified elsewhere
0.000 0.277 0.723
Chapter VIII Diseases of the ear and mastoid process
0.000 0.280 0.720
H30 Chorioretinal inflammation
0.000 0.280 0.720
H34.9 Retinal vascular occlusion, unspecified
0.000 0.282 0.718
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E14.8 With unspecified complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.6 With other specified complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.2 Rheumatoid vasculitis
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
J33.1 Polypoid sinus degeneration
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E78.6 Lipoprotein deficiency
0.000 0.283 0.717
E78.3 Hyperchylomicronaemia
0.000 0.283 0.717
E77 Disorders of glycoprotein metabolism
0.000 0.284 0.716
E76 Disorders of glycosaminoglycan metabolism
0.000 0.284 0.716
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.284 0.716
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.284 0.716
L44 Other papulosquamous disorders
0.000 0.284 0.716
L41 Parapsoriasis
0.000 0.284 0.716
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.284 0.716
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.284 0.716
H34.1 Central retinal artery occlusion
0.000 0.284 0.716
M07.5 Arthropathy in ulcerative colitis
0.000 0.284 0.715
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.284 0.715
M07.2 Psoriatic spondylitis
0.000 0.284 0.715
M07.1 Arthritis mutilans
0.000 0.284 0.715
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.284 0.715
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.285 0.715
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.285 0.715
M07.38 Other psoriatic arthropathies (Other)
0.000 0.285 0.715
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.285 0.715
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.285 0.715
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.285 0.715
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.285 0.715
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.285 0.715
G37.5 Concentric sclerosis [Balo]
0.713 0.287 0.000
G37.4 Subacute necrotising myelitis
0.713 0.287 0.000
G37.2 Central pontine myelinolysis
0.713 0.287 0.000
G37.1 Central demyelination of corpus callosum
0.713 0.287 0.000
G37.0 Diffuse sclerosis
0.713 0.287 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.287 0.713
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.287 0.713
M35.5 Multifocal fibrosclerosis
0.000 0.287 0.713
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.287 0.713
E88.2 Lipomatosis, not elsewhere classified
0.000 0.288 0.712
E88.8 Other specified metabolic disorders
0.000 0.288 0.712
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.290 0.710
I00-I02 Acute rheumatic fever
0.000 0.291 0.709
L40.0 Psoriasis vulgaris
0.000 0.291 0.709
I13 Hypertensive heart and renal disease
0.000 0.291 0.709
I11 Hypertensive heart disease
0.000 0.292 0.708
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.293 0.707
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.293 0.707
L43.3 Subacute (active) lichen planus
0.000 0.295 0.705
L43.2 Lichenoid drug reaction
0.000 0.295 0.705
L43.1 Bullous lichen planus
0.000 0.295 0.705
L43.0 Hypertrophic lichen planus
0.000 0.295 0.705
H40.5 Glaucoma secondary to other eye disorders
0.000 0.295 0.705
E70 Disorders of aromatic amino-acid metabolism
0.000 0.299 0.701
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)
0.000 0.303 0.697
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.304 0.696
E11.6 With other specified complications
0.000 0.304 0.696
E06.5 Other chronic thyroiditis
0.000 0.306 0.693
E06.4 Drug-induced thyroiditis
0.000 0.306 0.693
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.306 0.693
E06.1 Subacute thyroiditis
0.000 0.306 0.693
E06.0 Acute thyroiditis
0.000 0.306 0.693
H60-H62 Diseases of external ear
0.000 0.307 0.693
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.307 0.692
E79 Disorders of purine and pyrimidine metabolism
0.000 0.308 0.692
L57.0 Actinic keratosis
0.000 0.309 0.691
M34.8 Other forms of systemic sclerosis
0.000 0.311 0.688
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.315 0.685
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.318 0.682
E16.1 Other hypoglycaemia
0.000 0.318 0.681
H42 Glaucoma in diseases classified elsewhere
0.000 0.318 0.681
H35.2 Other proliferative retinopathy
0.000 0.320 0.680
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.322 0.678
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.322 0.678
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.322 0.678
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.322 0.678
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.322 0.678
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.322 0.678
M49 Spondylopathies in diseases classified elsewhere
0.000 0.322 0.678
E13 Other specified diabetes mellitus
0.000 0.323 0.677
E78.4 Other hyperlipidaemia
0.000 0.323 0.677
E07.8 Other specified disorders of thyroid
0.000 0.323 0.677
M12 Other specific arthropathies
0.000 0.324 0.676
H34.0 Transient retinal artery occlusion
0.000 0.325 0.675
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.327 0.673
M06.38 Rheumatoid nodule (Other)
0.000 0.327 0.673
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.327 0.673
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.327 0.673
M06.33 Rheumatoid nodule (Forearm)
0.000 0.327 0.673
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.327 0.673
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.327 0.673
M34.2 Systemic sclerosis induced by drugs and chemicals
0.000 0.327 0.673
M34.0 Progressive systemic sclerosis
0.000 0.327 0.673
M65.2 Calcific tendinitis
0.000 0.327 0.672
M65.0 Abscess of tendon sheath
0.000 0.327 0.672
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.330 0.670
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.330 0.670
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.330 0.670
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.330 0.670
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.330 0.670
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.330 0.670
M07.6 Other enteropathic arthropathies
0.000 0.332 0.668
E84 Cystic fibrosis
0.000 0.334 0.666
H35.1 Retinopathy of prematurity
0.000 0.335 0.665
E20-E35 Disorders of other endocrine glands
0.000 0.336 0.664
H40.6 Glaucoma secondary to drugs
0.000 0.338 0.662
H40.3 Glaucoma secondary to eye trauma
0.000 0.338 0.662
E72 Other disorders of amino-acid metabolism
0.000 0.340 0.659
H43.3 Other vitreous opacities
0.000 0.343 0.657
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.344 0.656
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.345 0.655
M65.98 Synovitis and tenosynovitis, unspecified (Other)
0.000 0.345 0.655
M31.6 Other giant cell arteritis
0.000 0.345 0.655
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)
0.000 0.348 0.652
H61 Other disorders of external ear
0.000 0.349 0.651
L10-L14 Bullous disorders
0.000 0.350 0.650
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.350 0.650
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.350 0.650
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.350 0.650
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.350 0.650
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.350 0.650
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.350 0.650
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.350 0.650
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.350 0.650
M91-M94 Chondropathies
0.000 0.350 0.650
M31.3 Wegener's granulomatosis
0.000 0.352 0.648
E06.9 Thyroiditis, unspecified
0.000 0.354 0.646
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec
0.000 0.354 0.646
M65.48 Radial styloid tenosynovitis [de Quervain]-Other
0.000 0.354 0.646
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot
0.000 0.354 0.646
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg
0.000 0.354 0.646
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh
0.000 0.354 0.646
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm
0.000 0.354 0.646
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region
0.000 0.354 0.646
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)
0.000 0.354 0.646
M66 Spontaneous rupture of synovium and tendon
0.000 0.355 0.645
E88.3 Tumour lysis syndrome
0.000 0.356 0.644
H33.4 Traction detachment of retina
0.000 0.357 0.643
M32 Systemic lupus erythematosus
0.000 0.357 0.642
M86-M90 Other osteopathies
0.000 0.359 0.641
E88.9 Metabolic disorder, unspecified
0.000 0.359 0.641
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.359 0.641
E07.1 Dyshormogenetic goitre
0.000 0.359 0.640
E07.0 Hypersecretion of calcitonin
0.000 0.359 0.640
H40.1 Primary open-angle glaucoma
0.000 0.360 0.640
E11.4 With neurological complications
0.000 0.361 0.639
D64.9 Anaemia, unspecified
0.000 0.366 0.634
H43.9 Disorder of vitreous body, unspecified
0.000 0.369 0.631
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.374 0.626
D64 Other anaemias
0.000 0.376 0.624
M11 Other crystal arthropathies
0.000 0.377 0.623
D60-D64 Aplastic and other anaemias
0.000 0.378 0.622
I15.9 Seconday hypertension, unspecified
0.000 0.380 0.620
L42 Pityriasis rosea
0.000 0.383 0.616
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.387 0.612
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.388 0.612
M10 Gout
0.000 0.389 0.611
E05.8 Other thyrotoxicosis
0.000 0.391 0.609
I15.1 Hypertension secondary to other renal disorders
0.000 0.393 0.607
E89.4 Postprocedural ovarian failure
0.000 0.394 0.606
E73 Lactose intolerance
0.000 0.394 0.606
H60 Otitis externa
0.000 0.398 0.602
H61.0 Perichondritis of external ear
0.000 0.399 0.601
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.000 0.401 0.599
L20-L30 Dermatitis and eczema
0.000 0.402 0.598
E23 Hypofunction and other disorders of pituitary gland
0.000 0.405 0.595
M35.0 Sicca syndrome [Sjogren]
0.000 0.408 0.592
M33 Dermatopolymyositis
0.000 0.409 0.591
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.409 0.591
I23 Certain current complications following acute myocardial infarction
0.000 0.409 0.591
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.409 0.590
M30.0 Polyarteritis nodosa
0.000 0.410 0.590
E28 Ovarian dysfunction
0.000 0.414 0.586
M60-M63 Disorders of muscles
0.000 0.414 0.586
M86 Osteomyelitis
0.000 0.414 0.586
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.415 0.585
M65.14 Other infective (teno)synovitis (Hand)
0.000 0.416 0.584
H33.1 Retinoschisis and retinal cysts
0.000 0.417 0.583
M14.6 Neuropathic arthropathy
0.000 0.417 0.583
L55 Sunburn
0.000 0.420 0.580
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.420 0.579
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.420 0.579
E89.5 Postprocedural testicular hypofunction
0.000 0.420 0.579
E89.1 Postprocedural hypoinsulinaemia
0.000 0.420 0.579
L28 Lichen simplex chronicus and prurigo
0.000 0.422 0.578
H61.8 Other specified disorders of external ear
0.000 0.422 0.578
M31.9 Necrotising vasculopathy, unspecified
0.000 0.424 0.576
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.427 0.573
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.000 0.430 0.570
E11.0 With coma
0.000 0.432 0.568
I15.8 Other secondary hypertension
0.000 0.432 0.567
I15.2 Hypertension secondary to endocrine disorders
0.000 0.432 0.567
I15.0 Renovascular hypertension
0.000 0.434 0.566
M31.8 Other specified necrotising vasculopathies
0.000 0.434 0.566
M31.7 Microscopic polyangiitis
0.000 0.434 0.566
M31.4 Aortic arch syndrome [Takayasu]
0.000 0.434 0.566
M31.2 Lethal midline granuloma
0.000 0.434 0.566
M31.1 Thrombotic microangiopathy
0.000 0.434 0.566
E65-E68 Obesity and other hyperalimentation
0.000 0.437 0.563
E89.3 Postprocedural hypopituitarism
0.000 0.437 0.563
E78.8 Other disorders of lipoprotein metabolism
0.000 0.438 0.562
E03.1 Congenital hypothyroidism without goitre
0.000 0.438 0.561
M00-M03 Infectious arthropathies
0.000 0.440 0.560
H43.2 Crystalline deposits in vitreous body
0.000 0.441 0.559
M86.9 Osteomyelitis, unspecified
0.000 0.443 0.557
M30.8 Other conditions related to polyarteritis nodosa
0.000 0.443 0.557
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]
0.000 0.443 0.557
M30.2 Juvenile polyarteritis
0.000 0.443 0.557
H61.1 Non-infective disorders of pinna
0.000 0.444 0.556
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.445 0.555
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.445 0.555
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.445 0.555
E74.2 Disorders of galactose metabolism
0.000 0.445 0.555
E74.1 Disorders of fructose metabolism
0.000 0.445 0.555
E74.0 Glycogen storage disease
0.000 0.445 0.555
L28.0 Lichen simplex chronicus
0.000 0.447 0.553
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.455 0.545
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.000 0.457 0.543
E27 Other disorders of adrenal gland
0.000 0.457 0.543
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.458 0.542
E83.8 Other disorders of mineral metabolism
0.220 0.459 0.321
E83.2 Disorders of zinc metabolism
0.220 0.459 0.321
E83.0 Disorders of copper metabolism
0.220 0.459 0.321
M80-M85 Disorders of bone density and structure
0.000 0.461 0.539
H35.5 Hereditary retinal dystrophy
0.000 0.463 0.537
G36.0 Neuromyelitis optica [Devic]
0.537 0.463 0.000
M15-M19 Arthrosis
0.000 0.465 0.535
H33.0 Retinal detachment with retinal break
0.000 0.467 0.533
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.468 0.532
H43.0 Vitreous prolapse
0.000 0.469 0.531
H60.3 Other infective otitis externa
0.000 0.469 0.531
I21 Acute myocardial infarction
0.000 0.470 0.530
L58 Radiodermatitis
0.000 0.470 0.530
I24 Other acute ischaemic heart diseases
0.000 0.471 0.529
H40.0 Glaucoma suspect
0.000 0.472 0.528
L57.5 Actinic granuloma
0.000 0.475 0.525
L57.3 Poikiloderma of Civatte
0.000 0.475 0.525
L57.2 Cutis rhomboidalis nuchae
0.000 0.475 0.525
L57.1 Actinic reticuloid
0.000 0.475 0.525
M65.19 Other infective (teno)synovitis (Site unspecified)
0.000 0.475 0.525
M65.18 Other infective (teno)synovitis (Other)
0.000 0.475 0.525
M65.17 Other infective (teno)synovitis (Ankle and foot)
0.000 0.475 0.525
M65.16 Other infective (teno)synovitis (Lower leg)
0.000 0.475 0.525
M65.15 Other infective (teno)synovitis (Pelvic region and thigh)
0.000 0.475 0.525
M65.13 Other infective (teno)synovitis (Forearm)
0.000 0.475 0.525
M65.12 Other infective (teno)synovitis (Upper arm)
0.000 0.475 0.525
M65.11 Other infective (teno)synovitis (Shoulder region)
0.000 0.475 0.525
M65.10 Other infective (teno)synovitis (Multiple sites)
0.000 0.475 0.525
E46 Unspecified protein-energy malnutrition
0.000 0.475 0.525
H43.1 Vitreous haemorrhage
0.000 0.476 0.524
E83.9 Disorder of mineral metabolism, unspecified
0.238 0.478 0.284
G36.9 Acute disseminated demyelination, unspecified
0.522 0.478 0.000
G36.8 Other specified acute disseminated demyelination
0.522 0.478 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.522 0.478 0.000
E89.2 Postprocedural hypoparathyroidism
0.000 0.479 0.521
H30.9 Chorioretinal inflammation, unspecified
0.000 0.480 0.520
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.481 0.518
E45 Retarded development following protein-energy malnutrition
0.000 0.481 0.518
E43 Unspecified severe protein-energy malnutrition
0.000 0.481 0.518
E42 Marasmic kwashiorkor
0.000 0.481 0.518
E41 Nutritional marasmus
0.000 0.481 0.518
E40 Kwashiorkor
0.000 0.481 0.518
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.481 0.518
M14.4 Arthropathy in amyloidosis
0.000 0.481 0.518
M14.3 Lipoid dermatoarthritis
0.000 0.481 0.518
M14.2 Diabetic arthropathy
0.000 0.481 0.518
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.481 0.518
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.481 0.518
I00 Rheumatic fever without mention of heart involvement
0.000 0.482 0.518
I70 Atherosclerosis
0.000 0.483 0.517
E28.3 Primary ovarian failure
0.000 0.484 0.516
H30.8 Other chorioretinal inflammations
0.000 0.484 0.516
H30.2 Posterior cyclitis
0.000 0.484 0.516
H30.1 Disseminated chorioretinal inflammation
0.000 0.484 0.516
H30.0 Focal chorioretinal inflammation
0.000 0.484 0.516
H43.8 Other disorders of vitreous body
0.000 0.485 0.515
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.486 0.514
M06.18 Adult-onset Still's disease (Other)
0.000 0.486 0.514
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.486 0.514
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.486 0.514
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.486 0.514
M06.14 Adult-onset Still's disease (Hand)
0.000 0.486 0.514
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.486 0.514
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.486 0.514
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.486 0.514
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.486 0.514

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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