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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3129931
log Bayes Factor = 217.166
Chromosome 6   position 32,335,516  (GRCh37) Explore rs3129931 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
E14.9 Without complications
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
E10.4 With neurological complications
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.000 1.000
M35.3 Polymyalgia rheumatica
0.000 0.001 0.999
J33 Nasal polyp
0.000 0.001 0.999
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.001 0.999
J33.0 Polyp of nasal cavity
0.000 0.001 0.999
E70-E90 Metabolic disorders
0.000 0.001 0.999
J33.9 Nasal polyp, unspecified
0.000 0.001 0.999
L40-L45 Papulosquamous disorders
0.000 0.001 0.999
E05.9 Thyrotoxicosis, unspecified
0.000 0.001 0.999
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.001 0.999
E11.3 With ophthalmic complications
0.000 0.002 0.998
M07 Psoriatic and enteropathic arthropathies
0.000 0.002 0.998
H36 Retinal disorders in diseases classified elsewhere
0.000 0.002 0.998
M07.3 Other psoriatic arthropathies
0.000 0.002 0.998
H30-H36 Disorders of choroid and retina
0.000 0.003 0.997
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.003 0.997
E14.3 With ophthalmic complications
0.000 0.003 0.997
G35-G37 Demyelinating diseases of the central nervous system
0.996 0.004 0.000
L40.9 Psoriasis, unspecified
0.000 0.004 0.996
G37 Other demyelinating diseases of central nervous system
0.995 0.005 0.000
M35 Other systemic involvement of connective tissue
0.000 0.006 0.994
G37.9 Demyelinating disease of central nervous system, unspecified
0.994 0.006 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.007 0.993
I10 Essential (primary) hypertension
0.000 0.007 0.993
E10.5 With peripheral circulatory complications
0.000 0.007 0.993
I10-I15 Hypertensive diseases
0.000 0.008 0.992
J33.8 Other polyp of sinus
0.000 0.008 0.992
# Top node
0.000 0.008 0.992
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.008 0.992
E11.1 With ketoacidosis
0.000 0.009 0.991
Chapter VII Diseases of the eye and adnexa
0.000 0.010 0.990
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.012 0.988
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.013 0.987
M20-M25 Other joint disorders
0.000 0.013 0.987
L43 Lichen planus
0.000 0.019 0.981
Chapter IX Diseases of the circulatory system
0.000 0.020 0.980
E10.2 With renal complications
0.000 0.024 0.976
E06 Thyroiditis
0.000 0.026 0.974
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.029 0.971
I12 Hypertensive renal disease
0.000 0.034 0.966
H34 Retinal vascular occlusions
0.000 0.037 0.963
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.038 0.962
H40-H42 Glaucoma
0.000 0.041 0.959
E06.3 Autoimmune thyroiditis
0.000 0.043 0.957
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.044 0.956
E10.8 With unspecified complications
0.000 0.045 0.955
I22 Subsequent myocardial infarction
0.000 0.046 0.954
L43.9 Lichen planus, unspecified
0.000 0.046 0.954
I12.9 Hypertensive renal disease without renal failure
0.000 0.048 0.952
I20-I25 Ischaemic heart diseases
0.000 0.048 0.952
M06.0 Seronegative rheumatoid arthritis
0.000 0.049 0.951
M34 Systemic sclerosis
0.000 0.052 0.948
E10.0 With coma
0.000 0.058 0.942
M06.3 Rheumatoid nodule
0.000 0.059 0.941
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.060 0.940
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.060 0.940
M65-M68 Disorders of synovium and tendon
0.000 0.062 0.938
H40 Glaucoma
0.000 0.062 0.938
H40.9 Glaucoma, unspecified
0.000 0.065 0.935
M45-M49 Spondylopathies
0.000 0.072 0.928
M45 Ankylosing spondylitis
0.000 0.073 0.927
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.077 0.923
M65 Synovitis and tenosynovitis
0.000 0.080 0.920
E78.2 Mixed hyperlipidaemia
0.000 0.087 0.913
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.087 0.913
M06.4 Inflammatory polyarthropathy
0.000 0.091 0.909
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.100 0.900
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.101 0.899
M65.9 Synovitis and tenosynovitis, unspecified
0.000 0.102 0.898
E07 Other disorders of thyroid
0.000 0.111 0.889
E88 Other metabolic disorders
0.000 0.111 0.889
E11.5 With peripheral circulatory complications
0.000 0.112 0.888
H34.8 Other retinal vascular occlusions
0.000 0.112 0.888
E78.1 Pure hyperglyceridaemia
0.000 0.113 0.887
H35 Other retinal disorders
0.000 0.120 0.880
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.127 0.873
E11.2 With renal complications
0.000 0.131 0.869
M34.1 CR(E)ST syndrome
0.000 0.134 0.866
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.135 0.865
G37.8 Other specified demyelinating diseases of central nervous system
0.859 0.141 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.141 0.859
M35.7 Hypermobility syndrome
0.000 0.143 0.857
L40.8 Other psoriasis
0.000 0.144 0.856
M35.1 Other overlap syndromes
0.000 0.145 0.855
L43.8 Other lichen planus
0.000 0.146 0.854
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.147 0.853
M34.9 Systemic sclerosis, unspecified
0.000 0.149 0.851
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.151 0.849
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.154 0.846
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.162 0.838
M06.34 Rheumatoid nodule (Hand)
0.000 0.164 0.836
H34.2 Other retinal artery occlusions
0.000 0.164 0.836
H35.4 Peripheral retinal degeneration
0.000 0.165 0.835
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.174 0.826
D64.9 Anaemia, unspecified
0.000 0.174 0.826
H35.8 Other specified retinal disorders
0.000 0.177 0.823
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.177 0.823
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.180 0.820
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.000 0.185 0.815
D64 Other anaemias
0.000 0.186 0.814
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.188 0.812
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.189 0.811
D60-D64 Aplastic and other anaemias
0.000 0.190 0.810
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.190 0.810
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.190 0.810
I15 Secondary hypertension
0.000 0.192 0.808
E74 Other disorders of carbohydrate metabolism
0.000 0.193 0.807
E10.6 With other specified complications
0.000 0.193 0.807
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.196 0.804
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.201 0.799
E03.8 Other specified hypothyroidism
0.000 0.208 0.792
E14.4 With neurological complications
0.000 0.208 0.792
E07.9 Disorder of thyroid, unspecified
0.000 0.209 0.791
E11.8 With unspecified complications
0.000 0.211 0.789
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.000 0.213 0.787
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.000 0.214 0.786
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)
0.000 0.214 0.786
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.215 0.785
M30 Polyarteritis nodosa and related conditions
0.000 0.220 0.780
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.236 0.764
M35.2 Behcet's disease
0.000 0.237 0.763
I22.8 Subsequent myocardial infarction of other sites
0.000 0.238 0.762
H35.6 Retinal haemorrhage
0.000 0.240 0.760
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.240 0.760
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.240 0.760
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.241 0.758
E89.0 Postprocedural hypothyroidism
0.000 0.243 0.757
E83 Disorders of mineral metabolism
0.306 0.244 0.449
H40.4 Glaucoma secondary to eye inflammation
0.000 0.245 0.755
E14.5 With peripheral circulatory complications
0.000 0.246 0.754
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.259 0.741
H34.9 Retinal vascular occlusion, unspecified
0.000 0.264 0.736
H34.1 Central retinal artery occlusion
0.000 0.266 0.734
L40.3 Pustulosis palmaris et plantaris
0.000 0.267 0.733
E14.2 Withrenal complications
0.000 0.268 0.732
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.268 0.732
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.000 0.271 0.729
G36 Other acute disseminated demyelination
0.728 0.272 0.000
L57.0 Actinic keratosis
0.000 0.273 0.727
H30 Chorioretinal inflammation
0.000 0.280 0.720
E40-E46 Malnutrition
0.000 0.282 0.718
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E14.8 With unspecified complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.6 With other specified complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.2 Rheumatoid vasculitis
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E78.6 Lipoprotein deficiency
0.000 0.283 0.717
E78.3 Hyperchylomicronaemia
0.000 0.283 0.717
J33.1 Polypoid sinus degeneration
0.000 0.283 0.716
E77 Disorders of glycoprotein metabolism
0.000 0.284 0.716
E76 Disorders of glycosaminoglycan metabolism
0.000 0.284 0.716
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.284 0.716
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.284 0.716
L44 Other papulosquamous disorders
0.000 0.284 0.716
L41 Parapsoriasis
0.000 0.284 0.716
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.284 0.716
M07.5 Arthropathy in ulcerative colitis
0.000 0.284 0.716
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.284 0.716
M07.2 Psoriatic spondylitis
0.000 0.284 0.716
M07.1 Arthritis mutilans
0.000 0.284 0.716
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.284 0.716
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.284 0.716
M07.38 Other psoriatic arthropathies (Other)
0.000 0.285 0.715
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.285 0.715
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.285 0.715
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.285 0.715
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.285 0.715
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.285 0.715
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.285 0.715
L40.0 Psoriasis vulgaris
0.000 0.285 0.715
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.714 0.286 0.000
G37.5 Concentric sclerosis [Balo]
0.713 0.287 0.000
G37.4 Subacute necrotising myelitis
0.713 0.287 0.000
G37.2 Central pontine myelinolysis
0.713 0.287 0.000
G37.1 Central demyelination of corpus callosum
0.713 0.287 0.000
G37.0 Diffuse sclerosis
0.713 0.287 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.287 0.713
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.287 0.713
M35.5 Multifocal fibrosclerosis
0.000 0.287 0.713
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.287 0.713
I00-I02 Acute rheumatic fever
0.000 0.287 0.713
I13 Hypertensive heart and renal disease
0.000 0.288 0.711
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.289 0.711
M65.1 Other infective (teno)synovitis
0.000 0.289 0.711
H40.5 Glaucoma secondary to other eye disorders
0.000 0.290 0.710
E88.2 Lipomatosis, not elsewhere classified
0.000 0.290 0.710
M31 Other necrotising vasculopathies
0.000 0.291 0.709
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.291 0.709
E88.8 Other specified metabolic disorders
0.000 0.291 0.709
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.292 0.708
M14 Arthropathies in other diseases classified elsewhere
0.000 0.292 0.708
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.292 0.708
H43-H45 Disorders of vitreous body and globe
0.000 0.293 0.707
L43.3 Subacute (active) lichen planus
0.000 0.296 0.703
L43.2 Lichenoid drug reaction
0.000 0.296 0.703
L43.1 Bullous lichen planus
0.000 0.296 0.703
L43.0 Hypertrophic lichen planus
0.000 0.296 0.703
H33 Retinal detachments and breaks
0.000 0.297 0.703
E70 Disorders of aromatic amino-acid metabolism
0.000 0.299 0.701
E06.5 Other chronic thyroiditis
0.000 0.302 0.698
E06.4 Drug-induced thyroiditis
0.000 0.302 0.698
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.302 0.698
E06.1 Subacute thyroiditis
0.000 0.302 0.698
E06.0 Acute thyroiditis
0.000 0.302 0.698
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.302 0.698
M34.8 Other forms of systemic sclerosis
0.000 0.303 0.697
H35.7 Separation of retinal layers
0.000 0.304 0.696
E13 Other specified diabetes mellitus
0.000 0.305 0.695
E79 Disorders of purine and pyrimidine metabolism
0.000 0.307 0.693
M86-M90 Other osteopathies
0.000 0.309 0.691
H34.0 Transient retinal artery occlusion
0.000 0.310 0.690
H42 Glaucoma in diseases classified elsewhere
0.000 0.312 0.688
E11.6 With other specified complications
0.000 0.313 0.687
E07.8 Other specified disorders of thyroid
0.000 0.313 0.687
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)
0.000 0.313 0.687
I11 Hypertensive heart disease
0.000 0.314 0.686
Chapter VIII Diseases of the ear and mastoid process
0.000 0.315 0.685
E16.1 Other hypoglycaemia
0.000 0.317 0.683
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.318 0.682
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.318 0.682
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.318 0.682
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.318 0.682
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.318 0.682
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.318 0.682
H40.1 Primary open-angle glaucoma
0.000 0.320 0.680
M34.2 Systemic sclerosis induced by drugs and chemicals
0.000 0.320 0.680
M34.0 Progressive systemic sclerosis
0.000 0.320 0.680
M12 Other specific arthropathies
0.000 0.322 0.678
M91-M94 Chondropathies
0.000 0.324 0.676
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.325 0.675
M06.38 Rheumatoid nodule (Other)
0.000 0.325 0.675
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.325 0.675
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.325 0.675
M06.33 Rheumatoid nodule (Forearm)
0.000 0.325 0.675
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.325 0.675
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.325 0.675
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.327 0.672
H40.6 Glaucoma secondary to drugs
0.000 0.328 0.672
H40.3 Glaucoma secondary to eye trauma
0.000 0.328 0.672
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.330 0.670
M07.6 Other enteropathic arthropathies
0.000 0.331 0.669
E06.9 Thyroiditis, unspecified
0.000 0.331 0.668
E78.4 Other hyperlipidaemia
0.000 0.332 0.668
E84 Cystic fibrosis
0.000 0.333 0.667
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.336 0.664
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.336 0.664
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.336 0.664
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.336 0.664
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.336 0.664
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.336 0.664
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.338 0.662
E72 Other disorders of amino-acid metabolism
0.000 0.340 0.660
M65.2 Calcific tendinitis
0.000 0.340 0.659
M65.0 Abscess of tendon sheath
0.000 0.340 0.659
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.343 0.656
M49 Spondylopathies in diseases classified elsewhere
0.000 0.344 0.656
H60-H62 Diseases of external ear
0.000 0.347 0.653
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.348 0.652
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.348 0.652
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.348 0.652
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.348 0.652
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.348 0.652
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.348 0.652
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.348 0.652
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.348 0.652
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.349 0.651
E11.4 With neurological complications
0.000 0.350 0.650
H35.2 Other proliferative retinopathy
0.000 0.352 0.648
M32 Systemic lupus erythematosus
0.000 0.355 0.645
M65.98 Synovitis and tenosynovitis, unspecified (Other)
0.000 0.356 0.644
M66 Spontaneous rupture of synovium and tendon
0.000 0.357 0.643
E88.3 Tumour lysis syndrome
0.000 0.358 0.642
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)
0.000 0.358 0.642
M86 Osteomyelitis
0.000 0.361 0.638
E07.1 Dyshormogenetic goitre
0.000 0.362 0.638
E07.0 Hypersecretion of calcitonin
0.000 0.362 0.638
E88.9 Metabolic disorder, unspecified
0.000 0.362 0.637
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.362 0.637
D62 Acute posthaemorrhagic anaemia
0.000 0.363 0.637
I15.9 Seconday hypertension, unspecified
0.000 0.365 0.635
I15.1 Hypertension secondary to other renal disorders
0.000 0.366 0.634
H35.1 Retinopathy of prematurity
0.000 0.369 0.631
M11 Other crystal arthropathies
0.000 0.370 0.630
H33.3 Retinal breaks without detachment
0.000 0.372 0.628
H40.0 Glaucoma suspect
0.000 0.373 0.627
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec
0.000 0.374 0.626
M65.48 Radial styloid tenosynovitis [de Quervain]-Other
0.000 0.374 0.626
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot
0.000 0.374 0.626
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg
0.000 0.374 0.626
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh
0.000 0.374 0.626
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm
0.000 0.374 0.626
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region
0.000 0.374 0.626
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)
0.000 0.374 0.626
H43 Disorders of vitreous body
0.000 0.377 0.623
M10 Gout
0.000 0.377 0.623
L10-L14 Bullous disorders
0.000 0.379 0.621
L42 Pityriasis rosea
0.000 0.381 0.619
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.383 0.617
E89.4 Postprocedural ovarian failure
0.000 0.384 0.616
E05.8 Other thyrotoxicosis
0.000 0.389 0.611
M86.9 Osteomyelitis, unspecified
0.000 0.391 0.609
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.391 0.609
E73 Lactose intolerance
0.000 0.391 0.608
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.000 0.396 0.604
H61 Other disorders of external ear
0.000 0.399 0.601
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.000 0.405 0.595
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.405 0.595
M30.0 Polyarteritis nodosa
0.000 0.406 0.594
I23 Certain current complications following acute myocardial infarction
0.000 0.407 0.593
L55 Sunburn
0.000 0.408 0.592
E65-E68 Obesity and other hyperalimentation
0.000 0.409 0.591
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.412 0.588
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.412 0.588
E89.5 Postprocedural testicular hypofunction
0.000 0.412 0.588
E89.1 Postprocedural hypoinsulinaemia
0.000 0.412 0.588
M60-M63 Disorders of muscles
0.000 0.414 0.586
D64.4 Congenital dyserythropoietic anaemia
0.000 0.416 0.583
D64.3 Other sideroblastic anaemias
0.000 0.416 0.583
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.416 0.583
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.416 0.583
D64.0 Hereditary sideroblastic anaemia
0.000 0.416 0.583
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.418 0.582
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.419 0.581
M33 Dermatopolymyositis
0.000 0.420 0.579
I15.8 Other secondary hypertension
0.000 0.420 0.579
I15.2 Hypertension secondary to endocrine disorders
0.000 0.420 0.579
L20-L30 Dermatitis and eczema
0.000 0.421 0.579
I15.0 Renovascular hypertension
0.000 0.421 0.579
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.421 0.579
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.421 0.579
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.421 0.579
E74.2 Disorders of galactose metabolism
0.000 0.421 0.579
E74.1 Disorders of fructose metabolism
0.000 0.421 0.579
E74.0 Glycogen storage disease
0.000 0.421 0.579
M80-M85 Disorders of bone density and structure
0.000 0.423 0.577
I12.0 Hypertensive renal disease with renal failure
0.000 0.427 0.573
M15-M19 Arthrosis
0.000 0.428 0.572
H60 Otitis externa
0.000 0.428 0.572
M31.6 Other giant cell arteritis
0.000 0.429 0.571
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.431 0.569
M35.0 Sicca syndrome [Sjogren]
0.000 0.431 0.569
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.434 0.566
M14.6 Neuropathic arthropathy
0.000 0.435 0.565
H33.4 Traction detachment of retina
0.000 0.435 0.565
E89.3 Postprocedural hypopituitarism
0.000 0.437 0.563
E03.1 Congenital hypothyroidism without goitre
0.000 0.437 0.562
M65.14 Other infective (teno)synovitis (Hand)
0.000 0.439 0.561
M30.8 Other conditions related to polyarteritis nodosa
0.000 0.441 0.559
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]
0.000 0.441 0.559
M30.2 Juvenile polyarteritis
0.000 0.441 0.559
I21 Acute myocardial infarction
0.000 0.441 0.559
M00-M03 Infectious arthropathies
0.000 0.441 0.558
L28 Lichen simplex chronicus and prurigo
0.000 0.442 0.558
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.452 0.548
I70 Atherosclerosis
0.000 0.455 0.545
L57.5 Actinic granuloma
0.000 0.455 0.545
L57.3 Poikiloderma of Civatte
0.000 0.455 0.545
L57.2 Cutis rhomboidalis nuchae
0.000 0.455 0.545
L57.1 Actinic reticuloid
0.000 0.455 0.545
H43.3 Other vitreous opacities
0.000 0.455 0.545
E20-E35 Disorders of other endocrine glands
0.000 0.457 0.543
H61.0 Perichondritis of external ear
0.000 0.457 0.543
E11.0 With coma
0.000 0.458 0.542
E83.8 Other disorders of mineral metabolism
0.220 0.458 0.322
E83.2 Disorders of zinc metabolism
0.220 0.458 0.322
E83.0 Disorders of copper metabolism
0.220 0.458 0.322
L58 Radiodermatitis
0.000 0.459 0.541
E78.8 Other disorders of lipoprotein metabolism
0.000 0.461 0.539
G36.0 Neuromyelitis optica [Devic]
0.536 0.464 0.000
D55-D59 Haemolytic anaemias
0.000 0.464 0.536
M31.3 Wegener's granulomatosis
0.000 0.464 0.536
L28.0 Lichen simplex chronicus
0.000 0.467 0.533
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.469 0.531
H61.8 Other specified disorders of external ear
0.000 0.470 0.530
H46 Optic neuritis
0.000 0.470 0.530
H43.9 Disorder of vitreous body, unspecified
0.000 0.473 0.527
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.474 0.526
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.477 0.523
E83.9 Disorder of mineral metabolism, unspecified
0.238 0.477 0.286
G36.9 Acute disseminated demyelination, unspecified
0.522 0.478 0.000
G36.8 Other specified acute disseminated demyelination
0.522 0.478 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.522 0.478 0.000
E89.2 Postprocedural hypoparathyroidism
0.000 0.478 0.522
H30.9 Chorioretinal inflammation, unspecified
0.000 0.478 0.522
I00 Rheumatic fever without mention of heart involvement
0.000 0.479 0.521
M18 Arthrosis of first carpometacarpal joint
0.000 0.479 0.521
M31.9 Necrotising vasculopathy, unspecified
0.000 0.481 0.519
M82 Osteoporosis in diseases classified elsewhere
0.000 0.481 0.519
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.482 0.518
H30.8 Other chorioretinal inflammations
0.000 0.483 0.516
H30.2 Posterior cyclitis
0.000 0.483 0.516
H30.1 Disseminated chorioretinal inflammation
0.000 0.483 0.516
H30.0 Focal chorioretinal inflammation
0.000 0.483 0.516
E46 Unspecified protein-energy malnutrition
0.000 0.483 0.517
M31.1 Thrombotic microangiopathy
0.000 0.484 0.516
H61.1 Non-infective disorders of pinna
0.000 0.484 0.516
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.485 0.515
E45 Retarded development following protein-energy malnutrition
0.000 0.485 0.515
E43 Unspecified severe protein-energy malnutrition
0.000 0.485 0.515
E42 Marasmic kwashiorkor
0.000 0.485 0.515
E41 Nutritional marasmus
0.000 0.485 0.515
E40 Kwashiorkor
0.000 0.485 0.515
H35.5 Hereditary retinal dystrophy
0.000 0.486 0.514
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.486 0.514
M06.18 Adult-onset Still's disease (Other)
0.000 0.486 0.514
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.486 0.514
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.486 0.514
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.486 0.514
M06.14 Adult-onset Still's disease (Hand)
0.000 0.486 0.514
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.486 0.514
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.486 0.514
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.486 0.514
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.486 0.514
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.486 0.514
M06.28 Rheumatoid bursitis (Other)
0.000 0.486 0.514
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.486 0.514
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.486 0.514
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.486 0.514
M06.24 Rheumatoid bursitis (Hand)
0.000 0.486 0.514
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.486 0.514
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.486 0.514
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.486 0.514
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.486 0.514
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.486 0.514
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.486 0.514
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.486 0.514
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.486 0.514
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.486 0.514
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.486 0.514
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.486 0.514

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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