TreeWAS – Variant ID: rs9274552

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.000	1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.000	1.000
D64.9 Anaemia, unspecified	0.000	0.000	1.000
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
E05.9 Thyrotoxicosis, unspecified	0.000	0.000	1.000
E10.9 Without complications	0.000	0.000	1.000
E10.3 With ophthalmic complications	0.000	0.000	1.000
E10.1 With ketoacidosis	0.000	0.000	1.000
E11.9 Without complications	0.000	0.000	1.000
E16.2 Hypoglycaemia, unspecified	0.000	0.000	1.000
H36.0 Diabetic retinopathy	0.000	0.000	1.000
J33.9 Nasal polyp, unspecified	0.000	0.000	1.000
J45.9 Asthma, unspecified	0.000	0.000	1.000
K51.9 Ulcerative colitis, unspecified	1.000	0.000	0.000
K90.0 Coeliac disease	0.000	0.000	1.000
M06.9 Rheumatoid arthritis, unspecified	0.000	0.000	1.000
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.000	1.000
E14 Unspecified diabetes mellitus	0.000	0.000	1.000
E11 Non-insulin-dependent diabetes mellitus	0.000	0.000	1.000
E10 Insulin-dependent diabetes mellitus	0.000	0.000	1.000
G35 Multiple sclerosis	1.000	0.000	0.000
K51 Ulcerative colitis	1.000	0.000	0.000
E10-E14 Diabetes mellitus	0.000	0.000	1.000
E00-E07 Disorders of thyroid gland	0.000	0.000	1.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.000	1.000
# Top node	0.000	0.000	1.000
N48 Other disorders of penis	0.000	0.000	1.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.000	1.000
E10.4 With neurological complications	0.000	0.000	1.000
E11.3 With ophthalmic complications	0.000	0.000	1.000
E14.9 Without complications	0.000	0.000	1.000
E03 Other hypothyroidism	0.000	0.000	1.000
E16 Other disorders of pancreatic internal secretion	0.000	0.000	1.000
J33 Nasal polyp	0.000	0.000	1.000
E14.3 With ophthalmic complications	0.000	0.000	1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.000	1.000
M06 Other rheumatoid arthritis	0.000	0.000	1.000
Chapter XI Diseases of the digestive system	0.000	0.000	1.000
N40-N51 Diseases of male genital organs	0.000	0.000	1.000
D50-D53 Nutritional anaemias	0.000	0.000	1.000
J45 Asthma	0.000	0.000	1.000
L80-L99 Other disorders of the skin and subcutaneous tissue	0.000	0.000	1.000
K70-K77 Diseases of liver	0.000	0.000	1.000
D00-D09 In situ neoplasms	0.000	0.000	1.000
Chapter II Neoplasms	0.000	0.000	1.000
C21 Malignant neoplasm of anus and anal canal	0.000	0.000	1.000
M05-M14 Inflammatory polyarthropathies	0.000	0.000	1.000
N47 Redundant prepuce, phimosis and paraphimosis	0.000	0.000	1.000
J40-J47 Chronic lower respiratory diseases	0.000	0.001	0.999
K90 Intestinal malabsorption	0.000	0.001	0.999
M05 Seropositive rheumatoid arthritis	0.000	0.001	0.999
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.001	0.999
Chapter XII Diseases of the skin and subcutaneous tissue	0.000	0.001	0.999
C15-C26 Malignant neoplasms of digestive organs	0.000	0.001	0.999
K75 Other inflammatory liver diseases	0.000	0.001	0.999
J33.0 Polyp of nasal cavity	0.000	0.001	0.999
Chapter XIV Diseases of the genitourinary system	0.000	0.001	0.999
D64 Other anaemias	0.000	0.001	0.999
Chapter X Diseases of the respiratory system	0.000	0.001	0.999
N00-N08 Glomerular diseases	0.000	0.001	0.999
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.001	0.999
D07 Carcinoma in situ of other and unspecified genital organs	0.000	0.001	0.999
L97 Ulcer of lower limb, not elsewhere classified	0.000	0.001	0.999
L90 Atrophic disorders of skin	0.000	0.001	0.999
D60-D64 Aplastic and other anaemias	0.000	0.001	0.999
K75.4 Autoimmune hepatitis	0.000	0.001	0.999
K90-K93 Other diseases of the digestive system	0.000	0.001	0.999
L90.0 Lichen sclerosus et atrophicus	0.000	0.001	0.999
D50 Iron deficiency anaemia	0.000	0.001	0.999
D07.1 Vulva	0.000	0.001	0.999
C21.0 Anus, unspecified	0.000	0.002	0.998
D06 Carcinoma in situ of cervix uteri	0.000	0.002	0.998
N48.6 Balanitis xerotica obliterans	0.000	0.002	0.998
D50.9 Iron deficiency anaemia, unspecified	0.000	0.003	0.997
H36 Retinal disorders in diseases classified elsewhere	0.000	0.003	0.997
D06.9 Cervix, unspecified	0.000	0.004	0.996
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.004	0.996
L92 Granulomatous disorders of skin and subcutaneous tissue	0.000	0.005	0.995
H30-H36 Disorders of choroid and retina	0.000	0.005	0.995
E83.1 Disorders of iron metabolism	0.995	0.005	0.000
E20-E35 Disorders of other endocrine glands	0.000	0.005	0.995
E10.5 With peripheral circulatory complications	0.000	0.005	0.995
K51.4 Pseudopolyposis of colon	0.994	0.006	0.000
Chapter VII Diseases of the eye and adnexa	0.000	0.006	0.994
N48.1 Balanoposthitis	0.000	0.006	0.994
C21.1 Anal canal	0.000	0.008	0.992
N08 Glomerular disorders in diseases classified elsewhere	0.000	0.009	0.991
E11.1 With ketoacidosis	0.000	0.010	0.990
N05 Unspecified nephritic syndrome	0.000	0.010	0.990
N08.3 Glomerular disorders in diabetes mellitus	0.000	0.012	0.988
H43-H45 Disorders of vitreous body and globe	0.000	0.012	0.988
E27 Other disorders of adrenal gland	0.000	0.013	0.987
K51.3 Ulcerative (chronic) rectosigmoiditis	0.987	0.013	0.000
Chapter IX Diseases of the circulatory system	0.000	0.014	0.986
I20-I25 Ischaemic heart diseases	0.000	0.014	0.986
D51 Vitamin B12 deficiency anaemia	0.000	0.014	0.986
H43 Disorders of vitreous body	0.000	0.015	0.985
L92.0 Granuloma annulare	0.000	0.016	0.984
E27.1 Primary adrenocortical insufficiency	0.000	0.017	0.983
J46 Status asthmaticus	0.000	0.017	0.983
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.018	0.982
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.018	0.982
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.018	0.982
J33.8 Other polyp of sinus	0.000	0.021	0.979
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.023	0.977
K51.2 Ulcerative (chronic) proctitis	0.977	0.023	0.000
H43.1 Vitreous haemorrhage	0.000	0.023	0.977
C20 Malignant neoplasm of rectum	0.000	0.026	0.974
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.000	0.026	0.974
E10.2 With renal complications	0.000	0.028	0.972
I20 Angina pectoris	0.000	0.029	0.971
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.032	0.968
N48.0 Leukoplakia of penis	0.000	0.033	0.967
E07 Other disorders of thyroid	0.000	0.033	0.967
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.034	0.966
E10.0 With coma	0.000	0.036	0.964
E10.6 With other specified complications	0.000	0.037	0.963
E11.5 With peripheral circulatory complications	0.000	0.039	0.961
Chapter VI Diseases of the nervous system	0.000	0.041	0.959
E10.8 With unspecified complications	0.000	0.042	0.958
L40-L45 Papulosquamous disorders	0.000	0.042	0.958
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.000	0.042	0.958
I25 Chronic ischaemic heart disease	0.000	0.046	0.954
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.000	0.047	0.953
I20.9 Angina pectoris, unspecified	0.000	0.048	0.952
J95-J99 Other diseases of the respiratory system	0.000	0.048	0.952
I24 Other acute ischaemic heart diseases	0.000	0.049	0.951
E07.9 Disorder of thyroid, unspecified	0.000	0.050	0.950
N04 Nephrotic syndrome	0.000	0.051	0.949
G63 Polyneuropathy in diseases classified elsewhere	0.000	0.058	0.942
K55-K64 Other diseases of intestines	0.000	0.059	0.941
L40 Psoriasis	0.000	0.059	0.941
H34 Retinal vascular occlusions	0.000	0.059	0.941
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.000	0.061	0.939
E11.2 With renal complications	0.000	0.061	0.939
K60 Fissure and fistula of anal and rectal regions	0.000	0.062	0.938
C09 Malignant neoplasm of tonsil	0.000	0.064	0.936
K60.2 Anal fissure, unspecified	0.000	0.064	0.936
L80 Vitiligo	0.000	0.065	0.935
K51.8 Other ulcerative colitis	0.935	0.065	0.000
L40.9 Psoriasis, unspecified	0.000	0.065	0.935
G63.2 Diabetic polyneuropathy	0.000	0.066	0.934
C91.1 Chronic lymphocytic leukaemia	0.000	0.067	0.933
M06.3 Rheumatoid nodule	0.000	0.069	0.931
N49.2 Inflammatory disorders of scrotum	0.000	0.069	0.931
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.070	0.930
J30-J39 Other diseases of upper respiratory tract	0.000	0.072	0.928
K73 Chronic hepatitis, not elsewhere classified	0.000	0.072	0.928
D50.8 Other iron deficiency anaemias	0.000	0.072	0.928
K51.5 Mucosal proctocolitis	0.926	0.074	0.000
C91 Lymphoid leukaemia	0.000	0.074	0.926
I25.5 Ischaemic cardiomyopathy	0.000	0.074	0.926
J44 Other chronic obstructive pulmonary disease	0.000	0.075	0.925
K72 Hepatic failure, not elsewhere classified	0.000	0.076	0.924
I20.0 Unstable angina	0.000	0.077	0.923
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.077	0.923
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.000	0.080	0.920
K90.9 Intestinal malabsorption, unspecified	0.000	0.084	0.916
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.084	0.916
H43.3 Other vitreous opacities	0.000	0.085	0.915
K75.8 Other specified inflammatory liver diseases	0.000	0.088	0.912
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.000	0.088	0.912
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.000	0.088	0.912
G35-G37 Demyelinating diseases of the central nervous system	0.836	0.089	0.075
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.000	0.089	0.911
H34.8 Other retinal vascular occlusions	0.000	0.090	0.910
E24 Cushing's syndrome	0.000	0.090	0.910
C09.9 Tonsil, unspecified	0.000	0.091	0.909
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.092	0.908
K55 Vascular disorders of intestine	0.000	0.093	0.907
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.000	0.095	0.905
E11.6 With other specified complications	0.000	0.096	0.904
E13 Other specified diabetes mellitus	0.000	0.096	0.904
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.097	0.903
I74 Arterial embolism and thrombosis	0.000	0.097	0.903
N05.2 Diffuse membranous glomerulonephritis	0.000	0.099	0.901
J45.0 Predominantly allergic asthma	0.000	0.099	0.901
G50-G59 Nerve, nerve root and plexus disorders	0.000	0.100	0.900
E16.1 Other hypoglycaemia	0.000	0.103	0.897
K55.2 Angiodysplasia of colon	0.000	0.103	0.897
I10-I15 Hypertensive diseases	0.000	0.103	0.897
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.000	0.105	0.895
M06.4 Inflammatory polyarthropathy	0.000	0.112	0.888
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.112	0.888
E06 Thyroiditis	0.000	0.112	0.888
J98 Other respiratory disorders	0.000	0.115	0.885
N04.9 Unspecified	0.000	0.116	0.884
N05.1 Focal and segmental glomerular lesions	0.000	0.117	0.883
E21.0 Primary hyperparathyroidism	0.000	0.117	0.883
L10-L14 Bullous disorders	0.000	0.123	0.877
G56 Mononeuropathies of upper limb	0.000	0.125	0.875
G56.0 Carpal tunnel syndrome	0.000	0.125	0.875
N48.4 Impotence of organic origin	0.000	0.126	0.874
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.129	0.871
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.131	0.869
J98.0 Diseases of bronchus, not elsewhere classified	0.000	0.131	0.869
E50-E64 Other nutritional deficiencies	0.000	0.133	0.867
E21.3 Hyperparathyroidism, unspecified	0.000	0.134	0.866
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.000	0.140	0.860
G00-G09 Inflammatory diseases of the central nervous system	0.000	0.142	0.858
G70-G73 Diseases of myoneural junction and muscle	0.000	0.143	0.857
J86 Pyothorax	0.000	0.143	0.857
N05.5 Diffuse mesangiocapillary glomerulonephritis	0.000	0.145	0.855
K60.0 Acute anal fissure	0.000	0.145	0.855
H43.8 Other disorders of vitreous body	0.000	0.146	0.854
I77 Other disorders of arteries and arterioles	0.000	0.146	0.854
E14.1 With ketoacidosis	0.000	0.147	0.853
D01 Carcinoma in situ of other and unspecified digestive organs	0.000	0.147	0.853
E14.8 With unspecified complications	0.000	0.148	0.852
I10 Essential (primary) hypertension	0.000	0.151	0.849
K73.2 Chronic active hepatitis, not elsewhere classified	0.000	0.151	0.849
D07.4 Penis	0.000	0.152	0.848
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.000	0.153	0.847
M45-M49 Spondylopathies	0.000	0.155	0.845
E03.8 Other specified hypothyroidism	0.000	0.157	0.843
I74.5 Embolism and thrombosis of iliac artery	0.000	0.157	0.843
E06.3 Autoimmune thyroiditis	0.000	0.159	0.841
N05.9 Unspecified	0.000	0.161	0.839
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.161	0.839
I74.8 Embolism and thrombosis of other arteries	0.000	0.162	0.838
E53 Deficiency of other B group vitamins	0.000	0.164	0.836
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.165	0.835
N48.2 Other inflammatory disorders of penis	0.000	0.165	0.835
K57 Diverticular disease of intestine	0.000	0.165	0.835
N05.8 Other	0.000	0.166	0.834
K57.3 Diverticular disease of large intestine without perforation or abscess	0.000	0.171	0.829
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.171	0.829
E13.9 Without complications	0.000	0.172	0.828
E14.5 With peripheral circulatory complications	0.000	0.172	0.827
K72.0 Acute and subacute hepatic failure	0.000	0.173	0.827
E14.6 With other specified complications	0.000	0.178	0.822
C23 Malignant neoplasm of gallbladder	0.000	0.178	0.822
M06.32 Rheumatoid nodule (Upper arm)	0.000	0.181	0.819
C22.9 Liver, unspecified	0.000	0.182	0.818
E53.8 Deficiency of other specified B group vitamins	0.000	0.182	0.818
M14 Arthropathies in other diseases classified elsewhere	0.000	0.183	0.817
G59 Mononeuropathy in diseases classified elsewhere	0.000	0.183	0.817
E20 Hypoparathyroidism	0.000	0.186	0.814
J86.0 Pyothorax with fistula	0.000	0.186	0.814
K60.1 Chronic anal fissure	0.000	0.190	0.810
K51.0 Ulcerative (chronic) enterocolitis	0.810	0.190	0.000
G61 Inflammatory polyneuropathy	0.000	0.190	0.810
K74 Fibrosis and cirrhosis of liver	0.000	0.193	0.807
G60 Hereditary and idiopathic neuropathy	0.000	0.194	0.806
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.195	0.805
I25.1 Atherosclerotic heart disease	0.000	0.196	0.804
G00 Bacterial meningitis, not elsewhere classified	0.000	0.197	0.803
G37 Other demyelinating diseases of central nervous system	0.780	0.198	0.022
C21.8 Overlapping lesion of rectum, anus and anal canal	0.000	0.200	0.800
E14.4 With neurological complications	0.000	0.205	0.795
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.205	0.795
E14.2 Withrenal complications	0.000	0.208	0.792
C07 Malignant neoplasm of parotid gland	0.000	0.209	0.791
C04 Malignant neoplasm of floor of mouth	0.000	0.209	0.791
E27.2 Addisonian crisis	0.000	0.211	0.789
M10 Gout	0.000	0.211	0.788
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.000	0.214	0.786
M48 Other spondylopathies	0.000	0.215	0.785
K86 Other diseases of pancreas	0.000	0.218	0.782
G72 Other myopathies	0.000	0.218	0.782
N04.1 Focal and segmental glomerular lesions	0.000	0.219	0.781
I22 Subsequent myocardial infarction	0.000	0.220	0.780
E11.0 With coma	0.000	0.221	0.779
I77.6 Arteritis, unspecified	0.000	0.221	0.779
K75.3 Granulomatous hepatitis, not elsewhere classified	0.000	0.223	0.777
G51 Facial nerve disorders	0.000	0.223	0.777
C10 Malignant neoplasm of oropharynx	0.000	0.224	0.776
D06.0 Endocervix	0.000	0.224	0.776
K72.9 Hepatic failure, unspecified	0.000	0.224	0.776
E24.0 Pituitary-dependent Cushing's disease	0.000	0.226	0.774
C12 Malignant neoplasm of pyriform sinus	0.000	0.228	0.772
M12 Other specific arthropathies	0.000	0.230	0.770
C22.1 Intrahepatic bile duct carcinoma	0.000	0.230	0.770
E24.9 Cushing's syndrome, unspecified	0.000	0.235	0.765
C83 Diffuse non-Hodgkin's lymphoma	0.000	0.235	0.765
D51.3 Other dietary vitamin B12 deficiency anaemia	0.000	0.236	0.764
J98.4 Other disorders of lung	0.000	0.237	0.763
C91.9 Lymphoid leukaemia, unspecified	0.000	0.237	0.763
I77.9 Disorder of arteries and arterioles, unspecified	0.000	0.238	0.762
J99 Respiratory disorders in diseases classified elsewhere	0.000	0.240	0.760
N48.5 Ulcer of penis	0.000	0.240	0.760
J44.9 Chronic obstructive pulmonary disease, unspecified	0.000	0.240	0.760
J95 Postprocedural respiratory disorders, not elsewhere classified	0.000	0.241	0.759
C11 Malignant neoplasm of nasopharynx	0.000	0.242	0.758
L95 Vasculitis limited to skin, not elsewhere classified	0.000	0.242	0.758
G59.0 Diabetic mononeuropathy	0.000	0.243	0.757
L13 Other bullous disorders	0.000	0.244	0.756
E05.8 Other thyrotoxicosis	0.000	0.244	0.756
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.245	0.754
I25.2 Old myocardial infarction	0.000	0.246	0.754
K55.8 Other vascular disorders of intestine	0.000	0.247	0.753
K86.3 Pseudocyst of pancreas	0.000	0.247	0.753
L94 Other localised connective tissue disorders	0.000	0.247	0.753
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.000	0.249	0.751
M06.30 Rheumatoid nodule (Multiple sites)	0.000	0.250	0.750
N51 Disorders of male genital organs in diseases classified elsewhere	0.000	0.251	0.749
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.000	0.252	0.748
J45.1 Nonallergic asthma	0.000	0.252	0.748
M48.0 Spinal stenosis	0.000	0.252	0.748
C02 Malignant neoplasm of other and unspecified parts of tongue	0.000	0.253	0.747
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.000	0.253	0.747
C83.3 Large cell (diffuse)	0.000	0.254	0.746
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.254	0.746
J43 Emphysema	0.000	0.256	0.744
G00.1 Pneumococcal meningitis	0.000	0.256	0.744
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.000	0.259	0.741
G37.9 Demyelinating disease of central nervous system, unspecified	0.736	0.260	0.003
L40.0 Psoriasis vulgaris	0.000	0.261	0.739
C13 Malignant neoplasm of hypopharynx	0.000	0.262	0.737
G70 Myasthenia gravis and other myoneural disorders	0.000	0.264	0.736
M45 Ankylosing spondylitis	0.000	0.266	0.734
D70-D77 Other diseases of blood and blood-forming organs	0.000	0.267	0.733
L40.1 Generalised pustular psoriasis	0.000	0.267	0.733
M14.6 Neuropathic arthropathy	0.000	0.268	0.732
C91.0 Acute lymphoblastic leukaemia	0.000	0.272	0.728
C01 Malignant neoplasm of base of tongue	0.000	0.272	0.728
N48.9 Disorder of penis, unspecified	0.000	0.272	0.728
L12 Pemphigoid	0.000	0.273	0.727
J98.6 Disorders of diaphragm	0.000	0.273	0.727
M06.8 Other specified rheumatoid arthritis	0.000	0.273	0.726
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.274	0.726
M05.2 Rheumatoid vasculitis	0.000	0.277	0.723
M06.37 Rheumatoid nodule (Ankle and foot)	0.000	0.277	0.723
E21.2 Other hyperparathyroidism	0.000	0.277	0.723
I15 Secondary hypertension	0.000	0.277	0.723
G72.0 Drug-induced myopathy	0.000	0.277	0.723
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.000	0.278	0.722
Z93.2 Ileostomy status	0.720	0.280	0.000
I20.1 Angina pectoris with documented spasm	0.000	0.281	0.719
M06.34 Rheumatoid nodule (Hand)	0.000	0.282	0.718
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.283	0.717
E05.5 Thyroid crisis or storm	0.000	0.283	0.717
E05.4 Thyrotoxicosis factitia	0.000	0.283	0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.283	0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.283	0.717
E10.7 With multiple complications	0.000	0.283	0.717
E11.7 With multiple complications	0.000	0.283	0.717
E14.7 With multiple complications	0.000	0.283	0.717
E14.0 With coma	0.000	0.283	0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.283	0.717
E00 Congenital iodine-deficiency syndrome	0.000	0.283	0.717
E12 Malnutrition-related diabetes mellitus	0.000	0.283	0.717
Chapter XVI Certain conditions originating in the perinatal period	0.000	0.283	0.717
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.283	0.717
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.283	0.717
E16.4 Abnormal secretion of gastrin	0.000	0.283	0.717
E16.3 Increased secretion of glucagon	0.000	0.283	0.717
E03.5 Myxoedema coma	0.000	0.283	0.717
E03.4 Atrophy of thyroid (acquired)	0.000	0.283	0.717
E03.3 Postinfectious hypothyroidism	0.000	0.283	0.717
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.283	0.717
E15 Nondiabetic hypoglycaemic coma	0.000	0.283	0.717
M06.2 Rheumatoid bursitis	0.000	0.283	0.717
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.000	0.283	0.717
L87 Transepidermal elimination disorders	0.000	0.283	0.717
L86 Keratoderma in diseases classified elsewhere	0.000	0.283	0.717
K77 Liver disorders in diseases classified elsewhere	0.000	0.283	0.717
C21.2 Cloacogenic zone	0.000	0.283	0.717
M09 Juvenile arthritis in diseases classified elsewhere	0.000	0.283	0.717
M08 Juvenile arthritis	0.000	0.283	0.717
K73.8 Other chronic hepatitis, not elsewhere classified	0.000	0.283	0.717
K90.3 Pancreatic steatorrhoea	0.000	0.283	0.717
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.283	0.717
K90.1 Tropical sprue	0.000	0.283	0.717
M05.8 Other seropositive rheumatoid arthritis	0.000	0.283	0.716
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.000	0.283	0.716
M05.1 Rheumatoid lung disease	0.000	0.283	0.716
M05.0 Felty's syndrome	0.000	0.283	0.716
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.283	0.716
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.283	0.716
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.283	0.716
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.283	0.716
K75.2 Nonspecific reactive hepatitis	0.000	0.284	0.716
K75.1 Phlebitis of portal vein	0.000	0.284	0.716
D64.4 Congenital dyserythropoietic anaemia	0.000	0.284	0.716
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.000	0.284	0.716
D64.1 Secondary sideroblastic anaemia due to disease	0.000	0.284	0.716
D64.0 Hereditary sideroblastic anaemia	0.000	0.284	0.716
N05.7 Diffuse crescentic glomerulonephritis	0.000	0.284	0.716
N07 Hereditary nephropathy, not elsewhere classified	0.000	0.284	0.716
N06 Isolated proteinuria with specified morphological lesion	0.000	0.284	0.716
N01 Rapidly progressive nephritic syndrome	0.000	0.284	0.716
N00 Acute nephritic syndrome	0.000	0.284	0.716
D07.6 Other and unspecified male genital organs	0.000	0.284	0.716
D07.3 Other and unspecified female genital organs	0.000	0.284	0.716
D07.0 Endometrium	0.000	0.284	0.716
L90.9 Atrophic disorder of skin, unspecified	0.000	0.284	0.716
L90.6 Striae atrophicae	0.000	0.284	0.716
L90.4 Acrodermatitis chronica atrophicans	0.000	0.284	0.716
L90.3 Atrophoderma of Pasini and Pierini	0.000	0.284	0.716
L90.2 Anetoderma of Jadassohn-Pellizzari	0.000	0.284	0.716
L90.1 Anetoderma of Schweninger-Buzzi	0.000	0.284	0.716
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.000	0.284	0.716
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.284	0.716
D50.1 Sideropenic dysphagia	0.000	0.284	0.716
D06.7 Other parts of cervix	0.000	0.284	0.715
D06.1 Exocervix	0.000	0.284	0.715
H36.8 Other retinal disorders in diseases classified elsewhere	0.000	0.285	0.715
K86.1 Other chronic pancreatitis	0.000	0.285	0.715
K73.9 Chronic hepatitis, unspecified	0.000	0.285	0.715
D63 Anaemia in chronic diseases classified elsewhere	0.000	0.286	0.714
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.286	0.714
L92.2 Granuloma faciale [eosinophilic granuloma of skin]	0.000	0.286	0.714
L92.1 Necrobiosis lipoidica, not elsewhere classified	0.000	0.286	0.714
H32 Chorioretinal disorders in diseases classified elsewhere	0.000	0.286	0.714
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.286	0.713
E32 Diseases of thymus	0.000	0.286	0.713
E31 Polyglandular dysfunction	0.000	0.286	0.713
E30 Disorders of puberty, not elsewhere classified	0.000	0.286	0.713
H30 Chorioretinal inflammation	0.000	0.287	0.712
N08.8 Glomerular disorders in other diseases classified elsewhere	0.000	0.289	0.711
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism	0.000	0.289	0.711
N08.1 Glomerular disorders in neoplastic diseases	0.000	0.289	0.711
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere	0.000	0.289	0.711
D07.2 Vagina	0.000	0.290	0.710
E21.4 Other specified disorders of parathyroid gland	0.000	0.290	0.710
N05.6 Dense deposit disease	0.000	0.290	0.709
N05.4 Diffuse endocapillary proliferative glomerulonephritis	0.000	0.290	0.709
N05.0 Minor glomerular abnormality	0.000	0.290	0.709
N04.2 Diffuse membranous glomerulonephritis	0.000	0.291	0.709
I24.8 Other forms of acute ischaemic heart disease	0.000	0.291	0.709
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.000	0.292	0.708
D01.3 Anus and anal canal	0.000	0.292	0.708
E27.5 Adrenomedullary hyperfunction	0.000	0.292	0.708
E27.0 Other adrenocortical overactivity	0.000	0.292	0.708
D51.8 Other vitamin B12 deficiency anaemias	0.000	0.293	0.707
D51.2 Transcobalamin II deficiency	0.000	0.293	0.707
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.000	0.293	0.707
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.293	0.707
G61.0 Guillain-Barre syndrome	0.000	0.294	0.706
M10.9 Gout, unspecified	0.000	0.294	0.706
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.294	0.706
H25-H28 Disorders of lens	0.000	0.294	0.706
N44 Torsion of testis	0.000	0.295	0.705
M20-M25 Other joint disorders	0.000	0.297	0.703
C95 Leukaemia of unspecified cell type	0.000	0.297	0.702
E24.2 Drug-induced Cushing's syndrome	0.000	0.298	0.702
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens	0.000	0.301	0.698
M48.09 Spinal stenosis (Site unspecified)	0.000	0.302	0.698
L40.4 Guttate psoriasis	0.000	0.303	0.697
M35 Other systemic involvement of connective tissue	0.000	0.304	0.696
E11.8 With unspecified complications	0.000	0.305	0.695
I25.6 Silent myocardial ischaemia	0.000	0.305	0.695
D53 Other nutritional anaemias	0.000	0.305	0.694
K71 Toxic liver disease	0.000	0.306	0.694
C17 Malignant neoplasm of small intestine	0.000	0.306	0.694
E07.1 Dyshormogenetic goitre	0.000	0.307	0.693
E07.0 Hypersecretion of calcitonin	0.000	0.307	0.693
M35.3 Polymyalgia rheumatica	0.000	0.307	0.693
D01.0 Colon	0.000	0.310	0.690
H43.0 Vitreous prolapse	0.000	0.310	0.689
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.000	0.310	0.689
M31 Other necrotising vasculopathies	0.000	0.311	0.689
K82 Other diseases of gallbladder	0.000	0.312	0.688
C60-C63 Malignant neoplasms of male genital organs	0.000	0.312	0.688
H34.9 Retinal vascular occlusion, unspecified	0.000	0.313	0.687
E83 Disorders of mineral metabolism	0.686	0.313	0.001
L44 Other papulosquamous disorders	0.000	0.313	0.687
L41 Parapsoriasis	0.000	0.313	0.687
L45 Papulosquamous disorders in diseases classified elsewhere	0.000	0.313	0.687
N49.9 Inflammatory disorder of unspecified male genital organ	0.000	0.313	0.687
N49.0 Inflammatory disorders of seminal vesicle	0.000	0.313	0.687
K86.2 Cyst of pancreas	0.000	0.314	0.686
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.000	0.314	0.686
E20.9 Hypoparathyroidism, unspecified	0.000	0.316	0.684
M06.1 Adult-onset Still's disease	0.000	0.316	0.684
G64 Other disorders of peripheral nervous system	0.000	0.316	0.683
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.000	0.316	0.683
I00-I02 Acute rheumatic fever	0.000	0.317	0.683
K55.1 Chronic vascular disorders of intestine	0.000	0.317	0.683
J96 Respiratory failure, not elsewhere classified	0.000	0.318	0.682
J33.1 Polypoid sinus degeneration	0.000	0.319	0.681
N04.8 Other	0.000	0.320	0.680
N04.7 Diffuse crescentic glomerulonephritis	0.000	0.320	0.680
N04.6 Dense deposit disease	0.000	0.320	0.680
N04.5 Diffuse mesangiocapillary glomerulonephritis	0.000	0.320	0.680
N04.4 Diffuse endocapillary proliferative glomerulonephritis	0.000	0.320	0.680
N04.3 Diffuse mesangial proliferative glomerulonephritis	0.000	0.320	0.680
N04.0 Minor glomerular abnormality	0.000	0.320	0.680
G60.0 Hereditary motor and sensory neuropathy	0.000	0.320	0.680
G51.9 Disorder of facial nerve, unspecified	0.000	0.322	0.678
M31.6 Other giant cell arteritis	0.000	0.322	0.678
M49 Spondylopathies in diseases classified elsewhere	0.000	0.322	0.678
H43.2 Crystalline deposits in vitreous body	0.000	0.323	0.677
I77.8 Other specified disorders of arteries and arterioles	0.000	0.323	0.677
H31 Other disorders of choroid	0.000	0.323	0.677
E03.1 Congenital hypothyroidism without goitre	0.000	0.324	0.676
G63.8 Polyneuropathy in other diseases classified elsewhere	0.000	0.324	0.675
G63.6 Polyneuropathy in other musculoskeletal disorders	0.000	0.324	0.675
G63.5 Polyneuropathy in systemic connective tissue disorders	0.000	0.324	0.675
G63.4 Polyneuropathy in nutritional deficiency	0.000	0.324	0.675
G63.3 Polyneuropathy in other endocrine and metabolic diseases	0.000	0.324	0.675
G63.1 Polyneuropathy in neoplastic disease	0.000	0.324	0.675
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere	0.000	0.324	0.675
M48.06 Spinal stenosis (Lumbar region)	0.000	0.325	0.675
J45.8 Mixed asthma	0.000	0.325	0.675
K64 Haemorrhoids and perianal venous thrombosis	0.000	0.325	0.675
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess	0.000	0.325	0.675
L40.3 Pustulosis palmaris et plantaris	0.000	0.325	0.675
L40.2 Acrodermatitis continua	0.000	0.325	0.675

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations