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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9273215
log Bayes Factor = 440.214
Chromosome 6   position 32,613,712  (GRCh37) Explore rs9273215 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
D64.9 Anaemia, unspecified
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
J33.9 Nasal polyp, unspecified
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K51.9 Ulcerative colitis, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
K51 Ulcerative colitis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
N48 Other disorders of penis
0.000 0.000 1.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.000 1.000
E10.4 With neurological complications
0.000 0.000 1.000
E14.9 Without complications
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
J33 Nasal polyp
0.000 0.000 1.000
E11.3 With ophthalmic complications
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
E14.3 With ophthalmic complications
0.000 0.000 1.000
N40-N51 Diseases of male genital organs
0.000 0.000 1.000
Chapter XI Diseases of the digestive system
0.000 0.000 1.000
D50-D53 Nutritional anaemias
0.000 0.000 1.000
K70-K77 Diseases of liver
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
C21 Malignant neoplasm of anus and anal canal
0.000 0.000 1.000
Chapter II Neoplasms
0.000 0.000 1.000
N47 Redundant prepuce, phimosis and paraphimosis
0.000 0.000 1.000
D00-D09 In situ neoplasms
0.000 0.000 1.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.000 1.000
K90 Intestinal malabsorption
0.000 0.000 1.000
K75 Other inflammatory liver diseases
0.000 0.000 1.000
C15-C26 Malignant neoplasms of digestive organs
0.000 0.001 0.999
J33.0 Polyp of nasal cavity
0.000 0.001 0.999
K75.4 Autoimmune hepatitis
0.000 0.001 0.999
M05-M14 Inflammatory polyarthropathies
0.000 0.001 0.999
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.001 0.999
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.001 0.999
D64 Other anaemias
0.000 0.001 0.999
M05 Seropositive rheumatoid arthritis
0.000 0.001 0.999
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.001 0.999
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.001 0.999
D50 Iron deficiency anaemia
0.000 0.001 0.999
K90-K93 Other diseases of the digestive system
0.000 0.001 0.999
H36 Retinal disorders in diseases classified elsewhere
0.000 0.001 0.999
D60-D64 Aplastic and other anaemias
0.000 0.001 0.999
C21.0 Anus, unspecified
0.000 0.001 0.999
Chapter XIV Diseases of the genitourinary system
0.000 0.002 0.998
E83.1 Disorders of iron metabolism
0.998 0.002 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.000 0.002 0.998
L90 Atrophic disorders of skin
0.000 0.002 0.998
L90.0 Lichen sclerosus et atrophicus
0.000 0.002 0.998
N00-N08 Glomerular diseases
0.000 0.002 0.998
D50.9 Iron deficiency anaemia, unspecified
0.000 0.002 0.998
D07.1 Vulva
0.000 0.002 0.998
H30-H36 Disorders of choroid and retina
0.000 0.002 0.998
N48.6 Balanitis xerotica obliterans
0.000 0.003 0.997
Chapter VII Diseases of the eye and adnexa
0.000 0.003 0.997
E20-E35 Disorders of other endocrine glands
0.000 0.003 0.997
D06 Carcinoma in situ of cervix uteri
0.000 0.004 0.996
K51.4 Pseudopolyposis of colon
0.996 0.004 0.000
J45 Asthma
0.000 0.005 0.995
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.005 0.995
L92 Granulomatous disorders of skin and subcutaneous tissue
0.000 0.005 0.995
E10.5 With peripheral circulatory complications
0.000 0.005 0.995
C21.1 Anal canal
0.000 0.006 0.994
D06.9 Cervix, unspecified
0.000 0.007 0.993
N48.1 Balanoposthitis
0.000 0.007 0.993
H43-H45 Disorders of vitreous body and globe
0.000 0.007 0.993
E27 Other disorders of adrenal gland
0.000 0.008 0.992
H43 Disorders of vitreous body
0.000 0.009 0.991
E11.1 With ketoacidosis
0.000 0.009 0.991
E27.1 Primary adrenocortical insufficiency
0.000 0.010 0.990
N08 Glomerular disorders in diseases classified elsewhere
0.000 0.010 0.990
D51 Vitamin B12 deficiency anaemia
0.000 0.011 0.989
J40-J47 Chronic lower respiratory diseases
0.000 0.011 0.989
N05 Unspecified nephritic syndrome
0.000 0.012 0.988
Chapter X Diseases of the respiratory system
0.000 0.012 0.988
N08.3 Glomerular disorders in diabetes mellitus
0.000 0.013 0.987
K51.3 Ulcerative (chronic) rectosigmoiditis
0.986 0.014 0.000
L92.0 Granuloma annulare
0.000 0.016 0.984
H43.1 Vitreous haemorrhage
0.000 0.016 0.984
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.017 0.983
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.018 0.982
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.000 0.018 0.982
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.021 0.979
J33.8 Other polyp of sinus
0.000 0.023 0.977
K51.2 Ulcerative (chronic) proctitis
0.976 0.024 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.025 0.975
C20 Malignant neoplasm of rectum
0.000 0.026 0.974
E10.2 With renal complications
0.000 0.027 0.973
N48.0 Leukoplakia of penis
0.000 0.029 0.971
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.000 0.032 0.968
E10.0 With coma
0.000 0.035 0.965
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.037 0.963
J46 Status asthmaticus
0.000 0.037 0.963
Chapter VI Diseases of the nervous system
0.000 0.041 0.959
E10.6 With other specified complications
0.000 0.042 0.958
E11.5 With peripheral circulatory complications
0.000 0.044 0.956
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.044 0.956
C09 Malignant neoplasm of tonsil
0.000 0.047 0.953
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.000 0.048 0.952
E10.8 With unspecified complications
0.000 0.049 0.951
E07 Other disorders of thyroid
0.000 0.050 0.950
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.051 0.949
K51.8 Other ulcerative colitis
0.949 0.051 0.000
L80 Vitiligo
0.000 0.052 0.948
L40-L45 Papulosquamous disorders
0.000 0.053 0.947
H34 Retinal vascular occlusions
0.000 0.053 0.947
N49.2 Inflammatory disorders of scrotum
0.000 0.053 0.947
K72 Hepatic failure, not elsewhere classified
0.000 0.055 0.945
N04 Nephrotic syndrome
0.000 0.060 0.940
G63 Polyneuropathy in diseases classified elsewhere
0.000 0.060 0.940
K51.5 Mucosal proctocolitis
0.938 0.062 0.000
M06.3 Rheumatoid nodule
0.000 0.065 0.935
C09.9 Tonsil, unspecified
0.000 0.068 0.932
G63.2 Diabetic polyneuropathy
0.000 0.068 0.932
K73 Chronic hepatitis, not elsewhere classified
0.000 0.070 0.930
L40 Psoriasis
0.000 0.070 0.930
K90.9 Intestinal malabsorption, unspecified
0.000 0.071 0.929
E07.9 Disorder of thyroid, unspecified
0.000 0.073 0.927
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.000 0.074 0.926
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.077 0.923
L40.9 Psoriasis, unspecified
0.000 0.077 0.923
E11.2 With renal complications
0.000 0.080 0.920
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.083 0.917
H34.8 Other retinal vascular occlusions
0.000 0.083 0.917
J30-J39 Other diseases of upper respiratory tract
0.000 0.084 0.916
C91.1 Chronic lymphocytic leukaemia
0.000 0.086 0.914
H43.8 Other disorders of vitreous body
0.000 0.086 0.914
E24 Cushing's syndrome
0.000 0.087 0.913
K75.8 Other specified inflammatory liver diseases
0.000 0.092 0.908
J95-J99 Other diseases of the respiratory system
0.000 0.093 0.907
G35-G37 Demyelinating diseases of the central nervous system
0.822 0.095 0.082
E13 Other specified diabetes mellitus
0.000 0.096 0.904
D50.8 Other iron deficiency anaemias
0.000 0.096 0.904
C91 Lymphoid leukaemia
0.000 0.097 0.903
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.098 0.902
N05.2 Diffuse membranous glomerulonephritis
0.000 0.098 0.902
E06 Thyroiditis
0.000 0.099 0.901
E21.0 Primary hyperparathyroidism
0.000 0.101 0.899
E16.1 Other hypoglycaemia
0.000 0.101 0.899
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.105 0.895
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.106 0.894
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.106 0.894
G50-G59 Nerve, nerve root and plexus disorders
0.000 0.107 0.893
M06.4 Inflammatory polyarthropathy
0.000 0.110 0.890
H43.3 Other vitreous opacities
0.000 0.112 0.888
E50-E64 Other nutritional deficiencies
0.000 0.113 0.887
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.000 0.115 0.885
K55-K64 Other diseases of intestines
0.000 0.116 0.884
N05.1 Focal and segmental glomerular lesions
0.000 0.121 0.879
K60 Fissure and fistula of anal and rectal regions
0.000 0.121 0.879
G56.0 Carpal tunnel syndrome
0.000 0.121 0.879
G56 Mononeuropathies of upper limb
0.000 0.123 0.877
G00-G09 Inflammatory diseases of the central nervous system
0.000 0.124 0.876
L10-L14 Bullous disorders
0.000 0.125 0.875
Chapter IX Diseases of the circulatory system
0.000 0.125 0.875
N04.9 Unspecified
0.000 0.126 0.874
E11.6 With other specified complications
0.000 0.127 0.873
I20-I25 Ischaemic heart diseases
0.000 0.128 0.872
K60.2 Anal fissure, unspecified
0.000 0.128 0.872
E14.8 With unspecified complications
0.000 0.132 0.868
J45.0 Predominantly allergic asthma
0.000 0.133 0.867
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.133 0.867
K72.0 Acute and subacute hepatic failure
0.000 0.135 0.865
D07.4 Penis
0.000 0.136 0.864
E53 Deficiency of other B group vitamins
0.000 0.138 0.862
E21.3 Hyperparathyroidism, unspecified
0.000 0.140 0.860
N48.2 Other inflammatory disorders of penis
0.000 0.143 0.857
N48.4 Impotence of organic origin
0.000 0.143 0.857
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.000 0.144 0.856
D01 Carcinoma in situ of other and unspecified digestive organs
0.000 0.144 0.856
E06.3 Autoimmune thyroiditis
0.000 0.145 0.855
E14.1 With ketoacidosis
0.000 0.145 0.855
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.000 0.145 0.855
E03.8 Other specified hypothyroidism
0.000 0.147 0.853
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.150 0.850
G70-G73 Diseases of myoneural junction and muscle
0.000 0.150 0.850
K55 Vascular disorders of intestine
0.000 0.152 0.848
E53.8 Deficiency of other specified B group vitamins
0.000 0.152 0.848
I25 Chronic ischaemic heart disease
0.000 0.158 0.842
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.159 0.841
I24 Other acute ischaemic heart diseases
0.000 0.159 0.841
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.161 0.839
K55.2 Angiodysplasia of colon
0.000 0.163 0.837
N05.8 Other
0.000 0.165 0.835
J86 Pyothorax
0.000 0.166 0.834
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.171 0.829
K51.0 Ulcerative (chronic) enterocolitis
0.829 0.171 0.000
E14.5 With peripheral circulatory complications
0.000 0.171 0.829
E13.9 Without complications
0.000 0.171 0.829
C22.9 Liver, unspecified
0.000 0.172 0.828
M14 Arthropathies in other diseases classified elsewhere
0.000 0.172 0.828
I20 Angina pectoris
0.000 0.172 0.828
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.173 0.827
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.176 0.824
E14.6 With other specified complications
0.000 0.177 0.823
I25.5 Ischaemic cardiomyopathy
0.000 0.178 0.822
C23 Malignant neoplasm of gallbladder
0.000 0.179 0.821
G00 Bacterial meningitis, not elsewhere classified
0.000 0.180 0.820
N05.9 Unspecified
0.000 0.182 0.818
E20 Hypoparathyroidism
0.000 0.183 0.817
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.184 0.816
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.185 0.815
K72.9 Hepatic failure, unspecified
0.000 0.185 0.815
C04 Malignant neoplasm of floor of mouth
0.000 0.186 0.814
E27.2 Addisonian crisis
0.000 0.186 0.814
G59 Mononeuropathy in diseases classified elsewhere
0.000 0.187 0.813
E11.0 With coma
0.000 0.192 0.808
D04 Carcinoma in situ of skin
0.000 0.192 0.808
G61 Inflammatory polyneuropathy
0.000 0.194 0.806
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.194 0.806
I20.9 Angina pectoris, unspecified
0.000 0.195 0.805
G60 Hereditary and idiopathic neuropathy
0.000 0.195 0.805
M45-M49 Spondylopathies
0.000 0.197 0.803
I74 Arterial embolism and thrombosis
0.000 0.198 0.802
C21.8 Overlapping lesion of rectum, anus and anal canal
0.000 0.198 0.802
K60.0 Acute anal fissure
0.000 0.199 0.801
J98 Other respiratory disorders
0.000 0.199 0.801
K74 Fibrosis and cirrhosis of liver
0.000 0.199 0.801
E14.4 With neurological complications
0.000 0.203 0.797
C07 Malignant neoplasm of parotid gland
0.000 0.203 0.797
C10 Malignant neoplasm of oropharynx
0.000 0.204 0.796
E14.2 Withrenal complications
0.000 0.205 0.795
K60.1 Chronic anal fissure
0.000 0.208 0.792
C22.1 Intrahepatic bile duct carcinoma
0.000 0.208 0.792
J86.0 Pyothorax with fistula
0.000 0.213 0.787
G37 Other demyelinating diseases of central nervous system
0.762 0.213 0.025
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.213 0.787
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.216 0.784
J98.0 Diseases of bronchus, not elsewhere classified
0.000 0.216 0.784
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.216 0.784
K86 Other diseases of pancreas
0.000 0.219 0.781
M12 Other specific arthropathies
0.000 0.219 0.781
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.221 0.779
E24.0 Pituitary-dependent Cushing's disease
0.000 0.221 0.779
D06.0 Endocervix
0.000 0.223 0.777
G72 Other myopathies
0.000 0.228 0.772
E24.9 Cushing's syndrome, unspecified
0.000 0.232 0.768
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.233 0.767
L13 Other bullous disorders
0.000 0.233 0.767
C02 Malignant neoplasm of other and unspecified parts of tongue
0.000 0.237 0.763
C12 Malignant neoplasm of pyriform sinus
0.000 0.237 0.763
G51 Facial nerve disorders
0.000 0.238 0.762
G00.1 Pneumococcal meningitis
0.000 0.239 0.761
C11 Malignant neoplasm of nasopharynx
0.000 0.239 0.761
E05.8 Other thyrotoxicosis
0.000 0.241 0.759
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.243 0.757
L94 Other localised connective tissue disorders
0.000 0.244 0.756
G59.0 Diabetic mononeuropathy
0.000 0.244 0.756
N48.5 Ulcer of penis
0.000 0.245 0.755
I77 Other disorders of arteries and arterioles
0.000 0.245 0.755
K86.3 Pseudocyst of pancreas
0.000 0.245 0.755
I20.0 Unstable angina
0.000 0.245 0.755
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.245 0.755
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.246 0.754
N48.9 Disorder of penis, unspecified
0.000 0.246 0.754
N04.1 Focal and segmental glomerular lesions
0.000 0.248 0.752
L95 Vasculitis limited to skin, not elsewhere classified
0.000 0.248 0.752
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.249 0.751
K57 Diverticular disease of intestine
0.000 0.250 0.750
M06.8 Other specified rheumatoid arthritis
0.000 0.250 0.750
N51 Disorders of male genital organs in diseases classified elsewhere
0.000 0.250 0.750
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.251 0.749
J44 Other chronic obstructive pulmonary disease
0.000 0.252 0.748
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.252 0.748
M14.6 Neuropathic arthropathy
0.000 0.253 0.747
J45.1 Nonallergic asthma
0.000 0.254 0.746
I74.8 Embolism and thrombosis of other arteries
0.000 0.254 0.746
I74.5 Embolism and thrombosis of iliac artery
0.000 0.254 0.746
C13 Malignant neoplasm of hypopharynx
0.000 0.255 0.745
K57.3 Diverticular disease of large intestine without perforation or abscess
0.000 0.258 0.742
L40.1 Generalised pustular psoriasis
0.000 0.262 0.738
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.000 0.265 0.735
I25.2 Old myocardial infarction
0.000 0.268 0.732
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.270 0.730
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.271 0.729
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.271 0.729
L40.0 Psoriasis vulgaris
0.000 0.272 0.728
M06.34 Rheumatoid nodule (Hand)
0.000 0.273 0.727
G70 Myasthenia gravis and other myoneural disorders
0.000 0.274 0.726
L12 Pemphigoid
0.000 0.275 0.725
M05.2 Rheumatoid vasculitis
0.000 0.276 0.724
K73.9 Chronic hepatitis, unspecified
0.000 0.277 0.723
C60-C63 Malignant neoplasms of male genital organs
0.000 0.278 0.722
E21.2 Other hyperparathyroidism
0.000 0.278 0.722
G37.9 Demyelinating disease of central nervous system, unspecified
0.718 0.278 0.004
I10-I15 Hypertensive diseases
0.000 0.279 0.721
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.279 0.721
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.279 0.721
C01 Malignant neoplasm of base of tongue
0.000 0.280 0.720
H25-H28 Disorders of lens
0.000 0.280 0.720
K86.0 Alcohol-induced chronic pancreatitis
0.000 0.280 0.720
M10 Gout
0.000 0.280 0.720
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.280 0.720
C91.9 Lymphoid leukaemia, unspecified
0.000 0.281 0.719
H30 Chorioretinal inflammation
0.000 0.282 0.718
N05.7 Diffuse crescentic glomerulonephritis
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
K77 Liver disorders in diseases classified elsewhere
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
C21.2 Cloacogenic zone
0.000 0.283 0.717
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.000 0.283 0.717
L87 Transepidermal elimination disorders
0.000 0.283 0.717
L86 Keratoderma in diseases classified elsewhere
0.000 0.283 0.717
K75.2 Nonspecific reactive hepatitis
0.000 0.283 0.717
K75.1 Phlebitis of portal vein
0.000 0.283 0.717
K90.3 Pancreatic steatorrhoea
0.000 0.283 0.717
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.283 0.717
K90.1 Tropical sprue
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.716
M08 Juvenile arthritis
0.000 0.283 0.716
D64.4 Congenital dyserythropoietic anaemia
0.000 0.284 0.716
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.284 0.716
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.284 0.716
D64.0 Hereditary sideroblastic anaemia
0.000 0.284 0.716
M05.8 Other seropositive rheumatoid arthritis
0.000 0.284 0.716
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.284 0.716
M05.1 Rheumatoid lung disease
0.000 0.284 0.716
M05.0 Felty's syndrome
0.000 0.284 0.716
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.284 0.716
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.284 0.716
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.284 0.716
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.284 0.716
H31 Other disorders of choroid
0.000 0.284 0.716
D50.1 Sideropenic dysphagia
0.000 0.284 0.716
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.284 0.716
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.284 0.716
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.284 0.716
D07.6 Other and unspecified male genital organs
0.000 0.284 0.716
D07.3 Other and unspecified female genital organs
0.000 0.284 0.716
D07.0 Endometrium
0.000 0.284 0.716
L90.9 Atrophic disorder of skin, unspecified
0.000 0.284 0.716
L90.6 Striae atrophicae
0.000 0.284 0.716
L90.4 Acrodermatitis chronica atrophicans
0.000 0.284 0.716
L90.3 Atrophoderma of Pasini and Pierini
0.000 0.284 0.716
L90.2 Anetoderma of Jadassohn-Pellizzari
0.000 0.284 0.716
L90.1 Anetoderma of Schweninger-Buzzi
0.000 0.284 0.716
N07 Hereditary nephropathy, not elsewhere classified
0.000 0.284 0.716
N06 Isolated proteinuria with specified morphological lesion
0.000 0.284 0.716
N01 Rapidly progressive nephritic syndrome
0.000 0.284 0.716
N00 Acute nephritic syndrome
0.000 0.284 0.716
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.284 0.715
K86.1 Other chronic pancreatitis
0.000 0.285 0.715
G72.0 Drug-induced myopathy
0.000 0.285 0.715
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.285 0.715
E32 Diseases of thymus
0.000 0.285 0.715
E31 Polyglandular dysfunction
0.000 0.285 0.715
E30 Disorders of puberty, not elsewhere classified
0.000 0.285 0.715
D06.7 Other parts of cervix
0.000 0.286 0.714
D06.1 Exocervix
0.000 0.286 0.714
L92.2 Granuloma faciale [eosinophilic granuloma of skin]
0.000 0.287 0.713
L92.1 Necrobiosis lipoidica, not elsewhere classified
0.000 0.287 0.713
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.288 0.712
D01.3 Anus and anal canal
0.000 0.288 0.712
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.288 0.712
E27.5 Adrenomedullary hyperfunction
0.000 0.288 0.711
E27.0 Other adrenocortical overactivity
0.000 0.288 0.711
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.000 0.290 0.710
M48 Other spondylopathies
0.000 0.290 0.710
N08.8 Glomerular disorders in other diseases classified elsewhere
0.000 0.290 0.710
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.000 0.290 0.710
N08.1 Glomerular disorders in neoplastic diseases
0.000 0.290 0.710
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.000 0.290 0.710
D04.9 Skin, unspecified
0.000 0.290 0.710
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.291 0.709
D51.2 Transcobalamin II deficiency
0.000 0.291 0.709
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.291 0.709
E21.4 Other specified disorders of parathyroid gland
0.000 0.291 0.709
C91.0 Acute lymphoblastic leukaemia
0.000 0.291 0.709
G61.0 Guillain-Barre syndrome
0.000 0.291 0.709
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.291 0.709
N05.6 Dense deposit disease
0.000 0.291 0.708
N05.4 Diffuse endocapillary proliferative glomerulonephritis
0.000 0.291 0.708
N05.0 Minor glomerular abnormality
0.000 0.291 0.708
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens
0.000 0.292 0.708
K55.8 Other vascular disorders of intestine
0.000 0.293 0.707
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.293 0.707
E24.2 Drug-induced Cushing's syndrome
0.000 0.293 0.707
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.293 0.707
N44 Torsion of testis
0.000 0.294 0.706
N04.2 Diffuse membranous glomerulonephritis
0.000 0.296 0.704
E11.8 With unspecified complications
0.000 0.299 0.700
H34.2 Other retinal artery occlusions
0.000 0.303 0.697
K71 Toxic liver disease
0.000 0.304 0.696
H43.0 Vitreous prolapse
0.000 0.304 0.695
M45 Ankylosing spondylitis
0.000 0.305 0.695
N49.9 Inflammatory disorder of unspecified male genital organ
0.000 0.306 0.694
N49.0 Inflammatory disorders of seminal vesicle
0.000 0.306 0.694
C04.9 Floor of mouth, unspecified
0.000 0.306 0.694
D01.0 Colon
0.000 0.307 0.693
D53 Other nutritional anaemias
0.000 0.308 0.692
D04.7 Skin of lower limb, including hip
0.000 0.308 0.692
L40.4 Guttate psoriasis
0.000 0.310 0.690
L13.0 Dermatitis herpetiformis
0.000 0.310 0.690
E40-E46 Malnutrition
0.000 0.310 0.689
E20.9 Hypoparathyroidism, unspecified
0.000 0.312 0.688
C95 Leukaemia of unspecified cell type
0.000 0.313 0.687
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.000 0.313 0.686
D07.2 Vagina
0.000 0.315 0.685
H43.2 Crystalline deposits in vitreous body
0.000 0.316 0.684
M06.1 Adult-onset Still's disease
0.000 0.316 0.684
K82 Other diseases of gallbladder
0.000 0.316 0.684
H35 Other retinal disorders
0.000 0.316 0.684
C09.8 Overlapping lesion of tonsil
0.000 0.317 0.683
C09.1 Tonsillar pillar (anterior) (posterior)
0.000 0.317 0.683
C09.0 Tonsillar fossa
0.000 0.317 0.683
G64 Other disorders of peripheral nervous system
0.000 0.318 0.682
I77.6 Arteritis, unspecified
0.000 0.318 0.682
E07.1 Dyshormogenetic goitre
0.000 0.319 0.681
E07.0 Hypersecretion of calcitonin
0.000 0.319 0.681
C08 Malignant neoplasm of other and unspecified major salivary glands
0.000 0.319 0.681
K72.1 Chronic hepatic failure
0.000 0.320 0.680
H34.9 Retinal vascular occlusion, unspecified
0.000 0.320 0.680
G60.0 Hereditary motor and sensory neuropathy
0.000 0.321 0.679
L44 Other papulosquamous disorders
0.000 0.321 0.679
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.321 0.679
H34.0 Transient retinal artery occlusion
0.000 0.321 0.679
E03.1 Congenital hypothyroidism without goitre
0.000 0.321 0.679
E25 Adrenogenital disorders
0.000 0.325 0.675
E83 Disorders of mineral metabolism
0.675 0.325 0.000
N04.8 Other
0.000 0.326 0.674
N04.7 Diffuse crescentic glomerulonephritis
0.000 0.326 0.674
N04.6 Dense deposit disease
0.000 0.326 0.674
N04.5 Diffuse mesangiocapillary glomerulonephritis
0.000 0.326 0.674
N04.4 Diffuse endocapillary proliferative glomerulonephritis
0.000 0.326 0.674
N04.3 Diffuse mesangial proliferative glomerulonephritis
0.000 0.326 0.674
N04.0 Minor glomerular abnormality
0.000 0.326 0.674
G63.8 Polyneuropathy in other diseases classified elsewhere
0.000 0.326 0.674
G63.6 Polyneuropathy in other musculoskeletal disorders
0.000 0.326 0.674
G63.5 Polyneuropathy in systemic connective tissue disorders
0.000 0.326 0.674
G63.4 Polyneuropathy in nutritional deficiency
0.000 0.326 0.674
G63.3 Polyneuropathy in other endocrine and metabolic diseases
0.000 0.326 0.674
G63.1 Polyneuropathy in neoplastic disease
0.000 0.326 0.674
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere
0.000 0.326 0.674
J45.8 Mixed asthma
0.000 0.327 0.673
E13.3 With ophthalmic complications
0.000 0.327 0.673
I25.1 Atherosclerotic heart disease
0.000 0.328 0.672
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.330 0.670
M06.38 Rheumatoid nodule (Other)
0.000 0.330 0.670
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.330 0.670
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.330 0.670
M06.33 Rheumatoid nodule (Forearm)
0.000 0.330 0.670
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.330 0.670
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.330 0.670
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.332 0.668
I10 Essential (primary) hypertension
0.000 0.332 0.668
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.333 0.667
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.333 0.667
L40.3 Pustulosis palmaris et plantaris
0.000 0.333 0.667
L40.2 Acrodermatitis continua
0.000 0.333 0.667
M11 Other crystal arthropathies
0.000 0.335 0.664
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.336 0.664
C22.7 Other specified carcinomas of liver
0.000 0.336 0.664
C22.4 Other sarcomas of liver
0.000 0.336 0.664
C22.3 Angiosarcoma of liver
0.000 0.336 0.664
C22.2 Hepatoblastoma
0.000 0.336 0.664
C10.9 Oropharynx, unspecified
0.000 0.337 0.663
G00.9 Bacterial meningitis, unspecified
0.000 0.338 0.662
M49 Spondylopathies in diseases classified elsewhere
0.000 0.339 0.661
E06.5 Other chronic thyroiditis
0.000 0.339 0.661
J98.6 Disorders of diaphragm
0.000 0.339 0.661
G06 Intracranial and intraspinal abscess and granuloma
0.000 0.340 0.660

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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