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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9269819
log Bayes Factor = 255.668
Chromosome 6   position 32,549,782  (GRCh37) Explore rs9269819 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K51.9 Ulcerative colitis, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
K51 Ulcerative colitis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
Z93.2 Ileostomy status
1.000 0.000 0.000
E03 Other hypothyroidism
0.000 0.000 1.000
E14.9 Without complications
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
C44.3 Skin of other and unspecified parts of face
1.000 0.000 0.000
E10.4 With neurological complications
0.000 0.001 0.999
J45 Asthma
0.000 0.001 0.999
J40-J47 Chronic lower respiratory diseases
0.000 0.001 0.999
K51.8 Other ulcerative colitis
0.999 0.001 0.000
K51.4 Pseudopolyposis of colon
0.999 0.001 0.000
K90 Intestinal malabsorption
0.000 0.002 0.998
# Top node
0.000 0.002 0.998
Chapter X Diseases of the respiratory system
0.000 0.003 0.997
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.003 0.997
Chapter XI Diseases of the digestive system
0.000 0.003 0.997
K90-K93 Other diseases of the digestive system
0.000 0.004 0.996
C44 Other malignant neoplasms of skin
0.995 0.005 0.000
E14.3 With ophthalmic complications
0.000 0.006 0.994
K51.3 Ulcerative (chronic) rectosigmoiditis
0.993 0.007 0.000
K70-K77 Diseases of liver
0.000 0.008 0.992
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.009 0.991
E11.1 With ketoacidosis
0.000 0.011 0.989
H36 Retinal disorders in diseases classified elsewhere
0.000 0.013 0.987
K86 Other diseases of pancreas
0.000 0.016 0.984
D64.9 Anaemia, unspecified
0.000 0.017 0.983
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.017 0.983
D60-D64 Aplastic and other anaemias
0.000 0.017 0.983
D64 Other anaemias
0.000 0.018 0.982
L90.0 Lichen sclerosus et atrophicus
0.000 0.019 0.981
E11.3 With ophthalmic complications
0.000 0.020 0.980
E05.9 Thyrotoxicosis, unspecified
0.000 0.020 0.980
E10.5 With peripheral circulatory complications
0.000 0.021 0.979
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.022 0.978
H30-H36 Disorders of choroid and retina
0.000 0.023 0.977
G35-G37 Demyelinating diseases of the central nervous system
0.975 0.024 0.001
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.025 0.975
L90 Atrophic disorders of skin
0.000 0.025 0.975
K51.2 Ulcerative (chronic) proctitis
0.975 0.025 0.000
K75 Other inflammatory liver diseases
0.000 0.026 0.974
K75.4 Autoimmune hepatitis
0.000 0.029 0.971
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.030 0.970
G37 Other demyelinating diseases of central nervous system
0.970 0.030 0.000
K74 Fibrosis and cirrhosis of liver
0.000 0.030 0.970
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.033 0.967
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.033 0.967
G37.9 Demyelinating disease of central nervous system, unspecified
0.965 0.035 0.000
J43 Emphysema
0.000 0.039 0.961
Chapter VII Diseases of the eye and adnexa
0.000 0.042 0.958
E10.8 With unspecified complications
0.000 0.044 0.956
L40-L45 Papulosquamous disorders
0.000 0.044 0.956
K86.1 Other chronic pancreatitis
0.000 0.046 0.954
K86.0 Alcohol-induced chronic pancreatitis
0.000 0.047 0.953
E11.2 With renal complications
0.000 0.047 0.953
L92 Granulomatous disorders of skin and subcutaneous tissue
0.000 0.050 0.950
L40 Psoriasis
0.000 0.052 0.948
J86 Pyothorax
0.000 0.053 0.947
L40.9 Psoriasis, unspecified
0.000 0.060 0.940
H34 Retinal vascular occlusions
0.000 0.063 0.937
J43.9 Emphysema, unspecified
0.000 0.064 0.936
J95-J99 Other diseases of the respiratory system
0.000 0.066 0.934
C44.7 Skin of lower limb, including hip
0.934 0.066 0.000
K90.9 Intestinal malabsorption, unspecified
0.000 0.068 0.932
C44.1 Skin of eyelid, including canthus
0.932 0.068 0.000
K51.5 Mucosal proctocolitis
0.929 0.071 0.000
J46 Status asthmaticus
0.000 0.073 0.927
D80-D89 Certain disorders involving the immune mechanism
0.000 0.074 0.926
E11.5 With peripheral circulatory complications
0.000 0.077 0.923
C44.9 Malignant neoplasm of skin, unspecified
0.923 0.077 0.000
L80 Vitiligo
0.000 0.078 0.922
D50-D53 Nutritional anaemias
0.000 0.080 0.920
L92.0 Granuloma annulare
0.000 0.080 0.920
E10.0 With coma
0.000 0.082 0.918
E03.8 Other specified hypothyroidism
0.000 0.085 0.915
K86.3 Pseudocyst of pancreas
0.000 0.086 0.914
H43-H45 Disorders of vitreous body and globe
0.000 0.087 0.913
E10.2 With renal complications
0.000 0.092 0.908
D86 Sarcoidosis
0.000 0.093 0.907
D50 Iron deficiency anaemia
0.000 0.094 0.906
E11.6 With other specified complications
0.000 0.096 0.904
D50.9 Iron deficiency anaemia, unspecified
0.000 0.097 0.903
J98 Other respiratory disorders
0.000 0.098 0.902
H43 Disorders of vitreous body
0.000 0.102 0.898
K74.3 Primary biliary cirrhosis
0.000 0.105 0.895
H34.8 Other retinal vascular occlusions
0.000 0.107 0.893
J86.9 Pyothorax without fistula
0.000 0.111 0.889
K82 Other diseases of gallbladder
0.000 0.116 0.884
K72 Hepatic failure, not elsewhere classified
0.000 0.117 0.883
J33 Nasal polyp
0.000 0.118 0.882
J33.9 Nasal polyp, unspecified
0.000 0.120 0.880
D86.9 Sarcoidosis, unspecified
0.000 0.122 0.878
E13 Other specified diabetes mellitus
0.000 0.130 0.870
E10.6 With other specified complications
0.000 0.132 0.868
J86.0 Pyothorax with fistula
0.000 0.132 0.868
E06 Thyroiditis
0.000 0.134 0.866
Chapter VIII Diseases of the ear and mastoid process
0.000 0.134 0.866
K86.2 Cyst of pancreas
0.000 0.134 0.866
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.138 0.862
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.000 0.139 0.861
K74.5 Biliary cirrhosis, unspecified
0.000 0.140 0.860
H60-H62 Diseases of external ear
0.000 0.140 0.860
K74.6 Other and unspecified cirrhosis of liver
0.000 0.141 0.859
J44 Other chronic obstructive pulmonary disease
0.000 0.141 0.859
H43.3 Other vitreous opacities
0.000 0.143 0.857
E20-E35 Disorders of other endocrine glands
0.000 0.145 0.855
K86.8 Other specified diseases of pancreas
0.000 0.146 0.854
E14.8 With unspecified complications
0.000 0.146 0.854
C44.5 Skin of trunk
0.854 0.146 0.000
E83 Disorders of mineral metabolism
0.853 0.147 0.000
E07 Other disorders of thyroid
0.000 0.149 0.851
J33.8 Other polyp of sinus
0.000 0.149 0.851
H61 Other disorders of external ear
0.000 0.150 0.850
J33.0 Polyp of nasal cavity
0.000 0.155 0.845
J98.0 Diseases of bronchus, not elsewhere classified
0.000 0.158 0.842
H61.0 Perichondritis of external ear
0.000 0.158 0.842
E16.1 Other hypoglycaemia
0.000 0.160 0.840
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.166 0.834
E83.3 Disorders of phosphorus metabolism
0.834 0.166 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.167 0.833
J98.4 Other disorders of lung
0.000 0.177 0.823
J30-J39 Other diseases of upper respiratory tract
0.000 0.177 0.823
K73 Chronic hepatitis, not elsewhere classified
0.000 0.181 0.819
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.185 0.815
K82.8 Other specified diseases of gallbladder
0.000 0.187 0.813
H43.8 Other disorders of vitreous body
0.000 0.193 0.807
K72.0 Acute and subacute hepatic failure
0.000 0.195 0.805
E40-E46 Malnutrition
0.000 0.197 0.803
E14.6 With other specified complications
0.000 0.199 0.801
L10-L14 Bullous disorders
0.000 0.200 0.800
H35 Other retinal disorders
0.000 0.201 0.799
C44.0 Skin of lip
0.793 0.207 0.000
D86.8 Sarcoidosis of other and combined sites
0.000 0.207 0.793
E65-E68 Obesity and other hyperalimentation
0.000 0.217 0.783
E24 Cushing's syndrome
0.000 0.217 0.783
E13.9 Without complications
0.000 0.217 0.783
L40.0 Psoriasis vulgaris
0.000 0.225 0.775
K82.9 Disease of gallbladder, unspecified
0.000 0.226 0.774
C44.6 Skin of upper limb, including shoulder
0.772 0.228 0.000
E06.3 Autoimmune thyroiditis
0.000 0.237 0.763
K74.0 Hepatic fibrosis
0.000 0.238 0.762
E07.9 Disorder of thyroid, unspecified
0.000 0.239 0.761
E14.2 Withrenal complications
0.000 0.241 0.759
E14.5 With peripheral circulatory complications
0.000 0.242 0.758
E14.4 With neurological complications
0.000 0.245 0.755
J98.6 Disorders of diaphragm
0.000 0.245 0.755
H43.1 Vitreous haemorrhage
0.000 0.245 0.755
J42 Unspecified chronic bronchitis
0.000 0.247 0.753
H53-H54 Visual disturbances and blindness
0.000 0.251 0.749
J98.9 Respiratory disorder, unspecified
0.000 0.251 0.749
J85 Abscess of lung and mediastinum
0.000 0.252 0.748
L40.8 Other psoriasis
0.000 0.252 0.748
E27 Other disorders of adrenal gland
0.000 0.254 0.746
J45.0 Predominantly allergic asthma
0.000 0.254 0.746
L40.1 Generalised pustular psoriasis
0.000 0.255 0.745
H34.2 Other retinal artery occlusions
0.000 0.255 0.745
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.000 0.256 0.744
K51.0 Ulcerative (chronic) enterocolitis
0.743 0.257 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.740 0.260 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.260 0.740
C44.4 Skin of scalp and neck
0.739 0.261 0.000
H60 Otitis externa
0.000 0.263 0.737
H35.2 Other proliferative retinopathy
0.000 0.263 0.737
J43.2 Centrilobular emphysema
0.000 0.272 0.728
G37.8 Other specified demyelinating diseases of central nervous system
0.726 0.274 0.000
L94 Other localised connective tissue disorders
0.000 0.275 0.725
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.275 0.725
Chapter XIV Diseases of the genitourinary system
0.000 0.277 0.723
D80 Immunodeficiency with predominantly antibody defects
0.000 0.278 0.722
N00-N08 Glomerular diseases
0.000 0.280 0.720
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
K90.3 Pancreatic steatorrhoea
0.000 0.284 0.716
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.284 0.716
K90.1 Tropical sprue
0.000 0.284 0.716
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.284 0.716
E05.5 Thyroid crisis or storm
0.000 0.285 0.715
E05.4 Thyrotoxicosis factitia
0.000 0.285 0.715
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.285 0.715
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.285 0.715
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.286 0.714
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.286 0.714
C44.8 Overlapping lesion of skin
0.713 0.286 0.000
G36 Other acute disseminated demyelination
0.713 0.287 0.000
J45.1 Nonallergic asthma
0.000 0.287 0.713
K77 Liver disorders in diseases classified elsewhere
0.000 0.288 0.711
E21.0 Primary hyperparathyroidism
0.000 0.290 0.710
N08 Glomerular disorders in diseases classified elsewhere
0.000 0.290 0.710
N08.3 Glomerular disorders in diabetes mellitus
0.000 0.290 0.710
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.293 0.707
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.293 0.707
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.000 0.295 0.705
D86.1 Sarcoidosis of lymph nodes
0.000 0.295 0.705
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.295 0.704
D64.4 Congenital dyserythropoietic anaemia
0.000 0.296 0.704
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.296 0.704
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.296 0.704
D64.0 Hereditary sideroblastic anaemia
0.000 0.296 0.704
N18 Chronic renal failure
0.000 0.297 0.703
H61.8 Other specified disorders of external ear
0.000 0.299 0.701
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.299 0.701
H34.9 Retinal vascular occlusion, unspecified
0.000 0.299 0.700
E27.1 Primary adrenocortical insufficiency
0.000 0.300 0.700
N17-N19 Renal failure
0.000 0.300 0.700
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.000 0.301 0.699
L87 Transepidermal elimination disorders
0.000 0.301 0.699
L86 Keratoderma in diseases classified elsewhere
0.000 0.301 0.699
L90.9 Atrophic disorder of skin, unspecified
0.000 0.301 0.699
L90.6 Striae atrophicae
0.000 0.301 0.699
L90.4 Acrodermatitis chronica atrophicans
0.000 0.301 0.699
L90.3 Atrophoderma of Pasini and Pierini
0.000 0.301 0.699
L90.2 Anetoderma of Jadassohn-Pellizzari
0.000 0.301 0.699
L90.1 Anetoderma of Schweninger-Buzzi
0.000 0.301 0.699
N18.9 Chronic renal failure, unspecified
0.000 0.301 0.699
K75.2 Nonspecific reactive hepatitis
0.000 0.301 0.699
K75.1 Phlebitis of portal vein
0.000 0.301 0.699
J98.8 Other specified respiratory disorders
0.000 0.301 0.699
L13 Other bullous disorders
0.000 0.303 0.697
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.304 0.696
G37.5 Concentric sclerosis [Balo]
0.696 0.304 0.000
G37.4 Subacute necrotising myelitis
0.696 0.304 0.000
G37.2 Central pontine myelinolysis
0.696 0.304 0.000
G37.1 Central demyelination of corpus callosum
0.696 0.304 0.000
G37.0 Diffuse sclerosis
0.696 0.304 0.000
L43 Lichen planus
0.000 0.305 0.695
K74.4 Secondary biliary cirrhosis
0.000 0.305 0.695
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.305 0.695
E83.9 Disorder of mineral metabolism, unspecified
0.693 0.307 0.000
E24.9 Cushing's syndrome, unspecified
0.000 0.308 0.692
H54 Blindness and low vision
0.000 0.309 0.691
E66 Obesity
0.000 0.309 0.691
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.310 0.690
Q60-Q64 Congenital malformations of the urinary system
0.000 0.310 0.690
J43.1 Panlobular emphysema
0.000 0.311 0.689
J43.0 MacLeod's syndrome
0.000 0.311 0.689
D55-D59 Haemolytic anaemias
0.000 0.312 0.688
N40-N51 Diseases of male genital organs
0.000 0.313 0.687
L44 Other papulosquamous disorders
0.000 0.314 0.685
L41 Parapsoriasis
0.000 0.314 0.685
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.314 0.685
N48 Other disorders of penis
0.000 0.315 0.685
H61.1 Non-infective disorders of pinna
0.000 0.317 0.683
L92.2 Granuloma faciale [eosinophilic granuloma of skin]
0.000 0.319 0.681
L92.1 Necrobiosis lipoidica, not elsewhere classified
0.000 0.319 0.681
K82.3 Fistula of gallbladder
0.000 0.319 0.681
L40.4 Guttate psoriasis
0.000 0.321 0.679
L40.3 Pustulosis palmaris et plantaris
0.000 0.321 0.679
L40.2 Acrodermatitis continua
0.000 0.321 0.679
N05 Unspecified nephritic syndrome
0.000 0.321 0.679
Q80-Q89 Other congenital malformations
0.000 0.321 0.679
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.000 0.321 0.679
K71 Toxic liver disease
0.000 0.323 0.677
H30 Chorioretinal inflammation
0.000 0.324 0.676
J98.2 Interstitial emphysema
0.000 0.325 0.675
H34.0 Transient retinal artery occlusion
0.000 0.328 0.672
E21.3 Hyperparathyroidism, unspecified
0.000 0.328 0.672
H34.1 Central retinal artery occlusion
0.000 0.329 0.671
J96 Respiratory failure, not elsewhere classified
0.000 0.330 0.670
K82.2 Perforation of gallbladder
0.000 0.330 0.670
N47 Redundant prepuce, phimosis and paraphimosis
0.000 0.331 0.669
D53 Other nutritional anaemias
0.000 0.331 0.669
N48.6 Balanitis xerotica obliterans
0.000 0.333 0.667
E66.9 Obesity, unspecified
0.000 0.333 0.667
E11.0 With coma
0.000 0.334 0.666
J41 Simple and mucopurulent chronic bronchitis
0.000 0.334 0.666
D82 Immunodeficiency associated with other major defects
0.000 0.336 0.664
D81 Combined immunodeficiencies
0.000 0.336 0.664
E46 Unspecified protein-energy malnutrition
0.000 0.337 0.663
H54.7 Unspecified visual loss
0.000 0.338 0.662
D83 Common variable immunodeficiency
0.000 0.338 0.662
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.339 0.661
H35.0 Background retinopathy and retinal vascular changes
0.000 0.341 0.659
E24.0 Pituitary-dependent Cushing's disease
0.000 0.341 0.659
Q61 Cystic kidney disease
0.000 0.342 0.658
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.344 0.656
H61.3 Acquired stenosis of external ear canal
0.000 0.344 0.656
J33.1 Polypoid sinus degeneration
0.000 0.345 0.655
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.345 0.655
E03.1 Congenital hypothyroidism without goitre
0.000 0.347 0.653
H60.9 Otitis externa, unspecified
0.000 0.347 0.653
D86.3 Sarcoidosis of skin
0.000 0.350 0.650
N48.0 Leukoplakia of penis
0.000 0.350 0.650
D50.1 Sideropenic dysphagia
0.000 0.351 0.649
J45.8 Mixed asthma
0.000 0.352 0.648
H43.2 Crystalline deposits in vitreous body
0.000 0.352 0.648
N04 Nephrotic syndrome
0.000 0.353 0.647
J98.3 Compensatory emphysema
0.000 0.353 0.647
J85.2 Abscess of lung without pneumonia
0.000 0.355 0.645
H43.0 Vitreous prolapse
0.000 0.356 0.644
E11.8 With unspecified complications
0.000 0.359 0.641
K72.9 Hepatic failure, unspecified
0.000 0.361 0.639
E06.9 Thyroiditis, unspecified
0.000 0.362 0.638
E05.8 Other thyrotoxicosis
0.000 0.366 0.634
K82.0 Obstruction of gallbladder
0.000 0.366 0.634
K90.8 Other intestinal malabsorption
0.000 0.368 0.632
K51.1 Ulcerative (chronic) ileocolitis
0.631 0.369 0.000
J37 Chronic laryngitis and laryngotracheitis
0.000 0.369 0.631
J95.0 Tracheostomy malfunction
0.000 0.370 0.630
N18.2 Chronic kidney disease, stage 2
0.000 0.373 0.627
K72.1 Chronic hepatic failure
0.000 0.374 0.626
E13.8 With unspecified complications
0.000 0.376 0.624
E13.7 With multiple complications
0.000 0.376 0.624
E13.6 With other specified complications
0.000 0.376 0.624
E13.5 With peripheral circulatory complications
0.000 0.376 0.624
E13.4 With neurological complications
0.000 0.376 0.624
E13.2 With renal complications
0.000 0.376 0.624
E13.1 With ketoacidosis
0.000 0.376 0.624
E13.0 With coma
0.000 0.376 0.624
L13.0 Dermatitis herpetiformis
0.000 0.376 0.623
Q85 Phakomatoses, not elsewhere classified
0.000 0.377 0.623
E29 Testicular dysfunction
0.000 0.378 0.622
Q61.2 Polycystic kidney, adult type
0.000 0.378 0.622
D64.3 Other sideroblastic anaemias
0.000 0.379 0.621
E06.5 Other chronic thyroiditis
0.000 0.379 0.621
E06.4 Drug-induced thyroiditis
0.000 0.379 0.621
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.379 0.621
E06.1 Subacute thyroiditis
0.000 0.379 0.621
E06.0 Acute thyroiditis
0.000 0.379 0.621
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.379 0.621
C44.2 Skin of ear and external auricular canal
0.619 0.381 0.000
N48.1 Balanoposthitis
0.000 0.382 0.618
H62 Disorders of external ear in diseases classified elsewhere
0.000 0.383 0.616
J43.8 Other emphysema
0.000 0.383 0.616
H35.8 Other specified retinal disorders
0.000 0.384 0.616
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.385 0.615
H35.4 Peripheral retinal degeneration
0.000 0.386 0.614
H35.5 Hereditary retinal dystrophy
0.000 0.386 0.614
D62 Acute posthaemorrhagic anaemia
0.000 0.387 0.613
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.387 0.613
E32 Diseases of thymus
0.000 0.387 0.613
E31 Polyglandular dysfunction
0.000 0.387 0.613
E30 Disorders of puberty, not elsewhere classified
0.000 0.387 0.613
E83.8 Other disorders of mineral metabolism
0.611 0.388 0.000
E83.2 Disorders of zinc metabolism
0.611 0.388 0.000
E83.0 Disorders of copper metabolism
0.611 0.388 0.000
K75.8 Other specified inflammatory liver diseases
0.000 0.389 0.611
L95 Vasculitis limited to skin, not elsewhere classified
0.000 0.389 0.611
E07.1 Dyshormogenetic goitre
0.000 0.390 0.610
E07.0 Hypersecretion of calcitonin
0.000 0.390 0.610
N05.2 Diffuse membranous glomerulonephritis
0.000 0.390 0.610
H35.6 Retinal haemorrhage
0.000 0.391 0.609
E13.3 With ophthalmic complications
0.000 0.392 0.608
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.394 0.606
Q61.3 Polycystic kidney, unspecified
0.000 0.398 0.602
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.404 0.596
H60.3 Other infective otitis externa
0.000 0.404 0.596
N04.9 Unspecified
0.000 0.404 0.596
K73.9 Chronic hepatitis, unspecified
0.000 0.406 0.594
L90.8 Other atrophic disorders of skin
0.000 0.409 0.590
N18.4 Chronic kidney disease, stage 4
0.000 0.410 0.590
E11.4 With neurological complications
0.000 0.411 0.589
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.000 0.411 0.589
N42 Other disorders of prostate
0.000 0.412 0.588
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.413 0.587
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.413 0.587
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.413 0.587
E21.4 Other specified disorders of parathyroid gland
0.000 0.416 0.584
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.000 0.416 0.584
E20 Hypoparathyroidism
0.000 0.417 0.582
D50.8 Other iron deficiency anaemias
0.000 0.418 0.582
Q89 Other congenital malformations, not elsewhere classified
0.000 0.420 0.580
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.424 0.576
E45 Retarded development following protein-energy malnutrition
0.000 0.424 0.576
E43 Unspecified severe protein-energy malnutrition
0.000 0.424 0.576
E42 Marasmic kwashiorkor
0.000 0.424 0.576
E41 Nutritional marasmus
0.000 0.424 0.576
E40 Kwashiorkor
0.000 0.424 0.576
H61.9 Disorder of external ear, unspecified
0.000 0.425 0.575
H54.0 Blindness, both eyes
0.000 0.425 0.575
L11 Other acantholytic disorders
0.000 0.425 0.575
L10 Pemphigus
0.000 0.426 0.573
L14 Bullous disorders in diseases classified elsewhere
0.000 0.426 0.573
K50-K52 Noninfective enteritis and colitis
0.147 0.427 0.426
H35.1 Retinopathy of prematurity
0.000 0.427 0.573
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.000 0.428 0.572
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.000 0.429 0.571
E07.8 Other specified disorders of thyroid
0.000 0.431 0.568
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.432 0.568
H43.9 Disorder of vitreous body, unspecified
0.000 0.433 0.567
Q85.9 Phakomatosis, unspecified
0.000 0.436 0.564
E67 Other hyperalimentation
0.000 0.438 0.562
E68 Sequelae of hyperalimentation
0.000 0.438 0.562
E24.8 Other Cushing's syndrome
0.000 0.438 0.562
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.438 0.562
E24.3 Ectopic ACTH syndrome
0.000 0.438 0.562
E24.2 Drug-induced Cushing's syndrome
0.000 0.438 0.562
E24.1 Nelson's syndrome
0.000 0.438 0.562
K75.9 Inflammatory liver disease, unspecified
0.000 0.439 0.561
N05.9 Unspecified
0.000 0.439 0.561
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.000 0.439 0.561
L94.2 Calcinosis cutis
0.000 0.439 0.561
L94.9 Localised connective tissue disorder, unspecified
0.000 0.440 0.560
L84 Corns and callosities
0.000 0.441 0.558
H60.8 Other otitis externa
0.000 0.442 0.558
N05.1 Focal and segmental glomerular lesions
0.000 0.442 0.558
D86.0 Sarcoidosis of lung
0.000 0.446 0.554
J85.0 Gangrene and necrosis of lung
0.000 0.448 0.552
D58 Other hereditary haemolytic anaemias
0.000 0.448 0.552
H80-H83 Diseases of inner ear
0.000 0.449 0.551
K82.1 Hydrops of gallbladder
0.000 0.452 0.548
D80.1 Nonfamilial hypogammaglobulinaemia
0.000 0.456 0.544
J95.9 Postprocedural respiratory disorder, unspecified
0.000 0.456 0.544
E21.2 Other hyperparathyroidism
0.000 0.457 0.543
H60.5 Acute otitis externa, non-infective
0.000 0.458 0.542
H60.4 Cholesteatoma of external ear
0.000 0.459 0.541
H54.2 Low vision, both eyes
0.000 0.460 0.540
Q38-Q45 Other congenital malformations of the digestive system
0.000 0.460 0.540
L91 Hypertrophic disorders of skin
0.000 0.461 0.539
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.000 0.463 0.537
J85.3 Abscess of mediastinum
0.000 0.464 0.536
E27.5 Adrenomedullary hyperfunction
0.000 0.465 0.535
E27.0 Other adrenocortical overactivity
0.000 0.465 0.535
E28 Ovarian dysfunction
0.000 0.466 0.534
Q83 Congenital malformations of breast
0.000 0.468 0.532
N48.9 Disorder of penis, unspecified
0.000 0.471 0.529
H60.2 Malignant otitis externa
0.000 0.471 0.528
E25 Adrenogenital disorders
0.000 0.472 0.528
Q00-Q07 Congenital malformations of the nervous system
0.000 0.472 0.527
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.000 0.473 0.526
Q61.0 Congenital single renal cyst
0.000 0.475 0.525
G36.0 Neuromyelitis optica [Devic]
0.525 0.475 0.000
N25-N29 Other disorders of kidney and ureter
0.000 0.475 0.525
N49.2 Inflammatory disorders of scrotum
0.000 0.476 0.524
N05.8 Other
0.000 0.476 0.524
E26 Hyperaldosteronism
0.000 0.477 0.523
H54.1 Blindness, one eye, low vision, other eye
0.000 0.478 0.522
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.479 0.521
L94.6 Ainhum
0.000 0.480 0.520
L94.5 Poikiloderma vasculare atrophicans
0.000 0.480 0.520
L94.4 Gottron's papules
0.000 0.480 0.520
L94.3 Sclerodactyly
0.000 0.480 0.520
L94.1 Linear scleroderma
0.000 0.480 0.520
N18.0 End-stage renal disease
0.000 0.480 0.520
N42.2 Atrophy of prostate
0.000 0.481 0.519
N18.1 Chronic kidney disease, stage 1
0.000 0.482 0.518
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.000 0.482 0.518
D80.8 Other immunodeficiencies with predominantly antibody defects
0.000 0.482 0.518
D80.7 Transient hypogammaglobulinaemia of infancy
0.000 0.482 0.518
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.000 0.482 0.518
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.000 0.482 0.518
D80.0 Hereditary hypogammaglobulinaemia
0.000 0.482 0.518
J98.5 Diseases of mediastinum, not elsewhere classified
0.000 0.483 0.517
L12 Pemphigoid
0.000 0.483 0.517
N07 Hereditary nephropathy, not elsewhere classified
0.000 0.484 0.516
N06 Isolated proteinuria with specified morphological lesion
0.000 0.484 0.516
N01 Rapidly progressive nephritic syndrome
0.000 0.484 0.516
N00 Acute nephritic syndrome
0.000 0.484 0.516
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
P90-P96 Other disorders originating in the perinatal period
0.000 0.487 0.513
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn
0.000 0.487 0.513

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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