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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1265758
log Bayes Factor = 194.604
Chromosome 6   position 32,323,529  (GRCh37) Explore rs1265758 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
L40 Psoriasis
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E14.9 Without complications
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
E14.3 With ophthalmic complications
0.000 0.000 1.000
J33 Nasal polyp
0.000 0.000 1.000
J33.0 Polyp of nasal cavity
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.001 0.999
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.001 0.999
H36 Retinal disorders in diseases classified elsewhere
0.000 0.001 0.999
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.001 0.999
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.001 0.999
H30-H36 Disorders of choroid and retina
0.000 0.002 0.998
L40.5 Arthropathic psoriasis
0.000 0.002 0.998
M35.3 Polymyalgia rheumatica
0.000 0.002 0.998
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.002 0.998
M07 Psoriatic and enteropathic arthropathies
0.000 0.002 0.998
M07.3 Other psoriatic arthropathies
0.000 0.003 0.997
E10.4 With neurological complications
0.000 0.004 0.996
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.004 0.996
G35-G37 Demyelinating diseases of the central nervous system
0.996 0.004 0.000
# Top node
0.000 0.005 0.995
G37 Other demyelinating diseases of central nervous system
0.995 0.005 0.000
J33.9 Nasal polyp, unspecified
0.000 0.005 0.995
G37.9 Demyelinating disease of central nervous system, unspecified
0.994 0.006 0.000
M35 Other systemic involvement of connective tissue
0.000 0.006 0.994
J45 Asthma
0.000 0.007 0.993
Chapter X Diseases of the respiratory system
0.000 0.008 0.992
Chapter VII Diseases of the eye and adnexa
0.000 0.008 0.992
J40-J47 Chronic lower respiratory diseases
0.000 0.008 0.992
M20-M25 Other joint disorders
0.000 0.008 0.992
L40-L45 Papulosquamous disorders
0.000 0.010 0.990
E11.1 With ketoacidosis
0.000 0.011 0.989
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.011 0.989
E10.2 With renal complications
0.000 0.013 0.987
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.021 0.979
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.025 0.975
M06.3 Rheumatoid nodule
0.000 0.026 0.974
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.026 0.974
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.027 0.973
J43 Emphysema
0.000 0.030 0.970
J33.8 Other polyp of sinus
0.000 0.032 0.968
E10.5 With peripheral circulatory complications
0.000 0.035 0.965
J30-J39 Other diseases of upper respiratory tract
0.000 0.039 0.961
E10.0 With coma
0.000 0.042 0.958
L40.0 Psoriasis vulgaris
0.000 0.048 0.952
E11.3 With ophthalmic complications
0.000 0.054 0.946
E70-E90 Metabolic disorders
0.000 0.057 0.943
M06.4 Inflammatory polyarthropathy
0.000 0.062 0.938
H33 Retinal detachments and breaks
0.000 0.066 0.934
M31 Other necrotising vasculopathies
0.000 0.075 0.924
E50-E64 Other nutritional deficiencies
0.000 0.076 0.924
J43.9 Emphysema, unspecified
0.000 0.076 0.924
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.079 0.921
H33.3 Retinal breaks without detachment
0.000 0.082 0.918
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.082 0.918
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.088 0.912
E10.8 With unspecified complications
0.000 0.090 0.910
J95-J99 Other diseases of the respiratory system
0.000 0.091 0.909
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.093 0.907
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.096 0.904
H53-H54 Visual disturbances and blindness
0.000 0.100 0.900
M35.1 Other overlap syndromes
0.000 0.103 0.897
E53 Deficiency of other B group vitamins
0.000 0.105 0.895
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.111 0.889
E10.6 With other specified complications
0.000 0.116 0.884
E53.8 Deficiency of other specified B group vitamins
0.000 0.118 0.882
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.119 0.881
E06 Thyroiditis
0.000 0.119 0.881
E11.2 With renal complications
0.000 0.120 0.880
H33.4 Traction detachment of retina
0.000 0.120 0.880
J95.0 Tracheostomy malfunction
0.000 0.124 0.876
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.125 0.875
H54 Blindness and low vision
0.000 0.127 0.873
M65-M68 Disorders of synovium and tendon
0.000 0.127 0.873
L80 Vitiligo
0.000 0.130 0.870
H34 Retinal vascular occlusions
0.000 0.135 0.865
M31.6 Other giant cell arteritis
0.000 0.136 0.864
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.137 0.863
E03.8 Other specified hypothyroidism
0.000 0.139 0.861
E86 Volume depletion
0.000 0.139 0.861
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.142 0.858
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.143 0.856
E11.8 With unspecified complications
0.000 0.144 0.856
E78.2 Mixed hyperlipidaemia
0.000 0.146 0.854
E88 Other metabolic disorders
0.000 0.146 0.854
E14.6 With other specified complications
0.000 0.152 0.848
H35 Other retinal disorders
0.000 0.155 0.845
E83.1 Disorders of iron metabolism
0.845 0.155 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.158 0.842
G37.8 Other specified demyelinating diseases of central nervous system
0.842 0.158 0.000
E89.0 Postprocedural hypothyroidism
0.000 0.160 0.840
E14.1 With ketoacidosis
0.000 0.162 0.838
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.163 0.837
J86 Pyothorax
0.000 0.164 0.836
L40.1 Generalised pustular psoriasis
0.000 0.166 0.834
E14.8 With unspecified complications
0.000 0.166 0.834
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.167 0.833
E78.4 Other hyperlipidaemia
0.000 0.167 0.833
L40.8 Other psoriasis
0.000 0.168 0.832
J43.2 Centrilobular emphysema
0.000 0.168 0.832
E16.1 Other hypoglycaemia
0.000 0.174 0.826
M06.34 Rheumatoid nodule (Hand)
0.000 0.175 0.825
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.180 0.820
L92 Granulomatous disorders of skin and subcutaneous tissue
0.000 0.180 0.820
M12 Other specific arthropathies
0.000 0.182 0.818
M34 Systemic sclerosis
0.000 0.186 0.814
M24 Other specific joint derangements
0.000 0.187 0.813
H35.4 Peripheral retinal degeneration
0.000 0.190 0.810
L90 Atrophic disorders of skin
0.000 0.194 0.806
M45-M49 Spondylopathies
0.000 0.195 0.805
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.195 0.805
M30 Polyarteritis nodosa and related conditions
0.000 0.197 0.803
H54.7 Unspecified visual loss
0.000 0.197 0.803
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.198 0.802
M80-M85 Disorders of bone density and structure
0.000 0.200 0.800
H35.8 Other specified retinal disorders
0.000 0.202 0.798
H54.0 Blindness, both eyes
0.000 0.203 0.797
E14.2 Withrenal complications
0.000 0.208 0.792
E83 Disorders of mineral metabolism
0.763 0.209 0.028
K90 Intestinal malabsorption
0.000 0.209 0.791
L10-L14 Bullous disorders
0.000 0.209 0.791
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.210 0.790
J46 Status asthmaticus
0.000 0.215 0.785
J43.8 Other emphysema
0.000 0.218 0.782
D60-D64 Aplastic and other anaemias
0.000 0.218 0.782
D64.9 Anaemia, unspecified
0.000 0.219 0.781
M65 Synovitis and tenosynovitis
0.000 0.221 0.779
D64 Other anaemias
0.000 0.221 0.779
L90.0 Lichen sclerosus et atrophicus
0.000 0.223 0.777
M86-M90 Other osteopathies
0.000 0.223 0.777
L40.3 Pustulosis palmaris et plantaris
0.000 0.225 0.775
M80 Osteoporosis with pathological fracture
0.000 0.226 0.774
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.230 0.770
M45 Ankylosing spondylitis
0.000 0.230 0.770
E78.6 Lipoprotein deficiency
0.000 0.231 0.769
G36 Other acute disseminated demyelination
0.768 0.232 0.000
E06.3 Autoimmune thyroiditis
0.000 0.234 0.766
M15-M19 Arthrosis
0.000 0.235 0.765
M24.1 Other articular cartilage disorders
0.000 0.235 0.765
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.764 0.236 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.000 0.236 0.764
J39 Other diseases of upper respiratory tract
0.000 0.237 0.763
J33.1 Polypoid sinus degeneration
0.000 0.238 0.762
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.000 0.240 0.760
M18 Arthrosis of first carpometacarpal joint
0.000 0.242 0.758
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.243 0.757
M35.7 Hypermobility syndrome
0.000 0.245 0.755
J86.0 Pyothorax with fistula
0.000 0.245 0.755
M91-M94 Chondropathies
0.000 0.252 0.748
M18.1 Other primary arthrosis of first carpometacarpal joint
0.000 0.253 0.747
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.253 0.747
L94 Other localised connective tissue disorders
0.000 0.255 0.745
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.256 0.744
D50-D53 Nutritional anaemias
0.000 0.256 0.744
M24.16 Other articular cartilage disorders (Lower leg)
0.000 0.261 0.739
M35.2 Behcet's disease
0.000 0.262 0.738
J86.9 Pyothorax without fistula
0.000 0.274 0.726
L84 Corns and callosities
0.000 0.274 0.726
H54.2 Low vision, both eyes
0.000 0.275 0.725
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.277 0.723
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)
0.000 0.278 0.722
K90-K93 Other diseases of the digestive system
0.000 0.278 0.722
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.279 0.721
H35.2 Other proliferative retinopathy
0.000 0.280 0.720
Chapter XI Diseases of the digestive system
0.000 0.280 0.720
H34.9 Retinal vascular occlusion, unspecified
0.000 0.282 0.718
E20-E35 Disorders of other endocrine glands
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
E27 Other disorders of adrenal gland
0.000 0.283 0.717
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.284 0.716
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.284 0.716
M07.5 Arthropathy in ulcerative colitis
0.000 0.284 0.715
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.284 0.715
M07.2 Psoriatic spondylitis
0.000 0.284 0.715
M07.1 Arthritis mutilans
0.000 0.284 0.715
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.284 0.715
M07.38 Other psoriatic arthropathies (Other)
0.000 0.285 0.715
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.285 0.715
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.285 0.715
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.286 0.714
G37.5 Concentric sclerosis [Balo]
0.713 0.286 0.000
G37.4 Subacute necrotising myelitis
0.713 0.286 0.000
G37.2 Central pontine myelinolysis
0.713 0.286 0.000
G37.1 Central demyelination of corpus callosum
0.713 0.286 0.000
G37.0 Diffuse sclerosis
0.713 0.286 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.288 0.712
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.288 0.712
M35.5 Multifocal fibrosclerosis
0.000 0.288 0.712
E70 Disorders of aromatic amino-acid metabolism
0.000 0.289 0.711
H30 Chorioretinal inflammation
0.000 0.289 0.711
L44 Other papulosquamous disorders
0.000 0.290 0.710
L41 Parapsoriasis
0.000 0.290 0.710
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.290 0.710
M31.7 Microscopic polyangiitis
0.000 0.290 0.710
E27.1 Primary adrenocortical insufficiency
0.000 0.293 0.707
D50 Iron deficiency anaemia
0.000 0.294 0.706
L40.4 Guttate psoriasis
0.000 0.295 0.705
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.295 0.705
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.295 0.705
M49 Spondylopathies in diseases classified elsewhere
0.000 0.295 0.705
E40-E46 Malnutrition
0.000 0.295 0.704
L85 Other epidermal thickening
0.000 0.298 0.702
H34.1 Central retinal artery occlusion
0.000 0.300 0.700
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.302 0.698
M06.38 Rheumatoid nodule (Other)
0.000 0.302 0.698
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.302 0.698
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.302 0.698
M06.33 Rheumatoid nodule (Forearm)
0.000 0.302 0.698
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.302 0.698
E83.5 Disorders of calcium metabolism
0.698 0.302 0.001
E74 Other disorders of carbohydrate metabolism
0.000 0.302 0.698
D50.9 Iron deficiency anaemia, unspecified
0.000 0.304 0.696
M05.2 Rheumatoid vasculitis
0.000 0.304 0.695
J43.1 Panlobular emphysema
0.000 0.304 0.695
J43.0 MacLeod's syndrome
0.000 0.304 0.695
H54.1 Blindness, one eye, low vision, other eye
0.000 0.305 0.695
M24.7 Protrusio acetabuli
0.000 0.306 0.694
M31.3 Wegener's granulomatosis
0.000 0.306 0.694
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.307 0.693
M80.98 Unspecified osteoporosis with pathological fracture (Other)
0.000 0.307 0.693
E11.0 With coma
0.000 0.307 0.693
E88.2 Lipomatosis, not elsewhere classified
0.000 0.307 0.693
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.308 0.692
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.308 0.692
M06.1 Adult-onset Still's disease
0.000 0.309 0.691
H43-H45 Disorders of vitreous body and globe
0.000 0.310 0.690
L92.0 Granuloma annulare
0.000 0.310 0.690
E06.5 Other chronic thyroiditis
0.000 0.311 0.689
E56 Other vitamin deficiencies
0.000 0.311 0.689
E83.3 Disorders of phosphorus metabolism
0.683 0.311 0.006
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.311 0.689
K75 Other inflammatory liver diseases
0.000 0.312 0.688
K70-K77 Diseases of liver
0.000 0.312 0.688
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.000 0.312 0.688
M24.11 Other articular cartilage disorders (Shoulder region)
0.000 0.316 0.684
M31.8 Other specified necrotising vasculopathies
0.000 0.316 0.684
K75.4 Autoimmune hepatitis
0.000 0.317 0.683
M86 Osteomyelitis
0.000 0.319 0.681
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.322 0.678
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.000 0.322 0.678
M06.0 Seronegative rheumatoid arthritis
0.000 0.322 0.678
E51 Thiamine deficiency
0.000 0.323 0.677
E77 Disorders of glycoprotein metabolism
0.000 0.324 0.676
E76 Disorders of glycosaminoglycan metabolism
0.000 0.324 0.676
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.324 0.676
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.324 0.676
M82 Osteoporosis in diseases classified elsewhere
0.000 0.324 0.676
M07.6 Other enteropathic arthropathies
0.000 0.324 0.676
M00-M03 Infectious arthropathies
0.000 0.324 0.676
H34.2 Other retinal artery occlusions
0.000 0.325 0.675
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.325 0.674
J39.8 Other specified diseases of upper respiratory tract
0.000 0.328 0.672
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.328 0.672
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.328 0.672
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.328 0.672
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.328 0.672
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.328 0.672
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.328 0.672
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.328 0.672
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.328 0.672
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.328 0.672
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.000 0.328 0.671
E14.5 With peripheral circulatory complications
0.000 0.329 0.671
E03.1 Congenital hypothyroidism without goitre
0.000 0.329 0.671
M34.1 CR(E)ST syndrome
0.000 0.329 0.671
E07 Other disorders of thyroid
0.000 0.329 0.670
M12.3 Palindromic rheumatism
0.000 0.331 0.669
M67 Other disorders of synovium and tendon
0.000 0.331 0.669
M32 Systemic lupus erythematosus
0.000 0.331 0.669
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.000 0.332 0.668
L85.8 Other specified epidermal thickening
0.000 0.333 0.667
H35.6 Retinal haemorrhage
0.000 0.333 0.667
K75.8 Other specified inflammatory liver diseases
0.000 0.333 0.667
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.336 0.663
M31.4 Aortic arch syndrome [Takayasu]
0.000 0.337 0.663
M31.2 Lethal midline granuloma
0.000 0.337 0.663
E88.8 Other specified metabolic disorders
0.000 0.337 0.663
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.337 0.662
E63 Other nutritional deficiencies
0.000 0.337 0.662
E50 Vitamin A deficiency
0.000 0.337 0.662
E60 Dietary zinc deficiency
0.000 0.337 0.662
E59 Dietary selenium deficiency
0.000 0.337 0.662
E52 Niacin deficiency [pellagra]
0.000 0.337 0.662
E11.5 With peripheral circulatory complications
0.000 0.338 0.662
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.000 0.339 0.660
L87 Transepidermal elimination disorders
0.000 0.339 0.660
L86 Keratoderma in diseases classified elsewhere
0.000 0.339 0.660
E83.9 Disorder of mineral metabolism, unspecified
0.645 0.339 0.015
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.340 0.660
E78.8 Other disorders of lipoprotein metabolism
0.000 0.341 0.659
L12 Pemphigoid
0.000 0.341 0.659
M31.1 Thrombotic microangiopathy
0.000 0.342 0.657
H20 Iridocyclitis
0.000 0.344 0.656
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.344 0.656
J45.1 Nonallergic asthma
0.000 0.344 0.656
H33.1 Retinoschisis and retinal cysts
0.000 0.345 0.655
M94 Other disorders of cartilage
0.000 0.346 0.654
M06.8 Other specified rheumatoid arthritis
0.000 0.346 0.653
J96 Respiratory failure, not elsewhere classified
0.000 0.348 0.652
L13 Other bullous disorders
0.000 0.349 0.651
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.350 0.650
M30.0 Polyarteritis nodosa
0.000 0.350 0.650
E78.3 Hyperchylomicronaemia
0.000 0.352 0.648
E14.4 With neurological complications
0.000 0.352 0.648
J20-J22 Other acute lower respiratory infections
0.000 0.353 0.647
L94.2 Calcinosis cutis
0.000 0.356 0.644
E72 Other disorders of amino-acid metabolism
0.000 0.358 0.642
E61 Deficiency of other nutrient elements
0.000 0.358 0.642
E53.1 Pyridoxine deficiency
0.000 0.358 0.642
E53.0 Riboflavin deficiency
0.000 0.358 0.642
E54 Ascorbic acid deficiency
0.000 0.359 0.641
E06.9 Thyroiditis, unspecified
0.000 0.359 0.641
H54.9 Unspecified visual impairment (binocular)
0.000 0.360 0.640
H20.0 Acute and subacute iridocyclitis
0.000 0.362 0.638
H54.5 Low vision, one eye
0.000 0.363 0.637
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)
0.000 0.363 0.637
K73 Chronic hepatitis, not elsewhere classified
0.000 0.364 0.636
M49.5 Collapsed vertebra in diseases classified elsewhere
0.000 0.367 0.633
J95.5 Postprocedural subglottic stenosis
0.000 0.368 0.632
J95.4 Mendelson's syndrome
0.000 0.368 0.632
J95.3 Chronic pulmonary insufficiency following surgery
0.000 0.368 0.632
J95.2 Acute pulmonary insufficiency following nonthoracic surgery
0.000 0.368 0.632
J95.1 Acute pulmonary insufficiency following thoracic surgery
0.000 0.368 0.632
E06.4 Drug-induced thyroiditis
0.000 0.368 0.631
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.368 0.631
E06.1 Subacute thyroiditis
0.000 0.368 0.631
E06.0 Acute thyroiditis
0.000 0.368 0.631
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.369 0.631
M15 Polyarthrosis
0.000 0.369 0.631
M34.8 Other forms of systemic sclerosis
0.000 0.372 0.628
L92.2 Granuloma faciale [eosinophilic granuloma of skin]
0.000 0.372 0.628
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.000 0.373 0.627
H54.3 Unqualified visual loss, both eyes
0.000 0.374 0.626
M86.9 Osteomyelitis, unspecified
0.000 0.374 0.626
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.374 0.626
E79 Disorders of purine and pyrimidine metabolism
0.000 0.376 0.624
M60-M63 Disorders of muscles
0.000 0.377 0.623
M14 Arthropathies in other diseases classified elsewhere
0.000 0.377 0.623
E11.4 With neurological complications
0.000 0.377 0.623
H54.6 Unqualified visual loss, one eye
0.000 0.379 0.621
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.379 0.621
H34.0 Transient retinal artery occlusion
0.000 0.380 0.620
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.383 0.617
E73 Lactose intolerance
0.000 0.383 0.616
K90.9 Intestinal malabsorption, unspecified
0.000 0.383 0.617
L95 Vasculitis limited to skin, not elsewhere classified
0.000 0.386 0.614
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.386 0.614
E89.5 Postprocedural testicular hypofunction
0.000 0.386 0.614
E89.1 Postprocedural hypoinsulinaemia
0.000 0.386 0.614
M24.0 Loose body in joint
0.000 0.387 0.613
M12.2 Villonodular synovitis (pigmented)
0.000 0.388 0.612
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.388 0.612
E78.1 Pure hyperglyceridaemia
0.000 0.388 0.611
J41 Simple and mucopurulent chronic bronchitis
0.000 0.390 0.609
M24.75 Protrusio acetabuli-Pelvic/thigh
0.000 0.391 0.609
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.392 0.608
H31 Other disorders of choroid
0.000 0.394 0.606
J37 Chronic laryngitis and laryngotracheitis
0.000 0.394 0.606
H35.1 Retinopathy of prematurity
0.000 0.394 0.606
G36.0 Neuromyelitis optica [Devic]
0.605 0.395 0.000
J39.0 Retropharyngeal and parapharyngeal abscess
0.000 0.396 0.604
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.000 0.398 0.602
D62 Acute posthaemorrhagic anaemia
0.000 0.398 0.602
H10-H13 Disorders of conjunctiva
0.000 0.398 0.602
M24.6 Ankylosis of joint
0.000 0.399 0.601
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.399 0.601
M65.9 Synovitis and tenosynovitis, unspecified
0.000 0.401 0.599
M24.5 Contracture of joint
0.000 0.403 0.597
L90.8 Other atrophic disorders of skin
0.000 0.404 0.596
M35.8 Other specified systemic involvement of connective tissue
0.000 0.407 0.593
H35.7 Separation of retinal layers
0.000 0.408 0.592
M31.9 Necrotising vasculopathy, unspecified
0.000 0.409 0.591
E89.2 Postprocedural hypoparathyroidism
0.000 0.409 0.591
J95.9 Postprocedural respiratory disorder, unspecified
0.000 0.409 0.591
M12.5 Traumatic arthropathy
0.000 0.411 0.589
E78.0 Pure hypercholesterolaemia
0.000 0.411 0.589
M66 Spontaneous rupture of synovium and tendon
0.000 0.411 0.589
L92.1 Necrobiosis lipoidica, not elsewhere classified
0.000 0.412 0.588
M82.1 Osteoporosis in endocrine disorders
0.000 0.413 0.587
M49.54 Collapsed vertebra in diseases classified elsewhere (Thoracic region)
0.000 0.413 0.587
M12.8 Other specific arthropathies, not elsewhere classified
0.000 0.413 0.587
M12.4 Intermittent hydrarthrosis
0.000 0.413 0.586
M12.1 Kaschin-Beck disease
0.000 0.413 0.586
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.000 0.413 0.586
E11.6 With other specified complications
0.000 0.415 0.585
D51 Vitamin B12 deficiency anaemia
0.000 0.415 0.585
M34.2 Systemic sclerosis induced by drugs and chemicals
0.000 0.416 0.584
M24.9 Joint derangement, unspecified
0.000 0.417 0.583
M34.0 Progressive systemic sclerosis
0.000 0.417 0.583
M83 Adult osteomalacia
0.000 0.417 0.583
E55 Vitamin D deficiency
0.000 0.418 0.581
L83 Acanthosis nigricans
0.000 0.419 0.581
M89 Other disorders of bone
0.000 0.420 0.580
L90.9 Atrophic disorder of skin, unspecified
0.000 0.422 0.578
L90.6 Striae atrophicae
0.000 0.422 0.578
L90.4 Acrodermatitis chronica atrophicans
0.000 0.422 0.578
L90.3 Atrophoderma of Pasini and Pierini
0.000 0.422 0.578
L90.2 Anetoderma of Jadassohn-Pellizzari
0.000 0.422 0.578
L90.1 Anetoderma of Schweninger-Buzzi
0.000 0.422 0.578
J99.0 Rheumatoid lung disease
0.000 0.422 0.578
M12.39 Palindromic rheumatism (Site unspecified)
0.000 0.422 0.578
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.000 0.424 0.576
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]
0.000 0.424 0.576
M30.2 Juvenile polyarteritis
0.000 0.424 0.576
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.425 0.574
J45.8 Mixed asthma
0.000 0.425 0.574
M88 Paget's disease of bone [osteitis deformans]
0.000 0.426 0.574
E89.4 Postprocedural ovarian failure
0.000 0.427 0.573
E13 Other specified diabetes mellitus
0.000 0.427 0.572
M24.15 Other articular cartilage disorders (Pelvic region and thigh)
0.000 0.427 0.572
E84 Cystic fibrosis
0.000 0.429 0.570
D53 Other nutritional anaemias
0.000 0.431 0.569
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.432 0.568
E83.8 Other disorders of mineral metabolism
0.547 0.433 0.020
E83.2 Disorders of zinc metabolism
0.547 0.433 0.020
E83.0 Disorders of copper metabolism
0.547 0.433 0.020
K90.3 Pancreatic steatorrhoea
0.000 0.433 0.567
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.433 0.567
K90.1 Tropical sprue
0.000 0.433 0.567
L14 Bullous disorders in diseases classified elsewhere
0.000 0.433 0.567
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.433 0.566
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.436 0.564
M34.9 Systemic sclerosis, unspecified
0.000 0.438 0.562
H34.8 Other retinal vascular occlusions
0.000 0.438 0.562
L12.1 Cicatricial pemphigoid
0.000 0.438 0.561
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.439 0.561
L88 Pyoderma gangrenosum
0.000 0.440 0.560
M65.2 Calcific tendinitis
0.000 0.440 0.559
M65.0 Abscess of tendon sheath
0.000 0.442 0.558
D64.4 Congenital dyserythropoietic anaemia
0.000 0.442 0.558
D64.3 Other sideroblastic anaemias
0.000 0.442 0.558
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.442 0.558
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.442 0.558
D64.0 Hereditary sideroblastic anaemia
0.000 0.442 0.558
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.443 0.556
M80.4 Drug-induced osteoporosis with pathological fracture
0.000 0.445 0.555
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture
0.000 0.445 0.555
M80.2 Osteoporosis of disuse with pathological fracture
0.000 0.445 0.555
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.001 0.446 0.553
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.447 0.553
M67.8 Other specified disorders of synovium and tendon
0.000 0.447 0.553

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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