TreeWAS – Variant ID: rs2516491

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
E05.0 Thyrotoxicosis with diffuse goitre	1.000	0.000	0.000
E10.9 Without complications	1.000	0.000	0.000
E10.3 With ophthalmic complications	1.000	0.000	0.000
H36.0 Diabetic retinopathy	1.000	0.000	0.000
K90.0 Coeliac disease	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
D60-D64 Aplastic and other anaemias	1.000	0.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
E10.1 With ketoacidosis	1.000	0.000	0.000
E16.2 Hypoglycaemia, unspecified	1.000	0.000	0.000
Chapter VII Diseases of the eye and adnexa	1.000	0.000	0.000
E03 Other hypothyroidism	1.000	0.000	0.000
M35.0 Sicca syndrome [Sjogren]	1.000	0.000	0.000
E16 Other disorders of pancreatic internal secretion	1.000	0.000	0.000
H30-H36 Disorders of choroid and retina	1.000	0.000	0.000
E14 Unspecified diabetes mellitus	1.000	0.000	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	1.000	0.000	0.000
D64 Other anaemias	1.000	0.000	0.000
D64.9 Anaemia, unspecified	1.000	0.000	0.000
H36 Retinal disorders in diseases classified elsewhere	1.000	0.000	0.000
N00-N08 Glomerular diseases	1.000	0.000	0.000
K50 Crohn's disease [regional enteritis]	0.000	0.000	1.000
E10.4 With neurological complications	1.000	0.000	0.000
K90 Intestinal malabsorption	0.999	0.001	0.000
E20-E35 Disorders of other endocrine glands	0.999	0.001	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.999	0.001	0.000
N05 Unspecified nephritic syndrome	0.999	0.001	0.000
E14.3 With ophthalmic complications	0.998	0.002	0.000
E10.2 With renal complications	0.998	0.002	0.000
D69 Purpura and other haemorrhagic conditions	0.998	0.002	0.000
E27 Other disorders of adrenal gland	0.997	0.003	0.000
K50-K52 Noninfective enteritis and colitis	0.007	0.003	0.990
E27.1 Primary adrenocortical insufficiency	0.997	0.003	0.000
K50.9 Crohn's disease, unspecified	0.000	0.005	0.995
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.994	0.006	0.000
N04 Nephrotic syndrome	0.994	0.006	0.000
N08 Glomerular disorders in diseases classified elsewhere	0.994	0.006	0.000
M35 Other systemic involvement of connective tissue	0.993	0.007	0.000
D61 Other aplastic anaemias	0.993	0.007	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.992	0.008	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.991	0.009	0.000
K51 Ulcerative colitis	0.000	0.009	0.991
K50.0 Crohn's disease of small intestine	0.000	0.009	0.991
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.990	0.010	0.000
M20-M25 Other joint disorders	0.989	0.011	0.000
K51.9 Ulcerative colitis, unspecified	0.000	0.014	0.986
L40.9 Psoriasis, unspecified	0.000	0.014	0.986
K50.1 Crohn's disease of large intestine	0.000	0.015	0.985
C85.1 B-cell lymphoma, unspecified	0.984	0.016	0.000
K90.9 Intestinal malabsorption, unspecified	0.983	0.017	0.000
N08.3 Glomerular disorders in diabetes mellitus	0.983	0.017	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.982	0.018	0.000
K90-K93 Other diseases of the digestive system	0.982	0.018	0.000
Chapter I Certain infectious and parasitic diseases	0.981	0.019	0.000
Chapter XI Diseases of the digestive system	0.981	0.019	0.000
K70-K77 Diseases of liver	0.980	0.020	0.000
N04.9 Unspecified	0.979	0.021	0.000
D61.9 Aplastic anaemia, unspecified	0.979	0.021	0.000
K75 Other inflammatory liver diseases	0.979	0.021	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.978	0.022	0.000
C81 Hodgkin's disease	0.977	0.023	0.000
K75.4 Autoimmune hepatitis	0.977	0.023	0.000
H43-H45 Disorders of vitreous body and globe	0.973	0.027	0.000
D50-D53 Nutritional anaemias	0.972	0.028	0.000
B35-B49 Mycoses	0.972	0.028	0.000
N05.2 Diffuse membranous glomerulonephritis	0.970	0.030	0.000
Chapter XIV Diseases of the genitourinary system	0.969	0.031	0.000
C83.3 Large cell (diffuse)	0.968	0.032	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.967	0.033	0.000
H43.1 Vitreous haemorrhage	0.964	0.036	0.000
H43 Disorders of vitreous body	0.964	0.036	0.000
B37 Candidiasis	0.962	0.038	0.000
N05.9 Unspecified	0.960	0.040	0.000
N17-N19 Renal failure	0.958	0.042	0.000
N18 Chronic renal failure	0.949	0.051	0.000
M60-M63 Disorders of muscles	0.943	0.057	0.000
L40 Psoriasis	0.005	0.057	0.938
D80-D89 Certain disorders involving the immune mechanism	0.941	0.059	0.000
D69.4 Other primary thrombocytopenia	0.941	0.059	0.000
N18.9 Chronic renal failure, unspecified	0.941	0.059	0.000
B37.0 Candidal stomatitis	0.937	0.063	0.000
E14.9 Without complications	0.935	0.065	0.000
K73 Chronic hepatitis, not elsewhere classified	0.935	0.065	0.000
J44 Other chronic obstructive pulmonary disease	0.933	0.067	0.000
C81.1 Nodular sclerosis	0.932	0.068	0.000
J40-J47 Chronic lower respiratory diseases	0.931	0.069	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.930	0.070	0.000
M86-M90 Other osteopathies	0.929	0.071	0.000
Chapter X Diseases of the respiratory system	0.924	0.076	0.000
H25-H28 Disorders of lens	0.923	0.077	0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.919	0.081	0.000
E22 Hyperfunction of pituitary gland	0.916	0.084	0.000
E10.0 With coma	0.915	0.085	0.000
H04 Disorders of lachrymal system	0.915	0.085	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.912	0.088	0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.912	0.088	0.000
B25-B34 Other viral diseases	0.911	0.089	0.000
E07 Other disorders of thyroid	0.908	0.092	0.000
J45 Asthma	0.906	0.094	0.000
K50.8 Other Crohn's disease	0.000	0.096	0.904
N05.1 Focal and segmental glomerular lesions	0.903	0.097	0.000
B37.8 Candidiasis of other sites	0.902	0.098	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.000	0.099	0.901
H30 Chorioretinal inflammation	0.901	0.099	0.000
N03 Chronic nephritic syndrome	0.897	0.103	0.000
J45.9 Asthma, unspecified	0.896	0.104	0.000
D68 Other coagulation defects	0.895	0.105	0.000
C91 Lymphoid leukaemia	0.894	0.106	0.000
K51.2 Ulcerative (chronic) proctitis	0.000	0.107	0.893
K73.2 Chronic active hepatitis, not elsewhere classified	0.891	0.109	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.890	0.110	0.000
D51 Vitamin B12 deficiency anaemia	0.888	0.112	0.000
C81.9 Hodgkin's disease, unspecified	0.885	0.115	0.000
N08.5 Glomerular disorders in systemic connective tissue disorders	0.881	0.119	0.000
N04.2 Diffuse membranous glomerulonephritis	0.880	0.120	0.000
M21 Other acquired deformities of limbs	0.880	0.120	0.000
L40.0 Psoriasis vulgaris	0.001	0.122	0.877
H26 Other cataract	0.878	0.122	0.000
M34 Systemic sclerosis	0.878	0.122	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.876	0.124	0.000
E10.7 With multiple complications	0.874	0.126	0.000
H06.2 Dysthyroid exophthalmos	0.873	0.127	0.000
M32 Systemic lupus erythematosus	0.869	0.131	0.000
N17 Acute renal failure	0.868	0.132	0.000
H04.8 Other disorders of lachrymal system	0.868	0.132	0.000
N18.3 Chronic kidney disease, stage 3	0.865	0.135	0.000
D80 Immunodeficiency with predominantly antibody defects	0.864	0.136	0.000
B15-B19 Viral hepatitis	0.861	0.139	0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis	0.860	0.140	0.000
M60 Myositis	0.857	0.143	0.000
B25 Cytomegaloviral disease	0.856	0.144	0.000
D68.8 Other specified coagulation defects	0.849	0.151	0.000
K75.8 Other specified inflammatory liver diseases	0.848	0.152	0.000
H26.9 Cataract, unspecified	0.846	0.154	0.000
M89 Other disorders of bone	0.842	0.158	0.000
M62 Other disorders of muscle	0.841	0.159	0.000
L40-L45 Papulosquamous disorders	0.778	0.161	0.061
C91.1 Chronic lymphocytic leukaemia	0.839	0.161	0.000
C83.0 Small cell (diffuse)	0.839	0.161	0.000
D61.1 Drug-induced aplastic anaemia	0.838	0.162	0.000
E14.1 With ketoacidosis	0.836	0.164	0.000
K51.4 Pseudopolyposis of colon	0.000	0.164	0.836
Chapter XX External causes of morbidity and mortality	0.835	0.165	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.834	0.166	0.000
L20-L30 Dermatitis and eczema	0.832	0.168	0.000
D62 Acute posthaemorrhagic anaemia	0.831	0.169	0.000
R31 Unspecified haematuria	0.000	0.170	0.830
H30.9 Chorioretinal inflammation, unspecified	0.829	0.171	0.000
H04.4 Chronic inflammation of lachrymal passages	0.827	0.173	0.000
M35.1 Other overlap syndromes	0.823	0.177	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.822	0.178	0.000
C83.7 Burkitt's tumour	0.822	0.178	0.000
D69.0 Allergic purpura	0.821	0.179	0.000
E10.5 With peripheral circulatory complications	0.821	0.179	0.000
N04.1 Focal and segmental glomerular lesions	0.821	0.179	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.821	0.179	0.000
M86 Osteomyelitis	0.820	0.180	0.000
K51.5 Mucosal proctocolitis	0.000	0.181	0.819
E06 Thyroiditis	0.819	0.181	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.819	0.181	0.000
D69.5 Secondary thrombocytopenia	0.818	0.182	0.000
E89.0 Postprocedural hypothyroidism	0.817	0.183	0.000
B44 Aspergillosis	0.816	0.184	0.000
D50 Iron deficiency anaemia	0.814	0.186	0.000
M05-M14 Inflammatory polyarthropathies	0.812	0.188	0.000
E70-E90 Metabolic disorders	0.812	0.188	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.812	0.188	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.811	0.189	0.000
H34 Retinal vascular occlusions	0.811	0.189	0.000
D53 Other nutritional anaemias	0.810	0.190	0.000
M22 Disorders of patella	0.810	0.190	0.000
H04.1 Other disorders of lachrymal gland	0.807	0.193	0.000
E14.5 With peripheral circulatory complications	0.807	0.193	0.000
D69.2 Other nonthrombocytopenic purpura	0.806	0.194	0.000
H26.1 Traumatic cataract	0.804	0.196	0.000
D69.8 Other specified haemorrhagic conditions	0.803	0.197	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.803	0.197	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.803	0.197	0.000
K72 Hepatic failure, not elsewhere classified	0.800	0.200	0.000
E14.8 With unspecified complications	0.800	0.200	0.000
M21.1 Varus deformity, not elsewhere classified	0.800	0.200	0.000
L40.5 Arthropathic psoriasis	0.000	0.202	0.798
L40.8 Other psoriasis	0.003	0.203	0.794
N03.1 Focal and segmental glomerular lesions	0.797	0.203	0.000
D68.2 Hereditary deficiency of other clotting factors	0.795	0.205	0.000
J47 Bronchiectasis	0.794	0.206	0.000
V20-V29 Motorcycle rider injured in transport accident	0.794	0.206	0.000
D61.0 Constitutional aplastic anaemia	0.792	0.208	0.000
Y95 Nosocomial condition	0.792	0.208	0.000
H31 Other disorders of choroid	0.791	0.209	0.000
K74 Fibrosis and cirrhosis of liver	0.791	0.209	0.000
E07.8 Other specified disorders of thyroid	0.790	0.209	0.000
E28 Ovarian dysfunction	0.790	0.210	0.000
D50.9 Iron deficiency anaemia, unspecified	0.790	0.210	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.790	0.210	0.000
E14.2 Withrenal complications	0.788	0.212	0.000
B25.9 Cytomegaloviral disease, unspecified	0.785	0.215	0.000
E10.8 With unspecified complications	0.785	0.215	0.000
A15-A19 Tuberculosis	0.785	0.215	0.000
E03.8 Other specified hypothyroidism	0.784	0.216	0.000
L28 Lichen simplex chronicus and prurigo	0.784	0.216	0.000
E31 Polyglandular dysfunction	0.782	0.218	0.000
D64.0 Hereditary sideroblastic anaemia	0.781	0.219	0.000
E22.0 Acromegaly and pituitary gigantism	0.780	0.220	0.000
D52 Folate deficiency anaemia	0.779	0.221	0.000
C81.2 Mixed cellularity	0.778	0.222	0.000
M10 Gout	0.778	0.222	0.000
N17.0 Acute renal failure with tubular necrosis	0.776	0.224	0.000
D64.8 Other specified anaemias	0.776	0.224	0.000
H05 Disorders of orbit	0.775	0.225	0.000
N05.8 Other	0.772	0.228	0.000
M60.9 Myositis, unspecified	0.772	0.228	0.000
M21.8 Other specified acquired deformities of limbs	0.769	0.231	0.000
L29 Pruritus	0.769	0.231	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.769	0.231	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.767	0.233	0.000
D55-D59 Haemolytic anaemias	0.765	0.234	0.000
E07.9 Disorder of thyroid, unspecified	0.765	0.235	0.000
L43 Lichen planus	0.738	0.240	0.022
K71 Toxic liver disease	0.759	0.241	0.000
E10.6 With other specified complications	0.759	0.241	0.000
N17.9 Acute renal failure, unspecified	0.759	0.241	0.000
M34.1 CR(E)ST syndrome	0.759	0.241	0.000
D68.6 Other Thrombophilia	0.758	0.242	0.000
M89.8 Other specified disorders of bone	0.758	0.242	0.000
L10-L14 Bullous disorders	0.755	0.245	0.000
M22.8 Other disorders of patella	0.755	0.245	0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van	0.753	0.247	0.000
E23 Hypofunction and other disorders of pituitary gland	0.752	0.248	0.000
K72.0 Acute and subacute hepatic failure	0.750	0.250	0.000
N18.8 Other chronic renal failure	0.749	0.251	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.749	0.251	0.000
E14.4 With neurological complications	0.749	0.251	0.000
J45.1 Nonallergic asthma	0.747	0.253	0.000
E13 Other specified diabetes mellitus	0.747	0.253	0.000
K90.8 Other intestinal malabsorption	0.747	0.253	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.745	0.255	0.000
B18 Chronic viral hepatitis	0.744	0.256	0.000
E16.1 Other hypoglycaemia	0.744	0.256	0.000
H04.9 Disorder of lachrymal system, unspecified	0.743	0.257	0.000
H03 Disorders of eyelid in diseases classified elsewhere	0.743	0.257	0.000
M15-M19 Arthrosis	0.742	0.258	0.000
B25.0 Cytomegaloviral pneumonitis	0.742	0.258	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.742	0.258	0.000
C88 Malignant immunoproliferative diseases	0.741	0.259	0.000
C84.0 Mycosis fungoides	0.741	0.259	0.000
M87 Osteonecrosis	0.740	0.260	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.740	0.260	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.738	0.262	0.000
K51.8 Other ulcerative colitis	0.000	0.262	0.738
B85-B89 Pediculosis, acariasis and other infestations	0.737	0.263	0.000
K73.9 Chronic hepatitis, unspecified	0.736	0.264	0.000
C84.5 Other and unspecified T-cell lymphomas	0.735	0.265	0.000
B37.7 Candidal septicaemia	0.735	0.265	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.734	0.266	0.000
B37.9 Candidiasis, unspecified	0.732	0.268	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.732	0.268	0.000
D84 Other immunodeficiencies	0.731	0.268	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.730	0.270	0.000
J90-J94 Other diseases of pleura	0.730	0.270	0.000
M35.7 Hypermobility syndrome	0.730	0.270	0.000
C91.9 Lymphoid leukaemia, unspecified	0.730	0.270	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.729	0.271	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.728	0.272	0.000
H26.4 After-cataract	0.728	0.272	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.728	0.272	0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.726	0.274	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.726	0.274	0.000
M32.8 Other forms of systemic lupus erythematosus	0.725	0.275	0.000
E27.8 Other specified disorders of adrenal gland	0.725	0.275	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.724	0.276	0.000
D83 Common variable immunodeficiency	0.723	0.277	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.722	0.278	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.722	0.278	0.000
M62.6 Muscle strain	0.722	0.278	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.721	0.279	0.000
B33 Other viral diseases, not elsewhere classified	0.721	0.279	0.000
K74.6 Other and unspecified cirrhosis of liver	0.719	0.281	0.000
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.717	0.283	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
E03.5 Myxoedema coma	0.717	0.283	0.000
E03.4 Atrophy of thyroid (acquired)	0.717	0.283	0.000
E03.3 Postinfectious hypothyroidism	0.717	0.283	0.000
E03.1 Congenital hypothyroidism without goitre	0.717	0.283	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.717	0.283	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.717	0.283	0.000
E16.4 Abnormal secretion of gastrin	0.717	0.283	0.000
E16.3 Increased secretion of glucagon	0.717	0.283	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.717	0.283	0.000
D64.4 Congenital dyserythropoietic anaemia	0.717	0.283	0.000
D64.3 Other sideroblastic anaemias	0.717	0.283	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.717	0.283	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.717	0.283	0.000
E14.7 With multiple complications	0.717	0.283	0.000
E14.0 With coma	0.717	0.283	0.000
E15 Nondiabetic hypoglycaemic coma	0.717	0.283	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.717	0.283	0.000
L28.0 Lichen simplex chronicus	0.717	0.283	0.000
N07 Hereditary nephropathy, not elsewhere classified	0.717	0.283	0.000
N06 Isolated proteinuria with specified morphological lesion	0.717	0.283	0.000
N01 Rapidly progressive nephritic syndrome	0.717	0.283	0.000
N00 Acute nephritic syndrome	0.717	0.283	0.000
M18 Arthrosis of first carpometacarpal joint	0.717	0.283	0.000
K90.3 Pancreatic steatorrhoea	0.716	0.284	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.716	0.284	0.000
K90.1 Tropical sprue	0.716	0.284	0.000
E05.8 Other thyrotoxicosis	0.716	0.284	0.000
D67 Hereditary factor IX deficiency	0.716	0.284	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.716	0.284	0.000
E32 Diseases of thymus	0.716	0.284	0.000
E30 Disorders of puberty, not elsewhere classified	0.716	0.284	0.000
E25 Adrenogenital disorders	0.716	0.284	0.000
N05.6 Dense deposit disease	0.716	0.284	0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis	0.716	0.284	0.000
N05.0 Minor glomerular abnormality	0.716	0.284	0.000
C81.0 Lymphocytic predominance	0.716	0.284	0.000
D69.1 Qualitative platelet defects	0.715	0.285	0.000
E27.5 Adrenomedullary hyperfunction	0.715	0.285	0.000
E27.0 Other adrenocortical overactivity	0.715	0.285	0.000
M89.9 Disorder of bone, unspecified	0.715	0.285	0.000
C85.0 Lymphosarcoma	0.713	0.287	0.000
V23.4 Driver injured in traffic accident	0.713	0.287	0.000
N04.8 Other	0.713	0.287	0.000
N04.7 Diffuse crescentic glomerulonephritis	0.713	0.287	0.000
N04.6 Dense deposit disease	0.713	0.287	0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis	0.713	0.287	0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis	0.713	0.287	0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis	0.713	0.287	0.000
E14.6 With other specified complications	0.713	0.287	0.000
N08.8 Glomerular disorders in other diseases classified elsewhere	0.712	0.287	0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases	0.712	0.287	0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism	0.712	0.287	0.000
N08.1 Glomerular disorders in neoplastic diseases	0.712	0.287	0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere	0.712	0.287	0.000
E24 Cushing's syndrome	0.712	0.288	0.000
E27.9 Disorder of adrenal gland, unspecified	0.712	0.288	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.712	0.288	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.712	0.288	0.000
M35.5 Multifocal fibrosclerosis	0.712	0.288	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.712	0.288	0.000
H34.8 Other retinal vascular occlusions	0.712	0.288	0.000
L29.2 Pruritus vulvae	0.712	0.288	0.000
D61.8 Other specified aplastic anaemias	0.712	0.288	0.000
D61.3 Idiopathic aplastic anaemia	0.712	0.288	0.000
D61.2 Aplastic anaemia due to other external agents	0.712	0.288	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.711	0.289	0.000
C94 Other leukaemias of specified cell type	0.711	0.289	0.000
L43.9 Lichen planus, unspecified	0.709	0.289	0.001
M60.99 Myositis, unspecified (Site unspecified)	0.709	0.291	0.000
M31 Other necrotising vasculopathies	0.708	0.292	0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis	0.708	0.292	0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.708	0.292	0.000
B16 Acute hepatitis B	0.707	0.293	0.000
B35 Dermatophytosis	0.706	0.294	0.000
M11 Other crystal arthropathies	0.705	0.295	0.000
M10.0 Idiopathic gout	0.704	0.295	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.704	0.296	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.703	0.297	0.000
A75-A79 Rickettsioses	0.703	0.297	0.000
A70-A74 Other diseases caused by chlamydiae	0.703	0.297	0.000
A20-A28 Certain zoonotic bacterial diseases	0.703	0.297	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.703	0.297	0.000
J90 Pleural effusion, not elsewhere classified	0.703	0.297	0.000
K77 Liver disorders in diseases classified elsewhere	0.703	0.297	0.000
K75.2 Nonspecific reactive hepatitis	0.702	0.298	0.000
K75.1 Phlebitis of portal vein	0.702	0.298	0.000
C83.6 Undifferentiated (diffuse)	0.701	0.299	0.000
C83.5 Lymphoblastic (diffuse)	0.701	0.299	0.000
C83.4 Immunoblastic (diffuse)	0.701	0.299	0.000
C83.2 Mixed small and large cell (diffuse)	0.701	0.299	0.000
C81.7 Other Hodgkin's disease	0.701	0.299	0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.701	0.299	0.000
C81.3 Lymphocytic depletion	0.701	0.299	0.000
B49 Unspecified mycosis	0.700	0.300	0.000
H01 Other inflammation of eyelid	0.699	0.301	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.699	0.301	0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.697	0.302	0.000
N03.8 Other	0.697	0.303	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.697	0.303	0.000
B48 Other mycoses, not elsewhere classified	0.697	0.303	0.000
B47 Mycetoma	0.697	0.303	0.000
B46 Zygomycosis	0.697	0.303	0.000
B45 Cryptococcosis	0.697	0.303	0.000
B43 Chromomycosis and phaeomycotic abscess	0.697	0.303	0.000
B42 Sporotrichosis	0.697	0.303	0.000
B41 Paracoccidioidomycosis	0.697	0.303	0.000
B40 Blastomycosis	0.697	0.303	0.000
B39 Histoplasmosis	0.697	0.303	0.000
B38 Coccidioidomycosis	0.697	0.303	0.000
H43.2 Crystalline deposits in vitreous body	0.695	0.305	0.000
M10.9 Gout, unspecified	0.695	0.305	0.000
J41 Simple and mucopurulent chronic bronchitis	0.695	0.305	0.000
C86 Other specified types of T/NK-cell lymphoma	0.694	0.306	0.000
D53.9 Nutritional anaemia, unspecified	0.694	0.306	0.000
H43.0 Vitreous prolapse	0.691	0.309	0.000
B37.6 Candidal endocarditis	0.690	0.310	0.000
B37.5 Candidal meningitis	0.690	0.310	0.000
D82 Immunodeficiency associated with other major defects	0.689	0.310	0.000
M21.9 Acquired deformity of limb, unspecified	0.689	0.311	0.000
M21.0 Valgus deformity, not elsewhere classified	0.688	0.312	0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level	0.687	0.313	0.000
M15 Polyarthrosis	0.687	0.313	0.000
N04.0 Minor glomerular abnormality	0.682	0.317	0.000
B37.1 Pulmonary candidiasis	0.682	0.318	0.000
H27 Other disorders of lens	0.682	0.318	0.000
C84.8 Cutaneous T-cell lymphoma, unspecified	0.681	0.319	0.000
E20 Hypoparathyroidism	0.681	0.319	0.000
C95 Leukaemia of unspecified cell type	0.681	0.319	0.000
L13 Other bullous disorders	0.680	0.320	0.000
E29 Testicular dysfunction	0.678	0.321	0.000
D69.9 Haemorrhagic condition, unspecified	0.678	0.322	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.678	0.322	0.000
H43.9 Disorder of vitreous body, unspecified	0.677	0.323	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.676	0.323	0.000
M61 Calcification and ossification of muscle	0.676	0.323	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.676	0.324	0.000
M34.9 Systemic sclerosis, unspecified	0.676	0.324	0.000
L40.4 Guttate psoriasis	0.004	0.324	0.672
L40.2 Acrodermatitis continua	0.004	0.324	0.672
X20-X29 Contact with venomous animals and plants	0.675	0.325	0.000
D81 Combined immunodeficiencies	0.675	0.325	0.000
M86.1 Other acute osteomyelitis	0.674	0.326	0.000
B44.9 Aspergillosis, unspecified	0.673	0.327	0.000
M34.0 Progressive systemic sclerosis	0.671	0.329	0.000
Y65 Other misadventures during surgical and medical care	0.671	0.329	0.000
B18.1 Chronic viral hepatitis B without delta-agent	0.670	0.329	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.670	0.330	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.670	0.330	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.670	0.330	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.670	0.330	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.669	0.331	0.000
E06.3 Autoimmune thyroiditis	0.669	0.331	0.000
A30-A49 Other bacterial diseases	0.667	0.333	0.000
H05.0 Acute inflammation of orbit	0.667	0.333	0.000
V40-V49 Car occupant injured in transport accident	0.666	0.334	0.000
M88 Paget's disease of bone [osteitis deformans]	0.666	0.334	0.000
D73 Diseases of spleen	0.665	0.335	0.000
B15 Acute hepatitis A	0.665	0.335	0.000
M86.8 Other osteomyelitis	0.662	0.338	0.000
H26.3 Drug-induced cataract	0.662	0.338	0.000
A65-A69 Other spirochaetal diseases	0.661	0.338	0.000
H31.0 Chorioretinal scars	0.661	0.338	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.661	0.339	0.000
M60.2 Foreign body granuloma of soft tissue, not elsewhere classified	0.660	0.340	0.000
N18.4 Chronic kidney disease, stage 4	0.659	0.341	0.000
V22 Motorcycle rider injured in collision with two- or three-wheeled motor vehicle	0.659	0.341	0.000
E28.2 Polycystic ovarian syndrome	0.659	0.341	0.000
K75.9 Inflammatory liver disease, unspecified	0.658	0.342	0.000
N03.9 Unspecified	0.658	0.342	0.000
L40.1 Generalised pustular psoriasis	0.004	0.342	0.654
C83.1 Small cleaved cell (diffuse)	0.657	0.343	0.000
N18.5 Chronic kidney disease, stage 5	0.657	0.343	0.000
H04.3 Acute and unspecified inflammation of lachrymal passages	0.657	0.343	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.657	0.343	0.000
E22.8 Other hyperfunction of pituitary gland	0.657	0.343	0.000
E22.1 Hyperprolactinaemia	0.656	0.343	0.000
H04.0 Dacryoadenitis	0.656	0.344	0.000
D68.0 Von Willebrand's disease	0.655	0.345	0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.654	0.346	0.000
H06.3 Other disorders of orbit in diseases classified elsewhere	0.654	0.346	0.000
H06.1 Parasitic infestation of orbit in diseases classified elsewhere	0.654	0.346	0.000
H06.0 Disorders of lachrymal system in diseases classified elsewhere	0.654	0.346	0.000
B37.3 Candidiasis of vulva and vagina	0.654	0.346	0.000
B30 Viral conjunctivitis	0.653	0.347	0.000
B26 Mumps	0.653	0.347	0.000
E07.1 Dyshormogenetic goitre	0.651	0.349	0.000
E07.0 Hypersecretion of calcitonin	0.651	0.349	0.000
X10-X19 Contact with heat and hot substances	0.651	0.349	0.000
M35.3 Polymyalgia rheumatica	0.651	0.349	0.000
C84.4 Peripheral T-cell lymphoma	0.651	0.349	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.650	0.350	0.000
J46 Status asthmaticus	0.650	0.350	0.000
M87.9 Osteonecrosis, unspecified	0.649	0.351	0.000
A63.0 Anogenital (venereal) warts	0.648	0.352	0.000
H55-H59 Other disorders of eye and adnexa	0.648	0.352	0.000
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.648	0.352	0.000
A15 Respiratory tuberculosis, bacteriologically and histologically confirmed	0.646	0.354	0.000
M62.1 Other rupture of muscle (nontraumatic)	0.646	0.354	0.000
H30.8 Other chorioretinal inflammations	0.646	0.354	0.000
H30.2 Posterior cyclitis	0.646	0.354	0.000
H30.1 Disseminated chorioretinal inflammation	0.646	0.354	0.000
H30.0 Focal chorioretinal inflammation	0.646	0.354	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.646	0.354	0.000
D50.1 Sideropenic dysphagia	0.644	0.356	0.000
L28.1 Prurigo nodularis	0.644	0.356	0.000
N03.7 Diffuse crescentic glomerulonephritis	0.643	0.357	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations