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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant cluster associations

Hospitalization Episode Statistics (HES)

Cluster X0275
log Bayes Factor = 219.726
contains 10 variants:
rs10020951
lBF = 12.587
Chr 4 : 28,372,837
rs75005416
lBF = 13.827
Chr 4 : 152,583,764
rs113898198
lBF = 14.133
Chr 5 : 113,603,570
rs199055
lBF = 13.893
Chr 6 : 23,490,117
rs77141874
lBF = 14.998
Chr 6 : 55,438,094
rs118094226
lBF = 14.816
Chr 6 : 96,569,132
rs117182866
lBF = 23.316
Chr 6 : 112,035,847
rs74729480
lBF = 14.649
Chr 9 : 137,375,254
rs16966833
lBF = 11.257
Chr17 : 30,035,727
rs117803469
lBF = 12.507
Chr20 : 1,600,405
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M19.99 Arthrosis, unspecified (Site unspecified)
1.000 0.000 0.000
M19.9 Arthrosis, unspecified
1.000 0.000 0.000
M25.5 Pain in joint
1.000 0.000 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
1.000 0.000 0.000
M19 Other arthrosis
1.000 0.000 0.000
M20 Acquired deformities of fingers and toes
1.000 0.000 0.000
M25 Other joint disorders, not elsewhere classified
1.000 0.000 0.000
M47 Spondylosis
1.000 0.000 0.000
M50 Cervical disk disorders
1.000 0.000 0.000
M54 Dorsalgia
1.000 0.000 0.000
M79 Other soft tissue disorders, not elsewhere classified
1.000 0.000 0.000
G50-G59 Nerve, nerve root and plexus disorders
1.000 0.000 0.000
G90-G99 Other disorders of the nervous system
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
1.000 0.000 0.000
M15-M19 Arthrosis
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
M45-M49 Spondylopathies
1.000 0.000 0.000
M50-M54 Other dorsopathies
1.000 0.000 0.000
M70-M79 Other soft tissue disorders
1.000 0.000 0.000
N70-N77 Inflammatory diseases of female pelvic organs
1.000 0.000 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
M20.4 Other hammer toe(s) (acquired)
1.000 0.000 0.000
M79.6 Pain in limb
1.000 0.000 0.000
M51 Other intervertebral disk disorders
1.000 0.000 0.000
E20-E35 Disorders of other endocrine glands
1.000 0.000 0.000
E70-E90 Metabolic disorders
1.000 0.000 0.000
S00-S09 Injuries to the head
1.000 0.000 0.000
M24 Other specific joint derangements
1.000 0.000 0.000
N80-N98 Noninflammatory disorders of female genital tract
1.000 0.000 0.000
G56 Mononeuropathies of upper limb
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
1.000 0.000 0.000
S70-S79 Injuries to the hip and thigh
1.000 0.000 0.000
G56.0 Carpal tunnel syndrome
1.000 0.000 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
1.000 0.000 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
1.000 0.000 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
1.000 0.000 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
1.000 0.000 0.000
E11 Non-insulin-dependent diabetes mellitus
1.000 0.000 0.000
M13 Other arthritis
1.000 0.000 0.000
Chapter VIII Diseases of the ear and mastoid process
1.000 0.000 0.000
M54.5 Low back pain
1.000 0.000 0.000
N00-N08 Glomerular diseases
1.000 0.000 0.000
M47.9 Spondylosis, unspecified
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
M23 Internal derangement of knee
1.000 0.000 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
1.000 0.000 0.000
R20 Disturbances of skin sensation
0.999 0.001 0.000
N76 Other inflammation of vagina and vulva
0.999 0.001 0.000
N10-N16 Renal tubulo-interstitial diseases
0.999 0.001 0.000
M19.0 Primary arthrosis of other joints
0.999 0.001 0.000
M80-M85 Disorders of bone density and structure
0.999 0.001 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.999 0.001 0.000
M13.9 Arthritis, unspecified
0.999 0.001 0.000
M46 Other inflammatory spondylopathies
0.999 0.001 0.000
M18 Arthrosis of first carpometacarpal joint
0.999 0.001 0.000
M23.3 Other meniscus derangements
0.999 0.001 0.000
N13 Obstructive and reflux uropathy
0.999 0.001 0.000
S60-S69 Injuries to the wrist and hand
0.999 0.001 0.000
S06 Intracranial injury
0.999 0.001 0.000
M50.0 Cervical disk disorder with myelopathy
0.999 0.001 0.000
M48 Other spondylopathies
0.999 0.001 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.999 0.001 0.000
M51.2 Other specified intervertebral disk displacement
0.999 0.001 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.999 0.001 0.000
M06 Other rheumatoid arthritis
0.999 0.001 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.998 0.002 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.998 0.002 0.000
M84 Disorders of continuity of bone
0.998 0.002 0.000
D00-D09 In situ neoplasms
0.998 0.002 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.998 0.002 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.997 0.003 0.000
G93 Other disorders of brain
0.997 0.003 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.997 0.003 0.000
M48.0 Spinal stenosis
0.997 0.003 0.000
M20.5 Other deformities of toe(s) (acquired)
0.997 0.003 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.996 0.004 0.000
L08 Other local infections of skin and subcutaneous tissue
0.996 0.004 0.000
M47.8 Other spondylosis
0.996 0.004 0.000
M50.2 Other cervical disk displacement
0.996 0.004 0.000
M54.59 Low back pain (Site unspecified)
0.996 0.004 0.000
M21 Other acquired deformities of limbs
0.995 0.005 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.995 0.005 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.995 0.005 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.995 0.005 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.995 0.005 0.000
M79.0 Rheumatism, unspecified
0.995 0.005 0.000
N89 Other noninflammatory disorders of vagina
0.995 0.005 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.994 0.006 0.000
M25.51 Pain in joint (Shoulder region)
0.994 0.006 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.993 0.007 0.000
M06.9 Rheumatoid arthritis, unspecified
0.992 0.008 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.992 0.008 0.000
H30-H36 Disorders of choroid and retina
0.992 0.008 0.000
S72 Fracture of femur
0.992 0.008 0.000
F30-F39 Mood [affective] disorders
0.991 0.009 0.000
M79.1 Myalgia
0.991 0.009 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.991 0.009 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.991 0.009 0.000
L20-L30 Dermatitis and eczema
0.990 0.010 0.000
M19.98 Arthrosis, unspecified (Other)
0.990 0.010 0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.989 0.011 0.000
E11.4 With neurological complications
0.989 0.011 0.000
S40-S49 Injuries to the shoulder and upper arm
0.989 0.011 0.000
Q60-Q64 Congenital malformations of the urinary system
0.988 0.012 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.988 0.012 0.000
R26 Abnormalities of gait and mobility
0.987 0.013 0.000
H90-H95 Other disorders of ear
0.987 0.013 0.000
N03 Chronic nephritic syndrome
0.987 0.013 0.000
W20-W49 Exposure to inanimate mechanical forces
0.987 0.013 0.000
E27 Other disorders of adrenal gland
0.986 0.014 0.000
E83 Disorders of mineral metabolism
0.986 0.014 0.000
M34 Systemic sclerosis
0.986 0.014 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.986 0.014 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.986 0.014 0.000
M47.82 Other spondylosis (Cervical region)
0.986 0.014 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.986 0.014 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.985 0.015 0.000
H90 Conductive and sensorineural hearing loss
0.984 0.016 0.000
D04 Carcinoma in situ of skin
0.984 0.016 0.000
M24.0 Loose body in joint
0.984 0.016 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.984 0.016 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.984 0.016 0.000
S01 Open wound of head
0.984 0.016 0.000
E86 Volume depletion
0.984 0.016 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.983 0.017 0.000
M79.67 Pain in limb (Ankle and foot)
0.983 0.017 0.000
G82 Paraplegia and tetraplegia
0.982 0.018 0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)
0.982 0.018 0.000
O60-O75 Complications of labour and delivery
0.982 0.018 0.000
S62 Fracture at wrist and hand level
0.981 0.019 0.000
T66-T78 Other and unspecified effects of external causes
0.981 0.019 0.000
T93 Sequelae of injuries of lower limb
0.981 0.019 0.000
R52 Pain, not elsewhere classified
0.981 0.019 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.981 0.019 0.000
S60 Superficial injury of wrist and hand
0.981 0.019 0.000
G40-G47 Episodic and paroxysmal disorders
0.981 0.019 0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)
0.981 0.019 0.000
A30-A49 Other bacterial diseases
0.980 0.020 0.000
H55-H59 Other disorders of eye and adnexa
0.980 0.020 0.000
H65-H75 Diseases of middle ear and mastoid
0.980 0.020 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.980 0.020 0.000
R23 Other skin changes
0.980 0.020 0.000
R52.1 Chronic intractable pain
0.980 0.020 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.979 0.021 0.000
M86-M90 Other osteopathies
0.979 0.021 0.000
N30-N39 Other diseases of urinary system
0.979 0.021 0.000
M25.56 Pain in joint (Lower leg)
0.979 0.021 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.978 0.022 0.000
F33 Recurrent depressive disorder
0.978 0.022 0.000
S40 Superficial injury of shoulder and upper arm
0.978 0.022 0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)
0.978 0.022 0.000
N03.9 Unspecified
0.978 0.022 0.000
M79.69 Pain in limb (Site unspecified)
0.978 0.022 0.000
N89.8 Other specified noninflammatory disorders of vagina
0.978 0.022 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.978 0.022 0.000
N76.0 Acute vaginitis
0.978 0.022 0.000
N94.8 Other specified conditions associated with female genital organs and menstrual cycle
0.977 0.023 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.977 0.023 0.000
S70 Superficial injury of hip and thigh
0.977 0.023 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.977 0.023 0.000
T87 Complications peculiar to reattachment and amputation
0.977 0.023 0.000
E11.2 With renal complications
0.976 0.024 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.976 0.024 0.000
T43.2 Other and unspecified antidepressants
0.975 0.025 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.974 0.026 0.000
M79.64 Pain in limb (Hand)
0.974 0.026 0.000
S06.5 Traumatic subdural haemorrhage
0.974 0.026 0.000
O42 Premature rupture of membranes
0.973 0.027 0.000
E10 Insulin-dependent diabetes mellitus
0.972 0.028 0.000
H35 Other retinal disorders
0.972 0.028 0.000
Y40 Systemic antibiotics
0.971 0.029 0.000
N71 Inflammatory disease of uterus, except cervix
0.971 0.029 0.000
W00-W19 Falls
0.970 0.030 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.970 0.030 0.000
M79.00 Rheumatism, unspecified (Multiple sites)
0.970 0.030 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.970 0.030 0.000
H60-H62 Diseases of external ear
0.970 0.030 0.000
T92 Sequelae of injuries of upper limb
0.969 0.031 0.000
H18 Other disorders of cornea
0.969 0.031 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.969 0.031 0.000
H04 Disorders of lachrymal system
0.968 0.032 0.000
M19.1 Posttraumatic arthrosis of other joints
0.968 0.032 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.968 0.032 0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.968 0.032 0.000
R47-R49 Symptoms and signs involving speech and voice
0.968 0.032 0.000
T93.2 Sequelae of other fractures of lower limb
0.968 0.032 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.967 0.033 0.000
H05 Disorders of orbit
0.967 0.033 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.966 0.034 0.000
L30 Other dermatitis
0.965 0.035 0.000
C64-C68 Malignant neoplasms of urinary tract
0.965 0.035 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.965 0.035 0.000
N36 Other disorders of urethra
0.964 0.036 0.000
M07 Psoriatic and enteropathic arthropathies
0.964 0.036 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.963 0.037 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.963 0.037 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.963 0.037 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.963 0.037 0.000
H90.3 Sensorineural hearing loss, bilateral
0.962 0.038 0.000
H74 Other disorders of middle ear and mastoid
0.962 0.038 0.000
E27.1 Primary adrenocortical insufficiency
0.962 0.038 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.962 0.038 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.961 0.039 0.000
M25.8 Other specified joint disorders
0.961 0.039 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.961 0.039 0.000
M25.50 Pain in joint (Multiple sites)
0.961 0.039 0.000
E83.1 Disorders of iron metabolism
0.961 0.039 0.000
R52.0 Acute pain
0.961 0.039 0.000
H50 Other strabismus
0.960 0.040 0.000
H57 Other disorders of eye and adnexa
0.960 0.040 0.000
H53-H54 Visual disturbances and blindness
0.960 0.040 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.959 0.041 0.000
Chapter IX Diseases of the circulatory system
0.958 0.042 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.958 0.042 0.000
S06.0 Concussion
0.957 0.043 0.000
R50-R69 General symptoms and signs
0.957 0.043 0.000
M79.19 Myalgia (Site unspecified)
0.957 0.043 0.000
S01.0 Open wound of scalp
0.956 0.044 0.000
S70.9 Superficial injury of hip and thigh, unspecified
0.956 0.044 0.000
F01 Vascular dementia
0.956 0.044 0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)
0.956 0.044 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.955 0.045 0.000
M54.1 Radiculopathy
0.955 0.045 0.000
R25 Abnormal involuntary movements
0.955 0.045 0.000
B35-B49 Mycoses
0.955 0.045 0.000
G91 Hydrocephalus
0.954 0.046 0.000
M50.1 Cervical disk disorder with radiculopathy
0.953 0.047 0.000
M51.8 Other specified intervertebral disk disorders
0.953 0.047 0.000
E21.3 Hyperparathyroidism, unspecified
0.952 0.048 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.952 0.048 0.000
M34.9 Systemic sclerosis, unspecified
0.952 0.048 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.952 0.048 0.000
M19.90 Arthrosis, unspecified (Multiple sites)
0.952 0.048 0.000
S40.0 Contusion of shoulder and upper arm
0.952 0.048 0.000
D09 Carcinoma in situ of other and unspecified sites
0.952 0.048 0.000
T79-T79 Certain early complications of trauma
0.951 0.049 0.000
M05 Seropositive rheumatoid arthritis
0.951 0.049 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.951 0.049 0.000
L50-L54 Urticaria and erythema
0.951 0.049 0.000
E11.5 With peripheral circulatory complications
0.951 0.049 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.951 0.049 0.000
F43 Reaction to severe stress, and adjustment disorders
0.950 0.050 0.000
X60-X84 Intentional self-harm
0.950 0.050 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.949 0.051 0.000
S90-S99 Injuries to the ankle and foot
0.949 0.051 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.949 0.051 0.000
R49 Voice disturbances
0.949 0.051 0.000
F01.9 Vascular dementia, unspecified
0.948 0.052 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.948 0.052 0.000
S72.2 Subtrochanteric fracture
0.948 0.052 0.000
N70 Salpingitis and oophoritis
0.948 0.052 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.948 0.052 0.000
M54.3 Sciatica
0.947 0.053 0.000
O20 Haemorrhage in early pregnancy
0.947 0.053 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.947 0.053 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.946 0.054 0.000
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)
0.946 0.054 0.000
M24.2 Disorder of ligament
0.945 0.055 0.000
N76.4 Abscess of vulva
0.944 0.056 0.000
Q00-Q07 Congenital malformations of the nervous system
0.944 0.056 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.944 0.056 0.000
L60-L75 Disorders of skin appendages
0.944 0.056 0.000
G58 Other mononeuropathies
0.944 0.056 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.943 0.057 0.000
M21.1 Varus deformity, not elsewhere classified
0.942 0.058 0.000
Chapter X Diseases of the respiratory system
0.942 0.058 0.000
Chapter XI Diseases of the digestive system
0.942 0.058 0.000
M24.1 Other articular cartilage disorders
0.941 0.059 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.941 0.059 0.000
H50.1 Divergent concomitant strabismus
0.941 0.059 0.000
T90 Sequelae of injuries of head
0.941 0.059 0.000
Q61 Cystic kidney disease
0.941 0.059 0.000
E29 Testicular dysfunction
0.940 0.060 0.000
S01.9 Open wound of head, part unspecified
0.940 0.060 0.000
H61 Other disorders of external ear
0.940 0.060 0.000
Y52 Agents primarily affecting the cardiovascular system
0.939 0.061 0.000
S60.8 Other superficial injuries of wrist and hand
0.939 0.061 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.939 0.061 0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours
0.939 0.061 0.000
M77 Other enthesopathies
0.939 0.061 0.000
H34 Retinal vascular occlusions
0.939 0.061 0.000
M07.3 Other psoriatic arthropathies
0.939 0.061 0.000
M19.04 Primary arthrosis of other joints (Hand)
0.938 0.062 0.000
M24.07 Loose body in joint (Ankle and foot)
0.938 0.062 0.000
N60-N64 Disorders of breast
0.937 0.063 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.937 0.063 0.000
M79.62 Pain in limb (Upper arm)
0.937 0.063 0.000
G59.0 Diabetic mononeuropathy
0.937 0.063 0.000
M60-M63 Disorders of muscles
0.936 0.064 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.936 0.064 0.000
S79 Other and unspecified injuries of hip and thigh
0.935 0.065 0.000
H35.4 Peripheral retinal degeneration
0.935 0.065 0.000
S72.3 Fracture of shaft of femur
0.935 0.065 0.000
M48.06 Spinal stenosis (Lumbar region)
0.935 0.065 0.000
F60-F69 Disorders of adult personality and behaviour
0.935 0.065 0.000
M06.0 Seronegative rheumatoid arthritis
0.935 0.065 0.000
S10-S19 Injuries to the neck
0.934 0.065 0.000
G82.2 Paraplegia, unspecified
0.934 0.066 0.000
M47.86 Other spondylosis (Lumbar region)
0.934 0.066 0.000
H57.1 Ocular pain
0.934 0.066 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.933 0.067 0.000
M21.0 Valgus deformity, not elsewhere classified
0.933 0.067 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.933 0.067 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.932 0.068 0.000
D39.1 Ovary
0.932 0.068 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.931 0.069 0.000
E83.5 Disorders of calcium metabolism
0.931 0.069 0.000
V80-V89 Other land transport accidents
0.931 0.069 0.000
C45 Mesothelioma
0.930 0.070 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.930 0.070 0.000
N76.8 Other specified inflammation of vagina and vulva
0.930 0.070 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.930 0.070 0.000
R52.9 Pain, unspecified
0.929 0.071 0.000
R26.0 Ataxic gait
0.929 0.071 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.929 0.071 0.000
W22 Striking against or struck by other objects
0.929 0.071 0.000
N36.8 Other specified disorders of urethra
0.929 0.071 0.000
N39 Other disorders of urinary system
0.928 0.072 0.000
M79.10 Myalgia (Multiple sites)
0.928 0.072 0.000
N05 Unspecified nephritic syndrome
0.928 0.072 0.000
S20-S29 Injuries to the thorax
0.927 0.073 0.000
R82 Other abnormal findings in urine
0.927 0.073 0.000
O85-O92 Complications predominantly related to the puerperium
0.927 0.073 0.000
S06.00 Concussion (without open intracranial wound)
0.927 0.073 0.000
M91-M94 Chondropathies
0.927 0.073 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.927 0.073 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.927 0.073 0.000
I05-I09 Chronic rheumatic heart diseases
0.927 0.073 0.000
C01 Malignant neoplasm of base of tongue
0.926 0.074 0.000
T86 Failure and rejection of transplanted organs and tissues
0.926 0.074 0.000
G93.2 Benign intracranial hypertension
0.926 0.074 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.925 0.075 0.000
J30-J39 Other diseases of upper respiratory tract
0.925 0.075 0.000
H04.1 Other disorders of lachrymal gland
0.924 0.076 0.000
M25.54 Pain in joint (Hand)
0.924 0.076 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.924 0.076 0.000
M13.93 Arthritis, unspecified (Forearm)
0.924 0.076 0.000
T87.6 Other and unspecified complications of amputation stump
0.924 0.076 0.000
N04 Nephrotic syndrome
0.923 0.077 0.000
M54.50 Low back pain (Multiple sites in spine)
0.923 0.077 0.000
T78 Adverse effects, not elsewhere classified
0.923 0.077 0.000
N36.0 Urethral fistula
0.923 0.077 0.000
S02 Fracture of skull and facial bones
0.922 0.078 0.000
H35.9 Retinal disorder, unspecified
0.921 0.079 0.000
W44 Foreign body entering into or through eye or natural orifice
0.921 0.079 0.000
O00-O08 Pregnancy with abortive outcome
0.921 0.079 0.000
R20.2 Paraesthesia of skin
0.920 0.080 0.000
H49 Paralytic strabismus
0.919 0.081 0.000
D09.0 Bladder
0.919 0.081 0.000
H10-H13 Disorders of conjunctiva
0.918 0.082 0.000
M86 Osteomyelitis
0.918 0.082 0.000
T68 Hypothermia
0.917 0.083 0.000
L30.9 Dermatitis, unspecified
0.917 0.083 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.917 0.083 0.000
H05.2 Exophthalmic conditions
0.917 0.083 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.917 0.083 0.000
L40-L45 Papulosquamous disorders
0.916 0.084 0.000
S72.20 Subtrochanteric fracture (closed)
0.916 0.084 0.000
N71.1 Chronic inflammatory disease of uterus
0.916 0.084 0.000
G63.2 Diabetic polyneuropathy
0.915 0.085 0.000
M24.02 Loose body in joint (Upper arm)
0.915 0.085 0.000
E10.4 With neurological complications
0.915 0.085 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.915 0.085 0.000
H16 Keratitis
0.914 0.086 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.914 0.086 0.000
C67 Malignant neoplasm of bladder
0.913 0.087 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.913 0.087 0.000
M23.8 Other internal derangements of knee
0.913 0.087 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.913 0.087 0.000
H65 Nonsuppurative otitis media
0.913 0.087 0.000
S72.4 Fracture of lower end of femur
0.913 0.087 0.000
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere
0.912 0.088 0.000
S80-S89 Injuries to the knee and lower leg
0.911 0.089 0.000
C71 Malignant neoplasm of brain
0.911 0.089 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.911 0.089 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.911 0.089 0.000
N82 Fistulae involving female genital tract
0.910 0.090 0.000
H47.3 Other disorders of optic disk
0.910 0.090 0.000
K12 Stomatitis and related lesions
0.910 0.090 0.000
F43.1 Posttraumatic stress disorder
0.910 0.090 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.910 0.090 0.000
L73 Other follicular disorders
0.909 0.091 0.000
N10 Acute tubulo-interstitial nephritis
0.909 0.091 0.000
N70.9 Salpingitis and oophoritis, unspecified
0.908 0.092 0.000
H18.4 Corneal degeneration
0.908 0.092 0.000
G43 Migraine
0.908 0.092 0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)
0.907 0.093 0.000
M54.2 Cervicalgia
0.907 0.093 0.000
R49.0 Dysphonia
0.907 0.093 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.907 0.093 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.907 0.093 0.000
L08.8 Other specified local infections of skin and subcutaneous tissue
0.906 0.094 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.906 0.094 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.905 0.095 0.000
Q63 Other congenital malformations of kidney
0.905 0.095 0.000
H74.0 Tympanosclerosis
0.905 0.095 0.000
Q61.0 Congenital single renal cyst
0.905 0.095 0.000
M22 Disorders of patella
0.904 0.096 0.000
M54.4 Lumbago with sciatica
0.904 0.096 0.000
N64 Other disorders of breast
0.904 0.096 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.903 0.097 0.000
T45.0 Antiallergic and antiemetic drugs
0.902 0.098 0.000
E40-E46 Malnutrition
0.902 0.098 0.000
R25.3 Fasciculation
0.902 0.098 0.000
M24.5 Contracture of joint
0.901 0.099 0.000
R26.3 Immobility
0.901 0.099 0.000
S50-S59 Injuries to the elbow and forearm
0.901 0.099 0.000
G82.1 Spastic paraplegia
0.901 0.099 0.000
G70-G73 Diseases of myoneural junction and muscle
0.900 0.100 0.000
M40-M43 Deforming dorsopathies
0.900 0.100 0.000
T92.0 Sequelae of open wound of upper limb
0.900 0.100 0.000
M13.0 Polyarthritis, unspecified
0.900 0.100 0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere
0.899 0.101 0.000
G54 Nerve root and plexus disorders
0.899 0.101 0.000
G90 Disorders of autonomic nervous system
0.899 0.101 0.000
C65 Malignant neoplasm of renal pelvis
0.898 0.101 0.000
O43 Placental disorders
0.898 0.102 0.000
G83 Other paralytic syndromes
0.898 0.102 0.000
M10 Gout
0.898 0.102 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.898 0.102 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.897 0.103 0.000
E29.1 Testicular hypofunction
0.897 0.103 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.897 0.103 0.000
J30 Vasomotor and allergic rhinitis
0.897 0.103 0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified
0.897 0.103 0.000
K70-K77 Diseases of liver
0.897 0.103 0.000
S60.9 Superficial injury of wrist and hand, unspecified
0.896 0.104 0.000
S20 Superficial injury of thorax
0.896 0.104 0.000
O75.7 Vaginal delivery following previous Caesarean section
0.896 0.104 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.896 0.104 0.000
M80 Osteoporosis with pathological fracture
0.895 0.105 0.000
R94 Abnormal results of function studies
0.895 0.105 0.000
E73 Lactose intolerance
0.895 0.105 0.000
E80.4 Gilbert's syndrome
0.895 0.105 0.000
D03 Melanoma in situ
0.895 0.105 0.000
S72.30 Fracture of shaft of femur (closed)
0.895 0.105 0.000
M24.11 Other articular cartilage disorders (Shoulder region)
0.895 0.105 0.000
Chapter XXI Factors influencing health status and contact with health services
0.894 0.106 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.894 0.106 0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)
0.894 0.106 0.000
J09-J18 Influenza and pneumonia
0.894 0.106 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.894 0.106 0.000
M00-M03 Infectious arthropathies
0.894 0.106 0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs
0.894 0.106 0.000
M25.7 Osteophyte
0.894 0.106 0.000
N76.2 Acute vulvitis
0.893 0.107 0.000
R23.1 Pallor
0.893 0.107 0.000
G58.9 Mononeuropathy, unspecified
0.893 0.107 0.000
L50 Urticaria
0.893 0.107 0.000
H54 Blindness and low vision
0.893 0.107 0.000
F43.0 Acute stress reaction
0.892 0.108 0.000
N39.8 Other specified disorders of urinary system
0.892 0.108 0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
0.892 0.108 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.892 0.108 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.892 0.108 0.000
Q05 Spina bifida
0.891 0.108 0.000
T79.3 Post-traumatic wound infection, not elsewhere classified
0.891 0.109 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.891 0.109 0.000
N73 Other female pelvic inflammatory diseases
0.891 0.109 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.890 0.110 0.000
H31 Other disorders of choroid
0.890 0.110 0.000
T87.4 Infection of amputation stump
0.890 0.110 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.890 0.110 0.000
M48.02 Spinal stenosis (Cervical region)
0.890 0.110 0.000
N39.9 Disorder of urinary system, unspecified
0.889 0.111 0.000
S79.9 Unspecified injury of hip and thigh
0.889 0.111 0.000
T91 Sequelae of injuries of neck and trunk
0.889 0.111 0.000
G40 Epilepsy
0.889 0.111 0.000
M24.27 Disorder of ligament (Ankle and foot)
0.889 0.111 0.000
T00-T07 Injuries involving multiple body regions
0.888 0.112 0.000
F60 Specific personality disorders
0.888 0.112 0.000
M51.9 Intervertebral disk disorder, unspecified
0.888 0.112 0.000
G93.4 Encephalopathy, unspecified
0.888 0.112 0.000
W22.9 Unspecified place
0.888 0.112 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.887 0.113 0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)
0.887 0.113 0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)
0.887 0.113 0.000
M19.01 Primary arthrosis of other joints (Shoulder region)
0.886 0.114 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.886 0.114 0.000
G95 Other diseases of spinal cord
0.886 0.114 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.886 0.114 0.000
L40 Psoriasis
0.886 0.114 0.000
K10 Other diseases of jaws
0.885 0.115 0.000
G93.0 Cerebral cysts
0.884 0.115 0.000
M77.0 Medial epicondylitis
0.884 0.116 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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