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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs16966833
log Bayes Factor = 11.2571
Chromosome 17   position 30,035,727  (GRCh37) Explore rs16966833 on Ensembl!
Variant rs16966833 is part of Cluster X0275

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
0.999 0.001 0.000
M50-M54 Other dorsopathies
0.999 0.001 0.000
N30-N39 Other diseases of urinary system
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.995 0.005 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.993 0.007 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.992 0.008 0.000
M45-M49 Spondylopathies
0.987 0.013 0.000
M51 Other intervertebral disk disorders
0.987 0.013 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.981 0.019 0.000
N25-N29 Other disorders of kidney and ureter
0.976 0.024 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.975 0.025 0.000
N39 Other disorders of urinary system
0.973 0.027 0.000
N00-N08 Glomerular diseases
0.972 0.028 0.000
N93 Other abnormal uterine and vaginal bleeding
0.971 0.029 0.000
M47 Spondylosis
0.971 0.029 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.965 0.035 0.000
E65-E68 Obesity and other hyperalimentation
0.964 0.036 0.000
N93.0 Postcoital and contact bleeding
0.963 0.037 0.000
M51.2 Other specified intervertebral disk displacement
0.961 0.039 0.000
M50 Cervical disk disorders
0.959 0.041 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.957 0.043 0.000
N39.0 Urinary tract infection, site not specified
0.954 0.046 0.000
M20-M25 Other joint disorders
0.953 0.047 0.000
E20-E35 Disorders of other endocrine glands
0.949 0.051 0.000
G20-G26 Extrapyramidal and movement disorders
0.949 0.051 0.000
E66 Obesity
0.942 0.058 0.000
M47.8 Other spondylosis
0.937 0.063 0.000
N28.1 Cyst of kidney, acquired
0.937 0.063 0.000
N95 Menopausal and other perimenopausal disorders
0.936 0.064 0.000
N32 Other disorders of bladder
0.935 0.065 0.000
N03 Chronic nephritic syndrome
0.933 0.067 0.000
E66.9 Obesity, unspecified
0.931 0.069 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.925 0.075 0.000
N32.8 Other specified disorders of bladder
0.920 0.080 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.916 0.084 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.916 0.084 0.000
N10-N16 Renal tubulo-interstitial diseases
0.909 0.091 0.000
N40-N51 Diseases of male genital organs
0.907 0.093 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.906 0.094 0.000
Chapter X Diseases of the respiratory system
0.904 0.096 0.000
N03.9 Unspecified
0.904 0.096 0.000
M34 Systemic sclerosis
0.904 0.096 0.000
Chapter IX Diseases of the circulatory system
0.902 0.098 0.000
N95.0 Postmenopausal bleeding
0.902 0.098 0.000
E70-E90 Metabolic disorders
0.901 0.099 0.000
M47.82 Other spondylosis (Cervical region)
0.900 0.100 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.899 0.101 0.000
M50.0 Cervical disk disorder with myelopathy
0.897 0.103 0.000
Chapter VII Diseases of the eye and adnexa
0.897 0.103 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.894 0.106 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.893 0.107 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.890 0.110 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.890 0.110 0.000
M47.9 Spondylosis, unspecified
0.887 0.113 0.000
N93.9 Abnormal uterine and vaginal bleeding, unspecified
0.886 0.114 0.000
L57.0 Actinic keratosis
0.886 0.114 0.000
E86 Volume depletion
0.883 0.117 0.000
N94.8 Other specified conditions associated with female genital organs and menstrual cycle
0.882 0.118 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.880 0.120 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.878 0.122 0.000
N89 Other noninflammatory disorders of vagina
0.877 0.123 0.000
M51.8 Other specified intervertebral disk disorders
0.871 0.129 0.000
T81 Complications of procedures, not elsewhere classified
0.870 0.130 0.000
G25 Other extrapyramidal and movement disorders
0.866 0.134 0.000
G56 Mononeuropathies of upper limb
0.862 0.138 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.861 0.139 0.000
G58 Other mononeuropathies
0.858 0.142 0.000
J30-J39 Other diseases of upper respiratory tract
0.857 0.143 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.857 0.143 0.000
N41 Inflammatory diseases of prostate
0.853 0.147 0.000
N30 Cystitis
0.848 0.152 0.000
E27 Other disorders of adrenal gland
0.847 0.153 0.000
M21 Other acquired deformities of limbs
0.845 0.155 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.844 0.156 0.000
M54 Dorsalgia
0.843 0.157 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.841 0.159 0.000
G20 Parkinson's disease
0.834 0.166 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.833 0.167 0.000
M50.1 Cervical disk disorder with radiculopathy
0.833 0.167 0.000
N31.8 Other neuromuscular dysfunction of bladder
0.832 0.168 0.000
M91-M94 Chondropathies
0.829 0.171 0.000
G56.2 Lesion of ulnar nerve
0.828 0.172 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.825 0.175 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.825 0.175 0.000
S40-S49 Injuries to the shoulder and upper arm
0.824 0.176 0.000
J32 Chronic sinusitis
0.820 0.180 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.820 0.180 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.817 0.183 0.000
N50 Other disorders of male genital organs
0.816 0.184 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.811 0.189 0.000
N97 Female infertility
0.811 0.189 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.810 0.190 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.809 0.191 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.803 0.197 0.000
T66-T78 Other and unspecified effects of external causes
0.802 0.197 0.000
M47.86 Other spondylosis (Lumbar region)
0.802 0.198 0.000
M40-M43 Deforming dorsopathies
0.798 0.202 0.000
H52 Disorders of refraction and accommodation
0.797 0.203 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.797 0.203 0.000
M45 Ankylosing spondylitis
0.795 0.205 0.000
G51 Facial nerve disorders
0.795 0.205 0.000
N39.4 Other specified urinary incontinence
0.794 0.206 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.792 0.208 0.000
N48 Other disorders of penis
0.790 0.210 0.000
N02 Recurrent and persistent haematuria
0.788 0.212 0.000
N41.9 Inflammatory disease of prostate, unspecified
0.788 0.212 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.785 0.215 0.000
I95 Hypotension
0.785 0.215 0.000
N39.8 Other specified disorders of urinary system
0.784 0.216 0.000
M50.2 Other cervical disk displacement
0.784 0.216 0.000
J39 Other diseases of upper respiratory tract
0.783 0.217 0.000
T79-T79 Certain early complications of trauma
0.782 0.217 0.000
J95-J99 Other diseases of the respiratory system
0.780 0.219 0.000
M34.9 Systemic sclerosis, unspecified
0.780 0.220 0.000
N50.1 Vascular disorders of male genital organs
0.778 0.222 0.000
N83.1 Corpus luteum cyst
0.778 0.222 0.000
G90-G99 Other disorders of the nervous system
0.777 0.222 0.000
H55-H59 Other disorders of eye and adnexa
0.777 0.223 0.000
E28 Ovarian dysfunction
0.773 0.227 0.000
M34.1 CR(E)ST syndrome
0.773 0.227 0.000
S10-S19 Injuries to the neck
0.772 0.228 0.000
N83.0 Follicular cyst of ovary
0.772 0.228 0.000
S80-S89 Injuries to the knee and lower leg
0.771 0.229 0.000
M24 Other specific joint derangements
0.770 0.230 0.000
M46 Other inflammatory spondylopathies
0.769 0.231 0.000
E26 Hyperaldosteronism
0.769 0.231 0.000
M60-M63 Disorders of muscles
0.766 0.234 0.000
N13 Obstructive and reflux uropathy
0.766 0.234 0.000
M00-M03 Infectious arthropathies
0.765 0.235 0.000
I77 Other disorders of arteries and arterioles
0.765 0.235 0.000
S90-S99 Injuries to the ankle and foot
0.765 0.235 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.764 0.236 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.763 0.237 0.000
G30-G32 Other degenerative diseases of the nervous system
0.761 0.239 0.000
M34.8 Other forms of systemic sclerosis
0.760 0.240 0.000
T93 Sequelae of injuries of lower limb
0.760 0.240 0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified
0.756 0.244 0.000
E34 Other endocrine disorders
0.755 0.245 0.000
G58.9 Mononeuropathy, unspecified
0.754 0.246 0.000
I30-I52 Other forms of heart disease
0.753 0.247 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.752 0.248 0.000
M51.9 Intervertebral disk disorder, unspecified
0.750 0.250 0.000
E73 Lactose intolerance
0.748 0.252 0.000
M65-M68 Disorders of synovium and tendon
0.746 0.254 0.000
J32.9 Chronic sinusitis, unspecified
0.746 0.254 0.000
I70 Atherosclerosis
0.745 0.255 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.744 0.256 0.000
M35 Other systemic involvement of connective tissue
0.741 0.258 0.000
N95.8 Other specified menopausal and perimenopausal disorders
0.741 0.259 0.000
G54 Nerve root and plexus disorders
0.740 0.260 0.000
H52.1 Myopia
0.740 0.260 0.000
J90-J94 Other diseases of pleura
0.739 0.261 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.738 0.261 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.738 0.262 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.736 0.264 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.736 0.264 0.000
N41.1 Chronic prostatitis
0.736 0.264 0.000
N36 Other disorders of urethra
0.736 0.264 0.000
I95.9 Hypotension, unspecified
0.735 0.265 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.734 0.266 0.000
N89.8 Other specified noninflammatory disorders of vagina
0.734 0.266 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.732 0.268 0.000
Chapter VIII Diseases of the ear and mastoid process
0.732 0.268 0.000
N94.1 Dyspareunia
0.732 0.268 0.000
N94.4 Primary dysmenorrhoea
0.730 0.270 0.000
N82 Fistulae involving female genital tract
0.730 0.270 0.000
N89.6 Tight hymenal ring
0.727 0.272 0.000
M53 Other dorsopathies, not elsewhere classified
0.727 0.273 0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.726 0.274 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.724 0.276 0.000
N26 Unspecified contracted kidney
0.724 0.276 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.722 0.278 0.000
M54.9 Dorsalgia, unspecified
0.719 0.281 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.718 0.282 0.000
N04 Nephrotic syndrome
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.716 0.284 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.716 0.284 0.000
N37 Urethral disorders in diseases classified elsewhere
0.716 0.284 0.000
N34 Urethritis and urethral syndrome
0.716 0.284 0.000
N33 Bladder disorders in diseases classified elsewhere
0.716 0.284 0.000
J35 Chronic diseases of tonsils and adenoids
0.716 0.284 0.000
J39.2 Other diseases of pharynx
0.716 0.284 0.000
I60-I69 Cerebrovascular diseases
0.715 0.285 0.000
H30-H36 Disorders of choroid and retina
0.715 0.285 0.000
G35 Multiple sclerosis
0.715 0.285 0.000
T92 Sequelae of injuries of upper limb
0.713 0.287 0.000
G52 Disorders of other cranial nerves
0.712 0.288 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.712 0.288 0.000
G83 Other paralytic syndromes
0.711 0.288 0.000
T33-T35 Frostbite
0.711 0.289 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.711 0.289 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.711 0.289 0.000
T00-T07 Injuries involving multiple body regions
0.711 0.289 0.000
Q50-Q56 Congenital malformations of genital organs
0.710 0.290 0.000
T90 Sequelae of injuries of head
0.709 0.291 0.000
Q60-Q64 Congenital malformations of the urinary system
0.709 0.291 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.709 0.291 0.000
M49 Spondylopathies in diseases classified elsewhere
0.708 0.292 0.000
N05 Unspecified nephritic syndrome
0.707 0.292 0.000
M51.3 Other specified intervertebral disk degeneration
0.707 0.293 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.707 0.293 0.000
M51.4 Schmorl's nodes
0.707 0.293 0.000
N98 Complications associated with artificial fertilisation
0.703 0.297 0.000
N91 Absent, scanty and rare menstruation
0.703 0.297 0.000
N96 Habitual aborter
0.703 0.297 0.000
S70-S79 Injuries to the hip and thigh
0.701 0.299 0.000
N10 Acute tubulo-interstitial nephritis
0.701 0.299 0.000
I72 Other aneurysm
0.700 0.300 0.000
M86-M90 Other osteopathies
0.700 0.300 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.700 0.300 0.000
N27 Small kidney of unknown cause
0.700 0.300 0.000
N25 Disorders resulting from impaired renal tubular function
0.700 0.300 0.000
T87 Complications peculiar to reattachment and amputation
0.699 0.301 0.000
M94 Other disorders of cartilage
0.699 0.301 0.000
N39.2 Orthostatic proteinuria, unspecified
0.698 0.302 0.000
N39.1 Persistent proteinuria, unspecified
0.698 0.302 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.698 0.302 0.000
S50-S59 Injuries to the elbow and forearm
0.697 0.303 0.000
G82 Paraplegia and tetraplegia
0.697 0.303 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.697 0.303 0.000
N06 Isolated proteinuria with specified morphological lesion
0.697 0.303 0.000
N01 Rapidly progressive nephritic syndrome
0.697 0.303 0.000
N00 Acute nephritic syndrome
0.697 0.303 0.000
M25 Other joint disorders, not elsewhere classified
0.697 0.303 0.000
M47.1 Other spondylosis with myelopathy
0.696 0.303 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.696 0.303 0.000
J60-J70 Lung diseases due to external agents
0.696 0.304 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.696 0.304 0.000
T18 Foreign body in alimentary tract
0.695 0.305 0.000
S82 Fracture of lower leg, including ankle
0.694 0.306 0.000
H53-H54 Visual disturbances and blindness
0.694 0.306 0.000
E40-E46 Malnutrition
0.693 0.307 0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified
0.692 0.308 0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere
0.692 0.308 0.000
G55.0 Nerve root and plexus compressions in neoplastic disease
0.692 0.308 0.000
M54.3 Sciatica
0.692 0.308 0.000
E67 Other hyperalimentation
0.691 0.309 0.000
E68 Sequelae of hyperalimentation
0.691 0.309 0.000
E65 Localised adiposity
0.691 0.309 0.000
N30.9 Cystitis, unspecified
0.691 0.309 0.000
M48 Other spondylopathies
0.691 0.309 0.000
N83.3 Acquired atrophy of ovary and Fallopian tube
0.690 0.310 0.000
J91 Pleural effusion in conditions classified elsewhere
0.689 0.311 0.000
J00-J06 Acute upper respiratory infections
0.688 0.311 0.000
I63 Cerebral infarction
0.688 0.312 0.000
N32.1 Vesicointestinal fistula
0.688 0.312 0.000
M50.9 Cervical disk disorder, unspecified
0.688 0.312 0.000
M50.8 Other cervical disk disorders
0.688 0.312 0.000
G70-G73 Diseases of myoneural junction and muscle
0.688 0.312 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.687 0.312 0.000
E88 Other metabolic disorders
0.687 0.313 0.000
J98 Other respiratory disorders
0.687 0.313 0.000
N28.0 Ischaemia and infarction of kidney
0.686 0.314 0.000
E27.1 Primary adrenocortical insufficiency
0.685 0.315 0.000
G62 Other polyneuropathies
0.685 0.315 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.684 0.316 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.683 0.317 0.000
M33 Dermatopolymyositis
0.683 0.317 0.000
M32 Systemic lupus erythematosus
0.683 0.317 0.000
M30 Polyarteritis nodosa and related conditions
0.683 0.317 0.000
O85-O92 Complications predominantly related to the puerperium
0.683 0.317 0.000
S42 Fracture of shoulder and upper arm
0.683 0.317 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.683 0.317 0.000
I74 Arterial embolism and thrombosis
0.682 0.318 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.681 0.319 0.000
E32 Diseases of thymus
0.681 0.319 0.000
E31 Polyglandular dysfunction
0.681 0.319 0.000
E30 Disorders of puberty, not elsewhere classified
0.681 0.319 0.000
E25 Adrenogenital disorders
0.681 0.319 0.000
E24 Cushing's syndrome
0.681 0.319 0.000
E20 Hypoparathyroidism
0.681 0.319 0.000
I51 Complications and ill-defined descriptions of heart disease
0.681 0.319 0.000
G23 Other degenerative diseases of basal ganglia
0.680 0.319 0.000
G21 Secondary Parkinsonism
0.680 0.319 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.680 0.319 0.000
G22 Parkinsonism in diseases classified elsewhere
0.680 0.319 0.000
G50 Disorders of trigeminal nerve
0.679 0.321 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.678 0.322 0.000
M15-M19 Arthrosis
0.678 0.322 0.000
G24 Dystonia
0.678 0.322 0.000
N60-N64 Disorders of breast
0.677 0.322 0.000
J32.8 Other chronic sinusitis
0.677 0.323 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.677 0.323 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.675 0.324 0.000
E66.1 Drug-induced obesity
0.675 0.324 0.000
E66.0 Obesity due to excess calories
0.675 0.324 0.000
M47.2 Other spondylosis with radiculopathy
0.675 0.325 0.000
T85.2 Mechanical complication of intraocular lens
0.675 0.325 0.000
J32.1 Chronic frontal sinusitis
0.673 0.327 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.673 0.327 0.000
M47.89 Other spondylosis (Site unspecified)
0.672 0.328 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.672 0.328 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.672 0.328 0.000
M47.84 Other spondylosis (Thoracic region)
0.672 0.328 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.672 0.328 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.672 0.328 0.000
M21.4 Flat foot [pes planus] (acquired)
0.672 0.328 0.000
I31 Other diseases of pericardium
0.671 0.329 0.000
N95.9 Menopausal and perimenopausal disorder, unspecified
0.671 0.329 0.000
N95.3 States associated with artificial menopause
0.671 0.329 0.000
N95.1 Menopausal and female climacteric states
0.671 0.329 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.671 0.329 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.671 0.329 0.000
N32.4 Rupture of bladder, nontraumatic
0.671 0.329 0.000
N32.2 Vesical fistula, not elsewhere classified
0.671 0.329 0.000
N30.1 Interstitial cystitis (chronic)
0.670 0.329 0.000
Q00-Q07 Congenital malformations of the nervous system
0.670 0.330 0.000
E22 Hyperfunction of pituitary gland
0.669 0.330 0.000
T93.2 Sequelae of other fractures of lower limb
0.669 0.331 0.000
N03.8 Other
0.669 0.331 0.000
N03.7 Diffuse crescentic glomerulonephritis
0.669 0.331 0.000
N03.6 Dense deposit disease
0.669 0.331 0.000
N03.5 Diffuse mesangiocapillary glomerulonephritis
0.669 0.331 0.000
N03.4 Diffuse endocapillary proliferative glomerulonephritis
0.669 0.331 0.000
N03.3 Diffuse mesangial proliferative glomerulonephritis
0.669 0.331 0.000
N03.2 Diffuse membranous glomerulonephritis
0.669 0.331 0.000
N03.1 Focal and segmental glomerular lesions
0.669 0.331 0.000
N03.0 Minor glomerular abnormality
0.669 0.331 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.668 0.332 0.000
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified
0.668 0.332 0.000
G53.0 Postzoster neuralgia
0.667 0.333 0.000
H52.3 Anisometropia and aniseikonia
0.667 0.333 0.000
G25.0 Essential tremor
0.667 0.333 0.000
E27.9 Disorder of adrenal gland, unspecified
0.666 0.334 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.665 0.335 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.665 0.335 0.000
N97.1 Female infertility of tubal origin
0.664 0.336 0.000
M43 Other deforming dorsopathies
0.664 0.336 0.000
N31.1 Reflex neuropathic bladder, not elsewhere classified
0.663 0.337 0.000
N31.0 Uninhibited neuropathic bladder, not elsewhere classified
0.663 0.337 0.000
J35.0 Chronic tonsillitis
0.661 0.339 0.000
N89.5 Stricture and atresia of vagina
0.660 0.340 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.660 0.340 0.000
E83 Disorders of mineral metabolism
0.660 0.340 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.658 0.342 0.000
M21.2 Flexion deformity
0.658 0.342 0.000
H57 Other disorders of eye and adnexa
0.657 0.342 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.657 0.343 0.000
T86 Failure and rejection of transplanted organs and tissues
0.657 0.343 0.000
N94.5 Secondary dysmenorrhoea
0.657 0.343 0.000
N94.2 Vaginismus
0.657 0.343 0.000
N94.0 Mittelschmerz
0.657 0.343 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.656 0.343 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.656 0.343 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.656 0.343 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.656 0.343 0.000
S40 Superficial injury of shoulder and upper arm
0.655 0.345 0.000
E29 Testicular dysfunction
0.654 0.345 0.000
E10-E14 Diabetes mellitus
0.653 0.347 0.000
I05-I09 Chronic rheumatic heart diseases
0.652 0.348 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.652 0.348 0.000
N15 Other renal tubulo-interstitial diseases
0.652 0.348 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.652 0.348 0.000
N11 Chronic tubulo-interstitial nephritis
0.652 0.348 0.000
E27.8 Other specified disorders of adrenal gland
0.651 0.349 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.650 0.350 0.000
N46 Male infertility
0.650 0.350 0.000
N44 Torsion of testis
0.650 0.350 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.650 0.350 0.000
Q80-Q89 Other congenital malformations
0.650 0.350 0.000
Q35-Q37 Cleft lip and cleft palate
0.650 0.350 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.650 0.350 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.650 0.350 0.000
Chapter XXII Codes for special purposes
0.649 0.351 0.000
M22 Disorders of patella
0.648 0.352 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.648 0.352 0.000
M34.0 Progressive systemic sclerosis
0.648 0.352 0.000
M21.1 Varus deformity, not elsewhere classified
0.647 0.353 0.000
E28.2 Polycystic ovarian syndrome
0.647 0.353 0.000
I45 Other conduction disorders
0.647 0.353 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.647 0.353 0.000
N99-N99 Other disorders of the genitourinary system
0.647 0.353 0.000
I00-I02 Acute rheumatic fever
0.646 0.353 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.646 0.353 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.646 0.354 0.000
I77.1 Stricture of artery
0.646 0.354 0.000
E85 Amyloidosis
0.646 0.354 0.000
E84 Cystic fibrosis
0.646 0.354 0.000
E79 Disorders of purine and pyrimidine metabolism
0.646 0.354 0.000
E77 Disorders of glycoprotein metabolism
0.646 0.354 0.000
E76 Disorders of glycosaminoglycan metabolism
0.646 0.354 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.646 0.354 0.000
E74 Other disorders of carbohydrate metabolism
0.646 0.354 0.000
E72 Other disorders of amino-acid metabolism
0.646 0.354 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.646 0.354 0.000
E70 Disorders of aromatic amino-acid metabolism
0.646 0.354 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.646 0.354 0.000
H10-H13 Disorders of conjunctiva
0.645 0.354 0.000
H55 Nystagmus and other irregular eye movements
0.645 0.355 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.645 0.355 0.000
L10-L14 Bullous disorders
0.644 0.356 0.000
N48.6 Balanitis xerotica obliterans
0.643 0.357 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.643 0.357 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.643 0.357 0.000
T98 Sequelae of other and unspecified effects of external causes
0.641 0.359 0.000
T95 Sequelae of burns, corrosions and frostbite
0.641 0.359 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.641 0.359 0.000
T91 Sequelae of injuries of neck and trunk
0.641 0.359 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.641 0.359 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.641 0.359 0.000
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.640 0.360 0.000
L58 Radiodermatitis
0.640 0.360 0.000
L56 Other acute skin changes due to ultraviolet radiation
0.640 0.360 0.000
L55 Sunburn
0.640 0.360 0.000
M21.0 Valgus deformity, not elsewhere classified
0.640 0.360 0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.640 0.360 0.000
T68 Hypothermia
0.639 0.361 0.000
E26.0 Primary hyperaldosteronism
0.639 0.361 0.000
E73.9 Lactose intolerance, unspecified
0.638 0.362 0.000
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.638 0.362 0.000
L57.5 Actinic granuloma
0.638 0.362 0.000
L57.4 Cutis laxa senilis
0.638 0.362 0.000
L57.3 Poikiloderma of Civatte
0.638 0.362 0.000
L57.2 Cutis rhomboidalis nuchae
0.638 0.362 0.000
L57.1 Actinic reticuloid
0.638 0.362 0.000
N94.3 Premenstrual tension syndrome
0.637 0.362 0.000
M19 Other arthrosis
0.637 0.363 0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)
0.636 0.364 0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)
0.636 0.364 0.000
M47.94 Spondylosis, unspecified (Thoracic region)
0.636 0.364 0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)
0.636 0.364 0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)
0.636 0.364 0.000
I95.1 Orthostatic hypotension
0.636 0.364 0.000
N30.8 Other cystitis
0.635 0.365 0.000
E16 Other disorders of pancreatic internal secretion
0.635 0.365 0.000
M21.6 Other acquired deformities of ankle and foot
0.633 0.367 0.000
G58.8 Other specified mononeuropathies
0.633 0.367 0.000
I50 Heart failure
0.633 0.367 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.632 0.367 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.632 0.368 0.000
H52.2 Astigmatism
0.632 0.368 0.000
N87 Dysplasia of cervix uteri
0.631 0.368 0.000
N83.7 Haematoma of broad ligament
0.631 0.369 0.000
N83.6 Haematosalpinx
0.631 0.369 0.000
N83.5 Torsion of ovary, ovarian pedicle and Fallopian tube
0.631 0.369 0.000
N83.4 Prolapse and hernia of ovary and Fallopian tube
0.631 0.369 0.000
S20-S29 Injuries to the thorax
0.631 0.369 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.630 0.369 0.000
N13.6 Pyonephrosis
0.630 0.370 0.000
M23 Internal derangement of knee
0.630 0.370 0.000
M21.3 Wrist or foot drop (acquired)
0.630 0.370 0.000
I78 Diseases of capillaries
0.629 0.371 0.000
N89.9 Noninflammatory disorder of vagina, unspecified
0.628 0.371 0.000
N89.7 Haematocolpos
0.628 0.371 0.000
N89.4 Leukoplakia of vagina
0.628 0.371 0.000
N89.3 Dysplasia of vagina, unspecified
0.628 0.371 0.000
N89.2 Severe vaginal dysplasia, not elsewhere classified
0.628 0.371 0.000
N89.1 Moderate vaginal dysplasia
0.628 0.371 0.000
N89.0 Mild vaginal dysplasia
0.628 0.371 0.000
M67 Other disorders of synovium and tendon
0.627 0.373 0.000
H50 Other strabismus
0.627 0.373 0.000
J09-J18 Influenza and pneumonia
0.627 0.373 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.627 0.373 0.000
E23 Hypofunction and other disorders of pituitary gland
0.626 0.373 0.000
N94.9 Unspecified condition associated with female genital organs and menstrual cycle
0.626 0.373 0.000
T81.9 Unspecified complication of procedure
0.626 0.374 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.624 0.376 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.624 0.376 0.000
E50-E64 Other nutritional deficiencies
0.622 0.378 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.622 0.378 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.621 0.379 0.000
G25.9 Extrapyramidal and movement disorder, unspecified
0.621 0.379 0.000
G25.6 Drug-induced tics and other tics of organic origin
0.621 0.379 0.000
G25.5 Other chorea
0.621 0.379 0.000
G25.4 Drug-induced chorea
0.621 0.379 0.000
G25.3 Myoclonus
0.621 0.379 0.000
G25.2 Other specified forms of tremor
0.621 0.379 0.000
G25.1 Drug-induced tremor
0.621 0.379 0.000
G51.0 Bell's palsy
0.620 0.380 0.000
N02.9 Unspecified
0.620 0.380 0.000
I63.9 Cerebral infarction, unspecified
0.620 0.380 0.000
M54.2 Cervicalgia
0.619 0.381 0.000
N97.9 Female infertility, unspecified
0.619 0.381 0.000
N28.8 Other specified disorders of kidney and ureter
0.618 0.382 0.000
G56.9 Mononeuropathy of upper limb, unspecified
0.618 0.382 0.000
G56.8 Other mononeuropathies of upper limb
0.618 0.382 0.000
G56.4 Causalgia
0.618 0.382 0.000
G56.3 Lesion of radial nerve
0.618 0.382 0.000
G56.1 Other lesions of median nerve
0.618 0.382 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.617 0.383 0.000
H35 Other retinal disorders
0.617 0.383 0.000
E34.0 Carcinoid syndrome
0.616 0.384 0.000
G58.7 Mononeuritis multiplex
0.615 0.385 0.000
G58.0 Intercostal neuropathy
0.615 0.385 0.000
N30.3 Trigonitis
0.615 0.385 0.000
J37 Chronic laryngitis and laryngotracheitis
0.614 0.385 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.614 0.386 0.000
J98.8 Other specified respiratory disorders
0.614 0.386 0.000
Q76 Congenital malformations of spine and bony thorax
0.614 0.386 0.000
T78 Adverse effects, not elsewhere classified
0.614 0.386 0.000
N48.1 Balanoposthitis
0.613 0.387 0.000
N35 Urethral stricture
0.613 0.387 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.613 0.387 0.000
N02.8 Other
0.613 0.387 0.000
N48.4 Impotence of organic origin
0.613 0.387 0.000
I73 Other peripheral vascular diseases
0.613 0.387 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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