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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117803469
log Bayes Factor = 12.5069
Chromosome 20   position 1,600,405  (GRCh37) Explore rs117803469 on Ensembl!
Variant rs117803469 is part of Cluster X0275

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
1.000 0.000 0.000
M20-M25 Other joint disorders
0.999 0.001 0.000
E70-E90 Metabolic disorders
0.999 0.001 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.997 0.003 0.000
E86 Volume depletion
0.997 0.003 0.000
Chapter XIV Diseases of the genitourinary system
0.994 0.006 0.000
M13 Other arthritis
0.993 0.007 0.000
N30-N39 Other diseases of urinary system
0.992 0.008 0.000
T81 Complications of procedures, not elsewhere classified
0.990 0.010 0.000
M13.9 Arthritis, unspecified
0.986 0.014 0.000
Chapter VII Diseases of the eye and adnexa
0.986 0.014 0.000
M45-M49 Spondylopathies
0.984 0.016 0.000
M20 Acquired deformities of fingers and toes
0.983 0.017 0.000
Chapter XX External causes of morbidity and mortality
0.981 0.019 0.000
N35 Urethral stricture
0.981 0.019 0.000
N35.9 Urethral stricture, unspecified
0.973 0.027 0.000
M06 Other rheumatoid arthritis
0.970 0.030 0.000
M20.4 Other hammer toe(s) (acquired)
0.962 0.038 0.000
N10-N16 Renal tubulo-interstitial diseases
0.956 0.044 0.000
M15-M19 Arthrosis
0.953 0.047 0.000
M20.1 Hallux valgus (acquired)
0.952 0.048 0.000
S80-S89 Injuries to the knee and lower leg
0.952 0.048 0.000
N36 Other disorders of urethra
0.950 0.050 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.944 0.056 0.000
H30-H36 Disorders of choroid and retina
0.943 0.057 0.000
N13 Obstructive and reflux uropathy
0.936 0.064 0.000
M06.9 Rheumatoid arthritis, unspecified
0.934 0.066 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.932 0.068 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.929 0.071 0.000
W00-W19 Falls
0.928 0.072 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.928 0.072 0.000
M19 Other arthrosis
0.926 0.074 0.000
E20-E35 Disorders of other endocrine glands
0.924 0.076 0.000
M24 Other specific joint derangements
0.920 0.080 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.918 0.082 0.000
M50-M54 Other dorsopathies
0.917 0.083 0.000
E87.6 Hypokalaemia
0.914 0.086 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.914 0.086 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.912 0.088 0.000
H35 Other retinal disorders
0.912 0.088 0.000
S82 Fracture of lower leg, including ankle
0.910 0.090 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.898 0.102 0.000
M86-M90 Other osteopathies
0.896 0.104 0.000
E10-E14 Diabetes mellitus
0.890 0.110 0.000
M47 Spondylosis
0.890 0.110 0.000
M19.9 Arthrosis, unspecified
0.889 0.111 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.888 0.112 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.885 0.115 0.000
N36.8 Other specified disorders of urethra
0.883 0.117 0.000
M25 Other joint disorders, not elsewhere classified
0.879 0.121 0.000
T87 Complications peculiar to reattachment and amputation
0.876 0.124 0.000
M80-M85 Disorders of bone density and structure
0.873 0.127 0.000
S82.8 Fractures of other parts of lower leg
0.873 0.127 0.000
N99-N99 Other disorders of the genitourinary system
0.871 0.129 0.000
H35.3 Degeneration of macula and posterior pole
0.870 0.130 0.000
M10 Gout
0.869 0.131 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.869 0.131 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.864 0.136 0.000
M48 Other spondylopathies
0.863 0.137 0.000
N39 Other disorders of urinary system
0.862 0.138 0.000
H25-H28 Disorders of lens
0.858 0.142 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.857 0.143 0.000
Chapter VI Diseases of the nervous system
0.856 0.144 0.000
S00-S09 Injuries to the head
0.855 0.145 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.853 0.147 0.000
T00-T07 Injuries involving multiple body regions
0.852 0.148 0.000
W19 Unspecified fall
0.851 0.149 0.000
M45 Ankylosing spondylitis
0.850 0.150 0.000
M35 Other systemic involvement of connective tissue
0.847 0.153 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.847 0.153 0.000
S82.80 Fractures of other parts of lower leg (closed)
0.846 0.154 0.000
M21 Other acquired deformities of limbs
0.844 0.156 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.843 0.157 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.835 0.165 0.000
H43-H45 Disorders of vitreous body and globe
0.835 0.165 0.000
W20-W49 Exposure to inanimate mechanical forces
0.833 0.167 0.000
M05 Seropositive rheumatoid arthritis
0.832 0.168 0.000
S60-S69 Injuries to the wrist and hand
0.832 0.168 0.000
Chapter VIII Diseases of the ear and mastoid process
0.829 0.171 0.000
M50 Cervical disk disorders
0.824 0.176 0.000
N39.9 Disorder of urinary system, unspecified
0.819 0.181 0.000
S82.2 Fracture of shaft of tibia
0.819 0.181 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.818 0.182 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.817 0.183 0.000
M46 Other inflammatory spondylopathies
0.813 0.187 0.000
N36.2 Urethral caruncle
0.809 0.191 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.809 0.191 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.808 0.192 0.000
M13.93 Arthritis, unspecified (Forearm)
0.806 0.194 0.000
M91-M94 Chondropathies
0.804 0.196 0.000
M65-M68 Disorders of synovium and tendon
0.803 0.197 0.000
M19.97 Arthrosis, unspecified (Ankle and foot)
0.801 0.199 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.800 0.200 0.000
N00-N08 Glomerular diseases
0.796 0.204 0.000
W19.9 Unspecified place
0.795 0.205 0.000
S90-S99 Injuries to the ankle and foot
0.795 0.205 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.793 0.207 0.000
E85 Amyloidosis
0.792 0.208 0.000
G90-G99 Other disorders of the nervous system
0.792 0.208 0.000
E11 Non-insulin-dependent diabetes mellitus
0.792 0.208 0.000
M47.9 Spondylosis, unspecified
0.791 0.209 0.000
H10-H13 Disorders of conjunctiva
0.790 0.210 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.790 0.210 0.000
M13.0 Polyarthritis, unspecified
0.789 0.211 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.787 0.213 0.000
H36 Retinal disorders in diseases classified elsewhere
0.785 0.215 0.000
N10 Acute tubulo-interstitial nephritis
0.783 0.216 0.000
M19.0 Primary arthrosis of other joints
0.783 0.217 0.000
M31 Other necrotising vasculopathies
0.783 0.217 0.000
T86 Failure and rejection of transplanted organs and tissues
0.783 0.217 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.782 0.218 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.779 0.221 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.779 0.221 0.000
M13.94 Arthritis, unspecified (Hand)
0.778 0.222 0.000
S40-S49 Injuries to the shoulder and upper arm
0.777 0.223 0.000
S80 Superficial injury of lower leg
0.777 0.223 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.776 0.224 0.000
M10.9 Gout, unspecified
0.775 0.225 0.000
H35.8 Other specified retinal disorders
0.771 0.229 0.000
M35.0 Sicca syndrome [Sjogren]
0.771 0.229 0.000
S01 Open wound of head
0.765 0.235 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.765 0.235 0.000
M48.0 Spinal stenosis
0.764 0.236 0.000
Y40 Systemic antibiotics
0.764 0.236 0.000
M25.8 Other specified joint disorders
0.764 0.236 0.000
N13.3 Other and unspecified hydronephrosis
0.763 0.237 0.000
M06.3 Rheumatoid nodule
0.762 0.238 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.760 0.240 0.000
E88 Other metabolic disorders
0.759 0.241 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.757 0.243 0.000
M51 Other intervertebral disk disorders
0.757 0.243 0.000
M06.0 Seronegative rheumatoid arthritis
0.757 0.243 0.000
M34 Systemic sclerosis
0.756 0.244 0.000
S82.20 Fracture of shaft of tibia (closed)
0.754 0.246 0.000
E24 Cushing's syndrome
0.751 0.249 0.000
M16 Coxarthrosis [arthrosis of hip]
0.750 0.250 0.000
W06 Fall involving bed
0.749 0.251 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.748 0.252 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.747 0.253 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.747 0.253 0.000
S62 Fracture at wrist and hand level
0.745 0.255 0.000
M24.2 Disorder of ligament
0.745 0.255 0.000
E27 Other disorders of adrenal gland
0.742 0.258 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.741 0.259 0.000
M25.5 Pain in joint
0.741 0.259 0.000
H25 Senile cataract
0.741 0.259 0.000
M81 Osteoporosis without pathological fracture
0.740 0.260 0.000
X60-X84 Intentional self-harm
0.739 0.260 0.000
H80-H83 Diseases of inner ear
0.737 0.263 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.737 0.263 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.737 0.263 0.000
M07 Psoriatic and enteropathic arthropathies
0.735 0.264 0.000
E40-E46 Malnutrition
0.735 0.265 0.000
T87.4 Infection of amputation stump
0.734 0.266 0.000
Chapter XXII Codes for special purposes
0.734 0.266 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.733 0.267 0.000
M89 Other disorders of bone
0.732 0.268 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.731 0.269 0.000
E16 Other disorders of pancreatic internal secretion
0.730 0.269 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.730 0.270 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.730 0.270 0.000
H55-H59 Other disorders of eye and adnexa
0.729 0.271 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.726 0.273 0.000
M00-M03 Infectious arthropathies
0.725 0.275 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.724 0.276 0.000
N32 Other disorders of bladder
0.724 0.276 0.000
T87.6 Other and unspecified complications of amputation stump
0.724 0.276 0.000
V10-V19 Pedal cyclist injured in transport accident
0.723 0.277 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.723 0.277 0.000
V80-V89 Other land transport accidents
0.722 0.278 0.000
M24.1 Other articular cartilage disorders
0.722 0.278 0.000
M50.2 Other cervical disk displacement
0.721 0.279 0.000
M48.06 Spinal stenosis (Lumbar region)
0.721 0.279 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.720 0.280 0.000
S06 Intracranial injury
0.720 0.280 0.000
S89 Other and unspecified injuries of lower leg
0.718 0.282 0.000
N36.0 Urethral fistula
0.717 0.283 0.000
T42.4 Benzodiazepines
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
M14 Arthropathies in other diseases classified elsewhere
0.717 0.283 0.000
M12 Other specific arthropathies
0.717 0.283 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.717 0.283 0.000
M08 Juvenile arthritis
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.716 0.284 0.000
M33 Dermatopolymyositis
0.716 0.284 0.000
M32 Systemic lupus erythematosus
0.716 0.284 0.000
M30 Polyarteritis nodosa and related conditions
0.716 0.284 0.000
E84 Cystic fibrosis
0.716 0.284 0.000
E79 Disorders of purine and pyrimidine metabolism
0.716 0.284 0.000
E77 Disorders of glycoprotein metabolism
0.716 0.284 0.000
E76 Disorders of glycosaminoglycan metabolism
0.716 0.284 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.716 0.284 0.000
E74 Other disorders of carbohydrate metabolism
0.716 0.284 0.000
E73 Lactose intolerance
0.716 0.284 0.000
E72 Other disorders of amino-acid metabolism
0.716 0.284 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.716 0.284 0.000
E70 Disorders of aromatic amino-acid metabolism
0.716 0.284 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.716 0.284 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.716 0.284 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.716 0.284 0.000
E87.7 Fluid overload
0.716 0.284 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.714 0.286 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.712 0.288 0.000
N76 Other inflammation of vagina and vulva
0.712 0.288 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.712 0.288 0.000
M13.8 Other specified arthritis
0.712 0.288 0.000
M13.1 Monoarthritis, not elsewhere classified
0.712 0.288 0.000
M40-M43 Deforming dorsopathies
0.712 0.288 0.000
M21.1 Varus deformity, not elsewhere classified
0.711 0.289 0.000
N37 Urethral disorders in diseases classified elsewhere
0.711 0.289 0.000
N34 Urethritis and urethral syndrome
0.711 0.289 0.000
N33 Bladder disorders in diseases classified elsewhere
0.711 0.289 0.000
E87.2 Acidosis
0.711 0.289 0.000
T81.9 Unspecified complication of procedure
0.710 0.290 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.710 0.290 0.000
T00 Superficial injuries involving multiple body regions
0.709 0.291 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.709 0.291 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.708 0.292 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.708 0.292 0.000
M87 Osteonecrosis
0.708 0.292 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.707 0.293 0.000
N30 Cystitis
0.707 0.293 0.000
V20-V29 Motorcycle rider injured in transport accident
0.706 0.294 0.000
S01.0 Open wound of scalp
0.705 0.295 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.705 0.295 0.000
M49 Spondylopathies in diseases classified elsewhere
0.705 0.295 0.000
M65 Synovitis and tenosynovitis
0.705 0.295 0.000
N71 Inflammatory disease of uterus, except cervix
0.704 0.295 0.000
W22 Striking against or struck by other objects
0.704 0.296 0.000
Y35-Y36 Legal intervention and operations of war
0.704 0.296 0.000
Y10-Y34 Event of undetermined intent
0.704 0.296 0.000
Y00-Y09 Assault
0.704 0.296 0.000
X85-X99 Assault
0.704 0.296 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.704 0.296 0.000
X50-X57 Overexertion, travel and privation
0.704 0.296 0.000
X30-X39 Exposure to forces of nature
0.704 0.296 0.000
X20-X29 Contact with venomous animals and plants
0.704 0.296 0.000
X10-X19 Contact with heat and hot substances
0.704 0.296 0.000
X00-X09 Exposure to smoke, fire and flames
0.704 0.296 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.704 0.296 0.000
W75-W84 Other accidental threats to breathing
0.704 0.296 0.000
W65-W74 Accidental drowning and submersion
0.704 0.296 0.000
W50-W64 Exposure to animate mechanical forces
0.704 0.296 0.000
V98-V99 Other and unspecified transport accidents
0.704 0.296 0.000
V95-V97 Air and space transport accidents
0.704 0.296 0.000
V90-V94 Water transport accidents
0.704 0.296 0.000
V70-V79 Bus occupant injured in transport accident
0.704 0.296 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.704 0.296 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.704 0.296 0.000
V40-V49 Car occupant injured in transport accident
0.704 0.296 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.704 0.296 0.000
V01-V09 Pedestrian injured in transport accident
0.704 0.296 0.000
N35.8 Other urethral stricture
0.703 0.297 0.000
N35.1 Postinfective urethral stricture, not elsewhere classified
0.703 0.297 0.000
N35.0 Posttraumatic urethral stricture
0.703 0.297 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.703 0.297 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.702 0.298 0.000
M24.5 Contracture of joint
0.702 0.298 0.000
E87.5 Hyperkalaemia
0.701 0.299 0.000
M90 Osteopathies in diseases classified elsewhere
0.700 0.300 0.000
M86 Osteomyelitis
0.699 0.301 0.000
Y44 Agents primarily affecting blood constituents
0.699 0.301 0.000
M47.8 Other spondylosis
0.699 0.301 0.000
E23 Hypofunction and other disorders of pituitary gland
0.699 0.301 0.000
E87.3 Alkalosis
0.696 0.303 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.696 0.304 0.000
M16.1 Other primary coxarthrosis
0.696 0.304 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.695 0.304 0.000
H16 Keratitis
0.695 0.304 0.000
M06.8 Other specified rheumatoid arthritis
0.695 0.305 0.000
M06.4 Inflammatory polyarthropathy
0.695 0.305 0.000
M06.2 Rheumatoid bursitis
0.695 0.305 0.000
M06.1 Adult-onset Still's disease
0.695 0.305 0.000
N32.0 Bladder-neck obstruction
0.695 0.305 0.000
W08 Fall involving other furniture
0.695 0.305 0.000
M19.04 Primary arthrosis of other joints (Hand)
0.693 0.307 0.000
H35.7 Separation of retinal layers
0.693 0.307 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.693 0.307 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.691 0.309 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.691 0.309 0.000
Y43 Primarily systemic agents
0.691 0.309 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.690 0.310 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.690 0.310 0.000
M23 Internal derangement of knee
0.688 0.312 0.000
E21.3 Hyperparathyroidism, unspecified
0.688 0.312 0.000
H35.9 Retinal disorder, unspecified
0.688 0.312 0.000
H44 Disorders of globe
0.686 0.314 0.000
T79-T79 Certain early complications of trauma
0.686 0.314 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.685 0.314 0.000
N15 Other renal tubulo-interstitial diseases
0.685 0.314 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.685 0.314 0.000
N11 Chronic tubulo-interstitial nephritis
0.685 0.314 0.000
H25.0 Senile incipient cataract
0.685 0.315 0.000
E10 Insulin-dependent diabetes mellitus
0.685 0.315 0.000
M10.99 Gout, unspecified (Site unspecified)
0.685 0.315 0.000
M15 Polyarthrosis
0.683 0.316 0.000
G70-G73 Diseases of myoneural junction and muscle
0.683 0.317 0.000
S88 Traumatic amputation of lower leg
0.682 0.317 0.000
S87 Crushing injury of lower leg
0.682 0.317 0.000
S86 Injury of muscle and tendon at lower leg level
0.682 0.317 0.000
S85 Injury of blood vessels at lower leg level
0.682 0.317 0.000
S84 Injury of nerves at lower leg level
0.682 0.317 0.000
E11.5 With peripheral circulatory complications
0.682 0.318 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.681 0.319 0.000
N36.9 Urethral disorder, unspecified
0.681 0.319 0.000
N36.3 Prolapsed urethral mucosa
0.681 0.319 0.000
N36.1 Urethral diverticulum
0.681 0.319 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.680 0.320 0.000
M54 Dorsalgia
0.679 0.321 0.000
W18 Other fall on same level
0.678 0.322 0.000
E87.4 Mixed disorder of acid-base balance
0.677 0.323 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.677 0.323 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.677 0.323 0.000
H34 Retinal vascular occlusions
0.676 0.323 0.000
Y52 Agents primarily affecting the cardiovascular system
0.676 0.324 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.676 0.324 0.000
H31 Other disorders of choroid
0.676 0.324 0.000
H30 Chorioretinal inflammation
0.676 0.324 0.000
M20.3 Other deformity of hallux (acquired)
0.676 0.324 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.674 0.326 0.000
H36.0 Diabetic retinopathy
0.672 0.328 0.000
S60 Superficial injury of wrist and hand
0.672 0.328 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.672 0.328 0.000
E89.0 Postprocedural hypothyroidism
0.672 0.328 0.000
T02 Fractures involving multiple body regions
0.671 0.328 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.671 0.329 0.000
N13.6 Pyonephrosis
0.671 0.329 0.000
S01.1 Open wound of eyelid and periocular area
0.671 0.329 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.670 0.330 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.670 0.330 0.000
H35.6 Retinal haemorrhage
0.670 0.330 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.670 0.330 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.670 0.330 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.670 0.330 0.000
M18 Arthrosis of first carpometacarpal joint
0.669 0.331 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.668 0.331 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.668 0.331 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.668 0.331 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.668 0.331 0.000
M47.2 Other spondylosis with radiculopathy
0.668 0.332 0.000
N13.4 Hydroureter
0.667 0.333 0.000
W20 Struck by thrown, projected or falling object
0.666 0.333 0.000
N05 Unspecified nephritic syndrome
0.666 0.334 0.000
W17 Other fall from one level to another
0.666 0.334 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.666 0.334 0.000
W15 Fall from cliff
0.666 0.334 0.000
W14 Fall from tree
0.666 0.334 0.000
W13 Fall from, out of or through building or structure
0.666 0.334 0.000
W12 Fall on and from scaffolding
0.666 0.334 0.000
W11 Fall on and from ladder
0.666 0.334 0.000
W10 Fall on and from stairs and steps
0.666 0.334 0.000
W09 Fall involving playground equipment
0.666 0.334 0.000
W05 Fall involving wheelchair
0.666 0.334 0.000
W04 Fall while being carried or supported by other persons
0.666 0.334 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.666 0.334 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.666 0.334 0.000
W00 Fall on same level involving ice and snow
0.666 0.334 0.000
H60-H62 Diseases of external ear
0.665 0.335 0.000
N13.8 Other obstructive and reflux uropathy
0.665 0.335 0.000
H27 Other disorders of lens
0.665 0.335 0.000
T66-T78 Other and unspecified effects of external causes
0.664 0.335 0.000
Chapter V Mental and behavioural disorders
0.664 0.336 0.000
G91 Hydrocephalus
0.664 0.336 0.000
M19.8 Other specified arthrosis
0.664 0.336 0.000
M19.2 Other secondary arthrosis
0.664 0.336 0.000
M19.1 Posttraumatic arthrosis of other joints
0.664 0.336 0.000
S81 Open wound of lower leg
0.664 0.336 0.000
H43 Disorders of vitreous body
0.663 0.337 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.663 0.337 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.663 0.337 0.000
E34 Other endocrine disorders
0.663 0.337 0.000
E32 Diseases of thymus
0.663 0.337 0.000
E31 Polyglandular dysfunction
0.663 0.337 0.000
E30 Disorders of puberty, not elsewhere classified
0.663 0.337 0.000
E26 Hyperaldosteronism
0.663 0.337 0.000
E25 Adrenogenital disorders
0.663 0.337 0.000
E20 Hypoparathyroidism
0.663 0.337 0.000
W19.2 School, other institution and public administrative area
0.663 0.337 0.000
W07 Fall involving chair
0.663 0.337 0.000
S82.6 Fracture of lateral malleolus
0.662 0.338 0.000
N99.1 Postprocedural urethral stricture
0.662 0.338 0.000
S20-S29 Injuries to the thorax
0.662 0.338 0.000
W44 Foreign body entering into or through eye or natural orifice
0.660 0.340 0.000
M24.9 Joint derangement, unspecified
0.659 0.340 0.000
M24.7 Protrusio acetabuli
0.659 0.340 0.000
M24.6 Ankylosis of joint
0.659 0.340 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.659 0.340 0.000
M24.0 Loose body in joint
0.659 0.340 0.000
E28 Ovarian dysfunction
0.659 0.341 0.000
S62.6 Fracture of other finger
0.658 0.342 0.000
M25.84 Other specified joint disorders (Hand)
0.658 0.342 0.000
S80.0 Contusion of knee
0.658 0.342 0.000
M50.1 Cervical disk disorder with radiculopathy
0.656 0.344 0.000
M94 Other disorders of cartilage
0.656 0.344 0.000
M84 Disorders of continuity of bone
0.656 0.344 0.000
M82 Osteoporosis in diseases classified elsewhere
0.655 0.344 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.655 0.345 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.655 0.345 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.655 0.345 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.655 0.345 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.655 0.345 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.655 0.345 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.655 0.345 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.655 0.345 0.000
T36 Poisoning by systemic antibiotics
0.655 0.345 0.000
M21.2 Flexion deformity
0.654 0.346 0.000
N39.4 Other specified urinary incontinence
0.654 0.346 0.000
H35.5 Hereditary retinal dystrophy
0.654 0.346 0.000
H35.2 Other proliferative retinopathy
0.654 0.346 0.000
H35.1 Retinopathy of prematurity
0.654 0.346 0.000
E29 Testicular dysfunction
0.654 0.346 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.653 0.347 0.000
S82.9 Fracture of lower leg, part unspecified
0.652 0.347 0.000
S82.7 Multiple fractures of lower leg
0.652 0.347 0.000
H47.3 Other disorders of optic disk
0.652 0.348 0.000
M50.0 Cervical disk disorder with myelopathy
0.651 0.349 0.000
E21.0 Primary hyperparathyroidism
0.651 0.349 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.651 0.349 0.000
S82.0 Fracture of patella
0.651 0.349 0.000
M25.53 Pain in joint (Forearm)
0.650 0.350 0.000
E16.2 Hypoglycaemia, unspecified
0.650 0.350 0.000
G95 Other diseases of spinal cord
0.650 0.350 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.650 0.350 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.649 0.351 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.647 0.353 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.647 0.353 0.000
M80 Osteoporosis with pathological fracture
0.646 0.354 0.000
M25.7 Osteophyte
0.645 0.354 0.000
M81.9 Osteoporosis, unspecified
0.645 0.355 0.000
E27.1 Primary adrenocortical insufficiency
0.645 0.355 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.645 0.355 0.000
E85.4 Organ-limited amyloidosis
0.644 0.356 0.000
E14 Unspecified diabetes mellitus
0.643 0.357 0.000
S82.4 Fracture of fibula alone
0.640 0.360 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.640 0.360 0.000
E11.3 With ophthalmic complications
0.640 0.360 0.000
M23.3 Other meniscus derangements
0.639 0.361 0.000
E13 Other specified diabetes mellitus
0.638 0.362 0.000
E12 Malnutrition-related diabetes mellitus
0.638 0.362 0.000
H47.0 Disorders of optic nerve, not elsewhere classified
0.638 0.362 0.000
M47.1 Other spondylosis with myelopathy
0.638 0.362 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.638 0.362 0.000
S64 Injury of nerves at wrist and hand level
0.637 0.363 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.636 0.364 0.000
M88 Paget's disease of bone [osteitis deformans]
0.635 0.365 0.000
M85 Other disorders of bone density and structure
0.635 0.365 0.000
N99.0 Postprocedural renal failure
0.635 0.365 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.634 0.365 0.000
M19.98 Arthrosis, unspecified (Other)
0.633 0.367 0.000
E22 Hyperfunction of pituitary gland
0.633 0.367 0.000
E83 Disorders of mineral metabolism
0.633 0.367 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.633 0.367 0.000
M25.9 Joint disorder, unspecified
0.630 0.370 0.000
M25.3 Other instability of joint
0.630 0.370 0.000
M25.2 Flail joint
0.630 0.370 0.000
M25.1 Fistula of joint
0.630 0.370 0.000
M25.0 Haemarthrosis
0.630 0.370 0.000
S82.5 Fracture of medial malleolus
0.630 0.370 0.000
N99.5 Malfunction of external stoma of urinary tract
0.630 0.370 0.000
M19.01 Primary arthrosis of other joints (Shoulder region)
0.629 0.370 0.000
H35.4 Peripheral retinal degeneration
0.629 0.370 0.000
S05 Injury of eye and orbit
0.629 0.371 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.628 0.371 0.000
M53 Other dorsopathies, not elsewhere classified
0.628 0.372 0.000
T87.5 Necrosis of amputation stump
0.628 0.372 0.000
T87.3 Neuroma of amputation stump
0.628 0.372 0.000
T87.2 Complications of other reattached body part
0.628 0.372 0.000
T87.1 Complications of reattached (part of) lower extremity
0.628 0.372 0.000
T87.0 Complications of reattached (part of) upper extremity
0.628 0.372 0.000
M31.6 Other giant cell arteritis
0.628 0.372 0.000
E24.9 Cushing's syndrome, unspecified
0.627 0.373 0.000
M83 Adult osteomalacia
0.626 0.374 0.000
S82.86 Maisonneuve's fracture
0.626 0.374 0.000
S82.81 Fractures of other parts of lower leg (open)
0.626 0.374 0.000
M11 Other crystal arthropathies
0.625 0.375 0.000
M10.90 Gout, unspecified (Multiple sites)
0.625 0.375 0.000
H81 Disorders of vestibular function
0.625 0.375 0.000
M13.09 Polyarthritis, unspecified (Site unspecified)
0.624 0.376 0.000
N99.8 Other postprocedural disorders of genito-urinary system
0.624 0.376 0.000
H11 Other disorders of conjunctiva
0.623 0.376 0.000
M10.4 Other secondary gout
0.623 0.377 0.000
M10.3 Gout due to impairment of renal function
0.623 0.377 0.000
M10.2 Drug-induced gout
0.623 0.377 0.000
M10.1 Lead-induced gout
0.623 0.377 0.000
M10.0 Idiopathic gout
0.623 0.377 0.000
Y59 Other and unspecified vaccines and biological substances
0.623 0.377 0.000
Y58 Bacterial vaccines
0.623 0.377 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.623 0.377 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.623 0.377 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.623 0.377 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.623 0.377 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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