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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs118094226
log Bayes Factor = 14.8162
Chromosome 6   position 96,569,132  (GRCh37) Explore rs118094226 on Ensembl!
Variant rs118094226 is part of Cluster X0275

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
1.000 0.000 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
1.000 0.000 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.999 0.001 0.000
Chapter VI Diseases of the nervous system
0.997 0.003 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.996 0.004 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.993 0.007 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.988 0.012 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.984 0.016 0.000
Chapter XX External causes of morbidity and mortality
0.973 0.027 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.973 0.027 0.000
Chapter VIII Diseases of the ear and mastoid process
0.972 0.028 0.000
R30-R39 Symptoms and signs involving the urinary system
0.972 0.028 0.000
N92 Excessive, frequent and irregular menstruation
0.971 0.029 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.971 0.029 0.000
S00-S09 Injuries to the head
0.967 0.033 0.000
Chapter V Mental and behavioural disorders
0.966 0.034 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.964 0.036 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.963 0.037 0.000
N92.0 Excessive and frequent menstruation with regular cycle
0.960 0.040 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.960 0.040 0.000
N84 Polyp of female genital tract
0.951 0.049 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.949 0.051 0.000
G56 Mononeuropathies of upper limb
0.943 0.057 0.000
S70-S79 Injuries to the hip and thigh
0.934 0.066 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.929 0.071 0.000
N94.1 Dyspareunia
0.927 0.073 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.927 0.073 0.000
M70-M79 Other soft tissue disorders
0.927 0.073 0.000
N94.6 Dysmenorrhoea, unspecified
0.925 0.075 0.000
M20-M25 Other joint disorders
0.924 0.076 0.000
N30-N39 Other diseases of urinary system
0.923 0.077 0.000
R30 Pain associated with micturition
0.921 0.079 0.000
R35 Polyuria
0.920 0.080 0.000
S06 Intracranial injury
0.919 0.081 0.000
M80-M85 Disorders of bone density and structure
0.918 0.082 0.000
H65-H75 Diseases of middle ear and mastoid
0.914 0.086 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.913 0.087 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.910 0.090 0.000
G56.0 Carpal tunnel syndrome
0.909 0.091 0.000
H90-H95 Other disorders of ear
0.909 0.091 0.000
N60-N64 Disorders of breast
0.906 0.094 0.000
T79-T79 Certain early complications of trauma
0.904 0.096 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.902 0.098 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.898 0.102 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.897 0.103 0.000
N81 Female genital prolapse
0.895 0.105 0.000
T93 Sequelae of injuries of lower limb
0.893 0.107 0.000
G57 Mononeuropathies of lower limb
0.893 0.107 0.000
F30-F39 Mood [affective] disorders
0.889 0.111 0.000
S20-S29 Injuries to the thorax
0.888 0.112 0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract
0.885 0.115 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.884 0.116 0.000
F01 Vascular dementia
0.883 0.117 0.000
H90 Conductive and sensorineural hearing loss
0.880 0.120 0.000
N84.0 Polyp of corpus uteri
0.878 0.122 0.000
Chapter I Certain infectious and parasitic diseases
0.876 0.124 0.000
M50-M54 Other dorsopathies
0.873 0.127 0.000
M20 Acquired deformities of fingers and toes
0.870 0.130 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.869 0.131 0.000
M79.6 Pain in limb
0.869 0.131 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.868 0.132 0.000
H65 Nonsuppurative otitis media
0.866 0.134 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.866 0.134 0.000
N10-N16 Renal tubulo-interstitial diseases
0.864 0.136 0.000
R30.0 Dysuria
0.863 0.137 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.862 0.138 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.859 0.141 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.858 0.142 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.856 0.144 0.000
F01.9 Vascular dementia, unspecified
0.851 0.149 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.847 0.152 0.000
N81.1 Cystocele
0.847 0.153 0.000
S72 Fracture of femur
0.846 0.154 0.000
G90-G99 Other disorders of the nervous system
0.846 0.154 0.000
S40-S49 Injuries to the shoulder and upper arm
0.844 0.156 0.000
M20.5 Other deformities of toe(s) (acquired)
0.844 0.156 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.836 0.164 0.000
M84 Disorders of continuity of bone
0.835 0.164 0.000
N85.8 Other specified noninflammatory disorders of uterus
0.834 0.166 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.833 0.167 0.000
O60-O75 Complications of labour and delivery
0.832 0.168 0.000
F03 Unspecified dementia
0.829 0.171 0.000
R33 Retention of urine
0.828 0.172 0.000
T93.2 Sequelae of other fractures of lower limb
0.827 0.173 0.000
G40-G47 Episodic and paroxysmal disorders
0.823 0.177 0.000
R32 Unspecified urinary incontinence
0.821 0.179 0.000
R47-R49 Symptoms and signs involving speech and voice
0.821 0.179 0.000
W00-W19 Falls
0.821 0.179 0.000
N88 Other noninflammatory disorders of cervix uteri
0.819 0.181 0.000
G57.6 Lesion of plantar nerve
0.815 0.185 0.000
M00-M03 Infectious arthropathies
0.814 0.186 0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.812 0.188 0.000
T66-T78 Other and unspecified effects of external causes
0.812 0.188 0.000
N00-N08 Glomerular diseases
0.811 0.189 0.000
N73 Other female pelvic inflammatory diseases
0.808 0.192 0.000
N13 Obstructive and reflux uropathy
0.807 0.193 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.806 0.194 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.801 0.199 0.000
S80-S89 Injuries to the knee and lower leg
0.801 0.199 0.000
N84.1 Polyp of cervix uteri
0.800 0.200 0.000
R50-R69 General symptoms and signs
0.798 0.202 0.000
B95-B98 Bacterial, viral and other infectious agents
0.795 0.205 0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs
0.793 0.207 0.000
N60 Benign mammary dysplasia
0.793 0.207 0.000
N30 Cystitis
0.793 0.207 0.000
N99-N99 Other disorders of the genitourinary system
0.793 0.207 0.000
T90 Sequelae of injuries of head
0.792 0.208 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.792 0.208 0.000
G20-G26 Extrapyramidal and movement disorders
0.792 0.208 0.000
H65.3 Chronic mucoid otitis media
0.791 0.209 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.791 0.209 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.788 0.212 0.000
S02 Fracture of skull and facial bones
0.788 0.212 0.000
T79.3 Post-traumatic wound infection, not elsewhere classified
0.787 0.213 0.000
N81.5 Vaginal enterocele
0.786 0.214 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.786 0.214 0.000
N85.4 Malposition of uterus
0.786 0.214 0.000
F32 Depressive episode
0.786 0.214 0.000
N94.9 Unspecified condition associated with female genital organs and menstrual cycle
0.783 0.217 0.000
N92.6 Irregular menstruation, unspecified
0.783 0.217 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.780 0.220 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.779 0.221 0.000
N36 Other disorders of urethra
0.776 0.224 0.000
G70-G73 Diseases of myoneural junction and muscle
0.776 0.224 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.776 0.224 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.776 0.224 0.000
S01 Open wound of head
0.775 0.225 0.000
Chapter VII Diseases of the eye and adnexa
0.774 0.226 0.000
E10-E14 Diabetes mellitus
0.774 0.226 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.772 0.228 0.000
M20.1 Hallux valgus (acquired)
0.771 0.229 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.771 0.229 0.000
H90.5 Sensorineural hearing loss, unspecified
0.769 0.231 0.000
F60-F69 Disorders of adult personality and behaviour
0.768 0.232 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.767 0.233 0.000
E11 Non-insulin-dependent diabetes mellitus
0.766 0.234 0.000
N73.6 Female pelvic peritoneal adhesions
0.765 0.235 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.765 0.235 0.000
T91 Sequelae of injuries of neck and trunk
0.764 0.235 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.764 0.236 0.000
G56.1 Other lesions of median nerve
0.762 0.238 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.762 0.238 0.000
S05 Injury of eye and orbit
0.760 0.240 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.760 0.240 0.000
H90.3 Sensorineural hearing loss, bilateral
0.758 0.242 0.000
R30.9 Painful micturition, unspecified
0.758 0.242 0.000
S70 Superficial injury of hip and thigh
0.758 0.242 0.000
S72.1 Pertrochanteric fracture
0.757 0.243 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.756 0.244 0.000
S06.5 Traumatic subdural haemorrhage
0.756 0.244 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.754 0.245 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.754 0.246 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.754 0.246 0.000
N84.3 Polyp of vulva
0.753 0.247 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.753 0.247 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.753 0.247 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.752 0.248 0.000
R49 Voice disturbances
0.751 0.249 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.750 0.250 0.000
N39 Other disorders of urinary system
0.749 0.251 0.000
N63 Unspecified lump in breast
0.748 0.252 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.746 0.254 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.746 0.254 0.000
S10-S19 Injuries to the neck
0.745 0.255 0.000
M25 Other joint disorders, not elsewhere classified
0.745 0.255 0.000
M79.67 Pain in limb (Ankle and foot)
0.745 0.255 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.744 0.256 0.000
R34 Anuria and oliguria
0.742 0.258 0.000
E11.9 Without complications
0.742 0.258 0.000
R61 Hyperhidrosis
0.741 0.259 0.000
Y83.4 Other reconstructive surgery
0.741 0.259 0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
0.740 0.260 0.000
G54 Nerve root and plexus disorders
0.740 0.260 0.000
S06.3 Focal brain injury
0.739 0.261 0.000
N32 Other disorders of bladder
0.738 0.262 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.737 0.263 0.000
Y86 Sequelae of other accidents
0.735 0.265 0.000
M54 Dorsalgia
0.735 0.265 0.000
R23 Other skin changes
0.735 0.265 0.000
S60-S69 Injuries to the wrist and hand
0.734 0.266 0.000
F32.9 Depressive episode, unspecified
0.733 0.267 0.000
M79.0 Rheumatism, unspecified
0.733 0.267 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.732 0.268 0.000
N87 Dysplasia of cervix uteri
0.732 0.268 0.000
S90-S99 Injuries to the ankle and foot
0.731 0.269 0.000
Y85 Sequelae of transport accidents
0.730 0.270 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.730 0.270 0.000
S00 Superficial injury of head
0.729 0.271 0.000
M79.1 Myalgia
0.727 0.273 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.726 0.274 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.724 0.276 0.000
S79 Other and unspecified injuries of hip and thigh
0.723 0.277 0.000
T93.0 Sequelae of open wound of lower limb
0.723 0.277 0.000
F99-F99 Unspecified mental disorder
0.721 0.279 0.000
M24 Other specific joint derangements
0.720 0.280 0.000
M21 Other acquired deformities of limbs
0.720 0.280 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.718 0.282 0.000
N30.2 Other chronic cystitis
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M65-M68 Disorders of synovium and tendon
0.717 0.283 0.000
S27 Injury of other and unspecified intrathoracic organs
0.717 0.283 0.000
T87 Complications peculiar to reattachment and amputation
0.717 0.283 0.000
T86 Failure and rejection of transplanted organs and tissues
0.717 0.283 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.717 0.283 0.000
F31 Bipolar affective disorder
0.717 0.283 0.000
N89 Other noninflammatory disorders of vagina
0.716 0.283 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.716 0.284 0.000
H72 Perforation of tympanic membrane
0.716 0.284 0.000
N98 Complications associated with artificial fertilisation
0.716 0.284 0.000
N91 Absent, scanty and rare menstruation
0.716 0.284 0.000
N82 Fistulae involving female genital tract
0.716 0.284 0.000
N96 Habitual aborter
0.716 0.284 0.000
N71 Inflammatory disease of uterus, except cervix
0.715 0.285 0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system
0.715 0.285 0.000
M60-M63 Disorders of muscles
0.714 0.286 0.000
G30-G32 Other degenerative diseases of the nervous system
0.714 0.286 0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.713 0.287 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.712 0.288 0.000
B25-B34 Other viral diseases
0.712 0.288 0.000
S06.0 Concussion
0.712 0.288 0.000
N86 Erosion and ectropion of cervix uteri
0.711 0.289 0.000
M81 Osteoporosis without pathological fracture
0.711 0.289 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.710 0.290 0.000
M45-M49 Spondylopathies
0.710 0.290 0.000
F80-F89 Disorders of psychological development
0.709 0.291 0.000
N88.9 Noninflammatory disorder of cervix uteri, unspecified
0.709 0.291 0.000
M91-M94 Chondropathies
0.709 0.291 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.708 0.291 0.000
G52 Disorders of other cranial nerves
0.708 0.291 0.000
X60-X84 Intentional self-harm
0.708 0.292 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.708 0.292 0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures
0.708 0.292 0.000
O66 Other obstructed labour
0.707 0.293 0.000
N94.5 Secondary dysmenorrhoea
0.705 0.295 0.000
N94.4 Primary dysmenorrhoea
0.705 0.295 0.000
N94.2 Vaginismus
0.705 0.295 0.000
N94.0 Mittelschmerz
0.705 0.295 0.000
S40 Superficial injury of shoulder and upper arm
0.705 0.295 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.705 0.295 0.000
W20-W49 Exposure to inanimate mechanical forces
0.705 0.295 0.000
G50 Disorders of trigeminal nerve
0.704 0.295 0.000
H66 Suppurative and unspecified otitis media
0.704 0.296 0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
0.704 0.296 0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
0.703 0.297 0.000
R49.0 Dysphonia
0.701 0.299 0.000
R61.9 Hyperhidrosis, unspecified
0.701 0.299 0.000
N85.1 Endometrial adenomatous hyperplasia
0.700 0.300 0.000
Y35-Y36 Legal intervention and operations of war
0.697 0.302 0.000
Y10-Y34 Event of undetermined intent
0.697 0.302 0.000
Y00-Y09 Assault
0.697 0.302 0.000
X85-X99 Assault
0.697 0.302 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.697 0.302 0.000
X50-X57 Overexertion, travel and privation
0.697 0.302 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.697 0.302 0.000
X30-X39 Exposure to forces of nature
0.697 0.302 0.000
X20-X29 Contact with venomous animals and plants
0.697 0.302 0.000
X10-X19 Contact with heat and hot substances
0.697 0.302 0.000
X00-X09 Exposure to smoke, fire and flames
0.697 0.302 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.697 0.302 0.000
W75-W84 Other accidental threats to breathing
0.697 0.302 0.000
W65-W74 Accidental drowning and submersion
0.697 0.302 0.000
W50-W64 Exposure to animate mechanical forces
0.697 0.302 0.000
V98-V99 Other and unspecified transport accidents
0.697 0.302 0.000
V95-V97 Air and space transport accidents
0.697 0.302 0.000
V90-V94 Water transport accidents
0.697 0.302 0.000
V70-V79 Bus occupant injured in transport accident
0.697 0.302 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.697 0.302 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.697 0.302 0.000
V40-V49 Car occupant injured in transport accident
0.697 0.302 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.697 0.302 0.000
V01-V09 Pedestrian injured in transport accident
0.697 0.302 0.000
M79.8 Other specified soft tissue disorders
0.697 0.303 0.000
S06.8 Other intracranial injuries
0.697 0.303 0.000
R36 Urethral discharge
0.697 0.303 0.000
G58 Other mononeuropathies
0.697 0.303 0.000
T92 Sequelae of injuries of upper limb
0.697 0.303 0.000
N92.2 Excessive menstruation at puberty
0.696 0.304 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.696 0.304 0.000
R59 Enlarged lymph nodes
0.696 0.304 0.000
M79.63 Pain in limb (Forearm)
0.695 0.305 0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)
0.695 0.305 0.000
F33 Recurrent depressive disorder
0.695 0.305 0.000
N81.8 Other female genital prolapse
0.695 0.305 0.000
S72.10 Pertrochanteric fracture (closed)
0.694 0.306 0.000
S08 Traumatic amputation of part of head
0.694 0.306 0.000
S07 Crushing injury of head
0.694 0.306 0.000
S04 Injury of cranial nerves
0.694 0.306 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.694 0.306 0.000
V80-V89 Other land transport accidents
0.693 0.307 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.692 0.307 0.000
F70-F79 Mental retardation
0.692 0.307 0.000
M50 Cervical disk disorders
0.692 0.308 0.000
Chapter XXII Codes for special purposes
0.690 0.309 0.000
M53 Other dorsopathies, not elsewhere classified
0.690 0.310 0.000
N92.5 Other specified irregular menstruation
0.689 0.311 0.000
N25-N29 Other disorders of kidney and ureter
0.689 0.311 0.000
O00-O08 Pregnancy with abortive outcome
0.689 0.311 0.000
T98 Sequelae of other and unspecified effects of external causes
0.688 0.312 0.000
T95 Sequelae of burns, corrosions and frostbite
0.688 0.312 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.688 0.312 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.688 0.312 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.688 0.312 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.688 0.312 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.687 0.313 0.000
M79.64 Pain in limb (Hand)
0.687 0.313 0.000
N76 Other inflammation of vagina and vulva
0.687 0.313 0.000
N13.4 Hydroureter
0.687 0.313 0.000
M79.62 Pain in limb (Upper arm)
0.686 0.314 0.000
M80 Osteoporosis with pathological fracture
0.685 0.315 0.000
W13 Fall from, out of or through building or structure
0.684 0.315 0.000
G43 Migraine
0.684 0.316 0.000
M00 Pyogenic arthritis
0.684 0.316 0.000
N32.0 Bladder-neck obstruction
0.684 0.316 0.000
M22 Disorders of patella
0.684 0.316 0.000
N30.0 Acute cystitis
0.684 0.316 0.000
S01.9 Open wound of head, part unspecified
0.683 0.317 0.000
N84.9 Polyp of female genital tract, unspecified
0.681 0.318 0.000
N84.8 Polyp of other parts of female genital tract
0.681 0.318 0.000
R68 Other general symptoms and signs
0.681 0.319 0.000
S06.2 Diffuse brain injury
0.681 0.319 0.000
R93.6 Abnormal findings on diagnostic imaging of limbs
0.680 0.320 0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
0.680 0.320 0.000
H90.2 Conductive hearing loss, unspecified
0.680 0.320 0.000
N17-N19 Renal failure
0.680 0.320 0.000
H92 Otalgia and effusion of ear
0.679 0.321 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.679 0.321 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.678 0.322 0.000
N92.4 Excessive bleeding in the premenopausal period
0.678 0.322 0.000
Q60-Q64 Congenital malformations of the urinary system
0.678 0.322 0.000
G96 Other disorders of central nervous system
0.677 0.323 0.000
N62 Hypertrophy of breast
0.677 0.323 0.000
N94.3 Premenstrual tension syndrome
0.677 0.323 0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis
0.677 0.323 0.000
G56.9 Mononeuropathy of upper limb, unspecified
0.676 0.324 0.000
G56.8 Other mononeuropathies of upper limb
0.676 0.324 0.000
G56.4 Causalgia
0.676 0.324 0.000
G56.3 Lesion of radial nerve
0.676 0.324 0.000
N64 Other disorders of breast
0.675 0.325 0.000
M86-M90 Other osteopathies
0.675 0.325 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.675 0.325 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.673 0.327 0.000
T68 Hypothermia
0.673 0.327 0.000
G57.8 Other mononeuropathies of lower limb
0.672 0.328 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.671 0.329 0.000
G82 Paraplegia and tetraplegia
0.670 0.330 0.000
S78 Traumatic amputation of hip and thigh
0.670 0.330 0.000
S77 Crushing injury of hip and thigh
0.670 0.330 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.670 0.330 0.000
S75 Injury of blood vessels at hip and thigh level
0.670 0.330 0.000
S74 Injury of nerves at hip and thigh level
0.670 0.330 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.670 0.330 0.000
S71 Open wound of hip and thigh
0.670 0.330 0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)
0.670 0.330 0.000
G20 Parkinson's disease
0.669 0.331 0.000
M85 Other disorders of bone density and structure
0.668 0.331 0.000
S42 Fracture of shoulder and upper arm
0.668 0.332 0.000
N36.0 Urethral fistula
0.668 0.332 0.000
F00 Dementia in Alzheimer's disease
0.667 0.333 0.000
G59.0 Diabetic mononeuropathy
0.667 0.333 0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.666 0.334 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.666 0.334 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.666 0.334 0.000
T83.2 Mechanical complication of graft of urinary organ
0.666 0.334 0.000
S32 Fracture of lumbar spine and pelvis
0.666 0.334 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.666 0.334 0.000
Q00-Q07 Congenital malformations of the nervous system
0.665 0.335 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.665 0.335 0.000
F02 Dementia in other diseases classified elsewhere
0.665 0.335 0.000
F09 Unspecified organic or symptomatic mental disorder
0.665 0.335 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.665 0.335 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.665 0.335 0.000
M76 Enthesopathies of lower limb, excluding foot
0.664 0.335 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.664 0.335 0.000
R63 Symptoms and signs concerning food and fluid intake
0.664 0.336 0.000
N97 Female infertility
0.663 0.337 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.663 0.337 0.000
M34 Systemic sclerosis
0.663 0.337 0.000
M33 Dermatopolymyositis
0.663 0.337 0.000
M32 Systemic lupus erythematosus
0.663 0.337 0.000
M30 Polyarteritis nodosa and related conditions
0.663 0.337 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.662 0.338 0.000
N37 Urethral disorders in diseases classified elsewhere
0.662 0.338 0.000
N34 Urethritis and urethral syndrome
0.662 0.338 0.000
N33 Bladder disorders in diseases classified elsewhere
0.662 0.338 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.662 0.338 0.000
N94.8 Other specified conditions associated with female genital organs and menstrual cycle
0.662 0.338 0.000
M79.66 Pain in limb (Lower leg)
0.661 0.339 0.000
O20 Haemorrhage in early pregnancy
0.661 0.339 0.000
R30.1 Vesical tenesmus
0.660 0.340 0.000
H53-H54 Visual disturbances and blindness
0.659 0.341 0.000
S06.9 Intracranial injury, unspecified
0.659 0.341 0.000
S06.7 Intracranial injury with prolonged coma
0.659 0.341 0.000
S06.4 Epidural haemorrhage
0.659 0.341 0.000
S06.1 Traumatic cerebral oedema
0.659 0.341 0.000
M83 Adult osteomalacia
0.658 0.342 0.000
M82 Osteoporosis in diseases classified elsewhere
0.658 0.342 0.000
M15-M19 Arthrosis
0.658 0.342 0.000
R94 Abnormal results of function studies
0.657 0.342 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.657 0.343 0.000
N81.3 Complete uterovaginal prolapse
0.657 0.343 0.000
G40 Epilepsy
0.657 0.343 0.000
H69 Other disorders of Eustachian tube
0.657 0.343 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.657 0.343 0.000
W08 Fall involving other furniture
0.657 0.343 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.656 0.344 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.655 0.345 0.000
H74 Other disorders of middle ear and mastoid
0.655 0.345 0.000
H70 Mastoiditis and related conditions
0.655 0.345 0.000
H68 Eustachian salpingitis and obstruction
0.655 0.345 0.000
H67 Otitis media in diseases classified elsewhere
0.655 0.345 0.000
N85.7 Haematometra
0.655 0.345 0.000
N85.6 Intra-uterine synechiae
0.655 0.345 0.000
N85.5 Inversion of uterus
0.655 0.345 0.000
N85.3 Subinvolution of uterus
0.655 0.345 0.000
S01.0 Open wound of scalp
0.655 0.345 0.000
M71 Other bursopathies
0.654 0.346 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.654 0.346 0.000
N60.2 Fibroadenosis of breast
0.654 0.346 0.000
N39.9 Disorder of urinary system, unspecified
0.654 0.346 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.652 0.348 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.652 0.348 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.652 0.348 0.000
N92.1 Excessive and frequent menstruation with irregular cycle
0.652 0.348 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.652 0.348 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.652 0.348 0.000
O63 Long labour
0.650 0.350 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.650 0.350 0.000
G90 Disorders of autonomic nervous system
0.649 0.351 0.000
H71 Cholesteatoma of middle ear
0.649 0.351 0.000
R26 Abnormalities of gait and mobility
0.648 0.352 0.000
N60.4 Mammary duct ectasia
0.647 0.353 0.000
M79.9 Soft tissue disorder, unspecified
0.647 0.353 0.000
M79.5 Residual foreign body in soft tissue
0.647 0.353 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.647 0.353 0.000
M79.3 Panniculitis, unspecified
0.647 0.353 0.000
M79.2 Neuralgia and neuritis, unspecified
0.647 0.353 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.646 0.354 0.000
O61 Failed induction of labour
0.644 0.355 0.000
S82 Fracture of lower leg, including ankle
0.644 0.356 0.000
R20 Disturbances of skin sensation
0.644 0.356 0.000
V10-V19 Pedal cyclist injured in transport accident
0.644 0.356 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.644 0.356 0.000
O85-O92 Complications predominantly related to the puerperium
0.644 0.356 0.000
G41 Status epilepticus
0.644 0.356 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.643 0.357 0.000
N81.0 Female urethrocele
0.642 0.358 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.641 0.359 0.000
O62 Abnormalities of forces of labour
0.641 0.359 0.000
S22.0 Fracture of thoracic vertebra
0.641 0.359 0.000
V20-V29 Motorcycle rider injured in transport accident
0.640 0.359 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.640 0.359 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.640 0.359 0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb
0.640 0.359 0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb
0.640 0.359 0.000
T93.4 Sequelae of injury of nerve of lower limb
0.640 0.359 0.000
T93.1 Sequelae of fracture of femur
0.640 0.359 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.640 0.359 0.000
G57.9 Mononeuropathy of lower limb, unspecified
0.640 0.360 0.000
G57.5 Tarsal tunnel syndrome
0.640 0.360 0.000
G57.4 Lesion of medial popliteal nerve
0.640 0.360 0.000
G57.3 Lesion of lateral popliteal nerve
0.640 0.360 0.000
G57.2 Lesion of femoral nerve
0.640 0.360 0.000
G57.1 Meralgia paraesthetica
0.640 0.360 0.000
G57.0 Lesion of sciatic nerve
0.640 0.360 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.640 0.360 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.639 0.360 0.000
E11.4 With neurological complications
0.640 0.360 0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)
0.639 0.361 0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)
0.639 0.361 0.000
B15-B19 Viral hepatitis
0.639 0.361 0.000
H80-H83 Diseases of inner ear
0.638 0.362 0.000
S50-S59 Injuries to the elbow and forearm
0.638 0.362 0.000
F38 Other mood [affective] disorders
0.638 0.362 0.000
F34 Persistent mood [affective] disorders
0.638 0.362 0.000
F30 Manic episode
0.638 0.362 0.000
F39 Unspecified mood [affective] disorder
0.638 0.362 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.637 0.363 0.000
S29 Other and unspecified injuries of thorax
0.637 0.363 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.637 0.363 0.000
S26 Injury of heart
0.637 0.363 0.000
S25 Injury of blood vessels of thorax
0.637 0.363 0.000
S24 Injury of nerves and spinal cord at thorax level
0.637 0.363 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.637 0.363 0.000
S21 Open wound of thorax
0.637 0.363 0.000
T88.4 Failed or difficult intubation
0.637 0.363 0.000
N84.2 Polyp of vagina
0.637 0.363 0.000
M05-M14 Inflammatory polyarthropathies
0.636 0.363 0.000
H60-H62 Diseases of external ear
0.636 0.364 0.000
G44 Other headache syndromes
0.636 0.364 0.000
S72.0 Fracture of neck of femur
0.636 0.364 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.636 0.364 0.000
S02.4 Fracture of malar and maxillary bones
0.635 0.365 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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