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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3828790
log Bayes Factor = 425.616
Chromosome 6   position 32,635,809  (GRCh37) Explore rs3828790 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
D64.9 Anaemia, unspecified
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K51.9 Ulcerative colitis, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
K51 Ulcerative colitis
1.000 0.000 0.000
N48 Other disorders of penis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
J33.9 Nasal polyp, unspecified
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
Chapter XI Diseases of the digestive system
0.000 0.000 1.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.000 1.000
E10.4 With neurological complications
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
E14.9 Without complications
0.000 0.000 1.000
D50-D53 Nutritional anaemias
0.000 0.000 1.000
E11.3 With ophthalmic complications
0.000 0.000 1.000
N40-N51 Diseases of male genital organs
0.000 0.000 1.000
J33 Nasal polyp
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
E14.3 With ophthalmic complications
0.000 0.000 1.000
K70-K77 Diseases of liver
0.000 0.000 1.000
N47 Redundant prepuce, phimosis and paraphimosis
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.000 1.000
K90 Intestinal malabsorption
0.000 0.000 1.000
D50 Iron deficiency anaemia
0.000 0.001 0.999
C21 Malignant neoplasm of anus and anal canal
0.000 0.001 0.999
D50.9 Iron deficiency anaemia, unspecified
0.000 0.001 0.999
K75 Other inflammatory liver diseases
0.000 0.001 0.999
Chapter XIV Diseases of the genitourinary system
0.000 0.001 0.999
D00-D09 In situ neoplasms
0.000 0.001 0.999
J33.0 Polyp of nasal cavity
0.000 0.001 0.999
E20-E35 Disorders of other endocrine glands
0.000 0.001 0.999
D64 Other anaemias
0.000 0.001 0.999
Chapter II Neoplasms
0.000 0.001 0.999
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.001 0.999
K75.4 Autoimmune hepatitis
0.000 0.001 0.999
K90-K93 Other diseases of the digestive system
0.000 0.001 0.999
L90.0 Lichen sclerosus et atrophicus
0.000 0.001 0.999
C15-C26 Malignant neoplasms of digestive organs
0.000 0.001 0.999
D60-D64 Aplastic and other anaemias
0.000 0.001 0.999
N00-N08 Glomerular diseases
0.000 0.001 0.999
L90 Atrophic disorders of skin
0.000 0.001 0.999
M05-M14 Inflammatory polyarthropathies
0.000 0.001 0.999
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.001 0.999
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.001 0.999
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.002 0.998
M05 Seropositive rheumatoid arthritis
0.000 0.002 0.998
N48.6 Balanitis xerotica obliterans
0.000 0.002 0.998
H36 Retinal disorders in diseases classified elsewhere
0.000 0.002 0.998
D07 Carcinoma in situ of other and unspecified genital organs
0.000 0.002 0.998
C21.0 Anus, unspecified
0.000 0.002 0.998
E83.1 Disorders of iron metabolism
0.998 0.002 0.000
D07.1 Vulva
0.000 0.002 0.998
H30-H36 Disorders of choroid and retina
0.000 0.003 0.997
E10.5 With peripheral circulatory complications
0.000 0.004 0.996
Chapter VII Diseases of the eye and adnexa
0.000 0.004 0.996
D06 Carcinoma in situ of cervix uteri
0.000 0.005 0.995
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.005 0.995
N48.1 Balanoposthitis
0.000 0.005 0.995
L92 Granulomatous disorders of skin and subcutaneous tissue
0.000 0.006 0.994
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.006 0.994
D06.9 Cervix, unspecified
0.000 0.008 0.992
C21.1 Anal canal
0.000 0.008 0.992
N08 Glomerular disorders in diseases classified elsewhere
0.000 0.008 0.992
E27 Other disorders of adrenal gland
0.000 0.008 0.992
K51.4 Pseudopolyposis of colon
0.992 0.008 0.000
D51 Vitamin B12 deficiency anaemia
0.000 0.009 0.991
N08.3 Glomerular disorders in diabetes mellitus
0.000 0.011 0.989
H43-H45 Disorders of vitreous body and globe
0.000 0.011 0.989
E11.1 With ketoacidosis
0.000 0.011 0.989
K51.3 Ulcerative (chronic) rectosigmoiditis
0.989 0.011 0.000
N05 Unspecified nephritic syndrome
0.000 0.011 0.989
E27.1 Primary adrenocortical insufficiency
0.000 0.012 0.988
H43 Disorders of vitreous body
0.000 0.013 0.987
J45 Asthma
0.000 0.017 0.983
E10.2 With renal complications
0.000 0.020 0.980
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.020 0.980
H43.1 Vitreous haemorrhage
0.000 0.021 0.979
L92.0 Granuloma annulare
0.000 0.021 0.979
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.000 0.021 0.979
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.024 0.976
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.025 0.975
K51.2 Ulcerative (chronic) proctitis
0.974 0.026 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.026 0.974
Chapter IX Diseases of the circulatory system
0.000 0.026 0.974
K55-K64 Other diseases of intestines
0.000 0.027 0.973
I20-I25 Ischaemic heart diseases
0.000 0.028 0.972
C20 Malignant neoplasm of rectum
0.000 0.030 0.970
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.000 0.032 0.968
K60 Fissure and fistula of anal and rectal regions
0.000 0.033 0.967
J33.8 Other polyp of sinus
0.000 0.033 0.967
N48.0 Leukoplakia of penis
0.000 0.038 0.962
E10.0 With coma
0.000 0.038 0.962
K60.2 Anal fissure, unspecified
0.000 0.039 0.961
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.040 0.960
C09 Malignant neoplasm of tonsil
0.000 0.043 0.957
J40-J47 Chronic lower respiratory diseases
0.000 0.043 0.957
K51.8 Other ulcerative colitis
0.956 0.044 0.000
Chapter X Diseases of the respiratory system
0.000 0.044 0.956
E10.6 With other specified complications
0.000 0.047 0.953
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.050 0.950
L40-L45 Papulosquamous disorders
0.000 0.051 0.949
E11.5 With peripheral circulatory complications
0.000 0.051 0.949
N49.2 Inflammatory disorders of scrotum
0.000 0.052 0.948
E10.8 With unspecified complications
0.000 0.052 0.948
E21.0 Primary hyperparathyroidism
0.000 0.053 0.947
K55 Vascular disorders of intestine
0.000 0.056 0.944
I24 Other acute ischaemic heart diseases
0.000 0.057 0.943
K72 Hepatic failure, not elsewhere classified
0.000 0.057 0.943
I20 Angina pectoris
0.000 0.057 0.943
L80 Vitiligo
0.000 0.058 0.942
C09.9 Tonsil, unspecified
0.000 0.058 0.942
K73 Chronic hepatitis, not elsewhere classified
0.000 0.061 0.939
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.000 0.064 0.936
I25 Chronic ischaemic heart disease
0.000 0.066 0.934
E11.2 With renal complications
0.000 0.066 0.934
J46 Status asthmaticus
0.000 0.068 0.932
E21.3 Hyperparathyroidism, unspecified
0.000 0.068 0.932
E07 Other disorders of thyroid
0.000 0.069 0.931
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.070 0.930
K55.2 Angiodysplasia of colon
0.000 0.071 0.929
K90.9 Intestinal malabsorption, unspecified
0.000 0.071 0.929
I20.9 Angina pectoris, unspecified
0.000 0.073 0.927
E24 Cushing's syndrome
0.000 0.073 0.927
L40 Psoriasis
0.000 0.075 0.925
N04 Nephrotic syndrome
0.000 0.077 0.923
K51.5 Mucosal proctocolitis
0.922 0.078 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.081 0.919
M06.3 Rheumatoid nodule
0.000 0.081 0.919
H34 Retinal vascular occlusions
0.000 0.082 0.918
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.000 0.082 0.918
L40.9 Psoriasis, unspecified
0.000 0.083 0.917
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.083 0.917
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.083 0.917
I25.5 Ischaemic cardiomyopathy
0.000 0.083 0.917
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.090 0.910
K86 Other diseases of pancreas
0.000 0.091 0.909
E06 Thyroiditis
0.000 0.092 0.908
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.093 0.907
N05.2 Diffuse membranous glomerulonephritis
0.000 0.100 0.900
G35-G37 Demyelinating diseases of the central nervous system
0.830 0.100 0.070
E07.9 Disorder of thyroid, unspecified
0.000 0.101 0.899
Chapter VI Diseases of the nervous system
0.000 0.104 0.896
K57 Diverticular disease of intestine
0.000 0.104 0.896
E16.1 Other hypoglycaemia
0.000 0.106 0.894
K57.3 Diverticular disease of large intestine without perforation or abscess
0.000 0.107 0.893
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.000 0.108 0.892
E13 Other specified diabetes mellitus
0.000 0.109 0.891
N05.1 Focal and segmental glomerular lesions
0.000 0.111 0.889
J30-J39 Other diseases of upper respiratory tract
0.000 0.111 0.889
K86.3 Pseudocyst of pancreas
0.000 0.112 0.888
D50.8 Other iron deficiency anaemias
0.000 0.112 0.888
H43.8 Other disorders of vitreous body
0.000 0.113 0.887
K75.8 Other specified inflammatory liver diseases
0.000 0.113 0.887
K60.0 Acute anal fissure
0.000 0.114 0.886
I74 Arterial embolism and thrombosis
0.000 0.116 0.884
I10-I15 Hypertensive diseases
0.000 0.116 0.884
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.117 0.883
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.118 0.882
E03.8 Other specified hypothyroidism
0.000 0.119 0.881
N48.4 Impotence of organic origin
0.000 0.119 0.881
E11.6 With other specified complications
0.000 0.120 0.880
G63 Polyneuropathy in diseases classified elsewhere
0.000 0.121 0.879
L10-L14 Bullous disorders
0.000 0.122 0.878
H34.8 Other retinal vascular occlusions
0.000 0.122 0.878
M06.4 Inflammatory polyarthropathy
0.000 0.125 0.875
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.126 0.874
G63.2 Diabetic polyneuropathy
0.000 0.129 0.871
H43.3 Other vitreous opacities
0.000 0.132 0.868
E06.3 Autoimmune thyroiditis
0.000 0.133 0.867
D01 Carcinoma in situ of other and unspecified digestive organs
0.000 0.133 0.867
E14.8 With unspecified complications
0.000 0.136 0.864
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.137 0.863
N48.2 Other inflammatory disorders of penis
0.000 0.137 0.863
J45.0 Predominantly allergic asthma
0.000 0.138 0.862
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.139 0.861
I20.0 Unstable angina
0.000 0.139 0.861
D07.4 Penis
0.000 0.143 0.857
K72.0 Acute and subacute hepatic failure
0.000 0.144 0.856
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.145 0.855
K86.0 Alcohol-induced chronic pancreatitis
0.000 0.146 0.854
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.000 0.148 0.852
K60.1 Chronic anal fissure
0.000 0.149 0.851
C22.9 Liver, unspecified
0.000 0.149 0.851
E14.1 With ketoacidosis
0.000 0.150 0.850
E50-E64 Other nutritional deficiencies
0.000 0.151 0.849
I77 Other disorders of arteries and arterioles
0.000 0.151 0.849
K86.1 Other chronic pancreatitis
0.000 0.153 0.847
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.156 0.844
K51.0 Ulcerative (chronic) enterocolitis
0.844 0.156 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.164 0.836
N04.9 Unspecified
0.000 0.164 0.836
I10 Essential (primary) hypertension
0.000 0.166 0.834
K55.8 Other vascular disorders of intestine
0.000 0.167 0.833
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.168 0.831
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.169 0.831
N05.8 Other
0.000 0.172 0.828
J86 Pyothorax
0.000 0.177 0.823
N05.9 Unspecified
0.000 0.179 0.821
C22.1 Intrahepatic bile duct carcinoma
0.000 0.180 0.819
E14.6 With other specified complications
0.000 0.181 0.819
E53 Deficiency of other B group vitamins
0.000 0.182 0.818
I74.8 Embolism and thrombosis of other arteries
0.000 0.183 0.817
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.000 0.183 0.817
E11.0 With coma
0.000 0.185 0.815
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.187 0.813
K82 Other diseases of gallbladder
0.000 0.187 0.813
E13.9 Without complications
0.000 0.189 0.811
K74 Fibrosis and cirrhosis of liver
0.000 0.192 0.808
J95-J99 Other diseases of the respiratory system
0.000 0.193 0.807
E20 Hypoparathyroidism
0.000 0.193 0.807
C07 Malignant neoplasm of parotid gland
0.000 0.193 0.807
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.193 0.807
M14 Arthropathies in other diseases classified elsewhere
0.000 0.194 0.806
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.195 0.805
K72.9 Hepatic failure, unspecified
0.000 0.195 0.805
N48.5 Ulcer of penis
0.000 0.195 0.804
C04 Malignant neoplasm of floor of mouth
0.000 0.197 0.803
C91.1 Chronic lymphocytic leukaemia
0.000 0.199 0.801
E53.8 Deficiency of other specified B group vitamins
0.000 0.200 0.800
G00-G09 Inflammatory diseases of the central nervous system
0.000 0.202 0.798
I74.5 Embolism and thrombosis of iliac artery
0.000 0.202 0.798
G70-G73 Diseases of myoneural junction and muscle
0.000 0.204 0.796
C21.8 Overlapping lesion of rectum, anus and anal canal
0.000 0.204 0.796
E24.9 Cushing's syndrome, unspecified
0.000 0.206 0.794
G37 Other demyelinating diseases of central nervous system
0.774 0.207 0.020
H25-H28 Disorders of lens
0.000 0.207 0.793
E14.4 With neurological complications
0.000 0.209 0.791
E14.2 Withrenal complications
0.000 0.210 0.790
E24.0 Pituitary-dependent Cushing's disease
0.000 0.214 0.786
G60 Hereditary and idiopathic neuropathy
0.000 0.216 0.784
C23 Malignant neoplasm of gallbladder
0.000 0.217 0.783
D04 Carcinoma in situ of skin
0.000 0.218 0.782
L13 Other bullous disorders
0.000 0.221 0.779
J86.0 Pyothorax with fistula
0.000 0.221 0.779
E27.2 Addisonian crisis
0.000 0.221 0.779
K82.9 Disease of gallbladder, unspecified
0.000 0.223 0.777
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.226 0.774
C91 Lymphoid leukaemia
0.000 0.227 0.773
I25.2 Old myocardial infarction
0.000 0.228 0.772
D06.0 Endocervix
0.000 0.229 0.771
C12 Malignant neoplasm of pyriform sinus
0.000 0.229 0.771
K73.9 Chronic hepatitis, unspecified
0.000 0.232 0.768
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.234 0.766
K86.2 Cyst of pancreas
0.000 0.234 0.766
I77.6 Arteritis, unspecified
0.000 0.235 0.765
K82.8 Other specified diseases of gallbladder
0.000 0.237 0.763
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.244 0.756
G61 Inflammatory polyneuropathy
0.000 0.246 0.754
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.246 0.754
C11 Malignant neoplasm of nasopharynx
0.000 0.247 0.753
I73 Other peripheral vascular diseases
0.000 0.247 0.753
L94 Other localised connective tissue disorders
0.000 0.247 0.753
C10 Malignant neoplasm of oropharynx
0.000 0.247 0.753
L95 Vasculitis limited to skin, not elsewhere classified
0.000 0.248 0.752
M12 Other specific arthropathies
0.000 0.248 0.752
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.249 0.751
E05.8 Other thyrotoxicosis
0.000 0.249 0.751
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.252 0.748
N51 Disorders of male genital organs in diseases classified elsewhere
0.000 0.253 0.747
M06.8 Other specified rheumatoid arthritis
0.000 0.254 0.746
H31 Other disorders of choroid
0.000 0.256 0.744
M45-M49 Spondylopathies
0.000 0.257 0.743
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.259 0.741
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.262 0.738
C13 Malignant neoplasm of hypopharynx
0.000 0.262 0.738
G00 Bacterial meningitis, not elsewhere classified
0.000 0.263 0.737
E24.2 Drug-induced Cushing's syndrome
0.000 0.265 0.735
N04.1 Focal and segmental glomerular lesions
0.000 0.265 0.735
N48.9 Disorder of penis, unspecified
0.000 0.266 0.734
E21.2 Other hyperparathyroidism
0.000 0.267 0.733
J45.1 Nonallergic asthma
0.000 0.267 0.733
I24.8 Other forms of acute ischaemic heart disease
0.000 0.268 0.732
I73.9 Peripheral vascular disease, unspecified
0.000 0.268 0.732
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.270 0.730
G37.9 Demyelinating disease of central nervous system, unspecified
0.727 0.270 0.003
I25.1 Atherosclerotic heart disease
0.000 0.271 0.729
L40.0 Psoriasis vulgaris
0.000 0.271 0.729
C02 Malignant neoplasm of other and unspecified parts of tongue
0.000 0.272 0.728
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.274 0.726
D01.0 Colon
0.000 0.275 0.725
I22 Subsequent myocardial infarction
0.000 0.275 0.725
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.277 0.723
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.277 0.723
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.000 0.278 0.722
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.278 0.722
M05.2 Rheumatoid vasculitis
0.000 0.278 0.721
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.279 0.721
E21.4 Other specified disorders of parathyroid gland
0.000 0.280 0.720
G72 Other myopathies
0.000 0.281 0.719
L12 Pemphigoid
0.000 0.281 0.719
L40.1 Generalised pustular psoriasis
0.000 0.282 0.718
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.5 With peripheral circulatory complications
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
K77 Liver disorders in diseases classified elsewhere
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.000 0.283 0.717
L87 Transepidermal elimination disorders
0.000 0.283 0.717
L86 Keratoderma in diseases classified elsewhere
0.000 0.283 0.717
K90.3 Pancreatic steatorrhoea
0.000 0.283 0.717
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.283 0.717
K90.1 Tropical sprue
0.000 0.283 0.717
D50.1 Sideropenic dysphagia
0.000 0.283 0.717
D01.3 Anus and anal canal
0.000 0.283 0.717
C21.2 Cloacogenic zone
0.000 0.283 0.716
K75.2 Nonspecific reactive hepatitis
0.000 0.283 0.716
K75.1 Phlebitis of portal vein
0.000 0.283 0.716
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.284 0.716
E32 Diseases of thymus
0.000 0.284 0.716
E31 Polyglandular dysfunction
0.000 0.284 0.716
E30 Disorders of puberty, not elsewhere classified
0.000 0.284 0.716
D64.4 Congenital dyserythropoietic anaemia
0.000 0.284 0.716
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.284 0.716
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.284 0.716
D64.0 Hereditary sideroblastic anaemia
0.000 0.284 0.716
K71 Toxic liver disease
0.000 0.284 0.716
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.284 0.716
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.284 0.716
N07 Hereditary nephropathy, not elsewhere classified
0.000 0.284 0.716
N06 Isolated proteinuria with specified morphological lesion
0.000 0.284 0.716
N01 Rapidly progressive nephritic syndrome
0.000 0.284 0.716
N00 Acute nephritic syndrome
0.000 0.284 0.716
L90.9 Atrophic disorder of skin, unspecified
0.000 0.284 0.716
L90.6 Striae atrophicae
0.000 0.284 0.716
L90.4 Acrodermatitis chronica atrophicans
0.000 0.284 0.716
L90.3 Atrophoderma of Pasini and Pierini
0.000 0.284 0.716
L90.2 Anetoderma of Jadassohn-Pellizzari
0.000 0.284 0.716
L90.1 Anetoderma of Schweninger-Buzzi
0.000 0.284 0.716
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.284 0.716
M08 Juvenile arthritis
0.000 0.284 0.716
M14.6 Neuropathic arthropathy
0.000 0.284 0.716
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.284 0.716
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.284 0.716
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.284 0.716
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.284 0.716
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.284 0.716
M05.8 Other seropositive rheumatoid arthritis
0.000 0.284 0.716
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.284 0.716
M05.1 Rheumatoid lung disease
0.000 0.284 0.716
M05.0 Felty's syndrome
0.000 0.284 0.716
D07.6 Other and unspecified male genital organs
0.000 0.284 0.715
D07.3 Other and unspecified female genital organs
0.000 0.284 0.715
D07.0 Endometrium
0.000 0.284 0.715
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.284 0.715
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.285 0.714
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.286 0.714
D06.7 Other parts of cervix
0.000 0.286 0.714
D06.1 Exocervix
0.000 0.286 0.714
L92.2 Granuloma faciale [eosinophilic granuloma of skin]
0.000 0.287 0.713
L92.1 Necrobiosis lipoidica, not elsewhere classified
0.000 0.287 0.713
N05.7 Diffuse crescentic glomerulonephritis
0.000 0.288 0.712
D07.2 Vagina
0.000 0.288 0.712
E03.1 Congenital hypothyroidism without goitre
0.000 0.289 0.711
N08.8 Glomerular disorders in other diseases classified elsewhere
0.000 0.289 0.711
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.000 0.289 0.711
N08.1 Glomerular disorders in neoplastic diseases
0.000 0.289 0.711
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.000 0.289 0.711
E27.5 Adrenomedullary hyperfunction
0.000 0.289 0.711
E27.0 Other adrenocortical overactivity
0.000 0.289 0.711
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.289 0.711
D51.2 Transcobalamin II deficiency
0.000 0.289 0.711
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.289 0.711
H43.2 Crystalline deposits in vitreous body
0.000 0.291 0.709
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.291 0.709
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.291 0.709
N05.6 Dense deposit disease
0.000 0.291 0.709
N05.4 Diffuse endocapillary proliferative glomerulonephritis
0.000 0.291 0.709
N05.0 Minor glomerular abnormality
0.000 0.291 0.709
H30 Chorioretinal inflammation
0.000 0.291 0.709
L13.0 Dermatitis herpetiformis
0.000 0.291 0.709
N44 Torsion of testis
0.000 0.292 0.708
H26 Other cataract
0.000 0.294 0.706
M10 Gout
0.000 0.295 0.705
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess
0.000 0.295 0.705
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens
0.000 0.296 0.704
K55.1 Chronic vascular disorders of intestine
0.000 0.296 0.704
C01 Malignant neoplasm of base of tongue
0.000 0.297 0.703
I00-I02 Acute rheumatic fever
0.000 0.297 0.703
C17 Malignant neoplasm of small intestine
0.000 0.297 0.702
G50-G59 Nerve, nerve root and plexus disorders
0.000 0.298 0.702
I15 Secondary hypertension
0.000 0.299 0.701
K72.1 Chronic hepatic failure
0.000 0.299 0.701
K58 Irritable bowel syndrome
0.000 0.300 0.700
K64 Haemorrhoids and perianal venous thrombosis
0.000 0.303 0.697
H35 Other retinal disorders
0.000 0.305 0.695
H26.9 Cataract, unspecified
0.000 0.305 0.695
N49.9 Inflammatory disorder of unspecified male genital organ
0.000 0.306 0.694
N49.0 Inflammatory disorders of seminal vesicle
0.000 0.306 0.694
N04.2 Diffuse membranous glomerulonephritis
0.000 0.306 0.694
D53 Other nutritional anaemias
0.000 0.311 0.689
H43.0 Vitreous prolapse
0.000 0.311 0.689
C09.8 Overlapping lesion of tonsil
0.000 0.314 0.686
C09.1 Tonsillar pillar (anterior) (posterior)
0.000 0.314 0.686
D04.9 Skin, unspecified
0.000 0.316 0.684
K75.9 Inflammatory liver disease, unspecified
0.000 0.316 0.684
L40.4 Guttate psoriasis
0.000 0.316 0.684
M06.1 Adult-onset Still's disease
0.000 0.317 0.683
C09.0 Tonsillar fossa
0.000 0.318 0.682
M06.34 Rheumatoid nodule (Hand)
0.000 0.318 0.682
L44 Other papulosquamous disorders
0.000 0.320 0.680
L41 Parapsoriasis
0.000 0.320 0.680
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.320 0.680
G70 Myasthenia gravis and other myoneural disorders
0.000 0.321 0.679
I12 Hypertensive renal disease
0.000 0.321 0.679
I25.6 Silent myocardial ischaemia
0.000 0.321 0.678
C08 Malignant neoplasm of other and unspecified major salivary glands
0.000 0.322 0.678
C04.9 Floor of mouth, unspecified
0.000 0.323 0.677
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.000 0.324 0.676
H34.2 Other retinal artery occlusions
0.000 0.324 0.676
I77.8 Other specified disorders of arteries and arterioles
0.000 0.325 0.675
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.325 0.675
I23 Certain current complications following acute myocardial infarction
0.000 0.325 0.675
J98 Other respiratory disorders
0.000 0.325 0.675
E25 Adrenogenital disorders
0.000 0.326 0.674
C60-C63 Malignant neoplasms of male genital organs
0.000 0.326 0.674
G00.1 Pneumococcal meningitis
0.000 0.327 0.673
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.327 0.673
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.327 0.673
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.327 0.673
K60.5 Anorectal fistula
0.000 0.327 0.672
G60.0 Hereditary motor and sensory neuropathy
0.000 0.329 0.671
C22.7 Other specified carcinomas of liver
0.000 0.329 0.671
C22.4 Other sarcomas of liver
0.000 0.329 0.671
C22.3 Angiosarcoma of liver
0.000 0.329 0.671
C22.2 Hepatoblastoma
0.000 0.329 0.671
H31.0 Chorioretinal scars
0.000 0.330 0.670
E20.9 Hypoparathyroidism, unspecified
0.000 0.331 0.669
E40-E46 Malnutrition
0.000 0.331 0.668
E07.1 Dyshormogenetic goitre
0.000 0.332 0.668
E07.0 Hypersecretion of calcitonin
0.000 0.332 0.668
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.000 0.333 0.667
K51.1 Ulcerative (chronic) ileocolitis
0.665 0.335 0.000
E24.8 Other Cushing's syndrome
0.000 0.336 0.664
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.336 0.664
E24.3 Ectopic ACTH syndrome
0.000 0.336 0.664
E24.1 Nelson's syndrome
0.000 0.336 0.664
L40.3 Pustulosis palmaris et plantaris
0.000 0.336 0.663
L40.2 Acrodermatitis continua
0.000 0.336 0.663
E11.8 With unspecified complications
0.000 0.337 0.663
G72.0 Drug-induced myopathy
0.000 0.337 0.663
M11 Other crystal arthropathies
0.000 0.337 0.663
K57.4 Diverticular disease of both small and large intestine with perforation and abscess
0.000 0.337 0.663
E06.5 Other chronic thyroiditis
0.000 0.337 0.663
N04.8 Other
0.000 0.338 0.661
N04.7 Diffuse crescentic glomerulonephritis
0.000 0.338 0.661
N04.6 Dense deposit disease
0.000 0.338 0.661
N04.5 Diffuse mesangiocapillary glomerulonephritis
0.000 0.338 0.661
N04.4 Diffuse endocapillary proliferative glomerulonephritis
0.000 0.338 0.661
N04.3 Diffuse mesangial proliferative glomerulonephritis
0.000 0.338 0.661
N04.0 Minor glomerular abnormality
0.000 0.338 0.661
J45.8 Mixed asthma
0.000 0.339 0.661
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.341 0.659
M06.38 Rheumatoid nodule (Other)
0.000 0.341 0.659
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.341 0.659
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.341 0.659
M06.33 Rheumatoid nodule (Forearm)
0.000 0.341 0.659
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.341 0.659
K74.3 Primary biliary cirrhosis
0.000 0.341 0.659
H34.0 Transient retinal artery occlusion
0.000 0.341 0.658
J98.0 Diseases of bronchus, not elsewhere classified
0.000 0.342 0.658

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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