TreeWAS – Variant ID: rs9268614

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	1.000	0.000	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	1.000	0.000	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	1.000	0.000	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	1.000	0.000	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	1.000	0.000	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	1.000	0.000	0.000
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
E10.9 Without complications	1.000	0.000	0.000
E10.3 With ophthalmic complications	1.000	0.000	0.000
E10.1 With ketoacidosis	1.000	0.000	0.000
E11.9 Without complications	1.000	0.000	0.000
H36.0 Diabetic retinopathy	1.000	0.000	0.000
J33.9 Nasal polyp, unspecified	1.000	0.000	0.000
J33.0 Polyp of nasal cavity	1.000	0.000	0.000
J45.9 Asthma, unspecified	1.000	0.000	0.000
K90.0 Coeliac disease	0.000	0.000	1.000
M05.9 Seropositive rheumatoid arthritis, unspecified	1.000	0.000	0.000
M06.9 Rheumatoid arthritis, unspecified	1.000	0.000	0.000
M35.3 Polymyalgia rheumatica	1.000	0.000	0.000
E11 Non-insulin-dependent diabetes mellitus	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
G35 Multiple sclerosis	0.000	0.000	1.000
J33 Nasal polyp	1.000	0.000	0.000
M06 Other rheumatoid arthritis	1.000	0.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
J40-J47 Chronic lower respiratory diseases	1.000	0.000	0.000
J30-J39 Other diseases of upper respiratory tract	1.000	0.000	0.000
M20-M25 Other joint disorders	1.000	0.000	0.000
M05-M14 Inflammatory polyarthropathies	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
Chapter X Diseases of the respiratory system	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	1.000	0.000	0.000
M05 Seropositive rheumatoid arthritis	1.000	0.000	0.000
K57.3 Diverticular disease of large intestine without perforation or abscess	1.000	0.000	0.000
E14 Unspecified diabetes mellitus	1.000	0.000	0.000
M31 Other necrotising vasculopathies	1.000	0.000	0.000
M06.3 Rheumatoid nodule	1.000	0.000	0.000
J45 Asthma	1.000	0.000	0.000
E16.2 Hypoglycaemia, unspecified	1.000	0.000	0.000
E16 Other disorders of pancreatic internal secretion	1.000	0.000	0.000
Chapter VII Diseases of the eye and adnexa	1.000	0.000	0.000
M31.6 Other giant cell arteritis	1.000	0.000	0.000
M35 Other systemic involvement of connective tissue	1.000	0.000	0.000
M20 Acquired deformities of fingers and toes	1.000	0.000	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
E10.4 With neurological complications	1.000	0.000	0.000
E03 Other hypothyroidism	1.000	0.000	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.999	0.001	0.000
M45-M49 Spondylopathies	0.999	0.001	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.999	0.001	0.000
M45 Ankylosing spondylitis	0.998	0.002	0.000
J32 Chronic sinusitis	0.998	0.002	0.000
H36 Retinal disorders in diseases classified elsewhere	0.998	0.002	0.000
M06.34 Rheumatoid nodule (Hand)	0.998	0.002	0.000
E14.3 With ophthalmic complications	0.998	0.002	0.000
E10.5 With peripheral circulatory complications	0.998	0.002	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.998	0.002	0.000
K57 Diverticular disease of intestine	0.998	0.002	0.000
H30-H36 Disorders of choroid and retina	0.997	0.003	0.000
E11.3 With ophthalmic complications	0.997	0.003	0.000
M20.4 Other hammer toe(s) (acquired)	0.996	0.004	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.996	0.004	0.000
M06.0 Seronegative rheumatoid arthritis	0.996	0.004	0.000
K51.9 Ulcerative colitis, unspecified	0.000	0.006	0.994
M45.X9 Ankylosing spondylitis (Site unspecified)	0.994	0.006	0.000
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess	0.994	0.006	0.000
J32.9 Chronic sinusitis, unspecified	0.993	0.007	0.000
H20 Iridocyclitis	0.993	0.007	0.000
J20-J22 Other acute lower respiratory infections	0.992	0.008	0.000
E14.9 Without complications	0.991	0.009	0.000
K51 Ulcerative colitis	0.000	0.009	0.991
M65-M68 Disorders of synovium and tendon	0.989	0.011	0.000
M06.4 Inflammatory polyarthropathy	0.988	0.012	0.000
L80-L99 Other disorders of the skin and subcutaneous tissue	0.986	0.014	0.000
L40-L45 Papulosquamous disorders	0.985	0.015	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.984	0.016	0.000
J33.8 Other polyp of sinus	0.984	0.016	0.000
M65 Synovitis and tenosynovitis	0.984	0.016	0.000
L97 Ulcer of lower limb, not elsewhere classified	0.979	0.021	0.000
J22 Unspecified acute lower respiratory infection	0.979	0.021	0.000
L40 Psoriasis	0.978	0.022	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.978	0.022	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.975	0.025	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.975	0.025	0.000
K57.2 Diverticular disease of large intestine with perforation and abscess	0.972	0.028	0.000
L40.9 Psoriasis, unspecified	0.970	0.030	0.000
J46 Status asthmaticus	0.970	0.030	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.969	0.031	0.000
K51.4 Pseudopolyposis of colon	0.000	0.032	0.968
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.965	0.035	0.000
Chapter VIII Diseases of the ear and mastoid process	0.960	0.040	0.000
H20.9 Iridocyclitis, unspecified	0.957	0.043	0.000
L90 Atrophic disorders of skin	0.957	0.043	0.000
E06 Thyroiditis	0.955	0.045	0.000
L80 Vitiligo	0.953	0.047	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.952	0.048	0.000
L90.0 Lichen sclerosus et atrophicus	0.950	0.050	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.947	0.053	0.000
Chapter XX External causes of morbidity and mortality	0.946	0.054	0.000
E10.6 With other specified complications	0.942	0.058	0.000
E11.1 With ketoacidosis	0.939	0.061	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.938	0.062	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.936	0.064	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.936	0.064	0.000
H00 Hordeolum and chalazion	0.936	0.064	0.000
J42 Unspecified chronic bronchitis	0.934	0.066	0.000
H00.0 Hordeolum and other deep inflammation of eyelid	0.932	0.068	0.000
L05 Pilonidal cyst	0.929	0.071	0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.928	0.072	0.000
E10.0 With coma	0.926	0.074	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.923	0.077	0.000
E11.4 With neurological complications	0.923	0.077	0.000
L05.0 Pilonidal cyst with abscess	0.923	0.077	0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.923	0.077	0.000
H20.0 Acute and subacute iridocyclitis	0.922	0.078	0.000
M12 Other specific arthropathies	0.920	0.080	0.000
J95-J99 Other diseases of the respiratory system	0.918	0.082	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.918	0.082	0.000
M35.1 Other overlap syndromes	0.913	0.087	0.000
E14.6 With other specified complications	0.911	0.089	0.000
E10.2 With renal complications	0.910	0.090	0.000
N47 Redundant prepuce, phimosis and paraphimosis	0.909	0.091	0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.907	0.093	0.000
E10.8 With unspecified complications	0.906	0.094	0.000
H16 Keratitis	0.905	0.095	0.000
H53-H54 Visual disturbances and blindness	0.905	0.095	0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.905	0.095	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.902	0.098	0.000
K51.2 Ulcerative (chronic) proctitis	0.000	0.101	0.899
L40.0 Psoriasis vulgaris	0.899	0.101	0.000
J32.4 Chronic pansinusitis	0.898	0.102	0.000
J47 Bronchiectasis	0.896	0.104	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.896	0.104	0.000
M14 Arthropathies in other diseases classified elsewhere	0.895	0.105	0.000
M20.1 Hallux valgus (acquired)	0.893	0.107	0.000
M20.5 Other deformities of toe(s) (acquired)	0.892	0.108	0.000
M65.4 Radial styloid tenosynovitis [de Quervain]	0.889	0.111	0.000
E06.3 Autoimmune thyroiditis	0.888	0.112	0.000
L89 Decubitus ulcer	0.887	0.113	0.000
N40-N51 Diseases of male genital organs	0.887	0.113	0.000
M25 Other joint disorders, not elsewhere classified	0.885	0.115	0.000
M25.4 Effusion of joint	0.884	0.116	0.000
H54 Blindness and low vision	0.882	0.118	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.880	0.120	0.000
J44 Other chronic obstructive pulmonary disease	0.877	0.123	0.000
M25.46 Effusion of joint (Lower leg)	0.877	0.123	0.000
J99 Respiratory disorders in diseases classified elsewhere	0.877	0.123	0.000
H65-H75 Diseases of middle ear and mastoid	0.876	0.124	0.000
N48 Other disorders of penis	0.874	0.126	0.000
J43 Emphysema	0.872	0.128	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.872	0.128	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.870	0.130	0.000
Q80-Q89 Other congenital malformations	0.868	0.132	0.000
M91-M94 Chondropathies	0.863	0.137	0.000
J32.2 Chronic ethmoidal sinusitis	0.863	0.137	0.000
M05.8 Other seropositive rheumatoid arthritis	0.862	0.138	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.859	0.141	0.000
L89.1 Stage II decubitus ulcer	0.858	0.142	0.000
M31.7 Microscopic polyangiitis	0.857	0.143	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.857	0.143	0.000
M30 Polyarteritis nodosa and related conditions	0.857	0.143	0.000
M12.3 Palindromic rheumatism	0.853	0.147	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.000	0.151	0.849
K51.5 Mucosal proctocolitis	0.000	0.152	0.848
M06.30 Rheumatoid nodule (Multiple sites)	0.848	0.152	0.000
J20 Acute bronchitis	0.848	0.152	0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.845	0.155	0.000
N48.1 Balanoposthitis	0.845	0.155	0.000
J99.0 Rheumatoid lung disease	0.845	0.155	0.000
H20.8 Other iridocyclitis	0.844	0.156	0.000
H15 Disorders of sclera	0.840	0.160	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.836	0.164	0.000
V20-V29 Motorcycle rider injured in transport accident	0.836	0.164	0.000
M65.1 Other infective (teno)synovitis	0.835	0.165	0.000
M05.1 Rheumatoid lung disease	0.834	0.166	0.000
M86-M90 Other osteopathies	0.833	0.167	0.000
E11.5 With peripheral circulatory complications	0.833	0.167	0.000
M25.40 Effusion of joint (Multiple sites)	0.832	0.168	0.000
M46 Other inflammatory spondylopathies	0.830	0.170	0.000
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess	0.830	0.170	0.000
Chapter XIV Diseases of the genitourinary system	0.829	0.171	0.000
M66 Spontaneous rupture of synovium and tendon	0.828	0.172	0.000
H31 Other disorders of choroid	0.827	0.173	0.000
M49 Spondylopathies in diseases classified elsewhere	0.824	0.176	0.000
J32.0 Chronic maxillary sinusitis	0.824	0.176	0.000
X50-X57 Overexertion, travel and privation	0.817	0.183	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.817	0.183	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.000	0.184	0.816
H90-H95 Other disorders of ear	0.815	0.185	0.000
J33.1 Polypoid sinus degeneration	0.815	0.185	0.000
M06.8 Other specified rheumatoid arthritis	0.811	0.189	0.000
E11.6 With other specified complications	0.810	0.190	0.000
J00-J06 Acute upper respiratory infections	0.808	0.192	0.000
E06.5 Other chronic thyroiditis	0.808	0.192	0.000
Q83 Congenital malformations of breast	0.805	0.195	0.000
N49.2 Inflammatory disorders of scrotum	0.804	0.196	0.000
Y00-Y09 Assault	0.804	0.196	0.000
H20.1 Chronic iridocyclitis	0.804	0.196	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.804	0.196	0.000
H74 Other disorders of middle ear and mastoid	0.804	0.196	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.802	0.198	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.801	0.199	0.000
M14.6 Neuropathic arthropathy	0.800	0.200	0.000
E07 Other disorders of thyroid	0.798	0.202	0.000
H21 Other disorders of iris and ciliary body	0.798	0.202	0.000
J38.6 Stenosis of larynx	0.797	0.203	0.000
H01 Other inflammation of eyelid	0.797	0.203	0.000
J35 Chronic diseases of tonsils and adenoids	0.796	0.204	0.000
M94 Other disorders of cartilage	0.795	0.205	0.000
H16.8 Other keratitis	0.794	0.206	0.000
L20-L30 Dermatitis and eczema	0.793	0.207	0.000
N48.0 Leukoplakia of penis	0.793	0.207	0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.793	0.207	0.000
E10.7 With multiple complications	0.790	0.210	0.000
N42 Other disorders of prostate	0.789	0.211	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.788	0.212	0.000
E50-E64 Other nutritional deficiencies	0.788	0.212	0.000
H54.7 Unspecified visual loss	0.786	0.214	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.786	0.214	0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)	0.786	0.214	0.000
M08 Juvenile arthritis	0.784	0.216	0.000
K51.8 Other ulcerative colitis	0.000	0.217	0.783
L92 Granulomatous disorders of skin and subcutaneous tissue	0.781	0.219	0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.780	0.220	0.000
X60-X84 Intentional self-harm	0.777	0.223	0.000
L10-L14 Bullous disorders	0.777	0.223	0.000
J09-J18 Influenza and pneumonia	0.776	0.224	0.000
H00.1 Chalazion	0.776	0.224	0.000
H54.0 Blindness, both eyes	0.776	0.224	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.775	0.225	0.000
J95 Postprocedural respiratory disorders, not elsewhere classified	0.774	0.226	0.000
V80-V89 Other land transport accidents	0.774	0.226	0.000
M66.2 Spontaneous rupture of extensor tendons	0.772	0.228	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.771	0.229	0.000
M65.2 Calcific tendinitis	0.770	0.230	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.770	0.230	0.000
H74.4 Polyp of middle ear	0.769	0.231	0.000
H66 Suppurative and unspecified otitis media	0.767	0.233	0.000
Q28 Other congenital malformations of circulatory system	0.767	0.233	0.000
H54.1 Blindness, one eye, low vision, other eye	0.766	0.234	0.000
W50-W64 Exposure to animate mechanical forces	0.764	0.236	0.000
M20.3 Other deformity of hallux (acquired)	0.764	0.236	0.000
J21 Acute bronchiolitis	0.763	0.237	0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.762	0.237	0.000
H70 Mastoiditis and related conditions	0.762	0.238	0.000
J43.9 Emphysema, unspecified	0.761	0.239	0.000
N42.2 Atrophy of prostate	0.760	0.240	0.000
H80-H83 Diseases of inner ear	0.759	0.241	0.000
L40.8 Other psoriasis	0.759	0.241	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.759	0.241	0.000
Q89 Other congenital malformations, not elsewhere classified	0.757	0.243	0.000
H16.4 Corneal neovascularisation	0.757	0.243	0.000
E16.1 Other hypoglycaemia	0.757	0.243	0.000
L43 Lichen planus	0.757	0.243	0.000
M12.39 Palindromic rheumatism (Site unspecified)	0.756	0.244	0.000
X10-X19 Contact with heat and hot substances	0.754	0.246	0.000
L30 Other dermatitis	0.752	0.248	0.000
H31.0 Chorioretinal scars	0.751	0.249	0.000
M00-M03 Infectious arthropathies	0.748	0.252	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.746	0.254	0.000
X00-X09 Exposure to smoke, fire and flames	0.746	0.254	0.000
M94.8 Other specified disorders of cartilage	0.746	0.254	0.000
H16.0 Corneal ulcer	0.746	0.254	0.000
J32.1 Chronic frontal sinusitis	0.744	0.256	0.000
M31.3 Wegener's granulomatosis	0.744	0.256	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.742	0.258	0.000
J44.8 Other specified chronic obstructive pulmonary disease	0.742	0.258	0.000
E14.1 With ketoacidosis	0.740	0.260	0.000
E11.8 With unspecified complications	0.739	0.261	0.000
V28 Motorcycle rider injured in noncollision transport accident	0.738	0.262	0.000
M20.0 Deformity of finger(s)	0.737	0.263	0.000
W20-W49 Exposure to inanimate mechanical forces	0.737	0.263	0.000
E03.1 Congenital hypothyroidism without goitre	0.737	0.263	0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.737	0.263	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.735	0.265	0.000
V95-V97 Air and space transport accidents	0.733	0.267	0.000
M66.24 Spontaneous rupture of extensor tendons (Hand)	0.733	0.267	0.000
L05.9 Pilonidal cyst without abscess	0.732	0.268	0.000
M12.30 Palindromic rheumatism (Multiple sites)	0.731	0.269	0.000
N48.6 Balanitis xerotica obliterans	0.729	0.271	0.000
M65.14 Other infective (teno)synovitis (Hand)	0.728	0.272	0.000
Y04 Assault by bodily force	0.727	0.273	0.000
J01 Acute sinusitis	0.727	0.273	0.000
H92 Otalgia and effusion of ear	0.727	0.273	0.000
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.725	0.275	0.000
X50 Overexertion and strenuous or repetitive movements	0.725	0.275	0.000
V98-V99 Other and unspecified transport accidents	0.725	0.275	0.000
E07.9 Disorder of thyroid, unspecified	0.725	0.275	0.000
M25.43 Effusion of joint (Forearm)	0.724	0.276	0.000
J85 Abscess of lung and mediastinum	0.723	0.277	0.000
H60-H62 Diseases of external ear	0.723	0.277	0.000
E14.2 Withrenal complications	0.723	0.277	0.000
E13 Other specified diabetes mellitus	0.721	0.279	0.000
M21 Other acquired deformities of limbs	0.721	0.279	0.000
J38.7 Other diseases of larynx	0.721	0.279	0.000
J20.9 Acute bronchitis, unspecified	0.721	0.279	0.000
J95.0 Tracheostomy malfunction	0.720	0.280	0.000
H43-H45 Disorders of vitreous body and globe	0.719	0.281	0.000
X58 Exposure to other specified factors	0.719	0.281	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.718	0.282	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.717	0.283	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.717	0.283	0.000
E11.7 With multiple complications	0.717	0.283	0.000
M06.2 Rheumatoid bursitis	0.717	0.283	0.000
M06.1 Adult-onset Still's disease	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
J41 Simple and mucopurulent chronic bronchitis	0.717	0.283	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.717	0.283	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.717	0.283	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.717	0.283	0.000
M05.2 Rheumatoid vasculitis	0.717	0.283	0.000
M05.0 Felty's syndrome	0.717	0.283	0.000
E14.7 With multiple complications	0.717	0.283	0.000
E14.0 With coma	0.717	0.283	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.717	0.283	0.000
M06.38 Rheumatoid nodule (Other)	0.717	0.283	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.717	0.283	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.717	0.283	0.000
M06.33 Rheumatoid nodule (Forearm)	0.717	0.283	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.717	0.283	0.000
J45.8 Mixed asthma	0.717	0.283	0.000
M31.8 Other specified necrotising vasculopathies	0.717	0.283	0.000
M31.2 Lethal midline granuloma	0.717	0.283	0.000
M31.0 Hypersensitivity angiitis	0.717	0.283	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.717	0.283	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.717	0.283	0.000
E16.4 Abnormal secretion of gastrin	0.717	0.283	0.000
E16.3 Increased secretion of glucagon	0.717	0.283	0.000
E15 Nondiabetic hypoglycaemic coma	0.717	0.283	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.717	0.283	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.717	0.283	0.000
M35.5 Multifocal fibrosclerosis	0.717	0.283	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E03.5 Myxoedema coma	0.717	0.283	0.000
E03.4 Atrophy of thyroid (acquired)	0.717	0.283	0.000
E03.3 Postinfectious hypothyroidism	0.717	0.283	0.000
L30.9 Dermatitis, unspecified	0.717	0.283	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.716	0.284	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.716	0.284	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.716	0.284	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.716	0.284	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.716	0.284	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.716	0.284	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.716	0.284	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.716	0.284	0.000
E06.1 Subacute thyroiditis	0.715	0.284	0.000
Q35-Q37 Cleft lip and cleft palate	0.715	0.285	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.715	0.285	0.000
J86 Pyothorax	0.715	0.285	0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.715	0.285	0.000
M05.19 Rheumatoid lung disease (Site unspecified)	0.715	0.285	0.000
H16.3 Interstitial and deep keratitis	0.714	0.286	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.714	0.286	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.714	0.286	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.714	0.286	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.714	0.286	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.714	0.286	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.714	0.286	0.000
J06 Acute upper respiratory infections of multiple and unspecified sites	0.713	0.287	0.000
W75-W84 Other accidental threats to breathing	0.712	0.288	0.000
H20.2 Lens-induced iridocyclitis	0.712	0.288	0.000
M35.2 Behcet's disease	0.712	0.288	0.000
K57.4 Diverticular disease of both small and large intestine with perforation and abscess	0.710	0.290	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.709	0.291	0.000
H54.2 Low vision, both eyes	0.708	0.292	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.708	0.292	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.708	0.292	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.708	0.292	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.708	0.292	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.708	0.292	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.708	0.292	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.708	0.292	0.000
Q83.1 Accessory breast	0.707	0.293	0.000
M60-M63 Disorders of muscles	0.707	0.293	0.000
J45.0 Predominantly allergic asthma	0.707	0.293	0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.707	0.293	0.000
L87 Transepidermal elimination disorders	0.707	0.293	0.000
L86 Keratoderma in diseases classified elsewhere	0.707	0.293	0.000
L44 Other papulosquamous disorders	0.707	0.293	0.000
L41 Parapsoriasis	0.707	0.293	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.707	0.293	0.000
V01-V09 Pedestrian injured in transport accident	0.706	0.294	0.000
M65.0 Abscess of tendon sheath	0.705	0.295	0.000
H17 Corneal scars and opacities	0.705	0.295	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.705	0.295	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.705	0.295	0.000
J99.8 Respiratory disorders in other diseases classified elsewhere	0.704	0.296	0.000
H66.9 Otitis media, unspecified	0.704	0.296	0.000
N48.4 Impotence of organic origin	0.701	0.299	0.000
L40.4 Guttate psoriasis	0.701	0.299	0.000
L40.3 Pustulosis palmaris et plantaris	0.701	0.299	0.000
L40.2 Acrodermatitis continua	0.701	0.299	0.000
M12.2 Villonodular synovitis (pigmented)	0.701	0.299	0.000
Q83.8 Other congenital malformations of breast	0.700	0.300	0.000
M49.5 Collapsed vertebra in diseases classified elsewhere	0.699	0.301	0.000
M46.1 Sacro-iliitis, not elsewhere classified	0.699	0.301	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.000	0.302	0.698
J38.5 Laryngeal spasm	0.698	0.302	0.000
R31 Unspecified haematuria	0.698	0.302	0.000
M14.2 Diabetic arthropathy	0.696	0.304	0.000
M31.9 Necrotising vasculopathy, unspecified	0.696	0.304	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.696	0.304	0.000
H54.4 Blindness, one eye	0.695	0.305	0.000
K57.5 Diverticular disease of both small and large intestine without perforation or abscess	0.695	0.305	0.000
N48.5 Ulcer of penis	0.695	0.305	0.000
M35.8 Other specified systemic involvement of connective tissue	0.695	0.305	0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.694	0.306	0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.694	0.306	0.000
J32.3 Chronic sphenoidal sinusitis	0.694	0.306	0.000
M86 Osteomyelitis	0.693	0.307	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.692	0.308	0.000
H69 Other disorders of Eustachian tube	0.692	0.308	0.000
M91 Juvenile osteochondrosis of hip and pelvis	0.691	0.308	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.689	0.311	0.000
Q25 Congenital malformations of great arteries	0.687	0.313	0.000
E03.8 Other specified hypothyroidism	0.687	0.313	0.000
H15.1 Episcleritis	0.687	0.313	0.000
L90.9 Atrophic disorder of skin, unspecified	0.686	0.314	0.000
L90.8 Other atrophic disorders of skin	0.686	0.314	0.000
L90.6 Striae atrophicae	0.686	0.314	0.000
L90.4 Acrodermatitis chronica atrophicans	0.686	0.314	0.000
L90.3 Atrophoderma of Pasini and Pierini	0.686	0.314	0.000
L90.2 Anetoderma of Jadassohn-Pellizzari	0.686	0.314	0.000
L90.1 Anetoderma of Schweninger-Buzzi	0.686	0.314	0.000
J11 Influenza, virus not identified	0.685	0.315	0.000
J38.4 Oedema of larynx	0.685	0.315	0.000
L43.8 Other lichen planus	0.685	0.315	0.000
M89 Other disorders of bone	0.685	0.315	0.000
E06.4 Drug-induced thyroiditis	0.684	0.315	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.684	0.315	0.000
E06.0 Acute thyroiditis	0.684	0.315	0.000
Y10-Y34 Event of undetermined intent	0.684	0.316	0.000
E06.9 Thyroiditis, unspecified	0.682	0.318	0.000
M30.0 Polyarteritis nodosa	0.682	0.318	0.000
V90-V94 Water transport accidents	0.681	0.319	0.000
L40.1 Generalised pustular psoriasis	0.681	0.319	0.000
M94.86 Other specified disorders of cartilage (Lower leg)	0.681	0.319	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.680	0.320	0.000
M25.3 Other instability of joint	0.679	0.321	0.000
H72 Perforation of tympanic membrane	0.679	0.321	0.000
J45.1 Nonallergic asthma	0.678	0.321	0.000
Y35-Y36 Legal intervention and operations of war	0.678	0.322	0.000
X85-X99 Assault	0.678	0.322	0.000
X30-X39 Exposure to forces of nature	0.678	0.322	0.000
W65-W74 Accidental drowning and submersion	0.678	0.322	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.678	0.322	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.678	0.322	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.678	0.322	0.000
Q89.2 Congenital malformations of other endocrine glands	0.678	0.322	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.678	0.322	0.000
J38.0 Paralysis of vocal cords and larynx	0.678	0.322	0.000
M25.45 Effusion of joint (Pelvic region and thigh)	0.677	0.323	0.000
E11.0 With coma	0.676	0.324	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.675	0.324	0.000
H70.9 Mastoiditis, unspecified	0.674	0.326	0.000
N42.9 Disorder of prostate, unspecified	0.674	0.326	0.000
W44 Foreign body entering into or through eye or natural orifice	0.673	0.327	0.000
M13 Other arthritis	0.672	0.328	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.671	0.328	0.000
L00 Staphylococcal scalded skin syndrome	0.671	0.329	0.000
N49.8 Inflammatory disorders of other specified male genital organs	0.671	0.329	0.000
J43.2 Centrilobular emphysema	0.669	0.331	0.000
H01.8 Other specified inflammation of eyelid	0.669	0.331	0.000
M25.42 Effusion of joint (Upper arm)	0.668	0.332	0.000
E14.8 With unspecified complications	0.668	0.332	0.000
Q27 Other congenital malformations of peripheral vascular system	0.667	0.333	0.000
W00-W19 Falls	0.667	0.333	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.666	0.334	0.000
L12 Pemphigoid	0.665	0.335	0.000
E14.5 With peripheral circulatory complications	0.665	0.335	0.000
H15.0 Scleritis	0.664	0.336	0.000
H30 Chorioretinal inflammation	0.664	0.336	0.000
M25.8 Other specified joint disorders	0.663	0.337	0.000
M31.1 Thrombotic microangiopathy	0.663	0.337	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.662	0.338	0.000
M12.8 Other specific arthropathies, not elsewhere classified	0.660	0.340	0.000
M12.5 Traumatic arthropathy	0.660	0.340	0.000
M12.4 Intermittent hydrarthrosis	0.660	0.340	0.000
M12.1 Kaschin-Beck disease	0.660	0.340	0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.660	0.340	0.000
J96 Respiratory failure, not elsewhere classified	0.658	0.342	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.656	0.344	0.000
V70-V79 Bus occupant injured in transport accident	0.656	0.344	0.000
H91 Other hearing loss	0.655	0.345	0.000
E14.4 With neurological complications	0.655	0.345	0.000
E11.2 With renal complications	0.655	0.345	0.000
Y04.8 Other specified place	0.655	0.345	0.000
L08 Other local infections of skin and subcutaneous tissue	0.653	0.346	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.653	0.347	0.000
H80 Otosclerosis	0.652	0.348	0.000
J20.8 Acute bronchitis due to other specified organisms	0.651	0.348	0.000
J35.1 Hypertrophy of tonsils	0.650	0.350	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.650	0.350	0.000
M34 Systemic sclerosis	0.648	0.352	0.000
N51 Disorders of male genital organs in diseases classified elsewhere	0.648	0.352	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations