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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant cluster associations

Hospitalization Episode Statistics (HES)

Cluster X0259
log Bayes Factor = 246.237
contains 11 variants:
rs73147826
lBF = 14.893
Chr 3 : 116,659,269
rs79733042
lBF = 12.074
Chr 3 : 146,691,517
rs116080128
lBF = 12.196
Chr 4 : 31,457,995
rs75697640
lBF = 11.868
Chr 5 : 61,428,150
rs17406405
lBF = 16.491
Chr 7 : 78,658,711
rs76637462
lBF = 18.024
Chr 7 : 105,262,173
rs75445152
lBF = 16.265
Chr 9 : 104,310,061
rs12722598
lBF = 17.177
Chr10 : 6,055,150
rs78745584
lBF = 13.255
Chr11 : 97,029,941
rs75466358
lBF = 21.462
Chr14 : 98,107,800
rs17774983
lBF = 12.667
Chr16 : 89,493,234
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
C78 Secondary malignant neoplasm of respiratory and digestive organs
1.000 0.000 0.000
C79 Secondary malignant neoplasm of other sites
1.000 0.000 0.000
C15-C26 Malignant neoplasms of digestive organs
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
1.000 0.000 0.000
G40-G47 Episodic and paroxysmal disorders
1.000 0.000 0.000
G90-G99 Other disorders of the nervous system
1.000 0.000 0.000
H65-H75 Diseases of middle ear and mastoid
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
M70-M79 Other soft tissue disorders
1.000 0.000 0.000
N17-N19 Renal failure
1.000 0.000 0.000
O60-O75 Complications of labour and delivery
1.000 0.000 0.000
S00-S09 Injuries to the head
1.000 0.000 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
1.000 0.000 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
1.000 0.000 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
1.000 0.000 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
1.000 0.000 0.000
M25 Other joint disorders, not elsewhere classified
1.000 0.000 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
1.000 0.000 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
1.000 0.000 0.000
N18 Chronic renal failure
1.000 0.000 0.000
E70-E90 Metabolic disorders
1.000 0.000 0.000
Chapter VIII Diseases of the ear and mastoid process
1.000 0.000 0.000
M79.8 Other specified soft tissue disorders
1.000 0.000 0.000
M75 Shoulder lesions
1.000 0.000 0.000
M80-M85 Disorders of bone density and structure
1.000 0.000 0.000
A30-A49 Other bacterial diseases
1.000 0.000 0.000
N18.9 Chronic renal failure, unspecified
1.000 0.000 0.000
M79 Other soft tissue disorders, not elsewhere classified
1.000 0.000 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
1.000 0.000 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
1.000 0.000 0.000
M84 Disorders of continuity of bone
1.000 0.000 0.000
S80-S89 Injuries to the knee and lower leg
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
M24 Other specific joint derangements
1.000 0.000 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
1.000 0.000 0.000
M21 Other acquired deformities of limbs
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
1.000 0.000 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
1.000 0.000 0.000
D70-D77 Other diseases of blood and blood-forming organs
1.000 0.000 0.000
S06 Intracranial injury
1.000 0.000 0.000
S90-S99 Injuries to the ankle and foot
0.999 0.001 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.999 0.001 0.000
E87.7 Fluid overload
0.999 0.001 0.000
H72 Perforation of tympanic membrane
0.999 0.001 0.000
L89 Decubitus ulcer
0.999 0.001 0.000
S60-S69 Injuries to the wrist and hand
0.999 0.001 0.000
S70-S79 Injuries to the hip and thigh
0.999 0.001 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.999 0.001 0.000
J09-J18 Influenza and pneumonia
0.999 0.001 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.999 0.001 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.999 0.001 0.000
M86-M90 Other osteopathies
0.999 0.001 0.000
A41 Other septicaemia
0.999 0.001 0.000
M23 Internal derangement of knee
0.999 0.001 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.999 0.001 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.999 0.001 0.000
Chapter XXII Codes for special purposes
0.999 0.001 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.999 0.001 0.000
C78.7 Secondary malignant neoplasm of liver
0.999 0.001 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.998 0.002 0.000
Chapter VII Diseases of the eye and adnexa
0.998 0.002 0.000
D68 Other coagulation defects
0.998 0.002 0.000
M75.5 Bursitis of shoulder
0.998 0.002 0.000
B95-B98 Bacterial, viral and other infectious agents
0.998 0.002 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.998 0.002 0.000
M06 Other rheumatoid arthritis
0.998 0.002 0.000
W00-W19 Falls
0.998 0.002 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.998 0.002 0.000
T92 Sequelae of injuries of upper limb
0.998 0.002 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.998 0.002 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.998 0.002 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.998 0.002 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.998 0.002 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.998 0.002 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.998 0.002 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.997 0.003 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.997 0.003 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.997 0.003 0.000
S20-S29 Injuries to the thorax
0.997 0.003 0.000
C83.3 Large cell (diffuse)
0.997 0.003 0.000
N17 Acute renal failure
0.997 0.003 0.000
H74 Other disorders of middle ear and mastoid
0.997 0.003 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.997 0.003 0.000
M65-M68 Disorders of synovium and tendon
0.997 0.003 0.000
O00-O08 Pregnancy with abortive outcome
0.997 0.003 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.997 0.003 0.000
G70-G73 Diseases of myoneural junction and muscle
0.997 0.003 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.997 0.003 0.000
S70 Superficial injury of hip and thigh
0.996 0.004 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.996 0.004 0.000
T93 Sequelae of injuries of lower limb
0.996 0.004 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.996 0.004 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.996 0.004 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.995 0.005 0.000
J81 Pulmonary oedema
0.995 0.005 0.000
M75.2 Bicipital tendinitis
0.995 0.005 0.000
B35-B49 Mycoses
0.995 0.005 0.000
L89.1 Stage II decubitus ulcer
0.995 0.005 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.995 0.005 0.000
T51 Toxic effect of alcohol
0.995 0.005 0.000
N17.9 Acute renal failure, unspecified
0.995 0.005 0.000
G93 Other disorders of brain
0.995 0.005 0.000
E83 Disorders of mineral metabolism
0.994 0.006 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.994 0.006 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.994 0.006 0.000
C15 Malignant neoplasm of oesophagus
0.993 0.007 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.993 0.007 0.000
A41.9 Septicaemia, unspecified
0.993 0.007 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.993 0.007 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.993 0.007 0.000
M65 Synovitis and tenosynovitis
0.992 0.008 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.992 0.008 0.000
C78.0 Secondary malignant neoplasm of lung
0.992 0.008 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.991 0.009 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.991 0.009 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.991 0.009 0.000
S10-S19 Injuries to the neck
0.991 0.009 0.000
S91 Open wound of ankle and foot
0.991 0.009 0.000
D70 Agranulocytosis
0.991 0.009 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.990 0.010 0.000
H18 Other disorders of cornea
0.990 0.010 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.990 0.010 0.000
M45-M49 Spondylopathies
0.990 0.010 0.000
S40-S49 Injuries to the shoulder and upper arm
0.989 0.011 0.000
M06.0 Seronegative rheumatoid arthritis
0.989 0.011 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.989 0.011 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.989 0.011 0.000
D68.9 Coagulation defect, unspecified
0.989 0.011 0.000
J95-J99 Other diseases of the respiratory system
0.989 0.011 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.988 0.012 0.000
O47 False labour
0.988 0.012 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.988 0.012 0.000
M87 Osteonecrosis
0.988 0.012 0.000
F60-F69 Disorders of adult personality and behaviour
0.988 0.012 0.000
O66 Other obstructed labour
0.988 0.012 0.000
D75 Other diseases of blood and blood-forming organs
0.988 0.012 0.000
S02 Fracture of skull and facial bones
0.987 0.013 0.000
T90 Sequelae of injuries of head
0.987 0.013 0.000
T86 Failure and rejection of transplanted organs and tissues
0.987 0.013 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.987 0.013 0.000
C79.2 Secondary malignant neoplasm of skin
0.987 0.013 0.000
F30-F39 Mood [affective] disorders
0.987 0.013 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.987 0.013 0.000
O75.8 Other specified complications of labour and delivery
0.987 0.013 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.986 0.014 0.000
T39.1 4-Aminophenol derivatives
0.985 0.015 0.000
F43 Reaction to severe stress, and adjustment disorders
0.985 0.015 0.000
T87 Complications peculiar to reattachment and amputation
0.985 0.015 0.000
Y52 Agents primarily affecting the cardiovascular system
0.985 0.015 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.984 0.016 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.984 0.016 0.000
U80 Agent resistant to penicillin and related antibiotics
0.984 0.016 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.984 0.016 0.000
Chapter XI Diseases of the digestive system
0.983 0.017 0.000
E83.5 Disorders of calcium metabolism
0.983 0.017 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.983 0.017 0.000
S70.9 Superficial injury of hip and thigh, unspecified
0.983 0.017 0.000
D00-D09 In situ neoplasms
0.982 0.018 0.000
G82 Paraplegia and tetraplegia
0.982 0.018 0.000
O85-O92 Complications predominantly related to the puerperium
0.982 0.018 0.000
S50-S59 Injuries to the elbow and forearm
0.981 0.019 0.000
H72.0 Central perforation of tympanic membrane
0.981 0.019 0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)
0.980 0.020 0.000
T51.9 Alcohol, unspecified
0.980 0.020 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.980 0.020 0.000
Y84.2 Radiological procedure and radiotherapy
0.980 0.020 0.000
S06.3 Focal brain injury
0.980 0.020 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.979 0.021 0.000
L89.0 Stage I decubitus ulcer and pressure area
0.979 0.021 0.000
O00 Ectopic pregnancy
0.979 0.021 0.000
N00-N08 Glomerular diseases
0.978 0.022 0.000
B02 Zoster [herpes zoster]
0.978 0.022 0.000
C18 Malignant neoplasm of colon
0.978 0.022 0.000
S12 Fracture of neck
0.978 0.022 0.000
N64 Other disorders of breast
0.978 0.022 0.000
B15-B19 Viral hepatitis
0.977 0.023 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.977 0.023 0.000
B37 Candidiasis
0.977 0.023 0.000
G71 Primary disorders of muscles
0.977 0.023 0.000
N60-N64 Disorders of breast
0.976 0.024 0.000
O03 Spontaneous abortion
0.976 0.024 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.976 0.024 0.000
F60 Specific personality disorders
0.976 0.024 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.975 0.025 0.000
F33 Recurrent depressive disorder
0.975 0.025 0.000
G40 Epilepsy
0.975 0.025 0.000
D75.2 Essential thrombocytosis
0.975 0.025 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.974 0.026 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.974 0.026 0.000
N20-N23 Urolithiasis
0.974 0.026 0.000
G44 Other headache syndromes
0.974 0.026 0.000
M25.3 Other instability of joint
0.973 0.027 0.000
S91.3 Open wound of other parts of foot
0.973 0.027 0.000
G91 Hydrocephalus
0.973 0.027 0.000
M21.0 Valgus deformity, not elsewhere classified
0.973 0.027 0.000
T91 Sequelae of injuries of neck and trunk
0.973 0.027 0.000
Y57 Other and unspecified drugs and medicaments
0.973 0.027 0.000
M87.9 Osteonecrosis, unspecified
0.973 0.027 0.000
H73 Other disorders of tympanic membrane
0.973 0.027 0.000
S62 Fracture at wrist and hand level
0.972 0.028 0.000
O03.4 Incomplete, without complication
0.972 0.028 0.000
T40.2 Other opioids
0.972 0.028 0.000
D37.1 Stomach
0.971 0.029 0.000
C77.2 Intra-abdominal lymph nodes
0.971 0.029 0.000
J14 Pneumonia due to Haemophilus influenzae
0.971 0.029 0.000
C77.0 Lymph nodes of head, face and neck
0.971 0.029 0.000
C25 Malignant neoplasm of pancreas
0.971 0.029 0.000
C18.7 Sigmoid colon
0.970 0.030 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.969 0.031 0.000
Chapter IX Diseases of the circulatory system
0.968 0.032 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.967 0.033 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.966 0.034 0.000
N20 Calculus of kidney and ureter
0.966 0.034 0.000
X60-X84 Intentional self-harm
0.966 0.034 0.000
S06.30 Focal brain injury (without open intracranial wound)
0.966 0.034 0.000
K70-K77 Diseases of liver
0.964 0.036 0.000
C77.8 Lymph nodes of multiple regions
0.964 0.036 0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)
0.964 0.036 0.000
C15.9 Oesophagus, unspecified
0.964 0.036 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.964 0.036 0.000
M24.1 Other articular cartilage disorders
0.964 0.036 0.000
O62 Abnormalities of forces of labour
0.964 0.036 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.963 0.037 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.963 0.037 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.963 0.037 0.000
Q43 Other congenital malformations of intestine
0.963 0.037 0.000
G54 Nerve root and plexus disorders
0.963 0.037 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.963 0.037 0.000
H18.9 Disorder of cornea, unspecified
0.962 0.038 0.000
H60-H62 Diseases of external ear
0.962 0.038 0.000
D69 Purpura and other haemorrhagic conditions
0.962 0.038 0.000
E87.5 Hyperkalaemia
0.962 0.038 0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)
0.962 0.038 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.962 0.038 0.000
N20.0 Calculus of kidney
0.961 0.039 0.000
T87.6 Other and unspecified complications of amputation stump
0.961 0.039 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.961 0.039 0.000
G83 Other paralytic syndromes
0.961 0.039 0.000
Q80-Q89 Other congenital malformations
0.961 0.039 0.000
W50-W64 Exposure to animate mechanical forces
0.960 0.040 0.000
S72 Fracture of femur
0.959 0.041 0.000
Q50-Q56 Congenital malformations of genital organs
0.959 0.041 0.000
E20-E35 Disorders of other endocrine glands
0.959 0.041 0.000
F60.3 Emotionally unstable personality disorder
0.958 0.042 0.000
N64.8 Other specified disorders of breast
0.958 0.042 0.000
Y84.0 Cardiac catheterisation
0.957 0.043 0.000
N64.1 Fat necrosis of breast
0.957 0.043 0.000
G72 Other myopathies
0.957 0.043 0.000
M24.2 Disorder of ligament
0.956 0.044 0.000
O70 Perineal laceration during delivery
0.955 0.045 0.000
W19 Unspecified fall
0.954 0.046 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.954 0.046 0.000
C25.0 Head of pancreas
0.954 0.046 0.000
M90 Osteopathies in diseases classified elsewhere
0.954 0.046 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.954 0.046 0.000
S51 Open wound of forearm
0.954 0.046 0.000
S41 Open wound of shoulder and upper arm
0.954 0.046 0.000
O21 Excessive vomiting in pregnancy
0.953 0.047 0.000
T79-T79 Certain early complications of trauma
0.953 0.047 0.000
Y43 Primarily systemic agents
0.953 0.047 0.000
K11 Diseases of salivary glands
0.953 0.047 0.000
B37.9 Candidiasis, unspecified
0.952 0.048 0.000
M25.4 Effusion of joint
0.952 0.048 0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb
0.952 0.048 0.000
M91-M94 Chondropathies
0.952 0.048 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.951 0.049 0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
0.951 0.049 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.950 0.050 0.000
C80 Malignant neoplasm without specification of site
0.950 0.050 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.950 0.050 0.000
I10-I15 Hypertensive diseases
0.950 0.050 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.949 0.051 0.000
S62.3 Fracture of other metacarpal bone
0.949 0.051 0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.948 0.052 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.948 0.052 0.000
H66 Suppurative and unspecified otitis media
0.948 0.052 0.000
M25.8 Other specified joint disorders
0.948 0.052 0.000
E83.4 Disorders of magnesium metabolism
0.947 0.053 0.000
O72 Postpartum haemorrhage
0.947 0.053 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.946 0.054 0.000
O70.0 First degree perineal laceration during delivery
0.946 0.054 0.000
M60-M63 Disorders of muscles
0.946 0.054 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.946 0.054 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.945 0.055 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.945 0.055 0.000
O24 Diabetes mellitus in pregnancy
0.945 0.055 0.000
H74.3 Other acquired abnormalities of ear ossicles
0.944 0.056 0.000
G93.4 Encephalopathy, unspecified
0.944 0.056 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.944 0.056 0.000
Q60-Q64 Congenital malformations of the urinary system
0.943 0.057 0.000
Y95 Nosocomial condition
0.943 0.057 0.000
G82.2 Paraplegia, unspecified
0.943 0.057 0.000
I12 Hypertensive renal disease
0.942 0.058 0.000
A40 Streptococcal septicaemia
0.942 0.058 0.000
U51 Admission status on psychiatric patients
0.942 0.058 0.000
F43.2 Adjustment disorders
0.941 0.059 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.941 0.059 0.000
L89.2 Stage III decubitus ulcer
0.941 0.059 0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified
0.941 0.059 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.941 0.059 0.000
M47 Spondylosis
0.941 0.059 0.000
Y57.9 Drug or medicament, unspecified
0.940 0.060 0.000
H73.8 Other specified disorders of tympanic membrane
0.940 0.060 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.940 0.060 0.000
O20 Haemorrhage in early pregnancy
0.940 0.060 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.939 0.061 0.000
G71.1 Myotonic disorders
0.939 0.061 0.000
S70.0 Contusion of hip
0.939 0.061 0.000
V40-V49 Car occupant injured in transport accident
0.938 0.062 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.938 0.062 0.000
T51.0 Ethanol
0.938 0.062 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.937 0.063 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.937 0.063 0.000
O80-O84 Delivery
0.937 0.063 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.937 0.063 0.000
J60-J70 Lung diseases due to external agents
0.936 0.064 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.936 0.064 0.000
G40.8 Other epilepsy
0.936 0.064 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.936 0.064 0.000
C22.1 Intrahepatic bile duct carcinoma
0.936 0.064 0.000
G81 Hemiplegia
0.936 0.064 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.936 0.064 0.000
O66.0 Obstructed labour due to shoulder dystocia
0.935 0.065 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.935 0.065 0.000
W19.2 School, other institution and public administrative area
0.935 0.065 0.000
K35-K38 Diseases of appendix
0.935 0.065 0.000
M79.1 Myalgia
0.934 0.066 0.000
C22.9 Liver, unspecified
0.934 0.066 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.934 0.066 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.934 0.066 0.000
S12.2 Fracture of other specified cervical vertebra
0.934 0.066 0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)
0.933 0.067 0.000
J15.2 Pneumonia due to staphylococcus
0.933 0.067 0.000
S62.30 Fracture of other metacarpal bone (closed)
0.933 0.067 0.000
Q54 Hypospadias
0.932 0.068 0.000
D55-D59 Haemolytic anaemias
0.932 0.068 0.000
S20 Superficial injury of thorax
0.932 0.068 0.000
N76 Other inflammation of vagina and vulva
0.931 0.069 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.931 0.069 0.000
Q43.0 Meckel's diverticulum
0.931 0.069 0.000
F99-F99 Unspecified mental disorder
0.931 0.069 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.931 0.069 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.931 0.069 0.000
C45 Mesothelioma
0.930 0.070 0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)
0.930 0.070 0.000
D37.9 Digestive organ, unspecified
0.929 0.071 0.000
L89.9 Decubitus ulcer and pressure area, unspecified
0.929 0.071 0.000
O00.1 Tubal pregnancy
0.929 0.071 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.929 0.071 0.000
C18.1 Appendix
0.928 0.072 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.928 0.072 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.928 0.072 0.000
G72.9 Myopathy, unspecified
0.928 0.072 0.000
J15.7 Pneumonia due to Mycoplasma pneumoniae
0.927 0.073 0.000
U80.1 Methicillin resistant agent
0.927 0.073 0.000
G54.9 Nerve root and plexus disorder, unspecified
0.927 0.073 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.927 0.073 0.000
V80-V89 Other land transport accidents
0.926 0.074 0.000
S80 Superficial injury of lower leg
0.926 0.074 0.000
S92 Fracture of foot, except ankle
0.926 0.074 0.000
G90 Disorders of autonomic nervous system
0.926 0.074 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.925 0.075 0.000
S63.6 Sprain and strain of finger(s)
0.925 0.075 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.924 0.076 0.000
O86 Other puerperal infections
0.924 0.076 0.000
B02.2 Zoster with other nervous system involvement
0.924 0.076 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.924 0.076 0.000
U80.8 Agent resistant to other penicillin-related antibiotic
0.924 0.076 0.000
M79.83 Other specified soft tissue disorders (Forearm)
0.923 0.077 0.000
I12.0 Hypertensive renal disease with renal failure
0.923 0.077 0.000
D37.6 Liver, gallbladder and bile ducts
0.923 0.077 0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)
0.923 0.077 0.000
L93 Lupus erythematosus
0.923 0.077 0.000
O72.2 Delayed and secondary postpartum haemorrhage
0.923 0.077 0.000
Y84.4 Aspiration of fluid
0.923 0.077 0.000
T92.9 Sequelae of unspecified injury of upper limb
0.922 0.078 0.000
M90.7 Fracture of bone in neoplastic disease
0.922 0.078 0.000
Q76 Congenital malformations of spine and bony thorax
0.921 0.079 0.000
O43 Placental disorders
0.921 0.079 0.000
L80 Vitiligo
0.921 0.079 0.000
S83.6 Sprain and strain of other and unspecified parts of knee
0.920 0.080 0.000
T42.4 Benzodiazepines
0.920 0.080 0.000
M75.3 Calcific tendinitis of shoulder
0.920 0.080 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.920 0.080 0.000
S01 Open wound of head
0.919 0.081 0.000
K72 Hepatic failure, not elsewhere classified
0.919 0.081 0.000
G83.4 Cauda equina syndrome
0.919 0.081 0.000
E87.6 Hypokalaemia
0.919 0.081 0.000
D50-D53 Nutritional anaemias
0.918 0.082 0.000
M21.6 Other acquired deformities of ankle and foot
0.918 0.082 0.000
M89 Other disorders of bone
0.918 0.082 0.000
H74.4 Polyp of middle ear
0.918 0.082 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.918 0.082 0.000
M24.5 Contracture of joint
0.918 0.082 0.000
N64.9 Disorder of breast, unspecified
0.917 0.083 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.917 0.083 0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.916 0.084 0.000
T40.4 Other synthetic narcotics
0.915 0.085 0.000
E40-E46 Malnutrition
0.915 0.085 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.915 0.085 0.000
T93.0 Sequelae of open wound of lower limb
0.915 0.085 0.000
C32 Malignant neoplasm of larynx
0.915 0.085 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.914 0.086 0.000
S06.0 Concussion
0.914 0.086 0.000
S69 Other and unspecified injuries of wrist and hand
0.914 0.086 0.000
W50 Hit, struck, kicked, twisted, bitten or scratched by another person
0.914 0.086 0.000
J98 Other respiratory disorders
0.914 0.086 0.000
S22.1 Multiple fractures of thoracic spine
0.914 0.086 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.914 0.086 0.000
G93.6 Cerebral oedema
0.913 0.087 0.000
Y83.0 Surgical operation with transplant of whole organ
0.913 0.087 0.000
M21.1 Varus deformity, not elsewhere classified
0.913 0.087 0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)
0.913 0.087 0.000
C21 Malignant neoplasm of anus and anal canal
0.913 0.087 0.000
S41.1 Open wound of upper arm
0.913 0.087 0.000
R82 Other abnormal findings in urine
0.912 0.088 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.911 0.089 0.000
O82 Single delivery by Caesarean section
0.911 0.089 0.000
D07.5 Prostate
0.911 0.089 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.911 0.089 0.000
N02 Recurrent and persistent haematuria
0.911 0.089 0.000
F43.0 Acute stress reaction
0.911 0.089 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.911 0.089 0.000
H21 Other disorders of iris and ciliary body
0.910 0.090 0.000
D04 Carcinoma in situ of skin
0.910 0.090 0.000
C22.0 Liver cell carcinoma
0.910 0.090 0.000
T63 Toxic effect of contact with venomous animals
0.910 0.090 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.910 0.090 0.000
T86.1 Kidney transplant failure and rejection
0.910 0.090 0.000
C18.5 Splenic flexure
0.910 0.090 0.000
A46 Erysipelas
0.909 0.091 0.000
K09 Cysts of oral region, not elsewhere classified
0.909 0.091 0.000
D52 Folate deficiency anaemia
0.908 0.092 0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)
0.908 0.092 0.000
M62 Other disorders of muscle
0.907 0.093 0.000
Y84.1 Kidney dialysis
0.907 0.093 0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level
0.907 0.093 0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.907 0.093 0.000
B02.3 Zoster ocular disease
0.907 0.093 0.000
D80-D89 Certain disorders involving the immune mechanism
0.907 0.093 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.907 0.093 0.000
C18.3 Hepatic flexure
0.907 0.093 0.000
O00.9 Ectopic pregnancy, unspecified
0.907 0.093 0.000
G91.1 Obstructive hydrocephalus
0.906 0.094 0.000
Y40 Systemic antibiotics
0.906 0.094 0.000
B18 Chronic viral hepatitis
0.905 0.095 0.000
Q54.9 Hypospadias, unspecified
0.905 0.095 0.000
C15.5 Lower third of oesophagus
0.905 0.095 0.000
S29 Other and unspecified injuries of thorax
0.905 0.095 0.000
S72.3 Fracture of shaft of femur
0.904 0.096 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.904 0.096 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.904 0.096 0.000
C88 Malignant immunoproliferative diseases
0.903 0.097 0.000
S12.1 Fracture of second cervical vertebra
0.903 0.097 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.902 0.098 0.000
O42 Premature rupture of membranes
0.902 0.098 0.000
M40-M43 Deforming dorsopathies
0.902 0.098 0.000
L83 Acanthosis nigricans
0.902 0.098 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.902 0.098 0.000
S12.20 Fracture of other specified cervical vertebra (closed)
0.902 0.098 0.000
D52.9 Folate deficiency anaemia, unspecified
0.901 0.099 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.901 0.099 0.000
M06.3 Rheumatoid nodule
0.901 0.099 0.000
S90 Superficial injury of ankle and foot
0.901 0.099 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.900 0.100 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.900 0.100 0.000
E87.3 Alkalosis
0.900 0.100 0.000
M47.2 Other spondylosis with radiculopathy
0.900 0.100 0.000
S51.9 Open wound of forearm, part unspecified
0.900 0.100 0.000
M25.31 Other instability of joint (Shoulder region)
0.900 0.100 0.000
S05 Injury of eye and orbit
0.900 0.100 0.000
N76.0 Acute vaginitis
0.899 0.101 0.000
D43.2 Brain, unspecified
0.899 0.101 0.000
S22.2 Fracture of sternum
0.898 0.102 0.000
F43.1 Posttraumatic stress disorder
0.898 0.102 0.000
N99-N99 Other disorders of the genitourinary system
0.898 0.102 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.897 0.103 0.000
S00 Superficial injury of head
0.897 0.103 0.000
J11 Influenza, virus not identified
0.897 0.103 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.896 0.104 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.896 0.104 0.000
O24.4 Diabetes mellitus arising in pregnancy
0.896 0.104 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.896 0.104 0.000
T86.8 Failure and rejection of other transplanted organs and tissues
0.896 0.104 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.895 0.105 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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