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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12722598
log Bayes Factor = 17.1765
Chromosome 10   position 6,055,150  (GRCh37) Explore rs12722598 on Ensembl!
Variant rs12722598 is part of Cluster X0259

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
M23 Internal derangement of knee
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
0.999 0.001 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.999 0.001 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.995 0.005 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.993 0.007 0.000
C34 Malignant neoplasm of bronchus and lung
0.992 0.008 0.000
W00-W19 Falls
0.989 0.011 0.000
N10-N16 Renal tubulo-interstitial diseases
0.984 0.016 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.984 0.016 0.000
N60-N64 Disorders of breast
0.981 0.019 0.000
N13 Obstructive and reflux uropathy
0.980 0.020 0.000
W19 Unspecified fall
0.978 0.022 0.000
N30-N39 Other diseases of urinary system
0.977 0.023 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.975 0.025 0.000
B95-B98 Bacterial, viral and other infectious agents
0.975 0.025 0.000
M15-M19 Arthrosis
0.973 0.027 0.000
C34.9 Bronchus or lung, unspecified
0.970 0.030 0.000
C79 Secondary malignant neoplasm of other sites
0.970 0.030 0.000
N17-N19 Renal failure
0.970 0.030 0.000
M17 Gonarthrosis [arthrosis of knee]
0.967 0.033 0.000
N13.3 Other and unspecified hydronephrosis
0.967 0.033 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.965 0.035 0.000
W19.9 Unspecified place
0.961 0.039 0.000
N39 Other disorders of urinary system
0.961 0.039 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.960 0.040 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.959 0.041 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.958 0.042 0.000
M17.9 Gonarthrosis, unspecified
0.954 0.046 0.000
N18 Chronic renal failure
0.950 0.050 0.000
M70-M79 Other soft tissue disorders
0.947 0.053 0.000
M25 Other joint disorders, not elsewhere classified
0.946 0.054 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.945 0.055 0.000
A00-A09 Intestinal infectious diseases
0.945 0.055 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.942 0.058 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.935 0.065 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.933 0.067 0.000
N39.3 Stress incontinence
0.932 0.068 0.000
Chapter VI Diseases of the nervous system
0.928 0.072 0.000
M45-M49 Spondylopathies
0.927 0.073 0.000
N64 Other disorders of breast
0.926 0.074 0.000
L60-L75 Disorders of skin appendages
0.925 0.075 0.000
Chapter VII Diseases of the eye and adnexa
0.920 0.080 0.000
N18.3 Chronic kidney disease, stage 3
0.916 0.084 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.913 0.087 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.913 0.087 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.911 0.089 0.000
M17.1 Other primary gonarthrosis
0.909 0.091 0.000
C34.1 Upper lobe, bronchus or lung
0.898 0.102 0.000
M25.7 Osteophyte
0.897 0.103 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.895 0.105 0.000
H30-H36 Disorders of choroid and retina
0.893 0.107 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.893 0.107 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.891 0.109 0.000
L82 Seborrhoeic keratosis
0.890 0.110 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.887 0.113 0.000
N25-N29 Other disorders of kidney and ureter
0.885 0.115 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.882 0.118 0.000
G90-G99 Other disorders of the nervous system
0.880 0.120 0.000
N60 Benign mammary dysplasia
0.876 0.124 0.000
A30-A49 Other bacterial diseases
0.871 0.129 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.871 0.129 0.000
N39.8 Other specified disorders of urinary system
0.869 0.131 0.000
L72.1 Trichilemmal cyst
0.868 0.132 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.864 0.136 0.000
B35-B49 Mycoses
0.857 0.143 0.000
C34.2 Middle lobe, bronchus or lung
0.856 0.144 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.855 0.145 0.000
N18.9 Chronic renal failure, unspecified
0.855 0.145 0.000
C50-C50 Malignant neoplasm of breast
0.853 0.146 0.000
C51-C58 Malignant neoplasms of female genital organs
0.853 0.147 0.000
E10-E14 Diabetes mellitus
0.849 0.151 0.000
L89 Decubitus ulcer
0.848 0.152 0.000
M80-M85 Disorders of bone density and structure
0.843 0.157 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.840 0.160 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.839 0.161 0.000
M23.4 Loose body in knee
0.839 0.161 0.000
M86-M90 Other osteopathies
0.839 0.161 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.837 0.163 0.000
L91 Hypertrophic disorders of skin
0.837 0.163 0.000
W19.2 School, other institution and public administrative area
0.834 0.166 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.834 0.166 0.000
H36 Retinal disorders in diseases classified elsewhere
0.834 0.166 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.833 0.167 0.000
N39.9 Disorder of urinary system, unspecified
0.833 0.167 0.000
N64.5 Other signs and symptoms in breast
0.826 0.174 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.825 0.175 0.000
N13.4 Hydroureter
0.818 0.181 0.000
M75 Shoulder lesions
0.817 0.183 0.000
N64.9 Disorder of breast, unspecified
0.816 0.184 0.000
M46 Other inflammatory spondylopathies
0.813 0.186 0.000
M23.3 Other meniscus derangements
0.813 0.187 0.000
Chapter XXII Codes for special purposes
0.809 0.191 0.000
M00-M03 Infectious arthropathies
0.809 0.191 0.000
Chapter VIII Diseases of the ear and mastoid process
0.808 0.192 0.000
M47 Spondylosis
0.808 0.192 0.000
H33 Retinal detachments and breaks
0.806 0.194 0.000
L80 Vitiligo
0.805 0.195 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.805 0.195 0.000
N61 Inflammatory disorders of breast
0.805 0.195 0.000
N30 Cystitis
0.804 0.195 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.804 0.196 0.000
L72.8 Other follicular cysts of skin and subcutaneous tissue
0.803 0.197 0.000
L50-L54 Urticaria and erythema
0.802 0.198 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.802 0.198 0.000
V10-V19 Pedal cyclist injured in transport accident
0.800 0.200 0.000
D70 Agranulocytosis
0.800 0.200 0.000
M23.8 Other internal derangements of knee
0.798 0.202 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.795 0.205 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.793 0.206 0.000
W20-W49 Exposure to inanimate mechanical forces
0.793 0.207 0.000
M25.77 Osteophyte (Ankle and foot)
0.792 0.208 0.000
E11 Non-insulin-dependent diabetes mellitus
0.792 0.208 0.000
M24 Other specific joint derangements
0.791 0.209 0.000
H36.0 Diabetic retinopathy
0.791 0.209 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.790 0.210 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.788 0.212 0.000
M25.4 Effusion of joint
0.784 0.216 0.000
M91-M94 Chondropathies
0.783 0.217 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.783 0.217 0.000
C34.3 Lower lobe, bronchus or lung
0.782 0.218 0.000
M35 Other systemic involvement of connective tissue
0.781 0.219 0.000
Y43 Primarily systemic agents
0.780 0.220 0.000
L89.1 Stage II decubitus ulcer
0.777 0.223 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.776 0.224 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.771 0.229 0.000
H53-H54 Visual disturbances and blindness
0.770 0.230 0.000
M77 Other enthesopathies
0.768 0.232 0.000
L93 Lupus erythematosus
0.768 0.232 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.767 0.233 0.000
N36 Other disorders of urethra
0.765 0.235 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.764 0.236 0.000
M40-M43 Deforming dorsopathies
0.763 0.237 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.763 0.237 0.000
N99-N99 Other disorders of the genitourinary system
0.762 0.238 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.761 0.239 0.000
E70-E90 Metabolic disorders
0.760 0.240 0.000
M25.71 Osteophyte (Shoulder region)
0.760 0.240 0.000
X20-X29 Contact with venomous animals and plants
0.759 0.241 0.000
B15-B19 Viral hepatitis
0.758 0.242 0.000
W08 Fall involving other furniture
0.756 0.244 0.000
B02 Zoster [herpes zoster]
0.756 0.244 0.000
B37 Candidiasis
0.755 0.245 0.000
A41 Other septicaemia
0.755 0.245 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.754 0.245 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.754 0.246 0.000
C64-C68 Malignant neoplasms of urinary tract
0.754 0.246 0.000
H33.0 Retinal detachment with retinal break
0.754 0.246 0.000
C83.3 Large cell (diffuse)
0.753 0.247 0.000
N00-N08 Glomerular diseases
0.752 0.248 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.751 0.249 0.000
C79.2 Secondary malignant neoplasm of skin
0.751 0.249 0.000
M71 Other bursopathies
0.749 0.250 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.749 0.251 0.000
C50 Malignant neoplasm of breast
0.749 0.251 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.749 0.251 0.000
N34 Urethritis and urethral syndrome
0.747 0.253 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.746 0.254 0.000
D00-D09 In situ neoplasms
0.746 0.254 0.000
L91.8 Other hypertrophic disorders of skin
0.745 0.255 0.000
N17 Acute renal failure
0.745 0.255 0.000
W19.4 Street and highway
0.745 0.255 0.000
W10 Fall on and from stairs and steps
0.745 0.255 0.000
Y83.8 Other surgical procedures
0.744 0.256 0.000
Y83.4 Other reconstructive surgery
0.743 0.257 0.000
E11.3 With ophthalmic complications
0.743 0.257 0.000
M47.8 Other spondylosis
0.742 0.258 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.741 0.259 0.000
C34.0 Main bronchus
0.740 0.260 0.000
A80-A89 Viral infections of the central nervous system
0.739 0.260 0.000
M21 Other acquired deformities of limbs
0.738 0.262 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.738 0.262 0.000
M75.1 Rotator cuff syndrome
0.737 0.263 0.000
A08 Viral and other specified intestinal infections
0.737 0.263 0.000
N30.2 Other chronic cystitis
0.736 0.264 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.736 0.264 0.000
M25.0 Haemarthrosis
0.736 0.264 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.734 0.266 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.733 0.267 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.732 0.268 0.000
C92 Myeloid leukaemia
0.732 0.268 0.000
G93 Other disorders of brain
0.731 0.269 0.000
M79.8 Other specified soft tissue disorders
0.730 0.270 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.729 0.271 0.000
N39.4 Other specified urinary incontinence
0.728 0.272 0.000
V20-V29 Motorcycle rider injured in transport accident
0.728 0.272 0.000
N18.4 Chronic kidney disease, stage 4
0.727 0.273 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.727 0.273 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.727 0.273 0.000
W13 Fall from, out of or through building or structure
0.725 0.275 0.000
N28.8 Other specified disorders of kidney and ureter
0.724 0.276 0.000
M23.49 Loose body in knee-Unspec lig/men
0.723 0.277 0.000
N60.0 Solitary cyst of breast
0.723 0.277 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.722 0.278 0.000
D60-D64 Aplastic and other anaemias
0.721 0.279 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.720 0.280 0.000
D55-D59 Haemolytic anaemias
0.720 0.280 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.719 0.281 0.000
E40-E46 Malnutrition
0.718 0.282 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.718 0.282 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
M34 Systemic sclerosis
0.717 0.283 0.000
M33 Dermatopolymyositis
0.717 0.283 0.000
M32 Systemic lupus erythematosus
0.717 0.283 0.000
M30 Polyarteritis nodosa and related conditions
0.717 0.283 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.717 0.283 0.000
M23.9 Internal derangement of knee, unspecified
0.717 0.283 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.717 0.283 0.000
M23.5 Chronic instability of knee
0.717 0.283 0.000
M23.1 Discoid meniscus (congenital)
0.717 0.283 0.000
M23.0 Cystic meniscus
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
Y00-Y09 Assault
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X60-X84 Intentional self-harm
0.717 0.283 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.717 0.283 0.000
X50-X57 Overexertion, travel and privation
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X10-X19 Contact with heat and hot substances
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.717 0.283 0.000
W75-W84 Other accidental threats to breathing
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
W50-W64 Exposure to animate mechanical forces
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V80-V89 Other land transport accidents
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V40-V49 Car occupant injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.717 0.283 0.000
B99-B99 Other infectious diseases
0.717 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.717 0.283 0.000
B65-B83 Helminthiases
0.717 0.283 0.000
B50-B64 Protozoal diseases
0.717 0.283 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.717 0.283 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.717 0.283 0.000
A75-A79 Rickettsioses
0.717 0.283 0.000
A70-A74 Other diseases caused by chlamydiae
0.717 0.283 0.000
A65-A69 Other spirochaetal diseases
0.717 0.283 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.717 0.283 0.000
A20-A28 Certain zoonotic bacterial diseases
0.717 0.283 0.000
A15-A19 Tuberculosis
0.717 0.283 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.716 0.283 0.000
N63 Unspecified lump in breast
0.716 0.284 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.713 0.287 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.713 0.287 0.000
C32 Malignant neoplasm of larynx
0.713 0.287 0.000
C31 Malignant neoplasm of accessory sinuses
0.713 0.287 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.713 0.287 0.000
C37 Malignant neoplasm of thymus
0.713 0.287 0.000
C33 Malignant neoplasm of trachea
0.713 0.287 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.711 0.289 0.000
C34.8 Overlapping lesion of bronchus and lung
0.711 0.289 0.000
M31 Other necrotising vasculopathies
0.711 0.289 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.711 0.289 0.000
H65-H75 Diseases of middle ear and mastoid
0.709 0.291 0.000
W18 Other fall on same level
0.709 0.291 0.000
W17 Other fall from one level to another
0.709 0.291 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.709 0.291 0.000
W15 Fall from cliff
0.709 0.291 0.000
W14 Fall from tree
0.709 0.291 0.000
W12 Fall on and from scaffolding
0.709 0.291 0.000
W11 Fall on and from ladder
0.709 0.291 0.000
W09 Fall involving playground equipment
0.709 0.291 0.000
W07 Fall involving chair
0.709 0.291 0.000
W06 Fall involving bed
0.709 0.291 0.000
W05 Fall involving wheelchair
0.709 0.291 0.000
W04 Fall while being carried or supported by other persons
0.709 0.291 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.709 0.291 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.709 0.291 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.709 0.291 0.000
W00 Fall on same level involving ice and snow
0.709 0.291 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.709 0.291 0.000
M05-M14 Inflammatory polyarthropathies
0.707 0.293 0.000
G95 Other diseases of spinal cord
0.707 0.293 0.000
C50.9 Breast, unspecified
0.707 0.293 0.000
N64.8 Other specified disorders of breast
0.707 0.293 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.706 0.294 0.000
N60.2 Fibroadenosis of breast
0.706 0.294 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.706 0.294 0.000
N15 Other renal tubulo-interstitial diseases
0.706 0.294 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.706 0.294 0.000
N11 Chronic tubulo-interstitial nephritis
0.706 0.294 0.000
N10 Acute tubulo-interstitial nephritis
0.706 0.294 0.000
Y84.0 Cardiac catheterisation
0.706 0.294 0.000
L10-L14 Bullous disorders
0.705 0.295 0.000
H35 Other retinal disorders
0.704 0.296 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.703 0.297 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.702 0.298 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.702 0.298 0.000
N13.6 Pyonephrosis
0.702 0.298 0.000
W19.8 Other specified place
0.701 0.298 0.000
W19.5 Trade and service area
0.701 0.298 0.000
W19.0 Home
0.701 0.298 0.000
W19.7 Farm
0.701 0.298 0.000
W19.6 Industrial and construction area
0.701 0.298 0.000
W19.3 Sports and athletics area
0.701 0.298 0.000
W19.1 Residential institution
0.701 0.298 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.700 0.299 0.000
N37 Urethral disorders in diseases classified elsewhere
0.700 0.300 0.000
N33 Bladder disorders in diseases classified elsewhere
0.700 0.300 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.699 0.301 0.000
Y43.3 Other antineoplastic drugs
0.698 0.302 0.000
M15 Polyarthrosis
0.698 0.302 0.000
M85 Other disorders of bone density and structure
0.698 0.302 0.000
N76 Other inflammation of vagina and vulva
0.698 0.302 0.000
E65-E68 Obesity and other hyperalimentation
0.696 0.304 0.000
Y83.9 Surgical procedure, unspecified
0.696 0.304 0.000
C79.6 Secondary malignant neoplasm of ovary
0.695 0.305 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.695 0.305 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.695 0.305 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.695 0.305 0.000
N60.8 Other benign mammary dysplasias
0.695 0.305 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.694 0.306 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.694 0.306 0.000
M17.5 Other secondary gonarthrosis
0.694 0.306 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.694 0.306 0.000
M17.3 Other posttraumatic gonarthrosis
0.694 0.306 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.694 0.306 0.000
M65-M68 Disorders of synovium and tendon
0.694 0.306 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.693 0.307 0.000
H43-H45 Disorders of vitreous body and globe
0.692 0.308 0.000
L73 Other follicular disorders
0.691 0.309 0.000
N39.2 Orthostatic proteinuria, unspecified
0.689 0.311 0.000
N39.1 Persistent proteinuria, unspecified
0.689 0.311 0.000
M87 Osteonecrosis
0.688 0.312 0.000
N92 Excessive, frequent and irregular menstruation
0.688 0.312 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.687 0.313 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.687 0.313 0.000
L94 Other localised connective tissue disorders
0.687 0.313 0.000
L87 Transepidermal elimination disorders
0.687 0.313 0.000
L88 Pyoderma gangrenosum
0.687 0.313 0.000
L86 Keratoderma in diseases classified elsewhere
0.687 0.313 0.000
L83 Acanthosis nigricans
0.687 0.313 0.000
B02.9 Zoster without complication
0.686 0.314 0.000
C81 Hodgkin's disease
0.685 0.315 0.000
E00-E07 Disorders of thyroid gland
0.684 0.316 0.000
N60.3 Fibrosclerosis of breast
0.682 0.318 0.000
N62 Hypertrophy of breast
0.682 0.318 0.000
N18.8 Other chronic renal failure
0.681 0.319 0.000
N18.2 Chronic kidney disease, stage 2
0.681 0.319 0.000
N18.1 Chronic kidney disease, stage 1
0.681 0.319 0.000
N93 Other abnormal uterine and vaginal bleeding
0.681 0.319 0.000
C80 Malignant neoplasm without specification of site
0.681 0.319 0.000
N60.4 Mammary duct ectasia
0.680 0.320 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.679 0.321 0.000
M76 Enthesopathies of lower limb, excluding foot
0.679 0.321 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.679 0.321 0.000
C91 Lymphoid leukaemia
0.679 0.321 0.000
M25.9 Joint disorder, unspecified
0.678 0.322 0.000
M25.8 Other specified joint disorders
0.678 0.322 0.000
M25.3 Other instability of joint
0.678 0.322 0.000
M25.2 Flail joint
0.678 0.322 0.000
M25.1 Fistula of joint
0.678 0.322 0.000
N80 Endometriosis
0.678 0.322 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.678 0.322 0.000
C95 Leukaemia of unspecified cell type
0.678 0.322 0.000
C94 Other leukaemias of specified cell type
0.678 0.322 0.000
C93 Monocytic leukaemia
0.678 0.322 0.000
C88 Malignant immunoproliferative diseases
0.678 0.322 0.000
C86 Other specified types of T/NK-cell lymphoma
0.678 0.322 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.678 0.322 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.678 0.322 0.000
A07 Other protozoal intestinal diseases
0.677 0.323 0.000
A06 Amoebiasis
0.677 0.323 0.000
A05 Other bacterial foodborne intoxications
0.677 0.323 0.000
A03 Shigellosis
0.677 0.323 0.000
A02 Other Salmonella infections
0.677 0.323 0.000
A01 Typhoid and paratyphoid fevers
0.677 0.323 0.000
A00 Cholera
0.677 0.323 0.000
E50-E64 Other nutritional deficiencies
0.677 0.323 0.000
A49 Bacterial infection of unspecified site
0.676 0.323 0.000
E14 Unspecified diabetes mellitus
0.676 0.324 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.675 0.324 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.675 0.324 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.675 0.324 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.675 0.324 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.674 0.326 0.000
M48 Other spondylopathies
0.673 0.327 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.673 0.327 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.672 0.328 0.000
L53 Other erythematous conditions
0.672 0.328 0.000
M00 Pyogenic arthritis
0.672 0.328 0.000
Y84.2 Radiological procedure and radiotherapy
0.672 0.328 0.000
M25.76 Osteophyte (Lower leg)
0.671 0.329 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.671 0.329 0.000
M84 Disorders of continuity of bone
0.667 0.333 0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.666 0.334 0.000
H90-H95 Other disorders of ear
0.666 0.334 0.000
G70-G73 Diseases of myoneural junction and muscle
0.666 0.334 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.666 0.334 0.000
M35.0 Sicca syndrome [Sjogren]
0.665 0.335 0.000
B25-B34 Other viral diseases
0.665 0.335 0.000
C53 Malignant neoplasm of cervix uteri
0.665 0.335 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.665 0.335 0.000
M49 Spondylopathies in diseases classified elsewhere
0.664 0.335 0.000
N64.4 Mastodynia
0.664 0.336 0.000
N64.3 Galactorrhoea not associated with childbirth
0.664 0.336 0.000
N64.2 Atrophy of breast
0.664 0.336 0.000
N64.0 Fissure and fistula of nipple
0.664 0.336 0.000
E87.7 Fluid overload
0.664 0.336 0.000
L75 Apocrine sweat disorders
0.663 0.336 0.000
L74 Eccrine sweat disorders
0.663 0.336 0.000
L71 Rosacea
0.663 0.336 0.000
L70 Acne
0.663 0.336 0.000
L68 Hypertrichosis
0.663 0.336 0.000
L67 Hair colour and hair shaft abnormalities
0.663 0.336 0.000
L66 Cicatricial alopecia [scarring hair loss]
0.663 0.336 0.000
L65 Other nonscarring hair loss
0.663 0.336 0.000
L64 Androgenic alopecia
0.663 0.336 0.000
L63 Alopecia areata
0.663 0.336 0.000
L62 Nail disorders in diseases classified elsewhere
0.663 0.336 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.662 0.338 0.000
G30-G32 Other degenerative diseases of the nervous system
0.661 0.339 0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.660 0.340 0.000
C51 Malignant neoplasm of vulva
0.660 0.340 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.660 0.340 0.000
N94.1 Dyspareunia
0.659 0.341 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.659 0.341 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.657 0.343 0.000
H54 Blindness and low vision
0.655 0.345 0.000
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin
0.655 0.345 0.000
Y83.5 Amputation of limb(s)
0.655 0.345 0.000
Y83.0 Surgical operation with transplant of whole organ
0.655 0.345 0.000
C56 Malignant neoplasm of ovary
0.654 0.346 0.000
H10-H13 Disorders of conjunctiva
0.653 0.346 0.000
E87.5 Hyperkalaemia
0.653 0.347 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.653 0.347 0.000
M86 Osteomyelitis
0.653 0.347 0.000
N13.8 Other obstructive and reflux uropathy
0.652 0.348 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.652 0.348 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.652 0.348 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.652 0.348 0.000
N92.0 Excessive and frequent menstruation with regular cycle
0.652 0.348 0.000
M45 Ankylosing spondylitis
0.651 0.349 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.651 0.349 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.651 0.349 0.000
H25-H28 Disorders of lens
0.650 0.350 0.000
N18.0 End-stage renal disease
0.650 0.350 0.000
H55-H59 Other disorders of eye and adnexa
0.650 0.350 0.000
M47.82 Other spondylosis (Cervical region)
0.650 0.350 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.650 0.350 0.000
G40-G47 Episodic and paroxysmal disorders
0.649 0.351 0.000
G20-G26 Extrapyramidal and movement disorders
0.646 0.354 0.000
B91 Sequelae of poliomyelitis
0.646 0.354 0.000
N93.8 Other specified abnormal uterine and vaginal bleeding
0.645 0.355 0.000
M25.47 Effusion of joint (Ankle and foot)
0.644 0.355 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.644 0.356 0.000
M25.79 Osteophyte (Site unspecified)
0.643 0.357 0.000
M25.74 Osteophyte (Hand)
0.643 0.357 0.000
M25.73 Osteophyte (Forearm)
0.643 0.357 0.000
M25.72 Osteophyte (Upper arm)
0.643 0.357 0.000
M25.70 Osteophyte (Multiple sites)
0.643 0.357 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.643 0.357 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.643 0.357 0.000
L20-L30 Dermatitis and eczema
0.643 0.357 0.000
M18 Arthrosis of first carpometacarpal joint
0.642 0.358 0.000
M24.1 Other articular cartilage disorders
0.642 0.358 0.000
W22 Striking against or struck by other objects
0.641 0.358 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.640 0.359 0.000
H31 Other disorders of choroid
0.640 0.359 0.000
H30 Chorioretinal inflammation
0.640 0.359 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.640 0.360 0.000
Y79 Orthopaedic devices associated with adverse incidents
0.640 0.360 0.000
L72.2 Steatocystoma multiplex
0.640 0.360 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.640 0.360 0.000
L81 Other disorders of pigmentation
0.639 0.361 0.000
N81 Female genital prolapse
0.638 0.362 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.638 0.362 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.638 0.362 0.000
H72 Perforation of tympanic membrane
0.637 0.363 0.000
M47.2 Other spondylosis with radiculopathy
0.637 0.363 0.000
L90 Atrophic disorders of skin
0.637 0.363 0.000
N64.1 Fat necrosis of breast
0.635 0.364 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.634 0.366 0.000
N27 Small kidney of unknown cause
0.634 0.366 0.000
N25 Disorders resulting from impaired renal tubular function
0.634 0.366 0.000
N26 Unspecified contracted kidney
0.634 0.366 0.000
H40-H42 Glaucoma
0.634 0.366 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.633 0.366 0.000
B37.8 Candidiasis of other sites
0.633 0.367 0.000
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified
0.633 0.367 0.000
L85 Other epidermal thickening
0.632 0.368 0.000
L93.0 Discoid lupus erythematosus
0.631 0.368 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.631 0.369 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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